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15 results on '"Ceresoli-Borroni, Gianpiera"'

4. Continuous, Subcutaneous Apomorphine Infusion for Persistent Motor Fluctuations in Parkinson’s Disease: Full results of the AP2-3000 open-label study (S32.008)

Author

Isaacson, Stuart, primary, Ceresoli-Borroni, Gianpiera, additional, Espay, Alberto, additional, Pahwa, Rajesh, additional, Agarwal, Pinky, additional, Shill, Holly, additional, Hui, Jennifer, additional, Dashtipour, Khashayar, additional, Lew, Mark, additional, Qin, Peibing, additional, Nasser, Azmi, additional, and LeWitt, Peter, additional

Published
2023
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6. Supplemental_material – Supplemental material for A Double-Blind, Randomized Study of Extended-Release Molindone for Impulsive Aggression in ADHD

Author

Ceresoli-Borroni, Gianpiera, Nasser, Azmi, Toyin Adewole, Tesfaye Liranso, Jiahong Xu, Schwabe, Stefan, and Findling, Robert L.

Subjects
FOS: Psychology, 170199 Psychology not elsewhere classified, Education
Abstract

Supplemental material, Supplemental_material for A Double-Blind, Randomized Study of Extended-Release Molindone for Impulsive Aggression in ADHD by Gianpiera Ceresoli-Borroni, Azmi Nasser, Toyin Adewole, Tesfaye Liranso, Jiahong Xu, Stefan Schwabe and Robert L. Findling in Journal of Attention Disorders

Published
2020
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8. Closing the gap: unmet needs of individuals with impulsive aggressive behavior observed in children and adolescents

Author

Robb, Adelaide S., primary, Connor, Daniel F., additional, Amann, Birgit H., additional, Vitiello, Benedetto, additional, Nasser, Azmi, additional, O’Neal, Welton, additional, Schwabe, Stefan, additional, Ceresoli-Borroni, Gianpiera, additional, Newcorn, Jeffrey H., additional, Candler, Shawn A., additional, Buitelaar, Jan K., additional, and Findling, Robert L., additional

Published
2020
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9. A Double-Blind, Randomized Study of Extended-Release Molindone for Impulsive Aggression in ADHD.

Author

Ceresoli-Borroni, Gianpiera, Nasser, Azmi, Adewole, Toyin, Liranso, Tesfaye, Xu, Jiahong, Schwabe, Stefan, and Findling, Robert L.

Subjects
ATTENTION-deficit hyperactivity disorder, BEHAVIOR therapy, HEADACHE, STIMULANTS, AGGRESSION (Psychology)
Abstract

Objective: To evaluate efficacy and safety of SPN-810 (extended-release molindone) in a Phase-2b, randomized, double-blind, placebo-controlled, dose-ranging study of children (6–12 years) with ADHD and persistent impulsive aggression (IA). Method: After lead-in, children were randomized to (a) placebo (N = 31); (b) low-dose (N = 29, 12/18 mg/day); (c) medium-dose (N = 30, 24/36 mg/day); and (4) high-dose (N = 31, 36/54 mg/day) groups. Treatment included ~2.5-week titration, 3-week maintenance, and 1-week tapering/conversion, alongside existing monotherapy (stimulants/nonstimulants) and behavioral therapy. The primary endpoint was change in Retrospective-Modified Overt Aggression Scale (R-MOAS) score at end of study, with safety monitored. Results: A total of 95 (78.5%) children completed the study. Aggression (R-MOAS) improved with low and medium doses (low dose: p =.031; medium dose: p =.024; high dose: p =.740). The most common adverse events were headache (10.0%), sedation (8.9%), and increased appetite (7.8%). Conclusion: These results suggest SPN-810 may be effective in reducing residual IA behaviors in children with ADHD. Research is still needed to support the benefit–risk profile of SPN-810 in pediatric populations. [ABSTRACT FROM AUTHOR]

Published
2021
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10. Application of the Impulsive Aggression Diary in Adolescents with Attention-Deficit/Hyperactivity Disorder

Author

Ceresoli-Borroni, Gianpiera, primary, Liranso, Tesfaye, additional, Brittain, Scott T., additional, Connor, Daniel F., additional, Evans, Christopher J., additional, Findling, Robert L., additional, Hwang, Steve, additional, Fry, Nicholas, additional, Candler, Shawn A., additional, Robb, Adelaide S., additional, Saylor, Keith E., additional, Nasser, Azmi, additional, and Schwabe, Stefan, additional

Published
2019
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11. A Novel Assessment Tool for Impulsive Aggression in Children with Attention-Deficit/Hyperactivity Disorder

Author

Ceresoli-Borroni, Gianpiera, primary, Liranso, Tesfaye, additional, Brittain, Scott T., additional, Connor, Daniel F., additional, Evans, Christopher J., additional, Findling, Robert L., additional, Hwang, Steve, additional, Candler, Shawn A., additional, Robb, Adelaide S., additional, Nasser, Azmi, additional, and Schwabe, Stefan, additional

Published
2019
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13. Closing the gap: unmet needs of individuals with impulsive aggressive behavior observed in children and adolescents

Author

Robb, Adelaide S., Connor, Daniel F., Amann, Birgit H., Vitiello, Benedetto, Nasser, Azmi, O’Neal, Welton, Schwabe, Stefan, Ceresoli-Borroni, Gianpiera, Newcorn, Jeffrey H., Candler, Shawn A., Buitelaar, Jan K., and Findling, Robert L.

Abstract

AbstractImpulsive aggressive (IA, or impulsive aggression) behavior describes an aggregate set of maladaptive, aggressive behaviors occurring across multiple neuropsychiatric disorders. IA is reactive, eruptive, sudden, and unplanned; it provides information about the severity, but not the nature, of its associated primary disorder. IA in children and adolescents is of serious clinical concern for patients, families, and physicians, given the detrimental impact pediatric IA can have on development. Currently, the ability to properly identify, monitor, and treat IA behavior across clinical populations is hindered by two major roadblocks: (1) the lack of an assessment tool designed for and sensitive to the set of behaviors comprising IA, and (2) the absence of a treatment indicated for IA symptomatology. In this review, we discuss the clinical gaps in the approach to monitoring and treating IA behavior, and highlight emerging solutions that may improve clinical outcomes in patients with IA.

Published
2021
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