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393 results on '"Cestari, Dean M."'

1. Natural history of patients with Leber hereditary optic neuropathy—results from the REALITY study

Author

Yu-Wai-Man, Patrick, Newman, Nancy J., Carelli, Valerio, La Morgia, Chiara, Biousse, Valérie, Bandello, Francesco M., Clermont, Catherine Vignal, Campillo, Lorena Castillo, Leruez, Stephanie, Moster, Mark L., Cestari, Dean M., Foroozan, Rod, Sadun, Alfredo, Karanjia, Rustum, Jurkute, Neringa, Blouin, Laure, Taiel, Magali, and Sahel, José-Alain

Published
2022
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2. Workup for Optic Atrophy

Author

Chwalisz, Bart, Cestari, Dean M., Borruat, François-Xavier, Lee, Andrew G., editor, Sinclair, Alexandra J., editor, Sadaka, Ama, editor, Berry, Shauna, editor, and Mollan, Susan P., editor

Published
2019
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11. Steroid-sparing maintenance immunotherapy for MOG-IgG associated disorder

Author

Chen, John J., Flanagan, Eoin P., Bhatti, M. Tariq, Jitprapaikulsan, Jiraporn, Dubey, Divyanshu, Lopez Chiriboga, Alfonso (Sebastian) S., Fryer, James P., Weinshenker, Brian G., McKeon, Andrew, Tillema, Jan-Mendelt, Lennon, Vanda A., Lucchinetti, Claudia F., Kunchok, Amy, McClelland, Collin M., Lee, Michael S., Bennett, Jeffrey L., Pelak, Victoria S., Van Stavern, Gregory, Adesina, Ore-Ofe O., Eggenberger, Eric R., Acierno, Marie D., Wingerchuk, Dean M., Lam, Byron L., Moss, Heather, Beres, Shannon, Gilbert, Aubrey L., Shah, Veeral, Armstrong, Grayson, Heidary, Gena, Cestari, Dean M., Stiebel-Kalish, Hadas, and Pittock, Sean J.

Published
2020
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33. Traumatic rupture of the inferior rectus muscle: case report and review of the literature.

Author

Amer, Mona M., Cestari, Dean M., Yoon, Michael K., and Armstrong, Grayson W.

Subjects
*TRAUMA surgery, *EYE muscles, STRABISMUS surgery
Abstract

Traumatic inferior rectus muscle rupture secondary to blunt injury in the absence of associated orbital or ocular fractures or injury is rarely encountered, and there are limited published reports on subsequent surgical repair. We present the case of a 74-year-old man with complete inferior rectus transection following a fall with facial strike. A computed tomography scan of the face was unremarkable. Surgical exploration and repair of the muscle was performed by hooking the inferior oblique muscle to identify the inferior rectus muscle. Subsequent strabismus surgery was performed for residual binocular diplopia, resulting in excellent anatomic and visual outcomes and postoperative ocular alignment. [ABSTRACT FROM AUTHOR]

Published
2023
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35. Case 40-2008: a 26-year-old man with blurred vision

Author

Cestari, Dean M., Cunnane, Mary E., Metson, Ralph B., and Faquin, William C.

Subjects
Sinusitis -- Care and treatment, Sinusitis -- Diagnosis, Sinusitis -- Case studies
Abstract

A case study of a 26-year-old man with blurred vision is discussed to better understand a case of allergic fungal sinusitis along with compression of the right optic nerve. The clinical processes undertaken to confirm the prognosis are presented, as it appeared to be showing signs of optic neuropathy.

Published
2008

44. Elevated Intracranial Pressure Associated With Exogenous Hormonal Therapy Used for Gender Affirmation.

Author

Nguyen, Huy V., Gilbert, Aubrey L., Fortin, Elizabeth, Vodopivec, Ivana, Torun, Nurhan, Chwalisz, Bart K., Cestari, Dean M., and Rizzo III, Joseph F.

Abstract

Background: Addison disease, corticosteroid withdrawal, and taking synthetic growth hormone have been linked with development of intracranial hypertension, but there is still debate on whether administration of other exogenous hormones plays a role in precipitating elevated pressure. The growing use of hormonal therapy for gender affirmation provides an opportunity to explore this possibility. Methods: All transgender patients taking exogenous hormones for female-to-male (FTM) and male-to-female (MTF) transitions who were diagnosed with intracranial hypertension at Massachusetts Eye and Ear Infirmary, Massachusetts General Hospital and Beth Israel Deaconess Medical Center between August 2014 and November 2018 were included in a retrospective review. Visual acuity, type, and dose of exogenous hormone, visual field testing, clinical exam, results of neuroimaging and lumbar puncture, and treatment modalities were catalogued and analyzed. Results: Six transgender individuals were identified. Five were FTM, with an average hormone treatment time of 18.4 months, and one was MTF who had been treated with hormones for 4 years. The average age of all patients was 23.5 years. The average time between onset of symptoms and presentation was 5 months. Fifty percent of the patients reported pulse-synchronous tinnitus, 83% reported positional headache, 33% reported transient visual obscurations, and 16% reported diplopia. Lumbar punctures performed on 4 of the patients revealed elevated opening pressures and normal cerebrospinal fluid constituents. MRI findings consistent with elevated intracranial pressure (ICP) were present in the other 2 patients in whom lumbar puncture was unsuccessful. Four patients were treated with acetazolamide and one was treated with topiramate, with an average follow-up time of 15.7 months. All patients demonstrated bilateral optic disc swelling, and all maintained normal acuity and color vision. Performance on visual field testing was not significantly affected in any patient. Conclusions: This is the largest reported series to date of gender-transitioning patients with intracranial hypertension, including one novel MTF conversion. These observations warrant further investigation into the possible link of exogenous hormonal therapy and elevated ICP and any mechanisms or confounders underlying this potential association. [ABSTRACT FROM AUTHOR]

Published
2021
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47. Sinonasal Chondrosarcoma Presenting With Isolated Severe Vision Loss

Author

Nguyen, Michael T. B., Farahvash, Armin, Dickson, Brendan C., Lee, John M., Cusimano, Michael D., Tsang, Derek S., Micieli, Jonathan A., Ko, Melissa W., Cestari, Dean M., and Quiros, Peter

Abstract

A 24-year-old man presented with a 2-month history of progressive, painless vision loss in the right eye, with no history of headache, nasal congestion, rhinorrhea, or epistaxis. His visual acuity was counting fingers at 1 ft in the right eye and 20 of 20 in the left eye with a right relative afferent pupillary defect and mild temporal optic disc pallor. MRI of the brain and orbits showed a mass involving bilateral ethmoid and sphenoid sinuses and right nasal cavity. He underwent urgent extended endoscopic endonasal transsphenoidal approach for resection of the sinonasal skull base tumor and photon radiation therapy. Pathology revealed a well-differentiated cartilaginous neoplasm with focal areas of entrapped native bone, consistent with a chondrosarcoma WHO grade I/III. At 6-month follow-up after surgery, he had a visual acuity of 20/40 in the right eye and 20/20 in the left eye. Malignant tumors from the sinonasal area should be kept in the differential diagnosis for compressive optic neuropathies and may present with vision loss even in the absence of nasal or sinus symptoms.

Published
2021
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