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802 results on '"Cennamo, G."'

19. Retinal vascular density in multiple sclerosis: a one year follow up

Author

Lanzillo, R, Cennamo, G, Moccia, M, Criscuolo, C, Carotenuto, A, Frattaruolo, N, Sparnelli, F, MELENZANE, ANTONIETTA, Lamberti, A, Servillo, G, Tranfa, F, De Crecchio, G, Brescia Morra, V, Lanzillo, R, Cennamo, G, Moccia, M, Criscuolo, C, Carotenuto, A, Frattaruolo, N, Sparnelli, F, Melenzane, Antonietta, Lamberti, A, Servillo, G, Tranfa, F, De Crecchio, G, and Brescia Morra, V

Subjects
retina, optical coherence tomography, parafovea, multiple sclerosi, vascular density
Abstract

Vascular pathology is increasingly acknowledged as a risk factor of multiple sclerosis (MS). Vascular density (VD) is reduced in MS patients' eyes on optical coherence tomography (OCT) angiography (A).

Published
2019

20. Clinical features of X linked juvenile retinoschisis associated with new mutations in the XLRS1 gene in Italian families

Author

Simonelli, F, Cennamo, G, Ziviello, C, Testa, F, de Crecchio, G, Nesti, A, Manitto, MP, Ciccodicola, A, Banfi, S, Brancato, R, and Rinaldi, E

Subjects
Retinal diseases -- Research, Health, Research
Abstract

Aims: To describe the clinical phenotype of X linked juvenile retinoschisis in eight Italian families with six different mutations in the XLRS1 gene. Methods: Complete ophthalmic examinations, electroretinography and A [...]

Published
2003

21. Correlation between various trace elements and ultramicroscopic structure of epiretinal macular membranes and glial cells

Author

Romano MR, Cennamo G, Montorio D, Del Prete S, Ferrara M, Cennamo G., CENNAMO, GILDA, Romano, Mr, Cennamo, G, Montorio, D, Del Prete, S, Ferrara, M, Cennamo, G., and Cennamo, Gilda

Subjects
Male, Pathology, genetic structures, medicine.medical_treatment, lcsh:Medicine, Vitrectomy, Mineral composition, Spectrum analysis techniques, Diagnostic Radiology, chemistry.chemical_compound, 0302 clinical medicine, Medicine and Health Sciences, Electron Microscopy, Prospective Studies, lcsh:Science, Tomography, Microscopy, Multidisciplinary, Chemistry, Radiology and Imaging, Phosphorus, Epiretinal Membrane, Middle Aged, Zinc, Membrane, medicine.anatomical_structure, Physical Sciences, Female, Scanning Electron Microscopy, Tomography, Optical Coherence, Research Article, Chemical Elements, Pars plana, medicine.medical_specialty, Imaging Techniques, Iron, Research and Analysis Methods, 03 medical and health sciences, stomatognathic system, Diagnostic Medicine, medicine, Humans, Energy dispersive X-ray spectroscopy, Aged, Glial activation, Diabetic Retinopathy, Biochemistry, Genetics and Molecular Biology (all), Spectrum Analysis, Sodium, lcsh:R, Electron beam spectrum analysis techniques, Retinal, biochemical phenomena, metabolism, and nutrition, Trace Elements, Agricultural and Biological Sciences (all), Microscopy, Electron, Scanning, 030221 ophthalmology & optometry, Ultrastructure, lcsh:Q, Sulfur, 030217 neurology & neurosurgery
Abstract

INTRODUCTION: Elements such as zinc, iron, copper, sulphur and phosphorus have been identified in retinal layers and implicated in vital retinal functions. Regarding mineral composition of epiretinal membranes (ERMs), literature is lacking. This study aimed to analyze both mineral composition and anatomical ultrastructure of ERMs to clarify the pathophysiology of this disease. METHODS: Twenty ERMs (10 diabetic ERMs and 10 idiopathic ERMs) from 20 patients were harvested during pars plana vitrectomy. Scanning Electron Microscopy (SEM) was used to investigate the anatomical ultrastructure of the peeled ERMs. Mineral composition was analyzed using energy-dispersive spectrometry (EDS). The most frequent elements were evaluated in relation to appearance of ERMs analyzed at SEM and at OCT images. RESULTS: Sulphur was the most frequent element found (in 80% of the samples), followed by sodium (50%) and phosphorus (45%). The presence of these elements was not significantly different between diabetic and idiopathic ERMs (P >0.05). Using SEM we found a folded tissue in all ERMs, except in 4 ERMs, where we observed only a smooth tissue. There was a trend of sodium to be more frequent in ERMs with folded layers at SEM examination. CONCLUSIONS: Several elements were identified in ERMs, and sulphur, sodium and phosphorus were the most frequent ones. This finding may help to understand their role in the physiopatology of epiretinal proliferation and in glial activation.

Published
2018

24. Protease mediated processing of a Cu-induced laccase in Pleurotus ostreatus: a natural approach to improve protein stability1 1This work was supported by grants from the Ministero dell'Università e della Ricerca Scientifica (Progetti di Rilevante Interesse Nazionale grant PRIN 98 and PRIN 2000), and from Consiglio Nazionale delle Ricerche (Progetto Finalizzato Biotecnologie).

Author

Giardina, P., primary, Cennamo, G., additional, Greco, C., additional, Palmieri, G., additional, and Sannia, G., additional

Published
2002
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31. Retinal vascular density in multiple sclerosis: a 1‐year follow‐up

Author

Lanzillo, R., primary, Cennamo, G., additional, Moccia, M., additional, Criscuolo, C., additional, Carotenuto, A., additional, Frattaruolo, N., additional, Sparnelli, F., additional, Melenzane, A., additional, Lamberti, A., additional, Servillo, G., additional, Tranfa, F., additional, De Crecchio, G., additional, and Brescia Morra, V., additional

Published
2018
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43. Reply to Chhablani

Author

Forte, R., Cennamo, G. L., Finelli, M., Farese, E., D'Amico, G., Nicoletti, G., DE CRECCHIO, GIUSEPPE, G. , Cennamo, Forte, R., Cennamo, G. L., Finelli, M., Farese, E., D'Amico, G., Nicoletti, G., DE CRECCHIO, Giuseppe, and Cennamo, G.

Subjects
medicine.medical_specialty, Intravitreal triamcinolone, genetic structures, business.industry, Macular oedema, eye diseases, law.invention, Ophthalmology, Randomized controlled trial, Diabetic macular oedema, law, Correspondence, medicine, sense organs, Macular thickening, Intravitreal bevacizumab, business, After treatment
Abstract

Sir, We thank Dr Chhablani1 for his interest in our article2; we evaluated diffuse diabetic macular oedema and obtained good functional and anatomic results during a follow-up of 12 months after treatment with intravitreal bevacizumab, when compared with the combination of intravitreal triamcinolone and laser photocoagulation. We agree that intravitreal bevacizumab lacks in large randomized controlled trials and could be used in case of gross macular oedema in order to reduce macular thickening, followed by laser photocoagulation. The latter remains indeed the gold standard for diabetic macular oedema.

Published
2010

47. Retinal vascular density in multiple sclerosis: a 1‐year follow‐up.

Author

Lanzillo, R., Cennamo, G., Moccia, M., Criscuolo, C., Carotenuto, A., Frattaruolo, N., Sparnelli, F., Melenzane, A., Lamberti, A., Servillo, G., Tranfa, F., De Crecchio, G., and Brescia Morra, V.

Subjects
*MULTIPLE sclerosis, *OPTICAL coherence tomography, *MULTIPLE sclerosis treatment, *RETINA, *ANGIOGRAPHY, *HEALTH outcome assessment
Abstract

Background and purpose: Vascular pathology is increasingly acknowledged as a risk factor for multiple sclerosis (MS). Vascular density (VD) is reduced in the eyes of patients with MS on optical coherence tomography (OCT) angiography. We performed a 1‐year prospective study to estimate VD variations over time and possible clinical correlates. Methods: A total of 50 patients with MS underwent spectral domain‐OCT and OCT angiography at baseline and after 1‐year follow‐up. Mixed‐effect linear regression models were used to assess variations of each OCT measure and its relation to treatment and clinical outcomes. Results: We observed an increase in parafovea VD (coefficient, 1.147; 95% confidence interval, 0.081–2.214; P = 0.035). Reduction in parafovea VD was associated with increase in Expanded Disability Status Scale score (coefficient, −0.969; 95% confidence interval, −1.732/−0.207; P = 0.013). Conclusions: Retinal VD can improve over time in MS, particularly in patients experiencing disease stability. Longer follow‐up, inclusion of early MS cases and combination with conventional markers of MS severity (i.e. brain atrophy) are needed to better define VD as a potential new biomarker. [ABSTRACT FROM AUTHOR]

Published
2019
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49. ledronic acid in the treatment of bone metastases by hepatocellular carcinoma: a case series

Author

Montella L, Addeo R, Caraglia M, Cennamo G, Vincenzi B, Guarrasi R, Mamone R, Faiola V, Frega N, Capasso E, Maiorino L, Leopardo D, Pizza C, Montesarchio V, Del Prete S., PALMIERI, GIOVANNELLA, Montella, L, Addeo, R, Palmieri, Giovannella, Caraglia, M, Cennamo, G, Vincenzi, B, Guarrasi, R, Mamone, R, Faiola, V, Frega, N, Capasso, E, Maiorino, L, Leopardo, D, Pizza, C, Montesarchio, V, and Del Prete, S.

Subjects
ledronic acid, hepatocellular carcinoma, bone metastase
Published
2009

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