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2. Sodium-glucose cotransporter-2 inhibitor therapy in kidney transplant patients with type 2 or post-transplant diabetes: an observational multicenter study

Author

Fructuoso, Ana I Sánchez, primary, Raba, Andrea Bedia, additional, Deras, Eduardo Banegas, additional, Sánchez, Luis A Vigara, additional, Cecilio, Rosalía Valero San, additional, Esteve, Antonio Franco, additional, Vega, Leonidas Cruzado, additional, Martínez, Eva Gavela, additional, Garcia, María E González, additional, Coronado, Pablo Saurdy, additional, Morales, Nancy D Valencia, additional, Larrondo, Sofía Zarraga, additional, Cano, Natalia Ridao, additional, Blanca, Auxiliadora Mazuecos, additional, Marrero, Domingo Hernández, additional, Castello, Isabel Beneyto, additional, Ramos, Javier Paul, additional, Ochoa, Adriana Sierra, additional, Molas, Carmen Facundo, additional, Roncero, Francisco González, additional, Ramírez, Armando Torres, additional, Guldris, Secundino Cigarrán, additional, and Flores, Isabel Pérez, additional

Published
2023
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4. Implementation of a National Priority Allocation System for Hypersensitized Patients in Spain, Based on Virtual Crossmatch: Initial Results

Author

Valentin, M.O., primary, Ruiz, J.C., additional, Vega, R., additional, Martín, C., additional, Matesanz, R., additional, Gimeno Lozano, Juan Jose, additional, Gutiérrez Dalmau, Alex, additional, Moreno Parado, Cristina, additional, Martín Moreno, Paloma Leticia, additional, Maside, Andrés Franco, additional, Perez Tamajón, Maria Lourdes, additional, Bosch Martínez, Alexandre, additional, Tagarro, Ernesto Fernández, additional, Hoyos, Marcos Lopez, additional, San Segundo, David, additional, Ruiz San Millán, Juan Carlos, additional, Colón, Mercedes Nocito, additional, Mendiluce Herrero, Alicia, additional, Marín Rubio, Luis Alberto, additional, Tabernero Fernández, Guadalupe, additional, Ontañón Rodríguez, Jesús, additional, Gonzalez, Inmaculada Lorenzo, additional, Canal, Cristina, additional, Pons, Jaume Martorell, additional, Diekmann, Fritz, additional, García Martínez, Anna, additional, Crespo Barrio, Marta, additional, Moreso Mateos, Francesc, additional, Bestard, Oriol, additional, Sole, Laura Cañas, additional, Alcaraz, Nieves Puig, additional, Castello, Isabel Beneyto, additional, Berga, Julia Kanter, additional, Roiz, Cristina Gonzalez, additional, Alcala Peña, M. Inmaculada, additional, Rial, Jose Gomez, additional, Rodríguez, Cándido Díaz, additional, Fernandez, Javier Cid, additional, Hernández, Angel Alonso, additional, García, Antón Fernández, additional, Pomar, Natalia Martinez, additional, Valeriano, Juan Rey, additional, Flores, Isabel Perez, additional, Castañer Alabaud, Jose Luis, additional, Fernández Rodríguez, Ana María, additional, Sierra, Esther Mancebo, additional, Belmonte, Amado Andrés, additional, Martín, Carlos Jiménez, additional, Melgar, Angel Alonso, additional, Gutierrez, Arantza Arrieta, additional, Erauzkin, Gorka Garcia, additional, Vázquez, Antonio Lopez, additional, Suarez Fernández, Maria Luisa, additional, Amador, Manuel Muro, additional, González Soriano, Maria José, additional, Pinto, Rocío Vega, additional, Delagebasala, Carmen Martín, additional, and Oliva Valentín Muñoz, María de la, additional

Published
2016
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5. Current preventive strategies and management of Epstein-Barr virus-related post-transplant lymphoproliferative disease in solid organ transplantation in Europe. Results of the ESGICH Questionnaire-based Cross-sectional Survey

Author

San-Juan, R., Manuel, O., Hirsch, H.H., Fernández-Ruiz, M., López-Medrano, F., Comoli, P., Caillard, S., Grossi, P., Aguado, J.M., Alamo-Martinez, Jose Maria, Anaya, Fernando, Anttila, Veli-Jukka, Arnol, Miha, Avolio, Alfonso W., Baccarani, Umberto, Castello, Isabel Beneyto, Boletis, Ioannis, Bonofiglio, Renzo, Bressollette, Celine, Brockmann, Jens, Caillard, Sophie, Pulido, Jorge Calvo, Catalan, Pilar, Christiansen, Claus, Cofan, Frederic, Cordero, Elisa, Leiro, Marisa Crespo, Dantal, Jacques, D'armini, Andrea, Delgado, Juan F., Strologo, Luca Dello, Raimondo, Francesco Di, Dierickx, Daan, Eis-Hübinger, Anna, Kremer, Samira Faf, Faggian, Giuseppe, Farinas, Maria Carmen, Folgueira, Maria Dolores, Fontana, Iris, Franco, Antonio, Furian, Lucrezia, Garzoni, Christian, Ghirardo, Giulia, Ginevri, Fabrizio, Grinyo, Josep, Grossi, Paolo Antonio, Gupte, Girish, Hansson, Lennart, Helantera, Ilkka, Herrero, Jose Ignacio, Hirsch, Hans H., Hobin, David, Hoffmann, Dieter, Jan, Lerut, Jarque, Isidro, Jespersen, Bente, Kaczmarek, Ingo, Kevin, Pilarczyk, Koneth, Irene, Kovac, Damjan, Lacaille, Florence, Lautenschlager, Irmeli, Len, Oscar, Llado, Laura, Loy, Monica, Manuel, Oriol, Marcos Maeso, Maria Angeles, Marianne, Leruez-Ville, Marsh, James, Meylan, Pascal, Minambres, Eduardo, Montejo, Miguel, Mueller, Nicolas, Munoz, Patricia, Nadalin, Silvio, Kamar, Nassim, Nicolas, Blin, Olivier, Detry, Palomo, Jesus, Pascual, Manuel, Peter, Jaksch, Pierre, Frange, Francisca Portero, M., Provot, Francois, Boluda, Esther Ramos, Regalia, Enrico, Reina, Gabriel, Reuter, Stefan, Ricart, Jose, Garcia, Minerva Rodriguez, Rollag, Halvor, Russo, Francesco Paolo, Sabe, Nuria, Salcedo, Magdalena, Santambrogio, Luigi, Seeman, Tomas, Serra, Nuria, Sgarabotto, Dino, Simonek, Jan, Thierry, Yandza, Thomsen, Marianne Kragh, Tihic, Nijaz, Torre-Cisneros, Julian, Travi, Giovanna, Tulissi, Patrizia, Moal, Valerie, Veroux, Massimiliano, Santandreu, Ana Vila, Vizzini, Giovanni, Zibar, Lada, San-Juan, R., Manuel, O., Hirsch, H.H., Fernández-Ruiz, M., López-Medrano, F., Comoli, P., Caillard, S., Grossi, P., Aguado, J.M., Alamo-Martinez, Jose Maria, Anaya, Fernando, Anttila, Veli-Jukka, Arnol, Miha, Avolio, Alfonso W., Baccarani, Umberto, Castello, Isabel Beneyto, Boletis, Ioannis, Bonofiglio, Renzo, Bressollette, Celine, Brockmann, Jens, Caillard, Sophie, Pulido, Jorge Calvo, Catalan, Pilar, Christiansen, Claus, Cofan, Frederic, Cordero, Elisa, Leiro, Marisa Crespo, Dantal, Jacques, D'armini, Andrea, Delgado, Juan F., Strologo, Luca Dello, Raimondo, Francesco Di, Dierickx, Daan, Eis-Hübinger, Anna, Kremer, Samira Faf, Faggian, Giuseppe, Farinas, Maria Carmen, Folgueira, Maria Dolores, Fontana, Iris, Franco, Antonio, Furian, Lucrezia, Garzoni, Christian, Ghirardo, Giulia, Ginevri, Fabrizio, Grinyo, Josep, Grossi, Paolo Antonio, Gupte, Girish, Hansson, Lennart, Helantera, Ilkka, Herrero, Jose Ignacio, Hirsch, Hans H., Hobin, David, Hoffmann, Dieter, Jan, Lerut, Jarque, Isidro, Jespersen, Bente, Kaczmarek, Ingo, Kevin, Pilarczyk, Koneth, Irene, Kovac, Damjan, Lacaille, Florence, Lautenschlager, Irmeli, Len, Oscar, Llado, Laura, Loy, Monica, Manuel, Oriol, Marcos Maeso, Maria Angeles, Marianne, Leruez-Ville, Marsh, James, Meylan, Pascal, Minambres, Eduardo, Montejo, Miguel, Mueller, Nicolas, Munoz, Patricia, Nadalin, Silvio, Kamar, Nassim, Nicolas, Blin, Olivier, Detry, Palomo, Jesus, Pascual, Manuel, Peter, Jaksch, Pierre, Frange, Francisca Portero, M., Provot, Francois, Boluda, Esther Ramos, Regalia, Enrico, Reina, Gabriel, Reuter, Stefan, Ricart, Jose, Garcia, Minerva Rodriguez, Rollag, Halvor, Russo, Francesco Paolo, Sabe, Nuria, Salcedo, Magdalena, Santambrogio, Luigi, Seeman, Tomas, Serra, Nuria, Sgarabotto, Dino, Simonek, Jan, Thierry, Yandza, Thomsen, Marianne Kragh, Tihic, Nijaz, Torre-Cisneros, Julian, Travi, Giovanna, Tulissi, Patrizia, Moal, Valerie, Veroux, Massimiliano, Santandreu, Ana Vila, Vizzini, Giovanni, and Zibar, Lada

Abstract

There is limited clinical evidence on the utility of the monitoring of Epstein-Barr virus (EBV) DNAemia in the pre-emptive management of post-transplant lymphoproliferative disease (PTLD) in solid organ transplant (SOT) recipients. We investigated current preventive measures against EBV-related PTLD through a web-based questionnaire sent to 669 SOT programmes in 35 European countries. This study was performed on behalf of the ESGICH study group from the European Society of Clinical Microbiology and Infectious Diseases. A total of 71 SOT programmes from 15 European countries participated in the study. EBV serostatus of the recipient is routinely obtained in 69/71 centres (97%) and 64 (90%) have access to EBV DNAemia assays. EBV monitoring is routinely used in 85.9% of the programmes and 77.4% reported performing pre-emptive treatment for patients with significant EBV DNAemia levels. Pre-emptive treatment for EBV DNAemia included reduction of immunosuppression in 50.9%, switch to mammalian target of rapamycin inhibitors in 30.9%, and use of rituximab in 14.5% of programmes. Imaging by whole-body 18-fluoro-deoxyglucose positron emission tomography (FDG-PET) is used in 60.9% of centres to rule out PTLD and complemented computer tomography is used in 50%. In 10.9% of centres, FDG-PET is included in the first-line diagnostic workup in patients with high-risk EBV DNAemia. Despite the lack of definitive evidence, EBV load measurements are frequently used in Europe to guide diagnostic workup and pre-emptive reduction of immunosuppression. We need prospective and controlled studies to define the impact of EBV monitoring in reducing the risk of PTLD in SOT recipients.

Published
2015

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