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Most studies assessing interreader agreement of Prostate Imaging Reporting and Data System v. 2 (PI-RADS v2) have used biopsy as the standard of reference, thus carrying the risk of not definitively noting all existent cancers.To evaluate the interreader agreement in assessing prostate cancer (PCa) of PI-RADS v2, using whole-mount histology as the standard of reference.Monocentric prospective cohort study.In all, 48 patients with biopsy-proven PCa referred for radical prostatectomy, undergoing staging multiparametric magnetic resonance imaging (mpMRI) between May 2016 to February 2017.3.0T system using high-resolution TCohen's kappa analysis of agreement.On 71 lesions found on histology, there was moderate agreement in assigning PI-RADS categories to all cancers (k = 0.53) and clinically significant cancers (csPCa) (k = 0.47). Assessing csPCa with PI-RADS ≥4 cutoff provided higher agreement than PI-RADS ≥3 cutoff (k = 0.63 vs. 0.57). Interreader agreement was higher between more experienced readers, with the most experienced one achieving the highest cancer detection rate (0.73 for csPCa using category ≥4). There was substantial agreement in assessing stage ≥pT3 (k = 0.72).We found moderate to substantial agreement in assigning the PI-RADS v2 categories and assessing the spectrum of cancers found on whole-mount histology, with category 4 as the most reproducible cutoff for csPCa. Readers' experience influenced interreader agreement and cancer detection rate.2 Technical Efficacy: Stage 2 J. Magn. Reson. Imaging 2019;49:546-555.

Aims and objectives Methods and materials Results Conclusion Personal information References, Aims and objectives: Background DTI Diffusion Tensor Imaging (DTI) is a variant of Diffusion-weighted Imaging (DWI) in which motion probing gradients are applied along multiple space directions in order to build a “tensor”, i.e. a matrix of translational motions of...

Aims and objectives Methods and materials Results Conclusion Personal information References, Aims and objectives: Background DTI Diffusion Tensor Imaging (DTI) is a variant of Diffusion-weighted Imaging (DWI) in which motion probing gradients are applied along multiple space directions in order to build a “tensor”, i.e. a matrix of translational motions of...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Diagnostic confidence (DC) The DC underlying medical decisions has a pivotal impact on patient management [1]. Moreover, quantifying the effect that a diagnostic test has on DC serves as an assessment of the efficacy of that test [2-3]. A number of...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Background The added value of Diffusion-weighted Imaging (DWI) in characterizing focal liver lesions (FLLs) is under debate. Most studies on DWI [1] are focused on comparing benign and malignant FLLs in terms of ADC quantification...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Background The added value of Diffusion-weighted Imaging (DWI) in characterizing focal liver lesions (FLLs) is under debate. Diagnostic accuracy for malignancy widely varies in different studies [1], depending on lesion histology or technical...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Background Over the last years, Diffusion-weighted Imaging (DWI) has been largely investigated as a tool to provide noninvasive detection [1] and quantification of liver fibrosis [2-3]. Fibrosis results from the accumulation of extracellular matrix...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Background Multidetector-row Computed Tomography (MDCT), is a rapidly evolving technology suited for high demanding diagnostic skills, especially in cardiovascular and body imaging [1]. Because of the extremely rapid scan speed inherent to...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: Pulmonary Embolism (PE) is the third most common acute cardiovascular disease and a frequent cause for acute hospital admission, with a reported associated mortality rate exceeding 15% in the first 3 months after the diagnosis [1,2]. In clinical...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: BACKGROUND AND PURPOSES The clinical problem Biliary strictures represent one of the most frequent biliary complications after OLT, showing a rate of occurrence around 2-14% [1]. Diagnosis of biliary strictures may be difficult, since their clinical...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: To date, Endoscopic Retrograde Cholangiopancreatography (ERCP) still remains the standard of reference among different imaging techniques investigating biliary and pancreatic pathologies [1, 2]. In recent years, imaging techniques alternative to...

Learning objectives Background Imaging findings OR Procedure details Conclusion Personal Information References, Learning objectives: To illustrate the rationale, the technical issues and the current clinical application of breast Diffusion-Weighted Imaging (DWI). To describe technical and clinical challenges of breast DWI at...

Purpose Methods and Materials Results Conclusion References Personal Information, Purpose: BACKGROUND The clinical problem PCs have been traditionally considered a rare finding. Nevertheless, ever-increasing application and technical improvements in imaging technology are expected to increase the frequency of incidentally discovered...