Search

Your search keyword '"Caula, Caroline"' showing total 8 results
Start Over Author "Caula, Caroline"
8 results on '"Caula, Caroline"'

2. Early formative objective structured clinical examinations for students in the pre-clinical years of medical education: A non-randomized controlled prospective pilot study

Author

Ouldali, Naïm, primary, Le Roux, Enora, additional, Faye, Albert, additional, Leblanc, Claire, additional, Angoulvant, François, additional, Korb, Diane, additional, Delcour, Clémence, additional, Caula, Caroline, additional, Wohrer, Delphine, additional, Rybak, Alexis, additional, Delafoy, Manon, additional, Carrié, Claire, additional, Strullu, Marion, additional, Oualha, Mehdi, additional, Levy, Romain, additional, Mimoun, Camille, additional, Griffon, Lucie, additional, Nuzzo, Alexandre, additional, Eyraud, Clara, additional, Levy, Michael, additional, and Ellul, Pierre, additional

Published
2023
Full Text
View/download PDF

3. A French study of cocaine intoxication/exposure in children (2010–2020)

Author

Claudet, Isabelle, primary, Caula, Caroline, additional, Gallart, Jean-Christophe, additional, Tourniaire, Gaelle, additional, Lerouge-Bailhache, Marion, additional, Michard-Lenoir, Anne-Pascale, additional, Tran, Antoine, additional, Maleterre, Aline, additional, Huet, Frédéric, additional, Dufour, Damien, additional, Billaud, Nicolas, additional, David, Alexandra, additional, Di Patrizio, Marie, additional, Granjon, Mathilde, additional, Benoist, Grégoire, additional, Laguille, Christine, additional, Guitteny, Marie-Aline, additional, Balençon, Martine, additional, Vrignaud, Bénédicte, additional, Basmaci, Romain, additional, Dampfhoffer, Marie, additional, Dubos, François, additional, Chappuy, Hélène, additional, Minodier, Philippe, additional, Médiamolle, Nicolas, additional, and Bréhin, Camille, additional

Published
2023
Full Text
View/download PDF

7. Évaluation de la tolérance de la leucoréduction chez les patients atteints de coqueluche maligne admis en réanimation pédiatrique au Kremlin Bicêtre de 2001 à 2018

Author

Caula, Caroline, Université Paris Descartes - Faculté de Médecine (UPD5 Médecine), Université Paris Descartes - Paris 5 (UPD5), and Pierre Tissières

Subjects
Malignant, Sévère, Coqueluche, MESH: Whooping Cough, Death, Leucoréduction, Leukodepletion, Facteurs de risque, Pertussis, Risk factors, Pédiatrique, MESH: Self Tolerance, ICU, MESH: Pediatrics, Décès, Tolérance, MESH: Resuscitation, Children, Réanimation, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology, Maligne
Abstract

Pertussis remains a life-threatening disease in children under 3 months of age without vaccination. Cardio-respiratory failures and pulmonary hypertention in severe pertussis are believed to be linked to white blood cell aggregates in lung microvasculature. Leukodepletion, by fighting against this accumulation, seems to improve those patients survival rate in various publications. The purpose of this retrospective monocentric study is to assess the tolerance of leukodepletion and the risk factor of death among patients hospitalized in Kremlin Bicêtre ICU for pertussis from 2001 to 2018. 60 children were hospitalized for pertussis during this period. 8 died, representing a mortality rate of 13.3%. The main risk factors for deaths were young age (p=0.006), small weight (p=0.025), tachycardia (p=0.024), peripheral hypoperfusion (p

Published
2019

8. Biological impact of manual blood exchange in malignant Bordetella pertussis infection in infants.

Author

Cousin VL, Caula C, and Tissières P

Abstract

Background and Objectives: Manual blood exchange (MBE) is a leukoreduction therapy for hyperleukocytosis in Bordetella spp., Infection: We describe the impact of BE on clinical and biological parameters in critically ill children with malignant pertussis., Materials and Methods: This is a monocentric retrospective review of patients with malignant pertussis infection treated with MBE. It describes the evolution of haemodynamic, ventilatory, haematologic and metabolic characteristics before and after MBE., Results: Between January 2006 and December 2021, nine patients (median age 43 days, range: 13-80 days) had 16 MBE for malignant pertussis. All patients were mechanically ventilated, and 7/9 patients developed pulmonary hypertension during their paediatric intensive care unit (PICU) stay. Overall, 3/9 patients survived, and the mean PICU length of stay was 8.5 days (range: 1-52 days). We found a significant reduction of the leukocyte count (pre-MBE: 61.8 G/L [interquartile range (IQR): 55.8-74.8] vs. post-MBE: 19.4 G/L [IQR: 17.7-24.1]; p ≤ 0.001) and significant oxygenation improvement (pre-MBE SpO 2 /FiO 2 : 190 [IQR: 106-200] vs. post-MBE SpO 2 /FiO 2 : 242 [IQR: 149-250]; p = 0.03). The main side effects were a significant reduction of thrombocytes (pre-MBE: 411 G/L [IQR: 166.5-563.5] vs. post-MBE: 66 G/L [IQR: 46-82.5]; p = <0.001) and of ionized calcium (iCa) (pre-MBE iCa: 1.3 [IQR: 1.22-1.37] vs. post-MBE iCa: 1.25 [IQR: 1.85-2.24]; p = 0.03)., Conclusion: MBE efficiently reduces leukocytes and improves oxygenation in severe Bordetella pertussis infection in infants. Careful monitoring of calcium and thrombocytes seems mandatory., (© 2024 The Author(s). Vox Sanguinis published by John Wiley & Sons Ltd on behalf of International Society of Blood Transfusion.)

Published
2024
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results