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392 results on '"Cennamo V."'

1. OC.17.4: TECHNICAL FAILURE DURING COLORECTAL ENDOSCOPIC FULL THICKNESS RESECTION: THE “THROUGH THICK AND THIN” STUDY

Author

Gibiino, G., primary, Binda, C., additional, Papparella, L.G., additional, Spada, C., additional, Andrisani, G., additional, Di Matteo, F.M., additional, Gagliardi, M., additional, Maurano, A., additional, Sferrazza, S., additional, Azzolini, F., additional, Grande, G., additional, De Nucci, G., additional, Cesaro, P., additional, Aragona, G., additional, Cennamo, V., additional, Fusaroli, P., additional, Staiano, T., additional, Soriani, P., additional, Campanale, M.C., additional, Di Mitri, R., additional, Pugliese, F., additional, Anderloni, A., additional, Cucchetti, A., additional, Repici, A., additional, and Fabbri, C., additional

Published
2024
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2. Diagnostic Accuracy of Different Cholangioscopy-Guided Biopsy Techniques for the Diagnosis of Indeterminate Biliary Duct Strictures

Author

de Jong, D. M., additional, De Jonge, P.J. F., additional, Stassen, P.M. C., additional, Karagyozov, P., additional, Vila, J. J., additional, Fernandez-Urien, I., additional, James, M. W., additional, Venkatachalapathy, S. Vasan, additional, Oppong, K., additional, Anderloni, A., additional, Repici, A., additional, Gabbiadini, R., additional, Joshi, D., additional, Ellrichmann, M., additional, Kylänpää, M. L., additional, Udd, M., additional, Van Der Heide, F., additional, Hindryckx, P., additional, Corbett, G., additional, Basiliya, K., additional, Cennamo, V., additional, Landi, S., additional, Phillpotts, S., additional, Webster, G., additional, and Bruno, M. J., additional

Published
2024
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6. Regret affects the choice between neoadjuvant therapy and upfront surgery for potentially resectable pancreatic cancer

Author

Cucchetti, A., Djulbegovic, B., Crippa, S., Hozo, I., Sbrancia, M., Tsalatsanis, A., Binda, C., Fabbri, C., Salvia, R., Falconi, M., Ercolani, G., Alfieri, Sergio, Amato, A., Amisano, M., Anderloni, A., Maestri, A., Coluccio, C., Brandi, G., Casadei-Gardini, A., Cennamo, V., Crino, S. F., Valle, R. D., De Angelis, C., Di Battista, M., Di Maio, M., Di Marco, M., Di Matteo, F., Di Mitri, R., Ettorre, G. M., Facciorusso, A., Farina, G., Ferrari, G., Fornaro, L., Frigerio, I., Frisone, D., Fuccio, L., Gardini, A., Garufi, C., Giampieri, R., Grazi, G. L., Jovine, E., Kauffmann, E., Langella, S., Larghi, Alberto Leonardo, Manno, M., Marciano, E., Marzioni, M., Merighi, A., Mutignani, M., Nardo, B., Niger, M., Palmisano, V., Partelli, S., Pinto, C., Piras, E., Rapposelli, I. G., Reni, M., Ricci, C., Rimassa, L., Siena, S., Spada, Cristiano, Sperti, E., Spezzaferro, M., Sposito, C., Tamberi, S., Troisi, R., Veneroni, L., Vivarelli, M., Zerbi, A., Alfieri S. (ORCID:0000-0002-0404-724X), Larghi A., Spada C. (ORCID:0000-0002-5692-0960), Cucchetti, A., Djulbegovic, B., Crippa, S., Hozo, I., Sbrancia, M., Tsalatsanis, A., Binda, C., Fabbri, C., Salvia, R., Falconi, M., Ercolani, G., Alfieri, Sergio, Amato, A., Amisano, M., Anderloni, A., Maestri, A., Coluccio, C., Brandi, G., Casadei-Gardini, A., Cennamo, V., Crino, S. F., Valle, R. D., De Angelis, C., Di Battista, M., Di Maio, M., Di Marco, M., Di Matteo, F., Di Mitri, R., Ettorre, G. M., Facciorusso, A., Farina, G., Ferrari, G., Fornaro, L., Frigerio, I., Frisone, D., Fuccio, L., Gardini, A., Garufi, C., Giampieri, R., Grazi, G. L., Jovine, E., Kauffmann, E., Langella, S., Larghi, Alberto Leonardo, Manno, M., Marciano, E., Marzioni, M., Merighi, A., Mutignani, M., Nardo, B., Niger, M., Palmisano, V., Partelli, S., Pinto, C., Piras, E., Rapposelli, I. G., Reni, M., Ricci, C., Rimassa, L., Siena, S., Spada, Cristiano, Sperti, E., Spezzaferro, M., Sposito, C., Tamberi, S., Troisi, R., Veneroni, L., Vivarelli, M., Zerbi, A., Alfieri S. (ORCID:0000-0002-0404-724X), Larghi A., and Spada C. (ORCID:0000-0002-5692-0960)

Abstract

Background: When treating potentially resectable pancreatic adenocarcinoma, therapeutic decisions are left to the sensibility of treating clinicians who, faced with a decision that post hoc can be proven wrong, may feel a sense of regret that they want to avoid. A regret-based decision model was applied to evaluate attitudes to-ward neoadjuvant therapy versus upfront surgery for potentially resectable pancreatic adenocarcinoma.Methods: Three clinical scenarios describing high-, intermediate-, and low-risk disease-specific mortality after upfront surgery were presented to 60 respondents (20 oncologists, 20 gastroenterologists, and 20 surgeons). Respondents were asked to report their regret of omission and commission regarding neo-adjuvant chemotherapy on a scale between 0 (no regret) and 100 (maximum regret). The threshold model and a multilevel mixed regression were applied to analyze respondents' attitudes toward neo-adjuvant therapy.Results: The lowest regret of omission was elicited in the low-risk scenario, and the highest regret in the high-risk scenario (P < .001). The regret of the commission was diametrically opposite to the regret of omission (P < .001). The disease-specific threshold mortality at which upfront surgery is favored over the neoadjuvant therapy progressively decreased from the low-risk to the high-risk scenarios (P <=.001). The nonsurgeons working in or with lower surgical volume centers (P = .010) and surgeons (P = .018) accepted higher disease-specific mortality after upfront surgery, which resulted in the lower likelihood of adopting neoadjuvant therapy.Conclusion: Regret drives decision making in the management of pancreatic adenocarcinoma. Being a surgeon or a specialist working in surgical centers with lower patient volumes reduces the likelihood of recommending neoadjuvant therapy.(c) 2023 Elsevier Inc. All rights reserved.

Published
2023

7. Technical failure during Colorectal Endoscopic Full Thickness Resection (EFTR): The “through thick and thin” Study

Author

Gibiino, G., additional, Binda, C., additional, Papparella, L. G., additional, Petruzziello, L., additional, Gagliardi, M., additional, Maurano, A., additional, Sferrazza, S., additional, Azzolini, F., additional, Grande, G., additional, De Nucci, G., additional, Cesaro, P., additional, Aragona, G., additional, Cennamo, V., additional, Fusaroli, P., additional, Staiano, T., additional, Manno, M., additional, Campanale, M. C., additional, Anderloni, A., additional, Sbrancia, M., additional, Coluccio, C., additional, Cucchetti, A., additional, Repici, A., additional, and Fabbri, C., additional

Published
2023
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8. Results of a multicentric survey on the availability and use of anesthesiologist-directed care in gastrointestinal endoscopy

Author

Biancheri, P., additional, Bonura, G. F., additional, Soriani, P., additional, Pileggi, R., additional, Aragona, G., additional, Cennamo, V., additional, Colecchia, A., additional, Conigliaro, R., additional, Di Marco, M., additional, Fabbri, C., additional, Fuccio, L., additional, Fusaroli, P., additional, Merighi, A., additional, Mussetto, A., additional, Nervi, G., additional, Orsi, P., additional, Sassatelli, R., additional, Zagari, R. M., additional, and Manno, M., additional

Published
2023
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11. T.04.8 A MULTICENTRIC SURVEY ON THE AVAILABILITY AND USE OF ANESTHESIOLOGIST-DIRECTED CARE IN GASTROINTESTINAL ENDOSCOPY

Author

Bonura, G.F., primary, Biancheri, P., additional, Soriani, P., additional, Pileggi, R., additional, Aragona, G., additional, Cennamo, V., additional, Colecchia, A., additional, Conigliaro, R., additional, Di Marco, M., additional, Fabbri, C., additional, Fuccio, L., additional, Fusaroli, P., additional, Merighi, A., additional, Mussetto, A., additional, Nervi, G., additional, Orsi, P., additional, Sassatelli, R., additional, Zagari, M., additional, and Manno, M., additional

Published
2023
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15. OC.09.5 REPEATED EUS-GUIDED FINE NEEDLE BIOPSY OF PANCREATIC MASSES AFTER NON-DIAGNOSTIC OR INCONCLUSIVE RESULTS – THE REUBIO STUDY

Author

Cominardi, A., primary, Lisotti, A., additional, Crinò, S.F., additional, Larghi, A., additional, Facciorusso, A., additional, Arcidiacono, P.G., additional, Fabbri, C., additional, Bertani, H., additional, De Angelis, C., additional, Di Matteo, F.M., additional, Pisani, A., additional, Brancaccio, M.L., additional, Dabizzi, E., additional, Grillo, A., additional, Fantin, A., additional, Pezzoli, A., additional, Decembrino, F., additional, Amato, A., additional, Togliani, T., additional, Antonini, F., additional, Montale, A., additional, Forti, E., additional, Cennamo, V., additional, Manno, M., additional, Carrara, S., additional, Mangiavillano, B., additional, Zaccari, P., additional, Binda, C., additional, Aragona, G., additional, Mussetto, A., additional, Conti Bellocchi, M.C., additional, Stigliano, S., additional, Gasparini, E., additional, Rizzatti, G., additional, Pellegrino, M.G., additional, Muscatiello, N., additional, Marocchi, G., additional, Mangiafico, S., additional, Lupo, M., additional, Burattini, O., additional, Lovero, R., additional, Fabbri, S., additional, Dall’Amico, E., additional, D’Errico, F., additional, Gabbani, T., additional, Petrone, M.C., additional, Zagari, R.M., additional, and Fusaroli, P., additional

Published
2022
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16. REPEATED EUS-GUIDED FINE NEEDLE BIOPSY AFTER NON-DIAGNOSTIC OR INCONCLUSIVE RESULTS OF SOLID PANCREATIC MASSES – THE REUBIO STUDY

Author

Cominardi, A., additional, Lisotti, A., additional, Crinò, S.F., additional, Larghi, A., additional, Facciorusso, A., additional, Fabbri, C., additional, Bertani, H., additional, De Angelis, C., additional, Di Matteo, F.M., additional, Pisani, A., additional, Brancaccio, M.L., additional, Dabizzi, E., additional, Grillo, A., additional, Fantin, A., additional, Pezzoli, A., additional, Decembrino, F., additional, Amato, A., additional, Togliani, T., additional, Antonini, F., additional, Montale, A., additional, Forti, E., additional, Cennamo, V., additional, Manno, M., additional, Carrara, S., additional, Arcidiacono, P.G., additional, Mangiavillano, B., additional, Binda, C., additional, Aragona, G., additional, Mussetto, A., additional, Conti Bellocchi, M.C., additional, Stigliano, S., additional, Gasparini, E., additional, Rizzatti, G., additional, Pellegrino, M.G., additional, Muscatiello, N., additional, Marocchi, G., additional, Mangiafico, S., additional, Lupo, M., additional, Burattini, O., additional, Lovero, R., additional, Fabbri, S., additional, Dall'Amico, E., additional, D'Errico, F., additional, Gabbani, T., additional, Zagari, R.M., additional, and Fusaroli, P., additional

Published
2022
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19. The management of endoscopic retrograde cholangiopancreatography-related infections risk: results of an italian survey at regional level.

Author

Cennamo, V., Landi, S., Aragona, G., Colecchia, A., Conigliaro, R., Di Lorenzo, D., Di Marco, M., Fabbri, C., Falcone, P., Gaiani, F., Manno, M., Merighi, A., Mussetto, A., Peghetti, A., Sassateli, R., Solfrini, V., Zagari, R. M., Arena, R., Bertani, H., and Binda, C.

Subjects
ENDOSCOPIC retrograde cholangiopancreatography, MULTIDRUG resistance, IMMUNOSUPPRESSIVE agents, INTERNET surveys, CLINICAL trials
Abstract

Copyright of Annali di Igiene, Medicina Preventiva e di Comunità is the property of Societa Editrice Universo s.r.l. and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

Published
2023
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23. T01.01.5 THE GASTROPACK SYSTEM AS A MODEL FOR EGD APPROPRIATENESS IN PATIENTS WITH UPPER GASTROINTESTINAL SYMPTOMS: A COMPARISON WITH THE OPEN ACCESS SYSTEM

Author

Ceroni, L., primary, Lodato, F., additional, Fabbri, C., additional, Tubertini, P., additional, Biselli, M., additional, Gramenzi, A., additional, Migliano, M.T., additional, Ferrara, F., additional, Buonfiglioli, F., additional, Schiumerini, R., additional, Polifemo, A.M., additional, Alberani, A., additional, Gazzola, A., additional, and Cennamo, V., additional

Published
2020
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28. THE GASTROPACK SYSTEM AS A MODEL FOR EGD APPROPRIATENESS IN PATIENTS WITH UPPER GASTROINTESTINAL SYMPTOMS: A COMPARISON WITH THE OPEN ACCESS SYSTEM

Author

Ceroni, L, additional, Lodato, F, additional, Fabbri, C, additional, Tubertini, P, additional, Biselli, M, additional, Gramenzi, A, additional, Migliano, MT, additional, Ferrara, F, additional, Buonfiglioli, F, additional, Schiumerini, R, additional, Polifemo, A, additional, Alberani, A, additional, Gazzola, A, additional, and Cennamo, V, additional

Published
2020
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34. Endoscopy units and the COVID-19 Outbreak: A Multi-Center Experience from Italy

Author

Repici, A, Pace, F, Gabbiadini, R, Colombo, M, Hassan, C, Dinelli, M, Maselli, R, Spadaccini, M, Mutignani, M, Gabbrielli, A, Signorelli, C, Spada, C, Leoni, P, Fabbri, C, Segato, S, Gaffuri, N, Mangiavillano, B, Radaelli, F, Salerno, R, Bargiggia, S, Maroni, L, Benedetti, A, Occhipinti, P, De Grazia, F, Ferraris, L, Cengia, G, Greco, S, Alvisi, C, Scarcelli, A, De Luca, L, Cereatti, F, Testoni, Pa, Mingotto, R, Aragona, G, Manes, G, Beretta, P, Amvrosiadis, G, Cennamo, V, Lella, F, Missale, G, Lagoussis, P, Triossi, O, Giovanardi, M, De Roberto, G, Canto, P, Buscarini, E, Anderloni, A, Carrara, S, Fugazza, A, Galtieri, Pa, Pellegatta, G, Antonelli, G, Rosch, T, and Sharma, P

Subjects
Coronavirus, Pandemic, Survery, COVID-19, Endoscopy
Published
2020

36. Endoscopy Units and the Coronavirus Disease 2019 Outbreak: A Multicenter Experience From Italy

Author

Repici, A., Pace, F., Gabbiadini, R., Colombo, M., Hassan, Cesare, Dinelli, M., Maselli, R., Spadaccini, M., Mutignani, Massimiliano, Gabbrielli, A., Signorelli, C., Spada, Cristiano, Leoni, Paola, Fabbri, Carlo, Segato, S., Gaffuri, N., Mangiavillano, B., Radaelli, F., Salerno, R., Bargiggia, S., Maroni, L., Benedetti, A., Occhipinti, P., De Grazia, F., Ferraris, L., Cengia, G., Greco, Sara, Alvisi, C., Scarcelli, A., De Luca, L., Cereatti, F., Testoni, P. A., Mingotto, R., Aragona, G., Manes, G., Beretta, P., Amvrosiadis, G., Cennamo, Vincenzo, Lella, F., Missale, G., Lagoussis, P., Triossi, O., Giovanardi, Mattia, De Roberto, G., Cantu, P., Buscarini, E., Anderloni, A., Carrara, S., Fugazza, A., Galtieri, P. A., Pellegatta, G., Antonelli, G., Rosch, T., Sharma, P., Hassan C., Mutignani M. (ORCID:0000-0002-1272-4888), Spada C. (ORCID:0000-0002-5692-0960), Leoni P., Fabbri C., Greco S., Cennamo V., Giovanardi M., Repici, A., Pace, F., Gabbiadini, R., Colombo, M., Hassan, Cesare, Dinelli, M., Maselli, R., Spadaccini, M., Mutignani, Massimiliano, Gabbrielli, A., Signorelli, C., Spada, Cristiano, Leoni, Paola, Fabbri, Carlo, Segato, S., Gaffuri, N., Mangiavillano, B., Radaelli, F., Salerno, R., Bargiggia, S., Maroni, L., Benedetti, A., Occhipinti, P., De Grazia, F., Ferraris, L., Cengia, G., Greco, Sara, Alvisi, C., Scarcelli, A., De Luca, L., Cereatti, F., Testoni, P. A., Mingotto, R., Aragona, G., Manes, G., Beretta, P., Amvrosiadis, G., Cennamo, Vincenzo, Lella, F., Missale, G., Lagoussis, P., Triossi, O., Giovanardi, Mattia, De Roberto, G., Cantu, P., Buscarini, E., Anderloni, A., Carrara, S., Fugazza, A., Galtieri, P. A., Pellegatta, G., Antonelli, G., Rosch, T., Sharma, P., Hassan C., Mutignani M. (ORCID:0000-0002-1272-4888), Spada C. (ORCID:0000-0002-5692-0960), Leoni P., Fabbri C., Greco S., Cennamo V., and Giovanardi M.

Abstract

Up to 20% of health care personnel (HCP) were found to be infected with coronavirus disease (COVID-19)1 in the outbreak in northern Italy.2 Recommendations on patient and HCP protection have been made, such as postponing procedures, triage, use of personal protective equipment (PPE), and creation of differentiated in-hospital pathways.3,4 However, several barriers against the adoption of these strategies exist, including cultural factors and shortages of medical resources; therefore, there are few reports of real-world experiences and outcomes with their adoption.5 The aim of this survey was to investigate the burden of COVID-19 on endoscopic activity in a high-risk area of COVID-19 outbreak, approaches to evaluating patients, adoption and compliance of HCP with protective measures, and initial possible viral transmission outcomes from endoscopy units within a large, community-based setting (both between patients and HCP and between HCP).

Published
2020

37. Single-step endoscopic ultrasound-guided multiple gateway drainage of complex walled-off necrosis with lumen apposing metal stents

Author

Binda, C., Dabizzi, E., Anderloni, A., Cennamo, Vincenzo, Fiscaletti, M., Fugazza, A., Jovine, E., Ercolani, G., Gasbarrini, Antonio, Fabbri, Maria Cristina, Cennamo V., Gasbarrini A. (ORCID:0000-0002-7278-4823), Fabbri C., Binda, C., Dabizzi, E., Anderloni, A., Cennamo, Vincenzo, Fiscaletti, M., Fugazza, A., Jovine, E., Ercolani, G., Gasbarrini, Antonio, Fabbri, Maria Cristina, Cennamo V., Gasbarrini A. (ORCID:0000-0002-7278-4823), and Fabbri C.

Abstract

In this study we analyzed the feasibility and safety of single-step multiple transluminal gateway drainage (MTGD) for complex walled-off necrosis (WON) using lumen-apposing metal stents (LAMSs). Six patients underwent endoscopic ultrasound (EUS)-guided MTGD using two LAMSs. Technical success was 100%. The mean procedure time was 29 min. The mean number of direct endoscopic necrosectomy sessions per patient was 2. Two of six patients developed adverse events, which was bleeding in both cases and treated endoscopically and surgically, respectively. The mean hospital stay was 52.5 days. No patients had residual necrosis or WON recurrence. Although the limited number of patients, the single-step MTGD using electrocautery-LAMSs can be considered a feasible and well-tolerated treatment option for patients with complex WON. Nevertheless, larger randomized controlled studies are needed in order to confirm our data and better define the advantages of this technique.

Published
2020

38. Defining the biology of intrahepatic cholangiocarcinoma: Molecular pathways and early detection of precursor lesions

Author

Gibiino, G, Fabbri, C, Fagiuoli, S, Ianiro, G, Fornelli, A, Cennamo, V, Gibiino G., Fabbri C., Fagiuoli S., Ianiro G., Fornelli A., Cennamo V., Gibiino, G, Fabbri, C, Fagiuoli, S, Ianiro, G, Fornelli, A, Cennamo, V, Gibiino G., Fabbri C., Fagiuoli S., Ianiro G., Fornelli A., and Cennamo V.

Abstract

Intrahepatic cholangiocarcinoma (ICC) is a rare malignant tumor of the biliary tract with growing incidence and dismal prognosis. It is responsible for 10-20% of primary liver cancer worldwide, but early diagnosis is still a challenge and few treatment options are available. Aim of this review is to summarize the current knowledge about biological features and arising molecular patterns of this disease. The identification of emerging biomarkers and early detection of precursor lesions shall play a key role in the perspective of future tailored targeted therapies.

Published
2017

41. THE GASTROPACK SYSTEM, A NOVEL METHOD TO ACCESS TO GASTROENTEROLOGICAL CARE: RESULTS OF THE UPPER GASTROINTESTINAL SYMPTOM POPULATION

Author

Ceroni, L, additional, Lodato, F, additional, Tubertini, P, additional, Fabbri, C, additional, Buonfiglioli, F, additional, Ferrara, F, additional, Alberani, A, additional, Polifemo, A, additional, Tosetti, C, additional, Lenzi, A, additional, Mondini, S, additional, Veduti, V, additional, and Cennamo, V, additional

Published
2019
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42. HIGH DIAGNOSTIC ADEQUACY AND ACCURACY OF THE NEW 20G PROCORE NEEDLE FOR EUS-GUIDED TISSUE ACQUISITION: RESULTS OF A LARGE MULTICENTRE RETROSPECTIVE STUDY

Author

Fabbri, C, additional, Fornelli, A, additional, Fuccio, L, additional, Giovanelli, S, additional, Tarantino, I, additional, Antonini, F, additional, Liotta, R, additional, Frazzoni, L, additional, Gusella, P, additional, La Marca, M, additional, Barresi, L, additional, Macarri, G, additional, Traina, M, additional, De Biase, D, additional, Fiorino, S, additional, Jovine, E, additional, Larghi, A, additional, and Cennamo, V, additional

Published
2019
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48. Automated evaluation of spatial heterogeneity of extracellular matrix and modeling its degradation in pancreatic ductal adenocarcinoma (PC)

Author

Grizzi, F., primary, Fiorino, S., additional, Patrinicola, F., additional, Fornelli, A., additional, de Biase, D., additional, Masetti, M., additional, Mastrangelo, L., additional, Zanello, M., additional, Lombardi, R., additional, Benini, C., additional, Domanico, A., additional, Accogli, E., additional, Di Saverio, S., additional, Tura, A., additional, Fabbri, C., additional, Giovanelli, S., additional, Cennamo, V., additional, Leandri, P., additional, Di Tommaso, L., additional, and Jovine, E., additional

Published
2019
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49. MANAGEMENT OF RESECTION OF LARGE COLONIC LESIONS IN A REAL-LIFE SETTING: THE SCALP STUDY

Author

Amato, A, additional, Radaelli, F, additional, Cennamo, V, additional, Di Giulio, E, additional, Fuccio, L, additional, Manes, G, additional, Tarantino, O, additional, Fiori, G, additional, De Bellis, M, additional, Buda, A, additional, Pigò, F, additional, Cesaro, P, additional, Occhipinti, P, additional, Feliciangeli, G, additional, Manno, M, additional, Dulbwcco, P, additional, Musso, A, additional, Gullotti, G, additional, Giardini, M, additional, Mangiavillano, B, additional, Paggi, S, additional, Hassan, C, additional, and Repici, A, additional

Published
2018
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50. Actinobacteria: A relevant minority for the maintenance of gut homeostasis

Author

Binda, Cecilia, Lopetuso, Loris Riccardo, Rizzatti, Gianenrico, Gibiino, Giulia, Cennamo, Vincenzo, Gasbarrini, Antonio, Binda C., Lopetuso L. R., Rizzatti G. (ORCID:0000-0003-1876-7587), Gibiino G., Cennamo V., Gasbarrini A. (ORCID:0000-0002-7278-4823), Binda, Cecilia, Lopetuso, Loris Riccardo, Rizzatti, Gianenrico, Gibiino, Giulia, Cennamo, Vincenzo, Gasbarrini, Antonio, Binda C., Lopetuso L. R., Rizzatti G. (ORCID:0000-0003-1876-7587), Gibiino G., Cennamo V., and Gasbarrini A. (ORCID:0000-0002-7278-4823)

Abstract

Actinobacteria are one the four major phyla of the gut microbiota and, although they represent only a small percentage, are pivotal in the maintenance of gut homeostasis. During the last decade many studies focused the attention on Actinobacteria, especially on their role both in gastrointestinal and systemic diseases and on their possible therapeutic use. In fact, classes of this phylum, especially Bifidobacteria, are widely used as probiotic demonstrating beneficial effects in many pathological conditions, even if larger in vivo studies are needed to confirm such encouraging results. This review aims to explore the current knowledge on their physiological functions and to speculate on their possible therapeutic role(s) in gastrointestinal and systemic diseases.

Published
2018

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