10 results on '"Cassar, Mark P"'
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2. Multiorgan MRI findings after hospitalisation with COVID-19 in the UK (C-MORE): a prospective, multicentre, observational cohort study
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Raman, Betty, McCracken, Celeste, Cassar, Mark P, Moss, Alastair J, Finnigan, Lucy, Samat, Azlan Helmy A, Ogbole, Godwin, Tunnicliffe, Elizabeth M, Alfaro-Almagro, Fidel, Menke, Ricarda, Xie, Cheng, Gleeson, Fergus, Lukaschuk, Elena, Lamlum, Hanan, McGlynn, Kevin, Popescu, Iulia A, Sanders, Zeena-Britt, Saunders, Laura C, Piechnik, Stefan K, Ferreira, Vanessa M, Nikolaidou, Chrysovalantou, Rahman, Najib M, Ho, Ling-Pei, Harris, Victoria C, Shikotra, Aarti, Singapuri, Amisha, Pfeffer, Paul, Manisty, Charlotte, Kon, Onn M, Beggs, Mark, O'Regan, Declan P, Fuld, Jonathan, Weir-McCall, Jonathan R, Parekh, Dhruv, Steeds, Rick, Poinasamy, Krisnah, Cuthbertson, Dan J, Kemp, Graham J, Semple, Malcolm G, Horsley, Alexander, Miller, Christopher A, O'Brien, Caitlin, Shah, Ajay M, Chiribiri, Amedeo, Leavy, Olivia C, Richardson, Matthew, Elneima, Omer, McAuley, Hamish J C, Sereno, Marco, Saunders, Ruth M, Houchen-Wolloff, Linzy, Greening, Neil J, Bolton, Charlotte E, Brown, Jeremy S, Choudhury, Gourab, Diar Bakerly, Nawar, Easom, Nicholas, Echevarria, Carlos, Marks, Michael, Hurst, John R, Jones, Mark G, Wootton, Daniel G, Chalder, Trudie, Davies, Melanie J, De Soyza, Anthony, Geddes, John R, Greenhalf, William, Howard, Luke S, Jacob, Joseph, Man, William D-C, Openshaw, Peter J M, Porter, Joanna C, Rowland, Matthew J, Scott, Janet T, Singh, Sally J, Thomas, David C, Toshner, Mark, Lewis, Keir E, Heaney, Liam G, Harrison, Ewen M, Kerr, Steven, Docherty, Annemarie B, Lone, Nazir I, Quint, Jennifer, Sheikh, Aziz, Zheng, Bang, Jenkins, R Gisli, Cox, Eleanor, Francis, Susan, Halling-Brown, Mark, Chalmers, James D, Greenwood, John P, Plein, Sven, Hughes, Paul J C, Thompson, A A Roger, Rowland-Jones, Sarah L, Wild, James M, Kelly, Matthew, Treibel, Thomas A, Bandula, Steven, Aul, Raminder, Miller, Karla, Jezzard, Peter, Smith, Stephen, Nichols, Thomas E, McCann, Gerry P, Evans, Rachael A, Wain, Louise V, Brightling, Christopher E, Neubauer, Stefan, Baillie, J K, Shaw, Alison, Hairsine, Brigid, Kurasz, Claire, Henson, Helen, Armstrong, Lisa, Shenton, Liz, Dobson, H, Dell, Amanda, Lucey, Alice, Price, Andrea, Storrie, Andrew, Pennington, Chris, Price, Claire, Mallison, Georgia, Willis, Gemma, Nassa, Heeah, Haworth, Jill, Hoare, Michaela, Hawkings, Nancy, Fairbairn, Sara, Young, Susan, Walker, S, Jarrold, I, Sanderson, Amy, David, C, Chong-James, K, Zongo, O, James, W Y, Martineau, A, King, Bernie, Armour, C, McAulay, D, Major, E, McGinness, Jade, McGarvey, L, Magee, N, Stone, Roisin, Drain, S, Craig, T, Bolger, A, Haggar, Ahmed, Lloyd, Arwel, Subbe, Christian, Menzies, Daniel, Southern, David, McIvor, Emma, Roberts, K, Manley, R, Whitehead, Victoria, Saxon, W, Bularga, A, Mills, N L, El-Taweel, Hosni, Dawson, Joy, Robinson, Leanne, Saralaya, Dinesh, Regan, Karen, Storton, Kim, Brear, Lucy, Amoils, S, Bermperi, Areti, Elmer, Anne, Ribeiro, Carla, Cruz, Isabel, Taylor, Jessica, Worsley, J, Dempsey, K, Watson, L, Jose, Sherly, Marciniak, S, Parkes, M, McQueen, 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A, Wight, A, Bailey, L, Ashish, A, Robinson, E, Cooper, J, Broadley, A, Turnbull, A, Brookes, C, Sarginson, C, Ionita, D, Redfearn, H, Elliott, K, Barman, L, Griffiths, L, Guy, Z, Gill, Rhyan, Nathu, Rashmita, Harris, Edward, Moss, P, Finnigan, J, Saunders, Kathryn, Saunders, Peter, Kon, S, Kon, Samantha S, O'Brien, Linda, Shah, K, Shah, P, Richardson, Emma, Brown, V, Brown, M, Brown, Jo, Brown, J, Brown, Ammani, Brown, Angela, Choudhury, N, Jones, S, Jones, H, Jones, L, Jones, I, Jones, G, Jones, Heather, Jones, Don, Davies, Ffyon, Davies, Ellie, Davies, Kim, Davies, Gareth, Davies, Gwyneth A, Howard, K, Porter, Julie, Rowland, J, Rowland, A, Scott, Kathryn, Singh, Suver, Singh, Claire, Thomas, S, Thomas, Caradog, Lewis, Victoria, Lewis, J, Lewis, D, Harrison, P, Francis, C, Francis, R, Hughes, Rachel Ann, Hughes, Joan, Hughes, A D, Thompson, T, Kelly, S, Smith, D, Smith, Nikki, Smith, Andrew, Smith, Jacqui, Smith, Laurie, Smith, Susan, Evans, Teriann, Evans, Ranuromanana I, Evans, D, Evans, R, Evans, H, and Evans, J
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- 2023
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3. Kiosk 2R-FC-01 - Improving Sex-based Differences in ECG Diagnostic Performance for CMR Abnormalities Post Severe COVID-19 Infections
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Samat, Azlan Helmy Abd, Mahmod, Masliza, Lewandowski, Adam, McCracken, Celeste, Cassar, Mark P, Akhtar, Abid M, Ashkir, Zakariye, Moss, Alastair J, Manisty, Charlotte, Treibel, Thomas A, Lukaschuk, Elena, Piechnik, Stefan, Ferreira, Vanessa, Nikolaidou, Chrysovalantou, Miller, Christopher, Chiribiri, Amedeo, O'Regan, Declan, Steeds, Richard P, Weir-McCall, Jonathan R, Plein, Sven, McCann, Gerry, Evans, Rachael A, Brightling, Christopher E., Neubauer, Stefan, and Raman, Betty
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- 2024
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4. Altered lung physiology in two cohorts after COVID-19 infection as assessed by computed cardiopulmonography
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Magor-Elliott, Snapper R. M., primary, Alamoudi, Asma, additional, Chamley, Rebecca R., additional, Xu, Haopeng, additional, Wellalagodage, Tishan, additional, McDonald, Rory P., additional, O’Brien, David, additional, Collins, Jonathan, additional, Coombs, Ben, additional, Winchester, James, additional, Sellon, Ed, additional, Xie, Cheng, additional, Sandhu, Dominic, additional, Fullerton, Christopher J., additional, Couper, John H., additional, Smith, Nicholas M. J., additional, Richmond, Graham, additional, Cassar, Mark P., additional, Raman, Betty, additional, Talbot, Nick P., additional, Bennett, Alexander N., additional, Nicol, Edward D., additional, Ritchie, Grant A. D., additional, Petousi, Nayia, additional, Holdsworth, David A., additional, and Robbins, Peter A., additional
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- 2022
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5. Improving Sex-based Differences in ECG Diagnostic Performance for CMR Abnormalities Post Severe COVID-19 Infections
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Samat, Azlan Helmy Abd, Mahmod, Masliza, Lewandowski, Adam, McCracken, Celeste, Cassar, Mark P, Akhtar, Abid M, Ashkir, Zakariye, Moss, Alastair J, Manisty, Charlotte, Treibel, Thomas A, Lukaschuk, Elena, Piechnik, Stefan, Ferreira, Vanessa, Nikolaidou, Chrysovalantou, Miller, Christopher, Chiribiri, Amedeo, O'Regan, Declan, Steeds, Richard P, Weir-McCall, Jonathan R, Plein, Sven, McCann, Gerry, Evans, Rachael A, Brightling, Christopher E., Neubauer, Stefan, and Raman, Betty
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- 2024
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6. Quantification of Ischemia As a Prognostic Mandate for Coronary Revascularization in Asymptomatic Patients: How Much Is Enough?
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Shabbir, Asad, Fan, Lampson, Fraser, Gregory, Cassar, Mark Philip, and Swinburn, Jon
- Abstract
The aim of this study was to investigate whether asymptomatic patients with known coronary artery disease and demonstrable myocardial ischemia warrant revascularization on prognostic grounds. A Medline and PubMed search was performed, including 7 trials with data discussed and concise reviews of prominent articles in the field. The magnitude of inducible ischemia in those with known coronary disease correlates closely with poor cardiovascular outcomes in terms of death, myocardial infarction, hospitalization, and revascularization. Patients with ≥10% inducible ischemia experience a survival advantage when revascularized with a reduction in mortality of greater than 50% regardless of symptoms (P< 0.00001). Evidence also suggests that left ventricular function remains preserved in those who are revascularized when compared with medical therapy alone; left ventricular ejection fraction 53.9% versus 48.8% (P< 0.001). Silent ischemia is a useful prognostic marker in those with known coronary disease. It is recommended that asymptomatic patients with known coronary disease be revascularized on prognostic grounds if ≥10% ischemia can be demonstrated on nuclear or myocardial perfusion scan, ≥3 segments of regional wall motion abnormality on stress echocardiography/cardiac magnetic resonance imaging, or ≥2 segments with perfusion deficits on stress perfusion cardiac magnetic resonance imaging.
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- 2019
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7. One-Hour High Sensitivity Troponin Testing: A Safe and Effective Triage Tool for the Emergency Department
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Shabbir, Asad, Fan, Lampson, Fraser, Gregory, Cassar, Mark Philip, and Swinburn, Jon
- Abstract
The latest European Society of Cardiology guideline on the management of acute coronary syndromes without persistent ST-elevation stipulates several acceptable pathways through which patients presenting with chest pain can be assessed for unstable coronary disease. This article reviews the data behind the “rule-in and rule-out algorithm,” which can exclude acute myocardial infarction within 1 hour of presentation through the use of fifth generation high-sensitivity troponin assays.
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- 2019
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8. Evaluating possible prehistoric cave art in the central Mediterranean: Analyses of pigment traces and identification of taphonomic processes at Għar Ħasan, Malta
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Guagnin, Maria, Haburaj, Vincent, Groucutt, Huw S., Hoelzmann, Philipp, Gauci, Ritienne, Vella, Nicholas C., Parisi, Cetty, Cassar, Mark, Cassar, Yasmin, Asciak, Gillian, and Scerri, Eleanor
- Abstract
•Most of the analysed pigment traces were applied within the last century.•One key panel is likely older and may have been painted in antiquity.•Pigment in a poor state of preservation introduces many variables of contamination.•Low-tech methodologies (microscopy and image enhancement) were extremely successful.
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- 2023
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9. Abstract 10985: Cardiopulmonary Assessment of COVID-19 Survivors Stratified by Acute Disease Severity and Post-Acute Symptoms
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Szekely, Yishay, Ghantous, Ehab, SAdon, Sapir, De Marzo, Vincenzo, Clavario, Piero, Porto, Italo, Crisafulli, Ernesto, Vannini, Luca, Quijada-Fumero, Alejandro, Laynez-Carnicero, Ana, Cassar, Mark Philip, Neubauer, Stefan, Raman, Betty, Banai, Shmuel, and Topilsky, Yan
- Abstract
Introduction:Studies have demonstrated a reduction in peak oxygen consumption (VO2) post-acute COVID-19. We sought to determine the association between acute COVID-19 severity, post-acute symptoms and peak VO2after recovery.Methods:This study analyzed data from patients who recovered from COVID-19 and underwent cardiopulmonary exercise testing (CPET) as part of prospective studies in 5 centers across UK and Europe. Patients were asked to report current symptoms. Peak VO2, lung volumes, gas exchange, ventilatory efficiency, heart rate and O2pulse were measured in a standard symptom-limited incremental cycle ergometer CPET.Results:Among 417 patients examined 136±63 days after recovery from COVID-19, 164 (39%) were female. Mean age was 56.9±13.3 years. The spectrum of acute COVID-19 severity included critical (N=47; 11.3%), severe (180; 43.2%), moderate (75; 18.0%) and mild (115; 27.5%) illness. The most common post-acute symptom was dyspnea (200; 48%), followed by muscle pain (173; 41%). Mean peak respiratory exchange ratio was 1.13±0.1, and did not vary across acute disease severity or post-acute symptom status. There was no significant difference in peak VO2as % from predicted in mild to critical acute disease: 84.0±2.1%, 91.4±2.6%, 82.9±1.7% and 83.7±3.2%, respectively (p=0.06). Patients with dyspnea or muscle pain had each lower peak VO2as % from predicted, compared to patients free of the specific symptom (81.3±21.2% vs. 88.1±22.9%, p=0.002 and 78.6±19.1% vs. 88.2±22.0%, p<0.0001, respectively). Both dyspnea and muscle pain were each associated with significantly lower peak heart rate and peak O2pulse, as well as lower lung volumes and gas exchange capacity, compared to patients free of the specific symptom.Conclusions:Common post-acute COVID-19 symptoms, and not acute disease severity, are associated with lower peak VO2 in CPET. Parameters related to both cardiac and pulmonary function seem to play a role in this reduced physical performance.
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- 2022
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10. Left atrial tumor thrombus in metastatic thyroid cancer.
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Cassar, Mark Philip and Stirrup, James
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- 2020
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