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196 results on '"Cavigli, Luna"'

1. List of contributors

Author

Abraham, Kayal, primary, Abuelgasim, Eyas, additional, Adam, Sana, additional, Adesida, Michael O., additional, Ahluwalia, Arjun, additional, Ahmed, Iqra, additional, Ahmed, Sennia, additional, Ahsan, Nazifa, additional, Alim, Samina, additional, Anam, Zahra, additional, Aspinall, Alex, additional, Bayatpoor, Yasmin, additional, Beg, Summayah, additional, Butt, Sundas, additional, Cavigli, Luna, additional, Chong, Jun Heng, additional, Chow, Vanessa Jane, additional, Darbi, Elmahdi, additional, Duric, Bea, additional, D’Ascenzi, Flavio, additional, Eltalib, Dania M.N., additional, Evbayekha, Endurance, additional, Haddad, François, additional, Hamadah Al-Assam, Hayder Jalil, additional, Harky, Amer, additional, Henry, Brandon M., additional, Kakar, Sahil, additional, Khashkhusha, Arwa, additional, Kurkulos, Manucios Marios, additional, Lavie, Carl J., additional, Leung, Marco Shiu Tsun, additional, Lippi, Giuseppe, additional, Memon, Noorulain, additional, Merza, Jebrail, additional, Mukherjee, Prerona, additional, Obemaier, Thomas, additional, Patel, Roshni S.K., additional, Pérez-Quilis, Carme, additional, Premkumar, Ganeshkumar, additional, Ragazzoni, Gian Luca, additional, Rajasekar, Tharun, additional, Ramesh, Pranav, additional, Rowe, Clarissa, additional, Roy, Sakshi, additional, Saha, Priyanshu, additional, Sanchis-Gomar, Fabian, additional, Sarodaya, Varun, additional, Savarimuthu, Sugeevan, additional, Sean Sarma, Vedantashankar, additional, Shankar, Meera, additional, Sondh, Rajan Singh, additional, Theologou, Thomas, additional, Vankad, Maariyah, additional, and Zhang, Yi, additional

Published
2024
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2. The role of echocardiography in sports cardiology: An expert opinion statement of the Italian Society of Sports Cardiology (SIC sport)

Author

Cavarretta, Elena, D'Ascenzi, Flavio, Bianco, Massimiliano, Castelletti, Silvia, Cavigli, Luna, Cecchi, Franco, D'Andrea, Antonello, De Luca, Antonio, Di Salvo, Giovanni, Nistri, Stefano, Palamà, Zefferino, Palmieri, Vincenzo, Ricci, Fabrizio, Sinagra, Gianfranco, Zorzi, Alessandro, Biffi, Alessandro, Pelliccia, Antonio, Romano, Silvio, Dello Russo, Antonio, Zeppilli, Paolo, Patrizi, Giampiero, and Sciarra, Luigi

Published
2024
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3. Physical exercise in hypertensive heart disease: From the differential diagnosis to the complementary role of exercise

Author

Pastore, Maria Concetta, Cavigli, Luna, Olivoni, Gabriele, Morrone, Francesco, Amati, Francesca, Imbalzano, Egidio, Rinaldi, Andrea, Liga, Riccardo, Mattioli, Anna Vittoria, Scicchitano, Pietro, Curcio, Antonio, Barillà, Francesco, Ciccarelli, Michele, Maestrini, Viviana, Perrone Filardi, Pasquale, D'Ascenzi, Flavio, and Cameli, Matteo

Published
2024
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13. Reverse Septal Movement: A Step Forward in the Comprehension of the Underlying Causes

Author

Diviggiano, Enrico Emilio, primary, Rosi, Sara, additional, Landra, Federico, additional, Marallo, Carmine, additional, Scoppa, Cristina, additional, Castellani, Debora, additional, Mandoli, Giulia Elena, additional, Pastore, Maria Concetta, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Cameli, Matteo, additional, and Focardi, Marta, additional

Published
2024
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15. Electrical and structural remodelling in female athlete's heart: A comparative study in women vs men athletes and controls

Author

D'Ascenzi, Flavio, primary, Cavigli, Luna, additional, Marchese, Andrea, additional, Taddeucci, Simone, additional, Cappelli, Elena, additional, Roselli, Alessandra, additional, Bastone, Giuseppe, additional, Lemme, Erika, additional, Serdoz, Andrea, additional, Maestrini, Viviana, additional, Squeo, Maria Rosaria, additional, and Pelliccia, Antonio, additional

Published
2024
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18. Left ventricular fibrosis as a main determinant of filling pressures and left atrial function in advanced heart failure.

Author

Mandoli, Giulia Elena, Cameli, Matteo, Pastore, Maria Concetta, Loiacono, Ferdinando, Righini, Francesca Maria, D'Ascenzi, Flavio, Focardi, Marta, Cavigli, Luna, Lisi, Matteo, Bisleri, Gianluigi, Dokollari, Aleksander, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, and Henein, Michael Y

Subjects
HEART disease diagnosis, HEART failure risk factors, RISK assessment, BIOPSY, HEART atrium, VENTRICULAR ejection fraction, PULMONARY artery, DESCRIPTIVE statistics, FIBROSIS, CARDIAC output, ELECTROCARDIOGRAPHY, HEART transplantation, COMPARATIVE studies, BLOOD pressure, CONFIDENCE intervals, PATIENT satisfaction, LEFT ventricular dysfunction, HEART ventricles, BIOMARKERS, CARDIAC catheterization, DISEASE complications
Abstract

Aims Advanced heart failure (AdHF) is characterized by variable degrees of left ventricular (LV) dysfunction, myocardial fibrosis, and raised filling pressures which lead to left atrial (LA) dilatation and cavity dysfunction. This study investigated the relationship between LA peak atrial longitudinal strain (PALS), assessed by speckle-tracking echocardiography (STE), and invasive measures of LV filling pressures and fibrosis in a group of AdHF patients undergoing heart transplantation (HTX). Methods and results We consecutively enrolled patients with AdHF who underwent HTX at our Department. Demographic and basic echocardiographic data were registered, then invasive intracardiac pressures were obtained from right heart catheterization, and STE was also performed. After HTX, biopsy specimens from explanted hearts were collected to quantify the degree of LV myocardial fibrosis. Sixty-four patients were included in the study (mean age 62.5 ± 11 years, 42% female). The mean LV ejection fraction (LVEF) was 26.7 ± 6.1%, global PALS was 9.65 ± 4.5%, and mean pulmonary capillary wedge pressure (PCWP) was 18.8 ± 4.8 mmHg. Seventy-three % of patients proved to have severe LV fibrosis. Global PALS was inversely correlated with PCWP (R = −0.83; P < 0.0001) and with LV fibrosis severity (R = −0.78; P < 0.0001) but did not correlate with LVEF (R = 0.15; P = 0.2). Among echocardiographic indices of LV filling pressures, global PALS proved the strongest [area under the curve 0.955 (95% confidence interval 0.87–0.99)] predictor of raised (>18 mmHg) PCWP. Conclusion In patients with AdHF, reduced global PALS strongly correlated with the invasively assessed LV filling pressure and degree of LV fibrosis. Such relationship could be used as non-invasive indicator for optimum patient stratification for therapeutic strategies. [ABSTRACT FROM AUTHOR]

Published
2024
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19. Left Ventricular Fibrosis as a Main Determinant of Filling Pressures and Left Atrial Function in Advanced Heart Failure

Author

Mandoli, Giulia Elena, primary, Cameli, Matteo, additional, Pastore, Maria Concetta, additional, Loiacono, Ferdinando, additional, Righini, Francesca Maria, additional, D’Ascenzi, Flavio, additional, Focardi, Marta, additional, Cavigli, Luna, additional, Lisi, Matteo, additional, Bisleri, Gianluigi, additional, Dokollari, Aleksander, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Valente, Serafina, additional, and Henein, Michael, additional

Published
2023
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22. Right ventricular myocardial work for the prediction of early right heart failure and long-term mortality after left ventricular assist device implant.

Author

Landra, Federico, Sciaccaluga, Carlotta, Pastore, Maria Concetta, Gallone, Guglielmo, Barilli, Maria, Fusi, Chiara, Focardi, Marta, Cavigli, Luna, D'Ascenzi, Flavio, Natali, Benedetta Maria, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, Cameli, Matteo, and Mandoli, Giulia Elena

Subjects
LEFT heart ventricle surgery, MORTALITY risk factors, HEART failure risk factors, ECHOCARDIOGRAPHY, MYOCARDIUM, RIGHT heart ventricle, HEART assist devices, RETROSPECTIVE studies, RISK assessment, HEART physiology, RECEIVER operating characteristic curves, SENSITIVITY & specificity (Statistics)
Abstract

Aims Right heart failure (RHF) after left ventricular assist device (LVAD) implant is burdened by high morbidity and mortality rates and should be prevented by appropriate patient selection. Adequate right ventricular function is of paramount importance but its assessment is complex and cannot disregard afterload. Myocardial work (MW) is a non-invasive Speckle Tracking Echocardiography-derived method to estimate pressure–volume loops. The aim of this study was to evaluate the performance of right ventricular myocardial work to predict RHF and long-term mortality after LVAD implant. Methods and results Consecutive patients from May 2017 to February 2022 undergoing LVAD implant were retrospectively reviewed. Patients without a useful echocardiographic exam prior to LVAD implant were excluded. MW analysis was performed. The primary endpoints were early RHF (<30 days from LVAD implant) and death at latest available follow-up. We included 23 patients (mean age 64 ± 8 years, 91% men). Median follow-up was 339 days (IQR: 30–1143). Early RHF occurred in six patients (26%). A lower right ventricular global work efficiency [RVGWE, OR 0.86, 95% confidence intervals (CI) 0.76–0.97, P = 0.014] was associated with the occurrence of early RHF. Among MW indices, the performance for early RHF prediction was greatest for RVGWE [area under the curve (AUC) 0.92] and a cut-off of 77% had a 100% sensitivity and 82% specificity. At long-term follow-up, death occurred in 4 of 14 patients (28.6%) in the RVGWE > 77% group and in 6 of 9 patients (66.7%) in the RVGWE < 77% group (HR 0.25, 95% CI 0.07–0.90, P = 0.033). Conclusion RVGWE was a predictor of early RHF after LVAD implant and brought prognostic value in terms of long-term mortality. [ABSTRACT FROM AUTHOR]

Published
2024
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24. Tricuspid Regurgitation Velocity and Mean Pressure Gradient for the Prediction of Pulmonary Hypertension According to the New Hemodynamic Definition

Author

Mandoli, Giulia Elena, primary, Landra, Federico, additional, Chiantini, Benedetta, additional, Sciaccaluga, Carlotta, additional, Pastore, Maria Concetta, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Valente, Serafina, additional, Cameli, Matteo, additional, and Henein, Michael, additional

Published
2023
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25. Right Ventricular Myocardial Work for the Prediction of Early Right Heart Failure and Long-term Mortality After Left Ventricular Assist Device Implant

Author

Landra, Federico, primary, Sciaccaluga, Carlotta, additional, Pastore, Maria Concetta, additional, Gallone, Guglielmo, additional, Barilli, Maria, additional, Fusi, Chiara, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Natali, Benedetta Maria, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Valente, Serafina, additional, Cameli, Matteo, additional, and Mandoli, Giulia Elena, additional

Published
2023
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28. Pressure–strain loops unveil haemodynamics behind mechanical circulatory support systems

Author

Landra, Federico, primary, Mandoli, Giulia Elena, additional, Sciaccaluga, Carlotta, additional, Gallone, Guglielmo, additional, Bruno, Francesco, additional, Fusi, Chiara, additional, Barilli, Maria, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D'Ascenzi, Flavio, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, Cameli, Matteo, additional, and Valente, Serafina, additional

Published
2023
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29. Athlete's Heart: A Cardiovascular Step-By-Step Multimodality Approach

Author

Palermi, Stefano, primary, Cavarretta, Elena, primary, D’Ascenzi, Flavio, primary, Castelletti, Silvia, primary, Ricci, Fabrizio, primary, Vecchiato, Marco, primary, Serio, Alessandro, primary, Cavigli, Luna, primary, Bossone, Eduardo, primary, Limongelli, Giuseppe, primary, Biffi, Alessandro, primary, Monda, Emanuele, primary, La Gerche, Andre, primary, Baggish, Aaron, primary, and D’Andrea, Antonello, primary

Published
2023
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30. ADONHERS (Aged DONor HEart Rescue by Stress Echo) National Protocol: Recipient’s Survival after 10-Year Follow-Up

Author

Mandoli, Giulia Elena, primary, Barilli, Maria, additional, Soviero, Davide, additional, Ghionzoli, Nicolò, additional, Landra, Federico, additional, Maccherini, Massimo, additional, Bernazzali, Sonia, additional, Natali, Benedetta Maria, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Pastore, Maria Concetta, additional, Sciaccaluga, Carlotta, additional, Bombardini, Tonino, additional, Valente, Serafina, additional, and Cameli, Matteo, additional

Published
2023
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31. Tricuspid regurgitation velocity and mean pressure gradient for the prediction of pulmonary hypertension according to the new hemodynamic definition

Author

Mandoli, Giulia Elena, Landra, Federico, Chiantini, Benedetta, Sciaccaluga, Carlotta, Pastore, Maria Concetta, Focardi, Marta, Cavigli, Luna, D’Ascenzi, Flavio, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, Cameli, Matteo, Henein, Michael Y., Mandoli, Giulia Elena, Landra, Federico, Chiantini, Benedetta, Sciaccaluga, Carlotta, Pastore, Maria Concetta, Focardi, Marta, Cavigli, Luna, D’Ascenzi, Flavio, Bernazzali, Sonia, Maccherini, Massimo, Valente, Serafina, Cameli, Matteo, and Henein, Michael Y.

Abstract

Background: The hemodynamic definition of PH has recently been revised with unchanged threshold of peak tricuspid regurgitation velocity (TRV). The aim of this study was to evaluate the predictive accuracy of peak TRV for PH based on the new (>20 mmHg) and the old (>25 mmHg) cut-off value for mean pulmonary artery pressure (mPAP) and to compare it with the mean right ventricular–right atrial (RV–RA) pressure gradient. Methods: Patients with advanced heart failure were screened from 2016 to 2021. The exclusion criteria were absent right heart catheterization (RHC) results, chronic obstructive pulmonary disease, any septal defect, inadequate acoustic window or undetectable TR. The mean RV–RA gradient was calculated from the velocity–time integral of TR. Results: The study included 41 patients; 34 (82.9%) had mPAP > 20 mmHg and 24 (58.5%) had mPAP > 25 mmHg. The AUC for the prediction of PH with mPAP > 20 mmHg was 0.855 for peak TRV and mean RV–RA gradient was 0.811. AUC for the prediction of PH defined as mPAP > 25 mmHg for peak TRV was 0.860 and for mean RV–RA gradient was 0.830. A cutoff value of 2.4 m/s for peak TRV had 65% sensitivity and 100% positive predictive value for predicting PH according to the new definition. Conclusions: Peak TRV performed better than mean RV–RA pressure gradient in predicting PH irrespective of hemodynamic definitions. Peak TRV performed similarly with the two definitions of PH, but a lower cutoff value had higher sensitivity and equal positive predictive value for PH.

Published
2023
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33. Sports cardiology: A glorious past, a well‐defined present, a bright future.

Author

D'Ascenzi, Flavio, Ragazzoni, Gian L., Boncompagni, Alex, and Cavigli, Luna

Subjects
MEDICAL students, SPORTS injuries, CARDIAC arrest, CARDIOLOGY, MEDICAL education, PROFESSIONAL sports
Abstract

The attention towards sports cardiology has dramatically grown after the introduction of preparticipation screening and the need for specific education on electrocardiogram interpretation in athletes, given the differences between athletes and the general population. The present article stresses the need for specific skills, knowledge, and clinical expertise in sports cardiology, which are essential for appropriately screening competitive athletes to prevent sudden cardiac death and avoid overdiagnosis. However, disqualification from sports competitions may lead to sports inactivity, and athletes may enter a gray zone where little or no information is provided about what they can or cannot do to stay active. However, modern sports cardiology cannot neglect the patient's needs and the importance of the safe practice of regular exercise. In this context, the personalized exercise prescription plays a crucial role in the core curriculum and the clinical activity of professionals involved in sports cardiology programs. Given its specificities, sports cardiology requires a formal education plan for medical school students and all residents. Additional education and practice are required for young colleagues who want to focus their professional lives on sports cardiology. The future directions of emerging modern sports cardiology should not neglect the importance of a scientific community that works together, designing multicenter international outcomes‐based research to address the many remaining areas of uncertainty. [ABSTRACT FROM AUTHOR]

Published
2023
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34. Post-Acute Sequelae of COVID-19: The Potential Role of Exercise Therapy in Treating Patients and Athletes Returning to Play

Author

Cavigli, Luna, primary, Fusi, Chiara, additional, Focardi, Marta, additional, Mandoli, Giulia Elena, additional, Pastore, Maria Concetta, additional, Cameli, Matteo, additional, Valente, Serafina, additional, Zorzi, Alessandro, additional, Bonifazi, Marco, additional, D’Andrea, Antonello, additional, and D’Ascenzi, Flavio, additional

Published
2022
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36. 796 LEFT ATRIAL STRAIN ASSOCIATION WITH FUNCTIONAL CAPACITY IN CARDIAC AMYLOIDOSIS

Author

Pastore, Maria Concetta, primary, Giacomin, Elisa, additional, Marrese, Federica, additional, Ragazzoni, Gian Luca, additional, Mandoli, Giulia Elena, additional, Focardi, Marta, additional, Gozzetti, Alessandro, additional, Cavigli, Luna, additional, Lisi, Matteo, additional, Valente, Serafina, additional, D´ascenzi, Flavio, additional, and Cameli, Matteo, additional

Published
2022
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37. 795 MYOCARDIAL WORK AND LEFT HEART DEFORMATION PARAMETERS ACROSS MITRAL REGURGITATION SEVERITY

Author

Pastore, Maria Concetta, primary, Mandoli, Giulia Elena, additional, Lisi, Matteo, additional, Iuliano, Maria Alma, additional, Paolo Niglio, Francesco, additional, Santoro, Alfonso, additional, Barilli, Maria, additional, Focardi, Marta, additional, Cavigli, Luna, additional, D´ascenzi, Flavio, additional, Valente, Serafina, additional, and Cameli, Matteo, additional

Published
2022
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38. 853 LEFT ATRIAL STRAIN AS A PRGONOSTIC MARKER IN ACUTE AND CHRONIC HEART FAILURE : A META-ANALYSIS AND META-REGRESSION ANALYSIS

Author

Concetta Pastore, Maria, primary, Elena Mandoli, Giulia, additional, Saglietto, Andrea, additional, Stefanini, Andrea, additional, Vigna, Mariangela, additional, Carrucola, Chiara, additional, Fusini, Laura, additional, Cavigli, Luna, additional, D´ascenzi, Flavio, additional, Focardi, Marta, additional, Valente, Serafina, additional, and Cameli, Matteo, additional

Published
2022
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40. Left Atrial Remodeling in Response to Aortic Valve Replacement: Pathophysiology and Myocardial Strain Analysis

Author

Lisi, Matteo, primary, Pastore, Maria Concetta, additional, Fiorio, Alessio, additional, Cameli, Matteo, additional, Mandoli, Giulia Elena, additional, Righini, Francesca Maria, additional, Cavigli, Luna, additional, D’Ascenzi, Flavio, additional, Focardi, Marta, additional, Rubboli, Andrea, additional, Campo, Gianluca, additional, Mondillo, Sergio, additional, and Henein, Michael Y., additional

Published
2022
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41. Left Ventricular Mass with Delayed Enhancement as a Predictor of Major Events in Patients with Myocarditis with Preserved Ejection Fraction

Author

Ghionzoli, Nicolò, primary, Gismondi, Annalaura, additional, Mandoli, Giulia Elena, additional, Spera, Lucia, additional, Di Florio, Alex, additional, D’Ascenzi, Flavio, additional, Cameli, Matteo, additional, Cavigli, Luna, additional, Sciaccaluga, Carlotta, additional, Carbone, Salvatore Francesco, additional, Aquaro, Giovanni Donato, additional, Valente, Serafina, additional, and Focardi, Marta, additional

Published
2022
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43. How to evaluate resting ECG and imaging in children practising sport: a critical review and proposal of an algorithm for ECG interpretation

Author

Ragazzoni, Gian Luca, primary, Cavigli, Luna, additional, Cavarretta, Elena, additional, Maffei, Silvia, additional, Mandoli, Giulia Elena, additional, Pastore, Maria Concetta, additional, Valente, Serafina, additional, Focardi, Marta, additional, Cameli, Matteo, additional, Di Salvo, Giovanni, additional, Pieles, Guido, additional, and D’Ascenzi, Flavio, additional

Published
2022
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44. Left atrial myocardial intrinsic function remodeling response to repair of primary mitral regurgitation

Author

Lisi, Matteo, primary, Cameli, Matteo, additional, Mandoli, Giulia Elena, additional, Pastore, Maria Concetta, additional, Righini, Francesca Maria, additional, Flamigni, Filippo, additional, D'Ascenzi, Flavio, additional, Cavigli, Luna, additional, Focardi, Marta, additional, Rubboli, Andrea, additional, Campo, Gianluca, additional, Mondillo, Sergio, additional, and Henein, Michael Y., additional

Published
2022
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46. A multidisciplinary approach for the emergency care of patients with left ventricular assist devices: A practical guide

Author

Cameli, Matteo, primary, Pastore, Maria Concetta, additional, Mandoli, Giulia Elena, additional, Landra, Federico, additional, Lisi, Matteo, additional, Cavigli, Luna, additional, D'Ascenzi, Flavio, additional, Focardi, Marta, additional, Carrucola, Chiara, additional, Dokollari, Aleksander, additional, Bisleri, Gianluigi, additional, Tsioulpas, Charilaos, additional, Bernazzali, Sonia, additional, Maccherini, Massimo, additional, and Valente, Serafina, additional

Published
2022
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48. Left atrial myocardial intrinsic function remodeling response to repair of primary mitral regurgitation

Author

Lisi, Matteo, Cameli, Matteo, Mandoli, Giulia Elena, Pastore, Maria Concetta, Righini, Francesca Maria, Flamigni, Filippo, D'Ascenzi, Flavio, Cavigli, Luna, Focardi, Marta, Rubboli, Andrea, Campo, Gianluca, Mondillo, Sergio, Henein, Michael Y., Lisi, Matteo, Cameli, Matteo, Mandoli, Giulia Elena, Pastore, Maria Concetta, Righini, Francesca Maria, Flamigni, Filippo, D'Ascenzi, Flavio, Cavigli, Luna, Focardi, Marta, Rubboli, Andrea, Campo, Gianluca, Mondillo, Sergio, and Henein, Michael Y.

Abstract

Severe mitral regurgitation (MR) is a common valve disease which is associated with high mortality, if only managed medically. MR produces chronic and progressive volume overload with left atrial (LA) and left ventricular (LV) dilatation and dysfunction, atrial fibrillation (AF) and eventually myocardial fibrosis, irrespective of ejection fraction (EF). Surgical correction (mitral valve repair) of MR removes the volume overload, hence unmasks pre-operative LV structure and function disturbances, including reduced EF and global longitudinal and circumferential strain, as well as LA volume and strain. This review aims at describing LA remodeling before and after surgical repair.

Published
2022
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49. Left atrial remodeling in response to aortic valve replacement : pathophysiology and myocardial strain analysis

Author

Lisi, Matteo, Pastore, Maria Concetta, Fiorio, Alessio, Cameli, Matteo, Mandoli, Giulia Elena, Righini, Francesca Maria, Cavigli, Luna, D’Ascenzi, Flavio, Focardi, Marta, Rubboli, Andrea, Campo, Gianluca, Mondillo, Sergio, Henein, Michael Y., Lisi, Matteo, Pastore, Maria Concetta, Fiorio, Alessio, Cameli, Matteo, Mandoli, Giulia Elena, Righini, Francesca Maria, Cavigli, Luna, D’Ascenzi, Flavio, Focardi, Marta, Rubboli, Andrea, Campo, Gianluca, Mondillo, Sergio, and Henein, Michael Y.

Abstract

Severe aortic stenosis (AS) is the most common valve disease in the elderly and is associated with poor prognosis if treated only medically. AS causes chronic pressure overload, concentric left ventricular (LV) hypertrophy, myocardial stiffness, and diastolic dysfunction. This adverse remodeling also affects the left atrium (LA), which dilates and develops myocardial fibrosis, with a reduction in intrinsic function and a consequent high risk of the development of atrial fibrillation. Speckle-tracking echocardiography is able to detect myocardial dysfunction before other conventional parameters, such as LV ejection fraction, and also predict clinical outcomes. This review aims at describing LV and LA remodeling in AS and before and after aortic valve replacement and the usefulness of myocardial strain analysis in this clinical setting.

Published
2022
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50. Clinician approach to cardiopulmonary exercise testing for exercise prescription in patients at risk of and with cardiovascular disease

Author

D'Ascenzi, Flavio, primary, Cavigli, Luna, additional, Pagliaro, Antonio, additional, Focardi, Marta, additional, Valente, Serafina, additional, Cameli, Matteo, additional, Mandoli, Giulia Elena, additional, Mueller, Stephan, additional, Dendale, Paul, additional, Piepoli, Massimo, additional, Wilhelm, Matthias, additional, Halle, Martin, additional, Bonifazi, Marco, additional, and Hansen, Dominique, additional

Published
2022
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