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230 results on '"Caversaccio, Marco D."'

8. Two-phase survey on the frequency of use and safety of MRI for hearing implant recipients

Author

van de Heyning, Paul, Mertens, Griet, Topsakal, Vedat, de Brito, Ruben, Wimmer, Wilhelm, Caversaccio, Marco D., Dazert, Stefan, Volkenstein, Stefan, Zernotti, Mario, Parnes, Lorne S., Staecker, Hinrich, Bruce, Iain A., Rajan, Gunesh, Atlas, Marcus, Friedland, Peter, Skarzynski, Piotr H., Sugarova, Serafima, Kuzovkov, Vladislav, Hagr, Abdulrahman, Mlynski, Robert, Schmutzhard, Joachim, Usami, Shin-Ichi, Lassaletta, Luis, Gavilán, Javier, Godey, Benoit, Raine, Christopher H., Hagen, Rudolf, Sprinzl, Georg M., Brown, Kevin, Baumgartner, Wolf-Dieter, and Karltorp, Eva

Published
2021
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16. The value of saccade metrics and VOR gain in detecting a vestibular stroke.

Author

Michailidou, Efterpi, Korda, Athanasia, Wyss, Thomas, Bardins, Stanislav, Schneider, Erich, Morrison, Miranda, Wagner, Franca, Caversaccio, Marco D., and Mantokoudis, Georgios

Subjects
STROKE, CONVENIENCE sampling (Statistics), VESTIBULO-ocular reflex, HOSPITAL emergency services, MEDICAL screening
Abstract

OBJECTIVE: A normal video Head Impulse Test is the gold standard in the emergency department to rule-in patients with an acute vestibular syndrome and a stroke. We aimed to compare the diagnostic accuracy of vHIT metrics regarding the vestibulo-ocular reflex gain and the corrective saccades in detecting vestibular strokes. METHODS: Prospective cross-sectional study (convenience sample) of patients presenting with acute vestibular syndrome in the emergency department of a tertiary referral centre between February 2015 and May 2020. We screened 1677 patients and enrolled 76 patients fulfilling the inclusion criteria of acute vestibular syndrome. All patients underwent video head impulse test with automated and manual data analysis. A delayed MRI served as a gold standard for vestibular stroke confirmation. RESULTS: Out of 76 patients, 52 were diagnosed with acute unilateral vestibulopathy and 24 with vestibular strokes. The overall accuracy of detecting stroke with an automated vestibulo-ocular reflex gain was 86.8%, compared to 77.6% for cumulative saccade amplitude and automatic saccade mean peak velocity measured by an expert and 71% for cumulative saccade amplitude and saccade mean peak velocity measured automatically. Gain misclassified 13.1% of the patients as false positive or false negative, manual cumulative saccade amplitude and saccade mean peak velocity 22.3%, and automated cumulative saccade amplitude and saccade mean peak velocity 28.9% respectively. CONCLUSIONS: We found a better accuracy of video head impulse test for the diagnosis of vestibular strokes when using the vestibulo-ocular reflex gain than using saccade metrics. Nevertheless, saccades provide an additional and important information for video head impulse test evaluation. The automated saccade detection algorithm is not yet perfect compared to expert analysis, but it may become a valuable tool for future non-expert video head impulse test evaluations. [ABSTRACT FROM AUTHOR]

Published
2024
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18. Supplementary Table 1 from Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Author

Nisa, Lluís, primary, Francica, Paola, primary, Giger, Roland, primary, Medo, Matúš, primary, Elicin, Olgun, primary, Friese-Hamim, Manja, primary, Wilm, Claudia, primary, Stroh, Christopher, primary, Bojaxhiu, Beat, primary, Quintin, Aurélie, primary, Caversaccio, Marco D., primary, Dettmer, Matthias S., primary, Buchwalder, Mélanie, primary, Brodie, Tess M., primary, Aebersold, Daniel M., primary, Zimmer, Yitzhak, primary, Carey, Thomas E., primary, and Medová, Michaela, primary

Published
2023
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19. Data from Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Author

Nisa, Lluís, primary, Francica, Paola, primary, Giger, Roland, primary, Medo, Matúš, primary, Elicin, Olgun, primary, Friese-Hamim, Manja, primary, Wilm, Claudia, primary, Stroh, Christopher, primary, Bojaxhiu, Beat, primary, Quintin, Aurélie, primary, Caversaccio, Marco D., primary, Dettmer, Matthias S., primary, Buchwalder, Mélanie, primary, Brodie, Tess M., primary, Aebersold, Daniel M., primary, Zimmer, Yitzhak, primary, Carey, Thomas E., primary, and Medová, Michaela, primary

Published
2023
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20. Supplementary figures 1-6 from Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Author

Nisa, Lluís, primary, Francica, Paola, primary, Giger, Roland, primary, Medo, Matúš, primary, Elicin, Olgun, primary, Friese-Hamim, Manja, primary, Wilm, Claudia, primary, Stroh, Christopher, primary, Bojaxhiu, Beat, primary, Quintin, Aurélie, primary, Caversaccio, Marco D., primary, Dettmer, Matthias S., primary, Buchwalder, Mélanie, primary, Brodie, Tess M., primary, Aebersold, Daniel M., primary, Zimmer, Yitzhak, primary, Carey, Thomas E., primary, and Medová, Michaela, primary

Published
2023
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21. Supplementary Methods from Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Author

Nisa, Lluís, primary, Francica, Paola, primary, Giger, Roland, primary, Medo, Matúš, primary, Elicin, Olgun, primary, Friese-Hamim, Manja, primary, Wilm, Claudia, primary, Stroh, Christopher, primary, Bojaxhiu, Beat, primary, Quintin, Aurélie, primary, Caversaccio, Marco D., primary, Dettmer, Matthias S., primary, Buchwalder, Mélanie, primary, Brodie, Tess M., primary, Aebersold, Daniel M., primary, Zimmer, Yitzhak, primary, Carey, Thomas E., primary, and Medová, Michaela, primary

Published
2023
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22. Supplementary Table 2 from Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Author

Nisa, Lluís, primary, Francica, Paola, primary, Giger, Roland, primary, Medo, Matúš, primary, Elicin, Olgun, primary, Friese-Hamim, Manja, primary, Wilm, Claudia, primary, Stroh, Christopher, primary, Bojaxhiu, Beat, primary, Quintin, Aurélie, primary, Caversaccio, Marco D., primary, Dettmer, Matthias S., primary, Buchwalder, Mélanie, primary, Brodie, Tess M., primary, Aebersold, Daniel M., primary, Zimmer, Yitzhak, primary, Carey, Thomas E., primary, and Medová, Michaela, primary

Published
2023
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23. Measuring the Influence of Magnetic Vestibular Stimulation on Nystagmus, Self-Motion Perception, and Cognitive Performance in a 7T MRT

Author

Wyssen, Gerda, primary, Morrison, Miranda, primary, Korda, Athanasia, primary, Wimmer, Wilhelm, primary, Otero-Millan, Jorge, primary, Ertl, Matthias, primary, Szukics, Andreas A., primary, Wyss, Thomas, primary, Wagner, Franca, primary, Caversaccio, Marco D., primary, Mantokoudis, Georgios, primary, and Mast, Fred W., primary

Published
2023
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28. Videooculography 'HINTS' in Acute Vestibular Syndrome: A Prospective Study

Author

Korda, Athanasia, Wimmer, Wilhelm, Zamaro, Ewa, Wagner, Franca, Sauter, Thomas C, Caversaccio, Marco D, and Mantokoudis, Georgios

Subjects
Neurology, 610 Medicine & health, Neurology (clinical)
Abstract

Objective A three-step bedside test ("HINTS": Head Impulse-Nystagmus-Test of Skew), is a well-established way to differentiate peripheral from central causes in patients with acute vestibular syndrome (AVS). Nowadays, the use of videooculography gives physicians the possibility to quantify all eye movements. The goal of this study is to compare the accuracy of VOG "HINTS" (vHINTS) to an expert evaluation. Methods We performed a prospective study from July 2015 to April 2020 on all patients presenting at the emergency department with signs of AVS. All the patients underwent clinical HINTS (cHINTS) and vHINTS followed by delayed MRI, which served as a gold standard for stroke confirmation. Results We assessed 46 patients with AVS, 35 patients with acute unilateral vestibulopathy, and 11 patients with stroke. The overall accuracy of vHINTS in detecting a central pathology was 94.2% with 100% sensitivity and 88.9% specificity. Experts, however, assessed cHINTS with a lower accuracy of 88.3%, 90.9% sensitivity, and 85.7% specificity. The agreement between clinical and video head impulse tests was good, whereas for nystagmus direction was fair. Conclusions vHINTS proved to be very accurate in detecting strokes in patients AVS, with 9% points better sensitivity than the expert. The evaluation of nystagmus direction was the most difficult part of HINTS.

Published
2022
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30. Multicenter Results with an Active Transcutaneous Bone Conduction Implant in Patients with Single-sided Deafness

Author

Huber, Alexander M, Strauchmann, Bernd, Caversaccio, Marco D, Wimmer, Wilhelm, Linder, Thomas, De Min, Nicola, Hempel, John-Martin, Pollotzek, Marlene, Frenzel, Henning, Hanke, Frauke, Röösli, Christof, Huber, Alexander M, Strauchmann, Bernd, Caversaccio, Marco D, Wimmer, Wilhelm, Linder, Thomas, De Min, Nicola, Hempel, John-Martin, Pollotzek, Marlene, Frenzel, Henning, Hanke, Frauke, and Röösli, Christof

Abstract

Objective: To evaluate the audiological and subjective benefit from hearing rehabilitation with an active bone conduction implant in subjects with single-sided sensorineural deafness (SSD). Study design: Prospective, multicenter, single-subject repeated measures. Setting: Tertiary referral center, five clinics in Germany and Switzerland. Patients: Seventeen subjects aged 18 years and older with severe to profound unilateral sensorineural hearing loss and contralateral normal hearing were followed up for 24 months. Intervention: Active bone conduction implant. Main outcome measures: Speech understanding in noise was assessed in three situations: with signal from front, deaf, or normal hearing side (with noise from front in all set-ups). Subjective benefit was evaluated using the Speech, Spatial, and Qualities of Hearing (SSQ-B) and Bern Benefit in Single-Sided Deafness (BBSS) questionnaire. Results: When the signal was coming from the deaf side the mean improvement of the speech reception threshold in noise ranged from 1.5 up to 2.2 dB with the device and was statistically and clinically significant at all tested timepoints. No significant difference between the aided and unaided situation was found when signal and noise were coming from the front. With the signal from the normal hearing side no clinically significant difference, that is, greater than 1 dB between the aided and unaided situation was found. The SSQ-B and BBSS questionnaire showed an overall improvement with no significant difference between time points. Conclusions: The study demonstrates long-term efficacy and benefit of the device in adults with SSD. Patients reported substantial and persistent subjective benefit from the active bone conduction implant.

Published
2022

38. Sinus floor elevation or referral for further diagnosis and therapy: A comparison of maxillary sinus assessment by ENT specialists and dentists using cone beam computed tomography

Author

Janner, Simone F. M., Dubach, Patrick, Suter, Valérie G. A., Caversaccio, Marco D., Buser, Daniel, and Bornstein, Michael M.

Subjects
otorhinolaryngologic diseases, 610 Medicine & health
Abstract

Objectives: To compare ear, nose, and throat (ENT) specialists and dentists assessing health or pathology of maxillary sinuses using cone beam computed tomography (CBCT). Material and methods: Two ENT specialists and two oral surgeons assessed 100 CBCT datasets of healthy patients referred for dental implant placement in the posterior maxilla and decided on the possibility of sinus floor elevation or the necessity for further diagnostic examinations based solely on radiographic findings. Inter-rater agreements within the same specialty were calculated with Cohen's kappa and overall agreements with Fleiss kappa, and factors influencing the decisions taken were evaluated using regression analyses. Results: The correlation between all four raters was generally fair to moderate. The intra-specialty comparison showed a lower correlation between dentists than between ENT specialists. Absence of membrane thickening and total or subtotal sinus opacification showed the highest predictive value for a consensus in favor of sinus floor elevation and ENT referral, respectively. Flat membrane thickening with an irregular surface morphology was associated with disagreement between the examiners. Dome-shaped membrane thickenings were often considered as to be referred by dentists but not by ENTs. Conclusion: The assessment of maxillary sinuses using CBCT imaging exhibited unsatisfactory agreement between ENT specialists and oral surgeons. Referral guidelines based on accidental CBCT findings that aim to diagnose relevant sinus pathologies early and avoid unnecessary diagnostics and/or therapies are needed, and an initial proposal for such recommendations is provided. Further research on correct interpretation of sinus findings and a validation of the present recommendations are required. K E Y W O R D S cone beam computed tomography, dental implants, ear, nose, and throat, maxillary sinus, sinus floor elevation

Published
2020
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39. Targeting the MET receptor tyrosine kinase as a strategy for radiosensitization in loco-regionally advanced head and neck squamous cell carcinoma

Author

Nisa, Lluís, Francica, Paola, Giger, Roland, Medo, Matúš, Eliçin, Olgun, Friese-Hamim, Manja, Wilm, Claudia, Stroh, Christopher, Bojaxhiu, Beat, Quintin, Aurélie, Caversaccio, Marco D., Dettmer, Matthias S., Buchwalder, Mélanie, Brodie, Tess M., Aebersold, Daniel M., Zimmer, Yitzhak, Carey, Thomas E., and Medova, Michaela

Subjects
570 Life sciences, biology, 610 Medicine & health
Published
2020
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42. Contributor contact details

Author

Gomes, Paula, primary, Vitiello, V., additional, Kwok, K.-W., additional, Yang, G.-Z., additional, Glossop, Neil, additional, Cossetto, Tyler, additional, Zareinia, Kourosh, additional, Sutherland, Garnette R., additional, Zenati, Marco A., additional, Mahvash, Mohsen, additional, Hodgson, Antony, additional, Plaskos, Christopher, additional, Koenig, Jan A., additional, Ponder, Corey E., additional, Bell, Brett, additional, Caversaccio, Marco D., additional, Weber, Stefan, additional, Meenink, H.C.M., additional, Hendrix, R., additional, Naus, G.J.L., additional, Beelen, M.J., additional, Nijmeijer, H., additional, Steinbuch, M., additional, van Oosterhout, E.J.G.M., additional, de Smet, M.D., additional, Reynoso, Jason, additional, Meyer, Avishai, additional, Unnirevi, Jayaraj, additional, Oleynikov, Dmitry, additional, Gorlewicz, Jenna L., additional, Webster, Robert J., additional, Valdastri, Pietro, additional, Belharet, Karim, additional, Folio, David, additional, Ferreira, Antoine, additional, Sharkey, Noel, additional, and Sharkey, Amanda, additional

Published
2012
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45. VOR gain calculation methods in video head impulse recordings

Author

Zamaro, Ewa, primary, Saber Tehrani, Ali S., additional, Kattah, Jorge C., additional, Eibenberger, Karin, additional, Guede, Cynthia I., additional, Armando, Lenz, additional, Caversaccio, Marco D., additional, Newman-Toker, David E., additional, and Mantokoudis, Georgios, additional

Published
2020
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48. Targeting the MET Receptor Tyrosine Kinase as a Strategy for Radiosensitization in Locoregionally Advanced Head and Neck Squamous Cell Carcinoma

Author

Nisa, Lluís, primary, Francica, Paola, additional, Giger, Roland, additional, Medo, Matúš, additional, Elicin, Olgun, additional, Friese-Hamim, Manja, additional, Wilm, Claudia, additional, Stroh, Christopher, additional, Bojaxhiu, Beat, additional, Quintin, Aurélie, additional, Caversaccio, Marco D., additional, Dettmer, Matthias S., additional, Buchwalder, Mélanie, additional, Brodie, Tess M., additional, Aebersold, Daniel M., additional, Zimmer, Yitzhak, additional, Carey, Thomas E., additional, and Medová, Michaela, additional

Published
2020
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