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24 results on '"Castro, Liesa"'

2. Association Between Dyscapnia, Ventilatory Variables, and Mortality in Patients With Acute Respiratory Distress Syndrome—A Retrospective Cohort Study.

Author

Braunsteiner, Josephine, Castro, Liesa, Wiessner, Christian, Grensemann, Jörn, Schroeder, Maria, Burdelski, Christoph, Sensen, Barbara, Kluge, Stefan, and Fischer, Marlene

Subjects
*ADULT respiratory distress syndrome, *INTENSIVE care units, *RESPIRATORY insufficiency, *ARTIFICIAL respiration, *CARBON dioxide
Abstract

Background: This study aimed to investigate the associations between dyscapnia, ventilatory variables, and mortality. We hypothesized that the association between mechanical power or ventilatory ratio and survival is mediated by dyscapnia. Methods: Patients with moderate or severe acute respiratory distress syndrome (ARDS), who received mechanical ventilation within the first 48 h after admission to the intensive care unit for at least 48 h, were included in this retrospective single-center study. Values of arterial carbon dioxide (PaCO2) were categorized into "hypercapnia" (PaCO2 ≥ 50 mm Hg), "normocapnia" (PaCO2 36-49 mmHg), and "hypocapnia" (PaCO2 ≤ 35 mm Hg). We used path analyses to assess the associations between ventilatory variables (mechanical power and ventilatory ratio) and mortality, where hypocapnia or hypercapnia were included as mediating variables. Results: Between December 2017 and April 2021, 435 patients were included. While there was a significant association between mechanical power and hypercapnia (BEM = 0.24 [95% CI: 0.15; 0.34], P <.01), there was no significant association between mechanical power or hypercapnia and ICU mortality. The association between mechanical power and intensive care unit (ICU) mortality was fully mediated by hypocapnia (BEM = −0.10 [95% CI: −0.19; 0.00], P =.05; BMO = 0.38 [95% CI: 0.13; 0.63], P <.01). Ventilatory ratio was significantly associated with hypercapnia (B = 0.23 [95% CI: 0.14; 0.32], P <.01). There was no significant association between ventilatory ratio, hypercapnia, and mortality. There was a significant effect of ventilatory ratio on mortality, which was fully mediated by hypocapnia (BEM = −0.14 [95% CI: −0.24; −0.05], P <.01; BMO = 0.37 [95% CI: 0.12; 0.62], P <.01). Conclusion: In mechanically ventilated patients with moderate or severe ARDS, the association between mechanical power and mortality was fully mediated by hypocapnia. Likewise, there was a mediating effect of hypocapnia on the association between ventilatory ratio and ICU mortality. Our results indicate that the debate on dyscapnia and outcome after ARDS should consider the impact of ventilatory variables. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Human Engineered Heart Tissue Patches Remuscularize the Injured Heart in a Dose-Dependent Manner

Author

Querdel, Eva, primary, Reinsch, Marina, additional, Castro, Liesa, additional, Köse, Deniz, additional, Bähr, Andrea, additional, Reich, Svenja, additional, Geertz, Birgit, additional, Ulmer, Bärbel, additional, Schulze, Mirja, additional, Lemoine, Marc D., additional, Krause, Tobias, additional, Lemme, Marta, additional, Sani, Jascha, additional, Shibamiya, Aya, additional, Stüdemann, Tim, additional, Köhne, Maria, additional, Bibra, Constantin von, additional, Hornaschewitz, Nadja, additional, Pecha, Simon, additional, Nejahsie, Yusuf, additional, Mannhardt, Ingra, additional, Christ, Torsten, additional, Reichenspurner, Hermann, additional, Hansen, Arne, additional, Klymiuk, Nikolai, additional, Krane, M., additional, Kupatt, C., additional, Eschenhagen, Thomas, additional, and Weinberger, Florian, additional

Published
2021
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9. The Bridge Occlusion Balloon for Venous Angioplasty in Superior Vena Cava Occlusion

Author

Pecha,Simon, Burger,Heiko, Castro,Liesa, Gosau,Nils, Atlihan,Gülsen, Willems,Stephan, Reichenspurner,Hermann, and Hakmi,Samer

Subjects
Superior Vena Cava, cardiovascular system, cardiovascular diseases, Bridge Occlusion Balloon, Venous Angioplasty
Abstract

The Bridge Occlusion Balloon is a compliant balloon, specifically designed for temporary Superior vena cava occlusion in case of Superior Vena Cava laceration during lead extraction procedures. We here report the first case, using Bridge Occlusion Ballon for a venous angioplasty in a patient with dysfunctional pacemaker leads and symptomatic Superior Vena Cava occlusion. After successful lead extraction, venography was showing a narrow venous canal. Therefore, venous angioplasty using the Bridge balloon was performed. Especially for high-risk lead extraction cases in patients with Superior Vena Cava stenosis, the Bridge Occlusion Ballon might be used as a combination of a safety-net in case of Superior Vena Cava perforation and for Superior Vena Cava angioplasty.

Published
2019

10. Impella 5.0 therapy as a bridge-to-decision option for patients on extracorporeal life support with unclear neurological outcomes

Author

Bernhardt, Alexander M, primary, Zipfel, Svante, additional, Reiter, Beate, additional, Hakmi, Samer, additional, Castro, Liesa, additional, Söffker, Gerold, additional, Kluge, Stefan, additional, Lubos, Edith, additional, Rybczinski, Meike, additional, Grahn, Hanno, additional, Schrage, Benedikt, additional, Becher, Peter Moritz, additional, Barten, Markus J, additional, Westermann, Dirk, additional, Blankenberg, Stefan, additional, and Reichenspurner, Hermann, additional

Published
2019
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13. Clinical frailty scale and outcome after coronary artery bypass grafting

Author

Reichart, Daniel, primary, Rosato, Stefano, additional, Nammas, Wail, additional, Onorati, Francesco, additional, Dalén, Magnus, additional, Castro, Liesa, additional, Gherli, Riccardo, additional, Gatti, Giuseppe, additional, Franzese, Ilaria, additional, Faggian, Giuseppe, additional, De Feo, Marisa, additional, Khodabandeh, Sorosh, additional, Santarpino, Giuseppe, additional, Rubino, Antonino S, additional, Maselli, Daniele, additional, Nardella, Saverio, additional, Salsano, Antonio, additional, Nicolini, Francesco, additional, Zanobini, Marco, additional, Saccocci, Matteo, additional, Bounader, Karl, additional, Kinnunen, Eeva-Maija, additional, Tauriainen, Tuomas, additional, Airaksinen, Juhani, additional, Seccareccia, Fulvia, additional, Mariscalco, Giovanni, additional, Ruggieri, Vito G, additional, Perrotti, Andrea, additional, and Biancari, Fausto, additional

Published
2018
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15. Navigation of lead extraction—is it possible? Impact of preprocedural electrocardiogram-triggered computed tomography on navigation of lead extraction†

Author

Vogler, Julia, primary, Pecha, Simon, additional, Azarrafiy, Ryan, additional, Castro, Liesa, additional, Deuschl, Florian, additional, Spink, Clemens, additional, Linder, Matthias, additional, von Hehn, Ulrike, additional, Willems, Stephan, additional, Reichenspurner, Hermann, additional, Gosau, Nils, additional, and Hakmi, Samer, additional

Published
2018
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18. Transcatheter valve-in-valve implantation versus redo surgical aortic valve replacement in patients with failed aortic bioprostheses

Author

Silaschi, Miriam, primary, Wendler, Olaf, additional, Seiffert, Moritz, additional, Castro, Liesa, additional, Lubos, Edith, additional, Schirmer, Johannes, additional, Blankenberg, Stefan, additional, Reichenspurner, Hermann, additional, Schäfer, Ulrich, additional, Treede, Hendrik, additional, MacCarthy, Philip, additional, and Conradi, Lenard, additional

Published
2016
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21. HEMODYNAMIC PERFORMANCE OF TRANSCATHETER HEART VALVES WITH SUPRA-ANNULAR OR INTRA-ANNULAR POSITION FOR TRANSCATHETER AORTIC VALVE-IN-VALVE IMPLANTATION

Author

Silaschi, Miriam, primary, Wendler, Olaf, additional, Seiffert, Moritz, additional, Castro, Liesa, additional, Schofer, Niklas, additional, Fink, Anna, additional, Reichenspurner, Hermann, additional, Blankenberg, Stefan, additional, MacCarthy, Philip, additional, Schaefer, Ulrich, additional, and Conradi, Lenard, additional

Published
2016
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22. Abstract 15174: Failing Aortic Tissue Valves in Patients at High Surgical Risk: Comparison of Outcomes After Transcatheter Aortic Valve-in-valve Procedures and Redo Surgical Aortic Valve Replacement

Author

Silaschi, Miriam, primary, Wendler, Olaf, additional, Castro, Liesa, additional, Seiffert, Moritz, additional, Lubos, Edith, additional, Blankenberg, Stefan, additional, Reichenspurner, Hermann, additional, Schäfer, Ulrich, additional, Treede, Hendrik, additional, MacCarthy, Philip, additional, and Conradi, Lenard, additional

Published
2015
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