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32 results on '"Casella, Samuel J."'

1. Safety and Efficacy of Lonapegsomatropin in Children With Growth Hormone Deficiency: enliGHten Trial 2-Year Results

Author

Maniatis, Aristides K, primary, Casella, Samuel J, additional, Nadgir, Ulhas M, additional, Hofman, Paul L, additional, Saenger, Paul, additional, Chertock, Elena D, additional, Aghajanova, Elena M, additional, Korpal-Szczyrska, Maria, additional, Vlachopapadopoulou, Elpis, additional, Malievskiy, Oleg, additional, Chaychenko, Tetyana, additional, Cappa, Marco, additional, Song, Wenjie, additional, Mao, Meng, additional, Mygind, Per Holse, additional, Smith, Alden R, additional, Chessler, Steven D, additional, Komirenko, Allison S, additional, Beckert, Michael, additional, Shu, Aimee D, additional, and Thornton, Paul S, additional

Published
2022
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2. Switching to Weekly Lonapegsomatropin from Daily Somatropin in Children with Growth Hormone Deficiency: The fliGHt Trial

Author

Maniatis, Aristides K., primary, Nadgir, Ulhas, additional, Saenger, Paul, additional, Reifschneider, Kent L., additional, Abuzzahab, Jennifer, additional, Deeb, Larry, additional, Fox, Larry A., additional, Woods, Katie A., additional, Song, Wenjie, additional, Mao, Meng, additional, Chessler, Steven D., additional, Komirenko, Allison S., additional, Shu, Aimee D., additional, Casella, Samuel J., additional, and Thornton, Paul S., additional

Published
2022
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4. Efficacy and Safety of up to 2 Years of Treatment With TransCon hGH (Lonapegsomatropin) in Treatment-Naïve and Treatment-Experienced Children With Growth Hormone Deficiency

Author

Maniatis, Aristides K, primary, Casella, Samuel J, additional, Nadgir, Ulhas M, additional, Hofman, Paul, additional, Saenger, Paul, additional, Chertok, Elena, additional, Aghajanova, Elena M, additional, Song, Wenjie, additional, Mao, Meng, additional, Chessler, Steven D, additional, Komirenko, Allison, additional, Beckert, Michael, additional, Shu, Aimee D, additional, and Thornton, Paul S, additional

Published
2021
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5. SAT-LB16 Maintenance of Favorable Treatment Effect of Once-Weekly TransCon hGH for Children With Growth Hormone Deficiency: Interim Analysis From the Enlighten Long-Term Extension Trial

Author

Maniatis, Aristides K, primary, Casella, Samuel J, primary, Nadgir, Ulhas M, primary, Mick, Gail J, primary, Hofman, Paul, primary, Saenger, Paul, primary, Chertok, Elena D, primary, Warshauer, Jeremy, primary, Song, Wenjie, primary, Peng, Jessica M, primary, Komirenko, Allison S, primary, Shu, Aimee D, primary, Beckert, Michael, primary, Aghajanova, Elena M, primary, and Thornton, Paul S, primary

Published
2020
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6. OR10-05 Phase 3 FliGHt Trial: Experience of Switching from Daily Growth Hormone Therapy to Once-Weekly TransCon HGH in Children with Growth Hormone Deficiency

Author

Maniatis, Aristides K, primary, Nadgir, Ulhas, primary, Saenger, Paul, primary, Mick, Gail, primary, Reifschneider, Kent L, primary, Abuzzahab, Mary Jennifer, primary, Deeb, Larry, primary, Fox, Larry A, primary, Woods, Katie A, primary, Peng, Jessica M, primary, Karpf, David B, primary, Shu, Aimee D, primary, Song, Wenjie, primary, Casella, Samuel J, primary, and Thornton, Paul S, primary

Published
2020
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18. Ambiguous genitalia with perineoscrotal hypospadias in 46,XY individuals: long-term medical, surgical, and psychosexual outcome

Author

Migeon, Claude J., Wisniewski, Amy B., Gearhart, John P., Meyer-Bahlburg, Heino F.L., Rock, John A., Brown, Terry R., Casella, Samuel J., Maret, Alexander, Ngai, Ka Ming, Money, John, and Berkovitz, Gary D.

Subjects
Sex differentiation disorders -- Psychological aspects, Hypospadias -- Psychological aspects
Abstract

Objectives. To identify and study adults (21 years or older) who have a 46,XY karyotype and presented as infants or children with genital ambiguity, including a small phallus and perineoscrotal hypospadias, reared male or female. Methods. Participants were classified according to the cause underlying their intersex condition based on review of medical and surgical records. Long-term medical and surgical outcome was assessed with a written questionnaire and physical examination. Long-term psychosexual development was assessed with a written questionnaire and semistructured interview. Results. Thirty-nine (72%) of 54 eligible patients participated. The cause underlying genital ambiguity of participants included partial androgen insensitivity syndrome (n = 14; 5 men and 9 women), partial gonadal dysgenesis (n = 11; 7 men and 4 women), and other intersex conditions. Men had significantly more genital surgeries (mean: 5.8) than women (mean: 2.1), and physician-rated cosmetic appearance of the genitalia was significantly worse for men than for women. The majority of participants were satisfied with their body image, and men and women did not differ on this measure. Most men (90%) and women (83%) had sexual experience with a partner. Men and women did not differ in their satisfaction with their sexual function. The majority of participants were exclusively heterosexual, and men considered themselves to be masculine and women considered themselves to be feminine. Finally, 23% of participants (5 men and 4 women) were dissatisfied with their sex of rearing determined by their parents and physicians. Conclusions. Either male or female sex of rearing can lead to successful long-term outcome for the majority of cases of severe genital ambiguity in 46,XY individuals. We discuss factors that should be considered by parents and physicians when deciding on a sex of rearing for such infants. Pediatrics 2002;110(3). URL: http://www. pediatrics.org/cgi/content/full/110/3/e31; intersex, sex assignment, gender, androgen insensitivity, gonadal dysgenesis, psychosexual, genital reconstruction, hormone replacement.

Published
2002

31. Asthma and diabetes in adolescents. Preface.

Author

Wood RA and Casella SJ

Subjects
Adolescent, Chronic Disease, Diabetes Mellitus, Type 1 classification, Diabetes Mellitus, Type 2 classification, Humans, Patient Education as Topic, Asthma epidemiology, Diabetes Mellitus, Type 1 epidemiology, Diabetes Mellitus, Type 2 epidemiology
Published
2010

32. Gizmos and gadgets in diabetes care: new tools for sweet kids.

Author

Christiano AS and Casella SJ

Subjects
Child, Equipment Design, Extracellular Fluid chemistry, Glucose analysis, Humans, Insulin Infusion Systems, Blood Glucose Self-Monitoring instrumentation, Blood Glucose Self-Monitoring methods, Hypoglycemic Agents administration & dosage, Insulin administration & dosage
Abstract

Diabetes care has become more complex as we strive to help children with diabetes achieve and maintain tight glycemic control. The technologic advances described herein have provided the means for safer, more convenient, and more effective diabetes care.

Published
2006
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