37 results on '"Cassimatis M"'
Search Results
2. Post-Concussion Clinical Insomnia is Associated with Heightened Symptom Severity, Lower Cognitive Function and Delayed Recovery Duration in Children and Adolescents
- Author
-
Cassimatis, M., primary, Orr, R., additional, Fyffe, A., additional, and Browne, G., additional
- Published
- 2023
- Full Text
- View/download PDF
3. The Relationship Between Post-Concussion Exercise Tolerance, Symptom Burden and Recovery Duration in Paediatric Patients: An 8-Year Longitudinal Study
- Author
-
Cassimatis, M., primary, Orr, R., additional, Fyffe, A., additional, and Browne, G., additional
- Published
- 2023
- Full Text
- View/download PDF
4. Mental Health Symptoms Following concussion in Children and Adolescents
- Author
-
Yau, Y., primary, Orr, R., additional, Fyffe, A., additional, Cassimatis, M., additional, and Browne, G., additional
- Published
- 2022
- Full Text
- View/download PDF
5. Greater symptom burden results in reduced exercise tolerance in children and adolescents following concussion
- Author
-
Browne, G., primary, Carron, M., additional, Cassimatis, M., additional, Fyffe, A., additional, and Orr, R., additional
- Published
- 2021
- Full Text
- View/download PDF
6. The use of melatonin for sleep disturbance following traumatic brain injury: A systematic review
- Author
-
Cassimatis, M., primary, Browne, G., additional, and Orr, R., additional
- Published
- 2021
- Full Text
- View/download PDF
7. The concussed female athlete
- Author
-
Browne, G., primary, Cassimatis, M., additional, Fyffe, A., additional, and Orr, R., additional
- Published
- 2021
- Full Text
- View/download PDF
8. Visual snow syndrome: An important consideration in the adolescent with persisting headache and concussion symptoms
- Author
-
Browne, G., primary, Cassimatis, M., additional, Fyffe, A., additional, and Orr, R., additional
- Published
- 2021
- Full Text
- View/download PDF
9. Injury patterns of concussion/mild traumatic brain injury in children presenting to a major Australian paediatic trauma centre
- Author
-
Browne, G., primary, Cassimatis, M., additional, Fyffe, A., additional, and Orr, R., additional
- Published
- 2021
- Full Text
- View/download PDF
10. Early injury evaluation following concussion is associated with improved recovery time in children and adolescents
- Author
-
Cassimatis, M., primary, Orr, R., additional, Fyffe, A., additional, and Browne, G., additional
- Published
- 2021
- Full Text
- View/download PDF
11. Using digital interventions to improve the cardiometabolic health of populations: Ameta-review of reporting quality
- Author
-
O'Neil, Adrienne, Cocker, F, Rarau, P, Baptista, S, Cassimatis, M, Taylor, CB, Lau, AYS, Kanuri, N, Oldenburg, B, O'Neil, Adrienne, Cocker, F, Rarau, P, Baptista, S, Cassimatis, M, Taylor, CB, Lau, AYS, Kanuri, N, and Oldenburg, B
- Abstract
Objectives. We conducted a meta-review to determine the reporting quality of user-centered digital interventions for the prevention and management of cardiometabolic conditions. Materials and Methods. Using predetermined inclusion criteria, systematic reviews published between 2010 and 2015 were identified from 3 databases. To assess whether current evidence is sufficient to inform wider uptake and implementation of digital health programs, we assessed the quality of reporting of research findings using (1) endorsement of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, (2) a quality assessment framework (eg, Cochrane risk of bias assessment tool), and (3) 8 parameters of the Consolidated Standards of Reporting Trials of Electronic and Mobile HEalth Applications and onLine TeleHealth (CONSORT-eHEALTH) guidelines (developed in 2010). Results. Of the 33 systematic reviews covering social media, Web-based programs, mobile health programs, and compositemodalities, 6 reported using the recommended PRISMAguidelines. Seven did not report using a quality assessment framework. Applying the CONSORT-EHEALTH guidelines, reportingwas ofmild tomoderate strength. Discussion. To our knowledge, this is the first meta-review to provide a comprehensive analysis of the quality of reporting of research findings for a range of digital health interventions. Our findings suggest that the evidence base and quality of reporting in this rapidly developing field needs significant improvement in order to inform wider implementation and uptake. Conclusion. The inconsistent quality of reporting of digital health interventions for cardiometabolic outcomes may be a critical impediment to real-world implementation.
- Published
- 2017
12. Modifying lifestyle behaviours to improve the prevention and management of cardiovascular disease
- Author
-
Alvarenga, ME, Byrne, D, O'Neil, A, Oldenburg, B, Baptista, S, Cassimatis, M, COCKER, F, Alvarenga, ME, Byrne, D, O'Neil, A, Oldenburg, B, Baptista, S, Cassimatis, M, and COCKER, F
- Abstract
This handbook brings together the full weight of contemporary evidence bearing on what is now commonly termed “psycho-cardiology”.
- Published
- 2017
13. A systematic review of geographical differences in management and outcomes for colorectal cancer in Australia.
- Author
-
Ireland, MJ, March, S, Crawford-Williams, F, Cassimatis, M, Aitken, JF, Hyde, MK, Chambers, SK, Sun, J, Dunn, J, Ireland, MJ, March, S, Crawford-Williams, F, Cassimatis, M, Aitken, JF, Hyde, MK, Chambers, SK, Sun, J, and Dunn, J
- Abstract
BACKGROUND: Australia and New Zealand have the highest incidence of colorectal cancer (CRC) in the world, presenting considerable health, economic, and societal burden. Over a third of the Australian population live in regional areas and research has shown they experience a range of health disadvantages that result in a higher disease burden and lower life expectancy. The extent to which geographical disparities exist in CRC management and outcomes has not been systematically explored. The present review aims to identify the nature of geographical disparities in CRC survival, clinical management, and psychosocial outcomes. METHODS: The review followed PRISMA guidelines and searches were undertaken using seven databases covering articles between 1 January 1990 and 20 April 2016 in an Australian setting. Inclusion criteria stipulated studies had to be peer-reviewed, in English, reporting data from Australia on CRC patients and relevant to one of fourteen questions examining geographical variations in a) survival outcomes, b) patient and cancer characteristics, c) diagnostic and treatment characteristics and d) psychosocial and quality of life outcomes. RESULTS: Thirty-eight quantitative, two qualitative, and three mixed-methods studies met review criteria. Twenty-seven studies were of high quality, sixteen studies were of moderate quality, and no studies were found to be low quality. Individuals with CRC living in regional, rural, and remote areas of Australia showed poorer survival and experienced less optimal clinical management. However, this effect is likely moderated by a range of other factors (e.g., SES, age, gender) and did appear to vary linearly with increasing distance from metropolitan centres. No studies examined differences in use of stoma, or support with stomas, by geographic location. CONCLUSIONS: Overall, despite evidence of disparity in CRC survival and clinical management across geographic locations, the evidence was limited and at times inconsiste
- Published
- 2017
14. My Diabetes Coach User Guide
- Author
-
O'NEIL, A, Baptista, S, Bird, D, Cassimatis, M, Cocker, F, Oldenburg, B, O'NEIL, A, Baptista, S, Bird, D, Cassimatis, M, Cocker, F, and Oldenburg, B
- Published
- 2016
15. IMPROVING THE QUALITY AND REPORTING OF EVIDENCE FOR DIGITAL HEALTH INTERVENTIONS FOR MAXIMUM POPULATION-LEVEL IMPACT: A META-REVIEW
- Author
-
O'Neil, A, Cocker, F, Rarau, P, Baptista, S, Cassimatis, M, Taylor, B, Lau, A, Kanuri, N, Oldenburg, B, O'Neil, A, Cocker, F, Rarau, P, Baptista, S, Cassimatis, M, Taylor, B, Lau, A, Kanuri, N, and Oldenburg, B
- Published
- 2016
16. Les transformations des paysages agricoles de la Ligurie: quelques exemples significatifs
- Author
-
Brandolini, Pierluigi, Cassimatis, M., Cevasco, A., Gavinelli, D., Pappalardo, M., Rollando, A., Spotorno, Mauro, and Terranova, R.
- Published
- 2005
17. Randomised controlled trial of an automated, interactive telephone intervention to improve type 2 diabetes self-management (Telephone-Linked Care Diabetes Project): study protocol
- Author
-
Bird, D, Oldenburg, B, Cassimatis, M, Russell, A, Ash, S, Courtney, MD, Scuffham, PA, Stewart, I, Wootton, R, Friedman, RH, Bird, D, Oldenburg, B, Cassimatis, M, Russell, A, Ash, S, Courtney, MD, Scuffham, PA, Stewart, I, Wootton, R, and Friedman, RH
- Abstract
BACKGROUND: An estimated 285 million people worldwide have diabetes and its prevalence is predicted to increase to 439 million by 2030. For the year 2010, it is estimated that 3.96 million excess deaths in the age group 20-79 years are attributable to diabetes around the world. Self-management is recognised as an integral part of diabetes care. This paper describes the protocol of a randomised controlled trial of an automated interactive telephone system aiming to improve the uptake and maintenance of essential diabetes self-management behaviours. METHODS/DESIGN: A total of 340 individuals with type 2 diabetes will be randomised, either to the routine care arm, or to the intervention arm in which participants receive the Telephone-Linked Care (TLC) Diabetes program in addition to their routine care. The intervention requires the participants to telephone the TLC Diabetes phone system weekly for 6 months. They receive the study handbook and a glucose meter linked to a data uploading device. The TLC system consists of a computer with software designed to provide monitoring, tailored feedback and education on key aspects of diabetes self-management, based on answers voiced or entered during the current or previous conversations. Data collection is conducted at baseline (Time 1), 6-month follow-up (Time 2), and 12-month follow-up (Time 3). The primary outcomes are glycaemic control (HbA1c) and quality of life (Short Form-36 Health Survey version 2). Secondary outcomes include anthropometric measures, blood pressure, blood lipid profile, psychosocial measures as well as measures of diet, physical activity, blood glucose monitoring, foot care and medication taking. Information on utilisation of healthcare services including hospital admissions, medication use and costs is collected. An economic evaluation is also planned. DISCUSSION: Outcomes will provide evidence concerning the efficacy of a telephone-linked care intervention for self-management of diabetes. Furthermore
- Published
- 2010
18. Morfologia ed evoluzione recente della fascia costiera tra Capo Berta e Capo Cervo (Liguria occidentale)
- Author
-
Biancotti, A, Brandolini, Pierluigi, Cassimatis, M, Firpo, Marco, Massaglia, L, Piccazzo, Mauro, and Terranova, R.
- Published
- 1996
19. La Val Fontanabuona in Liguria; studio preliminare per un progetto di valorizzazione delle risorse agrarie
- Author
-
Cassimatis, M., Cevasco, A., and Pappalardo, Marta
- Published
- 1994
20. Randomised controlled trial of an automated, interactive telephone intervention to improve type 2 diabetes self-management (Telephone-Linked Care Diabetes Project): study protocol
- Author
-
Scuffham Paul A, Courtney Mary D, Ash Susan, Russell Anthony, Cassimatis Mandy, Oldenburg Brian, Bird Dominique, Stewart Ian, Wootton Richard, and Friedman Robert H
- Subjects
Public aspects of medicine ,RA1-1270 - Abstract
Abstract Background An estimated 285 million people worldwide have diabetes and its prevalence is predicted to increase to 439 million by 2030. For the year 2010, it is estimated that 3.96 million excess deaths in the age group 20-79 years are attributable to diabetes around the world. Self-management is recognised as an integral part of diabetes care. This paper describes the protocol of a randomised controlled trial of an automated interactive telephone system aiming to improve the uptake and maintenance of essential diabetes self-management behaviours. Methods/Design A total of 340 individuals with type 2 diabetes will be randomised, either to the routine care arm, or to the intervention arm in which participants receive the Telephone-Linked Care (TLC) Diabetes program in addition to their routine care. The intervention requires the participants to telephone the TLC Diabetes phone system weekly for 6 months. They receive the study handbook and a glucose meter linked to a data uploading device. The TLC system consists of a computer with software designed to provide monitoring, tailored feedback and education on key aspects of diabetes self-management, based on answers voiced or entered during the current or previous conversations. Data collection is conducted at baseline (Time 1), 6-month follow-up (Time 2), and 12-month follow-up (Time 3). The primary outcomes are glycaemic control (HbA1c) and quality of life (Short Form-36 Health Survey version 2). Secondary outcomes include anthropometric measures, blood pressure, blood lipid profile, psychosocial measures as well as measures of diet, physical activity, blood glucose monitoring, foot care and medication taking. Information on utilisation of healthcare services including hospital admissions, medication use and costs is collected. An economic evaluation is also planned. Discussion Outcomes will provide evidence concerning the efficacy of a telephone-linked care intervention for self-management of diabetes. Furthermore, the study will provide insight into the potential for more widespread uptake of automated telehealth interventions, globally. Trial Registration Number ACTRN12607000594426
- Published
- 2010
- Full Text
- View/download PDF
21. Using an integrated social cognition model to identify the determinants of QR code check-in compliance behaviors in the COVID-19 pandemic.
- Author
-
Mac TN, Phipps DJ, Parkinson J, Cassimatis M, and Hamilton K
- Subjects
- Humans, Female, Male, Adult, Queensland, Intention, Middle Aged, SARS-CoV-2, Victoria, Models, Psychological, Pandemics, COVID-19 psychology, Social Cognition
- Abstract
In Australia, checking in while entering venues was a legal requirement during the COVID-19 pandemic to track potential infection sites. This two-wave correlational study used an integrated theory of planned behavior model including moral norms, anticipated regret, and habit to predict check-in compliance in a sample of 181 Victorians (Mean Age = 41.88, 56.4% female) and 162 Queenslanders (Mean Age = 43.26, 47.5% female). Habit and intention predicted behavior, while perceived behavioral control did not. Intention was predicted by baseline habit, attitude, subjective norm, and moral norm in the Victorian sample, while only baseline habit and moral norm predicted intention in the Queensland sample. This study has potential implications for reviewing previous strategies and for future pandemic preparedness, both by identifying the drivers of infection control compliance, and through the discussion of how differences in effects between states may be linked to each state's experience of the pandemic (e.g. infection rates, lockdown length)., Competing Interests: Declaration of conflicting interestsThe authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.
- Published
- 2024
- Full Text
- View/download PDF
22. Perspectives of people with myasthenia gravis on physical activity and experience of physical activity advice from health professionals in the Australian context: a qualitative study.
- Author
-
Alsop T, Cassimatis M, Williams KL, and Gomersall SR
- Abstract
Purpose: Physical activity is an important modifiable determinant of health. There has been a historical aversion to movement in people with myasthenia gravis (MG) due to the pathophysiology of the disease, however, research suggests engagement in physical activity is safe and does not exacerbate symptoms. There are currently no studies investigating the qualitative perspectives of people with MG on physical activity. The aim of this study was to explore perceptions of physical activity, barriers, enablers, and participants' experiences of physical activity advice from health professionals., Materials and Methods: Semi-structured interviews were used, with verbatim transcripts analysed using content analysis., Results: Ten adults (median age 64.5 years) living in Australia with generalised MG were interviewed. Key findings were identified: (1) Physical activity is perceived to be important for general health and for MG; (2) Medical management and social support are key enablers; (3) Fatigue and pain are potential barriers; and (4) Experiences with healthcare professionals were considered insufficient and failed to provide disease specific advice regarding MG and physical activity., Conclusion: People with MG have unique barriers and enablers to physical activity engagement that clinicians should consider when providing physical activity behaviour change support to this population.
- Published
- 2024
- Full Text
- View/download PDF
23. Children and exercise.
- Author
-
Fyffe A, Orr R, Cassimatis M, and Browne G
- Subjects
- Adolescent, Humans, Child, Australia, Exercise Therapy, Exercise, General Practitioners
- Abstract
Background: Exercise is widely understood to improve health outcomes in children and adolescents and to contribute to the prevention and management of many chronic conditions. Australian children are not currently meeting the recommended physical activity guidelines, and these habits are likely to extend into adulthood without intervention., Objective: The aim of this paper is to provide general practitioners (GPs) with the tools to perform a basic exercise assessment with children and adolescents and an understanding of the core principles of exercise prescription for general and special paediatric populations., Discussion: GPs are limited by time often precluding the assessment of exercise levels in children and adolescents unless it is immediately relevant to their presentation. This article discusses simple methods of assessing physical activity, the importance of appropriately prescribed exercise and its benefits for physical, psychological and social health and wellbeing.
- Published
- 2024
- Full Text
- View/download PDF
24. Exercise and Musculoskeletal Health in Men With Low Bone Mineral Density: A Systematic Review.
- Author
-
Hu K, Cassimatis M, and Girgis C
- Abstract
Objective: This systematic review aims to determine the effects of exercise on bone and muscle health in men with low bone density., Data Sources: An electronic search in the following databases was performed: Medline, AMED, Embase, Scopus, and SPORTDiscus between January 1940 and September 2021., Study Selection: Randomized or non-randomized trials involving any form of exercise in adult men with a densitometric diagnosis of osteoporosis or osteopenia and reported outcomes relating to bone or muscle health. Two independent reviewers screened 12,018 records, resulting in 13 eligible articles., Data Extraction: One reviewer extracted data into a pre-formed table, including characteristics of the exercise intervention, population examined, and primary and secondary outcomes. Study quality was assessed by 2 independent reviewers using the Tool for assEssment of Study qualiTy and reporting in Exercise (TESTEX)., Data Synthesis: Thirteen publications, originating from 6 unique trials, were eligible for inclusion, which assessed the effect of resistance training, impact training, whole body vibration, and traditional Chinese exercises. Resistance training was the most effective: it stimulates the replacement of adipose tissue with muscle, and in some cases, improved bone density., Conclusions: Exercise, especially resistance training, slowed down the natural progression of osteoporosis and sarcopenia in men. These benefits are reflected in enhancements to function, such as improved mobility and balance. Other exercise modalities, such as whole body vibration and traditional Chinese exercises, generated minimal improvements to bone health, strength, and balance., (© 2023 The Authors.)
- Published
- 2023
- Full Text
- View/download PDF
25. Association of Sleep Disturbance With Neurocognition, Symptom Severity, and Recovery in Pediatric Concussion: A 10-Year Retrospective Analysis of a Tertiary Referral Concussion Clinic.
- Author
-
Cassimatis M, Orr R, Fyffe A, and Browne G
- Subjects
- Adolescent, Humans, Male, Child, Female, Retrospective Studies, Cross-Sectional Studies, Neuropsychological Tests, Sleep, Memory Disorders diagnosis, Memory Disorders etiology, Referral and Consultation, Brain Concussion complications, Brain Concussion diagnosis, Athletic Injuries diagnosis, Post-Concussion Syndrome psychology, Sleep Wake Disorders diagnosis, Sleep Wake Disorders etiology
- Abstract
Objectives: To investigate the relationship between sleep disturbance, neurocognition, symptom severity, and recovery in children and adolescents with concussion. Sex-related comparisons were also examined., Setting: Pediatric tertiary referral concussion clinic., Participants: Children and adolescents (aged 6-18 years; n = 554) diagnosed with concussion., Design: Cross-sectional retrospective study., Main Measures: Assessment data were obtained from Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) Applications. Sleep disturbance was quantified using the sleep-related domains of the Post-Concussion Symptom Scale (PCSS) and self-report sleep duration. Sleep duration was categorized as short (<7 hours), intermediate (7-9 hours), and long (≥9 hours). Outcome measures included neurocognition, measured via composite scores of ImPACT cognitive domains (verbal memory, visual memory, visual motor speed, reaction time); symptom severity, using the PCSS; and concussion recovery time (days)., Results: Short sleep resulted in significantly poorer verbal memory ( P = .03), visual memory ( P = .02), and reaction time ( P = .01). Sleep disturbance was strongly associated with total symptom burden (ρ = 0.90, P < .001). Recovery time, median (interquartile range), was significantly prolonged with short sleep, 61 (30-136) days, compared with intermediate, 38 (21-72) days, and long, 34 (19-71) days, sleep ( P < .001). Overall, female participants demonstrated significantly longer recovery times than male participants (mean 91 ± 95 vs 58 ± 85 days, P < .001). Females exhibited similar concussion recovery times irrespective of reported sleep duration ( P = .95), whereas mean recovery time in males was significantly longer with short sleep (84 ± 82 days) than with intermediate (61 ± 106 days) and long (49 ± 62 days) sleep ( P < .001)., Conclusion: Sleep disturbance following concussion poses as a promising modifiable risk factor to alleviate postinjury impairments, including cognitive deficits and symptom burden. Female children were found to experience more severe concussion symptoms and protracted recovery times than their male counterparts. Investigations into the factors that may contribute to sex-related differences following concussion are warranted., Competing Interests: The authors declare no conflicts of interest., (Copyright © 2022 Wolters Kluwer Health, Inc. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
26. Ethnic determinants of skeletal health in female patients with fragility fracture in a culturally diverse population.
- Author
-
Hu K, Cassimatis M, Nguyen M, and Girgis CM
- Abstract
Background: Low bone density leads to fragility fracture, with significant impact on morbidity and mortality. While ethnic differences in bone density have been observed in healthy subjects, this has not yet been explored in fragility fracture patients., Aims: To assess if ethnicity is associated with bone mineral density and serum markers of bone health in female patients who experience fragility fractures., Methods: 219 female patients presenting with at least one fragility fracture at a major tertiary hospital in Western Sydney Australia were studied. Western Sydney is a region with great cultural diversity, comprising people from over 170 ethnicities. Within this cohort, the three largest broad ethnic groups were Caucasians (62.1 %), Asians (22.8 %), and Middle Eastern patients (15.1 %). Location and nature of the presenting fracture and other relevant past medical history were obtained. Bone mineral density, measured by dual-energy X-ray absorptiometry, and bone-related serum markers were compared between ethnicities. Covariates (age, height, weight, diabetes, smoking, and at-risk drinking) were adjusted in multiple linear regression model., Results: Although Asian ethnicity was associated with lower bone mineral density at the lumbar spine in fragility fracture patients, this association was no longer significant after adjustment for weight. Ethnicity (Asian or Middle Eastern) was not a determinant of bone mineral density at any other skeletal site. Caucasians had lower estimated glomerular filtration rate compared to Asian and Middle Eastern subjects. Serum parathyroid hormone concentrations were significantly lower in Asians compared to other ethnicities., Conclusion: Asian ethnicity and Middle Eastern ethnicity were not major determinants of bone mineral density at the lumbar spine, femoral neck, or total hip., Competing Interests: All authors declare no conflict of interests., (© 2023 The Authors.)
- Published
- 2023
- Full Text
- View/download PDF
27. The Utility of Melatonin for the Treatment of Sleep Disturbance After Traumatic Brain Injury: A Scoping Review.
- Author
-
Cassimatis M, Browne G, and Orr R
- Subjects
- Adolescent, Adult, Humans, Young Adult, Anxiety, Sleep, Brain Injuries, Traumatic complications, Brain Injuries, Traumatic drug therapy, Melatonin therapeutic use, Melatonin pharmacology, Sleep Wake Disorders drug therapy, Sleep Wake Disorders etiology
- Abstract
Objective: To investigate the utility of melatonin supplementation as a treatment option for individuals with sleep disturbance after traumatic brain injury (TBI)., Data Sources: A systematic search was conducted in 6 electronic databases (Medline, AMED, CINAHL, Embase, Scopus, and SPORTDiscus) from earliest records to April 2022., Study Selection: Studies were eligible for inclusion if they met the following criteria: a) human participants with sleep disturbance after TBI, b) melatonin or melatonergic agent used as an intervention to treat sleep disturbance, and c) outcomes of melatonin administration reported. All TBI severity types (mild, moderate, and severe) were eligible. The initial search retrieved a total of 595 articles, with 9 studies meeting the eligibility criteria., Data Extraction: Two reviewers independently extracted data from eligible studies and assessed methodological quality. Extracted data consisted of participant and injury characteristics, melatonin interventional properties, and sleep outcome. Methodological quality was assessed via the Downs and Black checklist., Data Synthesis: A total of 251 participants with TBI-induced sleep disturbance (mean age range: 14.0-42.5 years) were included. Melatonin, Circadin (prolonged-release melatonin), or Ramelteon (melatonin receptor agonist) were administered. Dosages and intervention duration ranged from 2 to 10 mg and 3 to 12 weeks, respectively. Eight out of 9 studies reported positive outcomes after melatonin treatment. Significant improvements in subjective sleep quality, objective sleep efficiency, and total sleep time were found with melatonin. Reductions in self-reported fatigue, anxiety, and depressive symptoms were also observed with melatonin treatment. No serious adverse events were reported after melatonin administration., Conclusion: Melatonin has good tolerability after short-term use and the potential to be a therapeutic agent for those with sleep disturbance after TBI. Melatonin was shown to be beneficial to sleep quality, sleep duration, and sleep efficiency. Additional clinically relevant outcomes of improved mental health suggest that melatonin use may be a promising treatment option for individuals experiencing co-occurring disorders of mood and sleep disturbance post-injury., (Copyright © 2022 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.)
- Published
- 2023
- Full Text
- View/download PDF
28. Greater symptom burden results in reduced exercise tolerance in adolescents following concussion.
- Author
-
Fyffe A, Carron MA, Orr R, Cassimatis M, and Browne G
- Subjects
- Adolescent, Exercise Tolerance, Female, Humans, Male, Retrospective Studies, Athletic Injuries diagnosis, Brain Concussion complications, Brain Concussion diagnosis, Post-Concussion Syndrome diagnosis, Post-Concussion Syndrome etiology
- Abstract
Objectives: To explore the relationship between symptoms and exercise tolerance in adolescents following concussion., Methods: A retrospective analysis of 417 adolescents who attended a concussion service between January 2015 and April 2021 was performed, with 149 meeting eligibility criteria for inclusion. Post-Concussion Symptom Scale (PCSS) and graded exercise tolerance time (min) were assessed at initial and follow-up visits. Spearman's correlation was used to examine the relationship between PCSS scores and exercise time., Results: Adolescents (n = 149, 13.9 ± 1.7 years, 66.4% male) presented at 28.6 ± 19.7 days post-injury. Statistically significant correlations were identified between initial (r = -0.36, p < .001) and follow-up (r = -0.41, p < .001) PCSS scores and exercise time among all participants. Initial PCSS and initial exercise time were inversely correlated for males (r = -0.24, p = .018) and females (r = -0.22, p = .127). Follow-up PCSS and follow-up exercise time were inversely correlated for males (r = -0.30, p = .003) and females (r = -0.35, p = .014)., Conclusion: There is a statistically significant relationship between higher PCSS and poorer exercise time and both factors should be considered together to provide the most accurate assessment, particularly in females.
- Published
- 2022
- Full Text
- View/download PDF
29. A Decade in Review: A Systematic Review of Virtual Reality Interventions for Emotional Disorders.
- Author
-
Rowland DP, Casey LM, Ganapathy A, Cassimatis M, and Clough BA
- Abstract
Research is increasingly demonstrating the therapeutic benefits of virtual reality interventions for various mental health conditions, though these rarely translate from research to application in clinical settings. This systematic review aims to examine the efficacy of current virtual reality interventions for emotional disorders, with a focus on clinical and technological features that influence translation of treatments from research to clinical practice. A comprehensive systematic literature search was conducted following PRISMA guidelines, for studies including the application of a virtual reality intervention to a clinical population of adults with an emotional disorder. Thirty-seven eligible studies were identified, appraised, and assessed for bias. Treatment effects were typically large across studies, with virtual reality being considered an efficacious treatment modality for various anxiety disorders and post-traumatic stress disorder. Virtual reality interventions were typically used for delivering exposure in cognitive behavioural therapy approaches. Considerable variability was seen in cost, technological specifications, degree of therapist involvement, delivery format, dosage, duration, and frequency of treatment. Suboptimal methodological rigour was identified in some studies. Remote use of virtual reality was rare, despite increasing options for in home use. Virtual reality interventions have the potential to overcome barriers to care and better meet the needs of consumers. Future research should examine the efficacy of virtual reality for treatment of depressive disorders and obsesive compulsive disorder. Improved methodological reporting and development of transdiagnostic and remotely delivered virtual reality interventions, will likely increase the translation of this treatment modality., Competing Interests: Conflict of Interest: The authors of this article declare no conflict of interest., (Copyright © 2022, Colegio Oficial de la Psicología de Madrid.)
- Published
- 2022
- Full Text
- View/download PDF
30. Using digital interventions to improve the cardiometabolic health of populations: a meta-review of reporting quality.
- Author
-
O'Neil A, Cocker F, Rarau P, Baptista S, Cassimatis M, Barr Taylor C, Lau AYS, Kanuri N, and Oldenburg B
- Subjects
- Humans, Social Media, Cardiovascular Diseases therapy, Diabetes Mellitus, Type 2 therapy, Health Promotion methods, Mobile Applications, Telemedicine
- Abstract
Objectives: We conducted a meta-review to determine the reporting quality of user-centered digital interventions for the prevention and management of cardiometabolic conditions., Materials and Methods: Using predetermined inclusion criteria, systematic reviews published between 2010 and 2015 were identified from 3 databases. To assess whether current evidence is sufficient to inform wider uptake and implementation of digital health programs, we assessed the quality of reporting of research findings using (1) endorsement of the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines, (2) a quality assessment framework (eg, Cochrane risk of bias assessment tool), and (3) 8 parameters of the Consolidated Standards of Reporting Trials of Electronic and Mobile HEalth Applications and onLine TeleHealth (CONSORT-eHEALTH) guidelines (developed in 2010)., Results: Of the 33 systematic reviews covering social media, Web-based programs, mobile health programs, and composite modalities, 6 reported using the recommended PRISMA guidelines. Seven did not report using a quality assessment framework. Applying the CONSORT-EHEALTH guidelines, reporting was of mild to moderate strength., Discussion: To our knowledge, this is the first meta-review to provide a comprehensive analysis of the quality of reporting of research findings for a range of digital health interventions. Our findings suggest that the evidence base and quality of reporting in this rapidly developing field needs significant improvement in order to inform wider implementation and uptake., Conclusion: The inconsistent quality of reporting of digital health interventions for cardiometabolic outcomes may be a critical impediment to real-world implementation., (© The Author 2017. Published by Oxford University Press on behalf of the American Medical Informatics Association. All rights reserved. For Permissions, please email: journals.permissions@oup.com.)
- Published
- 2017
- Full Text
- View/download PDF
31. A systematic review of geographical differences in management and outcomes for colorectal cancer in Australia.
- Author
-
Ireland MJ, March S, Crawford-Williams F, Cassimatis M, Aitken JF, Hyde MK, Chambers SK, Sun J, and Dunn J
- Subjects
- Australia epidemiology, Female, Humans, Incidence, Male, Qualitative Research, Quality of Life, Rural Population, Survival Analysis, Colorectal Neoplasms epidemiology, Healthcare Disparities
- Abstract
Background: Australia and New Zealand have the highest incidence of colorectal cancer (CRC) in the world, presenting considerable health, economic, and societal burden. Over a third of the Australian population live in regional areas and research has shown they experience a range of health disadvantages that result in a higher disease burden and lower life expectancy. The extent to which geographical disparities exist in CRC management and outcomes has not been systematically explored. The present review aims to identify the nature of geographical disparities in CRC survival, clinical management, and psychosocial outcomes., Methods: The review followed PRISMA guidelines and searches were undertaken using seven databases covering articles between 1 January 1990 and 20 April 2016 in an Australian setting. Inclusion criteria stipulated studies had to be peer-reviewed, in English, reporting data from Australia on CRC patients and relevant to one of fourteen questions examining geographical variations in a) survival outcomes, b) patient and cancer characteristics, c) diagnostic and treatment characteristics and d) psychosocial and quality of life outcomes., Results: Thirty-eight quantitative, two qualitative, and three mixed-methods studies met review criteria. Twenty-seven studies were of high quality, sixteen studies were of moderate quality, and no studies were found to be low quality. Individuals with CRC living in regional, rural, and remote areas of Australia showed poorer survival and experienced less optimal clinical management. However, this effect is likely moderated by a range of other factors (e.g., SES, age, gender) and did appear to vary linearly with increasing distance from metropolitan centres. No studies examined differences in use of stoma, or support with stomas, by geographic location., Conclusions: Overall, despite evidence of disparity in CRC survival and clinical management across geographic locations, the evidence was limited and at times inconsistent. Further, access to treatment and services may not be the main driver of disparities, with individual patient characteristics and type of region also playing an important role. A better understanding of factors driving ongoing and significant geographical disparities in cancer related outcomes is required to inform the development of effective interventions to improve the health and welfare of regional Australians.
- Published
- 2017
- Full Text
- View/download PDF
32. The OnTrack Diabetes Web-Based Program for Type 2 Diabetes and Dysphoria Self-Management: A Randomized Controlled Trial Protocol.
- Author
-
Cassimatis M, Kavanagh DJ, Hills AP, Smith AC, Scuffham PA, Gericke C, and Parham S
- Abstract
Background: The prevalence of type 2 diabetes is rising with the majority of patients practicing inadequate disease self-management. Depression, anxiety, and diabetes-specific distress present motivational challenges to adequate self-care. Health systems globally struggle to deliver routine services that are accessible to the entire population, in particular in rural areas. Web-based diabetes self-management interventions can provide frequent, accessible support regardless of time and location, Objective: This paper describes the protocol of an Australian national randomized controlled trial (RCT) of the OnTrack Diabetes program, an automated, interactive, self-guided Web program aimed to improve glycemic control, diabetes self-care, and dysphoria symptoms in type 2 diabetes patients., Methods: A small pilot trial is conducted that primarily tests program functionality, efficacy, and user acceptability and satisfaction. This is followed by the main RCT, which compares 3 treatments: (1) delayed program access: usual diabetes care for 3 months postbaseline followed by access to the full OnTrack Diabetes program; (2) immediate program: full access to the self-guided program from baseline onward; and (3) immediate program plus therapist support via Functional Imagery Training (FIT). Measures are administered at baseline and at 3, 6, and 12 months postbaseline. Primary outcomes are diabetes self-care behaviors (physical activity participation, diet, medication adherence, and blood glucose monitoring), glycated hemoglobin A1c (HbA1c) level, and diabetes-specific distress. Secondary outcomes are depression, anxiety, self-efficacy and adherence, and quality of life. Exposure data in terms of program uptake, use, time on each page, and program completion, as well as implementation feasibility will be conducted., Results: This trial is currently underway with funding support from the Wesley Research Institute in Brisbane, Australia., Conclusions: This is the first known trial of an automated, self-guided, Web-based support program that uses a holistic approach in targeting both type 2 diabetes self-management and dysphoria. Findings will inform the feasibility of implementing such a program on an ongoing basis, including in rural and regional locations., Trial Registration: Australian and New Zealand Clinical Trials Registration number: ACTRN12612000620820; https://anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12612000620820 (Archived by WebCite at http://www.webcitation.org/6a3BeXC5m).
- Published
- 2015
- Full Text
- View/download PDF
33. Development of the OnTrack Diabetes Program.
- Author
-
Cassimatis M, Kavanagh DJ, Hills AP, Smith AC, Scuffham PA, Edge S, Gibson J, and Gericke C
- Abstract
Background: Type 2 diabetes affects an estimated 347 million people worldwide and often leads to serious complications including blindness, kidney disease, and limb amputation. Comorbid dysphoria is common and is an independent risk factor for poor glycaemic control. Professional support for diabetes self-management and dysphoria has limited availability and involves high costs, especially after regular hours, and in rural and remote areas. Web-based cognitive behavior therapy offers highly accessible, acceptable, and cost-effective support for people with diabetes. This paper describes the development of OnTrack Diabetes, a self-guided, Web-based program to promote improved physical and emotional self-management in people with Type 2 diabetes., Objective: The objective of the study is to describe the development of the OnTrack Diabetes program, which is a self-guided, Web-based program aimed to promote euthymia and improved disease self-management in people with Type 2 diabetes., Methods: Semistructured interviews with 12 general practitioners and 13 patients with Type 2 diabetes identified enablers of and barriers to effective diabetes self-management, requirements for additional support, and potential program elements. Existing resources and research data informed the development of content, and consultants from relevant disciplines provided feedback on draft segments and reviewed the program before release. Using a self-guided delivery format contained costs, in addition to adapting program features and modules from an existing OnTrack program., Results: A separate paper describes the protocol for a randomized controlled trial to provide this required evaluation., Conclusions: Development of the OnTrack Diabetes program demonstrates strategies that help ensure that a program is acceptable to users. The next stages involve testing users' experiences and examining the program's effectiveness and cost-effectiveness in randomized controlled trials., Trial Registration: The Australian New Zealand Clinical Trials Registry (ACTRN): 12614001126606; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?ACTRN=12614001126606 (Archived by WebCite at http://www.webcitation.org/6U0Fh3vOj).
- Published
- 2015
- Full Text
- View/download PDF
34. The craving experience questionnaire: a brief, theory-based measure of consummatory desire and craving.
- Author
-
May J, Andrade J, Kavanagh DJ, Feeney GF, Gullo MJ, Statham DJ, Skorka-Brown J, Connolly JM, Cassimatis M, Young RM, and Connor JP
- Subjects
- Adolescent, Adult, Aged, Cacao, Ethanol, Factor Analysis, Statistical, Female, Food, Humans, Male, Middle Aged, Psychological Theory, Surveys and Questionnaires, Tobacco Products, Young Adult, Alcohol Drinking psychology, Behavior, Addictive psychology, Craving, Smoking psychology
- Abstract
Background and Aims: Research into craving is hampered by lack of theoretical specification and a plethora of substance-specific measures. This study aimed to develop a generic measure of craving based on elaborated intrusion (EI) theory. Confirmatory factor analysis (CFA) examined whether a generic measure replicated the three-factor structure of the Alcohol Craving Experience (ACE) scale over different consummatory targets and time-frames., Design: Twelve studies were pooled for CFA. Targets included alcohol, cigarettes, chocolate and food. Focal periods varied from the present moment to the previous week. Separate analyses were conducted for strength and frequency forms., Setting: Nine studies included university students, with single studies drawn from an internet survey, a community sample of smokers and alcohol-dependent out-patients., Participants: A heterogeneous sample of 1230 participants., Measurements: Adaptations of the ACE questionnaire., Findings: Both craving strength [comparative fit indices (CFI = 0.974; root mean square error of approximation (RMSEA) = 0.039, 95% confidence interval (CI) = 0.035-0.044] and frequency (CFI = 0.971, RMSEA = 0.049, 95% CI = 0.044-0.055) gave an acceptable three-factor solution across desired targets that mapped onto the structure of the original ACE (intensity, imagery, intrusiveness), after removing an item, re-allocating another and taking intercorrelated error terms into account. Similar structures were obtained across time-frames and targets. Preliminary validity data on the resulting 10-item Craving Experience Questionnaire (CEQ) for cigarettes and alcohol were strong., Conclusions: The Craving Experience Questionnaire (CEQ) is a brief, conceptually grounded and psychometrically sound measure of desires. It demonstrates a consistent factor structure across a range of consummatory targets in both laboratory and clinical contexts., (© 2014 Society for the Study of Addiction.)
- Published
- 2014
- Full Text
- View/download PDF
35. Effects of type 2 diabetes behavioural telehealth interventions on glycaemic control and adherence: a systematic review.
- Author
-
Cassimatis M and Kavanagh DJ
- Subjects
- Blood Glucose Self-Monitoring psychology, Diabetes Mellitus, Type 2 blood, Health Services Accessibility, Humans, Treatment Outcome, Blood Glucose Self-Monitoring methods, Diabetes Mellitus, Type 2 therapy, Patient Compliance psychology, Telemedicine statistics & numerical data
- Abstract
We reviewed the effect of behavioural telehealth interventions on glycaemic control and diabetes self-management in patients with type 2 diabetes. The databases CINAHL, Medline and psychINFO were searched in August 2012. Journal articles were selected that had been published in English with a randomized controlled trial design using a usual care comparison group, and in which the primary intervention component was delivered by telehealth. Relevant outcome measures were glycaemic control and one or more of the following diabetes self-care areas: diet, physical activity, blood glucose self-monitoring (BGSM) or medication adherence. Interventions were excluded if they were primarily based on telemonitoring. The search retrieved 1027 articles, from which 49 were selected based on their title and abstract. Fourteen articles (reporting 13 studies) met the eligibility criteria for inclusion. Four studies reported significant improvements in glycaemic control. Five of eight studies on dietary adherence reported significant treatment effects, as did five of eight on physical activity, four of nine on blood glucose self-monitoring, and three of eight on medication adherence. Overall, behavioural telehealth interventions show promise in improving the diabetes self-care and glycaemic control of people with type 2 diabetes.
- Published
- 2012
- Full Text
- View/download PDF
36. Randomised controlled trial of an automated, interactive telephone intervention to improve type 2 diabetes self-management (Telephone-Linked Care Diabetes Project): study protocol.
- Author
-
Bird D, Oldenburg B, Cassimatis M, Russell A, Ash S, Courtney MD, Scuffham PA, Stewart I, Wootton R, and Friedman RH
- Subjects
- Adolescent, Adult, Aged, Female, Humans, Male, Middle Aged, Program Evaluation, Quality of Health Care, Queensland, Surveys and Questionnaires, Young Adult, Diabetes Mellitus, Type 2 drug therapy, Self Care, Telemedicine
- Abstract
Background: An estimated 285 million people worldwide have diabetes and its prevalence is predicted to increase to 439 million by 2030. For the year 2010, it is estimated that 3.96 million excess deaths in the age group 20-79 years are attributable to diabetes around the world. Self-management is recognised as an integral part of diabetes care. This paper describes the protocol of a randomised controlled trial of an automated interactive telephone system aiming to improve the uptake and maintenance of essential diabetes self-management behaviours., Methods/design: A total of 340 individuals with type 2 diabetes will be randomised, either to the routine care arm, or to the intervention arm in which participants receive the Telephone-Linked Care (TLC) Diabetes program in addition to their routine care. The intervention requires the participants to telephone the TLC Diabetes phone system weekly for 6 months. They receive the study handbook and a glucose meter linked to a data uploading device. The TLC system consists of a computer with software designed to provide monitoring, tailored feedback and education on key aspects of diabetes self-management, based on answers voiced or entered during the current or previous conversations. Data collection is conducted at baseline (Time 1), 6-month follow-up (Time 2), and 12-month follow-up (Time 3). The primary outcomes are glycaemic control (HbA1c) and quality of life (Short Form-36 Health Survey version 2). Secondary outcomes include anthropometric measures, blood pressure, blood lipid profile, psychosocial measures as well as measures of diet, physical activity, blood glucose monitoring, foot care and medication taking. Information on utilisation of healthcare services including hospital admissions, medication use and costs is collected. An economic evaluation is also planned., Discussion: Outcomes will provide evidence concerning the efficacy of a telephone-linked care intervention for self-management of diabetes. Furthermore, the study will provide insight into the potential for more widespread uptake of automated telehealth interventions, globally., Trial Registration Number: ACTRN12607000594426.
- Published
- 2010
- Full Text
- View/download PDF
37. Metronidazole neurotoxicosis in two cats.
- Author
-
Caylor KB and Cassimatis MK
- Subjects
- Animals, Cats, Central Nervous System Diseases chemically induced, Central Nervous System Diseases diagnosis, Diagnosis, Differential, Giardiasis drug therapy, Giardiasis veterinary, Inflammatory Bowel Diseases drug therapy, Inflammatory Bowel Diseases veterinary, Male, Anti-Infective Agents adverse effects, Cat Diseases diagnosis, Central Nervous System Diseases veterinary, Metronidazole adverse effects
- Abstract
Two cats were presented for neurological dysfunction from suspected metronidazole toxicity. One cat was receiving 111 mg/kg body weight per day of metronidazole for 9 weeks. After 9 weeks, the dose was increased to 222 mg/kg body weight per day, and 2 days later the cat began to experience progressive neurological signs that culminated in generalized seizures. The second cat was receiving metronidazole at a total dose of 58 mg/kg body weight per day for 6 months. This cat experienced acute onset of ataxia and alteration in mentation. Laboratory evaluations in both cases were without significant findings. The neurological signs in both cats resolved within days of initiating supportive therapy and withdrawal of the drug. This report describes the two cases and discusses the etiology of metronidazole neurotoxicosis.
- Published
- 2001
- Full Text
- View/download PDF
Catalog
Discovery Service for Jio Institute Digital Library
For full access to our library's resources, please sign in.