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3. O-02: RADIOMICS AND ARTIFICIAL INTELLIGENCE FOR IDENTIFICATION AND MONITORING OF SILENT CEREBRAL INFARCTS IN SICKLE CELL DISEASE: FIRST ANALYSIS FROM THE GENOMED4ALL EUROPEAN PROJECT

Author

BIONDI R., BOARO M., BIONDINI N., COLLADO GIMBERT A., ESCUDERO FERNANDEZ J., PINTO V., ROMANO N., VOI V., FERRERO G., CASALE M., CIRILLO M., PALAZZI G., CAVALLERI F., FORNI G., REGGIANI G., PERROTTA S., MANU PEREIRA M., ZAZO S., MARIAS K., DE MONTALEMBERT M., BARTOLUCCI P., VANBEERS E., ALVAREZ F., CREMONESI F., SANAVIA T., FARISELLI P., CASTELLANI G., MANARA R., and COLOMBATTI R.

Subjects
Diseases of the blood and blood-forming organs, RC633-647.5
Published
2022
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4. The Prognostic Roles of Gender and O6-Methylguanine-DNA Methyltransferase Methylation Status in Glioblastoma Patients: The Female Power

Author

Baruzzi, A., Albani, F., Calbucci, F., D'Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E., Tosoni, A., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A.M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall'Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall'Agata, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Faedi, M., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A.R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Colella, M., Fallica, E., Farneti, M., Frassoldati, A., Granieri, E., Latini, F., Monetti, C., Saletti, A., Schivalocchi, R., Sarubbo, S., Seraceni, S., Tola, M.R., Urbini, B., Zini, G., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E.M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., Nobile, C., Franceschi, Enrico, Tosoni, Alicia, Minichillo, Santino, Depenni, Roberta, Paccapelo, Alexandro, Bartolini, Stefania, Michiara, Maria, Pavesi, Giacomo, Urbini, Benedetta, Crisi, Girolamo, Cavallo, Michele A., Tosatto, Luigino, Dazzi, Claudio, Biasini, Claudia, Pasini, Giuseppe, Balestrini, Damiano, Zanelli, Francesca, Ramponi, Vania, Fioravanti, Antonio, Giombelli, Ermanno, De Biase, Dario, Baruzzi, Agostino, and Brandes, Alba A.

Published
2018
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6. Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Author

Baldin, Elisa, Testoni, Stefania, de Pasqua, Silvia, Ferro, Salvatore, Albani, Fiorenzo, Baruzzi, Agostino, D’Alessandro, Roberto, Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E., Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall’Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., Nobile, C., and On behalf of PERNO study group

Published
2017
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7. Arcipelaghi di città. Isolamento e urbanità nelle politiche culturali dell’Unione Europea

Author

Cavalleri, F, Cavalleri, F., Cavalleri, F, and Cavalleri, F.

Abstract

The article analyses the role of the European Capital of Culture scheme as a mean of Europeanization, considering the case of Pafos in the Republic of Cyprus. The study focuses on the use of the two words “island” and “city” by the technocrats of Pafos2017 in order to understand the main aspects of EU’s identity narrative. Eu- rope is indeed considered as a semiotic community, and cultural policies as dispositifs to homogenize the Europeans’ narrative’s grammar, rather than its contents. Pafians’ self–representation stresses Pafos’ distance and isolation from Europe as well as the rest of the island, placing the city at the bottom of a chain of asymmetric relation- ships, where Pafos is always at the periphery of another more central element. The only way to change this situation is the transformation of Pafos into a proper city. The idea of a proper city seems modelled out of the idea of “world–city”, a place where fluxes of globalization connect. Therefore, Pafos2017’s aim is to remove all the conditions that caused Pafos’ isolation. Even though “island” and “city” seem in opposition to each other, they resonate into the “unity in diversity” rhetoric, which turns the differences among the peoples of Europe from weaknesses to richness. The opposition between Europe and its Others is reshaped as a matter of modernity and backwardness. Europe then appears as an archipelago of modern, vivid cities, con- nected the one to the other above a sea of marginal and forgotten land, that couldn’t compete in the race for contemporaneity.

Published
2020

8. S265: RADIOMICS AND ARTIFICIAL INTELLIGENCE FOR IDENTIFICATION AND MONITORING OF SILENT CEREBRAL INFARCTS IN SICKLE CELL DISEASE: FIRST ANALYSIS FROM THE GENOMED4ALL EUROPEAN PROJECT

Author

Boaro, M. P., primary, Biondi, R., additional, Biondini, N., additional, Collado Gimbert, A., additional, JM, E. F., additional, Pinto, V., additional, Romano, N., additional, Voi, V., additional, Ferrero, G. B., additional, Casale, M., additional, Cirillo, M., additional, Palazzi, G., additional, Cavalleri, F., additional, Forni, G. L., additional, Reggiani, G., additional, Perrotta, S., additional, Manu Pereira, M., additional, Zazo, S., additional, Marias, K., additional, De Montalembert, M., additional, Bartolucci, P., additional, van Beers, E., additional, Alvarez, F., additional, Cremonesi, F., additional, Sanavia, T., additional, Fariselli, P., additional, Castellani, G., additional, Manara, R., additional, and Colombatti, R., additional

Published
2022
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10. Correction to: Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study

Author

Franceschi, Enrico, Depenni, Roberta, Paccapelo, Alexandro, Ermani, Mario, Faedi, Marina, Sturiale, Carmelo, Michiara, Maria, Servadei, Franco, Pavesi, Giacomo, Urbini, Benedetta, Pisanello, Anna, Crisi, Girolamo, Cavallo, Michele A., Dazzi, Claudio, Biasini, Claudia, Bertolini, Federica, Mucciarini, Claudia, Pasini, Giuseppe, Baruzzi, Agostino, Brandes, Alba A., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E., Tosoni, A., Cavallo, M., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., PastoreTrossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall’Agata, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Faedi, M., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Colella, M., Fallica, E., Farneti, M., Frassoldati, A., Granieri, E., Latini, F., Monetti, C., Saletti, A., Schivalocchi, R., Sarubbo, S., Seraceni, S., Tola, M. R., Urbini, B., Zini, G., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., Nobile, C., and The PERNO Study Group

Published
2017
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11. Decision-Makers’ Cultural Influence on the Implementation of the European Capital of Culture: A Longitudinal Study

Author

Konstantinos Tsagkaridis, Flora K, and Cavalleri F

Subjects
Cultural influence, Longitudinal study, European Capital of Culture, Political science, Regional science
Abstract

Motives for nomination as Cultural Capital of Europe (ECoC) vary. Desirable post-ECoC changes include economic growth, touristic increase, job creation, infrastructure updates, cultural development and city rebranding. This research assessed changes in stakeholders’ perceptions during the ECoC and their cultural context. Three members of Pafos2017 and a member of another local organization participated in semi-structured interviews at the beginning and end of 2017, which recorded perceptions of the city/citizens, the participants’ role in the implementation of the ECoC, their goals and major obstacles, the expected legacy of the ECoC and their perception of European culture. Qualitative content analyses from Psychology and Anthropology were used. Results demonstrate a drive for cultural development, personal commitment and passion as ways to overcome problems, a disbelief in the citizens justifying a top-down approach with minimal community involvement, and traces of post-colonial influences in the definition of the new Pafos and the quality assessment of cultural products. We argue that stakeholders’ philosophy and cities’ cultural particularities explain the critical decisions affecting the ECoC’s implementation, and propose the assessment of cities’ goals and philosophy to become part of the bidding process. Based on cultural particularities, EU could appropriately guide and support cities in achieving those goals.

Published
2021
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12. City/Capital of Culture schemes in European medium-sized coastal cities: the cases of Hull (UK) and Pafos (Cyprus)

Author

Tommarchi, E. and Cavalleri, F.

Abstract

Cultural events, and in particular mega events, have long been an integral part of urban agendas as tools to foster economic development and urban regeneration in the context of inter-urban competition within capitalist economies. Policy makers in European coastal or port cities of any scale appear to be particularly keen on bidding for City/Capital of Culture titles. City/Capital of Culture events, as well as other hallmark events, should be understood longitudinally within cities’ experiences of culture and regeneration. In European medium-sized coastal cities, such events may be remarkable pivotal moments and may contribute to triggering long-term physical, socio-economic, and symbolic transformations. Despite the fact that cultural events and mega events alone are by no means sufficient to tackle structural challenges in European medium-sized coastal cities, it appears possible to argue that certain large-scale events can help local policy makers cope with issues of external perceptions and geographical and symbolic isolation.

Published
2020
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13. Erratum to: Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Author

Baldin, Elisa, Testoni, Stefania, de Pasqua, Silvia, Ferro, Salvatore, Albani, Fiorenzo, Baruzzi, Agostino, D’Alessandro, Roberto, Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Cerasoli, S., Crisci, M., Dall’Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Visani, M., Dall’Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., Nobile, C., and On behalf of PERNO study group

Published
2017
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17. Pafos2017: Etnografia di una Capitale Europea della Cultura. Antropologia delle politiche urbane e culturali nella Cipro greca.

Author

Cavalleri, F, SCARDUELLI, PIETRO GIUSEPPE TOMASO, CAVALLERI, FEDERICO, Cavalleri, F, SCARDUELLI, PIETRO GIUSEPPE TOMASO, and CAVALLERI, FEDERICO

Abstract

Questa tesi analizza da un punto di vista antropologico l’istituzione della Capitale Europea della Cultura a partire del caso etnografico di Pafos2017, una piccola cittadina nella costa sud-occidentale della Repubblica di Cipro. La ricerca accoglie la proposta dell’anthropology of policy e cerca di portare alla luce il discorso autolegittimante dell’istituzione e le sue pratiche di soggettivazione. In particolare, l’analisi è interessata al punto di vista dei personaggi maggiormente coinvolti nella manifestazione (burocrati, artisti, politici, volontari etc.), intesi come punto di contatto tra la dimensione europea e quella locale della manifestazione. La parola “città” è individuata come uno degli snodi fondamentali del discorso dell’istituzione riguardo il proprio agire, nonché come la nota saliente della rappresentazione di sé da parte degli abitanti di Pafos, che si definiscono una non-città. Da questo punto di vista, quindi, Pafos2017 è uno strumento per fare di Pafos una città vera e propria, il suo progetto è così descritto come una (ri)generazione urbana. L’atto di trasformazione della città di Pafos si inserisce nel contesto post-coloniale dell’isola, con l’obiettivo di riscattare la città dagli effetti dell’egemonia europea che relega Pafos in una situazione di marginalità ed arretratezza, al termine di una catena di rapporti di subalternità. Questa posizione priva la comunità locale della possibilità di determinare la propria identità e la costringe a portare continue prove del proprio status di moderna. Diventare una città e diventare moderni sono due affermazioni che vengono a coincidere. In seguito, viene analizzato il modello che ispira l’azione della policy, riassunto nell’idea della città creativa; essa svolge sia il ruolo di categoria d’interpretazione della realtà che di modello di sviluppo per le politiche urbane di Pafos. La costruzione di una nuova città, quindi, passa attraverso un utilizzo strumentale della cultura per ag, The thesis analyses the institution of the European Capital of Culture from an anthropological perspective on the basis of the ethnographical inquiry of Pafos, a small town in the south-west coast of Cyprus, that held the title during 2017. The research embraces the suggestion of the anthropology of policy; so that It intends to discover and highlight the self-legitimation discourse of the institution and its subjectivation practices. Though, the analysis focus on the point of view of the insiders of the institutions and the people related to it (bureaucrats, artists, politicians, volunteers etc.) who act as a connection between the local and European dimension of the event. The word “city” has been pinpointed as one of the major symbolic knots in the discourse of the institution, through which it describes its action and mission; in addition, it is a critical point of the self-representation of the pafians who think about their own town as a quasi-city. Therefore, we can say Pafos2017 acts specifically to turn Pafos into a proper city, so its project is told as an urban (re)generation. The transforming of Pafos play an important role into the post-colonial situation of the island. The European hegemony that affect Cypriot society, in fact put Pafos at the very last position of a chain of hegemony and subalternity relationships. This situation prevents the Pafos community from the possession of their own identity, exposing them to ne necessity of continuous confirmation of their status of modern. So, the ECoC’s goal is to redeem the city from the marginality in which it has fallen through modernization. Therefore, the model that give shape to the policy’s action is analysed. It is the one of the creative city, that serves both as category to understand the reality and as a model for the development of the Pafso2017 urban policy. The making of a new and proper city then it requires culture as a tool for impacting the perception of places and on the identity of the pa

Published
2019

18. Correction to: Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study (Journal of Neuro-Oncology, (2016), 128, 1, (157-162), 10.1007/s11060-016-2093-1)

Author

Franceschi, Enrico, Depenni, Roberta, Paccapelo, Alexandro, Ermani, Mario, Faedi, Marina, Sturiale, Carmelo, Michiara, Maria, Servadei, Franco, Pavesi, Giacomo, Urbini, Benedetta, Pisanello, Anna, Crisi, Girolamo, Cavallo, Michele A., Dazzi, Claudio, Biasini, Claudia, Bertolini, Federica, Mucciarini, Claudia, Pasini, Giuseppe, Baruzzi, Agostino, Brandes, Alba A., Baruzzi, A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., Brandes, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E., Tosoni, A., Cavallo, Marino, Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, Enrico, Biasini, C., Cavanna, L., Guidetti, D., Marcello, Norina, Pisanello, A., Cremonini, A. M., Guiducci, G., de Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, Stefano, Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, Vincenzo, Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall’Agata, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Faedi, M., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, Giuseppe, Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, Mario, Pasquini, Elena, Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, Greta, Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, Corrado, Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Colella, Margherita, Fallica, E., Farneti, M., Frassoldati, A., Granieri, E., Latini, F., Monetti, C., Saletti, A., Schivalocchi, R., Sarubbo, S., Seraceni, S., Tola, M. R., Urbini, B., Zini, G., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., and Nobile, C.

Subjects
Cancer Research, Oncology, Neurology, Neurology (clinical)
Published
2018

19. Which elderly newly diagnosed glioblastoma patients can benefit from radiotherapy and temozolomide? A PERNO prospective study

Author

Franceschi, Enrico, Depenni, R., Paccapelo, Alexandro, Ermani, Mario, Faedi, M., Sturiale, Carmelo, Michiara, Maria, Servadei, F., Pavesi, Giacomo, Urbini, B., Pisanello, A., Crisi, G., Cavallo, Michele A., Dazzi, C., Biasini, C., Bertolini, F., Mucciarini, C., Pasini, G., Baruzzi, Agostino, Brandes, Alba A, Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., de Pasqua, S., Testoni, S., Brandes, A., Franceschi, E., Tosoni, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Fiorica, F., Sasso, E., Cavanna, L., Guidetti, D., Marcello, N., Cremonini, A. M., Guiducci, G., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall’Agata, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Guidi, A. R., Zumaglini, F., Amadori, A., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, Stefano, Nichelli, Paolo Frigio, Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Colella, M., Fallica, E., Farneti, M., Frassoldati, A., Granieri, E., Latini, F., Monetti, C., Saletti, A., Schivalocchi, R., Sarubbo, S., Seraceni, S., Tola, M. R., Zini, G., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., Nobile, C., Franceschi, E., Depenni, R., Paccapelo, Alexandro, Ermani, Mario, Faedi, M., Sturiale, Carmelo, Michiara, Maria, Servadei, F., Pavesi, Giacomo, Urbini, B., Pisanello, A., Crisi, G., Cavallo, Michele A., Dazzi, C., Biasini, C., Bertolini, F., Mucciarini, C., Pasini, G., Baruzzi, Agostino, Brandes, Alba A., Albani, F., Calbucci, F., D’Alessandro, R., Michelucci, R., de Pasqua, S., Testoni, S., Brandes, A., Tosoni, A., Eusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Fiorica, F., Sasso, E., Cavanna, L., Guidetti, D., Marcello, N., Cremonini, A.M., Guiducci, G., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Dall’Agata, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Guidi, A.R., Zumaglini, F., Amadori, A., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Colella, M., Fallica, E., Farneti, M., Frassoldati, A., Granieri, E., Latini, F., Monetti, C., Saletti, A., Schivalocchi, R., Sarubbo, S., Seraceni, S., Tola, M.R., Zini, G., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Silini, E.M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., and Nobile, C.

Subjects
Oncology, medicine.medical_specialty, Cancer Research, medicine.medical_treatment, Dacarbazine, Population, Context (language use), NO, 03 medical and health sciences, 0302 clinical medicine, Elderly, Internal medicine, medicine, Temozolomide, Humans, MGMT methylation, Prospective Studies, Prospective cohort study, education, Promoter Regions, Genetic, Antineoplastic Agents, Alkylating, DNA Modification Methylases, Survival analysis, Aged, Aged, 80 and over, education.field_of_study, Radiotherapy, business.industry, Brain Neoplasms, Tumor Suppressor Proteins, Glioblastoma, Neurology (clinical), Neurology, DNA Methylation, Survival Analysis, Surgery, Radiation therapy, DNA Repair Enzymes, 030220 oncology & carcinogenesis, Concomitant, business, 030217 neurology & neurosurgery, medicine.drug
Abstract

The role of temozolomide concurrent with and adjuvant to radiotherapy (RT/TMZ) in elderly patients with glioblastoma (GBM) remains unclear. We evaluated the outcome of patients >70 years in the context of the Project of Emilia-Romagna Region in Neuro-Oncology (PERNO), the first Italian prospective observational population-based study in neuro-oncology. For this analysis the criteria for selecting patients enrolled in the PERNO study were: age >70 years; PS 0–3; histologically confirmed GBM; postoperative radiotherapy (RT) after surgery with or without concomitant temozolomide (TMZ) or postsurgical TMZ alone. Between January 2009 and December 2010, 76 GBM elderly patients were identified in the prospective PERNO study. Twenty-three patients did not receive any treatment after surgery, and 53 patients received postsurgical treatments (25 patients received RT alone and 28 patients RT/TMZ). Median survival was 11.1 months (95 % CI 8.8–13.5), adding temozolomide concomitant and adjuvant to radiotherapy it was 11.6 months (95 % CI 8.6–14.6), and 9.3 months (95 % CI 8.1–10.6) in patients treated with RT alone (P = 0.164). However, patients with MGMT methylated treated with RT/TMZ obtained a better survival (17.2 months, 95 % CI 11.5–22.9) (P = 0.042). No difference in terms of survival were observed if patients with MGMT unmethylated tumor received RT alone, or RT/TMZ or, in MGMT methylated tumor, if patients received radiotherapy alone. In elderly patients RT/TMZ represent a widely used approach but it is effective with methylated MGMT tumors only.

Published
2016

20. Erratum to: Incidence of neuroepithelial primary brain tumors among adult population of Emilia-Romagna Region, Italy

Author

Baldin, E, Testoni, S, de Pasqua, S, Ferro, S, Albani, F, Baruzzi, A, D'Alessandro, R, PERNO study group Participants: Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Cerasoli, S., Crisci, M., Dall’Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., (Bologna), Visani M., Dall’Agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A. ., (ForlI´-Cesena), Strumia S., Casmiro, M., Gamboni, A., (Faenza, Rasi F., RA), (Lugo, Cruciani G., Cenni, P., Dazzi, C., Guidi, A. R., (Ravenna), Zumaglini F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., (Rimini), Viti B., (Cattolica, Sintini M., RN), Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., (Modena), Zunarelli E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., (Carpi, Stucchi C., MO), Iaccarino, C, Ragazzi, M., Rizzi, R., (Reggio Emilia), Zuccoli G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., (Ferrara), Urbini B., Giorgi, C., (Fidenza, Montanari E., PR), Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, Em., (Parma), Torelli P., Immovilli, P., Morelli, N., (Piacenza), Vanzo C., Nobile, C. (Padova)., Elisa Baldin, Stefania Testoni, Silvia de Pasqua, Salvatore Ferro, Fiorenzo Albani, Agostino Baruzzi, Roberto D’Alessandro, On behalf of PERNO study group, ELENA BONORA, and DARIO DE BIASE

Subjects
Psychiatry and Mental Health, Dermatology, General Medicine, Neurology (clinical)
Abstract

Unfortunately, some of the participants of the PERNO Study Group are missing in the original publication of the article. The correct details are given below: Participants: Agati R., Ambrosetto G., Bacci A., Baldin E., Baldrati A., Barbieri E., Bartolini S., Bellavista E., Bisulli F., Bonora E., Bunkheila F., Carelli V., Cerasoli S., Crisci M., Dall’Occa P., de Biase D., Ferro S., Franceschi C., Frezza G., GrassoV., Leonardi M., Marucci G., Morandi L., Mostacci B., Palandri G., Pasini E., Pastore Trossello M., Pession A., Poggi R., Riguzzi P., Rinaldi R., Rizzi S., Romeo G., Spagnolli F., Tinuper P., Trocino C., Visani M. (Bologna), Dall’Agata M., Faedi M., Frattarelli M., Gentili G., Giovannini A., Iorio P., Pasquini U., Galletti G., Guidi C., Neri W., Patuelli A.., Strumia S. (ForlÍ-Cesena), Casmiro M., Gamboni A., Rasi F. (Faenza, RA), Cruciani G. (Lugo, RA), Cenni P., Dazzi C., Guidi A.R., Zumaglini F. (Ravenna), Amadori A., Pasini G., Pasquinelli M., Pasquini E., Polselli A., Ravasio A., Viti B. (Rimini), Sintini M. (Cattolica, RN), Ariatti A., Bertolini F., Bigliardi G., Carpeggiani P., Cavalleri F., Meletti S., Nichelli P., Pettorelli E., Pinna G., Zunarelli E. (Modena), Artioli F., Bernardini I., Costa M., Greco G., Guerzoni R., Stucchi C. (Carpi, MO), Iaccarino C., Ragazzi M., Rizzi R., Zuccoli G. (Reggio Emilia), Api P., Cartei F., Fallica E., Granieri E., Latini F., Lelli G., Monetti C., Saletti A., Schivalocchi R., Seraceni S., Tola M.R., Urbini B. (Ferrara), Giorgi C., Montanari E. (Fidenza, PR), Cerasti D., Crafa P., Dascola I., Florindo I., Giombelli E., Mazza S., Ramponi V., Servadei F., Silini EM., Torelli P. (Parma), Immovilli P., Morelli N., Vanzo C. (Piacenza), Nobile C. (Padova).

Published
2017

22. Psychological care of the diabetic patient

Author

Cavalleri F, Magro G, Giordana C, Falco G, Gianotti L, De Donno, Piacenza A, and Anfossi M

Subjects
Type 1 diabetes, medicine.medical_specialty, Adrenal disorder, business.industry, Type 2 diabetes, Hypoglycemia, medicine.disease, Diabetic Eye Disease, Diabetes mellitus, medicine, Glucose homeostasis, Hormone metabolism, business, Intensive care medicine
Published
2018
Full Text
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23. Erratum to: Survival prediction in high-grade gliomas using CT perfusion imaging [J Neurooncol (2015) 123, 93-102, DOI 10.1007/s11060-015-1766-5]

Author

Yeung T. P. C., Wang Y., He W., Urbini B., Gafa R., Ulazzi L., Yartsev S., Bauman G., Lee T. -Y., Fainardi E., Baruzzi A., Albani F., Calbucci F., D'alessandro R., Michelucci R., Brandes A., Eusebi V., Ceruti S., Tamarozzi R., Emiliani E., Cavallo M., Franceschi E., Tosoni A., Fiorica F., Valentini A., Depenni R., Mucciarini C., Crisi G., Sasso E., Biasini C., Cavanna L., Guidetti D., Marcello N., Pisanello A., Cremonini A. M., Guiducci G., de Pasqua S., Testoni S., Agati R., Ambrosetto G., Bacci A., Baldin E., Baldrati A., Barbieri E., Bartolini S., Bellavista E., Bisulli F., Bonora E., Bunkheila F., Carelli V., Crisci M., Dall'occa P., de Biase D., Ferro S., Franceschi C., Frezza G., Grasso V., Leonardi M., Marucci G., Morandi L., Mostacci B., Palandri G., Pasini E., Pastore Trossello M., Pession A., Poggi R., Riguzzi P., Rinaldi R., Rizzi S., Romeo G., Spagnolli F., Tinuper P., Trocino C., Dall'agata M., Frattarelli M., Gentili G., Giovannini A., Iorio P., Pasquini U., Galletti G., Guidi C., Neri W., Patuelli A., Strumia S., Faedi M., Casmiro M., Gamboni A., Rasi F., Cruciani G., Cenni P., Dazzi C., Guidi A. R., Zumaglini F., Amadori A., Pasini G., Pasquinelli M., Pasquini E., Polselli A., Ravasio A., Viti B., Sintini M., Ariatti A., Bertolini F., Bigliardi G., Carpeggiani P., Cavalleri F., Meletti S., Nichelli P., Pettorelli E., Pinna G., Zunarelli E., Artioli F., Bernardini I., Costa M., Greco G., Guerzoni R., Stucchi C., Iaccarino C., Ragazzi M., Rizzi R., Zuccoli G., Api P., Cartei F., Colella M., Fallica E., Farneti M., Frassoldati A., Granieri E., Latini F., Monetti C., Saletti A., Schivalocchi R., Sarubbo S., Seraceni S., Tola M. R., Zini G., Giorgi C., Montanari E., Cerasti D., Crafa P., Dascola I., Florindo I., Giombelli E., Mazza S., Ramponi V., Servadei F., Silini E. M., Torelli P., Immovilli P., Morelli N., Vanzo C., Nobile C., Yeung T.P.C., Wang Y., He W., Urbini B., Gafa R., Ulazzi L., Yartsev S., Bauman G., Lee T.-Y., Fainardi E., Baruzzi A., Albani F., Calbucci F., D'alessandro R., Michelucci R., Brandes A., Eusebi V., Ceruti S., Tamarozzi R., Emiliani E., Cavallo M., Franceschi E., Tosoni A., Fiorica F., Valentini A., Depenni R., Mucciarini C., Crisi G., Sasso E., Biasini C., Cavanna L., Guidetti D., Marcello N., Pisanello A., Cremonini A.M., Guiducci G., de Pasqua S., Testoni S., Agati R., Ambrosetto G., Bacci A., Baldin E., Baldrati A., Barbieri E., Bartolini S., Bellavista E., Bisulli F., Bonora E., Bunkheila F., Carelli V., Crisci M., Dall'occa P., de Biase D., Ferro S., Franceschi C., Frezza G., Grasso V., Leonardi M., Marucci G., Morandi L., Mostacci B., Palandri G., Pasini E., Pastore Trossello M., Pession A., Poggi R., Riguzzi P., Rinaldi R., Rizzi S., Romeo G., Spagnolli F., Tinuper P., Trocino C., Dall'agata M., Frattarelli M., Gentili G., Giovannini A., Iorio P., Pasquini U., Galletti G., Guidi C., Neri W., Patuelli A., Strumia S., Faedi M., Casmiro M., Gamboni A., Rasi F., Cruciani G., Cenni P., Dazzi C., Guidi A.R., Zumaglini F., Amadori A., Pasini G., Pasquinelli M., Pasquini E., Polselli A., Ravasio A., Viti B., Sintini M., Ariatti A., Bertolini F., Bigliardi G., Carpeggiani P., Cavalleri F., Meletti S., Nichelli P., Pettorelli E., Pinna G., Zunarelli E., Artioli F., Bernardini I., Costa M., Greco G., Guerzoni R., Stucchi C., Iaccarino C., Ragazzi M., Rizzi R., Zuccoli G., Api P., Cartei F., Colella M., Fallica E., Farneti M., Frassoldati A., Granieri E., Latini F., Monetti C., Saletti A., Schivalocchi R., Sarubbo S., Seraceni S., Tola M.R., Zini G., Giorgi C., Montanari E., Cerasti D., Crafa P., Dascola I., Florindo I., Giombelli E., Mazza S., Ramponi V., Servadei F., Silini E.M., Torelli P., Immovilli P., Morelli N., Vanzo C., and Nobile C.

Subjects
PERNO, Gender, Glioblastoma, MGMT, Methylation
Abstract

Background: Clinical and molecular factors are essential to define the prognosis in patients with glioblastoma (GBM). O6-methylguanine-DNA methyltransferase (MGMT) methylation status, age, Karnofsky Performance Status (KPS), and extent of surgical resection are the most relevant prognostic factors. Our investigation of the role of gender in predicting prognosis shows a slight survival advantage for female patients. Methods: We performed a prospective evaluation of the Project of Emilia Romagna on Neuro-Oncology (PERNO) registry to identify prognostic factors in patients with GBM who received standard treatment. Results: A total of 169 patients (99 males [58.6%] and 70 females [41.4%]) were evaluated prospectively. MGMT methylation was evaluable in 140 patients. Among the male patients, 36 were MGMT methylated (25.7%) and 47 were unmethylated (33.6%); among the female patients, 32 were methylated (22.9%) and 25 were unmethylated (17.9%). Survival was longer in the methylated females compared with the methylated males (P = 0.028) but was not significantly different between the unmethylated females and the unmethylated males (P = 0.395). In multivariate analysis, gender and MGMT methylation status considered together (methylated females vs. methylated males; hazard ratio [HR], 0.459; 95% confidence interval [CI], 0.242-0.827; P = 0.017), age (HR, 1.025; 95% CI, 1.002-1.049; P = 0.032), and KPS (HR, 0.965; 95% CI, 0.948-0.982; P < 0.001) were significantly correlated with survival. Conclusions: Survival was consistently longer among MGMT methylated females compared with males. Gender can be considered as a further prognostic factor.

Published
2015

24. The Prognostic Roles of Gender and O6-Methylguanine-DNA Methyltransferase Methylation Status in Glioblastoma Patients: The Female Power

Author

Franceschi, Enrico, primary, Tosoni, Alicia, additional, Minichillo, Santino, additional, Depenni, Roberta, additional, Paccapelo, Alexandro, additional, Bartolini, Stefania, additional, Michiara, Maria, additional, Pavesi, Giacomo, additional, Urbini, Benedetta, additional, Crisi, Girolamo, additional, Cavallo, Michele A., additional, Tosatto, Luigino, additional, Dazzi, Claudio, additional, Biasini, Claudia, additional, Pasini, Giuseppe, additional, Balestrini, Damiano, additional, Zanelli, Francesca, additional, Ramponi, Vania, additional, Fioravanti, Antonio, additional, Giombelli, Ermanno, additional, De Biase, Dario, additional, Baruzzi, Agostino, additional, Brandes, Alba A., additional, Baruzzi, A., additional, Albani, F., additional, Calbucci, F., additional, D'Alessandro, R., additional, Michelucci, R., additional, Brandes, A., additional, Eusebi, V., additional, Ceruti, S., additional, Fainardi, E., additional, Tamarozzi, R., additional, Emiliani, E., additional, Cavallo, M., additional, Franceschi, E., additional, Tosoni, A., additional, Fiorica, F., additional, Valentini, A., additional, Depenni, R., additional, Mucciarini, C., additional, Crisi, G., additional, Sasso, E., additional, Biasini, C., additional, Cavanna, L., additional, Guidetti, D., additional, Marcello, N., additional, Pisanello, A., additional, Cremonini, A.M., additional, Guiducci, G., additional, de Pasqua, S., additional, Testoni, S., additional, Agati, R., additional, Ambrosetto, G., additional, Bacci, A., additional, Baldin, E., additional, Baldrati, A., additional, Barbieri, E., additional, Bartolini, S., additional, Bellavista, E., additional, Bisulli, F., additional, Bonora, E., additional, Bunkheila, F., additional, Carelli, V., additional, Crisci, M., additional, Dall'Occa, P., additional, de Biase, D., additional, Ferro, S., additional, Franceschi, C., additional, Frezza, G., additional, Grasso, V., additional, Leonardi, M., additional, Marucci, G., additional, Morandi, L., additional, Mostacci, B., additional, Palandri, G., additional, Pasini, E., additional, Pastore Trossello, M., additional, Pession, A., additional, Poggi, R., additional, Riguzzi, P., additional, Rinaldi, R., additional, Rizzi, S., additional, Romeo, G., additional, Spagnolli, F., additional, Tinuper, P., additional, Trocino, C., additional, Dall'Agata, M., additional, Frattarelli, M., additional, Gentili, G., additional, Giovannini, A., additional, Iorio, P., additional, Pasquini, U., additional, Galletti, G., additional, Guidi, C., additional, Neri, W., additional, Patuelli, A., additional, Strumia, S., additional, Faedi, M., additional, Casmiro, M., additional, Gamboni, A., additional, Rasi, F., additional, Cruciani, G., additional, Cenni, P., additional, Dazzi, C., additional, Guidi, A.R., additional, Zumaglini, F., additional, Amadori, A., additional, Pasini, G., additional, Pasquinelli, M., additional, Pasquini, E., additional, Polselli, A., additional, Ravasio, A., additional, Viti, B., additional, Sintini, M., additional, Ariatti, A., additional, Bertolini, F., additional, Bigliardi, G., additional, Carpeggiani, P., additional, Cavalleri, F., additional, Meletti, S., additional, Nichelli, P., additional, Pettorelli, E., additional, Pinna, G., additional, Zunarelli, E., additional, Artioli, F., additional, Bernardini, I., additional, Costa, M., additional, Greco, G., additional, Guerzoni, R., additional, Stucchi, C., additional, Iaccarino, C., additional, Ragazzi, M., additional, Rizzi, R., additional, Zuccoli, G., additional, Api, P., additional, Cartei, F., additional, Colella, M., additional, Fallica, E., additional, Farneti, M., additional, Frassoldati, A., additional, Granieri, E., additional, Latini, F., additional, Monetti, C., additional, Saletti, A., additional, Schivalocchi, R., additional, Sarubbo, S., additional, Seraceni, S., additional, Tola, M.R., additional, Urbini, B., additional, Zini, G., additional, Giorgi, C., additional, Montanari, E., additional, Cerasti, D., additional, Crafa, P., additional, Dascola, I., additional, Florindo, I., additional, Giombelli, E., additional, Mazza, S., additional, Ramponi, V., additional, Servadei, F., additional, Silini, E.M., additional, Torelli, P., additional, Immovilli, P., additional, Morelli, N., additional, Vanzo, C., additional, and Nobile, C., additional

Published
2018
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25. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: A systematic analysis from the global burden of disease study 2015

Author

Reitsma, MB, Fullman, N, Ng, M, Salama, JS, Abajobir, A, Abate, KH, Abbafati, C, Abera, SF, Abraham, B, Abyu, GY, Adebiyi, AO, Al-Aly, Z, Aleman, AV, Ali, R, Alkerwi, AA, Allebeck, P, Al-Raddadi, RM, Amare, AT, Amberbir, A, Ammar, W, Amrock, SM, Antonio, CAT, Asayesh, H, Atnafu, NT, Azzopardi, P, Banerjee, A, Barac, A, Barrientos-Gutierrez, T, Basto-Abreu, AC, Bazargan-Hejazi, S, Bedi, N, Bell, B, Bello, AK, Bensenor, IM, Beyene, AS, Bhala, N, Biryukov, S, Bolt, K, Brenner, H, Butt, Z, Cavalleri, F, Cercy, K, Chen, H, Christopher, DJ, Ciobanu, LG, Colistro, V, Colomar, M, Cornaby, L, Dai, X, Damtew, SA, Dandona, L, Dandona, R, Dansereau, E, Davletov, K, Dayama, A, Degfie, TT, Deribew, A, Dharmaratne, SD, DImtsu, BD, Doyle, KE, Endries, AY, Ermakov, SP, Estep, K, Faraon, EJA, Farzadfar, F, Feigin, VL, Feigl, AB, Fischer, F, Friedman, J, Ghiwot, TT, Gall, SL, Gao, W, Gillum, RF, Gold, AL, Gopalani, SV, Gotay, CC, Gupta, R, Gupta, V, Hamadeh, RR, Hankey, G, Harb, HL, Hay, SI, Horino, M, Horita, N, Hosgood, HD, Husseini, A, Ileanu, BV, Islami, F, Jiang, G, Jiang, Y, Jonas, JB, Kabir, Z, Kamal, R, Kasaeian, A, Kesavachandran, CN, Khader, YS, Khalil, I, Khang, YH, Khera, S, Mekonnen, A, Reitsma, MB, Fullman, N, Ng, M, Salama, JS, Abajobir, A, Abate, KH, Abbafati, C, Abera, SF, Abraham, B, Abyu, GY, Adebiyi, AO, Al-Aly, Z, Aleman, AV, Ali, R, Alkerwi, AA, Allebeck, P, Al-Raddadi, RM, Amare, AT, Amberbir, A, Ammar, W, Amrock, SM, Antonio, CAT, Asayesh, H, Atnafu, NT, Azzopardi, P, Banerjee, A, Barac, A, Barrientos-Gutierrez, T, Basto-Abreu, AC, Bazargan-Hejazi, S, Bedi, N, Bell, B, Bello, AK, Bensenor, IM, Beyene, AS, Bhala, N, Biryukov, S, Bolt, K, Brenner, H, Butt, Z, Cavalleri, F, Cercy, K, Chen, H, Christopher, DJ, Ciobanu, LG, Colistro, V, Colomar, M, Cornaby, L, Dai, X, Damtew, SA, Dandona, L, Dandona, R, Dansereau, E, Davletov, K, Dayama, A, Degfie, TT, Deribew, A, Dharmaratne, SD, DImtsu, BD, Doyle, KE, Endries, AY, Ermakov, SP, Estep, K, Faraon, EJA, Farzadfar, F, Feigin, VL, Feigl, AB, Fischer, F, Friedman, J, Ghiwot, TT, Gall, SL, Gao, W, Gillum, RF, Gold, AL, Gopalani, SV, Gotay, CC, Gupta, R, Gupta, V, Hamadeh, RR, Hankey, G, Harb, HL, Hay, SI, Horino, M, Horita, N, Hosgood, HD, Husseini, A, Ileanu, BV, Islami, F, Jiang, G, Jiang, Y, Jonas, JB, Kabir, Z, Kamal, R, Kasaeian, A, Kesavachandran, CN, Khader, YS, Khalil, I, Khang, YH, Khera, S, and Mekonnen, A

Abstract

Background The scale-up of tobacco control, especially after the adoption of the Framework Convention for Tobacco Control, is a major public health success story. Nonetheless, smoking remains a leading risk for early death and disability worldwide, and therefore continues to require sustained political commitment. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) offers a robust platform through which global, regional, and national progress toward achieving smoking-related targets can be assessed. Methods We synthesised 2818 data sources with spatiotemporal Gaussian process regression and produced estimates of daily smoking prevalence by sex, age group, and year for 195 countries and territories from 1990 to 2015. We analysed 38 risk-outcome pairs to generate estimates of smoking-attributable mortality and disease burden, as measured by disability-adjusted life-years (DALYs). We then performed a cohort analysis of smoking prevalence by birth-year cohort to better understand temporal age patterns in smoking. We also did a decomposition analysis, in which we parsed out changes in all-cause smoking-attributable DALYs due to changes in population growth, population ageing, smoking prevalence, and risk-deleted DALY rates. Finally, we explored results by level of development using the Socio-demographic Index (SDI). Findings Worldwide, the age-standardised prevalence of daily smoking was 25·0% (95% uncertainty interval [UI] 24·2-25·7) for men and 5·4% (5·1-5·7) for women, representing 28·4% (25·8-31·1) and 34·4% (29·4-38·6) reductions, respectively, since 1990. A greater percentage of countries and territories achieved significant annualised rates of decline in smoking prevalence from 1990 to 2005 than in between 2005 and 2015; however, only four countries had significant annualised increases in smoking prevalence between 2005 and 2015 (Congo [Brazzaville] and Azerbaijan

Published
2017

26. Smoking prevalence and attributable disease burden in 195 countries and territories, 1990-2015: a systematic analysis from the Global Burden of Disease Study 2015

Author

Reitsma, M., Fullman, N., Ng, M., Salama, J., Abajobir, A., Abate, K., Abbafati, C., Abera, S., Abraham, B., Abyu, G., Adebiyi, A., Al-Aly, Z., Aleman, A., Ali, R., Al Alkerwi, A., Allebeck, P., Al-Raddadi, R., Amare, A., Amberbir, A., Ammar, W., Amrock, S., Antonio, C., Asayesh, H., Atnafu, N., Azzopardi, P., Banerjee, A., Barac, A., Barrientos-Gutierrez, T., Basto-Abreu, A., Bazargan-Hejazi, S., Bedi, N., Bell, B., Bello, A., Bensenor, I., Beyene, A., Bhala, N., Biryukov, S., Bolt, K., Brenner, H., Butt, Z., Cavalleri, F., Cercy, K., Chen, H., Christopher, D., Ciobanu, L., Colistro, V., Colomar, M., Cornaby, L., Dai, X., Damtew, S., Dandona, L., Dandona, R., Dansereau, E., Davletov, K., Dayama, A., Degfie, T., Deribew, A., Dharmaratne, S., Dimtsu, B., Doyle, K., Endries, A., Ermakov, S., Estep, K., Faraon, E., Farzadfar, F., Feigin, V., Feigl, A., Fischer, F., Friedman, J., Ghiwot, T., Gall, S., Gao, W., Gillum, R., Gold, A., Gopalani, S., Gotay, C., Gupta, R., Gupta, V., Hamadeh, R., Hankey, G., Harb, H., Hay, S., Horino, M., Horita, N., Hosgood, H., Husseini, A., Ileanu, B., Islami, F., Jiang, G., Jiang, Y., Jonas, J., Kabir, Z., Kamal, R., Kasaeian, A., Kesavachandran, C., Khader, Y., Khalil, I., Khang, Y., Khera, S., Khubchandani, J., Kim, D., Kim, Y., Kimokoti, R., Kinfu, Y., Knibbs, L., Kokubo, Y., Kolte, D., Kopec, J., Kosen, S., Kotsakis, G., Koul, P., Koyanagi, A., Krohn, K., Krueger, H., Defo, B., Bicer, B., Kulkarni, C., Kumar, G., Leasher, J., Lee, A., Leinsalu, M., Li, T., Linn, S., Liu, P., Liu, S., Lo, L., Lopez, A., Ma, S., Abd El Razek, H., Majeed, A., Malekzadeh, R., Malta, D., Manamo, W., Martinez-Raga, J., Mekonnen, A., Mendoza, W., Miller, Ted, Mohammad, K., Morawska, L., Musa, K., Nagel, G., Neupane, S., Quyen, N., Nguyen, G., Oh, I., Oyekale, A., Mahesh, P., Pana, A., Park, E., Patil, S., Patton, G., Pedro, J., Qorbani, M., Rafay, A., Rahman, M., Rai, R., Ram, U., Ranabhat, C., Refaat, A., Reinig, N., Roba, H., Rodriguez, A., Roman, Y., Roth, G., Roy, A., Sagar, R., Salomon, J., Sanabria, J., Santos, I., Sartorius, B., Satpathy, M., Sawhney, M., Sawyer, S., Saylan, M., Schaub, M., Schluger, N., Schutte, A., Sepanlou, S., Serdar, B., Shaikh, M., She, J., Shin, M., Shiri, R., Shishani, K., Shiue, I., Sigfusdottir, I., Silverberg, J., Singh, J., Singh, V., Slepak, E., Soneji, S., Soriano, J., Soshnikov, S., Sreeramareddy, C., Stein, D., Stranges, S., Subart, M., Swaminathan, S., Szoeke, C., Tefera, W., Topor-Madry, R., Tran, B., Tsilimparis, N., Tymeson, H., Ukwaja, K., Updike, R., Uthman, O., Violante, F., Vladimirov, S., Vlassov, V., Vollset, S., Vos, T., Weiderpass, E., Wen, C., Werdecker, A., Wilson, S., Wubshet, M., Xiao, L., Yakob, B., Yano, Y., Ye, P., Yonemoto, N., Yoon, S., Younis, M., Yu, C., Zaidi, Z., Zaki, M., Zhang, A., Zipkin, B., Murray, C., Forouzanfar, M., Gakidou, E., Reitsma, M., Fullman, N., Ng, M., Salama, J., Abajobir, A., Abate, K., Abbafati, C., Abera, S., Abraham, B., Abyu, G., Adebiyi, A., Al-Aly, Z., Aleman, A., Ali, R., Al Alkerwi, A., Allebeck, P., Al-Raddadi, R., Amare, A., Amberbir, A., Ammar, W., Amrock, S., Antonio, C., Asayesh, H., Atnafu, N., Azzopardi, P., Banerjee, A., Barac, A., Barrientos-Gutierrez, T., Basto-Abreu, A., Bazargan-Hejazi, S., Bedi, N., Bell, B., Bello, A., Bensenor, I., Beyene, A., Bhala, N., Biryukov, S., Bolt, K., Brenner, H., Butt, Z., Cavalleri, F., Cercy, K., Chen, H., Christopher, D., Ciobanu, L., Colistro, V., Colomar, M., Cornaby, L., Dai, X., Damtew, S., Dandona, L., Dandona, R., Dansereau, E., Davletov, K., Dayama, A., Degfie, T., Deribew, A., Dharmaratne, S., Dimtsu, B., Doyle, K., Endries, A., Ermakov, S., Estep, K., Faraon, E., Farzadfar, F., Feigin, V., Feigl, A., Fischer, F., Friedman, J., Ghiwot, T., Gall, S., Gao, W., Gillum, R., Gold, A., Gopalani, S., Gotay, C., Gupta, R., Gupta, V., Hamadeh, R., Hankey, G., Harb, H., Hay, S., Horino, M., Horita, N., Hosgood, H., Husseini, A., Ileanu, B., Islami, F., Jiang, G., Jiang, Y., Jonas, J., Kabir, Z., Kamal, R., Kasaeian, A., Kesavachandran, C., Khader, Y., Khalil, I., Khang, Y., Khera, S., Khubchandani, J., Kim, D., Kim, Y., Kimokoti, R., Kinfu, Y., Knibbs, L., Kokubo, Y., Kolte, D., Kopec, J., Kosen, S., Kotsakis, G., Koul, P., Koyanagi, A., Krohn, K., Krueger, H., Defo, B., Bicer, B., Kulkarni, C., Kumar, G., Leasher, J., Lee, A., Leinsalu, M., Li, T., Linn, S., Liu, P., Liu, S., Lo, L., Lopez, A., Ma, S., Abd El Razek, H., Majeed, A., Malekzadeh, R., Malta, D., Manamo, W., Martinez-Raga, J., Mekonnen, A., Mendoza, W., Miller, Ted, Mohammad, K., Morawska, L., Musa, K., Nagel, G., Neupane, S., Quyen, N., Nguyen, G., Oh, I., Oyekale, A., Mahesh, P., Pana, A., Park, E., Patil, S., Patton, G., Pedro, J., Qorbani, M., Rafay, A., Rahman, M., Rai, R., Ram, U., Ranabhat, C., Refaat, A., Reinig, N., Roba, H., Rodriguez, A., Roman, Y., Roth, G., Roy, A., Sagar, R., Salomon, J., Sanabria, J., Santos, I., Sartorius, B., Satpathy, M., Sawhney, M., Sawyer, S., Saylan, M., Schaub, M., Schluger, N., Schutte, A., Sepanlou, S., Serdar, B., Shaikh, M., She, J., Shin, M., Shiri, R., Shishani, K., Shiue, I., Sigfusdottir, I., Silverberg, J., Singh, J., Singh, V., Slepak, E., Soneji, S., Soriano, J., Soshnikov, S., Sreeramareddy, C., Stein, D., Stranges, S., Subart, M., Swaminathan, S., Szoeke, C., Tefera, W., Topor-Madry, R., Tran, B., Tsilimparis, N., Tymeson, H., Ukwaja, K., Updike, R., Uthman, O., Violante, F., Vladimirov, S., Vlassov, V., Vollset, S., Vos, T., Weiderpass, E., Wen, C., Werdecker, A., Wilson, S., Wubshet, M., Xiao, L., Yakob, B., Yano, Y., Ye, P., Yonemoto, N., Yoon, S., Younis, M., Yu, C., Zaidi, Z., Zaki, M., Zhang, A., Zipkin, B., Murray, C., Forouzanfar, M., and Gakidou, E.

Abstract

Background: The scale-up of tobacco control, especially after the adoption of the Framework Convention for Tobacco Control, is a major public health success story. Nonetheless, smoking remains a leading risk for early death and disability worldwide, and therefore continues to require sustained political commitment. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) offers a robust platform through which global, regional, and national progress toward achieving smoking-related targets can be assessed. Methods: We synthesised 2818 data sources with spatiotemporal Gaussian process regression and produced estimates of daily smoking prevalence by sex, age group, and year for 195 countries and territories from 1990 to 2015. We analysed 38 risk-outcome pairs to generate estimates of smoking-attributable mortality and disease burden, as measured by disability-adjusted life-years (DALYs). We then performed a cohort analysis of smoking prevalence by birth-year cohort to better understand temporal age patterns in smoking. We also did a decomposition analysis, in which we parsed out changes in all-cause smoking-attributable DALYs due to changes in population growth, population ageing, smoking prevalence, and risk-deleted DALY rates. Finally, we explored results by level of development using the Socio-demographic Index (SDI). Findings: Worldwide, the age-standardised prevalence of daily smoking was 25·0% (95% uncertainty interval [UI] 24·2–25·7) for men and 5·4% (5·1–5·7) for women, representing 28·4% (25·8–31·1) and 34·4% (29·4–38·6) reductions, respectively, since 1990. A greater percentage of countries and territories achieved significant annualised rates of decline in smoking prevalence from 1990 to 2005 than in between 2005 and 2015; however, only four countries had significant annualised increases in smoking prevalence between 2005 and 2015 (Congo [Brazzaville] and Azerbaijan for men and Kuwait and Timor-Leste for women). In 2015, 11·5% of global deaths (

Published
2017

27. Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Author

Karema C.K., Kajungu D.K., Kalkonde Y., Kamal R., Kesavachandran C.N., She J., Kan H., Kandel A., Karch A., Karimkhani C., Kaul A., Kazi D.S., Keiyoro P.N., Lyons R.A., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khang Y.H., Won S., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kim Y.J., Skogen J.C., Savic M., Kokubo Y., Kolte D., Koul P.A., Koyanagi A., Kuate B., Kuchenbecker R.S., Kucuk B., Kuipers E.J., Lallukka T., Shiri R., Meretoja T.J., Latif A.A., Lavados P.M., Lawrynowicz A.E.B., Leasher J.L., Leung R., Li Y., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Logroscino G., Looker K.J., Rai D., Lunevicius R., Magdy H., Mahdavi M., Malta D.C., Marcenes W., Martinez-Raga J., Mason-Jones A.J., McKee M., Murthy G.V.S., Meaney P.A., Memiah P., Memish Z.A., Mendoza W., Mhimbira F.A., Miller T.R., Mills E.J., Mirrakhimov E.M., Mohammad K.A., Mohammadi A., Monasta L., Montico M., Ronfani L., Werdecker A., Mueller U.O., Westerman R., Murdoch M.E., Nachega J.B., Tran B.X., Naheed A., Naldi L., Nangia V., Ngalesoni F.N., Nguyen Q.L., Nkamedjie P.M., Nolla J.M., Norman R.E., Obermeyer C.M., Ogbo F.A., Oh I., Oladimeji O., Sartorius B., Olivares P.R., Olusanya B.O., Olusanya J.O., Oren E., Ortiz A., Ota E., Schutte A.E., Oyekale A.S., Pa M., Park E., Patten S.B., Tonelli M., Pereira D.M., Pesudovs K., Pillay J.D., Plass D., Polinder S., Prasad N.M., Qorbani M., Radfar A., Rafay A., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Ranganathan K., Refaat A.H., Ribeiro A.L., Ricci S., Rojas-Rueda D., Sackey B.B., Sanabria J.R., Sanchez-Nino M.D., Sarmiento-Suarez R., Sawhney M., Schneider I.J.C., Silva D.A.S., Schwebel D.C., Singh J.A., Shahraz S., Shaikh M.A., Sharma R., Shigematsu M., Shin M., Yoon S., Sigfusdottir I.D., Silverberg J.I., Yano Y., Singh P.K., Soreide K., Sreeramareddy C.T., Stathopoulou V., Stein M.B., Stovner L.J., Stranges S., Stroumpoulis K., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tanne D., Tavakkoli M., Taye B., Tuzcu E.M., Thakur J., Thomson A.J., Thurston G.D., Tobe-Gai R., Topor-Madry R., Topouzis F., Truelsen T., Tsala Z., Tsilimbaris M., Tyrovolas S., Ukwaja K.N., Uneke C.J., Uthman O.A., van Gool C.H., van Os J., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Violante F.S., Vlassov V.V., Wallin M.T., Weichenthal S., Williams H.C., Woldeyohannes S.M., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Younis M.Z., Yu C., Zaidi Z., Zaki M.E., Zeeb H., Zuhlke L.J., Brown J., Singh A., Thrift A.G., Wang L., Kassebaum N.J., Arora M., Barber R.M., Carter A., Casey D.C., Charlson F.J., Coates M.M., Coggeshall M., Cornaby L., Dandona L., Dicker D.J., Erskine H.E., Ferrari A.J., Fitzmaurice C., Foreman K., Forouzanfar M.H., Fullman N., Goldberg E.M., Graetz N., Haagsma J.A., Hay S.I., Johnson C.O., Kemmer L., Khalil I.A., Kinfu Y., Kutz M.J., Kyu H.H., Leung J., Lim S.S., Lozano R., Mikesell J., Mokdad A.H., Mooney M.D., Naghavi M., Nguyen G., Nsoesie E., Pigott D.M., Pinho C., Rankin Z., Reinig N., Sandar L., Smith A., Sorensen R.J.D., Stanaway J., Steiner C., Teeple S., Thomas B.A., Troeger C., VanderZanden A., Wagner J.A., Wanga V., Whiteford H.A., Zhou M., Zoeckler L., Achoki T., Afshin A., Alexander L.T., Allen C., Anderson G.M., Bell B., Bienhoff K., Biryukov S., Blore J.D., Estep K., Friedman J., Frostad J., Godwin W.W., Liu P.Y., Masiye F., Millear A., Mirarefin M., Moradi-Lakeh M., Mumford J.E., Ng M., Reitsma M.B., Reynolds A., Roth G.A., Sur P.J., Vollset S.E., Vos T., Lopez A.D., Murray C.J.L., Ellenbogen R.G., Mock C.N., Anderson B.O., Futran N.D., Bhutta Z.A., Nisar M.I., Akseer N., deVeber G.A., Abajobir A.A., Knibbs L.D., Lalloo R., Alam N.K.M., Gouda H.N., Guo Y., McGrath J.J., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Bisanzio D., Ali R., Bennett D.A., Jha V., Rahimi K., Duan L., Jin Y., Ye P., Liang X., Mensah G.A., Salomon J.A., Thorne-Lyman A.L., Barnighausen T., Campos-Nonato I.R., Ding E.L., Farvid M.S., Wagner G.R., Fitchett J.R.A., Abate K.H., Ahmed M.B., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abraham B., Abubakar I., Banerjee A., Abu-Raddad L.J., Abu-Rmeileh N.M., Ackerman I.N., Buchbinder R., Gabbe B., Lloyd B.K., Adebiyi A.O., Adedeji I.A., Adsuar J.C., Afanvi K.A., Agardh E.E., Badawi A., Popova S., Agarwal A., Agarwal S.K., Roy A., Sagar R., Satpathy M., Tandon N., Ahmad Kiadaliri A., Norrving B., Ahmadieh H., Yaseri M., Katibeh M., Al-Aly Z., Alam K., Azzopardi P., Borschmann R., Colquhoun S.M., Patton G.C., Weintraub R.G., Meretoja A., Szoeke C.E.I., Taylor H.R., Wijeratne T., Driscoll T.R., Leigh J., Kemp A.H., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Alegretti M.A., Aleman A.V., Cavalleri F., Colistro V., Alemu Z.A., Tegegne T.K., Alkerwi A., Alla F., Allebeck P., Rabiee R.H.S., Carrero J.J., Fereshtehnejad S.M., Kivipelto M., Weiderpass E., Havmoeller R., Sindi S., Alsharif U., Alvarez E., Alvis-Guzman N., Amare A.T., Melaku Y.A., Ciobanu L.G., Tessema G.A., Amberbir A., Amegah A.K., Ameh E.A., Amini H., Furst T., Ammar W., Harb H.L., Amrock S.M., Zonies D., Antonio C.A.T., Anwari P., Arnlov J., Larsson A., Arsic V.S., Barac A., Artaman A., Asayesh H., Asghar R.J., Avokpaho E.F.G.A., Gankpe F.G., Awasthi A., Ayala B.P., Bacha U., Balakrishnan K., Barker-Collo S.L., Mohammed S., Barregard L., Petzold M., Barrero L.H., Basu S., Del L.C., Bayou T.A., Betsu B.D., Hailu G.B., Tekle D.Y., Beardsley J., Bedi N., Beghi E., Sheth K.N., Bell M.L., Huang J.J., Benjet C., Gutierrez R.A., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D., Bernabe E., Hay R.J., Roba H.S., Beyene A.S., Hassen T.A., Mesfi Y.M., Bhala N., Bhansali A., Piel F.B., Steiner T.J., Bhatt S., Majeed A., Soljak M., Biadgilign S., Bikbov B., Bin A.A., Bjertness E., Bourne R.R.A., Brainin M., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Brenner H., Brugha T.S., Buckle G.C., Butt Z.A., Calabria B., Lucas R.M., Boufous S., Degenhardt L., Resnikoff S., Mitchell P.B., Campuzano J.C., Gomez-Dantes H., Heredia-Pi I.B., Jauregui A., Montanez Hernandez J.C., Servan-Mori E.E., Carabin H., Carapetis J.R., Cardenas R., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Chang J., Chiang P.P., Chibalabala M., Chibueze C.E., Mori R., Chisumpa V.H., Choi J.J., Choudhury L., Christensen H., Colomar M., Crump J.A., Derrett S., Poulton R.G., Giussani G., Cortinovis M., Perico N., Remuzzi G., Dargan P.I., das Neves J., Pedro J.M., Santos J.V., Davey G., Davis A.C., Newton J.N., Steel N., De Leo D., Des Jarlais D.C., Dharmaratne S.D., Dhillon P.K., Zodpey S., Doyle K.E., Dubey M., Rahman M.H.U., Ram U., Yadav A.K., Duncan B.B., Kieling C., Schmidt M.I., Ebrahimi H., Esteghamati A., Farzadfar F., Hafezi-Nejad N., Kasaeian A., Parsaeian M., Pishgar F., Sheikhbahaei S., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Hassanvand M.S., Heydarpour P., Rahimi-Movaghar V., Elyazar I., Endries A.Y., Ermakov S.P., Eshrati B., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Te B.J., Fernandes J.G., Fernandes J.C., Fischer F., Foigt N., Fowkes F.G.R., Franklin R.C., Garcia-Basteiro A.L., Geleijnse J.M., Jibat T., Gibney K.B., Gillum R.F., Mehari A., Ginawi I.A., Hailu A.D., Giref A.Z., Haile D., Giroud M., Gishu M.D., Tura A.K., Gona P., Goodridge A., Gopalani S.V., Gotay C.C., Kissoon N., Kopec J.A., Pourmalek F., Goto A., Inoue M., Gugnani H., Gupta R., Gupta V., Knudsen A.K., Norheim O.F., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Hammami M., Handal A.J., Hankey G.J., Harikrishnan S., Haro J.M., Hedayati M.T., Hoek H.W., Skirbekk V., Hoff D.J., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Huang H., Iburg K.M., Idrisov B.T., Kwan G.F., Innos K., Kawakami N., Shibuya K., Jacobsen K.H., Jayatilleke A.U., Jiang G., Jiang Y., Jimenez-Corona A., Jonas J.B., Kabir Z., Karema C.K., Kajungu D.K., Kalkonde Y., Kamal R., Kesavachandran C.N., She J., Kan H., Kandel A., Karch A., Karimkhani C., Kaul A., Kazi D.S., Keiyoro P.N., Lyons R.A., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khang Y.H., Won S., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kim Y.J., Skogen J.C., Savic M., Kokubo Y., Kolte D., Koul P.A., Koyanagi A., Kuate B., Kuchenbecker R.S., Kucuk B., Kuipers E.J., Lallukka T., Shiri R., Meretoja T.J., Latif A.A., Lavados P.M., Lawrynowicz A.E.B., Leasher J.L., Leung R., Li Y., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Logroscino G., Looker K.J., Rai D., Lunevicius R., Magdy H., Mahdavi M., Malta D.C., Marcenes W., Martinez-Raga J., Mason-Jones A.J., McKee M., Murthy G.V.S., Meaney P.A., Memiah P., Memish Z.A., Mendoza W., Mhimbira F.A., Miller T.R., Mills E.J., Mirrakhimov E.M., Mohammad K.A., Mohammadi A., Monasta L., Montico M., Ronfani L., Werdecker A., Mueller U.O., Westerman R., Murdoch M.E., Nachega J.B., Tran B.X., Naheed A., Naldi L., Nangia V., Ngalesoni F.N., Nguyen Q.L., Nkamedjie P.M., Nolla J.M., Norman R.E., Obermeyer C.M., Ogbo F.A., Oh I., Oladimeji O., Sartorius B., Olivares P.R., Olusanya B.O., Olusanya J.O., Oren E., Ortiz A., Ota E., Schutte A.E., Oyekale A.S., Pa M., Park E., Patten S.B., Tonelli M., Pereira D.M., Pesudovs K., Pillay J.D., Plass D., Polinder S., Prasad N.M., Qorbani M., Radfar A., Rafay A., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Ranganathan K., Refaat A.H., Ribeiro A.L., Ricci S., Rojas-Rueda D., Sackey B.B., Sanabria J.R., Sanchez-Nino M.D., Sarmiento-Suarez R., Sawhney M., Schneider I.J.C., Silva D.A.S., Schwebel D.C., Singh J.A., Shahraz S., Shaikh M.A., Sharma R., Shigematsu M., Shin M., Yoon S., Sigfusdottir I.D., Silverberg J.I., Yano Y., Singh P.K., Soreide K., Sreeramareddy C.T., Stathopoulou V., Stein M.B., Stovner L.J., Stranges S., Stroumpoulis K., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tanne D., Tavakkoli M., Taye B., Tuzcu E.M., Thakur J., Thomson A.J., Thurston G.D., Tobe-Gai R., Topor-Madry R., Topouzis F., Truelsen T., Tsala Z., Tsilimbaris M., Tyrovolas S., Ukwaja K.N., Uneke C.J., Uthman O.A., van Gool C.H., van Os J., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Violante F.S., Vlassov V.V., Wallin M.T., Weichenthal S., Williams H.C., Woldeyohannes S.M., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Younis M.Z., Yu C., Zaidi Z., Zaki M.E., Zeeb H., Zuhlke L.J., Brown J., Singh A., Thrift A.G., Wang L., Kassebaum N.J., Arora M., Barber R.M., Carter A., Casey D.C., Charlson F.J., Coates M.M., Coggeshall M., Cornaby L., Dandona L., Dicker D.J., Erskine H.E., Ferrari A.J., Fitzmaurice C., Foreman K., Forouzanfar M.H., Fullman N., Goldberg E.M., Graetz N., Haagsma J.A., Hay S.I., Johnson C.O., Kemmer L., Khalil I.A., Kinfu Y., Kutz M.J., Kyu H.H., Leung J., Lim S.S., Lozano R., Mikesell J., Mokdad A.H., Mooney M.D., Naghavi M., Nguyen G., Nsoesie E., Pigott 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G.R., Fitchett J.R.A., Abate K.H., Ahmed M.B., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abraham B., Abubakar I., Banerjee A., Abu-Raddad L.J., Abu-Rmeileh N.M., Ackerman I.N., Buchbinder R., Gabbe B., Lloyd B.K., Adebiyi A.O., Adedeji I.A., Adsuar J.C., Afanvi K.A., Agardh E.E., Badawi A., Popova S., Agarwal A., Agarwal S.K., Roy A., Sagar R., Satpathy M., Tandon N., Ahmad Kiadaliri A., Norrving B., Ahmadieh H., Yaseri M., Katibeh M., Al-Aly Z., Alam K., Azzopardi P., Borschmann R., Colquhoun S.M., Patton G.C., Weintraub R.G., Meretoja A., Szoeke C.E.I., Taylor H.R., Wijeratne T., Driscoll T.R., Leigh J., Kemp A.H., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Alegretti M.A., Aleman A.V., Cavalleri F., Colistro V., Alemu Z.A., Tegegne T.K., Alkerwi A., Alla F., Allebeck P., Rabiee R.H.S., Carrero J.J., Fereshtehnejad S.M., Kivipelto M., Weiderpass E., Havmoeller R., Sindi S., Alsharif U., Alvarez E., Alvis-Guzman N., Amare A.T., Melaku Y.A., Ciobanu 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Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Te B.J., Fernandes J.G., Fernandes J.C., Fischer F., Foigt N., Fowkes F.G.R., Franklin R.C., Garcia-Basteiro A.L., Geleijnse J.M., Jibat T., Gibney K.B., Gillum R.F., Mehari A., Ginawi I.A., Hailu A.D., Giref A.Z., Haile D., Giroud M., Gishu M.D., Tura A.K., Gona P., Goodridge A., Gopalani S.V., Gotay C.C., Kissoon N., Kopec J.A., Pourmalek F., Goto A., Inoue M., Gugnani H., Gupta R., Gupta V., Knudsen A.K., Norheim O.F., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Hammami M., Handal A.J., Hankey G.J., Harikrishnan S., Haro J.M., Hedayati M.T., Hoek H.W., Skirbekk V., Hoff D.J., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Huang H., Iburg K.M., Idrisov B.T., Kwan G.F., Innos K., Kawakami N., Shibuya K., Jacobsen K.H., Jayatilleke A.U., Jiang G., Jiang Y., Jimenez-Corona A., Jonas J.B., and Kabir Z.

Abstract

Background Healthy life expectancy (HALE) and disability-adjusted life-years (DALYs) provide summary measures of health across geographies and time that can inform assessments of epidemiological patterns and health system performance, help to prioritise investments in research and development, and monitor progress toward the Sustainable Development Goals (SDGs). We aimed to provide updated HALE and DALYs for geographies worldwide and evaluate how disease burden changes with development. Methods We used results from the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015) for all-cause mortality, cause-specific mortality, and non-fatal disease burden to derive HALE and DALYs by sex for 195 countries and territories from 1990 to 2015. We calculated DALYs by summing years of life lost (YLLs) and years of life lived with disability (YLDs) for each geography, age group, sex, and year. We estimated HALE using the Sullivan method, which draws from age-specific death rates and YLDs per capita. We then assessed how observed levels of DALYs and HALE differed from expected trends calculated with the Socio-demographic Index (SDI), a composite indicator constructed from measures of income per capita, average years of schooling, and total fertility rate. Findings Total global DALYs remained largely unchanged from 1990 to 2015, with decreases in communicable, neonatal, maternal, and nutritional (Group 1) disease DALYs offset by increased DALYs due to non-communicable diseases (NCDs). Much of this epidemiological transition was caused by changes in population growth and ageing, but it was accelerated by widespread improvements in SDI that also correlated strongly with the increasing importance of NCDs. Both total DALYs and age-standardised DALY rates due to most Group 1 causes significantly decreased by 2015, and although total burden climbed for the majority of NCDs, age-standardised DALY rates due to NCDs declined. Nonetheless, age-standardised DALY rates d

Published
2016

28. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015.

Author

Alhabib S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Xiao Q., Lo L., Logroscino G., Lunevicius R., Ma S., Machado V.M., Mackay M.T., Magdy Abd El Razek H., Magdy Abd El Razek M., Mandisarisa J., Mangalam S., Marcenes W., Meaney P.A., Margolis D.J., Silberberg D.H., Martin G.R., Martinez-Raga J., Marzan M.B., Mason-Jones A.J., McMahon B.J., Mehndiratta M.M., Woldeyohannes S.M., Tedla B.A., Zeleke B.M., Memiah P., Memish Z.A., Mendoza W., Meretoja T.J., Lallukka T., Mhimbira F.A., Micha R., Mozaff D., Shi P., Singh G.M., Miller T.R., Mohammad K.A., Mohammadi A., Mohan V., Mola G.L.D., Monasta L., Montico M., Ronfani L., Morawska L., Werdecker A., Mueller U.O., Westerman R., Musa K.I., Paternina Caicedo A.J., Seedat S., Nagel G., Rothenbacher D., Naidoo K.S., Sartorius B., Naldi L., Remuzzi G., Nangia V., Nash D., Nejjari C., Neupane S., Newton C.R., Ngalesoni F.N., Ngirabega J.D., Nguyen Q.L., Nkamedjie Pete P.M., Nomura M., Nyakarahuka L., Ogbo F.A., Ohkubo T., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Ozdemir R., Mahesh P.A., Pandian J.D., Pant P.R., Papachristou C., Park E., Park J., Patten S.B., Tonelli M., Stokic Pejin L., Pereira D.M., Cortinovis M., Giussani G., Perico N., Pesudovs K., Pillay J.D., Plass D., Platts-Mills J.A., Polinder S., Pope C.A., Qorbani M., Rafay A., Rana S.M., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rakovac I., Ranabhat C.L., Rangaswamy T., Ribeiro A.L., Ricci S., Roca A., Rojas-Rueda D., Roy N.K., Ruhago G.M., Sunguya B.F., Saha S., Sahathevan R., Saleh M.M., Sanabria J.R., Sanchez-Nino M.D., Sanchez-Riera L., Sarmiento-Suarez R., Sawhney M., Schaub M.P., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaddick G., Shaheen A., Shahraz S., Shaikh M.A., Sharma R., Shetty B.P., Shin M., Shiri R., Sigfusdottir I.D., Silveira D.G.A., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Singh V., Soneji S., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stathopoulou V., Stein M.B., Stranges S., Stroumpoulis K., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Takala J.S., Talongwa R.T., Taye B., Ten Have M., Tuzcu E.M., Thomson A.J., Thurston G.D., Topor-Madry R., Topouzis F., Towbin J.A., Traebert J., Truelsen T., Trujillo U., Uchendu U.S., Ukwaja K.N., Uthman O.A., Van Dingenen R., van Donkelaar A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Vidavalur R., Violante F.S., Vlassov V.V., Wallin M.T., Weichenthal S., White R.A., Williams H.C., Wong J.Q., Woolf A.D., Xavier D., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Yonga G., Younis M.Z., Zaidi Z., Zaki M.E., Zannad F., Zavala D.E., Zeeb H., Zonies D., Zuhlke L.J., Brown A., Brown J., Singh A., Thrift A.G., Wang L., Wang H., Naghavi M., Allen C., Barber R.M., Carter A., Casey D.C., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Dandona L., Dicker D.J., Erskine H.E., Fitzmaurice C., Foreman K., Forouzanfar M.H., Fraser M.S., Fullman N., Goldberg E.M., Graetz N., Haagsma J.A., Hay S.I., Huynh C., Johnson C.O., Kassebaum N.J., Kulikoff X.R., Kutz M., Kyu H.H., Larson H.J., Leung J., Lim S.S., Lind M., Lozano R., Marquez N., Mikesell J., Mokdad A.H., Mooney M.D., Nguyen G., Nsoesie E., Pigott D.M., Pinho C., Roth G.A., Sandar L., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J., Steiner C., Teeple S., Thomas B.A., Troeger C., VanderZanden A., Vollset S.E., Wanga V., Whiteford H.A., Wolock T., Zoeckler L., Achoki T., Afshin A., Alexander L.T., Anderson G.M., Bell B., Biryukov S., Blore J.D., Cercy K., Chew A., Cohen A.J., Daoud F., Dossou E., Estep K., Flaxman A., Friedman J., Frostad J., Godwin W.W., Hancock J., Kemmer L., Khalil I.A., Liu P.Y., Masiye F., Millear A., Mirarefin M., Misganaw A., Moradi-Lakeh M., Morgan K., Ng M., Pain A., Quame-Amaglo J., Rao P., Reitsma M.B., Shackelford K.A., Sur P., Wagner J.A., Vos T., Lopez A.D., Murray C.J.L., Ellenbogen R.G., Mock C.N., Quistberg D.A., Anderson B.O., Blosser C.D., 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G.Y., Aregay A.F., Betsu B.D., Gebru A.A., Hailu G.B., Yalew A.Z., Yebyo H.G., Abreu D.M.X., Franca E.B., Abu-Raddad L.J., Adelekan A.L., Akinyemi R.O., Ojelabi F.A., Ademi Z., Furst T., Azzopardi P., Cowie B.C., Gibney K.B., MacLachlan J.H., Meretoja A., Alam K., Colquhoun S.M., Patton G.C., Weintraub R.G., Szoeke C.E.I., Vijayakumar L., Bohensky M.A., Taylor H.R., Wijeratne T., Adou A.K., Adsuar J.C., Afanvi K.A., Agardh E.E., Rehm J., Badawi A., Lindsay M.P., Popova S., Agarwal A., Agrawal A., Hotez P.J., Ahmad Kiadaliri A., Norrving B., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al Lami F.H., Alabed S., Al-Aly Z., Driscoll T.R., Leigh J., Kemp A.H., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Aldridge R.W., Banerjee A., Tillmann T., Alegretti M.A., Aleman A.V., Cavalleri F., Colistro V., Alemu Z.A., Alkerwi A., Alla F., Allebeck P., Carrero J.J., Fereshtehnejad S., Weiderpass E., Havmoeller R., Al-Raddadi R., Alsharif U., Alvarez Martin E., Alvis-Guzman N., Amare A.T., Ciobanu L.G., Tessema G.A., Amegah A.K., Kudom A.A., Ameh E.A., Amini H., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Faraon E.J.A., Arnlov J., Larsson A., Arsic Arsenijevic V.S., Barac A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Gankpe F.G., Awasthi A., Bacha U., Bahit M.C., Balakrishnan K., Barker-Collo S.L., Mohammed S., Barregard L., Petzold M., Barrero L.H., Basu A., Basu S., Bayou Y.T., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Deribe K., Belay H.A., Giref A.Z., Haile D., Jibat T., Manamo W.A.A., Tefera W.M., Yirsaw B.D., Sheth K.N., Bell M.L., Biroscak B.J., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D.A., Bernabe E., Beyene A.S., Gishu M.D., Bhala N., Bhalla A., Biadgilign S., Bikbov B., Bin Abdulhak A.A., Bjertness E., Htet A.S., Bose D., Bourne R.R.A., Brainin M., Brayne C.E.G., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Brenner H., Schottker B., Brewer J.D., Brugha T.S., Buckle G.C., Gosselin R.A., Butt Z.A., Calabria B., Lal A., Lucas R.M., Degenhardt L., Resnikoff S., Carapetis J.R., Cardenas R., Carpenter D.O., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cerda J., Chen W., Chiang P.P., Chibalabala M., Chibueze C.E., Mori R., Chimed-Ochir O., Jiang Y., Takahashi K., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Christopher D.J., Cirillo M., Colomar M., Cooper L.T., Crump J.A., Poulton R.G., Damsere-Derry J., Danawi H., Refaat A.H., Dargan P.I., das Neves J., Massano J., Pedro J.M., Davey G., Davis A.C., Greaves F., Newton J.N., Davitoiu D.V., de Castro E.F., de Jager P., De D., Dellavalle R.P., Dharmaratne S.D., Dhillon P.K., Ganguly P., Lal D.K., Zodpey S., Diaz-Torne C., dos Santos K.P.B., Dubey M., Rahman M.H.U., Duncan B.B., Kieling C., Schmidt M.I., Elyazar I., Endries A.Y., Ermakov S.P., Eshrati B., Esteghamati A., Hafezi-Nejad N., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Farzadfar F., Kasaeian A., Parsaeian M., Heydarpour P., Rahimi-Movaghar V., Sheikhbahaei S., Yaseri M., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Te Ao B.J., Fernandes J.G., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franklin R.C., Piel F.B., Majeed A., Gall S.L., Gambashidze K., Gamkrelidze A., Kereselidze M., Shakh-Nazarova M., Iyer V.J., Gebre T., Geleijnse J.M., Gessner B.D., Ghoshal A.G., Gillum R.F., Mehari A., Gilmour S., Inoue M., Kawakami N., Shibuya K., Giroud M., Glaser E., Halasa Y.A., Shepard D.S., Undurraga E.A., Gona P., Goodridge A., Gopalani S.V., Gotay C.C., Kissoon N., Kopec J.A., Murthy S., Pourmalek F., Goto A., Gugnani H.C., Gupta R., Gupta V., Gutierrez R.A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Norman P.E., Hao Y., Harikrishnan S., Haro J.M., Hilderink H.B., Hoek H.W., Tura A.K., Hogg R.S., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Htike M.M.T., Hu G., Huang C., Huang H., Huiart L., Husseini A., Huybrechts I., Huynh G., Iburg K.M., Innos K., Jacobs T.A., Jacobsen K.H., Jahanmehr N., Katibeh M., Rajavi Z., Jakovljevic M.B., Javanbakht M., Jayaraman S.P., Jayatilleke A.U., Prabhakaran D., Jiang G., Jimenez-Corona A., Jonas J.B., Joshi T.K., Kabir Z., Kamal R., Kesavachandran C.N., She J., Shen Z., Zhang H., Kan H., Kant S., Karch A., Karimkhani C., Karletsos D., Karthikeyan G., Naik N., Paul V.K., Roy A., Sagar R., Satpathy M., Tandon N., Kaul A., Kayibanda J.F., Keiyoro P.N., Lyons R.A., Parry C.D., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khang Y.H., Won S., Khera S., Tavakkoli M., Khoja T.A.M., Kim D., Kim Y.J., Kissela B.M., Kokubo Y., Kolte D., McGarvey S.T., Kosen S., Koul P.A., Koyanagi A., Kuate Defo B., Kucuk Bicer B., Kuipers E.J., Kulkarni V.S., Kwan G.F., Rao S.R., Lam H., Lam J.O., Nachega J.B., Tran B.X., Lansingh V.C., Laryea D.O., Latif A.A., Lawrynowicz A.E.B., Levi M., Li Y., Alhabib S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Xiao Q., Lo L., Logroscino G., Lunevicius R., Ma S., Machado V.M., Mackay M.T., Magdy Abd El Razek H., Magdy Abd El Razek M., Mandisarisa J., Mangalam S., Marcenes W., Meaney P.A., Margolis D.J., Silberberg D.H., Martin G.R., Martinez-Raga J., Marzan M.B., Mason-Jones A.J., McMahon B.J., Mehndiratta M.M., Woldeyohannes S.M., Tedla B.A., Zeleke B.M., Memiah P., Memish Z.A., Mendoza W., Meretoja T.J., Lallukka T., Mhimbira F.A., Micha R., Mozaff D., Shi P., Singh G.M., Miller T.R., Mohammad K.A., Mohammadi A., Mohan V., Mola G.L.D., Monasta L., Montico M., Ronfani L., Morawska L., Werdecker A., Mueller U.O., Westerman R., Musa K.I., Paternina Caicedo A.J., Seedat S., Nagel G., Rothenbacher D., Naidoo K.S., Sartorius B., Naldi L., Remuzzi G., Nangia V., Nash D., Nejjari C., Neupane S., Newton C.R., Ngalesoni F.N., Ngirabega J.D., Nguyen Q.L., Nkamedjie Pete P.M., Nomura M., Nyakarahuka L., Ogbo F.A., Ohkubo T., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Ozdemir R., Mahesh P.A., Pandian J.D., Pant P.R., Papachristou C., Park E., Park J., Patten S.B., Tonelli M., Stokic Pejin L., Pereira D.M., Cortinovis M., Giussani G., Perico N., Pesudovs K., Pillay J.D., Plass D., Platts-Mills J.A., Polinder S., Pope C.A., Qorbani M., Rafay A., Rana S.M., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rakovac I., Ranabhat C.L., Rangaswamy T., Ribeiro A.L., Ricci S., Roca A., Rojas-Rueda D., Roy N.K., Ruhago G.M., Sunguya B.F., Saha S., Sahathevan R., Saleh M.M., Sanabria J.R., Sanchez-Nino M.D., Sanchez-Riera L., Sarmiento-Suarez R., Sawhney M., Schaub M.P., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaddick G., Shaheen A., Shahraz S., Shaikh M.A., Sharma R., Shetty B.P., Shin M., Shiri R., Sigfusdottir I.D., Silveira D.G.A., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Singh V., Soneji S., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stathopoulou V., Stein M.B., Stranges S., Stroumpoulis K., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Takala J.S., Talongwa R.T., Taye B., Ten Have M., Tuzcu E.M., Thomson A.J., Thurston G.D., Topor-Madry R., Topouzis F., Towbin J.A., Traebert J., Truelsen T., Trujillo U., Uchendu U.S., Ukwaja K.N., Uthman O.A., Van Dingenen R., van Donkelaar A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Vidavalur R., Violante F.S., Vlassov V.V., Wallin M.T., Weichenthal S., White R.A., Williams H.C., Wong J.Q., Woolf A.D., Xavier D., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Yonga G., Younis M.Z., Zaidi Z., Zaki M.E., Zannad F., Zavala D.E., Zeeb H., Zonies D., Zuhlke L.J., Brown A., Brown J., Singh A., Thrift A.G., Wang L., Wang H., Naghavi M., Allen C., Barber R.M., Carter A., Casey D.C., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Dandona L., Dicker D.J., Erskine H.E., Fitzmaurice C., Foreman K., Forouzanfar M.H., Fraser M.S., Fullman N., Goldberg E.M., Graetz N., Haagsma J.A., Hay S.I., Huynh C., Johnson C.O., Kassebaum N.J., Kulikoff X.R., Kutz M., Kyu H.H., Larson H.J., Leung J., Lim S.S., Lind M., Lozano R., Marquez N., Mikesell J., Mokdad A.H., Mooney M.D., Nguyen G., Nsoesie E., Pigott D.M., Pinho C., Roth G.A., Sandar L., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J., Steiner C., Teeple S., Thomas B.A., Troeger C., VanderZanden A., Vollset S.E., Wanga V., Whiteford H.A., Wolock T., Zoeckler L., Achoki T., Afshin A., Alexander L.T., Anderson G.M., Bell B., Biryukov S., Blore J.D., Cercy K., Chew A., Cohen A.J., Daoud F., Dossou E., Estep K., Flaxman A., Friedman J., Frostad J., Godwin W.W., Hancock J., Kemmer L., Khalil I.A., Liu P.Y., Masiye F., Millear A., Mirarefin M., Misganaw A., Moradi-Lakeh M., Morgan K., Ng M., Pain A., Quame-Amaglo J., Rao P., Reitsma M.B., Shackelford K.A., Sur P., Wagner J.A., Vos T., Lopez A.D., Murray C.J.L., Ellenbogen R.G., Mock C.N., Quistberg D.A., Anderson B.O., Blosser C.D., Futran N.D., Heckbert S.R., Jensen P.N., Montine T.J., Tirschwell D.L., Watkins D.A., Bhutta Z.A., Nisar M.I., Akseer N., Alam N.K.M., Knibbs L.D., Lalloo R., Gouda H.N., McGrath J.J., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Cooper C., Darby S.C., Deribew A., Ali R., Bennett D.A., Jha V., Rahimi K., Kinfu Y., Faghmous I.D.A., Langan S.M., McKee M., Murthy G.V.S., Pearce N., Roberts B., Campos-Nonato I.R., Campuzano J.C., Gomez-Dantes H., Heredia-Pi I.B., Mejia-Rodriguez F., Montanez Hernandez J.C., Montero P., Rios Blancas M.J., Servan-Mori E.E., Villalpando S., Duan L., Liu S., Ye P., Liang X., Yu S., Mensah G.A., Salomon J.A., Thorne-Lyman A.L., Ajala O.N., Barnighausen T., Ding E.L., Farvid M.S., Wagner G.R., James P., Osman M., Shrime M.G., Fitchett J.R.A., Knudsen A.K., Ellingsen C.L., Krog N.H., Savic M., Hailu A.D., Norheim O.F., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abera S.F., Alasfoor D., Melaku Y.A., Tesfay F.H., Abyu G.Y., Aregay A.F., Betsu B.D., Gebru A.A., Hailu G.B., Yalew A.Z., Yebyo H.G., Abreu D.M.X., Franca E.B., Abu-Raddad L.J., Adelekan A.L., Akinyemi R.O., Ojelabi F.A., Ademi Z., Furst T., Azzopardi P., Cowie B.C., Gibney K.B., MacLachlan J.H., Meretoja A., Alam K., Colquhoun S.M., Patton G.C., Weintraub R.G., Szoeke C.E.I., Vijayakumar L., Bohensky M.A., Taylor H.R., Wijeratne T., Adou A.K., Adsuar J.C., Afanvi K.A., Agardh E.E., Rehm J., Badawi A., Lindsay M.P., Popova S., Agarwal A., Agrawal A., Hotez P.J., Ahmad Kiadaliri A., Norrving B., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al Lami F.H., Alabed S., Al-Aly Z., Driscoll T.R., Leigh J., Kemp A.H., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Aldridge R.W., Banerjee A., Tillmann T., Alegretti M.A., Aleman A.V., Cavalleri F., Colistro V., Alemu Z.A., Alkerwi A., Alla F., Allebeck P., Carrero J.J., Fereshtehnejad S., Weiderpass E., Havmoeller R., Al-Raddadi R., Alsharif U., Alvarez Martin E., Alvis-Guzman N., Amare A.T., Ciobanu L.G., Tessema G.A., Amegah A.K., Kudom A.A., Ameh E.A., Amini H., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Faraon E.J.A., Arnlov J., Larsson A., Arsic Arsenijevic V.S., Barac A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Gankpe F.G., Awasthi A., Bacha U., Bahit M.C., Balakrishnan K., Barker-Collo S.L., Mohammed S., Barregard L., Petzold M., Barrero L.H., Basu A., Basu S., Bayou Y.T., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Deribe K., Belay H.A., Giref A.Z., Haile D., Jibat T., Manamo W.A.A., Tefera W.M., Yirsaw B.D., Sheth K.N., Bell M.L., Biroscak B.J., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D.A., Bernabe E., Beyene A.S., Gishu M.D., Bhala N., Bhalla A., Biadgilign S., Bikbov B., Bin Abdulhak A.A., Bjertness E., Htet A.S., Bose D., Bourne R.R.A., Brainin M., Brayne C.E.G., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Brenner H., Schottker B., Brewer J.D., Brugha T.S., Buckle G.C., Gosselin R.A., Butt Z.A., Calabria B., Lal A., Lucas R.M., Degenhardt L., Resnikoff S., Carapetis J.R., Cardenas R., Carpenter D.O., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cerda J., Chen W., Chiang P.P., Chibalabala M., Chibueze C.E., Mori R., Chimed-Ochir O., Jiang Y., Takahashi K., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Christopher D.J., Cirillo M., Colomar M., Cooper L.T., Crump J.A., Poulton R.G., Damsere-Derry J., Danawi H., Refaat A.H., Dargan P.I., das Neves J., Massano J., Pedro J.M., Davey G., Davis A.C., Greaves F., Newton J.N., Davitoiu D.V., de Castro E.F., de Jager P., De D., Dellavalle R.P., Dharmaratne S.D., Dhillon P.K., Ganguly P., Lal D.K., Zodpey S., Diaz-Torne C., dos Santos K.P.B., Dubey M., Rahman M.H.U., Duncan B.B., Kieling C., Schmidt M.I., Elyazar I., Endries A.Y., Ermakov S.P., Eshrati B., Esteghamati A., Hafezi-Nejad N., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Farzadfar F., Kasaeian A., Parsaeian M., Heydarpour P., Rahimi-Movaghar V., Sheikhbahaei S., Yaseri M., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Te Ao B.J., Fernandes J.G., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franklin R.C., Piel F.B., Majeed A., Gall S.L., Gambashidze K., Gamkrelidze A., Kereselidze M., Shakh-Nazarova M., Iyer V.J., Gebre T., Geleijnse J.M., Gessner B.D., Ghoshal A.G., Gillum R.F., Mehari A., Gilmour S., Inoue M., Kawakami N., Shibuya K., Giroud M., Glaser E., Halasa Y.A., Shepard D.S., Undurraga E.A., Gona P., Goodridge A., Gopalani S.V., Gotay C.C., Kissoon N., Kopec J.A., Murthy S., Pourmalek F., Goto A., Gugnani H.C., Gupta R., Gupta V., Gutierrez R.A., Hamadeh R.R., Hamidi S., Handal A.J., Hankey G.J., Norman P.E., Hao Y., Harikrishnan S., Haro J.M., Hilderink H.B., Hoek H.W., Tura A.K., Hogg R.S., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hsairi M., Htike M.M.T., Hu G., Huang C., Huang H., Huiart L., Husseini A., Huybrechts I., Huynh G., Iburg K.M., Innos K., Jacobs T.A., Jacobsen K.H., Jahanmehr N., Katibeh M., Rajavi Z., Jakovljevic M.B., Javanbakht M., Jayaraman S.P., Jayatilleke A.U., Prabhakaran D., Jiang G., Jimenez-Corona A., Jonas J.B., Joshi T.K., Kabir Z., Kamal R., Kesavachandran C.N., She J., Shen Z., Zhang H., Kan H., Kant S., Karch A., Karimkhani C., Karletsos D., Karthikeyan G., Naik N., Paul V.K., Roy A., Sagar R., Satpathy M., Tandon N., Kaul A., Kayibanda J.F., Keiyoro P.N., Lyons R.A., Parry C.D., Kengne A.P., Matzopoulos R., Wiysonge C.S., Stein D.J., Mayosi B.M., Keren A., Khader Y.S., Khan E.A., Khang Y.H., Won S., Khera S., Tavakkoli M., Khoja T.A.M., Kim D., Kim Y.J., Kissela B.M., Kokubo Y., Kolte D., McGarvey S.T., Kosen S., Koul P.A., Koyanagi A., Kuate Defo B., Kucuk Bicer B., Kuipers E.J., Kulkarni V.S., Kwan G.F., Rao S.R., Lam H., Lam J.O., Nachega J.B., Tran B.X., Lansingh V.C., Laryea D.O., Latif A.A., Lawrynowicz A.E.B., Levi M., and Li Y.

Abstract

Background Improving survival and extending the longevity of life for all populations requires timely, robust evidence on local mortality levels and trends. The Global Burden of Disease 2015 Study (GBD 2015) provides a comprehensive assessment of all-cause and cause-specific mortality for 249 causes in 195 countries and territories from 1980 to 2015. These results informed an in-depth investigation of observed and expected mortality patterns based on sociodemographic measures. Methods We estimated all-cause mortality by age, sex, geography, and year using an improved analytical approach originally developed for GBD 2013 and GBD 2010. Improvements included refinements to the estimation of child and adult mortality and corresponding uncertainty, parameter selection for under-5 mortality synthesis by spatiotemporal Gaussian process regression, and sibling history data processing. We also expanded the database of vital registration, survey, and census data to 14 294 geography-year datapoints. For GBD 2015, eight causes, including Ebola virus disease, were added to the previous GBD cause list for mortality. We used six modelling approaches to assess cause-specific mortality, with the Cause of Death Ensemble Model (CODEm) generating estimates for most causes. We used a series of novel analyses to systematically quantify the drivers of trends in mortality across geographies. First, we assessed observed and expected levels and trends of cause-specific mortality as they relate to the Socio-demographic Index (SDI), a summary indicator derived from measures of income per capita, educational attainment, and fertility. Second, we examined factors affecting total mortality patterns through a series of counterfactual scenarios, testing the magnitude by which population growth, population age structures, and epidemiological changes contributed to shifts in mortality. Finally, we attributed changes in life expectancy to changes in cause of death. We documented each step of the GBD 2

Published
2016

29. Measuring the health-related Sustainable Development Goals in 188 countries: a baseline analysis from the Global Burden of Disease Study 2015.

Author

Nguhiu P., Shigematsu M., Shin M., Yoon S., Shiri R., Shishani K., Sigfusdottir I.D., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stahl H., Stathopoulou V., Steckling N., Stranges S., Strong M., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Talongwa R.T., Tarawneh M.R., Tavakkoli M., Taye B., Tuzcu E.M., Thakur J., Thomson A.J., Thurston G.D., Tobe-Gai R., Topor-Madry R., Topouzis F., Tsala Dimbuene Z., Tyrovolas S., Ukwaja K.N., Uneke C.J., Uthman O.A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Violante F.S., Vlassov V.V., Volkow P., Wallin M.T., Weichenthal S., Woolf A.D., Wubshet M., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Younis M.Z., Yu C., Zaidi Z., Zaki M.E., Zambrana-Torrelio C., Zapata T., Zonies D., Singh A., Thrift A.G., Wang L., Lim S.S., Allen K., Dandona L., Forouzanfar M.H., Fullman N., Goldberg E.M., Hay S.I., Holmberg M., Kutz M.J., Larson H.J., Lopez A.D., McNellan C.R., Mokdad A.H., Mooney M.D., Naghavi M., Olsen H.E., Pigott D.M., Vos T., Wang H., Achoki T., Afshin A., Allen C., Anderson G.M., Barber R., Bienhoff K.A., Blore J., Brauer M., Carter A., Casey D., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Cohen A.J., Deshpande A., Erskine H.E., Ferrari A.J., Fitzmaurice C., Foreman K., Fraser M., Friedman J., Frostad J., Godwin W., Graetz N., Griswold M., Haagsma J.A., Haakenstad A., Kassebaum N.J., Kemmer L., Kulikoff X.R., Kyu H.H., Leung J., Lind M., Liu P.Y., Masiye F., Mirarefin M., Misganaw A., Moradi-Lakeh M., Nguyen G., Pinho C., Rao P.C., Reitsma M.B., Roth G.A., Santomauro D.F., Shackelford K., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J.D., Steiner C., Sur P., Vollset S.E., Wanga V., Whiteford H.A., Zhao Y., Zhou M., Murray C.J.L., Kotsakis G.A., Mock C.N., Anderson B.O., Watkins D.A., Bhutta Z.A., Nisar M.I., Akseer N., deVeber G.A., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Bisanzio D., Cooper C., Ali R., Bennett D.A., Jha V., Weiss D.J., Kinfu Y., Patel V., Langan S.M., McKee M., Murthy G.V.S., Roberts B., Stockl H., Duan L., Jin Y., Li Y., Liu S., Ye P., Liang X., Azzopardi P., Cowie B.C., Meretoja A., Patton G.C., Alam K., Weintraub R.G., Sawyer S.M., Szoeke C.E.I., Taylor H.R., Lozano R., Barrientos-Gutierrez T., Campos-Nonato I.R., Campuzano J.C., Heredia-Pi I.B., Montanez Hernandez J.C., Rios Blancas M.J., Servan-Mori E.E., Shamah Levy T., Salomon J.A., Binagwaho A., Barnighausen T., Cahill L.E., Ding E.L., Farvid M.S., Wagner G.R., Thorne-Lyman A.L., James P., Fitchett J.R.A., Abajobir A.A., Knibbs L.D., Veerman J.L., Lalloo R., Gouda H.N., Guo Y., McGrath J.J., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abraham B., Abubakar I., Aldridge R.W., Banerjee A., Benzian H., Tillmann T., Abu-Raddad L.J., Abu-Rmeileh N.M., Melaku Y.A., Abyu G.Y., Bayou T.A., Betsu B.D., Gebru A.A., Hailu G.B., Tekle D.Y., Yalew A.Z., Adebiyi A.O., Owolabi M.O., Akinyemi R.O., Adedeji I.A., Afanvi K.A., Micha R., Shi P., Singh G.M., Badawi A., Agarwal A., Agrawal A., Ahmad Kiadaliri A., Norrving B., Ahmadieh H., Yaseri M., Jahanmehr N., Ahmed K.Y., Alemu Z.A., Tegegne T.K., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al-Aly Z., Driscoll T.R., Leigh J., Mekonnen A.B., Neal B., Alam U., Alasfoor D., AlBuhairan F.S., Alkhateeb M.A., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Alkerwi A., Alla F., Allebeck P., Rabiee R.H.S., Roy N., Kivipelto M., Carrero J.J., Fereshtehnejad S.M., Weiderpass E., Havmoeller R., Sindi S., Al-Raddadi R., Alvarez E., Alvis-Guzman N., Paternina Caicedo A.J., Amare A.T., Ciobanu L.G., Tessema G.A., Amberbir A., Amegah A.K., Amini H., Furst T., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Anwari P., Arnlov J., Larsson A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Awasthi A., Ayala Quintanilla B.P., Bacha U., Balakrishnan K., Barac A., Barker-Collo S.L., Mohammed S., Barrero L.H., Basu S., Del L.C., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Bejot Y., Sheth K.N., Bell M.L., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D., Bernabe E., Wolfe I., Bernal O.A., Roba H.S., Beyene A.S., Mesfin Y.M., Bhala N., Bhatt S., Biadgilign S., Bikbov B., Soneji S., Bjertness E., Htet A.S., Bourne R.R.A., Brainin M., Krueger H., Gotay C.C., Kissoon N., Murthy S., Pourmalek F., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Broday D.M., Brugha T.S., Buchbinder R., Gabbe B., Butt Z.A., van Donkelaar A., Martin R.V., Carabin H., Cardenas R., Caso V., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cavalleri F., Cecilio P., das Neves J., Massano J., Pedro J.M., Chang H., Chang J., Che X., Chiang P.P., Chibalabala M., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Cirillo M., Piel F.B., Rodriguez A., Cooke G.S., Majeed A., Cooper L.T., Crump J.A., Derrett S., Poulton R.G., Damtew S.A., Workie S.B., Deribe K., Tefera W., Giref A.Z., Haile D., Temam Shifa G., Dargan P.I., Davis A.C., Newton J.N., Steel N., Davletov K., de Castro E.F., De Leo D., Degenhardt L., Resnikoff S., Mitchell P.B., Des Jarlais D.C., Dey S., Dhillon P.K., Lal D.K., Zodpey S., Dharmaratne S.D., Dorsey E.R., Doyle K.E., Kemp A.H., Dubey M., Rahman M.H.U., Ram U., Verma R.K., Yadav A.K., Duncan B.B., Kieling C., Schmidt M.I., Ebrahimi H., Esteghamati A., Farzadfar F., Hafezi-Nejad N., Kasaeian A., Parsaeian M., Pishgar F., Sheikhbahaei S., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Hassanvand M.S., Khosravi A., Rahimi-Movaghar V., Endries A.Y., Ermakov S.P., Soshnikov S., Eshrati B., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Felicio M.M., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franca E.B., Franklin R.C., Garcia-Basteiro A.L., Gebre T., Gessner B.D., Gillum R.F., Mehari A., Ginawi I.A., Giroud M., Gishu M.D., Tura A.K., Gona P., Goodridge A., Gopalani S.V., Goto A., Inoue M., Greenwell K.F., Gupta R., Gupta V., Gutierrez R.A., Gyawali B., Iburg K.M., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Hammami M., Hankey G.J., Haro J.M., Hoek H.W., Skirbekk V., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hu G., Huang H., Idrisov B.T., Kwan G.F., Kawakami N., Shibuya K., Islami F., Jacobs T.A., Jacobsen K.H., Jakovljevic M.B., Jansen H.A.F., Javanbakht M., Jayatilleke A.U., Jee S.H., Jiang Y., Jibat T., Jonas J.B., Kabir Z., Kalkonde Y., Kamal R., Kesavachandran C.N., She J., Kan H., Kandel A., Karch A., Karimkhani C., Karunapema P., Kaul A., Kayibanda J.F., Keiyoro P.N., Matzopoulos R., Parry C.D., Kengne A.P., Wiysonge C.S., Stein D.J., Mayosi B.M., Shey M., Keren A., Khader Y.S., Khan E.A., Khan G., Khang Y.H., Won S., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kim S., Kim Y.J., Kimokoti R.W., Kokubo Y., Kolte D., Kosen S., Koul P.A., Koyanagi A., Kravchenko M., Varakin Y.Y., Kuate Defo B., Kuchenbecker R.S., Kuipers E.J., Kulkarni V.S., Lal A., Lucas R.M., Lam H., Lan Q., Laryea D.O., Latif A.A., Leasher J.L., Leinsalu M., Leung R., Levi M., Linn S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Lloyd B.K., Lo L., Logroscino G., Lunevicius R., Magdy M., Magis-Rodriguez C., Mahdavi M., Malta D.C., Meaney P.A., Margolis D.J., Martinez-Raga J., Mason-Jones A.J., Tedla B.A., Memiah P., Memish Z.A., Mendoza W., Mensink G.B.M., Meretoja T.J., Mhimbira F.A., Miller T.R., Mills E.J., Mohammadi A., Monasta L., Montico M., Ronfani L., Monis J.D., Morawska L., Sun J., Mori R., Werdecker A., Mueller U.O., Westerman R., Murdoch M.E., Murimira B., Murray J., Musa K.I., Nachega J.B., Seedat S., Tran B.X., Nagel G., Rothenbacher D., Naidoo K.S., Oladimeji O., Sartorius B., Zegeye E.A., Naldi L., Remuzzi G., Nangia V., Nejjari C., Newton C.R., Ngalesoni F.N., Nguyen Q.L., Nkamedjie P.M., Nolte S., Osborne R.H., Nomura M., Norheim O.F., Obermeyer C.M., Ogbo F.A., Oh I., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Mahesh P.A., Park E., Park H., Patel T., Patil S.T., Patten S.B., Tonelli M., Paudel D., Pereira D.M., Perico N., Pesudovs K., Petzold M., Pillay J.D., Polinder S., Qorbani M., Radfar A., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rana S.M., Ranabhat C.L., Ranganathan K., Refaat A.H., Ribeiro A.L., Rojas-Rueda D., Roy A., Sagar R., Satpathy M., Sackey B.B., Saleh M.M., Sanabria J.R., Sarmiento-Suarez R., Savic M., Sawhney M., Schmidhuber J., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaheen A., Shaikh M.A., Sharma R., Nguhiu P., Shigematsu M., Shin M., Yoon S., Shiri R., Shishani K., Sigfusdottir I.D., Silverberg J.I., Yano Y., Singh O.P., Singh P.K., Soreide K., Soriano J.B., Sposato L.A., Sreeramareddy C.T., Stahl H., Stathopoulou V., Steckling N., Stranges S., Strong M., Sunguya B.F., Swaminathan S., Sykes B.L., Tabares-Seisdedos R., Tabb K.M., Talongwa R.T., Tarawneh M.R., Tavakkoli M., Taye B., Tuzcu E.M., Thakur J., Thomson A.J., Thurston G.D., Tobe-Gai R., Topor-Madry R., Topouzis F., Tsala Dimbuene Z., Tyrovolas S., Ukwaja K.N., Uneke C.J., Uthman O.A., Vasankari T., Vasconcelos A.M.N., Venketasubramanian N., Violante F.S., Vlassov V.V., Volkow P., Wallin M.T., Weichenthal S., Woolf A.D., Wubshet M., Xu G., Yakob B., Yan L.L., Yip P., Yonemoto N., Younis M.Z., Yu C., Zaidi Z., Zaki M.E., Zambrana-Torrelio C., Zapata T., Zonies D., Singh A., Thrift A.G., Wang L., Lim S.S., Allen K., Dandona L., Forouzanfar M.H., Fullman N., Goldberg E.M., Hay S.I., Holmberg M., Kutz M.J., Larson H.J., Lopez A.D., McNellan C.R., Mokdad A.H., Mooney M.D., Naghavi M., Olsen H.E., Pigott D.M., Vos T., Wang H., Achoki T., Afshin A., Allen C., Anderson G.M., Barber R., Bienhoff K.A., Blore J., Brauer M., Carter A., Casey D., Charlson F.J., Chen A.Z., Coates M.M., Coggeshall M., Cohen A.J., Deshpande A., Erskine H.E., Ferrari A.J., Fitzmaurice C., Foreman K., Fraser M., Friedman J., Frostad J., Godwin W., Graetz N., Griswold M., Haagsma J.A., Haakenstad A., Kassebaum N.J., Kemmer L., Kulikoff X.R., Kyu H.H., Leung J., Lind M., Liu P.Y., Masiye F., Mirarefin M., Misganaw A., Moradi-Lakeh M., Nguyen G., Pinho C., Rao P.C., Reitsma M.B., Roth G.A., Santomauro D.F., Shackelford K., Silpakit N., Sligar A., Sorensen R.J.D., Stanaway J.D., Steiner C., Sur P., Vollset S.E., Wanga V., Whiteford H.A., Zhao Y., Zhou M., Murray C.J.L., Kotsakis G.A., Mock C.N., Anderson B.O., Watkins D.A., Bhutta Z.A., Nisar M.I., Akseer N., deVeber G.A., Jeemon P., Dandona R., Kumar G.A., Gething P.W., Bisanzio D., Cooper C., Ali R., Bennett D.A., Jha V., Weiss D.J., Kinfu Y., Patel V., Langan S.M., McKee M., Murthy G.V.S., Roberts B., Stockl H., Duan L., Jin Y., Li Y., Liu S., Ye P., Liang X., Azzopardi P., Cowie B.C., Meretoja A., Patton G.C., Alam K., Weintraub R.G., Sawyer S.M., Szoeke C.E.I., Taylor H.R., Lozano R., Barrientos-Gutierrez T., Campos-Nonato I.R., Campuzano J.C., Heredia-Pi I.B., Montanez Hernandez J.C., Rios Blancas M.J., Servan-Mori E.E., Shamah Levy T., Salomon J.A., Binagwaho A., Barnighausen T., Cahill L.E., Ding E.L., Farvid M.S., Wagner G.R., Thorne-Lyman A.L., James P., Fitchett J.R.A., Abajobir A.A., Knibbs L.D., Veerman J.L., Lalloo R., Gouda H.N., Guo Y., McGrath J.J., Abate K.H., Gebrehiwot T.T., Gebremedhin A.T., Abbafati C., Abbas K.M., Abd-Allah F., Abdulle A.M., Abraham B., Abubakar I., Aldridge R.W., Banerjee A., Benzian H., Tillmann T., Abu-Raddad L.J., Abu-Rmeileh N.M., Melaku Y.A., Abyu G.Y., Bayou T.A., Betsu B.D., Gebru A.A., Hailu G.B., Tekle D.Y., Yalew A.Z., Adebiyi A.O., Owolabi M.O., Akinyemi R.O., Adedeji I.A., Afanvi K.A., Micha R., Shi P., Singh G.M., Badawi A., Agarwal A., Agrawal A., Ahmad Kiadaliri A., Norrving B., Ahmadieh H., Yaseri M., Jahanmehr N., Ahmed K.Y., Alemu Z.A., Tegegne T.K., Akanda A.S., Akinyemiju T.F., Schwebel D.C., Singh J.A., Al-Aly Z., Driscoll T.R., Leigh J., Mekonnen A.B., Neal B., Alam U., Alasfoor D., AlBuhairan F.S., Alkhateeb M.A., Aldhahri S.F., Altirkawi K.A., Terkawi A.S., Alkerwi A., Alla F., Allebeck P., Rabiee R.H.S., Roy N., Kivipelto M., Carrero J.J., Fereshtehnejad S.M., Weiderpass E., Havmoeller R., Sindi S., Al-Raddadi R., Alvarez E., Alvis-Guzman N., Paternina Caicedo A.J., Amare A.T., Ciobanu L.G., Tessema G.A., Amberbir A., Amegah A.K., Amini H., Furst T., Karema C.K., Ammar W., Harb H.L., Amrock S.M., Andersen H.H., Antonio C.A.T., Anwari P., Arnlov J., Larsson A., Artaman A., Asayesh H., Asghar R.J., Atique S., Avokpaho E.F.G.A., Awasthi A., Ayala Quintanilla B.P., Bacha U., Balakrishnan K., Barac A., Barker-Collo S.L., Mohammed S., Barrero L.H., Basu S., Del L.C., Bazargan-Hejazi S., Beardsley J., Bedi N., Beghi E., Bejot Y., Sheth K.N., Bell M.L., Bello A.K., Santos I.S., Bensenor I.M., Lotufo P.A., Berhane A., Wolfe C.D., Bernabe E., Wolfe I., Bernal O.A., Roba H.S., Beyene A.S., Mesfin Y.M., Bhala N., Bhatt S., Biadgilign S., Bikbov B., Soneji S., Bjertness E., Htet A.S., Bourne R.R.A., Brainin M., Krueger H., Gotay C.C., Kissoon N., Murthy S., Pourmalek F., Brazinova A., Majdan M., Shen J., Breitborde N.J.K., Broday D.M., Brugha T.S., Buchbinder R., Gabbe B., Butt Z.A., van Donkelaar A., Martin R.V., Carabin H., Cardenas R., Caso V., Castaneda-Orjuela C.A., Castillo Rivas J., Catala-Lopez F., Cavalleri F., Cecilio P., das Neves J., Massano J., Pedro J.M., Chang H., Chang J., Che X., Chiang P.P., Chibalabala M., Chisumpa V.H., Mapoma C.C., Choi J.J., Chowdhury R., Christensen H., Cirillo M., Piel F.B., Rodriguez A., Cooke G.S., Majeed A., Cooper L.T., Crump J.A., Derrett S., Poulton R.G., Damtew S.A., Workie S.B., Deribe K., Tefera W., Giref A.Z., Haile D., Temam Shifa G., Dargan P.I., Davis A.C., Newton J.N., Steel N., Davletov K., de Castro E.F., De Leo D., Degenhardt L., Resnikoff S., Mitchell P.B., Des Jarlais D.C., Dey S., Dhillon P.K., Lal D.K., Zodpey S., Dharmaratne S.D., Dorsey E.R., Doyle K.E., Kemp A.H., Dubey M., Rahman M.H.U., Ram U., Verma R.K., Yadav A.K., Duncan B.B., Kieling C., Schmidt M.I., Ebrahimi H., Esteghamati A., Farzadfar F., Hafezi-Nejad N., Kasaeian A., Parsaeian M., Pishgar F., Sheikhbahaei S., Fahimi S., Malekzadeh R., Roshandel G., Sepanlou S.G., Hassanvand M.S., Khosravi A., Rahimi-Movaghar V., Endries A.Y., Ermakov S.P., Soshnikov S., Eshrati B., Farid T.A., Khan A.R., Farinha C.S.E.S., Faro A., Feigin V.L., Felicio M.M., Fernandes J.C., Fischer F., Foigt N., Shiue I., Fowkes F.G.R., Franca E.B., Franklin R.C., Garcia-Basteiro A.L., Gebre T., Gessner B.D., Gillum R.F., Mehari A., Ginawi I.A., Giroud M., Gishu M.D., Tura A.K., Gona P., Goodridge A., Gopalani S.V., Goto A., Inoue M., Greenwell K.F., Gupta R., Gupta V., Gutierrez R.A., Gyawali B., Iburg K.M., Halasa Y.A., Undurraga E.A., Hamadeh R.R., Hamidi S., Hammami M., Hankey G.J., Haro J.M., Hoek H.W., Skirbekk V., Horino M., Horita N., Hosgood H.D., Hoy D.G., Hu G., Huang H., Idrisov B.T., Kwan G.F., Kawakami N., Shibuya K., Islami F., Jacobs T.A., Jacobsen K.H., Jakovljevic M.B., Jansen H.A.F., Javanbakht M., Jayatilleke A.U., Jee S.H., Jiang Y., Jibat T., Jonas J.B., Kabir Z., Kalkonde Y., Kamal R., Kesavachandran C.N., She J., Kan H., Kandel A., Karch A., Karimkhani C., Karunapema P., Kaul A., Kayibanda J.F., Keiyoro P.N., Matzopoulos R., Parry C.D., Kengne A.P., Wiysonge C.S., Stein D.J., Mayosi B.M., Shey M., Keren A., Khader Y.S., Khan E.A., Khan G., Khang Y.H., Won S., Khoja T.A.M., Khubchandani J., Kim C., Kim D., Kim S., Kim Y.J., Kimokoti R.W., Kokubo Y., Kolte D., Kosen S., Koul P.A., Koyanagi A., Kravchenko M., Varakin Y.Y., Kuate Defo B., Kuchenbecker R.S., Kuipers E.J., Kulkarni V.S., Lal A., Lucas R.M., Lam H., Lan Q., Laryea D.O., Latif A.A., Leasher J.L., Leinsalu M., Leung R., Levi M., Linn S., Lipshultz S.E., Wilkinson J.D., Simard E.P., Liu Y., Phillips M.R., Lloyd B.K., Lo L., Logroscino G., Lunevicius R., Magdy M., Magis-Rodriguez C., Mahdavi M., Malta D.C., Meaney P.A., Margolis D.J., Martinez-Raga J., Mason-Jones A.J., Tedla B.A., Memiah P., Memish Z.A., Mendoza W., Mensink G.B.M., Meretoja T.J., Mhimbira F.A., Miller T.R., Mills E.J., Mohammadi A., Monasta L., Montico M., Ronfani L., Monis J.D., Morawska L., Sun J., Mori R., Werdecker A., Mueller U.O., Westerman R., Murdoch M.E., Murimira B., Murray J., Musa K.I., Nachega J.B., Seedat S., Tran B.X., Nagel G., Rothenbacher D., Naidoo K.S., Oladimeji O., Sartorius B., Zegeye E.A., Naldi L., Remuzzi G., Nangia V., Nejjari C., Newton C.R., Ngalesoni F.N., Nguyen Q.L., Nkamedjie P.M., Nolte S., Osborne R.H., Nomura M., Norheim O.F., Obermeyer C.M., Ogbo F.A., Oh I., Olivares P.R., Olusanya B.O., Olusanya J.O., Opio J.N., Oren E., Ortiz A., Ota E., Mahesh P.A., Park E., Park H., Patel T., Patil S.T., Patten S.B., Tonelli M., Paudel D., Pereira D.M., Perico N., Pesudovs K., Petzold M., Pillay J.D., Polinder S., Qorbani M., Radfar A., Rahman M., Rahman S.U., Rai R.K., Rajsic S., Raju M., Rana S.M., Ranabhat C.L., Ranganathan K., Refaat A.H., Ribeiro A.L., Rojas-Rueda D., Roy A., Sagar R., Satpathy M., Sackey B.B., Saleh M.M., Sanabria J.R., Sarmiento-Suarez R., Savic M., Sawhney M., Schmidhuber J., Schneider I.J.C., Silva D.A.S., Schutte A.E., Shaheen A., Shaikh M.A., and Sharma R.

Abstract

Background In September, 2015, the UN General Assembly established the Sustainable Development Goals (SDGs). The SDGs specify 17 universal goals, 169 targets, and 230 indicators leading up to 2030. We provide an analysis of 33 health-related SDG indicators based on the Global Burden of Diseases, Injuries, and Risk Factors Study 2015 (GBD 2015). Methods We applied statistical methods to systematically compiled data to estimate the performance of 33 health-related SDG indicators for 188 countries from 1990 to 2015. We rescaled each indicator on a scale from 0 (worst observed value between 1990 and 2015) to 100 (best observed). Indices representing all 33 health-related SDG indicators (health-related SDG index), health-related SDG indicators included in the Millennium Development Goals (MDG index), and health-related indicators not included in the MDGs (non-MDG index) were computed as the geometric mean of the rescaled indicators by SDG target. We used spline regressions to examine the relations between the Socio-demographic Index (SDI, a summary measure based on average income per person, educational attainment, and total fertility rate) and each of the health-related SDG indicators and indices. Findings In 2015, the median health-related SDG index was 59.3 (95% uncertainty interval 56.8-61.8) and varied widely by country, ranging from 85.5 (84.2-86.5) in Iceland to 20.4 (15.4-24.9) in Central African Republic. SDI was a good predictor of the health-related SDG index (r2=0.88) and the MDG index (r2=0.92), whereas the non-MDG index had a weaker relation with SDI (r2=0.79). Between 2000 and 2015, the health-related SDG index improved by a median of 7.9 (IQR 5.0-10.4), and gains on the MDG index (a median change of 10.0 [6.7-13.1]) exceeded that of the non-MDG index (a median change of 5.5 [2.1-8.9]). Since 2000, pronounced progress occurred for indicators such as met need with modern contraception, under-5 mortality, and neonatal mortality, as well as the indicator for

Published
2016

30. Global, regional, and national levels of maternal mortality, 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015

Author

Kassebaum, NJ, Barber, RM, Bhutta, ZA, Dandona, L, Gething, PW, Hay, SI, Kinfu, Y, Larson, HJ, Liang, X, Lim, SS, Lopez, AD, Lozano, R, Mensah, GA, Mokdad, AH, Naghavi, M, Pinho, C, Salomon, JA, Steiner, C, Vos, T, Wang, H, Abajobir, AA, Abate, KH, Abbas, KM, Abd-Allah, F, Abdallat, MA, Abdulle, AM, Abera, SF, Aboyans, V, Abubakar, I, Abu-Rmeileh, NME, Achoki, T, Adebiyi, AO, Adedeji, IA, Adelekan, AL, Adou, AK, Afanvi, KA, Agarwal, A, Kiadaliri, AA, Ajala, ON, Akinyemiju, TF, Akseer, N, Al-Aly, Z, Alam, K, Alam, NKM, Alasfoor, D, Aldhahri, SF, Aldridge, RW, Alhabib, S, Ali, R, Alkerwi, A, Alla, F, Al-Raddadi, R, Alsharif, U, Martin, EA, Alvis-Guzman, N, Amare, AT, Amberbir, A, Amegah, AK, Ammar, W, Amrock, SM, Andersen, HH, Anderson, GM, Antoine, RM, Antonio, CAT, Aregay, AF, Arnlov, J, Arora, M, Arsenijevic, VSA, Al, A, Asayesh, H, Atique, S, Avokpaho, EFGA, Awasthi, A, Quintanilla, BPA, Azzopardi, P, Bacha, U, Badawi, A, Bahit, MC, Balakrishnan, K, Banerjee, A, Barac, A, Barker-Collo, SL, Barnighausen, T, Basu, S, Bayou, TA, Bayou, YT, Bazargan-Hejazi, S, Beardsley, J, Bedi, NW, Bekele, T, Bell, ML, Bennett, DA, Bensenor, IM, Berhane, A, Bernabe, E, Betsu, BD, Beyene, AS, Biadgilign, S, Bikbov, B, Bin Abdulhak, AA, Biroscak, BJ, Biryukov, S, Bisanzio, D, Bjertness, E, Blore, JD, Brainin, M, Brazinova, A, Breitborde, NJK, Brugha, TS, Butt, ZA, Campos-Nonato, IR, Campuzano, JC, Cardenas, R, Carrero, JJ, Carter, A, Casey, DC, Castaneda-Oquela, CA, Castro, RE, Catala-Lopez, F, Cavalleri, F, Chang, H-Y, Chang, J-C, Chavan, L, Chibueze, CE, Chisumpa, VH, Choi, J-YJ, Chowdhury, R, Christopher, DJ, Ciobanu, LG, Cirillo, M, Coates, MM, Coggeshall, M, Colistro, V, Colquhoun, SM, Cooper, C, Cooper, LT, Cortinovis, M, Dahiru, T, Damasceno, A, Danawi, H, Dandona, R, Das Neves, J, De Leo, D, Dellavalle, RP, Deribe, K, Deribew, A, Jarlais, DCD, Dharmaratne, SD, Dicker, DJ, Ding, EL, Dossou, E, Dubey, M, Ebel, BE, Ellingsen, CL, Elyazar, I, Endries, AY, Ermakov, SP, Eshrati, B, Esteghamati, A, Faraon, EJA, Farid, TA, Farinha, CSES, Faro, A, Farvid, MS, Farzadfar, F, Fereshtehnejad, S-M, Fernandes, JC, Fischer, F, Fitchett, JRA, Fleming, T, Gt, NF, Franca, EB, Franklin, RC, Fraser, MS, Friedman, J, Pullman, N, Furst, T, Futran, ND, Gambashidze, K, Gamkrelidze, A, Gebre, T, Gebrehiwot, TT, Gebremedhin, AT, Gebremedhin, M, Gebru, AA, Geleijnse, JM, Gibney, KB, Giref, AZ, Giroud, M, Gishu, MD, Glaser, E, Goenka, S, Gomez-Dantes, H, Gona, P, Goodridge, A, Gopalani, SV, Goto, A, Graetz, N, Gugnani, HC, Guo, Y, Gupta, R, Gupta, V, Hafezi-Nejad, N, Hailu, AD, Hailu, GB, Hamadeh, RR, Hamidi, S, Hancock, J, Handal, AJ, Hankey, GJ, Harb, HL, Harikrishnan, S, Harun, KM, Havmoeller, R, Hoek, HW, Horino, M, Horita, N, Hosgood, HD, Hoy, DG, Htet, AS, Hu, G, Huang, H, Huang, JJ, Huybrechts, I, Huynh, C, Iannarone, M, Iburg, KM, Idrisov, BT, Iyer, VJ, Jacobsen, KH, Jahanmehr, N, Jakovljevic, MB, Javanbakht, M, Jayatilleke, AU, Jee, SH, Jeemon, P, Jha, V, Jiang, G, Jiang, Y, Jibat, T, Jonas, JB, Kabir, Z, Kamal, R, Kan, H, Karch, A, Karletsos, D, Kasaeian, A, Kaul, A, Kawakami, N, Kayibanda, JF, Kazanjan, K, Kazi, DS, Keiyoro, PN, Kemmer, L, Kemp, AH, Kengne, AP, Keren, A, Kereselidze, M, Kesavachandran, CN, Khader, YS, Khan, AR, Khan, EA, Khang, Y-H, Khonelidze, I, Khosravi, A, Khubchandani, J, Kim, YJ, Kivipelto, M, Knibbs, LD, Kokubo, Y, Kosen, S, Koul, PA, Koyanagi, A, Krishnaswami, S, Defo, BK, Bicer, BK, Kudom, AA, Kulikoff, XR, Kulkarni, C, Kumar, GA, Kutz, MJ, Lal, DK, Lalloo, R, Lam, H, Lamadrid-Figueroa, H, Lan, Q, Larsson, A, Laryea, DO, Leigh, J, Leung, R, Li, Y, Lipshultz, SE, Liu, PY, Liu, S, Liu, Y, Lloyd, BK, Lotufo, PA, Lunevicius, R, Ma, S, El Razek, HMA, El Razek, MMA, Majdan, M, Majeed, A, Malekzadeh, R, Mapoma, CC, Marcenes, W, Margolis, DJ, Marquez, N, Masiye, F, Marzan, MB, Mason-Jones, AJ, Mazorodze, TT, Meaney, PA, Mehari, A, Mehndiratta, MM, Mena-Rodriguez, F, Mekonnen, AB, Melaku, YA, Memish, ZA, Mendoza, W, Meretoja, A, Meretoja, TJ, Mhimbira, FA, Miller, TR, Mills, EJ, Mirarefin, M, Misganaw, A, Ibrahim, NM, Mohammad, KA, Mohammadi, A, Mohammed, S, Mola, GLD, Monasta, L, Monis, JDLC, Hernandez, JCM, Montero, P, Montico, M, Mooney, MD, Moore, AR, Moradi-Lakeh, M, Morawska, L, Mori, R, Mueller, U, Murthy, GVS, Murthy, S, Nachega, JB, Naheed, A, Naldi, L, Nand, D, Nangia, V, Nash, D, Neupane, S, Newton, JN, Ng, M, Ngalesoni, FN, Nguhiu, P, Nguyen, G, Le Nguyen, Q, Nisar, MI, Nomura, M, Norheim, OF, Norman, RE, Nyakarahuka, L, Obermeyer, CM, Ogbo, FA, Oh, I-H, Ojelabi, FA, Olivares, PR, Olusanya, BO, Olusanya, JO, Opio, JN, Oren, E, Ota, E, Oyekale, AS, Pa, M, Pain, A, Papantoniou, N, Park, E-K, Park, H-Y, Caicedo, AJP, Patten, SB, Paul, VK, Pereira, DM, Perico, N, Pesudovs, K, Petzold, M, Phillips, MR, Pillay, JD, Pishgar, F, Polinder, S, Pope, D, Pourmalek, F, Qorbani, M, Rafay, A, Rahimi, K, Rahimi-Movaghar, V, Rahman, M, Rahman, MHU, Rahman, SU, Rai, RK, Ram, U, Ranabhat, CL, Rangaswamy, T, Rao, PV, Refaat, AH, Remuzzi, G, Violante, FS, Kassebaum, NJ, Barber, RM, Bhutta, ZA, Dandona, L, Gething, PW, Hay, SI, Kinfu, Y, Larson, HJ, Liang, X, Lim, SS, Lopez, AD, Lozano, R, Mensah, GA, Mokdad, AH, Naghavi, M, Pinho, C, Salomon, JA, Steiner, C, Vos, T, Wang, H, Abajobir, AA, Abate, KH, Abbas, KM, Abd-Allah, F, Abdallat, MA, Abdulle, AM, Abera, SF, Aboyans, V, Abubakar, I, Abu-Rmeileh, NME, Achoki, T, Adebiyi, AO, Adedeji, IA, Adelekan, AL, Adou, AK, Afanvi, KA, Agarwal, A, Kiadaliri, AA, Ajala, ON, Akinyemiju, TF, Akseer, N, Al-Aly, Z, Alam, K, Alam, NKM, Alasfoor, D, Aldhahri, SF, Aldridge, RW, Alhabib, S, Ali, R, Alkerwi, A, Alla, F, Al-Raddadi, R, Alsharif, U, Martin, EA, Alvis-Guzman, N, Amare, AT, Amberbir, A, Amegah, AK, Ammar, W, Amrock, SM, Andersen, HH, Anderson, GM, Antoine, RM, Antonio, CAT, Aregay, AF, Arnlov, J, Arora, M, Arsenijevic, VSA, Al, A, Asayesh, H, Atique, S, Avokpaho, EFGA, Awasthi, A, Quintanilla, BPA, Azzopardi, P, Bacha, U, Badawi, A, Bahit, MC, Balakrishnan, K, Banerjee, A, Barac, A, Barker-Collo, SL, Barnighausen, T, Basu, S, Bayou, TA, Bayou, YT, Bazargan-Hejazi, S, Beardsley, J, Bedi, NW, Bekele, T, Bell, ML, Bennett, DA, Bensenor, IM, Berhane, A, Bernabe, E, Betsu, BD, Beyene, AS, Biadgilign, S, Bikbov, B, Bin Abdulhak, AA, Biroscak, BJ, Biryukov, S, Bisanzio, D, Bjertness, E, Blore, JD, Brainin, M, Brazinova, A, Breitborde, NJK, Brugha, TS, Butt, ZA, Campos-Nonato, IR, Campuzano, JC, Cardenas, R, Carrero, JJ, Carter, A, Casey, DC, Castaneda-Oquela, CA, Castro, RE, Catala-Lopez, F, Cavalleri, F, Chang, H-Y, Chang, J-C, Chavan, L, Chibueze, CE, Chisumpa, VH, Choi, J-YJ, Chowdhury, R, Christopher, DJ, Ciobanu, LG, Cirillo, M, Coates, MM, Coggeshall, M, Colistro, V, Colquhoun, SM, Cooper, C, Cooper, LT, Cortinovis, M, Dahiru, T, Damasceno, A, Danawi, H, Dandona, R, Das Neves, J, De Leo, D, Dellavalle, RP, Deribe, K, Deribew, A, Jarlais, DCD, Dharmaratne, SD, Dicker, DJ, Ding, EL, Dossou, E, Dubey, M, Ebel, BE, Ellingsen, CL, Elyazar, I, Endries, AY, Ermakov, SP, Eshrati, B, Esteghamati, A, Faraon, EJA, Farid, TA, Farinha, CSES, Faro, A, Farvid, MS, Farzadfar, F, Fereshtehnejad, S-M, Fernandes, JC, Fischer, F, Fitchett, JRA, Fleming, T, Gt, NF, Franca, EB, Franklin, RC, Fraser, MS, Friedman, J, Pullman, N, Furst, T, Futran, ND, Gambashidze, K, Gamkrelidze, A, Gebre, T, Gebrehiwot, TT, Gebremedhin, AT, Gebremedhin, M, Gebru, AA, Geleijnse, JM, Gibney, KB, Giref, AZ, Giroud, M, Gishu, MD, Glaser, E, Goenka, S, Gomez-Dantes, H, Gona, P, Goodridge, A, Gopalani, SV, Goto, A, Graetz, N, Gugnani, HC, Guo, Y, Gupta, R, Gupta, V, Hafezi-Nejad, N, Hailu, AD, Hailu, GB, Hamadeh, RR, Hamidi, S, Hancock, J, Handal, AJ, Hankey, GJ, Harb, HL, Harikrishnan, S, Harun, KM, Havmoeller, R, Hoek, HW, Horino, M, Horita, N, Hosgood, HD, Hoy, DG, Htet, AS, Hu, G, Huang, H, Huang, JJ, Huybrechts, I, Huynh, C, Iannarone, M, Iburg, KM, Idrisov, BT, Iyer, VJ, Jacobsen, KH, Jahanmehr, N, Jakovljevic, MB, Javanbakht, M, Jayatilleke, AU, Jee, SH, Jeemon, P, Jha, V, Jiang, G, Jiang, Y, Jibat, T, Jonas, JB, Kabir, Z, Kamal, R, Kan, H, Karch, A, Karletsos, D, Kasaeian, A, Kaul, A, Kawakami, N, Kayibanda, JF, Kazanjan, K, Kazi, DS, Keiyoro, PN, Kemmer, L, Kemp, AH, Kengne, AP, Keren, A, Kereselidze, M, Kesavachandran, CN, Khader, YS, Khan, AR, Khan, EA, Khang, Y-H, Khonelidze, I, Khosravi, A, Khubchandani, J, Kim, YJ, Kivipelto, M, Knibbs, LD, Kokubo, Y, Kosen, S, Koul, PA, Koyanagi, A, Krishnaswami, S, Defo, BK, Bicer, BK, Kudom, AA, Kulikoff, XR, Kulkarni, C, Kumar, GA, Kutz, MJ, Lal, DK, Lalloo, R, Lam, H, Lamadrid-Figueroa, H, Lan, Q, Larsson, A, Laryea, DO, Leigh, J, Leung, R, Li, Y, Lipshultz, SE, Liu, PY, Liu, S, Liu, Y, Lloyd, BK, Lotufo, PA, Lunevicius, R, Ma, S, El Razek, HMA, El Razek, MMA, Majdan, M, Majeed, A, Malekzadeh, R, Mapoma, CC, Marcenes, W, Margolis, DJ, Marquez, N, Masiye, F, Marzan, MB, Mason-Jones, AJ, Mazorodze, TT, Meaney, PA, Mehari, A, Mehndiratta, MM, Mena-Rodriguez, F, Mekonnen, AB, Melaku, YA, Memish, ZA, Mendoza, W, Meretoja, A, Meretoja, TJ, Mhimbira, FA, Miller, TR, Mills, EJ, Mirarefin, M, Misganaw, A, Ibrahim, NM, Mohammad, KA, Mohammadi, A, Mohammed, S, Mola, GLD, Monasta, L, Monis, JDLC, Hernandez, JCM, Montero, P, Montico, M, Mooney, MD, Moore, AR, Moradi-Lakeh, M, Morawska, L, Mori, R, Mueller, U, Murthy, GVS, Murthy, S, Nachega, JB, Naheed, A, Naldi, L, Nand, D, Nangia, V, Nash, D, Neupane, S, Newton, JN, Ng, M, Ngalesoni, FN, Nguhiu, P, Nguyen, G, Le Nguyen, Q, Nisar, MI, Nomura, M, Norheim, OF, Norman, RE, Nyakarahuka, L, Obermeyer, CM, Ogbo, FA, Oh, I-H, Ojelabi, FA, Olivares, PR, Olusanya, BO, Olusanya, JO, Opio, JN, Oren, E, Ota, E, Oyekale, AS, Pa, M, Pain, A, Papantoniou, N, Park, E-K, Park, H-Y, Caicedo, AJP, Patten, SB, Paul, VK, Pereira, DM, Perico, N, Pesudovs, K, Petzold, M, Phillips, MR, Pillay, JD, Pishgar, F, Polinder, S, Pope, D, Pourmalek, F, Qorbani, M, Rafay, A, Rahimi, K, Rahimi-Movaghar, V, Rahman, M, Rahman, MHU, Rahman, SU, Rai, RK, Ram, U, Ranabhat, CL, Rangaswamy, T, Rao, PV, Refaat, AH, Remuzzi, G, and Violante, FS

Abstract

BACKGROUND: In transitioning from the Millennium Development Goal to the Sustainable Development Goal era, it is imperative to comprehensively assess progress toward reducing maternal mortality to identify areas of success, remaining challenges, and frame policy discussions. We aimed to quantify maternal mortality throughout the world by underlying cause and age from 1990 to 2015. METHODS: We estimated maternal mortality at the global, regional, and national levels from 1990 to 2015 for ages 10-54 years by systematically compiling and processing all available data sources from 186 of 195 countries and territories, 11 of which were analysed at the subnational level. We quantified eight underlying causes of maternal death and four timing categories, improving estimation methods since GBD 2013 for adult all-cause mortality, HIV-related maternal mortality, and late maternal death. Secondary analyses then allowed systematic examination of drivers of trends, including the relation between maternal mortality and coverage of specific reproductive health-care services as well as assessment of observed versus expected maternal mortality as a function of Socio-demographic Index (SDI), a summary indicator derived from measures of income per capita, educational attainment, and fertility. FINDINGS: Only ten countries achieved MDG 5, but 122 of 195 countries have already met SDG 3.1. Geographical disparities widened between 1990 and 2015 and, in 2015, 24 countries still had a maternal mortality ratio greater than 400. The proportion of all maternal deaths occurring in the bottom two SDI quintiles, where haemorrhage is the dominant cause of maternal death, increased from roughly 68% in 1990 to more than 80% in 2015. The middle SDI quintile improved the most from 1990 to 2015, but also has the most complicated causal profile. Maternal mortality in the highest SDI quintile is mostly due to other direct maternal disorders, indirect maternal disorders, and abortion, ectopic pregnancy

Published
2016

32. Global, regional, and national levels of maternal mortality, 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015

Author

Kassebaum, N., Barber, R., Bhutta, Z., Dandona, L., Gething, P., Hay, S., Kinfu, Y., Larson, H., Liang, X., Lim, S., Lopez, A., Lozano, R., Mensah, G., Mokdad, A., Naghavi, M., Pinho, C., Salomon, J., Steiner, C., Vos, T., Wang, H., Abajobir, A., Abate, K., Abbas, K., Abd-Allah, F., Abdallat, M., Abdulle, A., Abera, S., Aboyans, V., Abubakar, I., Abu-Rmeileh, N., Achoki, T., Adebiyi, A., Adedeji, I., Adelekan, A., Adou, A., Afanvi, K., Agarwal, A., Kiadaliri, A., Ajala, O., Akinyemiju, T., Akseer, N., Al-Aly, Z., Alam, K., Alam, N., Alasfoor, D., Aldhahri, S., Aldridge, R., Alhabib, S., Ali, R., Alkerwi, A., Alla, F., Al-Raddadi, R., Alsharif, U., Martin, E., Alvis-Guzman, N., Amare, A., Amberbir, A., Amegah, A., Ammar, W., Amrock, S., Andersen, H., Anderson, G., Antoine, R., Antonio, C., Aregay, A., Arnlov, J., Arora, M., Arsenijevic, V., Al, A., Asayesh, H., Atique, S., Avokpaho, E., Awasthi, A., Quintanilla, B., Azzopardi, P., Bacha, U., Badawi, A., Bahit, M., Balakrishnan, K., Banerjee, A., Barac, A., Barker-Collo, S., Barnighausen, T., Basu, S., Bayou, T., Bayou, Y., Bazargan-Hejazi, S., Beardsley, J., Bedi, N., Bekele, T., Bell, M., Bennett, D., Bensenor, I., Berhane, A., Bernabe, E., Betsu, B., Beyene, A., Biadgilign, S., Bikbov, B., Bin Abdulhak, A., Biroscak, B., Biryukov, S., Bisanzio, D., Bjertness, E., Blore, J., Brainin, M., Brazinova, A., Breitborde, N., Brugha, T., Butt, Z., Campos-Nonato, I., Campuzano, J., Cardenas, R., Carrero, J., Carter, A., Casey, D., Castaneda-Oquela, C., Castro, R., Catala-Lopez, F., Cavalleri, F., Chang, H., Chang, J., Chavan, L., Chibueze, C., Chisumpa, V., Choi, J., Chowdhury, R., Christopher, D., Ciobanu, L., Cirillo, M., Coates, M., Coggeshall, M., Colistro, V., Colquhoun, S., Cooper, C., Cooper, L., Cortinovis, M., Dahiru, T., Damasceno, A., Danawi, H., Dandona, R., Das Neves, J., De Leo, D., Dellavalle, R., Deribe, K., Deribew, A., Jarlais, D., Dharmaratne, S., Dicker, D., Ding, E., Dossou, E., Dubey, M., Ebel, B., Ellingsen, C., Elyazar, I., Endries, A., Ermakov, S., Eshrati, B., Esteghamati, A., Faraon, E., Farid, T., Farinha, C., Faro, A., Farvid, M., Farzadfar, F., Fereshtehnejad, S., Fernandes, J., Fischer, F., Fitchett, J., Fleming, T., Gt, N., Franca, E., Franklin, R., Fraser, M., Friedman, J., Pullman, N., Furst, T., Futran, N., Gambashidze, K., Gamkrelidze, A., Gebre, T., Gebrehiwot, T., Gebremedhin, A., Gebremedhin, M., Gebru, A., Geleijnse, J., Gibney, K., Giref, A., Giroud, M., Gishu, M., Glaser, E., Goenka, S., Gomez-Dantes, H., Gona, P., Goodridge, A., Gopalani, S., Goto, A., Graetz, N., Gugnani, H., Guo, Y., Gupta, R., Gupta, V., Hafezi-Nejad, N., Hailu, A., Hailu, G., Hamadeh, R., Hamidi, S., Hancock, J., Handal, A., Hankey, G., Harb, H., Harikrishnan, S., Harun, K., Havmoeller, R., Hoek, H., Horino, M., Horita, N., Hosgood, H., Hoy, D., Htet, A., Hu, G., Huang, H., Huang, J., Huybrechts, I., Huynh, C., Iannarone, M., Iburg, K., Idrisov, B., Iyer, V., Jacobsen, K., Jahanmehr, N., Jakovljevic, M., Javanbakht, M., Jayatilleke, A., Jee, S., Jeemon, P., Jha, V., Jiang, G., Jiang, Y., Jibat, T., Jonas, J., Kabir, Z., Kamal, R., Kan, H., Karch, A., Karletsos, D., Kasaeian, A., Kaul, A., Kawakami, N., Kayibanda, J., Kazanjan, K., Kazi, D., Keiyoro, P., Kemmer, L., Kemp, A., Kengne, A., Keren, A., Kereselidze, M., Kesavachandran, C., Khader, Y., Khan, A., Khan, E., Khang, Y., Khonelidze, I., Khosravi, A., Khubchandani, J., Kim, Y., Kivipelto, M., Knibbs, L., Kokubo, Y., Kosen, S., Koul, P., Koyanagi, A., Krishnaswami, S., Defo, B., Bicer, B., Kudom, A., Kulikoff, X., Kulkarni, C., Kumar, G., Kutz, M., Lal, D., Lalloo, R., Lam, H., Lamadrid-Figueroa, H., Lan, Q., Larsson, A., Laryea, D., Leigh, J., Leung, R., Li, Y., Lipshultz, S., Liu, P., Liu, S., Liu, Y., Lloyd, B., Lotufo, P., Lunevicius, R., Ma, S., El Razek, H., El Razek, M., Majdan, M., Majeed, A., Malekzadeh, R., Mapoma, C., Marcenes, W., Margolis, D., Marquez, N., Masiye, F., Marzan, M., Mason-Jones, A., Mazorodze, T., Meaney, P., Mehari, A., Mehndiratta, M., Mena-Rodriguez, F., Mekonnen, A., Melaku, Y., Memish, Z., Mendoza, W., Meretoja, A., Meretoja, T., Mhimbira, F., Miller, Ted, Mills, E., Mirarefin, M., Misganaw, A., Ibrahim, N., Mohammad, K., Mohammadi, A., Mohammed, S., Mola, G., Monasta, L., Monis, J., Hernandez, J., Montero, P., Montico, M., Mooney, M., Moore, A., Moradi-Lakeh, M., Morawska, L., Mori, R., Mueller, U., Murthy, G., Murthy, S., Nachega, J., Naheed, A., Naldi, L., Nand, D., Nangia, V., Nash, D., Neupane, S., Newton, J., Ng, M., Ngalesoni, F., Nguhiu, P., Nguyen, G., Le Nguyen, Q., Nisar, M., Nomura, M., Norheim, O., Norman, R., Nyakarahuka, L., Obermeyer, C., Ogbo, F., Oh, I., Ojelabi, F., Olivares, P., Olusanya, B., Olusanya, J., Opio, J., Oren, E., Ota, E., Oyekale, A., Pa, M., Pain, A., Papantoniou, N., Park, E., Park, H., Caicedo, A., Patten, S., Paul, V., Pereira, D., Perico, N., Pesudovs, K., Petzold, M., Phillips, M., Pillay, J., Pishgar, F., Polinder, S., Pope, D., Pourmalek, F., Qorbani, M., Rafay, A., Rahimi, K., Rahimi-Movaghar, V., Rahman, M., Rahman, S., Rai, R., Ram, U., Ranabhat, C., Rangaswamy, T., Rao, P., Refaat, A., Remuzzi, G., Kassebaum, N., Barber, R., Bhutta, Z., Dandona, L., Gething, P., Hay, S., Kinfu, Y., Larson, H., Liang, X., Lim, S., Lopez, A., Lozano, R., Mensah, G., Mokdad, A., Naghavi, M., Pinho, C., Salomon, J., Steiner, C., Vos, T., Wang, H., Abajobir, A., Abate, K., Abbas, K., Abd-Allah, F., Abdallat, M., Abdulle, A., Abera, S., Aboyans, V., Abubakar, I., Abu-Rmeileh, N., Achoki, T., Adebiyi, A., Adedeji, I., Adelekan, A., Adou, A., Afanvi, K., Agarwal, A., Kiadaliri, A., Ajala, O., Akinyemiju, T., Akseer, N., Al-Aly, Z., Alam, K., Alam, N., Alasfoor, D., Aldhahri, S., Aldridge, R., Alhabib, S., Ali, R., Alkerwi, A., Alla, F., Al-Raddadi, R., Alsharif, U., Martin, E., Alvis-Guzman, N., Amare, A., Amberbir, A., Amegah, A., Ammar, W., Amrock, S., Andersen, H., Anderson, G., Antoine, R., Antonio, C., Aregay, A., Arnlov, J., Arora, M., Arsenijevic, V., Al, A., Asayesh, H., Atique, S., Avokpaho, E., Awasthi, A., Quintanilla, B., Azzopardi, P., Bacha, U., Badawi, A., Bahit, M., Balakrishnan, K., Banerjee, A., Barac, A., Barker-Collo, S., Barnighausen, T., Basu, S., Bayou, T., Bayou, Y., Bazargan-Hejazi, S., Beardsley, J., Bedi, N., Bekele, T., Bell, M., Bennett, D., Bensenor, I., Berhane, A., Bernabe, E., Betsu, B., Beyene, A., Biadgilign, S., Bikbov, B., Bin Abdulhak, A., Biroscak, B., Biryukov, S., Bisanzio, D., Bjertness, E., Blore, J., Brainin, M., Brazinova, A., Breitborde, N., Brugha, T., Butt, Z., Campos-Nonato, I., Campuzano, J., Cardenas, R., Carrero, J., Carter, A., Casey, D., Castaneda-Oquela, C., Castro, R., Catala-Lopez, F., Cavalleri, F., Chang, H., Chang, J., Chavan, L., Chibueze, C., Chisumpa, V., Choi, J., Chowdhury, R., Christopher, D., Ciobanu, L., Cirillo, M., Coates, M., Coggeshall, M., Colistro, V., Colquhoun, S., Cooper, C., Cooper, L., Cortinovis, M., Dahiru, T., Damasceno, A., Danawi, H., Dandona, R., Das Neves, J., De Leo, D., Dellavalle, R., Deribe, K., Deribew, A., Jarlais, D., Dharmaratne, S., Dicker, D., Ding, E., Dossou, E., Dubey, M., Ebel, B., Ellingsen, C., Elyazar, I., Endries, A., Ermakov, S., Eshrati, B., Esteghamati, A., Faraon, E., Farid, T., Farinha, C., Faro, A., Farvid, M., Farzadfar, F., Fereshtehnejad, S., Fernandes, J., Fischer, F., Fitchett, J., Fleming, T., Gt, N., Franca, E., Franklin, R., Fraser, M., Friedman, J., Pullman, N., Furst, T., Futran, N., Gambashidze, K., Gamkrelidze, A., Gebre, T., Gebrehiwot, T., Gebremedhin, A., Gebremedhin, M., Gebru, A., Geleijnse, J., Gibney, K., Giref, A., Giroud, M., Gishu, M., Glaser, E., Goenka, S., Gomez-Dantes, H., Gona, P., Goodridge, A., Gopalani, S., Goto, A., Graetz, N., Gugnani, H., Guo, Y., Gupta, R., Gupta, V., Hafezi-Nejad, N., Hailu, A., Hailu, G., Hamadeh, R., Hamidi, S., Hancock, J., Handal, A., Hankey, G., Harb, H., Harikrishnan, S., Harun, K., Havmoeller, R., Hoek, H., Horino, M., Horita, N., Hosgood, H., Hoy, D., Htet, A., Hu, G., Huang, H., Huang, J., Huybrechts, I., Huynh, C., Iannarone, M., Iburg, K., Idrisov, B., Iyer, V., Jacobsen, K., Jahanmehr, N., Jakovljevic, M., Javanbakht, M., Jayatilleke, A., Jee, S., Jeemon, P., Jha, V., Jiang, G., Jiang, Y., Jibat, T., Jonas, J., Kabir, Z., Kamal, R., Kan, H., Karch, A., Karletsos, D., Kasaeian, A., Kaul, A., Kawakami, N., Kayibanda, J., Kazanjan, K., Kazi, D., Keiyoro, P., Kemmer, L., Kemp, A., Kengne, A., Keren, A., Kereselidze, M., Kesavachandran, C., Khader, Y., Khan, A., Khan, E., Khang, Y., Khonelidze, I., Khosravi, A., Khubchandani, J., Kim, Y., Kivipelto, M., Knibbs, L., Kokubo, Y., Kosen, S., Koul, P., Koyanagi, A., Krishnaswami, S., Defo, B., Bicer, B., Kudom, A., Kulikoff, X., Kulkarni, C., Kumar, G., Kutz, M., Lal, D., Lalloo, R., Lam, H., Lamadrid-Figueroa, H., Lan, Q., Larsson, A., Laryea, D., Leigh, J., Leung, R., Li, Y., Lipshultz, S., Liu, P., Liu, S., Liu, Y., Lloyd, B., Lotufo, P., Lunevicius, R., Ma, S., El Razek, H., El Razek, M., Majdan, M., Majeed, A., Malekzadeh, R., Mapoma, C., Marcenes, W., Margolis, D., Marquez, N., Masiye, F., Marzan, M., Mason-Jones, A., Mazorodze, T., Meaney, P., Mehari, A., Mehndiratta, M., Mena-Rodriguez, F., Mekonnen, A., Melaku, Y., Memish, Z., Mendoza, W., Meretoja, A., Meretoja, T., Mhimbira, F., Miller, Ted, Mills, E., Mirarefin, M., Misganaw, A., Ibrahim, N., Mohammad, K., Mohammadi, A., Mohammed, S., Mola, G., Monasta, L., Monis, J., Hernandez, J., Montero, P., Montico, M., Mooney, M., Moore, A., Moradi-Lakeh, M., Morawska, L., Mori, R., Mueller, U., Murthy, G., Murthy, S., Nachega, J., Naheed, A., Naldi, L., Nand, D., Nangia, V., Nash, D., Neupane, S., Newton, J., Ng, M., Ngalesoni, F., Nguhiu, P., Nguyen, G., Le Nguyen, Q., Nisar, M., Nomura, M., Norheim, O., Norman, R., Nyakarahuka, L., Obermeyer, C., Ogbo, F., Oh, I., Ojelabi, F., Olivares, P., Olusanya, B., Olusanya, J., Opio, J., Oren, E., Ota, E., Oyekale, A., Pa, M., Pain, A., Papantoniou, N., Park, E., Park, H., Caicedo, A., Patten, S., Paul, V., Pereira, D., Perico, N., Pesudovs, K., Petzold, M., Phillips, M., Pillay, J., Pishgar, F., Polinder, S., Pope, D., Pourmalek, F., Qorbani, M., Rafay, A., Rahimi, K., Rahimi-Movaghar, V., Rahman, M., Rahman, S., Rai, R., Ram, U., Ranabhat, C., Rangaswamy, T., Rao, P., Refaat, A., and Remuzzi, G.

Published
2016

33. Global, regional, and national life expectancy, all-cause mortality, and cause-specific mortality for 249 causes of death, 1980-2015: a systematic analysis for the Global Burden of Disease Study 2015

Author

Wang, H., Naghavi, M., Allen, C., Barber, R., Bhutta, Z., Carter, A., Casey, D., Charlson, F., Chen, A., Coates, M., Coggeshall, M., Dandona, L., Dicker, D., Erskine, H., Ferrari, A., Fitzmaurice, C., Foreman, K., Forouzanfar, M., Fraser, M., Pullman, N., Gething, P., Goldberg, E., Graetz, N., Haagsma, J., Hay, S., Huynh, C., Johnson, C., Kassebaum, N., Kinfu, Y., Kulikoff, X., Kutz, M., Kyu, H., Larson, H., Leung, J., Liang, X., Lim, S., Lind, M., Lozano, R., Marquez, N., Mensah, G., Mikesell, J., Mokdad, A., Mooney, M., Nguyen, G., Nsoesie, E., Pigott, D., Pinho, C., Roth, G., Salomon, J., Sandar, L., Silpakit, N., Sligar, A., Sorensen, R., Stanaway, J., Steiner, C., Teeple, S., Thomas, B., Troeger, C., VanderZanden, A., Vollset, S., Wanga, V., Whiteford, H., Wolock, T., Zoeckler, L., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abera, S., Abreu, D., Abu-Raddad, L., Abyu, G., Achoki, T., Adelekan, A., Ademi, Z., Adou, A., Adsuar, J., Afanvi, K., Afshin, A., Agardh, E., Agarwal, A., Agrawal, A., Kiadaliri, A., Ajala, O., Akanda, A., Akinyemi, R., Akinyemiju, T., Akseer, N., Al Lami, F., Alabed, S., Al-Aly, Z., Alam, K., Alam, N., Alasfoor, D., Aldhahri, S., Aldridge, R., Alegretti, M., Aleman, A., Alemu, Z., Alexander, L., Alhabib, S., Ali, R., Alkerwi, A., Alla, F., Allebeck, P., Al-Raddadi, R., Alsharif, U., Altirkawi, K., Martin, E., Alvis-Guzman, N., Amare, A., Amegah, A., Ameh, E., Amini, H., Ammar, W., Amrock, S., Andersen, H., Anderson, B., Anderson, G., Antonio, C., Aregay, A., Arnlov, J., Arsenijevic, V., Al, A., Asayesh, H., Asghar, R., Atique, S., Arthur Avokpaho, E., Awasthi, A., Azzopardi, P., Bacha, U., Badawi, A., Bahit, M., Balakrishnan, K., Banerjee, A., Barac, A., Barker-Collo, S., Barnighausen, T., Barregard, L., Barrero, L., Basu, A., Basu, S., Bayou, Y., Bazargan-Hejazi, S., Beardsley, J., Bedi, N., Beghi, E., Belay, H., Bell, B., Bell, M., Bello, A., Bennett, D., Bensenor, I., Berhane, A., Bernabe, E., Betsu, B., Beyene, A., Bhala, N., Bhalla, A., Biadgilign, S., Bikbov, B., Bin Abdulhak, A., Biroscak, B., Biryukov, S., Bjertness, E., Blore, J., Blosser, C., Bohensky, M., Borschmann, R., Bose, D., Bourne, R., Brainin, M., Brayne, C., Brazinova, A., Breitborde, N., Brenner, H., Brewer, J., Brown, A., Brown, J., Brugha, T., Buckle, G., Butt, Z., Calabria, B., Campos-Novato, I., Campuzano, J., Carapetis, J., Cardenas, R., Carpenter, D., Carrero, J., Castaneda-Oquela, C., Rivas, J., Catala-Lopez, F., Cavalleri, F., Cercy, K., Cerda, J., Chen, W., Chew, A., Chiang, P., Chibalabala, M., Chibueze, C., Chimed-Ochir, O., Chisumpa, V., Choi, J., Chowdhury, R., Christensen, H., Christopher, D., Ciobanu, L., Cirillo, M., Cohen, A., Colistro, V., Colomar, M., Colquhoun, S., Cooper, C., Cooper, L., Cortinovis, M., Cowie, B., Crump, J., Damsere-Derry, J., Danawi, H., Dandona, R., Daoud, F., Darby, S., Dargan, P., das Neves, J., Davey, G., Davis, A., Davitoiu, D., de Castro, E., de Jager, P., De Leo, D., Degenhardt, L., Dellavalle, R., Deribe, K., Deribew, A., Dharmaratne, S., Dhillon, P., Diaz-Torne, C., Ding, E., dos Santos, K., Dossou, E., Driscoll, T., Duan, L., Dubey, M., Bartholow, B., Ellenbogen, R., Lycke, C., Elyazar, I., Endries, A., Ermakov, S., Eshrati, B., Esteghamati, A., Estep, K., Faghmous, I., Fahimi, S., Jose, E., Farid, T., Sa Farinha, C., Faro, A., Farvid, M., Farzadfar, F., Feigin, V., Fereshtehnejad, S., Fernandes, J., Fischer, F., Fitchett, J., Flaxman, A., Foigt, N., Fowkes, F., Franca, E., Franklin, R., Friedman, J., Frostad, J., Hirst, T., Futran, N., Gall, S., Gambashidze, K., Gamkrelidze, A., Ganguly, P., Gankpe, F., Gebre, T., Gebrehiwot, T., Gebremedhin, A., Gebru, A., Geleijnse, J., Gessner, B., Ghoshal, A., Gibney, K., Gillum, R., Gilmour, S., Giref, A., Giroud, M., Gishu, M., Giussani, G., Glaser, E., Godwin, W., Gomez-Dantes, H., Gona, P., Goodridge, A., Gopalani, S., Gosselin, R., Gotay, C., Goto, A., Gouda, H., Greaves, F., Gugnani, H., Gupta, R., Gupta, V., Gutierrez, R., Hafezi-Nejad, N., Haile, D., Hailu, A., Hailu, G., Halasa, Y., Hamadeh, R., Hamidi, S., Hancock, J., Handal, A., Hankey, G., Hao, Y., Harb, H., Harikrishnan, S., Haro, J., Havmoeller, R., Heckbert, S., Heredia-Pi, I., Heydarpour, P., Hilderink, H., Hoek, H., Hogg, R., Horino, M., Horita, N., Hosgood, H., Hotez, P., Hoy, D., Hsairi, M., Htet, A., Than Htike, M., Hu, G., Huang, C., Huang, H., Huiart, L., Husseini, A., Huybrechts, I., Huynh, G., Iburg, K., Innos, K., Inoue, M., Iyer, V., Jacobs, T., Jacobsen, K., Jahanmehr, N., Jakovljevic, M., James, P., Javanbakht, M., Jayaraman, S., Jayatilleke, A., Jeemon, P., Jensen, P., Jha, V., Jiang, G., Jiang, Y., Jibat, T., Jimenez-Corona, A., Jonas, J., Joshi, T., Kabir, Z., Karnak, R., Kan, H., Kant, S., Karch, A., Karema, C., Karimkhani, C., Karletsos, D., Karthikeyan, G., Kasaeian, A., Katibeh, M., Kaul, A., Kawakami, N., Kayibanda, J., Keiyoro, P., Kemmer, L., Kemp, A., Kengne, A., Keren, A., Kereselidze, M., Kesavachandran, C., Khader, Y., Khalil, I., Khan, A., Khan, E., Khang, Y., Khera, S., Muthafer Khoja, T., Kieling, C., Kim, D., Kim, Y., Kissela, B., Kissoon, N., Knibbs, L., Knudsen, A., Kokubo, Y., Kolte, D., Kopec, J., Kosen, S., Koul, P., Koyanagi, A., Krog, N., Defo, B., Bicer, B., Kudom, A., Kuipers, E., Kulkarni, V., Kumar, G., Kwan, G., Lal, A., Lal, D., Lalloo, R., Lam, H., Lam, J., Langan, S., Lansingh, V., Larsson, A., Laryea, D., Latif, A., Lawrynowicz, A., Leigh, J., Levi, M., Li, Y., Lindsay, M., Lipshultz, S., Liu, P., Liu, S., Liu, Y., Lo, L., Logroscino, G., Lotufo, P., Lucas, R., Lunevicius, R., Lyons, R., Ma, S., Pedro Machado, V., Mackay, M., MacLachlan, J., Abd El Razek, H., Abd El Razek, M., Majdan, M., Majeed, A., Malekzadeh, R., Ayele Manamo, W., Mandisarisa, J., Mangalam, S., Mapoma, C., Marcenes, W., Margolis, D., Martin, G., Martinez-Raga, J., Marzan, M., Masiye, F., Mason-Jones, A., Massano, J., Matzopoulos, R., Mayosi, B., McGarvey, S., McGrath, J., Mckee, M., McMahon, B., Meaney, P., Mehari, A., Mehndiratta, M., Mena-Rodriguez, F., Mekonnen, A., Melaku, Y., Memiah, P., Memish, Z., Mendoza, W., Meretoja, A., Meretoja, T., Mhimbira, F., Micha, R., Miller, Ted, Mirarefin, M., Misganaw, A., Mock, C., Abdulmuhsin Mohammad, K., Mohammadi, A., Mohammed, S., Mohan, V., Mola, G., Monasta, L., Montanez Hernandez, J., Montero, P., Montico, M., Montine, T., Moradi-Lakeh, M., Morawska, L., Morgan, K., Mori, R., Mozaffarian, D., Mueller, U., Satyanarayana Murthy, G., Murthy, S., Musa, K., Nachega, J., Nagel, G., Naidoo, K., Naik, N., Naldi, L., Nangia, V., Nash, D., Nejjari, C., Neupane, S., Newton, C., Newton, J., Ng, M., Ngalesoni, F., Ngirabega, J., Quyen, L., Nisar, M., Nkamedjie Pete, P., Nomura, M., Norheim, O., Norman, P., Norrving, B., Nyakarahuka, L., Ogbo, F., Ohkubo, T., Ojelabi, F., Olivares, P., Olusanya, B., Olusanya, J., Opio, J., Oren, E., Ortiz, A., Osman, M., Ota, E., Ozdemir, R., Pa, M., Pandian, J., Pant, P., Papachristou, C., Park, E., Park, J., Parry, C., Parsaeian, M., Caicedo, A., Patten, S., Patton, G., Paul, V., Pearce, N., Pedro, J., Stokic, L., Pereira, D., Perico, N., Pesudovs, K., Petzold, M., Phillips, M., Piel, F., Pillay, J., Plass, D., Platts-Mills, J., Polinder, S., Pope, C., Popova, S., Poulton, R., Pourmalek, F., Prabhakaran, D., Qorbani, M., Quame-Amaglo, J., Quistberg, D., Rafay, A., Rahimi, K., Rahimi-Movaghar, V., Rahman, M., Rahman, S., Rai, R., Rajavi, Z., Rajsic, S., Raju, M., Rakovac, I., Rana, S., Ranabhat, C., Rangaswamy, T., Rao, P., Rao, S., Refaat, A., Rehm, J., Reitsma, M., Remuzzi, G., Resnikofff, S., Ribeiro, A., Ricci, S., Blancas, M., Roberts, B., Roca, A., Rojas-Rueda, D., Ronfani, L., Roshandel, G., Rothenbacher, D., Roy, A., Roy, N., Ruhago, G., Sagar, R., Saha, S., Sahathevan, R., Saleh, M., Sanabria, J., Sanchez-Nino, M., Sanchez-Riera, L., Santos, I., Sarmiento-Suarez, R., Sartorius, B., Satpathy, M., Savic, M., Sawhney, M., Schaub, M., Schmidt, M., Schneider, I., Schottker, B., Schutte, A., Schwebel, D., Seedat, S., Sepanlou, S., Servan-Mori, E., Shackelford, K., Shaddick, G., Shaheen, A., Shahraz, S., Shaikh, M., Shakh-Nazarova, M., Sharma, R., She, J., Sheikhbahaei, S., Shen, J., Shen, Z., Shepard, D., Sheth, K., Shetty, B., Shi, P., Shibuya, K., Shin, M., Shiri, R., Shiue, I., Shrime, M., Sigfusdottir, I., Silberberg, D., Silva, D., Silveira, D., Silverberg, J., Simard, E., Singh, A., Singh, G., Singh, J., Singh, O., Singh, P., Singh, V., Soneji, S., Soreide, K., Soriano, J., Sposato, L., Sreeramareddy, C., Stathopoulou, V., Stein, D., Stein, M., Stranges, S., Stroumpoulis, K., Sunguya, B., Sur, P., Swaminathan, S., Sykes, B., Szoeke, C., Tabares-Seisdedos, R., Tabb, K., Takahashi, K., Takala, J., Talongwa, R., Tandon, N., Tavakkoli, M., Taye, B., Taylor, H., Ao, B., Tedla, B., Tefera, W., Ten Have, M., Terkawi, A., Tesfay, F., Tessema, G., Thomson, A., Thorne-Lyman, A., Thrift, A., Thurston, G., Tillmann, T., Tirschwell, D., Tonelli, M., Topor-Madry, R., Topouzis, F., Nx, J., Traebert, J., Tran, B., Truelsen, T., Trujillo, U., Tura, A., Tuzcu, E., Uchendu, U., Ukwaja, K., Undurraga, E., Uthman, O., Van Dingenen, R., Van Donkelaar, A., Vasankari, T., Vasconcelos, A., Venketasubramanian, N., Vidavalur, R., Vijayakumar, L., Villalpando, S., Violante, F., Vlassov, V., Wagner, J., Wagner, G., Wallin, M., Wang, L., Watkins, D., Weichenthal, S., Weiderpass, E., Weintraub, R., Werdecker, A., Westerman, R., White, R., Wijeratne, T., Wilkinson, J., Williams, H., Wiysonge, C., Woldeyohannes, S., Wolfe, C., Won, S., Wong, J., Woolf, A., Xavier, D., Xiao, Q., Xu, G., Yakob, B., Yalew, A., Yan, L., Yano, Y., Yaseri, M., Ye, P., Yebyo, H., Yip, P., Yirsaw, B., Yonemoto, N., Yonga, G., Younis, M., Yu, S., Zaidi, Z., Zaki, M., Zannad, F., Zavala, D., Zeeb, H., Zeleke, B., Zhang, H., Zodpey, S., Zonies, D., Zuhlke, L., Vos, T., Lopez, A., Murray, C., Wang, H., Naghavi, M., Allen, C., Barber, R., Bhutta, Z., Carter, A., Casey, D., Charlson, F., Chen, A., Coates, M., Coggeshall, M., Dandona, L., Dicker, D., Erskine, H., Ferrari, A., Fitzmaurice, C., Foreman, K., Forouzanfar, M., Fraser, M., Pullman, N., Gething, P., Goldberg, E., Graetz, N., Haagsma, J., Hay, S., Huynh, C., Johnson, C., Kassebaum, N., Kinfu, Y., Kulikoff, X., Kutz, M., Kyu, H., Larson, H., Leung, J., Liang, X., Lim, S., Lind, M., Lozano, R., Marquez, N., Mensah, G., Mikesell, J., Mokdad, A., Mooney, M., Nguyen, G., Nsoesie, E., Pigott, D., Pinho, C., Roth, G., Salomon, J., Sandar, L., Silpakit, N., Sligar, A., Sorensen, R., Stanaway, J., Steiner, C., Teeple, S., Thomas, B., Troeger, C., VanderZanden, A., Vollset, S., Wanga, V., Whiteford, H., Wolock, T., Zoeckler, L., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abera, S., Abreu, D., Abu-Raddad, L., Abyu, G., Achoki, T., Adelekan, A., Ademi, Z., Adou, A., Adsuar, J., Afanvi, K., Afshin, A., Agardh, E., Agarwal, A., Agrawal, A., Kiadaliri, A., Ajala, O., Akanda, A., Akinyemi, R., Akinyemiju, T., Akseer, N., Al Lami, F., Alabed, S., Al-Aly, Z., Alam, K., Alam, N., Alasfoor, D., Aldhahri, S., Aldridge, R., Alegretti, M., Aleman, A., Alemu, Z., Alexander, L., Alhabib, S., Ali, R., Alkerwi, A., Alla, F., Allebeck, P., Al-Raddadi, R., Alsharif, U., Altirkawi, K., Martin, E., Alvis-Guzman, N., Amare, A., Amegah, A., Ameh, E., Amini, H., Ammar, W., Amrock, S., Andersen, H., Anderson, B., Anderson, G., Antonio, C., Aregay, A., Arnlov, J., Arsenijevic, V., Al, A., Asayesh, H., Asghar, R., Atique, S., Arthur Avokpaho, E., Awasthi, A., Azzopardi, P., Bacha, U., Badawi, A., Bahit, M., Balakrishnan, K., Banerjee, A., Barac, A., Barker-Collo, S., Barnighausen, T., Barregard, L., Barrero, L., Basu, A., Basu, S., Bayou, Y., Bazargan-Hejazi, S., Beardsley, J., Bedi, N., Beghi, E., Belay, H., Bell, B., Bell, M., Bello, A., Bennett, D., Bensenor, I., Berhane, A., Bernabe, E., Betsu, B., Beyene, A., Bhala, N., Bhalla, A., Biadgilign, S., Bikbov, B., Bin Abdulhak, A., Biroscak, B., Biryukov, S., Bjertness, E., Blore, J., Blosser, C., Bohensky, M., Borschmann, R., Bose, D., Bourne, R., Brainin, M., Brayne, C., Brazinova, A., Breitborde, N., Brenner, H., Brewer, J., Brown, A., Brown, J., Brugha, T., Buckle, G., Butt, Z., Calabria, B., Campos-Novato, I., Campuzano, J., Carapetis, J., Cardenas, R., Carpenter, D., Carrero, J., Castaneda-Oquela, C., Rivas, J., Catala-Lopez, F., Cavalleri, F., Cercy, K., Cerda, J., Chen, W., Chew, A., Chiang, P., Chibalabala, M., Chibueze, C., Chimed-Ochir, O., Chisumpa, V., Choi, J., Chowdhury, R., Christensen, H., Christopher, D., Ciobanu, L., Cirillo, M., Cohen, A., Colistro, V., Colomar, M., Colquhoun, S., Cooper, C., Cooper, L., Cortinovis, M., Cowie, B., Crump, J., Damsere-Derry, J., Danawi, H., Dandona, R., Daoud, F., Darby, S., Dargan, P., das Neves, J., Davey, G., Davis, A., Davitoiu, D., de Castro, E., de Jager, P., De Leo, D., Degenhardt, L., Dellavalle, R., Deribe, K., Deribew, A., Dharmaratne, S., Dhillon, P., Diaz-Torne, C., Ding, E., dos Santos, K., Dossou, E., Driscoll, T., Duan, L., Dubey, M., Bartholow, B., Ellenbogen, R., Lycke, C., Elyazar, I., Endries, A., Ermakov, S., Eshrati, B., Esteghamati, A., Estep, K., Faghmous, I., Fahimi, S., Jose, E., Farid, T., Sa Farinha, C., Faro, A., Farvid, M., Farzadfar, F., Feigin, V., Fereshtehnejad, S., Fernandes, J., Fischer, F., Fitchett, J., Flaxman, A., Foigt, N., Fowkes, F., Franca, E., Franklin, R., Friedman, J., Frostad, J., Hirst, T., Futran, N., Gall, S., Gambashidze, K., Gamkrelidze, A., Ganguly, P., Gankpe, F., Gebre, T., Gebrehiwot, T., Gebremedhin, A., Gebru, A., Geleijnse, J., Gessner, B., Ghoshal, A., Gibney, K., Gillum, R., Gilmour, S., Giref, A., Giroud, M., Gishu, M., Giussani, G., Glaser, E., Godwin, W., Gomez-Dantes, H., Gona, P., Goodridge, A., Gopalani, S., Gosselin, R., Gotay, C., Goto, A., Gouda, H., Greaves, F., Gugnani, H., Gupta, R., Gupta, V., Gutierrez, R., Hafezi-Nejad, N., Haile, D., Hailu, A., Hailu, G., Halasa, Y., Hamadeh, R., Hamidi, S., Hancock, J., Handal, A., Hankey, G., Hao, Y., Harb, H., Harikrishnan, S., Haro, J., Havmoeller, R., Heckbert, S., Heredia-Pi, I., Heydarpour, P., Hilderink, H., Hoek, H., Hogg, R., Horino, M., Horita, N., Hosgood, H., Hotez, P., Hoy, D., Hsairi, M., Htet, A., Than Htike, M., Hu, G., Huang, C., Huang, H., Huiart, L., Husseini, A., Huybrechts, I., Huynh, G., Iburg, K., Innos, K., Inoue, M., Iyer, V., Jacobs, T., Jacobsen, K., Jahanmehr, N., Jakovljevic, M., James, P., Javanbakht, M., Jayaraman, S., Jayatilleke, A., Jeemon, P., Jensen, P., Jha, V., Jiang, G., Jiang, Y., Jibat, T., Jimenez-Corona, A., Jonas, J., Joshi, T., Kabir, Z., Karnak, R., Kan, H., Kant, S., Karch, A., Karema, C., Karimkhani, C., Karletsos, D., Karthikeyan, G., Kasaeian, A., Katibeh, M., Kaul, A., Kawakami, N., Kayibanda, J., Keiyoro, P., Kemmer, L., Kemp, A., Kengne, A., Keren, A., Kereselidze, M., Kesavachandran, C., Khader, Y., Khalil, I., Khan, A., Khan, E., Khang, Y., Khera, S., Muthafer Khoja, T., Kieling, C., Kim, D., Kim, Y., Kissela, B., Kissoon, N., Knibbs, L., Knudsen, A., Kokubo, Y., Kolte, D., Kopec, J., Kosen, S., Koul, P., Koyanagi, A., Krog, N., Defo, B., Bicer, B., Kudom, A., Kuipers, E., Kulkarni, V., Kumar, G., Kwan, G., Lal, A., Lal, D., Lalloo, R., Lam, H., Lam, J., Langan, S., Lansingh, V., Larsson, A., Laryea, D., Latif, A., Lawrynowicz, A., Leigh, J., Levi, M., Li, Y., Lindsay, M., Lipshultz, S., Liu, P., Liu, S., Liu, Y., Lo, L., Logroscino, G., Lotufo, P., Lucas, R., Lunevicius, R., Lyons, R., Ma, S., Pedro Machado, V., Mackay, M., MacLachlan, J., Abd El Razek, H., Abd El Razek, M., Majdan, M., Majeed, A., Malekzadeh, R., Ayele Manamo, W., Mandisarisa, J., Mangalam, S., Mapoma, C., Marcenes, W., Margolis, D., Martin, G., Martinez-Raga, J., Marzan, M., Masiye, F., Mason-Jones, A., Massano, J., Matzopoulos, R., Mayosi, B., McGarvey, S., McGrath, J., Mckee, M., McMahon, B., Meaney, P., Mehari, A., Mehndiratta, M., Mena-Rodriguez, F., Mekonnen, A., Melaku, Y., Memiah, P., Memish, Z., Mendoza, W., Meretoja, A., Meretoja, T., Mhimbira, F., Micha, R., Miller, Ted, Mirarefin, M., Misganaw, A., Mock, C., Abdulmuhsin Mohammad, K., Mohammadi, A., Mohammed, S., Mohan, V., Mola, G., Monasta, L., Montanez Hernandez, J., Montero, P., Montico, M., Montine, T., Moradi-Lakeh, M., Morawska, L., Morgan, K., Mori, R., Mozaffarian, D., Mueller, U., Satyanarayana Murthy, G., Murthy, S., Musa, K., Nachega, J., Nagel, G., Naidoo, K., Naik, N., Naldi, L., Nangia, V., Nash, D., Nejjari, C., Neupane, S., Newton, C., Newton, J., Ng, M., Ngalesoni, F., Ngirabega, J., Quyen, L., Nisar, M., Nkamedjie Pete, P., Nomura, M., Norheim, O., Norman, P., Norrving, B., Nyakarahuka, L., Ogbo, F., Ohkubo, T., Ojelabi, F., Olivares, P., Olusanya, B., Olusanya, J., Opio, J., Oren, E., Ortiz, A., Osman, M., Ota, E., Ozdemir, R., Pa, M., Pandian, J., Pant, P., Papachristou, C., Park, E., Park, J., Parry, C., Parsaeian, M., Caicedo, A., Patten, S., Patton, G., Paul, V., Pearce, N., Pedro, J., Stokic, L., Pereira, D., Perico, N., Pesudovs, K., Petzold, M., Phillips, M., Piel, F., Pillay, J., Plass, D., Platts-Mills, J., Polinder, S., Pope, C., Popova, S., Poulton, R., Pourmalek, F., Prabhakaran, D., Qorbani, M., Quame-Amaglo, J., Quistberg, D., Rafay, A., Rahimi, K., Rahimi-Movaghar, V., Rahman, M., Rahman, S., Rai, R., Rajavi, Z., Rajsic, S., Raju, M., Rakovac, I., Rana, S., Ranabhat, C., Rangaswamy, T., Rao, P., Rao, S., Refaat, A., Rehm, J., Reitsma, M., Remuzzi, G., Resnikofff, S., Ribeiro, A., Ricci, S., Blancas, M., Roberts, B., Roca, A., Rojas-Rueda, D., Ronfani, L., Roshandel, G., Rothenbacher, D., Roy, A., Roy, N., Ruhago, G., Sagar, R., Saha, S., Sahathevan, R., Saleh, M., Sanabria, J., Sanchez-Nino, M., Sanchez-Riera, L., Santos, I., Sarmiento-Suarez, R., Sartorius, B., Satpathy, M., Savic, M., Sawhney, M., Schaub, M., Schmidt, M., Schneider, I., Schottker, B., Schutte, A., Schwebel, D., Seedat, S., Sepanlou, S., Servan-Mori, E., Shackelford, K., Shaddick, G., Shaheen, A., Shahraz, S., Shaikh, M., Shakh-Nazarova, M., Sharma, R., She, J., Sheikhbahaei, S., Shen, J., Shen, Z., Shepard, D., Sheth, K., Shetty, B., Shi, P., Shibuya, K., Shin, M., Shiri, R., Shiue, I., Shrime, M., Sigfusdottir, I., Silberberg, D., Silva, D., Silveira, D., Silverberg, J., Simard, E., Singh, A., Singh, G., Singh, J., Singh, O., Singh, P., Singh, V., Soneji, S., Soreide, K., Soriano, J., Sposato, L., Sreeramareddy, C., Stathopoulou, V., Stein, D., Stein, M., Stranges, S., Stroumpoulis, K., Sunguya, B., Sur, P., Swaminathan, S., Sykes, B., Szoeke, C., Tabares-Seisdedos, R., Tabb, K., Takahashi, K., Takala, J., Talongwa, R., Tandon, N., Tavakkoli, M., Taye, B., Taylor, H., Ao, B., Tedla, B., Tefera, W., Ten Have, M., Terkawi, A., Tesfay, F., Tessema, G., Thomson, A., Thorne-Lyman, A., Thrift, A., Thurston, G., Tillmann, T., Tirschwell, D., Tonelli, M., Topor-Madry, R., Topouzis, F., Nx, J., Traebert, J., Tran, B., Truelsen, T., Trujillo, U., Tura, A., Tuzcu, E., Uchendu, U., Ukwaja, K., Undurraga, E., Uthman, O., Van Dingenen, R., Van Donkelaar, A., Vasankari, T., Vasconcelos, A., Venketasubramanian, N., Vidavalur, R., Vijayakumar, L., Villalpando, S., Violante, F., Vlassov, V., Wagner, J., Wagner, G., Wallin, M., Wang, L., Watkins, D., Weichenthal, S., Weiderpass, E., Weintraub, R., Werdecker, A., Westerman, R., White, R., Wijeratne, T., Wilkinson, J., Williams, H., Wiysonge, C., Woldeyohannes, S., Wolfe, C., Won, S., Wong, J., Woolf, A., Xavier, D., Xiao, Q., Xu, G., Yakob, B., Yalew, A., Yan, L., Yano, Y., Yaseri, M., Ye, P., Yebyo, H., Yip, P., Yirsaw, B., Yonemoto, N., Yonga, G., Younis, M., Yu, S., Zaidi, Z., Zaki, M., Zannad, F., Zavala, D., Zeeb, H., Zeleke, B., Zhang, H., Zodpey, S., Zonies, D., Zuhlke, L., Vos, T., Lopez, A., and Murray, C.

Published
2016

34. Global, regional, and national disability-adjusted life-years (DALYs) for 315 diseases and injuries and healthy life expectancy (HALE), 1990-2015: a systematic analysis for the Global Burden of Disease Study 2015

Author

Kassebaum, N., Arora, M., Barber, R., Bhutta, Z., Carter, A., Casey, D., Charlson, F., Coates, M., Coggeshall, M., Cornaby, L., Dandona, L., Dicker, D., Erskine, H., Ferrari, A., Fitzmaurice, C., Foreman, K., Forouzanfar, M., Fullman, N., Gething, P., Goldberg, E., Graetz, N., Haagsma, J., Johnson, C., Kemmer, L., Khalil, I., Kinfu, Y., Kutz, M., Kyu, H., Leung, J., Liang, X., Lim, S., Lozano, R., Mensah, G., Mikesell, J., Mokdad, A., Mooney, M., Naghavi, M., Nguyen, G., Nsoesie, E., Pigott, D., Pinho, C., Rankin, Z., Reinig, N., Salomon, J., Sandar, L., Smith, A., Sorensen, R., Stanaway, J., Steiner, C., Teeple, S., Thomas, B., Troeger, C., VanderZanden, A., Wagner, J., Wanga, V., Whiteford, H., Zhou, M., Zoeckler, L., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abraham, B., Abubakar, I., Abu-Raddad, L., Abu-Rmeileh, N., Achoki, T., Ackerman, I., Adebiyi, A., Adedeji, I., Adsuar, J., Afanvi, K., Afshin, A., Agardh, E., Agarwal, A., Kumar, S., Ahmed, M., Kiadaliri, A., Ahmadieh, H., Akseer, N., Al-Aly, Z., Alam, K., Alam, N., Aldhahri, S., Alegretti, M., Aleman, A., Alemu, Z., Alexander, L., Raghib, A., Alkerwi, A., Alla, F., Allebeck, P., Alsharif, U., Altirkawi, K., Martin, E., Alvis-Guzman, N., Amare, A., Amberbir, A., Amegah, A., Amini, H., Ammar, W., Amrock, S., Anderson, G., Anderson, B., Antonio, C., Anwari, P., Arnlov, J., Arsenijevic, V., Artaman, A., Asayesh, H., Asghar, R., Avokpaho, E., Awasthi, A., Quintanilla, B., Azzopardi, P., Bacha, U., Badawi, A., Balakrishnan, K., Banerjee, A., Barac, A., Barker-Collo, S., Barnighausen, T., Barregard, L., Barrero, L., Basu, S., Bayou, T., Beardsley, J., Bedi, N., Beghi, E., Bell, B., Bell, M., Benjet, C., Bennett, D., Bensenor, I., Berhane, A., Bernabe, E., Betsu, B., Beyene, A., Bhala, N., Bhansali, A., Bhatt, S., Biadgilign, S., Bienhofff, K., Bikbov, B., Bin Abdulhak, A., Bisanzio, D., Bjertness, E., Blore, J., Borschmann, R., Boufous, S., Bourne, R., Brainin, M., Brazinova, A., Breitborde, N., Brugha, T., Buchbinder, R., Buckle, G., Butt, Z., Calabria, B., Campos-Nonato, I., Campuzano, J., Carabin, H., Carapetis, J., Cardenas, R., Carrero, J., Castaneda-Orjuela, C., Rivas, J., Catala-Lopez, F., Cavalleri, F., Chang, J., Chiang, P., Chibalabala, M., Chibueze, C., Chisumpa, V., Choi, J., Choudhury, L., Christensen, H., Ciobanu, L., Colistro, V., Colomar, M., Colquhoun, S., Cortinovis, M., Crump, J., Damasceno, A., Dandona, R., Dargan, P., Das Neves, J., Davey, G., Davis, A., De Leo, D., Degenhardt, L., Del Gobbo, L., Derrett, S., Des Jarlais, D., Deveber, G., Dharmaratne, S., Dhillon, P., Ding, E., Doyle, K., Driscoll, T., Duan, L., Dubey, M., Duncan, B., Ebrahimi, H., Ellenbogen, R., Elyazar, I., Endries, A., Ermakov, S., Eshrati, B., Esteghamati, A., Estep, K., Fahimi, S., Farid, T., Sa Farinha, C., Faro, A., Farvid, M., Farzadfar, F., Feigin, V., Fereshtehnejad, S., Fernandes, J., Fischer, F., Fitchett, J., Foigt, N., Fowkes, F., Franklin, R., Friedman, J., Frostad, J., Furst, T., Futran, N., Gabbe, B., Gankpe, F., Garcia-Basteiro, A., Gebrehiwot, T., Gebremedhin, A., Geleijnse, J., Gibney, K., Gillum, R., Ginawi, I., Giref, A., Giroud, M., Gishu, M., Godwin, W., Gomez-Dantes, H., Gona, P., Goodridge, A., Gopalani, S., Gotay, C., Goto, A., Gouda, H., Guo, Y., Gupta, R., Gupta, V., Gutierrez, R., Hafezi-Nejad, N., Haile, D., Hailu, A., Hailu, G., Halasa, Y., Ribhi, R., Hamadeh, Hamidi, S., Hammami, M., Handal, A., Hankey, G., Harb, H., Harikrishnan, S., Haro, J., Hassanvand, M., Hassen, T., Havmoeller, R., Hay, R., Hedayati, M., Heredia-Pi, I., Heydarpour, P., Hoek, H., Hoffman, D., Horino, M., Horita, N., Hosgood, H., Hoy, D., Hsairi, M., Huang, H., Huang, J., Iburg, K., Idrisov, B., Innos, K., Inoue, M., Jacobsen, K., Jauregui, A., Jayatilleke, A., Jeemon, P., Jha, V., Jiang, G., Jiang, Y., Jibat, T., Jimenez-Corona, A., Jin, Y., Jonas, J., Kabir, Z., Kajungu, D., Kalkonde, Y., Kamal, R., Kan, H., Kandel, A., Karch, A., Karema, C., Karimkhani, C., Kasaeian, A., Katibeh, M., Kaul, A., Kawakami, N., Kazi, D., Keiyoro, P., Kemp, A., Kengne, A., Keren, A., Kesavachandran, C., Khader, Y., Khan, A., Khan, E., Khang, Y., Khoja, T., Khubchandani, J., Kieling, C., Kim, C., Kim, D., Kim, Y., Kissoon, N., Kivipelto, M., Knibbs, L., Knudsen, A., Kokubo, Y., Kolte, D., Kopec, J., Koul, P., Koyanagi, A., Defo, B., Kuchenbecker, R., Bicer, B., Kuipers, E., Kumar, G., Kwan, G., Lalloo, R., Lallukka, T., Larsson, A., Latif, A., Lavados, P., Lawrynowicz, A., Leasher, J., Leigh, J., Leung, R., Li, Y., Lipshultz, S., Liu, P., Liu, Y., Lloyd, B., Logroscino, G., Looker, K., Lotufo, P., Lucas, R., Lunevicius, R., Lyons, R., El Razek, H., Mandavi, M., Majdan, M., Majeed, A., Malekzadeh, R., Malta, D., Marcenes, W., Martinez-Raga, J., Masiye, F., Mason-Jones, A., Matzopoulos, R., Mayosi, B., McGrath, J., Mckee, M., Meaney, P., Mehari, A., Melaku, Y., Memiah, P., Memish, Z., Mendoza, W., Meretoja, A., Meretoja, T., Mesfin, Y., Mhimbira, F., Miller, Ted, Mills, E., Mirarefin, M., Mirrakhimov, E., Mitchell, P., Mock, C., Mohammad, K., Mohammadi, A., Mohammed, S., Monasta, L., Montanez Hernandez, J., Montico, M., Moradi-Lakeh, M., Mori, R., Mueller, U., Mumford, J., Murdoch, M., Murthy, G., Nachega, J., Naheed, A., Naldi, L., Nangia, V., Newton, J., Ng, M., Ngalesoni, F., Le Nguyen, Q., Nisar, M., Pete, P., Nolla, J., Norheim, O., Norman, R., Norrving, B., Obermeyer, C., Ogbo, F., Oh, I., Oladimeji, O., Olivares, P., Olusanya, B., Olusanya, J., Oren, E., Ortiz, A., Ota, E., Oyekale, A., Pa, M., Park, E., Parsaeian, M., Patten, S., Patton, G., Pedro, J., Pereira, D., Perico, N., Pesudovs, K., Petzold, M., Phillips, M., Piel, F., Pillay, J., Pishgar, F., Plass, D., Polinder, S., Popova, S., Poulton, R., Pourmalek, F., Prasad, N., Qorbani, M., Rabiee, R., Radfar, A., Rafay, A., Rahimi, K., Rahimi-Movaghar, V., Rahman, M., Rahman, S., Rai, D., Rai, R., Rajsic, S., Raju, M., Ram, U., Ranganathan, K., Refaat, A., Reitsma, M., Remuzzi, G., Resnikoff, S., Reynolds, A., Ribeiro, A., Ricci, S., Roba, H., Rojas-Rueda, D., Ronfani, L., Roshandel, G., Roth, G., Roy, A., Sackey, B., Sagar, R., Sanabria, J., Dolores Sanchez-Nino, M., Santos, I., Santos, J., Sarmiento-Suarez, R., Sartorius, B., Satpathy, M., Savic, M., Sawhney, M., Schmidt, M., Schneider, I., Schutte, A., Schwebel, D., Seedat, S., Sepanlou, S., Servan-Mori, E., Shahraz, S., Shaikh, M., Sharma, R., She, J., Sheikhbahaei, S., Shen, J., Sheth, K., Shibuya, K., Shigematsu, M., Shin, M., Shin, R., Sigfusdottir, I., Santos Silva, D., Silverberg, J., Simard, E., Singh, A., Singh, J., Singh, P., Skirbekk, V., Skogen, J., Soljak, M., Soreide, K., Sreeramareddy, C., Stathopoulou, V., Steel, N., Stein, D., Stein, M., Steiner, T., Stovner, L., Stranges, S., Stroumpoulis, K., Sunguya, B., Sur, P., Swaminathan, S., Sykes, B., Szoeke, C., Tabares-Seisdedos, R., Landon, N., Tanne, D., Tavakkoli, M., Taye, B., Taylor, H., Ao, B., Tegegne, T., Tekle, D., Terkawi, A., Tessema, G., Thakur, J., Thomson, A., Thorne-Lyman, A., Thrift, A., Thurston, G., Tobe-Gai, R., Tonelli, M., Topor-Madry, R., Topouzis, F., Tran, B., Dimbuene, Z., Tsilimbaris, M., Tura, A., Tuzcu, E., Tyrovolas, S., Ukwaja, K., Undurraga, E., Uneke, C., Uthman, O., van Gool, C., van Os, J., Vasankari, T., Vasconcelos, A., Venketasubramanian, N., Violante, F., Vlassov, V., Vollset, S., Wagner, G., Wallin, M., Wang, L., Weichenthal, S., Weiderpass, E., Weintraub, R., Werdecker, A., WestermaM, R., Wijeratne, T., Wilkinson, J., Williams, H., Wiysonge, C., Woldeyohannes, S., Wolfe, C., Won, S., Xu, G., Yadav, A., Yakob, B., Yan, L., Yan, Y., Yaseri, M., Ye, P., Yip, P., Yonemoto, N., Yoon, S., Younis, M., Yu, C., Zaidi, Z., Zaki, M., Zeeb, H., Zodpey, S., Zonies, D., Zuhlke, L., Vos, T., Lopez, A., Murray, C., Kassebaum, N., Arora, M., Barber, R., Bhutta, Z., Carter, A., Casey, D., Charlson, F., Coates, M., Coggeshall, M., Cornaby, L., Dandona, L., Dicker, D., Erskine, H., Ferrari, A., Fitzmaurice, C., Foreman, K., Forouzanfar, M., Fullman, N., Gething, P., Goldberg, E., Graetz, N., Haagsma, J., Johnson, C., Kemmer, L., Khalil, I., Kinfu, Y., Kutz, M., Kyu, H., Leung, J., Liang, X., Lim, S., Lozano, R., Mensah, G., Mikesell, J., Mokdad, A., Mooney, M., Naghavi, M., Nguyen, G., Nsoesie, E., Pigott, D., Pinho, C., Rankin, Z., Reinig, N., Salomon, J., Sandar, L., Smith, A., Sorensen, R., Stanaway, J., Steiner, C., Teeple, S., Thomas, B., Troeger, C., VanderZanden, A., Wagner, J., Wanga, V., Whiteford, H., Zhou, M., Zoeckler, L., Abajobir, A., Abate, K., Abbafati, C., Abbas, K., Abd-Allah, F., Abraham, B., Abubakar, I., Abu-Raddad, L., Abu-Rmeileh, N., Achoki, T., Ackerman, I., Adebiyi, A., Adedeji, I., Adsuar, J., Afanvi, K., Afshin, A., Agardh, E., Agarwal, A., Kumar, S., Ahmed, M., Kiadaliri, A., Ahmadieh, H., Akseer, N., Al-Aly, Z., Alam, K., Alam, N., Aldhahri, S., Alegretti, M., Aleman, A., Alemu, Z., Alexander, L., Raghib, A., Alkerwi, A., Alla, F., Allebeck, P., Alsharif, U., Altirkawi, K., Martin, E., Alvis-Guzman, N., Amare, A., Amberbir, A., Amegah, A., Amini, H., Ammar, W., Amrock, S., Anderson, G., Anderson, B., Antonio, C., Anwari, P., Arnlov, J., Arsenijevic, V., Artaman, A., Asayesh, H., Asghar, R., Avokpaho, E., Awasthi, A., Quintanilla, B., Azzopardi, P., Bacha, U., Badawi, A., Balakrishnan, K., Banerjee, A., Barac, A., Barker-Collo, S., Barnighausen, T., Barregard, L., Barrero, L., Basu, S., Bayou, T., Beardsley, J., Bedi, N., Beghi, E., Bell, B., Bell, M., Benjet, C., Bennett, D., Bensenor, I., Berhane, A., Bernabe, E., Betsu, B., Beyene, A., Bhala, N., Bhansali, A., Bhatt, S., Biadgilign, S., Bienhofff, K., Bikbov, B., Bin Abdulhak, A., Bisanzio, D., Bjertness, E., Blore, J., Borschmann, R., Boufous, S., Bourne, R., Brainin, M., Brazinova, A., Breitborde, N., Brugha, T., Buchbinder, R., Buckle, G., Butt, Z., Calabria, B., Campos-Nonato, I., Campuzano, J., Carabin, H., Carapetis, J., Cardenas, R., Carrero, J., Castaneda-Orjuela, C., Rivas, J., Catala-Lopez, F., Cavalleri, F., Chang, J., Chiang, P., Chibalabala, M., Chibueze, C., Chisumpa, V., Choi, J., Choudhury, L., Christensen, H., Ciobanu, L., Colistro, V., Colomar, M., Colquhoun, S., Cortinovis, M., Crump, J., Damasceno, A., Dandona, R., Dargan, P., Das Neves, J., Davey, G., Davis, A., De Leo, D., Degenhardt, L., Del Gobbo, L., Derrett, S., Des Jarlais, D., Deveber, G., Dharmaratne, S., Dhillon, P., Ding, E., Doyle, K., Driscoll, T., Duan, L., Dubey, M., Duncan, B., Ebrahimi, H., Ellenbogen, R., Elyazar, I., Endries, A., Ermakov, S., Eshrati, B., Esteghamati, A., Estep, K., Fahimi, S., Farid, T., Sa Farinha, C., Faro, A., Farvid, M., Farzadfar, F., Feigin, V., Fereshtehnejad, S., Fernandes, J., Fischer, F., Fitchett, J., Foigt, N., Fowkes, F., Franklin, R., Friedman, J., Frostad, J., Furst, T., Futran, N., Gabbe, B., Gankpe, F., Garcia-Basteiro, A., Gebrehiwot, T., Gebremedhin, A., Geleijnse, J., Gibney, K., Gillum, R., Ginawi, I., Giref, A., Giroud, M., Gishu, M., Godwin, W., Gomez-Dantes, H., Gona, P., Goodridge, A., Gopalani, S., Gotay, C., Goto, A., Gouda, H., Guo, Y., Gupta, R., Gupta, V., Gutierrez, R., Hafezi-Nejad, N., Haile, D., Hailu, A., Hailu, G., Halasa, Y., Ribhi, R., Hamadeh, Hamidi, S., Hammami, M., Handal, A., Hankey, G., Harb, H., Harikrishnan, S., Haro, J., Hassanvand, M., Hassen, T., Havmoeller, R., Hay, R., Hedayati, M., Heredia-Pi, I., Heydarpour, P., Hoek, H., Hoffman, D., Horino, M., Horita, N., Hosgood, H., Hoy, D., Hsairi, M., Huang, H., Huang, J., Iburg, K., Idrisov, B., Innos, K., Inoue, M., Jacobsen, K., Jauregui, A., Jayatilleke, A., Jeemon, P., Jha, V., Jiang, G., Jiang, Y., Jibat, T., Jimenez-Corona, A., Jin, Y., Jonas, J., Kabir, Z., Kajungu, D., Kalkonde, Y., Kamal, R., Kan, H., Kandel, A., Karch, A., Karema, C., Karimkhani, C., Kasaeian, A., Katibeh, M., Kaul, A., Kawakami, N., Kazi, D., Keiyoro, P., Kemp, A., Kengne, A., Keren, A., Kesavachandran, C., Khader, Y., Khan, A., Khan, E., Khang, Y., Khoja, T., Khubchandani, J., Kieling, C., Kim, C., Kim, D., Kim, Y., Kissoon, N., Kivipelto, M., Knibbs, L., Knudsen, A., Kokubo, Y., Kolte, D., Kopec, J., Koul, P., Koyanagi, A., Defo, B., Kuchenbecker, R., Bicer, B., Kuipers, E., Kumar, G., Kwan, G., Lalloo, R., Lallukka, T., Larsson, A., Latif, A., Lavados, P., Lawrynowicz, A., Leasher, J., Leigh, J., Leung, R., Li, Y., Lipshultz, S., Liu, P., Liu, Y., Lloyd, B., Logroscino, G., Looker, K., Lotufo, P., Lucas, R., Lunevicius, R., Lyons, R., El Razek, H., Mandavi, M., Majdan, M., Majeed, A., Malekzadeh, R., Malta, D., Marcenes, W., Martinez-Raga, J., Masiye, F., Mason-Jones, A., Matzopoulos, R., Mayosi, B., McGrath, J., Mckee, M., Meaney, P., Mehari, A., Melaku, Y., Memiah, P., Memish, Z., Mendoza, W., Meretoja, A., Meretoja, T., Mesfin, Y., Mhimbira, F., Miller, Ted, Mills, E., Mirarefin, M., Mirrakhimov, E., Mitchell, P., Mock, C., Mohammad, K., Mohammadi, A., Mohammed, S., Monasta, L., Montanez Hernandez, J., Montico, M., Moradi-Lakeh, M., Mori, R., Mueller, U., Mumford, J., Murdoch, M., Murthy, G., Nachega, J., Naheed, A., Naldi, L., Nangia, V., Newton, J., Ng, M., Ngalesoni, F., Le Nguyen, Q., Nisar, M., Pete, P., Nolla, J., Norheim, O., Norman, R., Norrving, B., Obermeyer, C., Ogbo, F., Oh, I., Oladimeji, O., Olivares, P., Olusanya, B., Olusanya, J., Oren, E., Ortiz, A., Ota, E., Oyekale, A., Pa, M., Park, E., Parsaeian, M., Patten, S., Patton, G., Pedro, J., Pereira, D., Perico, N., Pesudovs, K., Petzold, M., Phillips, M., Piel, F., Pillay, J., Pishgar, F., Plass, D., Polinder, S., Popova, S., Poulton, R., Pourmalek, F., Prasad, N., Qorbani, M., Rabiee, R., Radfar, A., Rafay, A., Rahimi, K., Rahimi-Movaghar, V., Rahman, M., Rahman, S., Rai, D., Rai, R., Rajsic, S., Raju, M., Ram, U., Ranganathan, K., Refaat, A., Reitsma, M., Remuzzi, G., Resnikoff, S., Reynolds, A., Ribeiro, A., Ricci, S., Roba, H., Rojas-Rueda, D., Ronfani, L., Roshandel, G., Roth, G., Roy, A., Sackey, B., Sagar, R., Sanabria, J., Dolores Sanchez-Nino, M., Santos, I., Santos, J., Sarmiento-Suarez, R., Sartorius, B., Satpathy, M., Savic, M., Sawhney, M., Schmidt, M., Schneider, I., Schutte, A., Schwebel, D., Seedat, S., Sepanlou, S., Servan-Mori, E., Shahraz, S., Shaikh, M., Sharma, R., She, J., Sheikhbahaei, S., Shen, J., Sheth, K., Shibuya, K., Shigematsu, M., Shin, M., Shin, R., Sigfusdottir, I., Santos Silva, D., Silverberg, J., Simard, E., Singh, A., Singh, J., Singh, P., Skirbekk, V., Skogen, J., Soljak, M., Soreide, K., Sreeramareddy, C., Stathopoulou, V., Steel, N., Stein, D., Stein, M., Steiner, T., Stovner, L., Stranges, S., Stroumpoulis, K., Sunguya, B., Sur, P., Swaminathan, S., Sykes, B., Szoeke, C., Tabares-Seisdedos, R., Landon, N., Tanne, D., Tavakkoli, M., Taye, B., Taylor, H., Ao, B., Tegegne, T., Tekle, D., Terkawi, A., Tessema, G., Thakur, J., Thomson, A., Thorne-Lyman, A., Thrift, A., Thurston, G., Tobe-Gai, R., Tonelli, M., Topor-Madry, R., Topouzis, F., Tran, B., Dimbuene, Z., Tsilimbaris, M., Tura, A., Tuzcu, E., Tyrovolas, S., Ukwaja, K., Undurraga, E., Uneke, C., Uthman, O., van Gool, C., van Os, J., Vasankari, T., Vasconcelos, A., Venketasubramanian, N., Violante, F., Vlassov, V., Vollset, S., Wagner, G., Wallin, M., Wang, L., Weichenthal, S., Weiderpass, E., Weintraub, R., Werdecker, A., WestermaM, R., Wijeratne, T., Wilkinson, J., Williams, H., Wiysonge, C., Woldeyohannes, S., Wolfe, C., Won, S., Xu, G., Yadav, A., Yakob, B., Yan, L., Yan, Y., Yaseri, M., Ye, P., Yip, P., Yonemoto, N., Yoon, S., Younis, M., Yu, C., Zaidi, Z., Zaki, M., Zeeb, H., Zodpey, S., Zonies, D., Zuhlke, L., Vos, T., Lopez, A., and Murray, C.

Published
2016

36. Expression of 19 microRNAs in glioblastoma and comparison with other brain neoplasia of grades I-III

Author

Visani, M, de Biase, D, Marucci, G, Cerasoli, S, Nigrisoli, E, Bacchi Reggiani ML, Albani, F, Baruzzi, A, Pession, A, Calbucci, F, D'Alessandro, R, Michelucci, R, Brandes, A, Eusebi, V, Ceruti, S, Fainardi, E, Tamarozzi, R, Emiliani, E, Cavallo, M, Franceschi, E, Tosoni, A, Fiorica, F, Valentini, A, Depenni, R, Mucciarini, C, Crisi, G, Sasso, E, Biasini, C, Cavanna, L, Guidetti, D, Marcello, N, Pisanello, A, Cremonini, Am, Guiducci, G, Agati, R, Ambrosetto, G, Bacci, A, Baldin, E, Baldrati, A, Barbieri, E, Bartolini, S, Bellavista, E, Bisulli, F, Bonora, E, Bunkheila, F, Carelli, V, Crisci, M, Dall'Occa, P, Ferro, S, Franceschi, C, Frezza, G, Grasso, V, Leonardi, M, Morandi, L, Mostacci, B, Palandri, G, Pasini, E, Pastore Trossello, M, Poggi, R, Riguzzi, P, Rinaldi, R, Rizzi, S, Romeo, G, Spagnolli, F, Tinuper, P, Trocino, C, Dall'Agata, M, Frattarelli, M, Gentili, G, Giovannini, A, Iorio, P, Pasquini, U, Galletti, G, Guidi, C, Neri, W, Patuelli, A, Strumia, S, Faedi, M, Casmiro, M, Gamboni, A, Rasi, F, Cruciani, G, Cenni, P, Dazzi, C, Guidi, Ar, Zumaglini, F, Amadori, A, Pasini, G, Pasquinelli, M, Pasquini, E, Polselli, A, Ravasio, A, Viti, B, Sintini, M, Ariatti, A, Bertolini, F, Bigliardi, G, Carpeggiani, P, Cavalleri, F, Meletti, S, Nichelli, P, Pettorelli, E, Pinna, G, Zunarelli, E, Artioli, F, Bernardini, I, Costa, M, Greco, G, Guerzoni, R, Stucchi, C, Iaccarino, C, Ragazzi, M, Rizzi, R, Zuccoli, G, Api, P, Cartei, F, Fallica, E, Granieri, E, Latini, F, Lelli, G, Monetti, C, Saletti, A, Schivalocchi, R, Seraceni, S, Tola, Mr, Urbini, B, Giorgi, C, Montanari, E, Cerasti, D, Crafa, P, Dascola, I, Florindo, I, Giombelli, E, Mazza, S, Ramponi, V, Servadei, F, Silini, Em, Torelli, P, Immovilli, P, Morelli, N, Vanzo, C, Nobile, C, Michela Visani, Dario de Biase, Gianluca Marucci, Serenella Cerasoli, Evandro Nigrisoli, Maria Letizia Bacchi Reggiani, Fiorenzo Albani, Agostino Baruzzi, Annalisa Pession, the PERNO study group [, Elena Bonora, and ]

Subjects
Adult, Male, Cancer Research, Low-grade brain tumor, Brain neoplasia, Glioblastoma, Low-grade brain tumors, MicroRNA, Real-time PCR, Aged, Brain Neoplasms, Female, Gene Expression Profiling, Humans, MicroRNAs, Middle Aged, Neoplasm Grading, RNA, Neoplasm, Gene Expression Regulation, Neoplastic, Genetics, Molecular Medicine, Biology, Bioinformatics, medicine.disease_cause, NO, Brain Neoplasm, Genetic, microRNA, medicine, Locked nucleic acid, MicroRNA, Glioblastoma, Brain neoplasia, Low-grade brain tumors, Real-time PCR, Cancer, General Medicine, medicine.disease, Molecular medicine, Fold change, Gene expression profiling, Real-time polymerase chain reaction, Oncology, Cancer research, Carcinogenesis, Corrigendum, Human
Abstract

Several biomarkers have been proposed as useful parameters to better specify the prognosis or to delineate new target therapy strategies for glioblastoma patients. MicroRNAs could represent putative target molecules, considering their role in tumorigenesis, cancer progression and their specific tissue expression. Although several studies have tried to identify microRNA signature for glioblastoma, a microRNA profile is still far from being well-defined. In this work the expression of 19 microRNAs (miR-7, miR-9, miR-9∗, miR-10a, miR-10b, miR-17, miR-20a, miR-21, miR-26a, miR-27a, miR-31, miR-34a, miR-101, miR-137, miR-182, miR-221, miR-222, miR-330, miR-519d) was evaluated in sixty formalin-fixed and paraffin-embedded glioblastoma samples using a locked nucleic acid real-time PCR. Moreover, a comparison of miRNA expressions was performed between primary brain neoplasias of different grades (grades IV-I). The analysis of 14 validated miRNA expression in the 60 glioblastomas, using three different non-neoplastic references as controls, revealed a putative miRNA signature: mir-10b and miR-21 were up-regulated, while miR-7, miR-31, miR-101, miR-137, miR-222 and miR-330 were down-regulated in glioblastomas. Comparing miRNA expression between glioblastoma group and gliomas of grades I-III, 3 miRNAs (miR-10b, mir-34a and miR-101) showed different regulation statuses between high-grade and low-grade tumors. miR-10b was up-regulated in high grade and significantly down-regulated in low-grade gliomas, suggesting that could be a candidate for a GBM target therapy. This study provides further data for the identification of a miRNA profile for glioblastoma and suggests that different-grade neoplasia could be characterized by different expression of specific miRNAs.

Published
2014

37. Intense immunosuppression followed by autologous stem cell transplantation in severe multiple sclerosis

Author

Capello E, Saccardi R, Murialdo A, Gualandi F, Pagliai F, Bacigalupo A, Marmont A, Uccelli A, Inglese M, Bruzzi P, Sormani MP, Cocco E, Meucci G, Massacesi L, Bertolotto A, Lugaresi A, Merelli E, Solari A, Filippi M, Mancardi GL, Italian GITMO-Neuro Intergroup on ASCT for Multiple Sclerosis, La Nasa G, Marrosu MG, Derchi V, Di Bartolomeo P, Farina D, Iarlori C, Tartaro A, Repice A, Pellicanò G, Dogliotti L, Parodi RC, Schenone A, Donelli A, Casoni F, Cavalleri F, Capobianco M, Guerrasio A, Duca S, Papineschi F, Scappini B, Mosti S, Abbruzzese A, Capello, E, Saccardi, R, Murialdo, A, Gualandi, F, Pagliai, F, Bacigalupo, A, Marmont, A, Uccelli, A, Inglese, M, Bruzzi, P, Sormani, Mp, Cocco, E, Meucci, G, Massacesi, L, Bertolotto, A, Lugaresi, A, Merelli, E, Solari, A, Filippi, M, Mancardi, Gl, Italian GITMO-Neuro Intergroup on ASCT for Multiple, Sclerosi, La Nasa, G, Marrosu, Mg, Derchi, V, Di Bartolomeo, P, Farina, D, Iarlori, C, Tartaro, A, Repice, A, Pellicanò, G, Dogliotti, L, Parodi, Rc, Schenone, A, Donelli, A, Casoni, F, Cavalleri, F, Capobianco, M, Guerrasio, A, Duca, S, Papineschi, F, Scappini, B, Mosti, S, and Abbruzzese, A

Subjects
Oncology, Adult, medicine.medical_specialty, Multiple Sclerosis, medicine.medical_treatment, Inflammation, Dermatology, Transplantation, Autologous, Severity of Illness Index, methods, Autologous stem-cell transplantation, Internal medicine, medicine, Humans, Severe disability, Salvage Therapy, Transplantation, Adult, Hematopoietic Stem Cell Transplantation, methods, Humans, Immunosuppressive Agents, therapeutic use, Italy, Magnetic Resonance Imaging, Multiple Sclerosis, diagnosis/immunology/therapy, Salvage Therapy, Severity of Illness Index, Transplantation, Autologous, Treatment Outcome, business.industry, Multiple sclerosis, Hematopoietic Stem Cell Transplantation, diagnosis/immunology/therapy, Immunosuppression, General Medicine, medicine.disease, Magnetic Resonance Imaging, Psychiatry and Mental health, Haematopoiesis, Treatment Outcome, Italy, therapeutic use, Neurology (clinical), medicine.symptom, Stem cell, business, Autologous, Immunosuppressive Agents
Abstract

Aggressive forms of multiple sclerosis (MS) represent a limited group of demyelinating diseases that rapidly progress to severe disability. Currently available therapies are poorly effective against these clinical entities. Recently, it has been demonstrated that intense immunosuppression followed by autologous haematopoietic stem cell transplantation (AHSCT) can affect the clinical course of individuals with severe MS and completely abrogate the inflammatory activity detected by MRI. We report the result of the Italian phase 2 GITMO study, a multicentre study in which 21 MS patients, who were rapidly deteriorating and not responding to the usual therapeutic strategies, were treated with this procedure. The clinical effect of the treatment is long lasting, with a striking abrogation of inflammation detected by MRI findings. These results support a role for intense immunosuppression followed by ASCT as treatment in rapidly evolving MS cases unresponsive to conventional therapies.

Published
2005

38. Erratum to: Survival prediction in high-grade gliomas using CT perfusion imaging

Author

Yeung, Tp, Wang, Y, He, W, Urbini, B, Gafà, R, Ulazzi, L, Yartsev, S, Bauman, G, Lee TY, Fainardi, E, Project of Emilia-Romagna Region on Neuro-Oncology (PERNO) Study Group Participants :Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall’Occa, P., de Biase, D., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Marucci, G., Morandi, L., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Pession, A., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., (Bologna), Trocino C., Dall’Agata, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., (Forlı`-Cesena), Strumia S., Faedi, M., (IRCCS Istituto Scientifico Romagnolo per lo Studio, e la Cura dei Tumori), Casmiro, M., Gamboni, A., Rasi, F. (Faenza R. A. )., (Lugo, Cruciani G., RA), Cenni, P., Dazzi, C., Guidi, A. R., (Ravenna), Zumaglini F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., (Rimini), Viti B., (Cattolica, Sintini M., RN), Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., (Modena), Zunarelli E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C. (Carpi M. O. )., Iaccarino, C, Ragazzi, M., Rizzi, R., (Istituto di Ricovero e Cura a Carattere Scientifico, Zuccoli G., Reggio, Emilia), Api, P., Cartei, F., Colella, M., Fallica, E., Farneti, M., Frassoldati, A., Granieri, E., Latini, F., Monetti, C., Saletti, A., Schivalocchi, R., Sarubbo, S., Seraceni, S., Tola, M. R., Urbini, B., (Ferrara), Zini G., Giorgi, C., Montanari, E. (Fidenza P. R. )., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, Em., (Parma), Torelli P., Immovilli, P., Morelli, N., (Piacenza), Vanzo C., and Nobile, C. (Padova).

Subjects
Cancer Research, medicine.medical_specialty, Neuroradiology unit, Neurology, Oncology, business.industry, General surgery, Medicine, Neurology (clinical), business
Abstract

Baruzzi A. (Chair), Albani F., Calbucci F., D’Alessandro R., Michelucci R. (IRCCS Institute of Neurological Sciences, Bologna, Italy), Brandes A. (Department of Medical Oncology, Bellaria-Maggiore Hospitals, Bologna, Italy), Eusebi V. (Department of Hematology and Oncological Sciences ‘‘L. & A. Seragnoli’’, Section of Anatomic Pathology at Bellaria Hospital, Bologna, Italy), Ceruti S., Fainardi E., Tamarozzi R. (Neuroradiology Unit, Department of Neurosciences and Rehabilitation, S. Anna Hospital, Ferrara, Italy), Emiliani E. (Istituto Oncologico Romagnolo, Department of Medical Oncology, Santa Maria delle Croci Hospital, Ravenna, Italy), Cavallo M. (Division of Neurosurgery, Department of Neurosciences and Rehabilitation, S. Anna Hospital, Ferrara, Italy).

Published
2015
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39. Definition of miRNAs Expression Profile in Glioblastoma Samples: The Relevance of Non-Neoplastic Brain Reference

Author

Visani, Michela, De Biase, Dario, Marucci, Gianluca, Taccioli, Cristian, Baruzzi, Agostino, Pession, Annalisa, Baruzzi, A., Albani, F., Calbucci, F., D'alessandro, R., Michelucci, R., Brandes, A., Eusebieusebi, V., Ceruti, S., Fainardi, E., Tamarozzi, R., Emiliani, E., Cavallo, M., Franceschi, E., Tosoni, A., Fiorica, F., Valentini, A., Depenni, R., Mucciarini, C., Crisi, G., Sasso, E., Biasini, C., Cavanna, L., Guidetti, D., Marcello, N., Pisanello, A., Cremonini, A. M., Guiducci, G., De Pasqua, S., Testoni, S., Agati, R., Ambrosetto, G., Bacci, A., Baldin, E., Baldrati, A., Barbieri, E., Bartolini, S., Bellavista, E., Bisulli, F., Bonora, E., Bunkheila, F., Carelli, V., Crisci, M., Dall'occa, P., Ferro, S., Franceschi, C., Frezza, G., Grasso, V., Leonardi, M., Mostacci, B., Palandri, G., Pasini, E., Pastore Trossello, M., Poggi, R., Riguzzi, P., Rinaldi, R., Rizzi, S., Romeo, G., Spagnolli, F., Tinuper, P., Trocino, C., Cerasoli, S., Dall'agata, M., Faedi, M., Frattarelli, M., Gentili, G., Giovannini, A., Iorio, P., Pasquini, U., Galletti, G., Guidi, C., Neri, W., Patuelli, A., Strumia, S., Casmiro, M., Gamboni, A., Rasi, F., Cruciani, G., Cenni, P., Dazzi, C., Guidi, A. R., Zumaglini, F., Amadori, A., Pasini, G., Pasquinelli, M., Pasquini, E., Polselli, A., Ravasio, A., Viti, B., Sintini, M., Ariatti, A., Bertolini, F., Bigliardi, G., Carpeggiani, P., Cavalleri, F., Meletti, S., Nichelli, P., Pettorelli, E., Pinna, G., Zunarelli, E., Artioli, F., Bernardini, I., Costa, M., Greco, G., Guerzoni, R., Stucchi, C., Iaccarino, C., Ragazzi, M., Rizzi, R., Zuccoli, G., Api, P., Cartei, F., Fallica, E., Granieri, E., Latini, F., Lelli, G., Monetti, C., Saletti, A., Schivalocchi, R., Seraceni, S., Tola, M. R., Urbini, B., Giorgi, C., Montanari, E., Cerasti, D., Crafa, P., Dascola, I., Florindo, I., Giombelli, E., Mazza, S., Ramponi, V., Servadei, F., Silini, E. M., Torelli, P., Immovilli, P., Morelli, N., Vanzo, C., Nobile, C., M. Visani, D. de Biase, G. Marucci, C. Taccioli, A. Baruzzi, A. Pession, Perno Study Group, F. Albani, V. Eusebi, F. Bisulli, V. Carelli, M. Leonardi, B. Mostacci, P. Tinuper, the PERNO Study group [, E. Bonora, and ]

Subjects
Male, Genetics and Molecular Biology (all), Adult, Aged, Brain, Female, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Glioblastoma, Humans, MicroRNAs, Middle Aged, Real-Time Polymerase Chain Reaction, Reference Values, Statistics, Nonparametric, Biochemistry, Genetics and Molecular Biology (all), Agricultural and Biological Sciences (all), Gene Expression, Bioinformatics, Biochemistry, Surgical oncology, Nucleic Acids, metabolism, Female, Gene Expression Profiling, Molecular Cell Biology, Basic Cancer Research, Gene expression, normal adjacent the tumor, Neurological Tumors, methods, Gene Expression Regulation, brain tumors, glioblastoma, miRNAs, Multidisciplinary, Cancer Risk Factors, Medicine (all), Statistics, non-neoplastic brain, Real-time polymerase chain reaction, Oncology, miRNAs, Medicine, DNA microarray, brain RNA commercial reference, Research Article, Adult, Aged, Brain, Neoplastic, genetics/physiology, Glioblastoma, metabolism, Humans, Male, MicroRNAs, metabolism, Middle Aged, Real-Time Polymerase Chain Reaction, Reference Values, Statistics, Nonparametric, Science, Brain tumor, Biology, NO, Molecular Genetics, epileptic tissue, Text mining, microRNA, medicine, miRNA, business.industry, Computational Biology, Cancers and Neoplasms, medicine.disease, Gene expression profiling, Gene Expression Regulation, Cancer research, RNA, brain tumors, metabolism, Middle Aged, Real-Time Polymerase Chain Reaction, Reference Values, Statistic, business, metabolism, Humans, Male, MicroRNA, Glioblastoma Multiforme
Abstract

Glioblastoma is the most aggressive brain tumor that may occur in adults. Regardless of the huge improvements in surgery and molecular therapy, the outcome of neoplasia remains poor. MicroRNAs are small molecules involved in several cellular processes, and their expression is altered in the vast majority of tumors. Several studies reported the expression of different miRNAs in glioblastoma, but one of the most critical point in understanding glioblastoma miRNAs profile is the comparison of these studies. In this paper, we focused our attention on the non-neoplastic references used for determining miRNAs expression. The aim of this study was to investigate if using three different non-neoplastic brain references (normal adjacent the tumor, commercial total RNA, and epileptic specimens) could provide discrepant results. The analysis of 19 miRNAs was performed using Real-Time PCR, starting from the set of samples described above and the expression values compared. Moreover, the three different normal RNAs were used to determine the miRNAs profile in 30 glioblastomas. The data showed that different non-neoplastic controls could lead to different results and emphasize the importance of comparing miRNAs profiles obtained using the same experimental condition.

Published
2013

42. GLIOMATOSIS CEREBRI: A SINGLE INSTITUTION REPORT

Author

Bertolini, Federica, Depenni, Roberta, Fontana, A., Falasca, A., Meletti, Stefano, Valentini, A., Giacobazzi, P., Cavalleri, F., Zunarelli, E., and Pinna, G. P.

Subjects
gliomatosis, epilepsy
Published
2009

43. The long-term effect of AHSCT on MRI measures of MS evolution: a five-year follow-up study

Author

Roccatagliata, L, Rocca, M, Valsasina, P, Bonzano, L, Sormani, M., Saccardi, R, Mancardi, G, Filippi, M, Marrosu, Mg, La Nasa, G, Cocco, E, Cherchi, V, Lugaresi, A, Di Bartolomeo, P, Farina, D, Ialori, C, Tartaro, A, Massacesi, L, Pagliai, F, Bosi, A, Repice, A, Konze, A, Sardanelli, F, Capello, E, Murialdo, A, Gualandi, F, Parodi, Rc, Dogliotti, L, Marmont, A, Inglese, M, Comi, G, Donelli, A, Merelli, E, Casoni, F, Cavalleri, F, Bertolotto, A, Guerrasio, A, Capobianco, M, Duca, S, Meucci, G, Papineschi, F, Mosti, S, and Abruzzese, A

Published
2007

45. IL NEONATO IPOTONICO

Author

Ferrari, Fabrizio, Lugli, L, Roversi, Mf, Berardi, A, Pugliese, M, Todeschini, A, and Cavalleri, F.

Subjects
neonato ipotonico
Published
2006

46. Apnee neonatali: aspetti neurologici

Author

Ferrari, Fabrizio, Lugli, L, Guerra, Mp, Berardi, A, Roversi, Mf, Ori, L, Todeschini, A, and Cavalleri, F.

Subjects
neonatali, apnee
Published
2006

48. Pattern of care and effectiveness of treatment for glioblastoma patients in the real world: Results from a prospective population-based registry. Could survival differ in a high-volume center?

Author

Brandes, Alba A., primary, Franceschi, Enrico, additional, Ermani, Mario, additional, Tosoni, Alicia, additional, Albani, Fiorenzo, additional, Depenni, Roberta, additional, Faedi, Marina, additional, Pisanello, Anna, additional, Crisi, Girolamo, additional, Urbini, Benedetta, additional, Dazzi, Claudio, additional, Cavanna, Luigi, additional, Mucciarini, Claudia, additional, Pasini, Giuseppe, additional, Bartolini, Stefania, additional, Marucci, Gianluca, additional, Morandi, Luca, additional, Zunarelli, Elena, additional, Cerasoli, Serenella, additional, Gardini, Giorgio, additional, Lanza, Giovanni, additional, Silini, Enrico Maria, additional, Cavuto, Silvio, additional, Baruzzi, Agostino, additional, Baruzzi, A., additional, Albani, F., additional, Calbucci, F., additional, D'Alessandro, R., additional, Michelucci, R., additional, Brandes, A., additional, Eusebi, V., additional, Ceruti, S., additional, Fainardi, E., additional, Tamarozzi, R., additional, Emiliani, E., additional, Cavallo, M., additional, Franceschi, E., additional, Tosoni, A., additional, Fiorica, F., additional, Valentini, A., additional, Depenni, R., additional, Mucciarini, C., additional, Crisi, G., additional, Sasso, E., additional, Biasini, C., additional, Cavanna, L., additional, Guidetti, D., additional, Marcello, N., additional, Pisanello, A., additional, Cremonini, A.M., additional, Guiducci, G., additional, de Pasqua, S., additional, Testoni, S., additional, Agati, R., additional, Ambrosetto, G., additional, Bacci, A., additional, Baldin, E., additional, Baldrati, A., additional, Barbieri, E., additional, Bartolini, S., additional, Bellavista, E., additional, Bisulli, F., additional, Bonora, E., additional, Bunkheila, F., additional, Carelli, V., additional, Crisci, M., additional, Dall'Occa, P., additional, de Biase, D., additional, Ferro, S., additional, Franceschi, C., additional, Frezza, G., additional, Grasso, V., additional, Leonardi, M., additional, Marucci, G., additional, Mazzocchi, V., additional, Morandi, L., additional, Mostacci, B., additional, Palandri, G., additional, Pasini, E., additional, Pastore Trossello, M., additional, Pession, A., additional, Ragazzi, M., additional, Riguzzi, P., additional, Rinaldi, R., additional, Rizzi, S., additional, Romeo, G., additional, Spagnolli, F., additional, Tinuper, P., additional, Trocino, C., additional, Cerasoli, S., additional, Dall'Agata, M., additional, Faedi, M., additional, Frattarelli, M., additional, Gentili, G., additional, Giovannini, A., additional, Iorio, P., additional, Pasquini, U., additional, Galletti, G., additional, Guidi, C., additional, Neri, W., additional, Patuelli, A., additional, Strumia, S., additional, Casmiro, M., additional, Gamboni, A., additional, Rasi, F., additional, Cruciani, G., additional, Cenni, P., additional, Dazzi, C., additional, Guidi, AR., additional, Zumaglini, F., additional, Amadori, A., additional, Pasini, G., additional, Pasquinelli, M., additional, Pasquini, E., additional, Polselli, A., additional, Ravasio, A., additional, Viti, B., additional, Sintini, M., additional, Ariatti, A., additional, Bertolini, F., additional, Bigliardi, G., additional, Carpeggiani, P., additional, Cavalleri, F., additional, Meletti, S., additional, Nichelli, P., additional, Pettorelli, E., additional, Pinna, G., additional, Zunarelli, E., additional, Artioli, F., additional, Bernardini, I., additional, Costa, M., additional, Greco, G., additional, Guerzoni, R., additional, Stucchi, C., additional, Iaccarino, C., additional, Rizzi, R., additional, Zuccoli, G., additional, Api, P., additional, Cartei, F., additional, Fallica, E., additional, Granieri, E., additional, Latini, F., additional, Lelli, G., additional, Monetti, C., additional, Ramponi, V., additional, Saletti, A., additional, Schivalocchi, R., additional, Seraceni, S., additional, Tola, M.R., additional, Urbini, B., additional, Giorgi, C., additional, Montanari, E., additional, Cerasti, D., additional, Crafa, P., additional, Dascola, I., additional, Florindo, I., additional, Mazza, S., additional, Servadei, F., additional, Silini, EM., additional, Torelli, P., additional, Immovilli, P., additional, Morelli, N., additional, and Vanzo, C., additional

Published
2014
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