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Irène Némirovsky’s novella Les Mouches d’automne (1931. Snow in Autumn, 2007) paints an effective portrait of exile, of the longing for the lost home, and the disorientation that one feels when faced with a reality that is neither recognizable nor understandable. In this article, I analyse Némirovsky’s narrative strategies in relation to spatio-temporal phenomena. My analysis is based on the work of philosophers Mikhail Bakhtin and Gilles Deleuze: Bakhtin’s chronotope and Deleuze’s crystal-image illuminate how the novella’s dominant themes, exile and nostalgia for the home, are irreducible to the clichés of a linear narration and to the simplistic dichotomy home/exile, past/present, and here/there. Instead, Némirovsky creates a productive tension of overlapping and coalescing space- and time-frames. The philosophical framework provided by Bakhtin and Deleuze is useful to unlock and make visible how this thematic complexity is reflected in the novella’s narrative structure. Indeed, my analysis of Les Mouches’s chronotopes and crystal images illuminates Némirovsky’s innovative experimentation in the creation of time–space crossings and a/synchronies, and also contributes to extend further our understanding of Némirovsky’s place within the contemporaneous literary panorama.

HSP90B1 is a gene that codifies heat shock protein 108 (HSP108) that belongs to a group of proteins induced under stress situation, and it has close relation with the nervous system, especially in the retina. Toxoplasma gondii causes ocular toxoplasmosis that has been associated with a late manifestation of the congenital toxoplasmosis although experimental models show that morphological alterations are already present during embryological development. Here, we used 18 eyes of Gallus domesticus embryos in 7th and 20th embryonic days to establish a model of congenital ocular toxoplasmosis, experimentally infected in its fifth day correlating with HSP90B1 gene expression. Embryos' eyes were histologically evaluated, and gene expression was performed by real-time polymerase chain reaction (PCR). Our data showed parasite present in the choroid, unusual migration of retinal pigment epithelium, and chorioretinal scars, and a tendency to a lower expression of the HSP90B1 gene upon experimental infection. This is a promising model to better understand T. gondii etiopathogeny.