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Abstract Previous research investigated the impact of psychosocial predictors (e.g. attitude, social and moral norm, perceived behavioral control, intention) on sustainable clothing purchasing. To date, no studies considered whether proenvironmental self-identity moderates the effects of these predictors on behavior. In this study, we adopted an intrapersonal approach and a longitudinal design to assess the moderating role of proenvironmental self-identity in predicting intentions and behaviors, considering gender differences. 250 participants completed an initial questionnaire on the predictors of three sustainable clothing purchasing. A month later, they filled out a second questionnaire to self-assess these behaviors. The results showed that social and internalized norms (moral norms) were notably influential of participants’ intentions. Affective attitude influenced behavior positively, while cognitive attitude had a negative influence. When considering the moderating role of proenvironmental self-identity, significant gender differences emerged. Women with a weak proenvironmental self-identity expressed a higher intention to purchase sustainable clothing when they had high affective attitudes and descriptive norm but low cognitive attitudes. Women with a strong proenvironmental self-identity intended to purchase sustainable clothing when they had high moral norms and cognitive attitudes but low descriptive norm. Man with a weak proenvironmental self-identity and high positive affective attitude increased their future SCP.

The advancements of technological devices and software are putting mixed reality in the frontline of teaching medical personnel. The Microsoft ® HoloLens 2 ® offers a unique 3D visualization of a hologram in a physical, real environment and allows the urologists to interact with it. This review provides a state-of-the-art analysis of the applications of the HoloLens ® in a medical and healthcare context of teaching through simulation designed for medical students, nurses, residents especially in urology. Our objective has been to perform a comprehensively analysis of the studies in PubMed/Medline database from January 2016 to April 2023. The identified articles that researched Microsoft HoloLens, having description of feasibility and teaching outcomes in medicine with an emphasize in urological healthcare, have been included. The qualitative analysis performed identifies an increasing use of HoloLens in a teaching setting that covers a great area of expertise in medical sciences (anatomy, anatomic pathology, biochemistry, pharmacogenomics, clinical skills, emergency medicine and nurse education, imaging), and above these urology applications (urological procedures and technique, skill improvement, perception of complex renal tumors, accuracy of calyx puncture guidance in percutaneous nephrolithotomy and targeted biopsy of the prostate) can mostly benefit from it. The future potential of HoloLens technology in teaching is immense. So far, studies have focused on feasibility, applicability, perception, comparisons with traditional methods, and limitations. Moving forward, research should also prioritize the development of applications specifically for urology. This will require validation of needs and the creation of adequate protocols to standardize future research efforts.

Ruminants are often considered less susceptible to mycotoxins than monogastrics, owing to rumen microflora converting mycotoxins to less toxic compounds or several compounds present in the rumen-reticulum compartment, being able to bind the mycotoxin “mother” molecule that make them unavailable for absorption process in the gastro-intestinal tract of host animals. However, if ruminants consume feed contaminated by mycotoxins for long periods, their growth, development, and fertility can be compromised. Among regulated mycotoxins, the most studied and known for their effects are aflatoxins (AFs) AFB1, AFB2, AFG1 and AFG2, as well as the AFM1 for its high importance in dairy sector, deoxynivalenol (DON) and its metabolites 3/15 acetyl-DON and 3-glucoside DON, T-2 and HT-2 toxins, zearalenone, fumonisins, in particular that belong to the B class, and ochratoxin A. Furthermore, because of the emergence of multiple emerging mycotoxins that are detectable in feed utilised in ruminant diets, such as ensiled forage, there is now a growing focus on investigating these compounds by the scientific community to deepen their toxicity for animal health. Despite the enhancement of research, it is remarkable that there is a paucity of in vivo trials, as well as limited studies on nutrient digestibility and the impact of these molecules on rumen and intestinal functions or milk yield and quality. In this review, recent findings regarding the occurrence of regulated and emerging mycotoxins in forage and their possible adverse effects on dairy cattle are described, with special emphasis on animal performance and on rumen functionality.

This paper addresses the crucial challenge of maintaining the directed graph topology in multi-robot systems, particularly when operating under limited field-of-view constraints and with a lack of communication among robots. Traditional methods for multi-robot coordination rely heavily on inter-robot communication, which may not always be feasible, particularly in constrained or hostile environments. Our work presents a novel distributed control algorithm that leverages Control Barrier Functions (CBFs) to maintain the graph topology of a multi-robot system based solely on local, onboard sensor data. This approach is particularly beneficial in situations where external communication channels are disrupted or unavailable. The key contributions of this research are threefold: First, we design a novel control algorithm that efficiently maintains the graph topology in multi-robot systems using CBFs, which operate on neighbor detection data. Second, we perform an experimental evaluation of the algorithm, demonstrating its efficacy in controlling the flight of a team of drones using only local robot data. Third, we apply our methodology to a distributed coverage control scenario, showing that our approach can effectively manage a multi-robot system using only local information.

Sociocultural Attitudes Towards Appearance Questionnaire-Social Media (SATAQ-SM) is a self-administered questionnaire for the evaluation of social media pressure and internalization of beauty standards. This study aims to validate the SATAQ-SM an adapted Italian version of the Sociocultural Attitudes Towards Appearance Questionnaire third version (SATAQ-3). Confirmatory factor analysis was used to investigate whether the empirical data fitted the four-factor structure of SATAQ-3. Assessment of goodness-of-fit was based on standard model fit criteria: relative χ2 value (χ2/df), Root Mean-Squared Error of Approximation (RMSEA), Comparative Fit Index (CFI) and Tucker–Lewis Index (TLI). Internal consistency was assessed using McDonald’s omega. Criterion validity was calculated by correlating the SATAQ-SM factors scores with the total score of the Rosenberg self-esteem scale (RSES) and Eating Attitudes Test (EAT-26). Four-hundred and eighty-five females agreed to participate in the study. The four-factor model appears to be confirmed by the fit indices: χ2/df = 3.73, RMSEA = 0.07, CFI = 0.99 and TLI = 0.99. All the items defining the four factors had a factor loading of ≥0.40. McDonald’s omega of the entire questionnaire was equal to 0.95 and for the four subscales it did not assume values lower than 0.81. The correlations between the factor score of SATAQ-SM and the RSES were all negative and statistically relevant (p

Twelve Holstein (HOL), 9 Brown Swiss (BRO), and 9 Simmental (SIM) dairy cows raised in the same barn and managed identically were enrolled to characterise the responses to the transition period. From −21 to 28 d from calving (DFC), body condition score (BCS) and milk yield were measured, and blood samples were collected to assess plasma biomarkers of metabolism, minerals, liver function, inflammation, and oxidative status. Compared with SIM, HOL and BRO had higher milk yield during the first week of lactation. HOL had the highest milk yield from the second to the fourth week and the lowest BCS at 28 DFC. SIM had the highest BCS and the highest plasma creatinine and P, reflecting a greater attitude to gain muscle mass. Compared with SIM, BRO and HOL had lower plasma fructosamine, indicating reduced glucose availability driven by lactose synthesis. SIM had the mildest acute phase response at the onset of lactation, as suggested by the lowest ceruloplasmin concentration. HOL had the highest cholesterol and paraoxonase concentrations, and the greatest interleukin-1β production by leukocytes following ex-vivo stimulation, suggesting that they had the quickest resolution of the acute phase response due to the fastest immune cell activation. BRO had the highest concentration of reactive oxygen metabolites, ceruloplasmin, bilirubin, glutamate-oxaloacetate transaminase, γ-glutamyl transferase, and β-hydroxybutyrate, and the lowest concentration of paraoxonase, reflecting the strongest activation of leukocytes and the most severe acute phase response. Together, these results highlight different metabolic and inflammatory conditions around calving in the three explored breeds.HIGHLIGHTS Holstein, Brown Swiss, and Simmental are dairy breeds selected for different purposes. These three breeds have different productivity, and metabolic and inflammatory responses during the transition period. Understanding the differences among breeds might improve their management, nutrition, and productivity in commercial dairy farms.

Our paper investigates Belgian young peoples’ discussions about climate change, specifically how they distance themselves from various dimensions related to climate issues. The study includes a pluridisciplinary analysis combining sociological, linguistic and semiotic approaches to process textual data collected in 2022 from six focus groups organised within local youth associations. This study focuses on 33 socially and economically diverse young people who joined a youth club. The paper explores the strategies employed by the respondents to distance themselves from climate change issues. It sheds light on various aspects related to climate distancing: How young people embody their vision of climate change through voice-switching, how societal norms and beliefs influence them, how they perceive the global impact of the changes, and how education plays a role in the issue of climate change. The study highlights the barriers, paradoxes and conflicts that hinder young people’s active involvement in addressing climate change. It goes on to propose a set of recommendations aimed at transforming these barriers into actionable steps that can drive positive change. By identifying and addressing the contributing factors to climate distancing, this research offers potential pathways for empowering young people to become more engaged in the fight against climate change.

Bacillus cereus (hereafter, B. cereus) poisoning often arises from the consumption of Ready-To-Reheat vegetable soups in which an intensive growth of the vegetative cells of B. cereus take place. The market for these soups is increasing significantly worldwide. For the producer it is important to determine if soups can promote the growth of B. cereus, by calculating its growth potential. We can achieve this goal by carrying out an efficient challenge test. In our study we have designed and performed a challenge test in three batches of an emmer (Triticum monococcum) and vegetable soup that undergo a second pasteurization treatment after packaging. We found out that under refrigeration conditions B. cereus is unable to multiply in the soup, instead, under conditions of thermal abuse, B. cereus can grow during 90 days of shelf life with a growth potential of 0.82 logarithms. It is essential to keep the entire production phase under control using effective GMP (Good Manufacturing Practices) and GHP (Good Hygiene Practices) measures, to ensure that the freshly produced soups contain low loads of the spores of B. cereus. In this way, the vegetative cells born from the germination of the spores cannot reach the infectious dose necessary to induce the food poisoning.

This article presents a comprehensive investigation into the functionalization of methoxyphenylazobenzene using electron-directing groups located at the meta position relative to the azo group. Spectroscopic analysis of meta-functionalized azobenzenes reveals that the incorporation of electron-withdrawing units significantly influences the absorption spectra of both E and Z isomers, while electron-donating functionalities lead to more subtle changes. The thermal relaxation process from Z to E result in almost twice as prolonged for electron-withdrawing functionalized azobenzenes compared to their electron-rich counterparts. Computational analysis contributes a theoretical understanding of the electronic structure and properties of meta-substituted azobenzenes. This combined approach, integrating experimental and computational techniques, yields significant insights into the structure–property relationship of meta-substituted asymmetrical phenolazobenzenes.

The role of human activity in climate change (CC) has generated a particular enthusiasm for research, all research fields combined: these studies focus on people's perceptions and their motivation to contribute, individually or in groups, to reducing these changes. Other studies have aimed to shape communication campaigns so that they succeed in involving individuals in the fight against CC. Some of these studies have examined the links between beliefs, media use and pro-environmental habits; however, few of them have focused specifically on older people. The aim of this study is therefore to explore the links between beliefs, media use and pro-environmental habits in a sample of people aged over 60 (N = 305). The main results of this correlational study suggest that the participants in our sample consider themselves to be well informed about CC and are less disconnected from the internet and computer tools than in other older studies and use Facebook more than any other social network. Furthermore, their beliefs about CC are significantly correlated with their pro-environmental habits, and these habits do seem to be linked to their use of certain information and communication technologies. The overall results of this study, their implications and limits are reviewed in the paper's discussion section.

This article studies the relations between the rise of revivalist churches, and more globally the Christian religion, and the promotional discourses on beers in Kinshasa (Democratic Republic of the Congo) in the 1990s. We conducted in-depth socio-semiotic analyses of three commercials aired in 1993 and 1994. These analyses showed that Christian religious allusions peppered the texts of the advertisements, with references to the rhetoric of revivalist churches of the Congo and with marks of the Catholic religion, both of which we consider as euphemistic or “de-dramatizing” discourses that favour beers. These discourses make a corrective or “recategorizing” contribution (Bonhomme and Horak, 2009) to previous discourses on the depreciative nature of beer, which was (and still is) a victim in Kinshasa, due to the teachings of certain Pentecostal religious formations that are against the consumption of alcoholic beverages.

IntroductionAlthough consumers bought more local food during the changing context of pandemic COVID -19, this positive modification may not become a stable habit afterward.MethodsTo understand this change in drivers of consumers' intention to buy local food, we investigated the role of perceptions of various intrinsic and extrinsic attributes of local food, its perceived quality, price and availability, and consumers' trust in local food producers. We also investigated the role of sociodemographic variables as well as the moderating role of consumers' stage of change (i.e., absence, reduction, maintenance, and increase) in the purchase of local food.ResultsStructural equation modeling results on a representative sample of Italian consumers (N = 511) showed that local food availability is the main driver of purchase intention (β = 0.20; p = 0.001), especially among consumers who have changed their habits toward buying local food (reduction stage = β = 0.24; increase stage = 0.30; p = 0.001). In addition, trust in local food producers was found to be a key antecedent to consumers' perceptions of local food as environmentally friendly (β = 0.57; p = 0.001), healthy (β = 0.55; p = 0.001), authentic (β = 0.58; p = 0.001), tasty (β = 0.52; p = 0.001), socially sustainable (β = 0.59; p = 0.001), and as a product with a good appearance (β = 0.55; p = 0.001).DiscussionOverall, these results improve our understanding of which food attributes should be emphasized in communication to promote the purchase of local food.

Cet article vise à montrer à l’œuvre une forme de sémiotique engagée à augmenter l’intelligibilité de phénomènes culturels et sociaux contemporains. Pour ce faire, nous proposons une analyse d’un type de discours spécifique, celui qui travaille à la valorisation du diamant de synthèse ou de laboratoire, notamment en mobilisant la prise de responsabilité éthique et environnementale de l’industrie diamantaire. Soumise, comme beaucoup d’autres secteurs économiques, à des critiques sur le plan de la durabilité et de l’éthique, l’industrie des diamants et des joyaux produit en effet des « formations discursives » multimodales parfois très intéressantes, qui expriment des formes de construction de valeur dans un contexte polémique, face aux défis de l’habitabilité de la planète. C’est en analysant ces formations qu’une forme spécifique de sémiotique, liée à l’héritage de l’école d’A. J. Greimas, peut montrer sa vivacité et sa contribution à la construction du savoir autour des enjeux cruciaux de notre ère.

ObjectiveWe investigated how physical activity can be effectively promoted with a message-based intervention, by combining the explanatory power of theory-based structural equation modeling with the predictive power of data-driven artificial intelligence.MethodsA sample of 564 participants took part in a two-week message intervention via a mobile app. We measured participants’ regulatory focus, attitude, perceived behavioral control, social norm, and intention to engage in physical activity. We then randomly assigned participants to four message conditions (gain, non-loss, non-gain, loss). After the intervention ended, we measured emotions triggered by the messages, involvement, deep processing, and any change in intention to engage in physical activity.ResultsData analysis confirmed the soundness of our theory-based structural equation model (SEM) and how the emotions triggered by the messages mediated the influence of regulatory focus on involvement, deep processing of the messages, and intention. We then developed a Dynamic Bayesian Network (DBN) that incorporated the SEM model and the message frame intervention as a structural backbone to obtain the best combination of in-sample explanatory power and out-of-sample predictive power. Using a Deep Reinforcement Learning (DRL) approach, we then developed an automated, fast-profiling strategy to quickly select the best message strategy, based on the characteristics of each potential respondent. Finally, the fast-profiling method was integrated into an AI-based chatbot.ConclusionCombining the explanatory power of theory-driven structural equation modeling with the predictive power of data-driven artificial intelligence is a promising strategy to effectively promote physical activity with message-based interventions.

Objectives: Pneumocystis jirovecii pneumonia (PCP) incidence is increasing in people without HIV. Decompensated liver cirrhosis is not currently considered a risk factor for PCP. The aim of this paper is to describe a case series of patients with decompensated liver cirrhosis and PCP. Methods: All consecutive patients hospitalized with decompensated cirrhosis and microbiology-confirmed PCP at Policlinico Modena University Hospital from January 1, 2016 to December 31, 2021 were included in our series. Results: Eight patients were included. All patients had advanced-stage liver disease with a model for end-stage liver disease score above 15 (6/8 above 20). Four were on an active orthotopic liver transplant waiting list at the time of PCP diagnosis. Five patients did not have any traditional risk factor for PCP, whereas the other three were on glucocorticoid treatment for acute-on-chronic liver failure. All patients were treated with cotrimoxazole, except two who died before the diagnosis. Five patients died (62.5%), four of them within 30 days from PCP diagnosis. Of the remaining three, one patient underwent liver transplantation. Conclusion: Although further studies are needed, liver cirrhosis can be an independent risk factor for PCP in patients with decompensated cirrhosis that is mainly due to severe alcoholic hepatitis and who are on corticosteroids therapy, and primary prophylaxis for PCP should be considered.

Past research has shown that counterfactual ("If…then…") thoughts influence causal and responsibility attribution in the judicial context. However, little is known on whether and how the use of counterfactuals in communication affects lay jurors' and judges' evaluations. In two studies, we asked mock lay jurors (Study 1) and actual judges (Study 2) to read a medical malpractice case followed by an expert witness report, which included counterfactuals focused on either the physician, the patient, or external factors. Results showed that counterfactual focus had a strong effect on both lay jurors' and judges' causal and responsibility attributions. Counterfactual focus also moderated the effect of outcome foreseeability on responsibility attribution. Discussion focuses on how counterfactual communication can direct causal and responsibility attribution and reduce the importance of other factors known to influence judicial decision-making. The potential implications of these findings in training programs and debiasing interventions are also discussed.

Abstract Background Bronchial thermoplasty (BT) is an effective treatment in severe asthma. How to select patients who more likely benefit from BT is an unmet clinical need. Moreover, mechanisms of BT efficacy are still largely unknown. We sought to determine BT efficacy and to identify potential mechanisms of response. Methods This retrospective cohort study evaluated clinical outcomes in 27 patients with severe asthma: 13 with T2-high and 14 with T2-low endotype. Expression levels of 20 genes were compared by real-time PCR in bronchial biopsies performed at the third BT session versus baseline. Clinical response was measured based on Asthma Control Questionnaire (ACQ) score

Francesco Menzella,1 Matteo Fontana,1 Marco Contoli,2 Patrizia Ruggiero,1 Carla Galeone,1 Silvia Capobelli,1 Anna Simonazzi,1 Chiara Catellani,1 Chiara Scelfo,1 Claudia Castagnetti,1 Francesco Livrieri,1 Nicola Facciolongo1 1Pulmonology Unit, Arcispedale Santa Maria Nuova, Azienda USL – IRCCS di Reggio Emilia, Reggio Emilia, Italy; 2Respiratory Section, Department of Translational Medicine, University of Ferrara, Ferrara, ItalyCorrespondence: Francesco Menzella, Pulmonology Unit, Arcispedale Santa Maria Nuova, Azienda USL – IRCCS di Reggio Emilia, Reggio Emilia, Italy, Tel +39 0522 296073, Email fmenzella@gmail.comPurpose: Treatment of severe asthma has made great strides thanks to rapid progress in understanding immune response and inflammatory pathways. This led to the advent of the first biologic for severe allergic asthma (SAA), omalizumab. Although the long-term efficacy and safety of omalizumab has been confirmed, increasingly longer follow-up data can further reinforce this evidence and potentially provide new ones, for example on any loss of efficacy or the appearance of unexpected side effects. This study reports omalizumab treatment-related outcomes after 16 years of follow-up.Patients and Methods: In this real-life retrospective study, an extension of a previous 9-year follow-up study on patients initially recruited in a clinical trial, we enrolled 8 adult patients with SAA followed-up from November 2005 to December 2021. Study subjects were selected based on omalizumab eligibility criteria.Results: Exacerbation rate significantly decreased from 3.6 ± 2.1 events in year before index date to 0.1 ± 0.4 after 32 weeks of treatment (p < 0.0001). Mean annual number of mild-to-moderate exacerbations at 16 years was 0.88 compared with 1.8 in the year before the index date and 1.1 at 32 weeks. No hospitalizations were documented during the 16-year follow-up compared to 0.3 hospitalizations/patient in the year before the index date. Respiratory function also progressively and significantly improved. Regarding patient-reported outcomes (PROs), The AQLQ and ACT significantly improved from baseline throughout the follow-up, particularly up to 9 years of follow-up. During the study, an overall reduction in doses of asthma medications was observed, with a significant OCS-sparing effect.Conclusion: Our study, the longest clinical follow-up on patients treated with anti-IgE, confirms and amplifies the results of the studies carried out so far, as they are maintained over a very long interval of time without drops in efficacy without any type of side effect.Keywords: severe allergic asthma, biologics, omalizumab, exacerbations, side effects, oral corticosteroids

In two studies, we investigated whether counterfactual messages (i.e., “If… then…”) on the economic costs of past public policies influence support for future climate change policies. In Study 1, we tested whether the effect of upward counterfactual messages depended on their referring (or not) to the COVID-19 pandemic. Results showed lower support for a future climate change policy when the past expenses evoked by the upward counterfactual messages were attributed to COVID-19. In Study 2, we combined upward counterfactuals with downward counterfactuals presenting past economic efforts to deal with the COVID-19 pandemic as a moral credit. Results showed that exposure to downward counterfactuals decreased support for climate change policies among participants with low endorsement of anti-COVID-19 measures, whereas it increased support among participants with high endorsement. Discussion focuses on the conditions under which counterfactual communication may activate cross-dimensional moral licensing or moral consistency effects, influencing support for climate change policies.