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242 results on '"Cauldwell, Matthew"'

1. Prevalence of pre-eclampsia and adverse pregnancy outcomes in women with pre-existing cardiomyopathy: a multi-centre retrospective cohort study

Author

Ormesher, Laura, Vause, Sarah, Higson, Suzanne, Roberts, Anna, Clarke, Bernard, Curtis, Stephanie, Ordonez, Victoria, Ansari, Faiza, Everett, Thomas R., Hordern, Claire, Mackillop, Lucy, Stern, Victoria, Bonnett, Tessa, Reid, Alice, Wallace, Suzanne, Oyekan, Ebruba, Douglas, Hannah, Cauldwell, Matthew, Reddy, Maya, Palmer, Kirsten, Simpson, Maggie, Brennand, Janet, Minns, Laura, Freeman, Leisa, Murray, Sarah, Mary, Nirmala, Castleman, James, Morris, Katie R., Haslett, Elizabeth, Cassidy, Christopher, Johnstone, Edward D., and Myers, Jenny E.

Published
2023
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3. Guidelines on general surgical emergencies in pregnancy

Author

Kenington, J Cleo, primary, Pellino, Gianluca, additional, Iqbal, Muhammad R, additional, Ahmed, Nauman, additional, Halahakoon, V Chandima, additional, Zaborowski, Alexandra M, additional, Rajebhosale, Ramprasad, additional, Gabriel, Jonathan, additional, Coroyannakis, Christina, additional, Cauldwell, Matthew, additional, Mayahi, Lila, additional, Dent, Kara, additional, Elton, Chris, additional, Mahawar, Kamal, additional, Sheen, Aali J, additional, Macutkiewicz, Christian, additional, and Lockwood, Sonia, additional

Published
2024
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5. The management of pregnancy and labour in women with cardiac disease

Author

Cauldwell, Matthew, Johnson, Mark, and Steer, Philip

Subjects
618.3
Abstract

Within my thesis I have shown that women with congenital heart disease are amenable to preconception counselling, but that many women are not referred to see a specialist cardiologist or obstetrician prior to pregnancy. Women with more severe forms of heart disease such as a Fontan repair have worse obstetric outcomes with high rates of miscarriage, preterm delivery and postpartum haemorrhage (PPH), hence the importance of comprehensive counselling prior to pregnancy. When women are counselled prior to pregnancy regarding the potential risks that they face, I have shown that the quoted risk of an adverse event assessed by an experienced clinician has a better correlation with actual outcome than other validated scoring systems such as the modified WHO score. Women with congenital heart disease are at much greater than average risk of postpartum haemorrhage (PPH). My analysis has shown that after correcting for known risk factors for PPH, women with a Fontan repair are at the highest risk of increased blood loss, and that low molecular weight heparin at both a prophylactic and therapeutic dose is associated with higher rates of PPH even when stopped at an appropriate time prior to delivery. I have focussed on the management of labour in women with heart disease, in particular of the second and third stages. Having shown that a restricted second stage for women with heart disease recommended by the multidisciplinary team (MDT) is often not adhered to in our actual clinical practice, my pilot study showed that there was only a modest measured haemodynamic effect of pushing (bearing down), with a small but significant increase in maternal heart rate in the active second stage of labour. I have found from a literature review and from our own historical dataset that the practice of a restricted oxytocin regimen for the management of the third stage (designed to minimise cardiovascular side-effects) is associated with greater rates of PPH, mainly due to uterine atony. In a prospective cohort study, women with heart disease were allocated to either a low dose infusion or a combination of the low dose infusion with an initial bolus of 2IU of oxytocin over ten minutes; those receiving the additional oxytocin had a significantly lower volume of blood loss and rate of PPH. Importantly, the women receiving the higher dose of oxytocin had no measured deleterious cardiovascular side effects.

Published
2017
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7. Best practice recommendations for medically assisted reproduction in patients with known cardiovascular disease or at high risk of cardiovascular disease

Author

English, Kate, primary, Frise, Charlotte, additional, Trinder, Johanna, additional, Cauldwell, Matthew, additional, Simpson, Maggie, additional, Adamson, Dawn, additional, Elton, Chris, additional, Burns, Gwenda, additional, Choudhary, Meenakshi, additional, Nathanson, Mike, additional, Robert, Leema, additional, Moore, Jim, additional, O’Brien, Pat, additional, and Pundir, Jyotsna, additional

Published
2024
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8. Contributors

Author

Arrigo, Mattia, primary, Azibani, Feriel, additional, Bauersachs, Johann, additional, Briton, Olivia, additional, Cauldwell, Matthew, additional, Chin, Ashley, additional, van der Meer, P., additional, Farhan, Hasan Ali, additional, Goland, Sorel, additional, Hähnle, Julia, additional, Hähnle, Lina, additional, Hilfiker-Kleiner, Denise, additional, Hoevelmann, Julian, additional, Jackson, A.M., additional, Johnson, Mark, additional, Karaye, Kamilu Musa, additional, König, Tobias, additional, Mebazaa, Alexandre, additional, Millar, Rob Scott, additional, Moulig, Valeska Abou, additional, Mouquet, Frederic, additional, Petrie, M.C., additional, Petrie, Mark, additional, Pfeffer, Tobias, additional, Sliwa, Karen, additional, Tibazarwa, K., additional, Viljoen, Charle, additional, and Yaseen, Israa Fadhil, additional

Published
2021
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15. Direct current cardioversion in pregnancy: a multicentre study.

Author

Cauldwell, Matthew, Adamson, Dawn, Bhatia, Kaliash, Bhagra, Catriona, Bolger, Aidan, Everett, Thomas, Fox, Caroline, Girling, Joanna, Head, Catherine, English, Kate, Hudsmith, Lucy, James, Rachael, Johnson, Mark, MacKiliop, Lucy, McAuliffe, Fionnuala M., Mariappa, Gayathri, Orchard, Elizabeth, O'Brien, Maggy, Siddiqui, Farah, and Simpson, Lydia

Subjects
*ELECTRIC countershock, *SUPRAVENTRICULAR tachycardia, *FETAL monitoring, *ATRIAL flutter, *PREGNANCY, *PREGNANT women
Abstract

Objective: Direct current cardioversion (DCCV) in pregnancy is rarely required and typically only documented in single case reports or case series. A recent UK confidential enquiry reported on several maternal deaths where appropriate DCCV appeared to have been withheld. Design: Retrospective cohort study. Setting: Seventeen UK and Ireland specialist maternity centres. Sample: Twenty‐seven pregnant women requiring DCCV in pregnancy. Main outcome measures: Maternal and fetal outcomes following DCCV. Results: Twenty‐seven women had a total of 29 DCCVs in pregnancy. Of these, 19 (70%) initial presentations were to Emergency Departments and eight (30%) to maternity settings. There were no maternal deaths. Seventeen of the women (63%) had a prior history of heart disease. Median gestation at DCCV was 28 weeks, median gestation at delivery was 35 weeks, with a live birth in all cases. The abnormal heart rhythms documented at the first cardioversion were atrial fibrillation in 12/27 (44%) cases, atrial flutter in 8/27 (30%), supraventricular tachycardia in 5/27 (19%) and atrial tachycardia in 2/27 (7%). Fetal monitoring was undertaken following DCCV on 14/29 (48%) occasions (10 of 19 (53%) at ≥26 weeks) and on 2/29 (7%) occasions, urgent delivery was required post DCCV. Conclusions: Direct current cardioversion in pregnancy is rarely required but should be undertaken when clinically indicated according to standard algorithms to optimise maternal wellbeing. Once the woman is stable post DCCV, gestation‐relevant fetal monitoring should be undertaken. Maternity units should develop multidisciplinary processes to ensure pregnant women receive the same standard of care as their non‐pregnant counterparts. [ABSTRACT FROM AUTHOR]

Published
2023
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19. Reproductive health after thoracic transplantation: An ISHLT expert consensus statement

Author

Kittleson, Michelle M., primary, DeFilippis, Ersilia M., additional, Bhagra, Catriona J., additional, Casale, Jillian P., additional, Cauldwell, Matthew, additional, Coscia, Lisa A., additional, D'Souza, Rohan, additional, Gaffney, Nicole, additional, Gerovasili, Vicky, additional, Ging, Patricia, additional, Horsley, Kristin, additional, Macera, Francesca, additional, Mastrobattista, Joan M., additional, Paraskeva, Miranda A., additional, Punnoose, Lynn R., additional, Rasmusson, Kismet D., additional, Reynaud, Quitterie, additional, Ross, Heather J., additional, Thakrar, Mitesh V., additional, and Walsh, Mary Norine, additional

Published
2022
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24. Pregnancy and Spontaneous Coronary Artery Dissection: Lessons From Survivors and Nonsurvivors

Author

Chan, Nathan, primary, Premawardhana, Diluka, additional, Al-Hussaini, Abtehale, additional, Wood, Alice, additional, Bountziouka, Vasiliki, additional, Kotecha, Deevia, additional, Swahn, Eva, additional, Palmefors, Henning, additional, Pagonis, Christos, additional, Lawesson, Sofia Sederholm, additional, Kądziela, Jacek, additional, Garcia-Guimarães, Marcos, additional, Alfonso, Fernando, additional, Escaned, Javier, additional, Macaya, Fernando, additional, Santás, Melisa, additional, Cerrato, Enrico, additional, Maas, Angela H.E.M., additional, Hlinomaz, Ota, additional, Bogale, Nigussie, additional, Cortese, Bernardo, additional, Cheng, Mavis, additional, Bolger, Aidan, additional, Hussain, Shazia T., additional, Samani, Nilesh J., additional, Knight, Marian, additional, Cauldwell, Matthew, additional, and Adlam, David, additional

Published
2022
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25. Pregnancy and Spontaneous Coronary Artery Dissection : Lessons From Survivors and Nonsurvivors

Author

Chan, Nathan, Premawardhana, Diluka, Al-Hussaini, Abtehale, Wood, Alice, Bountziouka, Vasiliki, Kotecha, Deevia, Swahn, Eva, Palmefors, Henning, Pagonis, Christos, Sederholm Lawesson, Sofia, Kadziela, Jacek, Garcia-Guimaraes, Marcos, Alfonso, Fernando, Escaned, Javier, Macaya, Fernando, Santas, Melisa, Cerrato, Enrico, Maas, Angela H. E. M., Hlinomaz, Ota, Bogale, Nigussie, Cortese, Bernardo, Cheng, Mavis, Bolger, Aidan, Hussain, Shazia T., Samani, Nilesh J., Knight, Marian, Cauldwell, Matthew, Adlam, David, Chan, Nathan, Premawardhana, Diluka, Al-Hussaini, Abtehale, Wood, Alice, Bountziouka, Vasiliki, Kotecha, Deevia, Swahn, Eva, Palmefors, Henning, Pagonis, Christos, Sederholm Lawesson, Sofia, Kadziela, Jacek, Garcia-Guimaraes, Marcos, Alfonso, Fernando, Escaned, Javier, Macaya, Fernando, Santas, Melisa, Cerrato, Enrico, Maas, Angela H. E. M., Hlinomaz, Ota, Bogale, Nigussie, Cortese, Bernardo, Cheng, Mavis, Bolger, Aidan, Hussain, Shazia T., Samani, Nilesh J., Knight, Marian, Cauldwell, Matthew, and Adlam, David

Abstract

n/a, Funding Agencies|British Heart Foundation [PG/13/96/30608]; National Institute for Health and Care Research rare disease translational collaboration; Leicester National Institute for Health and Care Research Biomedical Research Center; Beat SCAD

Published
2022
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29. Pregnancy following personalised aortic root support in Marfan syndrome.

Author

Coroyannakis, Christina, Tome, Maite, Watt-Coote, Ingrid, and Cauldwell, Matthew

Subjects
ECHOCARDIOGRAPHY, MARFAN syndrome, GENETIC testing, BLOOD vessel prosthesis, PUERPERIUM, FERTILIZATION in vitro, CESAREAN section
Abstract

Marfan syndrome (MFS) is linked with adverse pregnancy events, one of the most significant being aortic dissection. We present a case of a woman with MFS with prior aortic root dilatation who opted for a Personalised External Aortic Root Support (PEARS). To date, she is only the fifth woman to have had this valve-sparing procedure prior to pregnancy. We outline her care in a tertiary centre with multidisciplinary expertise, from preconception through to the postpartum period. [ABSTRACT FROM AUTHOR]

Published
2023
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32. Maternal and fetal outcomes in women with cerebrovascular malformations in pregnancy: A multicentre retrospective cohort study

Author

Cauldwell, Matthew, primary, Bredaki, Emma, additional, Dassan, Pooja, additional, Dhanjal, Mandish K., additional, Kaler, Mandeep, additional, Madipola, Nissanka, additional, Mahmud, Mohammad, additional, Paviour, Dominic, additional, Senvar, Naz, additional, de Silva, Rajith, additional, Watt‐Coote, Ingrid, additional, Williams, David, additional, Yulia, Angela, additional, and Steer, Philip J., additional

Published
2021
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40. Acute severe heart failure in pregnancy: A clinical challenge and review of the literature.

Author

Ellison, Lili, Sundaram, Ash, Coroyannikis, Christina, and Cauldwell, Matthew

Subjects
CARDIOMYOPATHIES, SEVERITY of illness index, PREECLAMPSIA, HEART failure, PREGNANCY
Abstract

Pregnancy-associated myocarditis is uncommon and remains poorly described. The spectrum of the disorder is wide, with the severe cases culminating in heart failure, cardiogenic shock and even maternal death. Diagnosis is typically made on imaging, serology and endocardiac biopsy findings with treatment being directed towards the underlying cause. We describe a case of likely peripartum myocarditis associated with severe early-onset pre-eclampsia. [ABSTRACT FROM AUTHOR]

Published
2022
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42. Maternal and fetal outcomes in women with cerebrovascular malformations in pregnancy: A multicentre retrospective cohort study.

Author

Cauldwell, Matthew, Bredaki, Emma, Dassan, Pooja, Dhanjal, Mandish K., Kaler, Mandeep, Madipola, Nissanka, Mahmud, Mohammad, Paviour, Dominic, Senvar, Naz, de Silva, Rajith, Watt‐Coote, Ingrid, Williams, David, Yulia, Angela, and Steer, Philip J.

Abstract

Objective: To determine maternal, obstetric and neonatal outcomes in a cohort of women with cerebrovascular malformations (CVMs) that include arterial venous malformations (AVMs) and cavernomas. Design: Retrospective cohort study. Setting: Six specialist centres managing pregnant women with neurological disorders. Population: Sixty‐three women with CVMs in 83 pregnancies of ≥20 completed weeks' gestation. Methods: Retrospective case notes review. Main outcome measures: Neurological outcomes including rates of acute cerebral bleeding in pregnancy and reported seizures during pregnancy. Maternal outcomes included number of women with a livebirth and the proportion of women being delivered by caesarean section. Results: Most women had a good pregnancy outcome with high rates of vaginal delivery (73%) at term. There were no maternal deaths. Six women had an acute cerebral bleed, all of whom were delivered by planned caesarean section. In total, ten women had seizures in pregnancy (of whom four also had a bleed). Six (7%) babies were admitted to a neonatal unit. There was no significant difference in outcomes between women with AVMs and those with cavernomas. Conclusion: In the majority of cases, pregnancy outcomes were favourable, with most women having a vaginal delivery. All cases of cerebral bleeds that occurred were at a remove from the peripartum period. Women with cerebrovascular malformations have high rates of vaginal delivery. Women with cerebrovascular malformations have high rates of vaginal delivery. [ABSTRACT FROM AUTHOR]

Published
2022
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45. The impact of electronic patient records on workflow in general practice

Author

Cauldwell, Matthew, Beattie, Caroline, Cox, Benita, Denby, William, Ede-Golightly, Jessica, and Linton, Fiona

Subjects
Hospitals -- Administration, Medical records -- Information management -- Usage -- Technology application, Family medicine -- Management -- Technology application -- Usage, Computers and office automation industries, Health, Company business management, Company systems management, Technology application, Hospital/clinic administration software, Management, Usage, Information management
Abstract

The Patient Access to Electronic Healthcare Records System (PAERS) allows patients to register their arrival at a GP's surgery and to view their healthcare record electronically whilst in the waiting [...]

Published
2007

48. Pregnancy outcomes for women with primary sclerosis cholangitis and primary binary cholangitis

Author

Cauldwell, Matthew, primary, Mackie, Fiona, additional, Steer, Philip, additional, Heneghan, Michael, additional, Baalman, Jelle, additional, Brennand, Janet, additional, Johnson, Tracey, additional, Dockree, Sam, additional, Hedley, Catherine, additional, Jarvis, Sheba, additional, Khan, Sheeba, additional, McAuliffe, Fionnuala, additional, Mackillop, Lucy, additional, Penna, Leonie, additional, Smith, Belinda, additional, Trivedi, Palak, additional, Verma, Sumita, additional, Westbrook, Rachel, additional, Winfield, Sarah, additional, and Williamson, Catherine, additional

Published
2020
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49. Maternal and neonatal outcomes in women with history of coronary artery disease

Author

Cauldwell, Matthew, primary, Steer, Philip J, additional, von Klemperer, Katherine, additional, Kaler, Mandeep, additional, Grixti, Sarah, additional, Hale, Joanna, additional, O'Heney, Josie, additional, Warriner, David, additional, Curtis, Stephanie, additional, Mohan, Aarthi R, additional, Dockree, Samuel, additional, Mackillop, Lucy, additional, Head, Catherine E G, additional, Sterrenberg, Monique, additional, Wallace, Suzanne, additional, Freeman, Leisa J, additional, Patridge, Gemma, additional, Baalman, Jelle H, additional, McAuliffe, Fionnuala M, additional, Simpson, Margaret, additional, Walker, Niki, additional, Girling, Joanna, additional, Siddiqui, Farah, additional, Bolger, Aidan P, additional, Bredaki, Foteini, additional, Walker, Fiona, additional, Vause, Sarah, additional, Gatzoulis, Michael A, additional, Johnson, Mark R, additional, and Roberts, Anna, additional

Published
2019
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50. Maternal and fetal outcomes in pregnancies complicated by Marfan syndrome

Author

Cauldwell, Matthew, primary, Steer, Philip J, additional, Curtis, Stephanie L, additional, Mohan, Aarthi, additional, Dockree, Samuel, additional, Mackillop, Lucy, additional, Parry, Helen M, additional, Oliver, James, additional, Sterrenberg, Monique, additional, Wallace, Suzanne, additional, Malin, Gemma, additional, Partridge, Gemma, additional, Freeman, Leisa J, additional, Bolger, Aidan P, additional, Siddiqui, Farah, additional, Wilson, Dirk, additional, Simpson, Margaret, additional, Walker, Niki, additional, Hodson, Ken, additional, Thomas, Katherine, additional, Bredaki, Foteini, additional, Mercaldi, Rebecca, additional, Walker, Fiona, additional, and Johnson, Mark R, additional

Published
2019
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