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1. Role of CDK4 as prognostic biomarker in Soft Tissue Sarcoma and synergistic effect of its inhibition in dedifferentiated liposarcoma sequential treatment

Author

Vanni, Silvia, Miserocchi, Giacomo, Gallo, Graziana, Fausti, Valentina, Gabellone, Sofia, Liverani, Chiara, Spadazzi, Chiara, Cocchi, Claudia, Calabrese, Chiara, De Luca, Giovanni, Bassi, Massimo, Gessaroli, Manlio, Tomasetti, Nicola, Campobassi, Angelo, Pieri, Federica, Ercolani, Giorgio, Cavaliere, Davide, Gurrieri, Lorena, Riva, Nada, Recine, Federica, Ibrahim, Toni, Mercatali, Laura, Jones, Robin, and De Vita, Alessandro

Published
2024
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7. Minimally invasive vs. open segmental resection of the splenic flexure for cancer: a nationwide study of the Italian Society of Surgical Oncology-Colorectal Cancer Network (SICO-CNN)

Author

Degiuli, Maurizio, Ortenzi, Monica, Tomatis, Mariano, Puca, Lucia, Cianflocca, Desiree, Rega, Daniela, Maroli, Annalisa, Elmore, Ugo, Pecchini, Francesca, Milone, Marco, La Mendola, Roberta, Soligo, Erica, Deidda, Simona, Spoletini, Domenico, Cassini, Diletta, Aprile, Alessandra, Mineccia, Michela, Nikaj, Herald, Marchegiani, Francesco, Maiello, Fabio, Bombardini, Cristina, Zuolo, Michele, Carlucci, Michele, Ferraro, Luca, Falato, Armando, Biondi, Alberto, Persiani, Roberto, Marsanich, Patrizia, Fusario, Daniele, Solaini, Leonardo, Pollesel, Sara, Rizzo, Gianluca, Coco, Claudio, Di Leo, Alberto, Cavaliere, Davide, Roviello, Franco, Muratore, Andrea, D’Ugo, Domenico, Bianco, Francesco, Bianchi, Paolo Pietro, De Nardi, Paola, Rigamonti, Marco, Anania, Gabriele, Belluco, Claudio, Polastri, Roberto, Pucciarelli, Salvatore, Gentilli, Sergio, Ferrero, Alessandro, Scabini, Stefano, Baldazzi, Gianandrea, Carlini, Massimo, Restivo, Angelo, Testa, Silvio, Parini, Dario, De Palma, Giovanni Domenico, Piccoli, Micaela, Rosati, Riccardo, Spinelli, Antonino, Delrio, Paolo, Borghi, Felice, Guerrieri, Marco, and Reddavid, Rossella

Published
2023
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11. Correction: Minimally invasive vs. open segmental resection of the splenic flexure for cancer: a nationwide study of the Italian Society of Surgical Oncology-Colorectal Cancer Network (SICO-CNN)

Author

Degiuli, Maurizio, Ortenzi, Monica, Tomatis, Mariano, Puca, Lucia, Cianflocca, Desiree, Rega, Daniela, Maroli, Annalisa, Elmore, Ugo, Pecchini, Francesca, Milone, Marco, La Mendola, Roberta, Soligo, Erica, Deidda, Simona, Spoletini, Domenico, Cassini, Diletta, Aprile, Alessandra, Mineccia, Michela, Nikaj, Herald, Marchegiani, Francesco, Maiello, Fabio, Bombardini, Cristina, Zuolo, Michele, Carlucci, Michele, Ferraro, Luca, Falato, Armando, Biondi, Alberto, Persiani, Roberto, Marsanich, Patrizia, Fusario, Daniele, Solaini, Leonardo, Pollesel, Sara, Rizzo, Gianluca, Coco, Claudio, Di Leo, Alberto, Cavaliere, Davide, Roviello, Franco, Muratore, Andrea, D’Ugo, Domenico, Bianco, Francesco, Bianchi, Paolo Pietro, De Nardi, Paola, Rigamonti, Marco, Anania, Gabriele, Belluco, Claudio, Polastri, Roberto, Pucciarelli, Salvatore, Gentilli, Sergio, Ferrero, Alessandro, Scabini, Stefano, Baldazzi, Gianandrea, Carlini, Massimo, Restivo, Angelo, Testa, Silvio, Parini, Dario, De Palma, Giovanni Domenico, Piccoli, Micaela, Rosati, Riccardo, Spinelli, Antonino, Delrio, Paolo, Borghi, Felice, Guerrieri, Marco, and Reddavid, Rossella

Published
2023
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13. Textbook Outcome in Colorectal Surgery for Cancer: An Italian Version.

Author

Sofia, Silvia, Degiuli, Maurizio, Anania, Gabriele, Baiocchi, Gian Luca, Baldari, Ludovica, Baldazzi, Gianandrea, Bianco, Francesco, Borghi, Felice, Cavaliere, Davide, Coco, Claudio, Coppola, Roberto, D'Ugo, Domenico, Delrio, Paolo, Fumagalli Romario, Uberto, Guerrieri, Mario, Milone, Marco, Morino, Mario, Muratore, Andrea, Navarra, Giuseppe, and Pedrazzani, Corrado

Subjects
PROCTOLOGY, COLORECTAL cancer, ONCOLOGIC surgery, CANCER prognosis, DELPHI method
Abstract

Background/Objectives: The textbook outcome (TO) is a composite tool introduced to uniform surgical units and regulate surgical quality and outcomes. A patient is considered TO only if all predetermined items are met. In colorectal surgery, TO represents a new tool that can achieve important results given the prevalence of colorectal cancers. However, at present, there is a lack of uniformity in the TO's definition. This study utilized the Delphi process to define an Italian version of the TO in colorectal cancer. Methods: The survey consisted of two rounds of online questionnaires submitted to an expert panel in colorectal oncological surgery, renowned academic surgeons, who had attended multiple scientific conferences and who were authors of papers on this specific topic. Five main topics with 26 questions were investigated through an online modified Delphi method. Items with almost 75% agreement achieved consensus. Results: Twenty-eight Italian experts were selected and participated in the two rounds. The Italian version of the textbook outcome in colorectal surgery was defined as the presence of 90-day postoperative survival, negative margins and at least 12 lymph nodes, a minimally invasive approach, ostomy fashioning if preoperatively planned, postoperative complication < Clavien–Dindo 3b, at least 10 ERAS items, no readmission, proper CHT and RT regimens, complete colonoscopy after or before surgery and Tumor Board Evaluation. Conclusions: The textbook outcome in colorectal cancer patients is a quality instrument providing a complete overview of the care of such patients, from diagnosis to treatment. We hereby propose an Italian version of the TO with outcomes chosen by an expert panel. [ABSTRACT FROM AUTHOR]

Published
2024
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14. Clinical and translational implications of immunotherapy in sarcomas.

Author

Recine, Federica, Vanni, Silvia, Bongiovanni, Alberto, Fausti, Valentina, Mercatali, Laura, Miserocchi, Giacomo, Liverani, Chiara, Pieri, Federica, Casadei, Roberto, Cavaliere, Davide, Falbo, Pina Tiziana, Diano, Danila, Ibrahim, Toni, and De Vita, Alessandro

Subjects
SARCOMA, TUMOR-infiltrating immune cells, IMMUNOTHERAPY, TIME complexity, CANCER treatment, SYNOVIOMA
Abstract

Immunotherapy has emerged as promising treatment in sarcomas, but the high variability in terms of histology, clinical behavior and response to treatments determines a particular challenge for its role in these neoplasms. Tumor immune microenvironment (TiME) of sarcomas reflects the heterogeneity of these tumors originating from mesenchymal cells and encompassing more than 100 histologies. Advances in the understanding of the complexity of TiME have led to an improvement of the immunotherapeutic responsiveness in sarcomas, that at first showed disappointing results. The proposed immune-classification of sarcomas based on the interaction between immune cell populations and tumor cells showed to have a prognostic and potential predictive role for immunotherapies. Several studies have explored the clinical impact of immune therapies in the management of these histotypes leading to controversial results. The presence of Tumor Infiltrating Lymphocytes (TIL) seems to correlate with an improvement in the survival of patients and with a higher responsiveness to immunotherapy. In this context, it is important to consider that also immunerelated genes (IRGs) have been demonstrated to have a key role in tumorigenesis and in the building of tumor immune microenvironment. The IRGs landscape in soft tissue and bone sarcomas is characterized by the connection between several tumor-related genes that can assume a potential prognostic and predictive therapeutic role. In this paper, we reviewed the state of art of the principal immune strategies in the management of sarcomas including their clinical and translational relevance. [ABSTRACT FROM AUTHOR]

Published
2024
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15. Skin sea surface temperature schemes in coupled ocean–atmosphere modelling: the impact of chlorophyll-interactive e-folding depth.

Author

de Toma, Vincenzo, Ciani, Daniele, Hesham Essa, Yassmin, Yang, Chunxue, Artale, Vincenzo, Pisano, Andrea, Cavaliere, Davide, Santoleri, Rosalia, and Storto, Andrea

Subjects
OCEAN temperature, ATMOSPHERE, SPRING, ENTHALPY, AUTUMN, SOLAR radiation, OCEAN color
Abstract

In this paper, we explore different prognostic methods to account for skin sea surface temperature diurnal variations in a coupled ocean–atmosphere regional model of the Mediterranean Sea. Our aim is to characterise the sensitivity of the considered methods with respect to the underlying assumption of how the solar radiation shapes the warm layer of the ocean. All existing prognostic methods truncate solar transmission coefficient at a warm-layer reference depth that is constant in space and time; instead, we implement a new scheme where this latter is estimated from a chlorophyll dataset as the e -folding depth of solar transmission, which thus allows it to vary in space and time depending on seawater's transparency conditions. Comparison against satellite data shows that our new scheme, compared to the one already implemented within the ocean model, improves the spatially averaged diurnal signal, especially during winter, and the seasonally averaged one in spring and autumn, while showing a monthly basin-wide averaged bias smaller than 0.1 K year-round. In April, when most of the drifters' measurements are available, the new scheme mitigates the bias during nighttime, keeping it positive but smaller than 0.12 K during the rest of the monthly averaged day. The new scheme implemented within the ocean model improves the old one by about 0.1 K, particularly during June. All the methods considered here showed differences with respect to objectively analysed profiles confined between 0.5 K during winter and 1 K in summer for both the eastern and the western Mediterranean regions, especially over the uppermost 60 m. The new scheme reduces the RMSE on the top 15 m in the central Mediterranean for summertime months compared to the scheme already implemented within the ocean model. Overall, the surface net total heat flux shows that the use of a skin sea surface temperature (SST) parameterisation brings the budget about 1.5 Wm-2 closer to zero on an annual basis, despite all simulations showing an annual net heat loss from the ocean to the atmosphere. Our "chlorophyll-interactive" method proved to be an effective enhancement of existing methods, its strength relying on an improved physical consistency with the solar extinction implemented in the ocean component. [ABSTRACT FROM AUTHOR]

Published
2024
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16. Patient-Reported Outcomes and Return to Intended Oncologic Therapy After Colorectal Enhanced Recovery Pathway: The iCral3 Prospective Study

Author

Catarci, Marco, Ruffo, Giacomo, Viola, Massimo Giuseppe, Ficari, Ferdinando, Delrio, Paolo, Pirozzi, Felice, Borghi, Felice, De Luca, Raffaele, Patriti, Alberto, Garulli, Gianluca, Siquini, Walter, D’Ugo, Stefano, Scabini, Stefano, Caricato, Marco, Pignata, Giusto, Liverani, Andrea, Campagnacci, Roberto, Marini, Pierluigi, Elmore, Ugo, Corcione, Francesco, Santoro, Roberto, Carlini, Massimo, Giuliani, Antonio, Sorrentino, Mario, Ferrari, Giovanni, Baldazzi, Gianandrea, Di Leo, Alberto, Verzelli, Augusto, Sica, Giuseppe, Rausei, Stefano, Cavaliere, Davide, Baiocchi, Gian Luca, Milone, Marco, Ciaccio, Giovanni, Tebala, Giovanni Domenico, Scatizzi, Marco, Boni, Luigi, Mancini, Stefano, Guerrieri, Mario, Persiani, Roberto, Lucchi, Andrea, Parini, Dario, Spinelli, Antonino, Genna, Michele, Bottino, Vincenzo, Coratti, Andrea, Scala, Dario, Muratore, Andrea, Pavanello, Maurizio, Rivolta, Umberto, Piccoli, Micaela, Talarico, Carlo, Carrara, Alessandro, Guadagni, Stefano, Totis, Mauro, Roviello, Franco, Anastasi, Alessandro, Guercioni, Gianluca, Maria Ettorre, Giuseppe, Montuori, Mauro, Mariani, Pierpaolo, de Manzini, Nicolò, Donini, Annibale, Armellino, Mariano Fortunato, Taglietti, Lucio, Anania, Gabriele, Di Cosmo, Mariantonietta, Feo, Carlo Vittorio, Millo, Paolo, Pedrazzani, Corrado, Guerriero, Silvio, Costanzi, Andrea, Vettoretto, Nereo, Marchesi, Federico, Basti, Massimo, Longo, Graziano, Cicetti, Moreno, Ciano, Paolo, Benedetti, Michele, Montemurro, Leonardo Antonio, Mattei, Maria Sole, Belloni, Elena, Bertocchi, Elisa, Masini, Gaia, Altamura, Amedeo, Rubichi, Francesco, Giudici, Francesco, Cianchi, Fabio, Baldini, Gabriele, Pace, Ugo, Bucci, Andrea Fares, Sciuto, Antonio, Cianflocca, Desirée, Migliore, Marco, Simone, Michele, Ricci, Marcella Lodovica, Monari, Francesco, Cardinali, Alessandro, Sartelli, Massimo, Spampinato, Marcello, Aprile, Alessandra, Soriero, Domenico, Capolupo, Gabriella Teresa, Andreuccetti, Jacopo, Canfora, Ilaria, Scarinci, Andrea, Maurizi, Angela, Attinà, Grazia Maria, Maggi, Giulia, Bracale, Umberto, Peltrini, Roberto, Amodio, Pietro, Spoletini, Domenico, Marcellinaro, Rosa, Del Vecchio, Giovanni, Stefanoni, Massimo, Magistro, Carmelo, Cassini, Diletta, Crepaz, Lorenzo, Budassi, Andrea, Sensi, Bruno, Tenconi, Silvia, Solaini, Leonardo, Ercolani, Giorgio, Molfino, Sarah, De Palma, Giovanni Domenico, Locurto, Paolo, Di Cintio, Antonio, Pandolfini, Lorenzo, Falsetto, Alessandro, Cassinotti, Elisa, Sagnotta, Andrea, Ortenzi, Monica, Biondi, Alberto, Martorelli, Giacomo, De Luca, Maurizio, Carrano, Francesco, Maroli, Annalisa, Fior, Francesca, Ferronetti, Antonio, Giuliani, Giuseppe, Benigni, Roberto, Marino, Graziella, Marsanic, Patrizia, Pipitone Federico, Nicoletta Sveva, Di Marco, Carlo, Bertoglio, Camillo Leonardo, Pecchini, Francesca, Greco, Vincenzo, Motter, Michele, Tirone, Giuseppe, Clementi, Marco, Tamini, Nicolò, Piagnerelli, Riccardo, Canonico, Giuseppe, Cicconi, Simone, Colasanti, Marco, Pinotti, Enrico, Carminati, Roberta, Osenda, Edoardo, Graziosi, Luigina, De Martino, Ciro, Ioia, Giovanna, Birindelli, Arianna, Chiozza, Matteo, Zigiotto, Daniele, Pindozzi, Fioralba, Grivon, Manuela, Conti, Cristian, Organetti, Lorenzo, Monteleone, Michela, Botteri, Emanuele, Dalmonte, Giorgio, Frazzini, Diletta, Santoni, Simone, La Gioia, Gabriele, and Giannarelli, Diana

Published
2023
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22. Metaverse and Telementoring: From Surgery to Workshop.

Author

Ammendola, Michele, Vescio, Francesca, Al Ansari, Mohanad, Hila, Jozel, Rizzo, Laura, Romano, Roberto, Marchegiani, Francesco, de'Angelis, Nicola, Piardi, Tullio, Cavaliere, Davide, Frampton, Adam E., Gall, Tamara M. H., Luposella, Maria, Memeo, Riccardo, Navarra, Giuseppe, Curcio, Silvia, and Currò, Giuseppe

Abstract

Background: The Coronavirus 2019 (COVID-19) pandemic has favored the growth of telemedicine systems and in this context the idea of Metaverse was born and developed. A 3D reality in which people can interact with each other through digital reproductions of themselves. Metaverse has already been tested in numerous medical fields due to its ability to combine visual and auditory information with tactile sensations. The purpose of this study is to highlight its potential also in its ability to be used as a telementoring place where the skills and knowledge of surgeons from all over the world can be combined. Material and Methods: The first HPB Surgery Workshop was held at the "Metaverse Surgical Hospital, USA". During the workshop, surgeons located in various parts of the world reported on hepatic, pancreatic and biliary tract surgery and remotely supported the execution of a robotic liver resection. Results: The Metaverse gave the opportunity for surgeons to meet and discuss HPB pathologies and its surgical strategies and for surgeons in training to interface with experts by participating in a moment of advanced training. Conclusion: In the Metaverse, telementoring can be used at very low cost to improve clinical and surgical practice. [ABSTRACT FROM AUTHOR]

Published
2024
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23. The potential role of the extracellular matrix in the activity of trabectedin in UPS and L-sarcoma: evidences from a patient‐derived primary culture case series in tridimensional and zebrafish models

Author

De Vita, Alessandro, Recine, Federica, Miserocchi, Giacomo, Pieri, Federica, Spadazzi, Chiara, Cocchi, Claudia, Vanni, Silvia, Liverani, Chiara, Farnedi, Anna, Fabbri, Francesco, Fausti, Valentina, Casadei, Roberto, Brandolini, Francesca, Ercolani, Giorgio, Cavaliere, Davide, Bongiovanni, Alberto, Riva, Nada, Gurrieri, Lorena, Di Menna, Giandomenico, Calpona, Sebastiano, Debonis, Silvia Angela, Mercatali, Laura, and Ibrahim, Toni

Published
2021
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25. Blow-off in gas turbine combustors

Author

Cavaliere, Davide Egidio

Subjects
620, Gas-turbines--Combustion chambers
Abstract

This thesis describes an experimental investigation of the flame structure close to the extinction and the blow-off events of non-premixed and spray flames stabilized on an axisymmetric bluff body in a confined swirl configuration. The comparison of flames of different canonical types in the same basic aerodynamic field allows insights on the relative blow-off behaviour. The first part of the thesis describes several velocity measurements in non-reacting and reacting flows. The main usefulness of this data is to provide the aerodynamic flow pattern and some discussion on the velocity field and the related recirculation zones. The velocity and turbulence information obtained are particularly useful for providing data, which is crucial for validation of computational models. The second part describes an experimental investigation of non-premixed stable flames very close to the blow-off condition. The measurements included visualisation of the blow-off transient with 5 kHz OH* chemiluminescence, which allowed a quantification of the average duration of the blow-off transient. OH-PLIF images at 5 kHz for flames far from and close to extinction showed that the non-premixed flame intermittently lifts-off the bluff body, with increasing probability as the fuel velocity increases. The flame sheet shows evidence of localised extinctions, which are more pronounced as approaching blow-off. The measurements include blow-off limits and their attempted correlation. It was found that a correlation based on a Damkohler number does a reasonable job at collapsing the dataset. The final part examines the blow-off behaviour of swirling spray flames for two different fuels: n-heptane and n-decane. The measurements include blow-off limits and their att~mpted correlation, visualisation of the blow-off transient with 5 kHz OH* chemiluminescence, and the quantification of the average duration of the blow-off transient. It was found that the average duration of the blow-off event is in order of the tens of ms for both spray flames (10-16 ms). The blow-off event is therefore a relatively slow process for the spray ~ames using n-heptane and decane fuels. This suggests that control measures, such as fast fuel injection, coupled with appropriate detection, such as with chemiluminescence monitoring, may have a reasonable chance of success in keeping the flame alight very close to the blow-off limit. These results, together with those obtained for the non-premixed gaseous case form a wide body of experimental data available for the validation of turbulent flame models. The quantification of some properties during the blow-off transient can assist studies of extinction based on large-eddy simulation that have a promise of capturing combustion transients.

Published
2014
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26. A Systematic Review of Varying Definitions and the Clinical Significance of Fredet’s Fascia in the Era of Complete Mesocolic Excision

Author

Brachini, Gioia, primary, Cirillo, Bruno, additional, Matteucci, Matteo, additional, Cirocchi, Roberto, additional, Tebala, Giovanni Domenico, additional, Cavaliere, Davide, additional, Giacobbi, Lorenza, additional, Papa, Veronica, additional, Solaini, Leonardo, additional, Avenia, Stefano, additional, D’Andrea, Vito, additional, Davies, Justin, additional, Fedeli, Piergiorgio, additional, and De Santis, Elena, additional

Published
2023
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27. Variability of manometric sea level from reanalyses and observation-based products over the Arctic and North Atlantic Oceans and the Mediterranean Sea

Author

Storto, Andrea, primary, Chierici, Giulia, additional, Pfeffer, Julia, additional, Barnoud, Anne, additional, Bourdalle-Badie, Romain, additional, Blazquez, Alejandro, additional, Cavaliere, Davide, additional, Coupry, Benjamin, additional, Drevillon, Marie, additional, Fourest, Sebastien, additional, Larnicol, Gilles, additional, and Yang, Chunxue, additional

Published
2023
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31. Expression levels of circulating miRNAs as biomarkers during multimodal treatment of rectal cancer - TiMiSNAR-mirna: a substudy of the TiMiSNAR Trial (NCT03962088)

Author

Monsellato, Igor, Garibaldi, Elisabetta, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Elmore, Ugo, Delpini, Roberto, Rosati, Riccardo, Perinotti, Roberto, Alongi, Filippo, Bertocchi, Elisa, Gori, Stefania, Ruffo, Giacomo, Pernazza, Graziano, Pulighe, Fabio, De Nisco, Carlo, Morpurgo, Emilio, Contardo, Tania, Mammano, Enzo, Perna, Federico, Menegatti, Benedetta, Coratti, Andrea, Buccianti, Piero, Balestri, Riccardo, Ceccarelli, Cristina, Cavaliere, Davide, Solaini, Leonardo, Ercolani, Giorgio, Traverso, Elena, Fusco, Vittorio, Torri, Valter, and Orecchia, Sara

Published
2020
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34. Abstract 3076: Autologous ECM-composed scaffolds and zebrafish PDXs for individualized theranostics in rare neuroendocrine neoplasms

Author

Calabrese, Chiara, primary, Miserocchi, Giacomo, additional, Vanni, Silvia, additional, De Vita, Alessandro, additional, Bongiovanni, Alberto, additional, Spadazzi, Chiara, additional, Cocchi, Claudia, additional, Ranallo, Nicoletta, additional, Pieri, Federica, additional, Tebaldi, Michela, additional, Foca, Flavia, additional, Ercolani, Giorgio, additional, Cavaliere, Davide, additional, Pacilio, Carlo Alberto, additional, Martinelli, Giovanni, additional, Mercatali, Laura, additional, and Liverani, Chiara, additional

Published
2023
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35. Abstract 5993: Dissecting the role of CDK4 in liposarcoma

Author

Vanni, Silvia, primary, Gallo, Graziana, additional, Fausti, Valentina, additional, Miserocchi, Giacomo, additional, Liverani, Chiara, additional, Spadazzi, Chiara, additional, Cocchi, Claudia, additional, Calabrese, Chiara, additional, De Luca, Giovanni, additional, Bassi, Massimo, additional, Gessaroli, Manlio, additional, Campobassi, Angelo, additional, Pieri, Federica, additional, Ercolani, Giorgio, additional, Cavaliere, Davide, additional, Gurrieri, Lorena, additional, Riva, Nada, additional, Martinelli, Giovanni, additional, Mercatali, Laura, additional, and De Vita, Alessandro, additional

Published
2023
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36. Segmental Colonic Resection Is a Safe and Effective Treatment Option for Colon Cancer of the Splenic Flexure: A Nationwide Retrospective Study of the Italian Society of Surgical Oncology–Colorectal Cancer Network Collaborative Group

Author

Degiuli, Maurizio, Reddavid, Rossella, Ricceri, Fulvio, Di Candido, Francesca, Ortenzi, Monica, Elmore, Ugo, Belluco, Claudio, Rosati, Riccardo, Guerrieri, Marco, Spinelli, Antonino, De Nardi, Paola, Cianflocca, Desiree, Borghi, Felice, Rega, Daniela, Delrio, Paolo, Milone, Marco, Domenico De Palma, Giovanni, Restivo, Angelo, Deidda, Simona, Testa, Silvio, Scansetti, Mario, Baldazzi, Gianandrea, Cassini, Diletta, Scabini, Stefano, Sparavigna, Marco, Gentilli, Sergio, Monni, Manuela, Marchegiani, Francesco, Zuin, Matteo, Sorisio, Vincenzo, Castelano, Edoardo, Polastri, Roberto, Maiello, Fabio, Piccoli, Micaela, Pecchini, Francesca, Ferrero, Alessandro, Mineccia, Michela, Parini, Dario, D’Ugo, Domenico, Biondi, Alberto, Cavaliere, Davide, Solaini, Leonardo, Carlini, Massimo, Spoletini, Domenico, Olivieri, Matteo, Anania, Gabriele, Bombardini, Cristina, Coco, Claudio, Rizzo, Gianluca, Rigamonti, Marco, Zuolo, Michele, Belli, Andrea, Bianco, Francesco, Roviello, Franco, Pollesel, Sara, Di Leo, Alberto, Carafa, Francesco, Paolo Bianchi, Pietro, Giuliani, Giuseppe, Muratore, Andrea, and Marsanic, Patrizia

Published
2020
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38. Correction to: Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: a multicenter randomized controlled parallel group trial (TiMiSNAR)

Author

Monsellato, Igor, Alongi, Filippo, Bertocchi, Elisa, Gori, Stefania, Ruffo, Giacomo, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Pernazza, Graziano, Pulighe, Fabio, De Nisco, Carlo, Perinotti, Roberto, Morpurgo, Emilio, Contardo, Tania, Mammano, Enzo, Elmore, Ugo, Delpini, Roberto, Rosati, Riccardo, Perna, Federico, Coratti, Andrea, Menegatti, Benedetta, Gentilli, Sergio, Baroffio, Paolo, Buccianti, Piero, Balestri, Riccardo, Ceccarelli, Cristina, Torri, Valter, Cavaliere, Davide, Solaini, Leonardo, Ercolani, Giorgio, Traverso, Elena, Fusco, Vittorio, Rossi, Maura, Priora, Fabio, Numico, G., Franzone, Paola, and Orecchia, Sara

Published
2020
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39. Standard (8 weeks) vs long (12 weeks) timing to minimally-invasive surgery after NeoAdjuvant Chemoradiotherapy for rectal cancer: a multicenter randomized controlled parallel group trial (TiMiSNAR)

Author

Monsellato, Igor, Alongi, Filippo, Bertocchi, Elisa, Gori, Stefania, Ruffo, Giacomo, Cassinotti, Elisa, Baldarti, Ludovica, Boni, Luigi, Pernazza, Graziano, Pulighe, Fabio, De Nisco, Carlo, Perinotti, Roberto, Morpurgo, Emilio, Contardo, Tania, Mammano, Enzo, Elmore, Ugo, Delpini, Roberto, Rosati, Riccardo, Perna, Federico, Coratti, Andrea, Menegatti, Benedetta, Gentilli, Sergio, Baroffio, Paolo, Buccianti, Piero, Balestri, Riccardo, Ceccarelli, Cristina, Torri, Valter, Cavaliere, Davide, Solaini, Leonardo, Ercolani, Giorgio, Traverso, Elena, Fusco, Vittorio, Rossi, Maura, Priora, Fabio, Numico, G., Franzone, Paola, and Orecchia, Sara

Published
2019
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40. Colorectal Cancer Stage at Diagnosis Before vs During the COVID-19 Pandemic in Italy

Author

Rottoli, Matteo, Gori, Alice, Pellino, Gianluca, Flacco, Maria Elena, Martellucci, Cecilia, Spinelli, Antonino, Poggioli, Gilberto, Romano, Angela, Belvedere, Angela, Lanci Lanci, Antonio, Parlanti, Daniele, Vago, Gabriele, Pezzuto, Paola, Canavese, Anna, Dajti, Gerti, Cardelli, Stefano, Catalioto, Caterina, Russo, Iris S, Violante, Tommaso, Morezzi, Daniele, Maurino, Ludovica, Filippone, Eleonora, Cuicchi, Dajana, Bernante, Paolo, Jovine, Elio, Lombardi, Raffaele, Masetti, Michele, Cipressi, Chiara, Offi, Maria F, Larotonda, Cristina, Puglisi, Silvana B, Barbosa, Augusto, Vaiana, Roberto, Bianchi, Paolo M, Tonti, Carlo, Codignola, Claudio, Zorcolo, Luigi, Restivo, Angelo, Deidda, Simona, Marchetti, Marcello E, Ippolito, Luca, Spolverato, Gaya, Pucciarelli, Salvatore, Marchegiani, Francesco, Ghio, Giacomo, Zagolin, Gaya, Glavas, Dajana, Tomassi, Monica, Rosati, Riccardo, Elmore, Ugo, Gozzini, Lorenzo, Calef, Riccardo, Puccetti, Francesco, Cossu, Andrea, Vignali, Andrea, Morino, Mario, Allaix, Marco E, Cannata, Gaspare, Lombardi, Erica, Ammirati, Carlo A, Piceni, Chiara, Buccianti, Piero, Balestri, Riccardo, Puccini, Marco, Pezzati, Daniele, d'Ischia, Roberto, Asta, Vito F, Sargenti, Benedetta, Taddei, Giacomo, Bonari, Federica, Boni, Giulia, Ferrero, Alessandro, Mineccia, Michela, Gonella, Federica, Palisi, Marco, Danese, Francesco, Cherubini, Valeria, Perotti, Serena, Carvello, Michele, Carbone, Fabio, Luberto, Antonio, Calafiore, Eleonora, De Lucia, Francesca, Sacchi, Matteo, Sasia, Diego, Giuffrida, Maria C, Ballauri, Edoardo, Cardile, Mathieu, Armentano, Serena, Beltrami, Elsa, Preve, Gabriele, Vercellone, Barbara, Mozzon, Marta, Folliero, Cristina, Lirusso, Chiara, Vecchiato, Massimo, Ziccarelli, Antonio, Gattesco, Davide, Moretti, Luisa, Crestale, Sara, Banchini, Filippo, Capelli, Patrizio, Romboli, Andrea, Palmieri, Gerardo, Conti, Luigi, Rizzi, Nicholas, Bonfili, Deborah, de Manzini, Nicolò, Germani, Paola, Osenda, Edoardo, Cortinovis, Sara, Giunta, Carlotta, Fracon, Stefano, Abdallah, Hussein, Bogoni, Selene, Portolani, Nazario, Nascimbeni, Riccardo, Molfino, Sarah, Tiberio, Guido A M, Garosio, Ilenia, Lamperti, Giulia, Rigosa, Diego, Ercolani, Giorgio, Solaini, Leonardo, Cavaliere, Davide, Avanzolini, Andrea, D'Acapito, Fabrizio, Chiarella, Leonardo L, Di Pietrantonio, Daniela, Annunziata, Domenico, Piccolo, Roberta, Sorrentino, Mario, Pansini, Mauro, Cojutti, Alessandro, Graziano, Michele, Callegari, Francesco, Balzarotti, Laura, Dameno, Vitale R, Cattaneo, Antonio, Santolamazza, Giuliano, Altieri, Caterina, Magarini, Riccardo, Pietrabissa, Andrea, Dominioni, Tommaso, Pugliese, Luigi, Peri, Andrea, Botti, Marta, Salvetti, Francesco, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Messina, Valentina, D'Abrosca, Vera, Cianci, Pasquale, Tumolo, Rocco, Gattulli, Domenico, Restini, Enrico, Minafra, Marina, Sederino, Maria G, Bottalico, Bernardino, Pilati, Pierluigi, Franzato, Boris, Mattara, Genny, De Simoni, Ottavia, Barina, Andrea, Tonello, Marco, Muratore, Andrea, Calabrò, Marcello, Federico Pipitone, Nicoletta S, Cuzzola, Bruno, Herranz van Nood, Elena, Passuello, Nicola, Frasson, Alvise, Mammano, Enzo, Faccio, Luca, Vittadello, Fabrizio, Bressan, Alice, Sarzo, Giacomo, Tamini, Nicolò, Oldani, Massimo, Cigagna, Luca, Carissimi, Francesca, De Carlo, Giulia, Baccalini, Edoardo, Nespoli, Luca, Giordano, Alessio, Cantafio, Stefano, Grifoni, Lucrezia, Matani, Davide, Livi, Serena, Delogu, Daniele, Scognamillo, Fabrizio, Marrosu, Antonio, Guerrini, Luca, Ugolini, Giampaolo, Ghignone, Federico, Frascaroli, Giacomo, Albertini, Nicola, Zattoni, Davide, Taffurelli, Giovanni, Montroni, Isacco, Colombo, Francesco, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Bonomi, Alessandro, Pezzoli, Isabella, Cammarata, Francesco, Goletti, Orlando, Molteni, Mattia, Assisi, Alberto, Quartierini, Giorgio, Da Lio, Corrado, Verdi, Daunia, Mondi, Isabella, Peluso, Claudia, Macchi, Lorenzo, Tanzanu, Marta, Zanzi, Federico, Pellegrini, Sara, Andreuccetti, Jacopo, D'Alessio, Rossella, Pignata, Giusto, De Capua, Michele, Canfora, Ilaria, Ottaviani, Luca, Lepiane, Pasquale, Balla, Andrea, De Carlo, Antonio, Saraceno, Federica, Scaramuzzo, Rosa, Guida, Anna, Aguzzi, Daniele, Bellora, Paolo, Gentilli, Sergio, Monni, Manuela, Nikaj, Herald, Cillara, Nicola, Cannavera, Alessandro, Deserra, Antonello, Margiani, Carla, Cabula, Roberta, Dettori, Manuela, Gramignano, Giulia, Lezoche, Giovanni, Ortenzi, Monica, Orlandoni, Elena S, Curzi, Federica, Vitali, Francesca, Capomagi, Perla, Palmieri, Miriam, Giuffrida, Mario, Del Rio, Paolo, Bonati, Elena, Loderer, Tommaso, Cozzani, Federico, Rossini, Matteo, Agnesi, Stefano, Capolupo, Gabriella T, Caricato, Marco, Carannante, Filippo, Mascianà, Gianluca, Marrelli, Martina, Miacci, Valentina, Lauricella, Sara, Tonini, Valeria, Cervellera, Maurizio, Pisconti, Salvatore, Lozito, Concetta, Shahu, Juliana, Mongelli, Claudia, Morelli, Giulia, Sartarelli, Lodovico, Sica, Giuseppe S, Siragusa, Leandro, Bagaglini, Giulia, Sensi, Bruno, Guida, Andrea M, Franceschilli, Marzia, Vinci, Danilo, Taddei, Antonio, Risaliti, Matteo, Bartolini, Ilenia, Ringressi, Maria N, Tirloni, Luca, Laface, Letizia, Abate, Emmanuele, Casati, Massimiliano, Gobbi, Pietro, Opocher, Enrico, Mariani, Nicolò M, Pisani Ceretti, Andrea, Giovenzana, Marco, Giuliani, Beatrice, Sironi, Martina, Grossi, Ugo, Zanus, Giacomo, Aniello Santoro, Giulio, Brizzolari, Marco, De Leo, Eugenio, Novello, Simone, Aquilino, Krizia, Milardi, Francesco, Olmi, Stefano, Uccelli, Matteo, Bonaldi, Marta, Cesana, Giovanni C, Bindi, Marco, Galleano, Raffaele, Langone, Antonio, Botto, Massimiliano, Franceschi, Angelo, Gambino, Elena, Ronconi, Maurizio, Casiraghi, Silvia, Casole, Giovanni, Ciulla, Salvatore L, Terrosu, Giovanni, Calandra, Sergio, Scarpa, Edoardo, Cherchi, Vittorio, Calini, Giacomo, Martinuzzo, Lisa, Clocchiatti, Lucrezia, Muschitiello, Davide, Romanzi, Andrea, Vignati, Barbara, Vannelli, Alberto, Scolaro, Roberta, Milanesi, Maria, Rossi, Fabrizio, Canonico, Giuseppe, Anastasi, Alessandro, Nelli, Tommaso, Barlettai, Marco, Fratarcangeli, Riccardo, Di Martino, Carmela, Damigella, Andrea, Adinolfi, Elvira, Birindelli, Arianna, Taglietti, Lucio, Dester, Sara E, Fleres, Francesco, Cucinotta, Eugenio, Viscosi, Francesca, Biondo Santino, Antonio, Badessi, Giorgio, Catarsini, Nivia, Mazzeo, Carmelo, Rega, Daniela, Delrio, Paolo, Cervone, Carmela, Aversano, Alessia, De Franciscis, Silvia, Di Marzo, Massimiliano, Marra, Bruno, Pace, Ugo, Amato, Antonio, Batistotti, Paola, Mina, Elisa, Serventi, Alberto, Lapolla, Pierfrancesco, Mingoli, Andrea, Sapienza, Paolo, Brachini, Gioia, Cirillo, Bruno, Fiori, Enrico, Crocetti, Daniele, Clementi, Ilaria, Martines, Gennaro, Picciariello, Arcangelo, Tomasicchio, Giovanni, Dibra, Rigers, Trigiante, Giuseppe, Rinaldi, Marcella, Lantone, Giuliano, Porcu, Alberto, Perra, Teresa, Scanu, Antonio M, Feo, Claudio F, Fancellu, Alessandro, Cossu, Maria L, Ginesu, Giorgio C, Patriti, Alberto, Coletta, Diego, Petrelli, Filippo, Greco, Paola A, Spadoni, Claudia, Cassiani, Giovanna, Bianchini, Federica, Arganini, Marco, Bianchini, Matteo, Perotti, Bruno, Palmeri, Matteo, Scabini, Stefano, Deiana, Selene, Carganico, Giacomo, Pertile, Davide, Soriero, Domenico, Fioravanti, Emanuela, Sperotto, Beatrice, Nardo, Bruno, Paglione, Daniele, Crocco, Veronica, Doni, Marco, Osso, Mariasara, Perri, Roberto, Sampietro, Gianluca M, Corbellini, Carlo, Lorusso, Leonardo, Manzo, Carlo A, Cigognini, Maria, Baldi, Caterina, Palomba, Giuseppe, Aprea, Giovanni, Capuano, Marianna, Basile, Raffaele, Tutino, Roberta, Massani, Marco, Marinelli, Laura, Canitano, Nicola, Pilia, Tiziana, Podda, Mauro, Pisanu, Adolfo, Murzi, Valentina, Incani, Silvia, Frongia, Federica, Esposito, Giuseppe, Luglio, Gaetano, Tropeano, Francesca P, Pagano, Gianluca, Spina, Eduardo, De Simone, Giuseppe, Cricrì, Michele, Catena, Fausto, Vallicelli, Carlo, Zanini, Nicola, Ronconi, Diana, Favi, Francesco, Mazzucchelli, Carlo, Convertini, Girolamo, Vincenti, Leonardo, Andriola, Valeria, Bizzoca, Cinzia, Feo, Carlo V, Fabbri, Nicolò, Fazzin, Marta, Pesce, Antonio, Gennari, Silvia, Torchiaro, Marco, Severi, Silvia, Frontali, Alice, Bracchetti, Greta, Granieri, Stefano, Cotsoglou, Christian, Carlini, Massimo, Lisi, Giorgio, Spoletini, Domenico, Mastrangeli, Maria R, Campanelli, Michela, Manigrasso, Michele, Milone, Marco, De Palma, Giovanni D, Vertaldi, Sara, Chini, Alessia, Maione, Francesco, Marello, Alessandra, Selvaggi, Francesco, Sciaudone, Guido, Selvaggi, Lucio, Menegon Tasselli, Francesco, Fuschillo, Giacomo, Oddis, Lidia, Grande, Simona, Grande, Michele, Ascanelli, Simona, Chimisso, Laura, Aisoni, Filippo, Rossin, Eleonora, Pepe, Francesco, Marchetti, Francesco, Picardi, Biagio, Rossi, Stefano, Rossi Del Monte, Simone, Picarelli, Matteo, Muttillo, Irnerio A, Ratto, Carlo, Marra, Angelo A, Parello, Angelo, Litta, Francesco, Campennì, Paola, De Simone, Veronica, Pata, Francesco, Riboni, Cristiana, Rausa, Emanuele, Celentano, Valerio, Institut Català de la Salut, [Rottoli M, Gori A, Pellino G] Surgery of the Alimentary Tract, IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy. Surgery of the Alimentary Tract, IRCCS Azienda Ospedaliero–Universitaria di Bologna, Bologna, Italy. [Pellino G] Department of Advanced Medical and Surgical Sciences, Università degli Studi della Campania Luigi Vanvitelli, Naples, Italy. Unitat de Cirurgia de Còlon i Recte, Vall d’Hebron Hospital Universitari, Barcelona, Spain. [Flacco ME, Martellucci C] Department of Environmental and Preventive Sciences, University of Ferrara, Ferrara, Italy. [Spinelli A] Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy. Colorectal Surgery, IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy, Vall d'Hebron Barcelona Hospital Campus, Rottoli, Matteo, Gori, Alice, Pellino, Gianluca, Flacco, Maria Elena, Martellucci, Cecilia, Spinelli, Antonino, Poggioli, Gilberto, Romano, Angela, Belvedere, Angela, Lanci Lanci, Antonio, Parlanti, Daniele, Vago, Gabriele, Pezzuto, Paola, Canavese, Anna, Dajti, Gerti, Cardelli, Stefano, Catalioto, Caterina, Russo, Iris S, Violante, Tommaso, Morezzi, Daniele, Maurino, Ludovica, Filippone, Eleonora, Cuicchi, Dajana, Bernante, Paolo, Jovine, Elio, Lombardi, Raffaele, Masetti, Michele, Cipressi, Chiara, Offi, Maria F, Larotonda, Cristina, Puglisi, Silvana B, Barbosa, Augusto, Vaiana, Roberto, Bianchi, Paolo M, Tonti, Carlo, Codignola, Claudio, Zorcolo, Luigi, Restivo, Angelo, Deidda, Simona, Marchetti, Marcello E, Ippolito, Luca, Spolverato, Gaya, Pucciarelli, Salvatore, Marchegiani, Francesco, Ghio, Giacomo, Zagolin, Gaya, Glavas, Dajana, Tomassi, Monica, Rosati, Riccardo, Elmore, Ugo, Gozzini, Lorenzo, Calef, Riccardo, Puccetti, Francesco, Cossu, Andrea, Vignali, Andrea, Morino, Mario, Allaix, Marco E, Cannata, Gaspare, Lombardi, Erica, Ammirati, Carlo A, Piceni, Chiara, Buccianti, Piero, Balestri, Riccardo, Puccini, Marco, Pezzati, Daniele, d'Ischia, Roberto, Asta, Vito F, Sargenti, Benedetta, Taddei, Giacomo, Bonari, Federica, Boni, Giulia, Ferrero, Alessandro, Mineccia, Michela, Gonella, Federica, Palisi, Marco, Danese, Francesco, Cherubini, Valeria, Perotti, Serena, Carvello, Michele, Carbone, Fabio, Luberto, Antonio, Calafiore, Eleonora, De Lucia, Francesca, Sacchi, Matteo, Sasia, Diego, Giuffrida, Maria C, Ballauri, Edoardo, Cardile, Mathieu, Armentano, Serena, Beltrami, Elsa, Preve, Gabriele, Vercellone, Barbara, Mozzon, Marta, Folliero, Cristina, Lirusso, Chiara, Vecchiato, Massimo, Ziccarelli, Antonio, Gattesco, Davide, Moretti, Luisa, Crestale, Sara, Banchini, Filippo, Capelli, Patrizio, Romboli, Andrea, Palmieri, Gerardo, Conti, Luigi, Rizzi, Nichola, Bonfili, Deborah, de Manzini, Nicolò, Germani, Paola, Osenda, Edoardo, Cortinovis, Sara, Giunta, Carlotta, Fracon, Stefano, Abdallah, Hussein, Bogoni, Selene, Portolani, Nazario, Nascimbeni, Riccardo, Molfino, Sarah, Tiberio, Guido A M, Garosio, Ilenia, Lamperti, Giulia, Rigosa, Diego, Ercolani, Giorgio, Solaini, Leonardo, Cavaliere, Davide, Avanzolini, Andrea, D'Acapito, Fabrizio, Chiarella, Leonardo L, Di Pietrantonio, Daniela, Annunziata, Domenico, Piccolo, Roberta, Sorrentino, Mario, Pansini, Mauro, Cojutti, Alessandro, Graziano, Michele, Callegari, Francesco, Balzarotti, Laura, Dameno, Vitale R, Cattaneo, Antonio, Santolamazza, Giuliano, Altieri, Caterina, Magarini, Riccardo, Pietrabissa, Andrea, Dominioni, Tommaso, Pugliese, Luigi, Peri, Andrea, Botti, Marta, Salvetti, Francesco, Cassinotti, Elisa, Baldari, Ludovica, Boni, Luigi, Messina, Valentina, D'Abrosca, Vera, Cianci, Pasquale, Tumolo, Rocco, Gattulli, Domenico, Restini, Enrico, Minafra, Marina, Sederino, Maria G, Bottalico, Bernardino, Pilati, Pierluigi, Franzato, Bori, Mattara, Genny, De Simoni, Ottavia, Barina, Andrea, Tonello, Marco, Muratore, Andrea, Calabrò, Marcello, Federico Pipitone, Nicoletta S, Cuzzola, Bruno, Herranz van Nood, Elena, Passuello, Nicola, Frasson, Alvise, Mammano, Enzo, Faccio, Luca, Vittadello, Fabrizio, Bressan, Alice, Sarzo, Giacomo, Tamini, Nicolò, Oldani, Massimo, Cigagna, Luca, Carissimi, Francesca, De Carlo, Giulia, Baccalini, Edoardo, Nespoli, Luca, Giordano, Alessio, Cantafio, Stefano, Grifoni, Lucrezia, Matani, Davide, Livi, Serena, Delogu, Daniele, Scognamillo, Fabrizio, Marrosu, Antonio, Guerrini, Luca, Ugolini, Giampaolo, Ghignone, Federico, Frascaroli, Giacomo, Albertini, Nicola, Zattoni, Davide, Taffurelli, Giovanni, Montroni, Isacco, Colombo, Francesco, Danelli, Piergiorgio, Bondurri, Andrea, Maffioli, Anna, Bonomi, Alessandro, Pezzoli, Isabella, Cammarata, Francesco, Goletti, Orlando, Molteni, Mattia, Assisi, Alberto, Quartierini, Giorgio, Da Lio, Corrado, Verdi, Daunia, Mondi, Isabella, Peluso, Claudia, Macchi, Lorenzo, Tanzanu, Marta, Zanzi, Federico, Pellegrini, Sara, Andreuccetti, Jacopo, D'Alessio, Rossella, Pignata, Giusto, De Capua, Michele, Canfora, Ilaria, Ottaviani, Luca, Lepiane, Pasquale, Balla, Andrea, De Carlo, Antonio, Saraceno, Federica, Scaramuzzo, Rosa, Guida, Anna, Aguzzi, Daniele, Bellora, Paolo, Gentilli, Sergio, Monni, Manuela, Nikaj, Herald, Cillara, Nicola, Cannavera, Alessandro, Deserra, Antonello, Margiani, Carla, Cabula, Roberta, Dettori, Manuela, Gramignano, Giulia, Lezoche, Giovanni, Ortenzi, Monica, Orlandoni, Elena S, Curzi, Federica, Vitali, Francesca, Capomagi, Perla, Palmieri, Miriam, Giuffrida, Mario, Del Rio, Paolo, Bonati, Elena, Loderer, Tommaso, Cozzani, Federico, Rossini, Matteo, Agnesi, Stefano, Capolupo, Gabriella T, Caricato, Marco, Carannante, Filippo, Mascianà, Gianluca, Marrelli, Martina, Miacci, Valentina, Lauricella, Sara, Tonini, Valeria, Cervellera, Maurizio, Pisconti, Salvatore, Lozito, Concetta, Shahu, Juliana, Mongelli, Claudia, Morelli, Giulia, Sartarelli, Lodovico, Sica, Giuseppe S, Siragusa, Leandro, Bagaglini, Giulia, Sensi, Bruno, Guida, Andrea M, Franceschilli, Marzia, Vinci, Danilo, Taddei, Antonio, Risaliti, Matteo, Bartolini, Ilenia, Ringressi, Maria N, Tirloni, Luca, Laface, Letizia, Abate, Emmanuele, Casati, Massimiliano, Gobbi, Pietro, Opocher, Enrico, Mariani, Nicolò M, Pisani Ceretti, Andrea, Giovenzana, Marco, Giuliani, Beatrice, Sironi, Martina, Grossi, Ugo, Zanus, Giacomo, Aniello Santoro, Giulio, Brizzolari, Marco, De Leo, Eugenio, Novello, Simone, Aquilino, Krizia, Milardi, Francesco, Olmi, Stefano, Uccelli, Matteo, Bonaldi, Marta, Cesana, Giovanni C, Bindi, Marco, Galleano, Raffaele, Langone, Antonio, Botto, Massimiliano, Franceschi, Angelo, Gambino, Elena, Ronconi, Maurizio, Casiraghi, Silvia, Casole, Giovanni, Ciulla, Salvatore L, Terrosu, Giovanni, Calandra, Sergio, Scarpa, Edoardo, Cherchi, Vittorio, Calini, Giacomo, Martinuzzo, Lisa, Clocchiatti, Lucrezia, Muschitiello, Davide, Romanzi, Andrea, Vignati, Barbara, Vannelli, Alberto, Scolaro, Roberta, Milanesi, Maria, Rossi, Fabrizio, Canonico, Giuseppe, Anastasi, Alessandro, Nelli, Tommaso, Barlettai, Marco, Fratarcangeli, Riccardo, Di Martino, Carmela, Damigella, Andrea, Adinolfi, Elvira, Birindelli, Arianna, Taglietti, Lucio, Dester, Sara E, Fleres, Francesco, Cucinotta, Eugenio, Viscosi, Francesca, Biondo Santino, Antonio, Badessi, Giorgio, Catarsini, Nivia, Mazzeo, Carmelo, Rega, Daniela, Delrio, Paolo, Cervone, Carmela, Aversano, Alessia, De Franciscis, Silvia, Di Marzo, Massimiliano, Marra, Bruno, Pace, Ugo, Amato, Antonio, Batistotti, Paola, Mina, Elisa, Serventi, Alberto, Lapolla, Pierfrancesco, Mingoli, Andrea, Sapienza, Paolo, Brachini, Gioia, Cirillo, Bruno, Fiori, Enrico, Crocetti, Daniele, Clementi, Ilaria, Martines, Gennaro, Picciariello, Arcangelo, Tomasicchio, Giovanni, Dibra, Riger, Trigiante, Giuseppe, Rinaldi, Marcella, Lantone, Giuliano, Porcu, Alberto, Perra, Teresa, Scanu, Antonio M, Feo, Claudio F, Fancellu, Alessandro, Cossu, Maria L, Ginesu, Giorgio C, Patriti, Alberto, Coletta, Diego, Petrelli, Filippo, Greco, Paola A, Spadoni, Claudia, Cassiani, Giovanna, Bianchini, Federica, Arganini, Marco, Bianchini, Matteo, Perotti, Bruno, Palmeri, Matteo, Scabini, Stefano, Deiana, Selene, Carganico, Giacomo, Pertile, Davide, Soriero, Domenico, Fioravanti, Emanuela, Sperotto, Beatrice, Nardo, Bruno, Paglione, Daniele, Crocco, Veronica, Doni, Marco, Osso, Mariasara, Perri, Roberto, Sampietro, Gianluca M, Corbellini, Carlo, Lorusso, Leonardo, Manzo, Carlo A, Cigognini, Maria, Baldi, Caterina, Palomba, Giuseppe, Aprea, Giovanni, Capuano, Marianna, Basile, Raffaele, Tutino, Roberta, Massani, Marco, Marinelli, Laura, Canitano, Nicola, Pilia, Tiziana, Podda, Mauro, Pisanu, Adolfo, Murzi, Valentina, Incani, Silvia, Frongia, Federica, Esposito, Giuseppe, Luglio, Gaetano, Tropeano, Francesca P, Pagano, Gianluca, Spina, Eduardo, De Simone, Giuseppe, Cricrì, Michele, Catena, Fausto, Vallicelli, Carlo, Zanini, Nicola, Ronconi, Diana, Favi, Francesco, Mazzucchelli, Carlo, Convertini, Girolamo, Vincenti, Leonardo, Andriola, Valeria, Bizzoca, Cinzia, Feo, Carlo V, Fabbri, Nicolò, Fazzin, Marta, Pesce, Antonio, Gennari, Silvia, Torchiaro, Marco, Severi, Silvia, Frontali, Alice, Bracchetti, Greta, Granieri, Stefano, Cotsoglou, Christian, Carlini, Massimo, Lisi, Giorgio, Spoletini, Domenico, Mastrangeli, Maria R, Campanelli, Michela, Manigrasso, Michele, Milone, Marco, De Palma, Giovanni D, Vertaldi, Sara, Chini, Alessia, Maione, Francesco, Marello, Alessandra, Selvaggi, Francesco, Sciaudone, Guido, Selvaggi, Lucio, Menegon Tasselli, Francesco, Fuschillo, Giacomo, Oddis, Lidia, Grande, Simona, Grande, Michele, Ascanelli, Simona, Chimisso, Laura, Aisoni, Filippo, Rossin, Eleonora, Pepe, Francesco, Marchetti, Francesco, Picardi, Biagio, Rossi, Stefano, Rossi Del Monte, Simone, Picarelli, Matteo, Muttillo, Irnerio A, Ratto, Carlo, Marra, Angelo A, Parello, Angelo, Litta, Francesco, Campennì, Paola, De Simone, Veronica, Pata, Francesco, Riboni, Cristiana, Rausa, Emanuele, and Celentano, Valerio

Subjects
Adult, Male, Settore MED/18 - CHIRURGIA GENERALE, Otros calificadores::/diagnóstico [Otros calificadores], Hospitals, Community, colorectal cancer, Community, advanced stage, COVID-19 (Malaltia), Cohort Studies, Neoplasms::Neoplasms by Site::Digestive System Neoplasms::Gastrointestinal Neoplasms::Intestinal Neoplasms::Colorectal Neoplasms [DISEASES], Retrospective Studie, Other subheadings::/diagnosis [Other subheadings], virosis::infecciones por virus ARN::infecciones por Nidovirales::infecciones por Coronaviridae::infecciones por Coronavirus [ENFERMEDADES], Humans, Pandemics, Aged, Retrospective Studies, Pandemic, SARS-CoV-2, COVID-19, Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections [DISEASES], General Medicine, neoplasias::neoplasias por localización::neoplasias del sistema digestivo::neoplasias gastrointestinales::neoplasias intestinales::neoplasias colorrectales [ENFERMEDADES], Hospitals, Recte - Càncer - Diagnòstic, Settore MED/18, Italy, Còlon - Càncer - Diagnòstic, Cohort Studie, Colorectal Neoplasms, Human
Abstract

ImportanceDelays in screening programs and the reluctance of patients to seek medical attention because of the outbreak of SARS-CoV-2 could be associated with the risk of more advanced colorectal cancers at diagnosis.ObjectiveTo evaluate whether the SARS-CoV-2 pandemic was associated with more advanced oncologic stage and change in clinical presentation for patients with colorectal cancer.Design, Setting, and ParticipantsThis retrospective, multicenter cohort study included all 17 938 adult patients who underwent surgery for colorectal cancer from March 1, 2020, to December 31, 2021 (pandemic period), and from January 1, 2018, to February 29, 2020 (prepandemic period), in 81 participating centers in Italy, including tertiary centers and community hospitals. Follow-up was 30 days from surgery.ExposuresAny type of surgical procedure for colorectal cancer, including explorative surgery, palliative procedures, and atypical or segmental resections.Main Outcomes and MeasuresThe primary outcome was advanced stage of colorectal cancer at diagnosis. Secondary outcomes were distant metastasis, T4 stage, aggressive biology (defined as cancer with at least 1 of the following characteristics: signet ring cells, mucinous tumor, budding, lymphovascular invasion, perineural invasion, and lymphangitis), stenotic lesion, emergency surgery, and palliative surgery. The independent association between the pandemic period and the outcomes was assessed using multivariate random-effects logistic regression, with hospital as the cluster variable.ResultsA total of 17 938 patients (10 007 men [55.8%]; mean [SD] age, 70.6 [12.2] years) underwent surgery for colorectal cancer: 7796 (43.5%) during the pandemic period and 10 142 (56.5%) during the prepandemic period. Logistic regression indicated that the pandemic period was significantly associated with an increased rate of advanced-stage colorectal cancer (odds ratio [OR], 1.07; 95% CI, 1.01-1.13; P = .03), aggressive biology (OR, 1.32; 95% CI, 1.15-1.53; P P = .03).Conclusions and RelevanceThis cohort study suggests a significant association between the SARS-CoV-2 pandemic and the risk of a more advanced oncologic stage at diagnosis among patients undergoing surgery for colorectal cancer and might indicate a potential reduction of survival for these patients.

Published
2022

41. Organizational Problems, Costs, and Data Collection

Author

Vallicelli, Carlo, Sibio, Simone, Cardi, Maurizio, Cavaliere, Davide, Verdecchia, Giorgio Maria, Di Giorgio, Angelo, editor, Pinto, Enrico, editor, Sammartino, Paolo, Cooperation partner, Roviello, Franco, Cooperation partner, and De Toma, Giorgio

Published
2015
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43. Systemic Inflammatory Indices in Second-Line Soft Tissue Sarcoma Patients: Focus on Lymphocyte/Monocyte Ratio and Trabectedin

Author

Fausti, Valentina, primary, De Vita, Alessandro, additional, Vanni, Silvia, additional, Ghini, Virginia, additional, Gurrieri, Lorena, additional, Riva, Nada, additional, Casadei, Roberto, additional, Maraldi, Marco, additional, Ercolani, Giorgio, additional, Cavaliere, Davide, additional, Pacilio, Carlo Alberto, additional, Pieri, Federica, additional, Foca, Flavia, additional, Bongiovanni, Alberto, additional, Ranallo, Nicoletta, additional, Calpona, Sebastiano, additional, Frassineti, Giovanni Luca, additional, Ibrahim, Toni, additional, and Mercatali, Laura, additional

Published
2023
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44. HRAS overexpression predicts response to Lenvatinib treatment in gastroenteropancreatic neuroendocrine tumors

Author

Liverani, Chiara, primary, Spadazzi, Chiara, additional, Ibrahim, Toni, additional, Pieri, Federica, additional, Foca, Flavia, additional, Calabrese, Chiara, additional, De Vita, Alessandro, additional, Miserocchi, Giacomo, additional, Cocchi, Claudia, additional, Vanni, Silvia, additional, Ercolani, Giorgio, additional, Cavaliere, Davide, additional, Ranallo, Nicoletta, additional, Chiadini, Elisa, additional, Prisinzano, Giovanna, additional, Severi, Stefano, additional, Sansovini, Maddalena, additional, Martinelli, Giovanni, additional, Bongiovanni, Alberto, additional, and Mercatali, Laura, additional

Published
2023
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49. Dysbiosis and Gastrointestinal Surgery: Current Insights and Future Research

Author

Gibiino, Giulia, primary, Binda, Cecilia, additional, Cristofaro, Ludovica, additional, Sbrancia, Monica, additional, Coluccio, Chiara, additional, Petraroli, Chiara, additional, Jung, Carlo Felix Maria, additional, Cucchetti, Alessandro, additional, Cavaliere, Davide, additional, Ercolani, Giorgio, additional, Sambri, Vittorio, additional, and Fabbri, Carlo, additional

Published
2022
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50. Minimally invasive vs. open segmental resection of the splenic flexure for cancer: a nationwide study of the Italian Society of Surgical Oncology-Colorectal Cancer Network (SICO-CNN)

Author

Degiuli, Maurizio, primary, Ortenzi, Monica, additional, Tomatis, Mariano, additional, Puca, Lucia, additional, Cianflocca, Desiree, additional, Rega, Daniela, additional, Maroli, Annalisa, additional, Elmore, Ugo, additional, Pecchini, Francesca, additional, Milone, Marco, additional, La Mendola, Roberta, additional, Soligo, Erica, additional, Deidda, Simona, additional, Spoletini, Domenico, additional, Cassini, Diletta, additional, Aprile, Alessandra, additional, Mineccia, Michela, additional, Nikaj, Herald, additional, Marchegiani, Francesco, additional, Maiello, Fabio, additional, Bombardini, Cristina, additional, Zuolo, Michele, additional, Carlucci, Michele, additional, Ferraro, Luca, additional, Falato, Armando, additional, Biondi, Alberto, additional, Persiani, Roberto, additional, Marsanich, Patrizia, additional, Fusario, Daniele, additional, Solaini, Leonardo, additional, Pollesel, Sara, additional, Rizzo, Gianluca, additional, Coco, Claudio, additional, Di Leo, Alberto, additional, Cavaliere, Davide, additional, Roviello, Franco, additional, Muratore, Andrea, additional, D’Ugo, Domenico, additional, Bianco, Francesco, additional, Bianchi, Paolo Pietro, additional, De Nardi, Paola, additional, Rigamonti, Marco, additional, Anania, Gabriele, additional, Belluco, Claudio, additional, Polastri, Roberto, additional, Pucciarelli, Salvatore, additional, Gentilli, Sergio, additional, Ferrero, Alessandro, additional, Scabini, Stefano, additional, Baldazzi, Gianandrea, additional, Carlini, Massimo, additional, Restivo, Angelo, additional, Testa, Silvio, additional, Parini, Dario, additional, De Palma, Giovanni Domenico, additional, Piccoli, Micaela, additional, Rosati, Riccardo, additional, Spinelli, Antonino, additional, Delrio, Paolo, additional, Borghi, Felice, additional, Guerrieri, Marco, additional, and Reddavid, Rossella, additional

Published
2022
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