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209 results on '"Casella, Carmela"'

2. Prevalence of Fabry disease and GLA variants in young patients with acute stroke: The challenge to widen the screening. The Fabry-Stroke Italian Registry

Author

Romani, Ilaria, Sarti, Cristina, Nencini, Patrizia, Pracucci, Giovanni, Zedde, Marialuisa, Cianci, Vittoria, Nucera, Antonia, Moller, Jessica, Orsucci, Daniele, Toni, Danilo, Palumbo, Pasquale, Casella, Carmela, Pinto, Vincenza, Barbarini, Leonardo, Bella, Rita, Scoditti, Umberto, Ragno, Michele, Mezzapesa, Domenico Maria, Tassi, Rossana, Volpi, Gino, Diomedi, Marina, Bigliardi, Guido, Cavallini, Anna Maria, Chiti, Alberto, Ricci, Stefano, Cecconi, Emanuela, Linoli, Giovanni, Sacco, Simona, Rasura, Maurizia, Giordano, Antonello, Bonetti, Bruno, Melis, Marta, Cariddi, Lucia Princiotta, Dossi, Roberto Currò, Grisendi, Ilaria, Aguglia, Umberto, Di Ruzza, Maria Rita, Melis, Maurizio, Sbardella, Emilia, Vista, Marco, Valenti, Raffaella, Musolino, Rosa Fortunata, Passarella, Bruno, Direnzo, Vita, Pennisi, Giovanni, Genovese, Antonio, Di Marzio, Fabio, Sgobio, Rossana, Acampa, Maurizio, Nannucci, Serena, Dagostino, Federica, Dell'Acqua, Maria Luisa, Cuzzoni, Maria Giovanna, Picchioni, Antonella, Calchetti, Benedetta, Notturno, Francesca, Di Lisi, Filomena, Forlivesi, Stefano, Delodovici, Maria Luisa, Buechner, Susanne Christiane, Biagini, Silvia, Accavone, Donatella, Manna, Raffaele, Morrone, Amelia, and Inzitari, Domenico

Published
2024
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3. Ischemic stroke and reperfusion therapies in diabetic patients

Author

Currò, Carmelo Tiberio, Fiume, Giulia, Cotroneo, Masina, Russo, Giuseppina, Casella, Carmela, Dell’Aera, Cristina, Fazio, Maria Carolina, Grillo, Francesco, Laganà, Angelina, Trimarchi, Giuseppe, Toscano, Antonio, Vinci, Sergio Lucio, Musolino, Rosa Fortunata, and La Spina, Paolino

Published
2022
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4. Fabry-Stroke Italian Registry (FSIR): a nationwide, prospective, observational study about incidence and characteristics of Fabry-related stroke in young-adults. Presentation of the study protocol

Author

Romani, Ilaria, Nencini, Patrizia, Sarti, Cristina, Pracucci, Giovanni, Zedde, Marialuisa, Nucera, Antonia, Cianci, Vittoria, Moller, Jessica, Toni, Danilo, Orsucci, Daniele, Casella, Carmela, Pinto, Vincenza, Palumbo, Pasquale, Barbarini, Leonardo, Bella, Rita, Ragno, Michele, Scoditti, Umberto, Mezzapesa, Domenico Maria, Tassi, Rossana, Diomedi, Marina, Cavallini, Anna, Volpi, Gino, Chiti, Alberto, Bigliardi, Guido, Sacco, Simona, Linoli, Giovanni, Ricci, Stefano, Giordano, Antonello, Bonetti, Bruno, Rasura, Maurizia, Cecconi, Emanuela, Princiotta Cariddi, Lucia, Currò Dossi, Roberto, Melis, Marta, Consoli, Domenico, Guidetti, Donata, Biagini, Silvia, Accavone, Donatella, and Inzitari, Domenico

Published
2022
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6. Ischemic Stroke and Asymptomatic Pulmonary Opacities

Author

Currò, Carmelo Tiberio, Cotroneo, Masina, Ciacciarelli, Antonio, Dell'Aera, Cristina, Grillo, Francesco, La Spina, Paolino, Fazio, Maria Carolina, Laganà, Angelina, De Caro, Jolanda, Trimarchi, Giuseppe, Toscano, Antonio, Musolino, Rosa Fortunata, and Casella, Carmela

Published
2022
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10. Foam Cells Analysis from Retrieved Stroke Clot for the Identification of Atherothrombotic Etiology.

Author

Giammello, Fabrizio, Ciacciarelli, Antonio, Cosenza, Domenico, Galletta, Santi, Barresi, Valeria, La Spina, Paolino, Fazio, Maria Carolina, De Caro, Jolanda, Cotroneo, Masina, Dell'Aera, Cristina, Grillo, Francesco, Ammendola, Serena, Tessitore, Agostino, Vinci, Sergio Lucio, Musolino, Rosa Fortunata, Casella, Carmela, and Toscano, Antonio

Subjects
FOAM cells, STROKE, ATHEROSCLEROTIC plaque, ETIOLOGY of diseases, HISTOPATHOLOGY
Abstract

Background: In atherothrombotic acute ischemic stroke (AIS), when the atheroma breaks down, the clot can incorporate foam cells (FCs). The identification of the correct etiology is paramount for secondary stroke prevention. This study aims to evaluate the presence of the FC in the arterial clot, and to determine whether patients with FCs and patients without FCs (NFCs) had different cerebrovascular risk factors, haemato-chemical parameters, and atherosclerotic disease incidence, in order to predict the etiological diagnosis. Methods: We collected 100 clots retrieved by mechanical thrombectomy from 495 consecutive AIS patients with large vessel occlusion. An expert pathologist evaluated the FC presence by histological examination stained with hematoxylin and eosin. Results: We observed FCs in 29/100 (29%) of retrieved clots and divided the patients into two groups, with/without FCs. The two groups had similar clinical and laboratory features, with a discrepancy between the FC presence in the clot and the clinical etiological diagnosis, even if not statistically significant. Conclusions: Our study showed the presence of FCs in approximately one-third of the retrieved clots, but the identification of the clot that presumably comes from the atheromatous plaque rupture tended to disagree with the clinical diagnosis. Future studies may reveal their potential to disclose clot origin or specific patient characteristics, guiding treatment options. [ABSTRACT FROM AUTHOR]

Published
2024
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11. Migraine improvement after spontaneous cervical artery dissection the Italian Project on Stroke in Young Adults (IPSYS)

Author

De Giuli, Valeria, Graziano, Francesca, Zini, Andrea, Zedde, Marialuisa, Patella, Rosalba, Lodigiani, Corrado, Marcheselli, Simona, DeLodovici, Maria Luisa, Paciaroni, Maurizio, Casetta, Ilaria, Giorli, Elisa, Adami, Alessandro, Braga, Massimiliano, Casella, Carmela, Giossi, Alessia, Silvestrelli, Giorgio, Tancredi, Lucia, Lotti, Enrico Maria, Poli, Loris, Caria, Filomena, Piras, Valeria, Cucurachi, Laura, Gamba, Massimo, Grassi, Mario, Padovani, Alessandro, Pezzini, Alessandro, and on behalf of the Italian Project on Stroke in Young Adults (IPSYS) Investigators

Published
2019
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18. Beyond motor recovery after stroke: The role of hand robotic rehabilitation plus virtual reality in improving cognitive function

Author

Rocco Salvatore Calabrò, Rosaria De Luca, Antonino Naro, Gianluca La Rosa, Maria Grazia Maggio, Bruno Porcari, Casella Carmela, Michele Torrisi, Caterina Zichittella, and Maria Cristina De Cola

Subjects
Male, Occupational therapy, medicine.medical_specialty, medicine.medical_treatment, Upper-limb rehabilitation Cognitive functions End-effector robotic devices Stroke, Upper Extremity, Cognition, Physical medicine and rehabilitation, Robotic Surgical Procedures, Physiology (medical), medicine, Humans, Stroke, Motor skill, Rehabilitation, business.industry, Stroke Rehabilitation, Virtual Reality, Recovery of Function, Robotics, General Medicine, Executive functions, medicine.disease, Neurology, Female, Surgery, Neurology (clinical), Motor Deficit, Stroke recovery, business
Abstract

Robot-assisted hand training adopting end-effector devices results in an additional reduction of motor impairment in comparison to usual care alone in different stages of stroke recovery. These devices often allow the patient to perform practical, attentive, and visual-spatial tasks in a semi-virtual reality (VR) setting. We aimed to investigate whether the hand end-effector robotic device AmadeoTM could improve cognitive performance, beyond the motor deficit, as compared to the same amount of occupational treatment focused on the hand. Forty-eight patients (aged 54.3 ± 10.5 years, 62.5% female) affected by either ischemic or hemorrhagic stroke in the chronic phase were enrolled in the study. The experimental group (EG) underwent AmadeoTM robotic training, while the control group (CG) performed occupational therapy involving the upper limb. Patients were assessed at the beginning and at the end of the rehabilitation protocol using a specific neuropsychological battery, as well as motor function tests. The EG showed greater improvements in different cognitive domains, including attentive abilities and executive functions, as well as in hand motor function, as compared to CG. Our study showed that task-oriented VR-based robotic rehabilitation enhanced not only motor function in the paretic arm but also global and specific cognitive abilities in post-stroke patients. We may argue that the hand robotic plus VR-based training may provide patients with an integration of cognitive and motor skill rehabilitation, thus amplifying the functional outcome achievement.

Published
2021
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26. Spinal cord ischemia: A rare manifestation of a floating thrombus

Author

Gardin, Anna, Tiberio Currò, Carmelo, La Spina, Paolo, Brizzi, Teresa, Casella, Carmela, Cotroneo, Masina, Dell'Aera, Cristina, Carolina Fazio, Maria, Grillo, Francesco, Naro, Antonino, Cavallaro, Marco, Galletta, Karol, Granata, Francesca, Toscano, Antonio, and Fortunata Musolino, Rosa

Published
2021
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28. Fabry-Stroke Italian Registry (FSIR): a nationwide, prospective, observational study about incidence and characteristics of Fabry-related stroke in young-adults. Presentation of the study protocol

Author

Romani, Ilaria, primary, Nencini, Patrizia, additional, Sarti, Cristina, additional, Pracucci, Giovanni, additional, Zedde, Marialuisa, additional, Nucera, Antonia, additional, Cianci, Vittoria, additional, Moller, Jessica, additional, Toni, Danilo, additional, Orsucci, Daniele, additional, Casella, Carmela, additional, Pinto, Vincenza, additional, Palumbo, Pasquale, additional, Barbarini, Leonardo, additional, Bella, Rita, additional, Ragno, Michele, additional, Scoditti, Umberto, additional, Mezzapesa, Domenico Maria, additional, Tassi, Rossana, additional, Diomedi, Marina, additional, Cavallini, Anna, additional, Volpi, Gino, additional, Chiti, Alberto, additional, Bigliardi, Guido, additional, Sacco, Simona, additional, Linoli, Giovanni, additional, Ricci, Stefano, additional, Giordano, Antonello, additional, Bonetti, Bruno, additional, Rasura, Maurizia, additional, Cecconi, Emanuela, additional, Princiotta Cariddi, Lucia, additional, Currò Dossi, Roberto, additional, Melis, Marta, additional, Consoli, Domenico, additional, Guidetti, Donata, additional, Biagini, Silvia, additional, Accavone, Donatella, additional, and Inzitari, Domenico, additional

Published
2021
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30. Social cognition in patients with acquired brain lesions: An overview on an under-reported problem.

Author

Maggio, Maria Grazia, Maresca, Giuseppa, Stagnitti, Maria Chiara, Anchesi, Smeralda, Casella, Carmela, Pajno, Valentina, De Luca, Rosaria, Manuli, Alfredo, and Calabrò, Rocco Salvatore

Abstract

Social cognition (SC) consists of mental representations of interpersonal relationships, which are used flexibly by the individual to promote functional social behaviors and achieve the goals. SC is a multidimensional construct and is supported by the activity of distributed neural networks in which different cortical and subcortical regions of the brain are involved. The review aims to evaluate the current literature on SC taking into account how it is compromised in acquired brain injury. Studies performed between 2010 and 2019 and fulfilling the selected criteria were searched on PubMed, Scopus, Cochrane and Web of Sciences databases. Impairment of SC is a neglected but common consequence of ABI, often leading to disordered interpersonal functioning and poor regulation of personal behavior with impaired social adaptation and quality of life of both the patient and his/her family. This review supports the idea that SC could have an important role in the management of neurological patients by both clinicians and caregivers. [ABSTRACT FROM AUTHOR]

Published
2022
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32. Minor stroke with bilateral acute infarctions and combined vascular anomalies: A complex case report

Author

Giammello, Fabrizio, primary, Dell’Aera, Cristina, additional, Grillo, Francesco, additional, Cotroneo, Masina, additional, Casella, Carmela, additional, La Spina, Paolino, additional, Currò, Carmelo T., additional, Velo, Mariano, additional, Granata, Francesca, additional, Toscano, Antonio, additional, Musolino, Rosa F., additional, and Fazio, Maria C., additional

Published
2020
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34. Recurrent intracranial hemorrhage and cerebral venous sinus thrombosis: an atypical case of Neuro-Behçet’s Syndrome

Author

Giammello, Fabrizio, primary, Dell’Aera, Cristina, additional, Grillo, Francesco, additional, Cotroneo, Masina, additional, Casella, Carmela, additional, Fazio, Maria Carolina, additional, La Spina, Paolino, additional, Francalanza, Isabella, additional, Fiorenza, Alessia, additional, Toscano, Antonio, additional, Atzeni, Fabiola, additional, and Musolino, Rosa Fortunata, additional

Published
2020
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35. Isolated Insular Stroke: Clinical Presentation

Author

Giammello, Fabrizio, primary, Cosenza, Domenico, additional, Casella, Carmela, additional, Granata, Francesca, additional, Dell’Aera, Cristina, additional, Fazio, Maria Carolina, additional, La Spina, Paolino, additional, Grillo, Francesco, additional, Cotroneo, Masina, additional, Toscano, Antonio, additional, and Musolino, Rosa Fortunata, additional

Published
2020
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36. Effects of domotics on cognitive, social and personal functioning in patients with chronic stroke: A pilot study

Author

Maggio, Maria Grazia, primary, Maresca, Giuseppa, additional, Russo, Margherita, additional, Stagnitti, Maria Chiara, additional, Anchesi, Smeralda, additional, Casella, Carmela, additional, Zichitella, Caterina, additional, Manuli, Alfredo, additional, De Cola, Maria Cristina, additional, De Luca, Rosaria, additional, and Calabrò, Rocco Salvatore, additional

Published
2020
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38. Is psychosocial rehabilitation useful in older people living in nursing homes? A pilot study on long‐term cognitive and behavioural outcomes.

Author

De Luca, Rosaria, Maggio, Maria Grazia, Leonardi, Simona, Marra, Angela, Casella, Carmela, and Calabrò, Rocco Salvatore

Subjects
PILOT projects, STATISTICS, AFFECT (Psychology), SOCIAL support, COGNITION, CASE-control method, GERIATRIC Depression Scale, REHABILITATION of people with mental illness, QUALITY of life, DATA analysis, SOCIAL skills education, COGNITIVE therapy
Abstract

Background: Age‐related changes in cognitive and behavioural functions, although common, may vary considerably across individuals and cognitive domains. There is limited evidence focusing on the benefits of training based on cognitive/social learning principles in the elderly. The aim of this study is to investigate the effects of Assertive Social Skill Training (ASST) in improving cognitive and mood outcomes in a sample of older patients living in a Sicilian nursing home. Methods: Forty‐seven older subjects were enrolled in this case–control study. Each participant was evaluated by a neuropsychologist, through the administration of a short psychometric battery using the Mini‐Mental State Examination (MMSE), Frontal Assessment Battery (FAB), and Geriatric Depression Scale (GDS), at three time points: before (T0), immediately following (T1), and 6 months after the end of the training (T2). Both groups received cognitive behavioural therapy and psychological support, but the experimental group received the ASST protocol (60 sessions, five times a week, for 12 weeks, each session lasting about 60 min), whilst the control group participated in group meetings with recreational activities. Results: Post‐hoc analysis showed that only patients receiving ASST presented a statistically significant improvement in global cognitive functions (MMSE: P < 0.001), frontal abilities (FAB: P < 0.001), and mood (GDS: P < 0.001); these positive outcomes were maintained at T2. Conclusions: Promising treatments, like the ASST, aimed at potentiating cognitive, behavioural, and social skills, are needed to improve older people's quality of life, especially when they live in nursing homes. [ABSTRACT FROM AUTHOR]

Published
2022
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39. IER-SICH Nomogram to Predict Symptomatic Intracerebral Hemorrhage After Thrombectomy for Stroke

Author

Cappellari, Manuel, Mangiafico, Salvatore, Saia, Valentina, Pracucci, Giovanni, Nappini, Sergio, Nencini, Patrizia, Konda, Daniel, Sallustio, Fabrizio, Vallone, Stefano, Zini, Andrea, Bracco, Sandra, Tassi, Rossana, Bergui, Mauro, Cerrato, Paolo, Pitrone, Antonio, Grillo, Francesco, Saletti, Andrea, De Vito, Alessandro, Gasparotti, Roberto, Magoni, Mauro, Puglielli, Edoardo, Casalena, Alfonsina, Causin, Francesco, Baracchini, Claudio, Castellan, Lucio, Malfatto, Laura, Menozzi, Roberto, Scoditti, Umberto, Comelli, Chiara, Duc, Enrica, Comai, Alessio, Franchini, Enrica, Cosottini, Mirco, Mancuso, Michelangelo, Peschillo, Simone, De Michele, Manuela, Giorgianni, Andrea, Delodovici, Maria Luisa, Lafe, Elvis, Denaro, Maria Federica, Burdi, Nicola, Internò, Saverio, Cavasin, Nicola, Critelli, Adriana, Chiumarulo, Luigi, Petruzzellis, Marco, Doddi, Marco, Carolei, Antonio, Auteri, William, Petrone, Alfredo, Padolecchia, Riccardo, Tassinari, Tiziana, Pavia, Marco, Invernizzi, Paolo, Turcato, Gianni, Forlivesi, Stefano, Ciceri, Elisa Francesca Maria, Bonetti, Bruno, Inzitari, Domenico, Toni, Danilo, Limbucci, Nicola, Consoli, Arturo, Renieri, Leonardo, Fainardi, Enrico, Gandini, Roberto, Pampana, Enrico, Diomedi, Marina, Koch, Giacomo, Verganti, Luca, Sacchetti, Federico, Zelent, Gabriele, Bigliardi, Guido, Picchetto, Livio, Vandelli, Laura, Romano, Daniele Giuseppe, Cioni, Samuele, Gennari, Paola, Cerase, Alfonso, Martini, Giuseppe, Stura, Guido, Daniele, Dino, Naldi, Andrea, Papa, Rosario, Vinci, Sergio Lucio, Bernava, Gianmarco, Velo, Mariano, Caragliano, Antonio, Tessitore, Agostino, Buonomo, Orazio, Musolino, Rossella, La Spina, Paolino, Casella, Carmela, Carolina Fazio, Maria, Cotroneo, Masina, Onofrio, Marcello, Azzini, Cristiano, Casetta, Ilaria, Mardighian, Dikran, Frigerio, Michele, Costa, Angelo, Di Egidio, Vincenzo, Lattanzi, Ruggero, Assetta, Maurizio, Cester, Giacomo, Mavilio, Nicola, Serrati, Carlo, Piazza, Paolo, Epifani, Enrico, Andreone, Andrea, Castellini, Paola, Latte, Lilia, Grisendi, Ilaria, Vaudano, Giacomo, Comelli, Simone, Cavallo, Roberto, Chianale, Gigliola, Simonetti, Luigi, Taglialatela, Francesco, Isceri, Salvatore, Procaccianti, Gaetano, Zaniboni, Anna, Borghi, Annamaria, Bonatti, Giampietro, Ferro, Federica, Bonatti, Matteo, Dall’Ora, Elisa, Currò Dossi, Roberto, Turri, Emanuela, Turri, Mara, Puglioli, Michele, Lazzarotti, Guido, Lauretti, DARIO LUCA, Giannini, Nicola, Maccarone, Miriam, Orlandi, Giovanni, Chiti, Alberto, Guidetti, Giulio, Biraschi, Francesco, Falcou, Anne, Anzini, Alexia, Mancini, Alessandra, Fausti, Silvia, Di Mascio, Maria Teresa, Durastanti, Laura, Sbardella, Emilia, Mellina, Vittorio, Baruzzi, Fabio, Pellegrino, Carlo, Terrana, Alberto, Carimati, Federico, Ruggiero, Maria, Sanna, Antioco, Passarin, Maria Grazia, Colosimo, Cesare, Pedicelli, Alessandro, D’Argento, Francesco, Alexandre, Andrea, Frisullo, Giovanni, Zappoli, Federico, Martignoni, Alessandra, Cavallini, Anna, Persico, Alessandra, Valvassori, Luca, Piano, Mariangela, Agostoni, Elio, Motto, Cristina, Gatti, Antonella, Longoni, Marco, Guccione, Angelo, Tortorella, Rachele, Zampieri, Piergiuseppe, Zimatore, Domenico Sergio, Grazioli, Andrea, Ricciardi, Giuseppe Kenneth, Augelli, Raffaele, Bovi, Paolo, Tomelleri, Giampaolo, Micheletti, Nicola, Semeraro, Vittorio, Lucarelli, Nicola, Ganimede, Maria, Tinelli, Angelica, Pia Prontera, Maria, Pesare, Angela, Cagliari, Enrico, Quatrale, Rocco, Federico, Francesco, Passalacqua, Giovanni, Filauri, Pietro, Orlandi, Berardino, De Santis, Federica, Gabriele, Amleto, Tiseo, Cindy, Armentano, Antonio, Di Benedetto, Olindo, Silvagni, Umberto, Perrotta, Paolo, Crispino, Emanuela, Stancati, Furio, Rizzuto, Stefano, Pugliese, Pierfrancesco, Pisani, Ermanno, Siniscalchi, Antonio, Gaudiano, Carmen, Pirritano, Domenico, Del Giudice, Francesco, Calia, Stefano, Ganci, Giuseppe, Sugo, Annalisa, Scomazzoni, Francesco, Simionato, Franco, Roveri, Luisa, De Nicola, Maurizio, Giannoni, Mirko, Bruni, Stefano, Gambelli, Elena, Provinciali, Leandro, Carriero, Alessandro, Coppo, Lorenzo, Baldan, Julika, Paolo Nuzzi, Nunzio, Marcheselli, Simona, Corato, Manuel, Cotroneo, Enrico, Ricciardi, Fabrizio, Gigli, Renato, Pozzessere, Claudio, Pezzella, Francesca Romana, Corsi, Fabio, Squassina, Guido, Cobelli, Milena, Morassi, Mauro, Magni, Eugenio, Pepe, Fulvio, Bigni, Barbara, Costa, Paolo, Crabbio, Massimo, Griffini, Simona, Palmerini, Francesco, Piras, Maria Paola, Natrella, Massimiliano, Fanelli, Gianluca, Cristoferi, Massimo, Bottacchi, Edo, Corso, Giovanni, Tosi, Piera, Amistà, Pietro, Russo, Monia, Tettoni, Serena, Gallesio, Ivan, Mascolo, Maria Carmela, Meloni, Giovanni Battista, Fabio, Claudio, Maiore, Mario, Pintus, Francesco, Pischedda, Aldo, Manca, Antonio, Mongili, Claudia, Zanda, Bastianina, Sanna, Antonella, Baule, Antonio, Pappalardo, Maria Pia, Craparo, Giuseppe, Gallo, Cristina, Monaco, Serena, Mannino, Marina, Terruso, Valeria, Muto, Mario, Guarnieri, Gianluigi, Andreone, Vincenzo, Dui, Giovanni, Ticca, Anna, Salmaggi, Andrea, Iannucci, Giuseppe, Pinna, Vittore, Di Clemente, Loris, Perini, Francesco, De Boni, Antonella, De Luca, Cristina, De Giorgi, Franco, Corraine, Simona, Enne, Paolo, Ganau, Claudio, and Piras, Valeria

Subjects
Male, medicine.medical_specialty, Fibrinolytic Agents/therapeutic use Humans Male Middle Aged *Nomograms Postoperative Complications/etiology Risk Assessment Risk Factors Stroke/complications/drug therapy/*surgery Thrombectomy/*adverse effects Thrombolytic Therapy/adverse effects, medicine.medical_treatment, contraindications, Risk Assessment, NO, Brain Ischemia, Brain ischemia, Postoperative Complications, Fibrinolytic Agents, Risk Factors, contraindications ◼ logistic models ◼ nomograms ◼ standard of care ◼ thrombectomy, medicine, 80 and over, Humans, Thrombolytic Therapy, Stroke, contraindications, logistic models, nomograms, standard of care, thrombectomy, Aged, Cerebral Hemorrhage, Aged, 80 and over, Advanced and Specialized Nursing, Intracerebral hemorrhage, Receiver operating characteristic, business.industry, Thrombolysis, Nomogram, Middle Aged, medicine.disease, logistic models, nomograms, standard of care, thrombectomy, Female, Thrombectomy, Tissue Plasminogen Activator, Nomograms, Settore MED/26 - NEUROLOGIA, Neurology (clinical), Radiology, Cardiology and Cardiovascular Medicine, business, Fibrinolytic agent, Cohort study
Abstract

Background and Purpose— As a reliable scoring system to detect the risk of symptomatic intracerebral hemorrhage after thrombectomy for ischemic stroke is not yet available, we developed a nomogram for predicting symptomatic intracerebral hemorrhage in patients with large vessel occlusion in the anterior circulation who received bridging of thrombectomy with intravenous thrombolysis (training set), and to validate the model by using a cohort of patients treated with direct thrombectomy (test set). Methods— We conducted a cohort study on prospectively collected data from 3714 patients enrolled in the IER (Italian Registry of Endovascular Stroke Treatment in Acute Stroke). Symptomatic intracerebral hemorrhage was defined as any type of intracerebral hemorrhage with increase of ≥4 National Institutes of Health Stroke Scale score points from baseline ≤24 hours or death. Based on multivariate logistic models, the nomogram was generated. We assessed the discriminative performance by using the area under the receiver operating characteristic curve. Results— National Institutes of Health Stroke Scale score, onset-to-end procedure time, age, unsuccessful recanalization, and Careggi collateral score composed the IER-SICH nomogram. After removing Careggi collateral score from the first model, a second model including Alberta Stroke Program Early CT Score was developed. The area under the receiver operating characteristic curve of the IER-SICH nomogram was 0.778 in the training set (n=492) and 0.709 in the test set (n=399). The area under the receiver operating characteristic curve of the second model was 0.733 in the training set (n=988) and 0.685 in the test set (n=779). Conclusions— The IER-SICH nomogram is the first model developed and validated for predicting symptomatic intracerebral hemorrhage after thrombectomy. It may provide indications on early identification of patients for more or less postprocedural intensive management.

Published
2019

40. Caregiver burden predicting factors in Alzheimer's disease

Author

Brigandì, Amelia, Buccafusca, Maria, Casella, Carmela, Cotroneo, Masina, Frosina, Luciano, Grillo, Francesco, Dell'Aera, Cristina, Raffaele, Massimo, and Tomasello, Letteria

Subjects
BPSD, Alzheimer's disease, Caregiver burden, Caregiver burden, Alzheimer's disease, BPSD
Published
2018

42. Acute Stroke Treatment in Patients with Basilar Artery Occlusion: A Single-Center Observational Study

Author

Francalanza, Isabella, primary, Ciacciarelli, Antonio, additional, Caragliano, Antonio Armando, additional, Casella, Carmela, additional, Cotroneo, Masina, additional, Dell’Aera, Cristina, additional, Fazio, Maria Carolina, additional, Grillo, Francesco, additional, Pitrone, Antonio, additional, Vinci, Sergio Lucio, additional, Trimarchi, Giuseppe, additional, Musolino, Rosa Fortunata, additional, and La Spina, Paolino, additional

Published
2019
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48. Bridging the Gap Towards Awareness Detection in Disorders of Consciousness: An Experimental Study on the Mirror Neuron System

Author

Naro, Antonino, primary, Calabrò, Rocco Salvatore, additional, Leo, Antonino, additional, Russo, Margherita, additional, Milardi, Demetrio, additional, Cannavò, Antonino, additional, Manuli, Alfredo, additional, Buda, Antonio, additional, Casella, Carmela, additional, Bramanti, Placido, additional, Cacciola, Alberto, additional, and Bramanti, Alessia, additional

Published
2018
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49. Agenesis of the Internal Carotid Artery Associated with Generalized Epilepsy

Author

La Spina, Paolino, primary, Grillo, Francesco, additional, Granata, Francesca, additional, Casella, Carmela, additional, Fazio, Maria Carolina, additional, Colella, Margherita, additional, Cotroneo, Masina, additional, Dell'Aera, Cristina, additional, Ciacciarelli, Antonio, additional, Vita, Giuseppe, additional, and Musolino, Rosa, additional

Published
2018
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