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1. Improving crunchiness and crispness of fried squid rings through innovative tempura coatings: addition of alcohol and CO2 incubation

Author: Carvalho, MJ and Ruiz-Carrascal, J.
Published: 2018
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2. Worldwide trends in diabetes since 1980: a pooled analysis of 751 population-based studies with 4·4 million participants

Author: Zhou, B, Lu, Y, Hajifathalian, K, Bentham, J, Di Cesare, M, Danaei, G, Bixby, H, Cowan, MJ, Ali, MK, Taddei, C, Lo, WC, Reis-Santos, B, Stevens, GA, Riley, LM, Miranda, JJ, Bjerregaard, P, Rivera, JA, Fouad, HM, Ma, G, Mbanya, JC, McGarvey, ST, Mohan, V, Onat, A, Pilav, A, Ramachandran, A, Romdhane, HB, Paciorek, CJ, Bennett, JE, Ezzati, M, Abdeen, ZA, Abdul Kadir, K, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, R, Aekplakorn, W, Aguilar-Salinas, CA, Agyemang, C, Ahmadvand, A, Al-Othman, AR, Alkerwi, A, Amouyel, P, Amuzu, A, Andersen, LB, Anderssen, SA, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicová, M, Azizi, F, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barceló, A, Batieha, AM, Baur, LA, Benet, M, Bernabe-Ortiz, A, Bharadwaj, S, Bhargava, SK, Bi, Y, Bjertness, E, Bjertness, MB, Björkelund, C, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Bovet, P, Brajkovich, I, Breckenkamp, J, Brenner, H, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, Cabrera de León, A, Can, G, Cândido, AP, Capuano, V, Carlsson, AC, Carvalho, MJ, Casanueva, FF, Casas, JP, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, CJ, Chen, F, Chen, S, Cheng, CY, Chetrit, A, Chiou, ST, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Deschamps, V, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Dzerve, V, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, Escobedo-de la Peña, J, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernández-Bergés, D, Ferrari, M, Ferreccio, C, Feskens, EJ, Finn, JD, Föger, B, Foo, LH, Forslund, AS, Francis, DK, Franco Mdo, C, Franco, OH, Frontera, G, Furusawa, T, Gaciong, Z, Garnett, SP, Gaspoz, JM, Gasull, M, Gates, L, Geleijnse, JM, Ghasemian, A, Ghimire, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Giwercman, A, Gross, MG, González Rivas, JP, Gorbea, MB, Gottrand, F, Grafnetter, D, Grodzicki, T, Grøntved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hambleton, IR, Hardy, R, Hari Kumar, R, Hata, J, He, J, Heidemann, C, Herrala, S, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Hormiga, CM, Horta, BL, Houti, L, Howitt, C, Htay, TT, Htet, AS, Htike, MM, Hu, Y, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jamil, KM, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Keinänen-Kiukaanniemi, S, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Khalili, D, Khang, YH, Kiechl, S, Kim, J, Kolsteren, P, Korrovits, P, Kratzer, W, Kromhout, D, Kujala, UM, Kula, K, Kyobutungi, C, Laatikainen, T, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimäki, T, Lekhraj, R, León-Muñoz, LM, Li, Y, Lim, WY, Lima-Costa, MF, Lin, HH, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Luksiene, D, Lundqvist, A, Lytsy, P, Machado-Coelho, GL, Machi, S, Maggi, S, Magliano, DJ, Makdisse, M, Mallikharjuna Rao, K, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Mathiesen, EB, Matsha, TE, McFarlane, SR, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AM, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohammadifard, N, Mohd Yusoff, MF, Møller, NC, Molnár, D, Mondo, CK, Morejon, A, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Motta, J, Mu, TT, Muiesan, ML, Müller-Nurasyid, M, Mursu, J, Nagel, G, Námešná, J, Nang, EE, NangThetia, VB, Navarrete-Muñoz, EM, Ndiaye, NC, Nenko, I, Nervi, F, Nguyen, ND, Nguyen, QN, Nieto-Martínez, RE, Ning, G, Ninomiya, T, Noale, M, Noto, D, Nsour, MA, Ochoa-Avilés, AM, Oh, K, Ordunez, P, Osmond, C, Otero, JA, Owusu-Dabo, E, Pahomova, E, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pelletier, C, Peltonen, M, Peters, A, Peykari, N, Pham, ST, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubió, P, Porta, M, Portegies, ML, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Radisauskas, R, Rahman, M, Raitakari, O, Rao, SR, Ramke, J, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PF, Rigo, F, Robinson, SM, Robitaille, C, Rodríguez-Artalejo, F, Rodriguez-Perez Mdel, C, Rodríguez-Villamizar, LA, Rojas-Martinez, R, Ronkainen, K, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Russo Horimoto, RV, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sánchez-Abanto, J, Santos, D, dos Santos, RN, Santos, R, Saramies, JL, Sardinha, LB, Sarrafzadegan, N, Saum, KU, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Sein, AA, Sharma, SK, Shaw, JE, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, So, HK, Sobngwi, E, Söderberg, S, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Stathopoulou, MG, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stöckl, D, Stokwiszewski, J, Stronks, K, Strufaldi, MW, Sun, CA, Sundström, J, Sung, YT, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tamosiunas, A, Tang, L, Tarawneh, M, Tarqui-Mamani, CB, Taylor, A, Theobald, H, Thijs, L, Thuesen, BH, Tolonen, HK, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OT, Tulloch-Reid, MK, Tuomainen, TP, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FA, Ulmer, H, Uusitalo, HM, Valdivia, G, Valvi, D, van Rossem, L, van Valkengoed, IG, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, WM, Verstraeten, R, Viet, L, Vioque, J, Virtanen, JK, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Vrijheid, M, Wade, AN, Wagner, A, Walton, J, Wan Mohamud, WN, Wang, F, Wang, MD, Wang, Q, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wijga, AH, Wilks, RJ, Willeit, J, Wilsgaard, T, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, FC, Wu, SL, Xu, H, Yan, W, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, Zheng, Y, and Zuñiga Cisneros, J
Published: 2016
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3. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331 288 participants

Author: Danaei, G, Fahimi, S, Lu, Y, Zhou, B, Hajifathalian, K, Di Cesare, M, Lo, WC, Reis-Santos, B, Cowan, MJ, Shaw, JE, Bentham, J, Lin, JK, Bixby, H, Magliano, D, Bovet, P, Miranda, JJ, Khang, YH, Stevens, GA, Riley, LM, Ali, MK, Ezzati, M, Abdeen, ZA, Kadir, KA, Abu-Rmeileh, M, Acosta-Cazares, B, Aekplakorn, W, Aguilar-Salinas, CA, Ahmadvand, A, Al Nsour, M, Alkerwi, A, Amouyel, P, Andersen, LB, Anderssen, SA, Andrade, DS, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicová, M, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barceló, A, Batieha, AM, Baur, LA, Ben Romdhane, H, Bernabe-Ortiz, A, Bhargava, SK, Bi, Y, Bjerregaard, P, Björkelund, C, Blake, M, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Brajkovich, I, Breckenkamp, J, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, Cabrera de León, A, Can, G, Cândido, AP, Capuano, V, Carvalho, MJ, Casanueva, FF, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, CJ, Chen, F, Chen, S, Cheng, CY, Chetrit, A, Chiou, ST, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, Escobedo-de la Peña, J, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernández-Bergés, D, Ferrari, M, Ferreccio, C, Finn, JD, Föger, B, Foo, LH, Fouad, HM, Francis, DK, Franco Mdo, C, Frontera, G, Furusawa, T, Gaciong, Z, Galbarczyk, A, Garnett, SP, Gaspoz, JM, Gasull, M, Gates, L, Geleijnse, JM, Ghasemain, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Gonzalez Gross, M, González Rivas, JP, Gorbea, MB, Gottrand, F, Grant, JF, Grodzicki, T, Grøntved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hardy, R, Hari Kumar, R, Heidemann, C, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Horimoto, AR, Hormiga, CM, Horta, BL, Houti, L, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Kiechl, S, Kim, J, Kiyohara, Y, Kolsteren, P, Korrovits, P, Koskinen, S, Kratzer, W, Kromhout, D, Kula, K, Kurjata, P, Kyobutungi, C, Lachat, C, Laid, Y, Lam, TH, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimäki, T, Lekhraj, R, León-Muñoz, LM, Li, Y, Lim, WY, Lima-Costa, MF, Lin, HH, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Lundqvist, A, Lytsy, P, Ma, G, Machado-Coelho, GL, Machi, S, Maggi, S, Makdisse, M, Mallikharjuna v, K, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Matsha, TE, Mbanya, JC, McFarlane, SR, McGarvey, ST, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AM, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohan, V, Mohd Yusoff, MF, Møller, NC, Molnar, D, Mondo, CK, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Muiesan, ML, Müller-Nurasyid, M, Mursu, J, Nagel, G, Námešná, J, Nang, EE, Nangia, VB, Navarrete-Muñoz, EM, Ndiaye, NC, Nervi, F, Nguyen, ND, Nieto-Martínez, RE, Alvarado, L, Ning, G, Ninomiya, T, Noale, M, Noto, D, Ochoa-Avilés, M, Oh, K, Onat, A, Osmond, C, Otero, JA, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pereira, AC, Peters, A, Peykari, N, Pilav, A, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubió, P, Porta, M, Portegies, ML, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Raitakari, O, Ramachandra Rao, S, Ramachandran, A, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PF, Rigo, F, Robinson, SM, Robitaille, C, Rodríguez, LA, Rodríguez-Artalejo, F, del Cristo Rodriguez-Perez, M, Rojas-Martinez, R, Romaguera, D, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sánchez-Abanto, J, Santos, RN, Santos, R, Sardinha, LB, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stöckl, D, Stokwiszewski, J, Strufaldi, MW, Sun, CA, Sundström, J, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tarawneh, M, Tarqui-Mamani, CB, Thijs, L, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OT, Tulloch-Reid, MK, Tuomainen, TP, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FM, Ulmer, H, Valdivia, G, van Valkengoed, IG, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, M, Vioque, J, Virtanen, J, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Wade, AN, Wagner, A, Walton, J, Mohamud, WN, Wang, MD, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wilks, RJ, Willeit, J, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, AG, Wu, FC, Wu, SL, Xu, H, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, and Zheng, Y
Published: 2015
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4. Trends and challenges in the Portuguese penitentiary system: from law to practice

Author: Gomes, S, Leote De Carvalho, MJ, Oliveira, RV, and Duarte, V
Abstract: This article focuses on the trends and challenges faced by the Portuguese penitentiary system between 2000 and 2017, taking into account the Portuguese Penal Law, penal statistics, national and international reports, and studies regarding the Portuguese prison system. The description of the changes in the Penal Law helps us to understand, on one hand, the changes in penal statistics over time and, on the other hand, the inconsistencies between the law in books and law in practice.
Published: 2018

5. Worldwide trends in body-mass index, underweight, overweight, and obesity from 1975 to 2016: a pooled analysis of 2416 population-based measurement studies in 128.9 million children, adolescents, and adults

Author: Ezzati, M, Bentham, J, Di Cesare, M, Bilano, V, Bixby, H, Zhou, B, Stevens, GA, Riley, LM, Taddei, C, Hajifathalian, K, Lu, Y, Savin, S, Cowan, MJ, Paciore, CJ, Chiritaemandi, A, Hayes, AJ, Katz, J, Kelishadi, R, Kengne, AP, Khang, Y-H, Laxmaiah, A, Li, Y, Ma, J, Miranda, JJ, Mostafa, A, Neovius, M, Padez, C, Rampal, L, Zhu, A, Bennet, JE, Danaei, G, Bhutta, ZA, Abarca-Gomez, L, Abdeen, ZA, Hamid, ZA, Abu-Rmeileh, NM, Acosta-Cazares, B, Acuin, C, Adams, RJ, Aekplakorn, W, Afsana, K, Aguilar-Salinas, CA, Agyemng, C, Ahmadvand, A, Ahrens, W, Ajlouni, K, Akhtaeva, N, Al-Hazzaa, HM, Al-Othman, AR, Al-Raddadi, R, AlBuhairan, F, AlDhukai, S, Ali, MM, Ali, O, Alkerwi, A, Alvarez-Pedrerol, M, Aly, E, Amarapurkar, DN, Amouyel, P, Amuzu, A, Andersen, LB, Anderssen, SA, Andrade, DS, Angquist, LH, Anjana, RM, Aounallah-Skhiri, H, Araujo, J, Arianse, I, Aris, T, Arlappa, N, Arveiler, D, Aryal, KK, Aspelund, T, Assah, FK, Assuncao, MCF, Aung, MS, Avdicova, M, Azevedo, A, Azizi, F, Babu, BV, Bahijri, S, Baker, JL, Balakrishna, N, Bamoshmoosh, M, Banach, M, Bandosz, P, Banegas, JR, Barbagallo, CM, Barcelo, A, Barkat, A, Barros, AJD, Barros, MVG, Bata, I, Batieha, AM, Batista, RL, Batyrbek, A, Baur, LA, Beaglehole, R, Ben Romdhane, H, Benedics, J, Benet, M, Bernabe, A, Bernotiene, G, Bettiol, H, Bhagyalaxmi, A, Bharadwaj, S, Bhargava, SK, Bhatti, Z, Bi, H, Bi, Y, Biehl, A, Bikbov, M, Bista, B, Bjelica, DJ, Bjerregaard, P, Bjertnes, E, Bjness, MB, Bjorkelund, C, Blokstra, A, Bo, S, Bobak, M, Boddy, LM, Boehm, BO, Boeing, H, Boggia, JG, Boissonnet, CP, Bonaccio, M, Bongard, V, Bovet, P, Braeckevelt, L, Braeckman, L, Bragt, MCE, Brajkovich, I, Branca, F, Breckenkamp, J, Breda, J, Brenner, H, Brewster, LM, Brian, GR, Brinduse, L, Bruno, G, Bueno-de-Mesquita, HB, Bugge, A, Buoncristiano, M, Burazeri, G, Burns, C, Cabrera de Leon, A, Cacciottolo, J, Cai, H, Cama, T, Cameron, C, Camola, J, Can, G, Candido, APCC, Capanzana, M, Capuano, V, Cardoso, VC, Carlsson, AC, Carvalho, MJ, Casanueva, FF, Casas, JP, Caserta, CA, Chamukuttan, S, Chan, AW, Chan, Q, Chaturvedi, HK, Chaturvedi, N, Chen, C-J, Chen, F, Chen, H, Chen, S, Chen, Z, Cheng, C-Y, Chetrit, A, Chikova-Iscener, E, Chiolero, A, Chiou, S-T, Chirita-Emandi, A, Chirlaque, M-D, Cho, B, Cho, Y, Christensen, K, Christofaro, DG, Chudek, J, Cifkova, R, Cinteza, E, Claessens, F, Clays, E, Concin, H, Confortin, SC, Cooper, C, Cooper, R, Coppinger, TC, Costanzo, S, Cottel, D, Cowell, C, Craig, CL, Crujeiras, AB, Cucu, A, D'Arrigo, G, d'Orsi, E, Dallongeville, J, Damasceno, A, Damsgaard, CT, Danae, G, Dankner, R, Dantoft, TM, Dastgiri, S, Dauchet, L, Davletov, K, De Backer, G, De Bacquer, D, De Curtis, A, de Gaetano, G, De Henauw, S, de Oliveira, PD, De Ridder, K, De Smedt, D, Deepa, M, Deev, AD, Dehghan, A, Delisle, H, Delpeuch, F, Deschamps, V, Dhana, K, Di Castelnuovo, AF, Dias-da-Costa, JS, Diaz, A, Dika, Z, Djalalinia, S, Do, HTP, Dobson, AJ, Donati, MB, Donfrancesco, C, Donoso, SP, Doering, A, Dorobantu, M, Dorosty, AR, Doua, K, Drygas, W, Duan, JL, Duante, C, Duleva, V, Dulskiene, V, Dzerve, V, Dziankowska-Zaborszczyk, E, Egbagbe, EE, Eggertsen, R, Eiben, G, Ekelund, U, El Ati, J, Elliott, P, Engle-Stone, R, Erasmus, RT, Erem, C, Eriksen, L, Eriksson, JG, Escobedo, J, Evans, A, Faeh, D, Fall, CH, Sant'Angelo, VF, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernandes, RA, Fernandez-Berges, D, Ferrante, D, Ferrari, M, Ferreccio, C, Ferrieres, J, Finn, JD, Fischer, K, Monterubio Flores, E, Foeger, B, Foo, LH, Forslund, A-S, Forsner, M, Fouad, HM, Francis, DK, Franco, MDC, Franco, OH, Frontera, G, Fuchs, FD, Fuch, SC, Fujita, Y, Furusawa, T, Gaciong, Z, Gafencu, M, Galeone, D, Galvano, F, Garcia-de-la-Hera, M, Gareta, D, Garnett, SP, Gaspoz, J-M, Gasull, M, Gates, L, Geiger, H, Geleijnse, JM, Ghasemian, A, Giampaoli, S, Gianfagna, F, Gill, TK, Giovannelli, J, Giwerman, A, Godos, J, Gogen, S, Goldsmith, RA, Goltzman, D, Goncalves, H, Gonzalez-Leon, M, Gonzalez-Rivas, JP, Gonzalez-Gross, M, 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Univ Med Sci, BRAC, Inst Epidemiol Dis Control & Res, Univ Turku, Univ New South Wales, Inst Univ Invest Atencio Primaria Jordi Gol, Univ Malaya, Univ Valencia, Univ Philippines, Nutr Res Fdn, Minas Gerais State Secretariat Hlth, Hlth Ctr San Agustin, PharmAccess Fdn, Natl Inst Hlth Doutor Ricardo Jorge, Publ Hlth Agcy Canada, Canarian Hlth Serv, Univ Ind Santander, Gothenburg Univ, Fiji Natl Univ, Sitaram Bhartia Inst Sci & Res, Univ Tunis El Mana, Univ Helsinki, Natl Inst Hlth Peru, Catalan Dept Hlth, Publ Hlth Subdelegate Off, Univ Lisbon, Prevent Med & Publ Hlth, South Karelia Social & Hlth Care Dist, Isfahan Cardiovasc Res Ctr, Hosp Italiano Buenos Aires, Rigshosp, Lagos State Univ, Univ Las Palmas Gran Canaria, Baker Heart and Diabet Inst, Univ Tokyo, Samsung Med Ctr, Finnish Inst Occupat Hlth, St Vincents Hosp, Acad Med Ctr Amsterdam, Hlth Polytech Jakarta II Inst, Univ Bari, Inst Reg Sante Publ, Univ Bordeaux, Inst Publ Hlth Republ Macedonia, Univ Leuven, Lamprecht & Stamm Sozialforsch & Beratung AG, Univ Bonn, Sotiria Hosp, Swansea Univ, Fu Jen Catholic Univ, Natl Inst Hlth, UNICEF, Danish Canc Soc Res Ctr, Hlth Serv Murcia, Res & Educ Inst, IB SALUT Area Salut Menorca, Univ Bologna, Hellen Hlth Fdn, Univ Pharm & Med Ho Chi Min City, Governm Med Coll, Sefako Makgatho Hlth Sci Univ, Addis Ababa Univ, Dasman Diabet Inst, Hellen Med Associat Obes, Univ Ctr Occidental Lisandro Alvarado, Meharry Med Coll, Dokuz Eylul Univ, Univ Tampere, Polytech Inst Porto, Univ Utrecht, Amsterdam Publ Hlth Res Inst, Universidade Federal de Minas Gerais (UFMG), Fed Univ Pelota, Italian Natl Res Council, Univ Miguel Hernandez, North Karelian Ctr Publ Hlth, ISGlobal Ctr Res Environm Epidemiol, Univ Witwatersrand, Med Univ Vienna, Univ Coll Cork, Inst Med Res, Xinjiang Med Univ, St Georges Univ London, Univ Indonesia, Natl Inst Hyg, Univ Mancheste, Kailuan Gen Hosp, Minist Agr, Fudan Univ, Chinese Ctr Dis Control & Prevent, Univ Cyprus, Univ Teknol MARA, Capital Med Univ Beijing, West Kazakhstan State Med Univ, Inner Mongolia Med Univ, Gorgas Mem Inst Publ Hlth, Internal Medicine, Epidemiology, Erasmus MC other, Pediatrics, Public Health, and Clinical Genetics
Subjects: SDG 3 - Good Health and Well-being, Medicine (all)
Abstract: Made available in DSpace on 2018-11-26T20:04:45Z (GMT). No. of bitstreams: 0 Previous issue date: 2017-12-16 Wellcome Trust AstraZeneca Background Underweight, overweight, and obesity in childhood and adolescence are associated with adverse health consequences throughout the life-course. Our aim was to estimate worldwide trends in mean body-mass index (BMI) and a comprehensive set of BMI categories that cover underweight to obesity in children and adolescents, and to compare trends with those of adults. Methods We pooled 2416 population-based studies with measurements of height and weight on 128.9 million participants aged 5 years and older, including 31.5 million aged 5-19 years. We used a Bayesian hierarchical model to estimate trends from 1975 to 2016 in 200 countries for mean BMI and for prevalence of BMI in the following categories for children and adolescents aged 5-19 years: more than 2 SD below the median of the WHO growth reference for children and adolescents (referred to as moderate and severe underweight hereafter), 2 SD to more than 1 SD below the median (mild underweight), 1 SD below the median to 1 SD above the median (healthy weight), more than 1 SD to 2 SD above the median (overweight but not obese), and more than 2 SD above the median (obesity). Findings Regional change in age-standardised mean BMI in girls from 1975 to 2016 ranged from virtually no change (-0.01 kg/m (2) per decade; 95% credible interval -0.42 to 0.39, posterior probability [PP] of the observed decrease being a true decrease= 0.5098) in eastern Europe to an increase of 1.00 kg/m(2) per decade (0.69-1.35, PP> 0.9999) in central Latin America and an increase of 0.95 kg/m (2) per decade (0.64-1.25, PP> 0.9999) in Polynesia and Micronesia. The range for boys was from a non-significant increase of 0.09 kg/m(2) per decade (-0.33 to 0.49, PP= 0.6926) in eastern Europe to an increase of 0.77 kg/m (2) per decade (0.50-1.06, PP> 0.9999) in Polynesia and Micronesia. Trends in mean BMI have recently flattened in northwestern Europe and the high-income English-speaking and Asia-Pacific regions for both sexes, southwestern Europe for boys, and central and Andean Latin America for girls. By contrast, the rise in BMI has accelerated in east and south Asia for both sexes, and southeast Asia for boys. Global age-standardised prevalence of obesity increased from 0.7% (0.4-1.2) in 1975 to 5.6% (4.8-6.5) in 2016 in girls, and from 0.9% (0.5-1.3) in 1975 to 7.8% (6.7-9.1) in 2016 in boys; the prevalence of moderate and severe underweight decreased from 9.2% (6.0-12.9) in 1975 to 8.4% (6.8-10.1) in 2016 in girls and from 14.8% (10.4-19.5) in 1975 to 12.4% (10.3-14.5) in 2016 in boys. Prevalence of moderate and severe underweight was highest in India, at 22.7% (16.7-29.6) among girls and 30.7% (23.5-38.0) among boys. Prevalence of obesity was more than 30% in girls in Nauru, the Cook Islands, and Palau; and boys in the Cook Islands, Nauru, Palau, Niue, and American Samoa in 2016. Prevalence of obesity was about 20% or more in several countries in Polynesia and Micronesia, the Middle East and north Africa, the Caribbean, and the USA. In 2016, 75 (44-117) million girls and 117 (70-178) million boys worldwide were moderately or severely underweight. In the same year, 50 (24-89) million girls and 74 (39-125) million boys worldwide were obese. Interpretation The rising trends in children's and adolescents' BMI have plateaued in many high-income countries, albeit at high levels, but have accelerated in parts of Asia, with trends no longer correlated with those of adults. 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Rica Al Quds Univ, Jerusalem, Palestine Ctr Diabet & Endocrine Care, Bengaluru, India Birzeit Univ, Birzeit, Palestine Inst Mexicano Seguro Social, Mexico City, DF, Mexico Int Rice Res Inst, Los Banos, Philippines Univ Adelaide, Adelaide, SA, Australia Mahidol Univ, Salaya, Nakhon Pathom, Thailand BARC, Dhaka, Bangladesh Inst Nacl Ciencias Med & Nutr Salvador Zubiran, Mexico City, DF, Mexico Univ Amsterdam, Amsterdam, Netherlands Noncommun Dis Res Ctr, Tehran, Iran Leibniz Inst Prevent Res & Epidemiol BIPS, Leipzig, Germany Natl Ctr Diabet Endocrinol, Amman, Jordan Kazakh Natl Med Univ, Alma Ata, Kazakhstan King Saud Univ, Riyadh, Saudi Arabia Kuwait Inst Sci Res, Kuwait, Kuwait Minist Hlth, Riyadh, Saudi Arabia King Abdullah Int Med Res Ctr, Riyadh, Saudi Arabia Univ Malaysia Sabah, Kota Kinabalu, Malaysia Luxembourg Inst Hlth, Luxembourg, Luxembourg ISGlobal Ctr Res Environm Epidemol, Barcelona, Spain WHO, Reg Off Eastern Mediterranean, Cairo, Egypt Bombay Hosp & Med Res Ctr, Bombay, Maharashtra, India Lille Univ & Hosp, Lille, France London Sch Hyg & Trop Med, London, England Western Norway Univ App Sci, Bergen, Norway Norwegian Sch Sport Sci, Oslo, Norway Univ Cuenca, Cuenca, Ecuador Bispebjerg Hosp, Copenhagen, Denmark Frederiksberg Univ Hosp, Copenhagen, Denmark Madras Diabet Res Fdn, Madras, Tamil Nadu, India Natl Inst Publ Hlth, Tunis, Tunisia Univ Porto, Oporto, Portugal Norwegian Inst Publ Hlth, Oslo, Norway Minist Hlth Malaysia, Putrajaya, Malaysia Natl Inst Nutr, Bangalore, Karnataka, India Univ Strasbourg, Strasbourg, France Strasbourg Univ Hosp, Strasbourg, France Nepal Hlth Res Council, Kathmandu, Nepal Univ Iceland, Reykjavik, Iceland Univ Yaounde, Yaounde, Cameroon Univ Fed Pelotas, Pelotas, Brazil Univ Med, Yangon, Myanmar Univ Porto, Med Sch, Oporto, Portugal Shahid Beheshti Univ Med Sci, Tehran, Iran Indian Council Med Res, New Delhi, India King Abdulaziz Univ, Riyadh, Saudi Arabia Univ Sci & Technol, Taizi, Yemen Med Univ Lodz, Lodz, Poland Med Univ Gdansk, Gdansk, Poland Univ Autonoma Madrid, Madrid, Spain Univ Palermo, Palermo, Italy Pan Amer Hlth Org, Washington, DC USA Mohammed V Univ Rabat, Rabat, Morocco Univ Pernambuco, Recife, PE, Brazil Dalhousie Univ, Calgary, AB, Canada Jordan Univ Technol, Amman, Jordan Univ Fed Maranhao, Sao Luis, Brazil Univ Auckland, Auckland, New Zealand Univ Tunis El Manar, El Manar, Tunisia Fed Minist Hlth & Womens Affairs, Vienna, Austria CAFAM Univ Fdn, Bogota, Colombia Imperial Coll London, London, England Lithuanian Univ Hlth Sci, Kaunas, Lithuania Univ Sao Paulo, Sao Paulo, Brazil BJ Med Coll, Pune, Maharashtra, India Chirayu Med Coll, Bhopal, India Sunder Lal Jain Hosp, Delhi, India Shandong Univ Tradit Chinese Med, Shanghai, Peoples R China Shanghai Jiao Tong Univ, Sch Med, Shanghai, Peoples R China Norwegian Inst Publ, Oslo, Norway Ufa Eye Res Inst, Moscow, Russia Univ Montenegro, Montenegro, Mexico Univ Southern Denmark, Lyngby, Denmark Univ Oslo, Oslo, Norway Univ Gothenburg, 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Technol, Cork, Ireland Univ La Laguna, San Cristobal la Laguna, Spain Univ Malta, Msida, Malta Vanderbilt Univ, 221 Kirkland Hall, Nashville, TN 37235 USA Minist Hlth, Pangai, Tonga Canadian Fitness & Lifestyle Res Inst, Ottawa, ON, Canada Hosp Santa Maria, Lisbon, Portugal Istanbul Univ, Istanbul, Turkey Univ Fed Juiz de Fora, Juiz De Fora, Portugal Food & Nutr Res Inst, Manila, Philippines Santiago de Compostela Univ, Santiago De Compostela, Spain Assoc Calabrese Epatol, Perugia, Italy India Diabet Res Fdn, Delhi, India Duke NUS Med Sch, Singapore, Singapore Natl Inst Med Stat, New Delhi, India Acad Sinica, Taipei, Taiwan Capital Inst Pediat, Beijing, Peoples R China Duke Univ, Durham, NC 27706 USA Kailuan General Hospital, Tangshan, Peoples R China Univ Oxford, Oxford, England Duke NUS MEd Sch, Singapore, Singapore Gertner Inst Epidemiol & Hlth Policy Res, Tel Aviv, Israel Natl Ctr Publ Hlth & Anal, Sofia, Bulgaria Univ Bern, Bern, Switzerland Minist Hlth & Welfare, Taipei, Taiwan Murcia Reg Hlth Council, Murcia, Spain Seoul Natl Univ, Coll Med, Seoul, South Korea Korea Ctr Dis Control & Prevent, Seoul, South Korea Univ Estadual Paulista, Sao Paulo, Brazil Med Univ Silesia, Katowice, Poland Charles Univ Prague, Prague, Czech Republic Katholieke Univ Leuven, Leuven, Belgium Agcy Prevent & Social Med, Vienna, Austria Univ Fed Santa Catarina, Sao Carlos, SP, Brazil Univ Southampton, Southampton, Hants, England Inst Pasteur, Lille, France CIBEROBN, Barcelona, Spain Natl Inst Publ Hlth, Bucharest, Romania Natl Council Res, Rome, Italy Univ Fed Santa Catarin, Sao Carlos, SP, Brazil Eduardo Mondlane Univ, Maputo, Mozambique Univ Copenhagen, Copenhagen, Denmark Res Ctr Prevent & Hlth, Glostrup, Denmark Tabriz Hlth Serv Managemnet Ctr, Tabriz, Iran Lille Univ Hosp, Lille, France Sci Inst Publ Hlth, Brussels, Belgium Madaras Diabet Res Fdn, Chennai, India Natl Res Ctr Prevent Med, Moscow, Russia Erasmus MC, Rotterdam, Netherlands Univ Montreal, Montreal, PQ, Canada Inst Rech Dev, Montpellier, France French Publ Hlth Agcy, St Maurice, France Univ Vale Rio Sino, Sao Leopoldo, Brazil Natl Council Sci & Tech Res, Buenos Aires, DF, Argentina Univ Zagreb, Zagreb, Croatia Univ Tehran Med Sci, Tehran, Iran Natl Inst Nutr, Hanoi, Vietnam Univ Queensland, Brisbane, Qld, Australia Ist Super Sanita, Rome, Italy Helmholtz Zentrum Munchen, Munich, Germany Minist Sante & Lutte Contre Sida, Abidjan, Cote Ivoire Cardinal Wyszynski Inst Cardiol, Warsaw, Poland Beijing Ctr Dis Prevent & Control, Beijing, Peoples R China Univ Latvia, Riga, Latvia Univ Benin, Benin, Nigeria Univ Skovde, Skovde, Sweden Natl Inst Nutr & Food Technol, Tunis, Tunisia Univ Calif Davis, Davis, CA 95616 USA Univ Stellenbosch, Stellenbosch, South Africa Karadeniz Tech Univ, Trabzon, Turkey Univ Southern Copenhagen, Copenhagen, Denmark Natl Inst Hlth & Welfare, Helsinki, Finland Queens Univ Belfast, Belfast, Antrim, North Ireland Univ Zurich, Zurich, Switzerland Primary Health Care, Floriana, Malta Ctr Salud Villanueva Norte, Villanueva De La Serena, Spain Univ West Indies, Mona, Jamaica Hosp Don Benito Villanueva de la Serena, Villanueva De La Serena, Spain Minist Hlth, Buenos Aires, DF, Argentina Council Agr Res & Econ, Rome, Italy Pontificia Univ Catolica Chile, Santiago, Chile Univ Toulouse, Sch Med, Toulouse, France Univ Manchester, Manchester, Lancs, England Univ Tartu, Tartu, Estonia Inst Nacl Salud Publ, Cuernavaca, Morelos, Mexico Univ Sains Malaysia, George Town, Malaysia Umea Univ, Umea, Sweden Dalarna University, Falun, Sweden Univ West Indies, Kingston, Jamaica Univ Fed Sao Paulo, Sao Paulo, Brazil Hosp Univ Son Espases, Palma De Mallorca, Spain Hosp Clin Porto Alegre, Porto Alegre, RS, Brazil Univ Fed Rio Grande do Sul, Rio Grande, Brazil Kindai Univ, Higashiosaka, Osaka, Japan Kyoto Univ, Kyoto, Japan Med Univ Warsaw, Warsaw, Poland Minist Hlth, Rome, Italy Univ Catania, Catania, Italy CIBER Epidemiol & Salud Publ, Barcelona, Spain Univ KwaZulu Natal, Durban, South Africa Geneva Univ Hosp, Geneva, Switzerland Australian Bur Stat, Canberra, ACT, Australia Agcy Prevent & Social Med, Innsbruck, Austria Wageningen Univ, Wageningen, Netherlands Noncommunicable Dis Res Ctr, Shiraz, Iran Univ Insubria, Varese, Italy Lund Univ, Lund, Sweden Minist Hlth, Ankara, Turkey Minist Hlth, Jerusalem, Israel McGill Univ, Montreal, PQ, Canada Andes Clin Cardiometab Studies, Timotes, Venezuela Univ Politecn Madrid, Madrid, Spain Univ Lille 2, Lille, France Minist Hlth, Lisbon, Portugal Inst Clin & Expt Med, Prague, Czech Republic Childrens Mem Hlth Inst, Warsaw, Poland Alexander Technol Educ Inst, Sindos, Greece Dalhousie Univ, Halifax, NS, Canada Jagiellonian Univ, Med Coll, Krakow, Poland Univ Southern Denmark, Odense, Denmark Azienda Osped Univ Policlin Vittorio Emanuele, Catania, Italy Univ Novi Sad, Novi Sad, Serbia Natl Ctr Cardiovasc Dis, Beijing, Peoples R China Univ Ferrara, Ferrara, Italy Singapore Eye Res Inst, Singapore, Singapore Iceland Heart Assoc, Kopavogur, Iceland Univ Icesi, Cali, Colombia Univ Estadual Montes Claros, Montes Claros, Brazil Kings Coll London, London, England Int Agcy Res Canc, Lyon, France Capital Med Univ, Beijing, Peoples R China Healis Sekhsaria Inst Publ Hlth, Navi Mumbai, India Eternal Heart Care Ctr Res Inst, Jaipur, Rajasthan, India Univ Ibadan, Ibadan, Nigeria Childrens Memorial Hlth Inst, Warsaw, Poland Inst Clin Effectiveness & Hlth Policy, Buenos Aires, DF, Argentina Res & Educ Inst Child Hlth, Nicosia, Cyprus Minist Hlth, Seri Begawan, Brunei Danish Canc Soc, Res Ctr, Copenhagen, Denmark Univ West Indies, Bridgetown, Barbados Alexander Technol Educ Inst Thessaloniki, Sindos, Greece Kyushu Univ, Fukuoka, Japan Tulane Univ, New Orleans, LA 70118 USA Univ Pecs, Pecs, Hungary Univ Coll Dublin, Dublin, Ireland Univ Amsterdam, Acad Med Ctr, Amsterdam, Netherlands Natl Inst Publ Hlth, Cuernavaca, Morelos, Mexico Oulu Univ Hosp, SF-90100 Oulu, Finland Univ Autonoma Bucaramanga, Bucaramanga, Colombia Swiss Fed Inst Technol, Zurich, Switzerland Chron Diseases Res Ctr, Tehran, Iran Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China Chinese Univ Hong Kong, Hong Kong, Hong Kong, Peoples R China Univ Western Australia, Perth, WA, Australia Kingston Gen Hosp, Kingston, ON, Canada Heart Inst, Sao Paulo, Brazil Fdn Oftalmol Santander, Floridablanca, Colombia Univ Oran 1, Oran, Algeria Minist Hlth, Naypyitaw, Myanmar Vrije Univ Amsterdam, Med Ctr, Amsterdam, Netherlands Vrije Univ Amsterdam, Amsterdam, Netherlands Amer Univ Beirut, Beirut, Lebanon IRCCS Ist Neurol Mediterraneo Neuromed, Pozzilli, Italy Cardiol Mercato S Severino, Mercato San Severino, Italy Cairo Univ, Giza, Egypt Natl Inst Hlth & Nutr, Tokyo, Japan UHC Zagreb, Zagreb, Croatia Niigata Univ, Niigata, Japan Hadassah Univ, Med Ctr, Jerusalem, Israel Jordan Univ Sci & Technol, Irbid, Jordan Norwegian Univ Sci & Technol, Trondheim, Norway Sports Univ Tirana, Tirana, Albania Univ Zagreb, Sch Med, Zagreb, Croatia Heart Fdn, 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Algeria Minist Salud Publ, Havana, Cuba Sahlgrens Acad, Gothenburg, Sweden Endocrinol & Met Res Ctr, Arak, Iran Indicium Res, Manila, Philippines Food & Agr Org, Rome, Italy Natl Univ Singapore, Singapore, Singapore Tampere Univ Hosp, Tampere, Finland Univ Cape Town, Cape Town, South Africa West Virginia Univ, Morgantown, WV USA Fundacao Oswaldo Cruz, Rene Rachou Res Inst, Belo Horizonte, MG, Brazil Natl Taiwan Univ, Taipei, Taiwan Univ Chinese Acad Sci, Beijing, Peoples R China Uppsala Univ, Uppsala, Sweden Capital Med Univ, Beijing An Zhen Hosp, Beijing, Peoples R China Natl Inst Hlth Dev, Tallinn, Estonia Univ Med Greifswald, Greifswald, Germany Consejeria Sanidad Junta Castilla & Leon, Valladolid, Spain Univ Fed Ouro Pret, Ouro Preto, Brazil Jikei Univ, Sch Med, Tokyo, Japan CNR, Rome, Italy Baker Heart & Diabet Inst, Melbourne, Vic, Australia Agr Univ Athens, Athens, Greece Univ Putra Malaysia, Seri Kembangan, Malaysia Inst Rech Dev, Marseille, France Hosp Israelita Albert Einstein, Sao Paulo, Brazil Shiraz Univ Med Sci, Shiraz, Iran Inst Internal & Prevent Med, Novosibirsk, Russia Harokopio Univ, Kallithea, Greece Univ Otago, Dunedin, New Zealand Univ Padua, Padua, Italy Technol Educ Inst Crete, Iraklion, Greece Loughborough Univ Technol, Loughborough, Leics, England Univ Fed Santa Catarina, Florianopolis, SC, Brazil Lausanne Univ Hosp, Lausanne, Switzerland Inst Hosp Mard Invest Med, Barcelona, Spain Mary Immaculate Coll, Limerick, Ireland Emory Univ, Atlanta, GA 30322 USA Hungarian Soc Sports Med, Budapest, Hungary Sherikashmir Inst Med Sci, Srinagar, Jammu & Kashmir, India UiT Arctic Univ Norway, Tromso, Norway Cape Peninsula Univ Technol, Cape Town, South Africa Univ Rzeszow, Rzeszow, Poland Univ Yaounde I, Yaounde, Cameroon Brown Univ, Providence, RI 02912 USA Univ Edinburgh, Edinburgh, Midlothian, Scotland Stat Canada, Ottawa, ON, Canada Int Med Univ, Kuala Lumpur, Malaysia INSERM, Villejuif, France Helmholtz Zentrum Munchen, Oberschleissheim, Germany Robert Koch Inst, Berlin, Germany Lusofona Univ, Lisbon, Portugal Democritus Univ Greece, Komotini, Greece Grigore T Popa Univ Med & Pharm, Iasi, Romania Univ Firenze, Florence, Italy Hypertens Res Ctr, Esfahan, Iran Mulago Hosp, Kampala, Uganda Univ Limpopo, Polokwane, South Africa Seoul Natl Univ, Childrens Hosp, Seoul, South Korea Univ Fed Rio Grande do Sul, Porto Alegre, RS, Brazil Univ Med Sci, Havana, Cuba Univ Zaragoza, Zaragoza, Spain R CSI Dublin, Dublin, Ireland Int Inst Mol & Cell Biol, Warsaw, Poland Ain Shams University, Cairo, Egypt Ahvaz Jundishapur Univ Med Sci, Ahwaz, Iran Gorgas Memorial Inst Publ Hlth, Panama City, Panama Dept Publ Hlth, Nay Pyi Taw, Myanmar Univ Brescia, Brescia, Italy Helmholtz Zentrum Munchen, Neuherberg, Germany Univ Eastern Finland, Kuopio, Finland Mary Immaculate Coll, Tours, France Bushehr Univ Med Sci, Bushehr, Iran Ulm Univ, Ulm, Germany Inst Publ Hlth, Kuala Lumpur, Malaysia Kobe Univ, Kobe, Hyogo, Japan Banska Bystrica Reg Author Publ Hlth, Banska Bystrica, Slovakia Suraj Eye Inst, Nagpur, Maharashtra, India Helen Keller Int, Yaounde, Cameroon Karolinska Inst, Solna, Sweden Natl Inst Hyg & Epidemiol, Hanoi, Vietnam Univ Pharm & Med Ho Chi Minh City, Ho Chi Minh City, Vietnam Hanoi Med Univ, Hanoi, Vietnam Miami Vet Affairs Healthcare Syst, Miami, FL USA Heartfile, Islamabad, Pakistan Natl Canc Ctr, Tokyo, Japan Eastern Mediterranean Publ Hlth Network, Amman, Jordan State Univ Med & Pharm, Kishinev, Moldova Tachikawa Gen Hosp, Tachikawa, Tokyo, Japan Acad Hosp Paramaribo, Paramaribo, Surinam Univ Vale Rio dos Sinos, Sao Leopoldo, Brazil Natl Food & Nutr Inst, Warsaw, Poland Minist Hlth, Bandar Seri Begawan, Brunei Univ Fed Santa Catarin, Florianopolis, SC, Brazil Univ Madeira, Funchal, Portugal Univ Puerto Rico, San Juan, PR USA MRC Lifecourse Epidemiol Unit, Southampton, Hants, England Aarhus Univ, Aarhus, Denmark Kwame Nkrumah Univ Sci & Technol, Kumasi, Ghana Inst Social & Prevent, Lausanne, Switzerland Canc Prevent & Res Inst, Florence, Italy Univ Wisconsin Madison, Madison, WI USA IRCCS Casa Sollievo Sofferenz, San Giovanni Rotondo, Italy Zayed Univ, Dubai, U Arab Emirates Catholic Univ Daegu, Gyongsan, South Korea Tg Mures Univ Med & Pharm, Targu Mures, Romania Jivandeep Hosp, Surat, India South African Med Res Council, Tygerberg, South Africa Univ Med Ctr Utrecht, Utrecht, Netherlands Fundacao Oswaldo Cruz, Rene Rachou Res Inst, Rio De Janeiro, Brazil Spanish Agcy Consumer Affairs Social Serv & Nutr, Madrid, Spain Univ Puerto Rico, Med Sci Campus, San Juan, PR USA Minist Hlth & Med Educ, Tehran, Iran Vietnam Natl Heart Inst, Hanoi, Vietnam Leibniz Inst Prevent Res & Epidemiol BIPS, Bremen, Germany Univ Sarajevo, Sarajevo, Bosnia & Herceg Cardiovasc Prevent Ctr Udine, Udine, Italy Univ Hosp Pisa, Pisa, Italy Minist Hlth & Med Serv, Honiara, Solomon Islands Publ Hlth Agcy Catalonia, Barcelona, Spain Univ Kebangsaan Malaysia, Kuala Lumpur, Malaysia Univ Montenegro, Podgorica, Montenegro Inst Hosp Mar Invest Med, Barcelona, Spain Agcy Prevent and Social Med, Innsbruck, Austria Digest Oncol Res Ctr, Tehran, Iran Digest Dis Res Inst, Tehran, Iran CHU Vaudois, Lausanne, Switzerland Ctr Dis & Prevent Control, Riga, Latvia Al Quds Univ, Jerusalem, Israel Alborz Univ Med Sci, Karaj, Iran Minist Hlth, Hanoi, Vietnam BRAC, Dhaka, Bangladesh Inst Epidemiol Dis Control & Res, Dhaka, Bangladesh Univ Turku, Turku, Finland India Diabet Res Fdn, Madras, Tamil Nadu, India Univ New South Wales, Sydney, NSW, Australia Inst Univ Invest Atencio Primaria Jordi Gol, Barcelona, Spain Univ Malaya, Kuala Lumpur, Malaysia Univ Valencia, Valencia, Spain Univ Philippines, Quezon City, Philippines Nutr Res Fdn, Barcelona, Spain Minas Gerais State Secretariat Hlth, Belo Horizonte, MG, Brazil Hlth Ctr San Agustin, San AgustIn, Spain PharmAccess Fdn, Amsterdam, Netherlands Natl Inst Hlth Doutor Ricardo Jorge, Lisbon, Portugal Publ Hlth Agcy Canada, Ottawa, ON, Canada Canarian Hlth Serv, Barcelona, Spain Univ Ind Santander, Bucaramanga, Colombia Inst Nacl Salud Publ, Mexico City, DF, Mexico CIBEROBN, Madrid, Spain Gothenburg Univ, Gothenburg, Sweden Fiji Natl Univ, Suva, Fiji CNR, Inst Food Sci, Rome, Italy Sitaram Bhartia Inst Sci & Res, New Delhi, India Univ Tunis El Mana, Tunis, Tunisia Natl Inst Publ Hlth, Mexico City, DF, Mexico Univ Helsinki, Helsinki, Finland Natl Inst Hlth Peru, Lima, Peru Minist Hlth, South Jakarta, Indonesia Catalan Dept Hlth, Barcelona, Spain Publ Hlth Subdelegate Off, Barcelona, Spain Univ Lisbon, Lisbon, Portugal Prevent Med & Publ Hlth, Lisbon, Portugal Univ Sao Paulo, Clin Hosp, Sao Paulo, Brazil South Karelia Social & Hlth Care Dist, Lappeenranta, Finland Isfahan Cardiovasc Res Ctr, Esfahan, Iran Hosp Italiano Buenos Aires, Buenos Aires, DF, Argentina Rigshosp, Copenhagen, Denmark Minist Hlth, Naypyidaw, Myanmar Lagos State Univ, Coll Med, Lagos, Nigeria Univ Las Palmas Gran Canaria, Las Palmas Gran Canaria, Spain Baker Heart and Diabet Inst, Melbourne, Vic, Australia Univ Tokyo, Tokyo, Japan Samsung Med Ctr, Seoul, South Korea Finnish Inst Occupat Hlth, Helsinki, Finland St Vincents Hosp, Melbourne, Vic, Australia Acad Med Ctr Amsterdam, Amsterdam, Netherlands Hlth Polytech Jakarta II Inst, Jakarta, Indonesia Univ Bari, Bari, Italy Inst Reg Sante Publ, Cotonou, Benin Univ Bordeaux, Bordeaux, France Inst Publ Hlth Republ Macedonia, Skopje, Macedonia Univ Leuven, Leuven, Belgium Lamprecht & Stamm Sozialforsch & Beratung AG, Zurich, Switzerland INSERM, Paris, France Univ Bonn, Bonn, Germany Sotiria Hosp, Athens, Greece Natl Inst Publ Hlth, Natl Inst Hyg, Warsaw, Poland Swansea Univ, Swansea, W Glam, Wales Fu Jen Catholic Univ, New Taipei, Taiwan Minist Hlth, Amman, Jordan Natl Inst Hlth, Lima, Peru UNICEF, Yaounde, Cameroon Danish Canc Soc Res Ctr, Copenhagen, Denmark Hlth Serv Murcia, Murcia, Spain Res & Educ Inst, Nicosia, Cyprus IB SALUT Area Salut Menorca, Palma de Mallorca, Spain Univ Bologna, Bologna, Italy Hellen Hlth Fdn, Athens, Greece Univ Pharm & Med Ho Chi Min City, Ho Chi Minh, Vietnam Governm Med Coll, Secunderabad, India Sefako Makgatho Hlth Sci Univ, Kangnung, South Korea Addis Ababa Univ, Addis Ababa, Ethiopia Dasman Diabet Inst, Kuwait, Kuwait Minist Hlth, Thorndon, New Zealand Hellen Med Associat Obes, Athens, Greece Univ Ctr Occidental Lisandro Alvarado, Barquisimeto, Venezuela Meharry Med Coll, Nashville, TN USA Dokuz Eylul Univ, Izmir, Turkey Univ Tampere, Tays Eye Ctr, Tampere, Finland Polytech Inst Porto, Oporto, Portugal Univ Utrecht, Utrecht, Netherlands Amsterdam Publ Hlth Res Inst, Amsterdam, Netherlands Univ Fed Minas Gerais, Belo Horizonte, MG, Brazil Natl Inst Publ Hlth & Environm, Bilthoven, Netherlands Fed Univ Pelota, Pelotas, Brazil Italian Natl Res Council, Rome, Italy Univ Miguel Hernandez, Elche, Spain Minist Hlth, Victoria, Seychelles North Karelian Ctr Publ Hlth, Joensuu, Finland ISGlobal Ctr Res Environm Epidemiol, Barcelona, Spain Univ Witwatersrand, Johannesburg, South Africa Med Univ Vienna, Vienna, Austria Univ Coll Cork, Cork, Ireland Inst Med Res, Kuala Lumpur, Malaysia Xinjiang Med Univ, Urumqi, Peoples R China St Georges Univ London, London, England Univ Indonesia, Depok, Indonesia Natl Inst Hyg, Warsaw, Poland Caja Costarricense Seguro Social, Atenas, Costa Rica Univ Kebangsaan Malaysia, Bangi Selangor, Malaysia Univ New South Wales, Kensington, NSW, Australia Univ Mancheste, Manchester, Lancs, England Shandong Univ Tradit Chinese Med, Jinan, Shandong, Peoples R China Kailuan Gen Hosp, Tangshan, Peoples R China Minist Agr, Inst Food & Dev, Beijing, Peoples R China Fudan Univ, Childrens Hosp, Shanghai, Peoples R China Chinese Ctr Dis Control & Prevent, Beijing, Peoples R China Univ Cyprus, Nicosia, Cyprus Univ Teknol MARA, Shah Alam, Malaysia Capital Med Univ Beijing, An Zhen Hosp, Beijing, Peoples R China West Kazakhstan State Med Univ, Aktobe, Kazakhstan Inner Mongolia Med Univ, Hohhot, Peoples R China Gorgas Mem Inst Publ Hlth, Panama City, Panama Univ Estadual Paulista, Sao Paulo, Brazil
Published: 2017

6. Worldwide trends in blood pressure from 1975 to 2015: a pooled analysis of 1479 population-based measurement studies with 19.1 million participants

Author: Zhou, B, Bentham, J, Di Cesare, M, Bixby, H, Danaei, G, Cowan, MJ, Paciorek, CJ, Singh, G, Hajifathalian, K, Bennett, JE, Taddei, C, Bilano, V, Carrillo-Larco, RM, Djalalinia, S, Khatibzadeh, S, Lugero, C, Peykari, N, Zhang, WZ, Lu, Y, Stevens, GA, Riley, LM, Bovet, P, Elliott, P, Gu, D, Ikeda, N, Jackson, RT, Joffres, M, Kengne, AP, Laatikainen, T, Lam, TH, Laxmaiah, A, Liu, J, Miranda, JJ, Mondo, CK, Neuhauser, HK, Sundstrom, J, Smeeth, L, Soric, M, Woodward, M, Ezzati, M, Abarca-Gomez, L, Abdeen, ZA, Rahim, HA, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, R, Aekplakorn, W, Afsana, K, Aguilar-Salinas, CA, Agyemang, C, Ahmadvand, A, Ahrens, W, Al Raddadi, R, Al Woyatan, R, Ali, MM, Alkerwi, A, Aly, E, Amouyel, P, Amuzu, A, Andersen, LB, Anderssen, SA, Angquist, L, Anjana, RM, Ansong, D, Aounallah-Skhiri, H, Araujo, J, Ariansen, I, Aris, T, Arlappa, N, Aryal, K, Arveiler, D, Assah, FK, Assuncao, MCF, Avdicova, M, Azevedo, A, Azizi, F, Babu, BV, Bahijri, S, Balakrishna, N, Bandosz, P, Banegas, JR, Barbagallo, CM, Barcelo, A, Barkat, A, Barros, AJD, Barros, MV, Bata, I, Batieha, AM, Baur, LA, Beaglehole, R, Ben Romdhane, H, Benet, M, Benson, LS, Bernabe-Ortiz, A, Bernotiene, G, Bettiol, H, Bhagyalaxmi, A, Bharadwaj, S, Bhargava, SK, Bi, Y, Bikbov, M, Bjerregaard, P, Bjertness, E, Bjokelund, C, Blokstra, A, Bo, S, Bobak, M, Boeing, H, Boggia, JG, Boissonnet, CP, Bongard, V, Braeckman, L, Brajkovich, I, Branca, F, Breckenkamp, J, Brenner, H, Brewster, LM, Bruno, G, Bueno-de-Mesquita, HBA, Bugge, A, Burns, C, Bursztyn, M, de Leon, AC, Cameron, C, Can, G, Candido, APC, Capuano, V, Cardoso, VC, Carlsson, AC, Carvalho, MJ, Casanueva, FF, Casas, J-P, Caserta, CA, Chamukuttan, S, Chan, AW, Chan, Q, Chaturvedi, HK, Chaturvedi, N, Chen, C-J, Chen, F, Chen, H, Chen, S, Chen, Z, Cheng, C-Y, Dekkaki, IC, Chetrit, A, Chiolero, A, Chiou, S-T, Chirita-Emandi, A, Cho, B, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Clays, E, Concin, H, Cooper, C, Cooper, R, Coppinger, TC, Costanzo, S, Cottel, D, Cowell, C, Craig, CL, Crujeiras, AB, Cruz, JJ, D'Arrigo, G, d'Orsi, E, Dallongeville, J, Damasceno, A, Dankner, R, Dantoft, TM, Dauchet, L, De Backer, G, de Gaetano, G, De Henauw, S, De Smedt, D, Deepa, M, Dehghan, A, Delisle, H, Deschamps, V, Dhana, K, Di Castelnuovo, AF, Dias-da-Costa, JS, Diaz, A, Dickerson, TT, Do, HTP, Dobson, AJ, Donfrancesco, C, Donoso, SP, Doering, A, Doua, K, Drygas, W, Dulskiene, V, Dzakula, A, Dzerve, V, Dziankowska-Zaborszczyk, E, Eggertsen, R, Ekelund, U, El Ati, J, Ellert, U, Elosua, R, Erasmus, RT, Erem, C, Eriksen, L, Escobedo-de la Pena, J, Evans, A, Faeh, D, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernandez-Berges, D, Ferrante, D, Ferrari, M, Ferreccio, C, Ferrieres, J, Finn, JD, Fischer, K, Foeger, B, Foo, LH, Forslund, A-S, Forsner, M, Fortmann, SP, Fouad, HM, Francis, DK, Franco, MDC, Franco, OH, Frontera, G, Fuchs, FD, Fuchs, SC, Fujita, Y, Furusawa, T, Gaciong, Z, Gareta, D, Garnett, SP, Gaspoz, J-M, Gasull, M, Gates, L, Gavrila, D, Geleijnse, JM, Ghasemian, A, Ghimire, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Goldsmith, RA, Goncalves, H, Gonzalez Gross, M, Gonzalez Rivas, JP, Gottrand, F, Graff-Iversen, S, Grafnetter, D, Grajda, A, Gregor, RD, Grodzicki, T, Grontved, A, Gruden, G, Grujic, V, Guan, OP, Gudnason, V, Guerrero, R, Guessous, I, Guimaraes, AL, Gulliford, MC, Gunnlaugsdottir, J, Gunter, M, Gupta, PC, Gureje, O, Gurzkowska, B, Gutierrez, L, Gutzwiller, F, Hadaegh, F, Halkjaer, J, Hambleton, IR, Hardy, R, Harikumar, R, Hata, J, Hayes, AJ, He, J, Hendriks, ME, Henriques, A, Hernandez Cadena, L, Herqutanto, Herrala, S, Heshmat, R, Hihtaniemi, IT, Ho, SY, Ho, SC, Hobbs, M, Hofman, A, Dinc, GH, Hormiga, CM, Horta, BL, Houti, L, Howitt, C, Htay, TT, Htet, AS, Hu, Y, Maria Huerta, J, Husseini, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikram, MA, Irazola, VE, Islam, M, Ivkovic, V, Iwasaki, M, Jacobs, JM, Jafar, T, Jamrozik, K, Janszky, I, Jasienska, G, Jelakovic, B, Jiang, CQ, Johansson, M, Jonas, JB, Jorgensen, T, Joshi, P, Juolevi, A, Jurak, G, Juresa, V, Kaaks, R, Kafatos, A, Kalter-Leibovici, O, Kamaruddin, NA, Kasaeian, A, Katz, J, Kauhanen, J, Kaur, P, Kavousi, M, Kazakbaeva, G, Keil, U, Boker, LK, Keinanen-Kiukaanniemi, S, Kelishadi, R, Kemper, HCG, Kersting, M, Key, T, Khader, YS, Khalili, D, Khang, Y-H, Khaw, K-T, Kiechl, S, Killewo, J, Kim, J, Klumbiene, J, Kolle, E, Kolsteren, P, Korrovits, P, Koskinen, S, Kouda, K, Koziel, S, Kristensen, PL, Krokstad, S, Kromhout, D, Kruger, HS, Kubinova, R, Kuciene, R, Kuh, D, Kujala, UM, Kula, K, Kulaga, Z, Kumar, RK, Kurjata, P, Kusuma, YS, Kuulasmaa, K, Kyobutungi, C, Lachat, C, Landrove, O, Lanska, V, Lappas, G, Larijani, B, Laugsand, LE, Bao, KLN, Le, TD, Leclercq, C, Lee, J, Lehtimaki, T, Lekhraj, R, Leon-Munoz, LM, Levitt, NS, Li, Y, Lilly, CL, Lim, W-Y, Fernanda Lima-Costa, M, Lin, H-H, Lin, X, Linneberg, A, Lissner, L, Litwin, M, Lorbeer, R, Lotufo, PA, Eugenio 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Vineis, P, Vioque, J, Virtanen, JK, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Vrdoljak, A, Vrijheid, M, Wade, AN, Wagner, A, Walton, J, Mohamud, WNW, Wang, M-D, Wang, Q, Wang, YX, Wannamethee, SG, Wareham, N, Wederkopp, N, Weerasekera, D, Whincup, PH, Widhalm, K, Widyahening, IS, Wiecek, A, Wijga, AH, Wilks, RJ, Willeit, P, Williams, EA, Wilsgaard, T, Wojtyniak, B, Wong, TY, Wong-McClure, RA, Woo, J, Wu, AG, Wu, FC, Wu, SL, Xu, H, Yan, W, Yang, X, Ye, X, Yiallouros, PK, Yoshihara, A, Younger-Coleman, NO, Yusoff, AF, Zambon, S, Zdrojewski, T, Zeng, Y, Zhao, D, Zhao, W, Zheng, Y, Zhu, D, Zimmermann, E, Zuniga Cisneros, J, Collaboration, NCDRF, Internal Medicine, Epidemiology, Public Health, Clinical Genetics, Cardiology, APH - Global Health, APH - Personalized Medicine, Public and occupational health, ACS - Amsterdam Cardiovascular Sciences, Vascular Medicine, Other departments, APH - Quality of Care, Global Health, Infectious diseases, APH - Aging & Later Life, APH - Health Behaviors & Chronic Diseases, APH - Methodology, ACS - Diabetes & metabolism, ACS - Atherosclerosis & ischemic syndromes, ACS - Heart failure & arrhythmias, Zhou, Bin, Bentham, Jame, Di Cesare, Mariachiara, Bixby, Honor, Danaei, Goodarz, Cowan, Melanie J, Paciorek, Christopher J, Singh, Gitanjali, Hajifathalian, Kaveh, Bennett, James E., Taddei, Cristina, Bilano, Ver, Carrillo-Larco, Rodrigo M, Djalalinia, Shirin, Khatibzadeh, Shahab, Lugero, Charle, Peykari, Niloofar, Zhang, Wan Zhu, Lu, Yuan, Stevens, Gretchen A, Riley, Leanne M, Bovet, Pascal, Elliott, Paul, Gu, Dongfeng, Ikeda, Nayu, Jackson, Rod T., Joffres, Michel, Kengne, Andre Pascal, Laatikainen, Tiina, Lam, Tai Hing, Laxmaiah, Avula, Liu, Jing, Miranda, J Jaime, Mondo, Charles K, Neuhauser, Hannelore K., Sundström, Johan, Smeeth, Liam, Sorić, Maroje, Woodward, Mark, Ezzati, Majid, Abarca-Gómez, Leandra, Abdeen, Ziad A, Rahim, Hanan Abdul, Abu-Rmeileh, Niveen M, Acosta-Cazares, Benjamin, Adams, Robert, Aekplakorn, Wichai, Afsana, Kaosar, Aguilar-Salinas, Carlos A, Agyemang, Charle, Ahmadvand, Alireza, Ahrens, Wolfgang, Al Raddadi, Rajaa, Al Woyatan, Rihab, Ali, Mohamed M, Alkerwi, Ala'a, Aly, Eman, Amouyel, Philippe, Amuzu, Antoinette, Andersen, Lars Bo, Anderssen, Sigmund A, Ängquist, Lar, Anjana, Ranjit Mohan, Ansong, Daniel, Aounallah-Skhiri, Hajer, Araújo, Joana, Ariansen, Inger, Aris, Tahir, Arlappa, Nimmathota, Aryal, Krishna, Arveiler, Dominique, Assah, Felix K, Assunção, Maria Cecília F, Avdicová, Mária, Azevedo, Ana, Azizi, Fereidoun, Babu, Bontha V, Bahijri, Suhad, Balakrishna, Nagalla, Bandosz, Piotr, Banegas, José R., Barbagallo, Carlo M, Barceló, Alberto, Barkat, Amina, Barros, Aluisio J.D., Barros, Mauro V., Bata, Iqbal, Batieha, Anwar M, Baur, Louise A, Beaglehole, Robert, Romdhane, Habiba Ben, Benet, Mikhail, Benson, Lowell S, Bernabe-Ortiz, Antonio, Bernotiene, Gailute, Bettiol, Heloisa, Bhagyalaxmi, Aroor, Bharadwaj, Sumit, Bhargava, Santosh K., Bi, Yufang, Bikbov, Mukharram, Bjerregaard, Peter, Bjertness, Espen, Björkelund, Cecilia, Blokstra, Anneke, Bo, Simona, Bobak, Martin, Boeing, Heiner, Boggia, Jose G., Boissonnet, Carlos P, Bongard, Vanina, Braeckman, Lutgart, Brajkovich, Imperia, Branca, Francesco, Breckenkamp, Juergen, Brenner, Hermann, Brewster, Lizzy M., Bruno, Graziella, Bueno-de-Mesquita, H B(as), Bugge, Anna, Burns, Con, Bursztyn, Michael, de León, Antonio Cabrera, Cacciottolo, Joseph, Cameron, Christine, Can, Günay, Cândido, Ana Paula C., Capuano, Vincenzo, Cardoso, Viviane C, Carlsson, Axel C., Carvalho, Maria J., Casanueva, Felipe F., Casas, Juan-Pablo, Caserta, Carmelo A., Chamukuttan, Snehalatha, Chan, Angelique W., Chan, Queenie, Chaturvedi, Himanshu K, Chaturvedi, Nishi, Chen, Chien-Jen, Chen, Fangfang, Chen, Huashuai, Chen, Shuohua, Chen, Zhengming, Cheng, Ching-Yu, Dekkaki, Imane Cherkaoui, Chetrit, Angela, Chiolero, Arnaud, Chiou, Shu-Ti, Chirita-Emandi, Adela, Cho, Belong, Cho, Yumi, Chudek, Jerzy, Cifkova, Renata, Claessens, 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Stela, McLean, Rachael M, McNulty, Breige A, MdKhir, Amir Sharifuddin, Mediene-Benchekor, Sounnia, Medzioniene, Jurate, Meirhaeghe, Aline, Meisinger, Christa, Menezes, Ana Maria B, Menon, Geetha R, Meshram, Indrapal I, Metspalu, Andre, Mi, Jie, Mikkel, Kairit, Miller, Jody C, Miquel, Juan Francisco, Mišigoj-Durakovic, Marjeta, Mohamed, Mostafa K, Mohammad, Kazem, Mohammadifard, Noushin, Mohan, Viswanathan, Mohd Yusoff, Muhammad Fadhli, Møller, Niels C, Molnár, Déne, Momenan, Amirabba, Monyeki, Kotsedi Daniel K, Moreira, Leila B, Morejon, Alain, Moreno, Luis A, Morgan, Karen, Moschonis, George, Mossakowska, Malgorzata, Mota, Jorge, Mostafa, Aya, Motlagh, Mohammad Esmaeel, Motta, Jorge, Muiesan, Maria L, Müller-Nurasyid, Martina, Murphy, Neil, Mursu, Jaakko, Musil, Vera, Nagel, Gabriele, Naidu, Balkish M, Nakamura, Harunobu, Námešná, Jana, Nang, Ei Ei K, Nangia, Vinay B, Narake, Sameer, Navarrete-Muñoz, Eva Maria, Ndiaye, Ndeye Coumba, Neal, William A, Nenko, Ilona, Nervi, Flavio, 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Maria, Polašek, Ozren, Porta, Miquel, Portegies, Marileen L.P., Pourshams, Akram, Pradeepa, Rajendra, Prashant, Mathur, Price, Jacqueline F, Puiu, Maria, Punab, Margu, Qasrawi, Radwan F, Qorbani, Mostafa, Radic, Ivana, Radisauskas, Ricarda, Rahman, Mahfuzar, Raitakari, Olli, Raj, Manu, Rao, Sudha Ramachandra, Ramachandran, Ambady, Ramos, Elisabete, Rampal, Sanjay, Rangel Reina, Daniel A, Rasmussen, Finn, Redon, Josep, Reganit, Paul Ferdinand M, Ribeiro, Robespierre, Riboli, Elio, Rigo, Fernando, Rinke de Wit, Tobias F, Ritti-Dias, Raphael M, Robinson, Sian M, Robitaille, Cynthia, Rodríguez-Artalejo, Fernando, del Cristo Rodriguez-Perez, María, Rodríguez-Villamizar, Laura A, Rojas-Martinez, Rosalba, Rosengren, Annika, Rubinstein, Adolfo, Rui, Ornela, Ruiz-Betancourt, Blanca Sandra, Russo Horimoto, Andrea R V, Rutkowski, Marcin, Sabanayagam, Charumathi, Sachdev, Harshpal S, Saidi, Olfa, Sakarya, Sibel, Salanave, Benoit, Martinez, Eduardo Salazar, Salmerón, Diego, Salomaa, Veikko, 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Valkengoed, Irene G.M., Vanderschueren, Dirk, Vanuzzo, Diego, Vatten, Lar, Vega, Toma, Velasquez-Melendez, Gustavo, Veronesi, Giovanni, Verschuren, W M Monique, Verstraeten, Roosmarijn, Victora, Cesar G, Viet, Lucie, Viikari-Juntura, Eira, Vineis, Paolo, Vioque, Jesu, Virtanen, Jyrki K, Visvikis-Siest, Sophie, Viswanathan, Bharathi, Vollenweider, Peter, Voutilainen, Sari, Vrdoljak, Ana, Vrijheid, Martine, Wade, Alisha N, Wagner, Aline, Walton, Janette, Wan Mohamud, Wan Nazaimoon, Wang, Ming-Dong, Wang, Qian, Wang, Ya Xing, Wannamethee, S Goya, Wareham, Nichola, Wederkopp, Niel, Weerasekera, Deepa, Whincup, Peter H, Widhalm, Kurt, Widyahening, Indah S, Wijga, Alet H, Wiecek, Andrzej, Wilks, Rainford J, Willeit, Johann, Willeit, Peter, Williams, Emmanuel A, Wilsgaard, Tom, Wojtyniak, Bogdan, Wong, Tien Yin, Wong-McClure, Roy A, Woo, Jean, Wu, Aleksander Giwercman, Wu, Frederick C., Wu, Shou Ling, Xu, Haiquan, Yan, Weili, Yang, Xiaoguang, Ye, Xingwang, Yiallouros, Panayiotis K, Yoshihara, Akihiro, Younger-Coleman, Novie O, Yusoff, Ahmad F, Yusoff, Muhammad Fadhli M, Zambon, Sabina, Zdrojewski, Tomasz, Zeng, Yi, Zhao, Dong, Zhao, Wenhua, Zheng, Yingffeng, Zimmermann, Esther, Cisneros, Julio Zuñiga, Zhu, Dan, and Eggertsen, Robert
Subjects: presión sanguínea, hypertension, Settore MED/09 - Medicina Interna, united-states, humanos, Blood Pressure, systematic analysis, Global Health, Risk Factors, General & Internal Medicine, Prevalence, factores de riesgo, Humans, secular trends, cardiovascular risk-factors, Medicine (all), global burden, prevalencia, Bayes Theorem, gender-differences, purl.org/pe-repo/ocde/ford#3.02.00 [https], sodium-intake, health examination surveys, low-income, teorema de Bayes
Abstract: Background Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. Methods For this analysis, we pooled national, subnational, or community population-based studies that had measured blood pressure in adults aged 18 years and older. We used a Bayesian hierarchical model to estimate trends from 1975 to 2015 in mean systolic and mean diastolic blood pressure, and the prevalence of raised blood pressure for 200 countries. We calculated the contributions of changes in prevalence versus population growth and ageing to the increase in the number of adults with raised blood pressure. Findings We pooled 1479 studies that had measured the blood pressures of 19.1 million adults. Global age-standardised mean systolic blood pressure in 2015 was 127.0 mm Hg (95% credible interval 125.7-128.3) in men and 122.3 mm Hg (121.0-123.6) in women; age-standardised mean diastolic blood pressure was 78.7 mm Hg (77.9-79.5) for men and 76.7 mm Hg (75.9-77.6) for women. Global age-standardised prevalence of raised blood pressure was 24.1% (21.4-27.1) in men and 20.1% (17.8-22.5) in women in 2015. Mean systolic and mean diastolic blood pressure decreased substantially from 1975 to 2015 in high-income western and Asia Pacific countries, moving these countries from having some of the highest worldwide blood pressure in 1975 to the lowest in 2015. Mean blood pressure also decreased in women in central and eastern Europe, Latin America and the Caribbean, and, more recently, central Asia, Middle East, and north Africa, but the estimated trends in these super-regions had larger uncertainty than in high-income super-regions. By contrast, mean blood pressure might have increased in east and southeast Asia, south Asia, Oceania, and sub-Saharan Africa. In 2015, central and eastern Europe, sub-Saharan Africa, and south Asia had the highest blood pressure levels. Prevalence of raised blood pressure decreased in high-income and some middle-income countries; it remained unchanged elsewhere. The number of adults with raised blood pressure increased from 594 million in 1975 to 1.13 billion in 2015, with the increase largely in low-income and middle-income countries. The global increase in the number of adults with raised blood pressure is a net effect of increase due to population growth and ageing, and decrease due to declining age-specific prevalence. Interpretation During the past four decades, the highest worldwide blood pressure levels have shifted from high-income countries to low-income countries in south Asia and sub-Saharan Africa due to opposite trends, while blood pressure has been persistently high in central and eastern Europe. Funding Wellcome Trust., Wellcome Trust.
Published: 2017

7. Bioactive type A proanthocyanins from fungus Laurobasidium lauri

Author: Serina, J, additional, Carvalho, MJ, additional, Weinhold, T, additional, and Castilho, PC, additional
Published: 2016
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8. Trends in adult body-mass index in 200 countries from 1975 to 2014: a pooled analysis of 1698 population-based measurement studies with 19.2 million participants

Author: di Cesare, M, Bentham, J, Stevens, GA, Zhou, B, Danaei, G, Lu, Y (Yi), Bixby, H, Cowan, MJ, Riley, LM, Hajifathalian, K, Fortunato, L, Taddei, C, Bennett, JE, Ikeda, N, Khang, YH, Kyobutungi, C, Laxmaiah, A, Li, YP, Lin, HH, Miranda, JJ, Mostafa, A, Turley, ML, Paciorek, CJ, Gunter, M, Ezzati, M, Abdeen, ZA, Hamid, ZA, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, R, Aekplakorn, W, Aguilar-Salinas, CA, Ahmadvand, A, Ahrens, W, Ali, MM, Alkerwi, A, Alvarez-Pedrerol, M, Aly, E, Amouyel, P, Amuzu, A, Andersen, LB, Anderssen, SA, Andrade, DS, Anjana, RM, Aounallah-Skhiri, H, Ariansen, I, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicova, M, Azizi, F, Babu, BV, Balakrishna, N, Bandosz, P, Banegas, JR, Barbagallo, CM, Barcelo, A, Barkat, A, Barros, MV, Bata, I, Batieha, AM, Batista, RL, Baur, LA, Beaglehole, R, Ben Romdhane, H, Benet, M, Bernabe-Ortiz, A, Bernotiene, G, Bettiol, H, Bhagyalaxmi, A, Bharadwaj, S, Bhargava, SK, Bhatti, Z, Bhutta, ZA, Bi, HS, Bi, YF, Bjerregaard, P, Bjertness, E, Bjertness, MB, Bjorkelund, C, Blake, M, Blokstra, A, Bo, S, Bobak, M, Boddy, LM, Boehm, BO, Boeing, H, Boissonnet, CP, Bongard, V, Bovet, P, Braeckman, L, Bragt, MCE, Brajkovich, I, Branca, F, Breckenkamp, J, Brenner, H, Brewster, LM, Brian, GR, Bruno, G, Bueno-de-Mesquita, HB, Bugge, A, Burns, C, de Leon, AC, Cacciottolo, J, Cama, T, Cameron, C, Camolas, J, Can, G, Candido, APC, Capuano, V, Cardoso, VC, Carvalho, MJ, Casanueva, FF, Casas, JP, Caserta, CA, Castetbon, K, Chamukuttan, S, Chan, AW, Chan, Q, Chaturvedi, HK, Chaturvedi, N, Chen, CJ, Chen, FF, Chen, HS, Chen, SH, Chen, ZM, Cheng, CY (Ching-Yu), Chetrit, A, Chiolero, A, Chiou, ST, Chirita-Emandi, A, Cho, Y, Christensen, K, Chudek, J, Cifkova, R, Claessens, F, Clays, E, Concin, H, Cooper, C, Cooper, R, Coppinger, TC, Costanzo, S, Cottel, D, Cowell, C, Craig, CL, Crujeiras, AB, D'Arrigo, G, d'Orsi, E, Dallongeville, J, Damasceno, A, Damsgaard, CT, Danaei, GG, Dankner, R, Dauchet, L, de Backer, G, De Bacquer, D, de 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Mediene-Benchekor, S, Meirhaeghe, A, Meisinger, C, Mendes, LL, Menezes, AMB, Mensink, GBM, Meshram, II, Metspalu, A, Mi, J, Michaelsen, KF, Mikkel, K, Miller, JC, Miquel, JF, Misigoj-Durakovic, M, Mohamed, MK, Mohammad, K, Mohammadifard, N, Mohan, V, Yusoff, MFM, Molbo, D, Moller, NC, Molnar, D, Mondo, CK, Monterrubio, EA, Monyeki, KDK, Moreira, LB, Morejon, A, Moreno, LA, Morgan, K, Mortensen, EL, Moschonis, G, Mossakowska, M, Mota, J, Motlagh, ME, Motta, J, Mu, TT, Muiesan, ML, Muller-Nurasyid, M, Murphy, N, Mursu, J, Murtagh, EM, Musa, KI, Musil, V, Nagel, G, Nakamura, H, Namesna, J, Nang, EEK, Nangia, VB, Nankap, M, Narake, S, Navarrete-Munoz, EM, Nenko, I, Neovius, M, Nervi, F, Neuhauser, HK, Nguyen, ND, Nguyen, QN, Nieto-Martinez, RE, Ning, G, Ninomiya, T, Nishtar, S, Noale, M, Norat, T, Noto, D, Al Nsour, M, O'Reilly, D, Ochoa-Aviles, AM, Oh, K, Olayan, IH, Olinto, MTA, Oltarzewski, M, Omar, MA, Onat, A, Ordunez, P, Ortiz, AP, Osler, M, Osmond, C, Ostojic, SM, Otero, JA, Overvad, K, Paccaud, FM, Padez, C, Pajak, A, Palli, D, Palloni, A, Palmieri, L, Panda-Jonas, S, Panza, F, Parnell, WR, Parsaeian, M, Pednekar, MS, Peeters, PH, Peixoto, SV, Pereira, AC, Perez, CM (Cynthia), Peters, A, Peykari, N, Pham, ST, Pigeot, I, Pikhart, H, Pilav, A, Pilotto, L, Pistelli, F, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubio, P, Poh, BK, Porta, M, Portegies, Marileen, Poulimeneas, D, Pradeepa, R, Prashant, M, Price, JF, Puiu, M, Punab, M, Qasrawi, RF, Qorbani, M, Bao, TQ, Radic, I, Radisauskas, R, Rahman, M, Raitakari, O, Raj, M, Rao, SR, Ramachandran, A, Ramke, J, Ramos, R, Rampal, S, Rasmussen, F, Redon, J, Reganit, PFM, Ribeiro, R, Riboli, E, Rigo, F, de Wit, TFR, Ritti-Dias, RM, Rivera, JA, Robinson, SM, Robitaille, C, Rodriguez-Artalejo, F, Rodriguez-Perez, MD, Rodriguez-Villamizar, LA, Rojas-Martinez, R, Rojroongwasinkul, N, Romaguera, D, Ronkainen, K, Rosengren, A, Rouse, I, Rubinstein, A, Ruhli, FJ, Rui, O, Ruiz-Betancourt, BS, Horimoto, A, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Salanave, B, Martinez, ES, Salomaa, V, Salonen, JT, Salvetti, M, Sanchez-Abanto, J, Sandjaja, Sans, S, Santos, DA, Santos, O, dos Santos, RN, dos Santos, R, Sardinha, LB, Sarrafzadegan, N, Saum, KU, Savva, SC, Scazufca, M, Rosario, AS, Schargrodsky, H, Schienkiewitz, A, Schmidt, IM, Schneider, IJ, Schultsz, C, Schutte, A, Sein, AA, Senbanjo, IO, Sepanlou, SG, Shalnova, SA, Shaw, JE, Shibuya, K, Shin, YC, Shiri, R, Siantar, R, Sibai, AM, Silva, AM, Silva, DAS, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Smith, MC, Snijder, MB, So, HK, Sobngwi, E, Soderberg, S, Soekatri, MYE, Solfrizzi, V, Sonestedt, E, Sorensen, TIA, Soric, M, Jerome, CS, Soumare, A, Staessen, JA, Starc, G, Stathopoulou, MG, Staub, K, Stavreski, B, Steene-Johannessen, J, Stehle, P, Stein, AD, Stergiou, GS, Stessman, J, Stieber, J, Stockl, D, Stocks, T, Stokwiszewski, J, Stratton, G, Strufaldi, MW, Sun, CA, Sundstrom, J, Sung, YT, 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Widhalm, K, Widyahening, IS, Wiecek, A, Wilks, RJ, Willeit, J, Wojtyniak, B, Wong, JE, Wong, TY, Woo, J, Woodward, M, Wu, FC, Wu, JF, Wu, SL, Xu, HQ, Xu, L, Yamborisut, U, Yan, WL, Yang, XG, Yardim, N, Ye, XW, Yiallouros, PK, Yoshihara, A, You, QS, Younger-Coleman, NO, Yusoff, AF, Zainuddin, AA, Zambon, S, Zdrojewski, T, Zeng, Yaping, Zhao, D (Dan), Zhao, WH, Zheng, YF, Zhou, MG, Zhu, D, Zimmermann, E, Cisneros, JZ, di Cesare, M, Bentham, J, Stevens, GA, Zhou, B, Danaei, G, Lu, Y (Yi), Bixby, H, Cowan, MJ, Riley, LM, Hajifathalian, K, Fortunato, L, Taddei, C, Bennett, JE, Ikeda, N, Khang, YH, Kyobutungi, C, Laxmaiah, A, Li, YP, Lin, HH, Miranda, JJ, Mostafa, A, Turley, ML, Paciorek, CJ, Gunter, M, Ezzati, M, Abdeen, ZA, Hamid, ZA, Abu-Rmeileh, NM, Acosta-Cazares, B, Adams, R, Aekplakorn, W, Aguilar-Salinas, CA, Ahmadvand, A, Ahrens, W, Ali, MM, Alkerwi, A, Alvarez-Pedrerol, M, Aly, E, Amouyel, P, Amuzu, A, Andersen, LB, Anderssen, SA, Andrade, DS, Anjana, RM, Aounallah-Skhiri, H, Ariansen, I, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicova, M, Azizi, F, Babu, BV, Balakrishna, N, Bandosz, P, Banegas, JR, Barbagallo, CM, Barcelo, A, Barkat, A, Barros, MV, Bata, I, Batieha, AM, Batista, RL, Baur, LA, Beaglehole, R, Ben Romdhane, H, Benet, M, Bernabe-Ortiz, A, Bernotiene, G, Bettiol, H, Bhagyalaxmi, A, Bharadwaj, S, Bhargava, SK, Bhatti, Z, Bhutta, ZA, Bi, HS, Bi, YF, Bjerregaard, P, Bjertness, E, Bjertness, MB, Bjorkelund, C, Blake, M, Blokstra, A, Bo, S, Bobak, M, Boddy, LM, Boehm, BO, Boeing, H, Boissonnet, CP, Bongard, V, Bovet, P, Braeckman, L, Bragt, MCE, Brajkovich, I, Branca, F, Breckenkamp, J, Brenner, H, Brewster, LM, Brian, GR, Bruno, G, Bueno-de-Mesquita, HB, Bugge, A, Burns, C, de Leon, AC, Cacciottolo, J, Cama, T, Cameron, C, Camolas, J, Can, G, Candido, APC, Capuano, V, Cardoso, VC, Carvalho, MJ, Casanueva, FF, Casas, JP, Caserta, CA, Castetbon, K, Chamukuttan, S, Chan, AW, Chan, Q, Chaturvedi, HK, Chaturvedi, N, Chen, CJ, Chen, FF, Chen, HS, Chen, SH, Chen, ZM, Cheng, CY (Ching-Yu), Chetrit, A, Chiolero, A, Chiou, ST, Chirita-Emandi, A, Cho, Y, Christensen, K, Chudek, J, Cifkova, R, Claessens, F, Clays, E, Concin, H, Cooper, C, Cooper, R, Coppinger, TC, Costanzo, S, Cottel, D, Cowell, C, Craig, CL, Crujeiras, AB, D'Arrigo, G, d'Orsi, E, Dallongeville, J, Damasceno, A, Damsgaard, CT, Danaei, GG, Dankner, R, Dauchet, L, de Backer, G, De Bacquer, D, de Gaetano, G, de Henauw, S, De Smedt, D, Deepa, M, Deev, AD, Dehghan, Abbas, Delisle, H, Delpeuch, F, Dhana, K, di Castelnuovo, AF, Dias-Da-Costa, JS, Diaz, A, Djalalinia, S, Do, HTP, Dobson, AJ, Donfrancesco, C, Doring, A, Doua, K, Drygas, W, Egbagbe, EE, Eggertsen, R, Ekelund, U, El Ati, J, Elliott, P, Engle-Stone, R, Erasmus, RT, Erem, C, Eriksen, L, Escobedo-de la Pena, J, Evans, A, Faeh, D, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernandez-Berges, D, Ferrante, D, Ferrari, M, Ferreccio, C, Ferrieres, J, Finn, JD, Fischer, K, Flores, EM, Foger, B, Foo, LH, Forslund, AS, Fortmann, SP, Fouad, HM, Francis, DK, Franco, MD, Franco Duran, OH, Frontera, G, Fuchs, FD, Fuchs, SC, Fujita, Y, Furusawa, T, Gaciong, Z, Gafencu, M, Gareta, D, Garnett, SP, Gaspoz, JM, Gasull, M, Gates, L, Geleijnse, JM, Ghasemian, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Giwercman, A, Goldsmith, RA, Gross, MG, Rivas, JPG, Gorbea, MB, Gottrand, F, Iversen, SG, Grafnetter, D, Grajda, A, Grammatikopoulou, MG, Gregor, RD, Grodzicki, T, Grontved, A, Gruden, G, Grujic, V, Gu, DF, Guan, OP, Gudnason, V, Guerrero, R, Guessous, I, Guimaraes, AL, Gulliford, MC, Gunnlaugsdottir, J, Guo, XH, Guo, Y, Gupta, PC, Gureje, O, Gurzkowska, B, Gutierrez, L, Gutzwiller, F, Halkjaer, J, Hardy, R, Kumar, RH, Hayes, AJ, He, J, Hendriks, ME, Cadena, LH, Heshmat, R, Hihtaniemi, IT, Ho, SY, Ho, SC, Hobbs, M, Hofman, Bert, Hormiga, CM, Horta, BL, Houti, L, Htay, TT, Htet, AS, Htike, MMT, Hu, YH, Hussieni, AS, Huu, CN, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikram, Arfan, Irazola, VE, Islam, M, Iwasaki, M, Jackson, RT, Jacobs, JM, Jafar, T, Jamil, KM, Jamrozik, K, Jasienska, G, Jiang, CQ, Joffres, M, Johansson, M, Jonas, JB, Jorgensen, T, Joshi, P, Juolevi, A, Jurak, G, Juresa, V, Kaaks, R, Kafatos, A, Kalter-Leibovici, O, Kapantais, E, Kasaeian, A, Katz, J, Kaur, P, Kavousi, Maryam, Keil, U, Boker, LK, Kelishadi, R, Kemper, H, Kengne, AP, Kersting, M, Key, T, Khader, YS, Khalili, D, Khaw, KTH, Khouw, I, Kiechl, S, Killewo, J, Kim, J, Kiyohara, Y, Klimont, J, Kolle, E, Kolsteren, P, Korrovits, P, Koskinen, S, Kouda, K, Koziel, S, Kratzer, W, Krokstad, S, Kromhout, D, Kruger, HS, Kula, K, Kulaga, Z, Kumar, RK, Kusuma, YS, Kuulasmaa, K, Laamiri, FZ, Laatikainen, T, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Laugsand, L E, Bao, KLN, Le, TD, Leclercq, C, Lee, J, Lee, JJ, Lehtimaki, T, Lekhraj, R, Leon-Munoz, LM, Lim, WY, Lima-Costa, MF, Lin, X, Linneberg, A, Lissner, L, Litwin, M, Liu, J (Jingjing), Lorbeer, R, Lotufo, PA, Lozano, JE, Luksiene, D, Lundqvist, A, Lunet, N, Lytsy, P, Ma, GS, Machi, S, Maggi, S, Magliano, DJ, Makdisse, M, Malekzadeh, R, Malhotra, R (Rahul), Rao, KM, Manios, Y, Mann, JI, Manzato, E, Margozzini, P, Markey, O, Marques-Vidal, P, Marrugat, J, Martin-Prevel, Y, Martorell, R, Masoodi, SR, Matsha, TE, Mazur, A, Mbanya, JCN, McFarlane, SR, McGarvey, ST, McKee, M, McLachlan, S, McLean, RM, McNulty, BA, Yusof, SM, Mediene-Benchekor, S, Meirhaeghe, A, Meisinger, C, Mendes, LL, Menezes, AMB, Mensink, GBM, Meshram, II, Metspalu, A, Mi, J, Michaelsen, KF, Mikkel, K, Miller, JC, Miquel, JF, Misigoj-Durakovic, M, Mohamed, MK, Mohammad, K, Mohammadifard, N, Mohan, V, Yusoff, MFM, Molbo, D, Moller, NC, Molnar, D, Mondo, CK, Monterrubio, EA, Monyeki, KDK, Moreira, LB, Morejon, A, Moreno, LA, Morgan, K, Mortensen, EL, Moschonis, G, Mossakowska, M, Mota, J, Motlagh, ME, Motta, J, Mu, TT, Muiesan, ML, Muller-Nurasyid, M, Murphy, N, Mursu, J, Murtagh, EM, Musa, KI, Musil, V, Nagel, G, Nakamura, H, Namesna, J, Nang, EEK, Nangia, VB, Nankap, M, Narake, S, Navarrete-Munoz, EM, Nenko, I, Neovius, M, Nervi, F, Neuhauser, HK, Nguyen, ND, Nguyen, QN, Nieto-Martinez, RE, Ning, G, Ninomiya, T, Nishtar, S, Noale, M, Norat, T, Noto, D, Al Nsour, M, O'Reilly, D, Ochoa-Aviles, AM, Oh, K, Olayan, IH, Olinto, MTA, Oltarzewski, M, Omar, MA, Onat, A, Ordunez, P, Ortiz, AP, Osler, M, Osmond, C, Ostojic, SM, Otero, JA, Overvad, K, Paccaud, FM, Padez, C, Pajak, A, Palli, D, Palloni, A, Palmieri, L, Panda-Jonas, S, Panza, F, Parnell, WR, Parsaeian, M, Pednekar, MS, Peeters, PH, Peixoto, SV, Pereira, AC, Perez, CM (Cynthia), Peters, A, Peykari, N, Pham, ST, Pigeot, I, Pikhart, H, Pilav, A, Pilotto, L, Pistelli, F, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubio, P, Poh, BK, Porta, M, Portegies, Marileen, Poulimeneas, D, Pradeepa, R, Prashant, M, Price, JF, Puiu, M, Punab, M, Qasrawi, RF, Qorbani, M, Bao, TQ, Radic, I, Radisauskas, R, Rahman, M, Raitakari, O, Raj, M, Rao, SR, Ramachandran, A, Ramke, J, Ramos, R, Rampal, S, Rasmussen, F, Redon, J, Reganit, PFM, Ribeiro, R, Riboli, E, Rigo, F, de Wit, TFR, Ritti-Dias, RM, Rivera, JA, Robinson, SM, Robitaille, C, Rodriguez-Artalejo, F, Rodriguez-Perez, MD, Rodriguez-Villamizar, LA, Rojas-Martinez, R, Rojroongwasinkul, N, Romaguera, D, Ronkainen, K, Rosengren, A, Rouse, I, Rubinstein, A, Ruhli, FJ, Rui, O, Ruiz-Betancourt, BS, Horimoto, A, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Salanave, B, Martinez, ES, Salomaa, V, Salonen, JT, Salvetti, M, Sanchez-Abanto, J, Sandjaja, Sans, S, Santos, DA, Santos, O, dos Santos, RN, dos Santos, R, Sardinha, LB, Sarrafzadegan, N, Saum, KU, Savva, SC, Scazufca, M, Rosario, AS, Schargrodsky, H, Schienkiewitz, A, Schmidt, IM, Schneider, IJ, Schultsz, C, Schutte, A, Sein, AA, Senbanjo, IO, Sepanlou, SG, Shalnova, SA, Shaw, JE, Shibuya, K, Shin, YC, Shiri, R, Siantar, R, Sibai, AM, Silva, AM, Silva, DAS, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Smith, MC, Snijder, MB, So, HK, Sobngwi, E, Soderberg, S, Soekatri, MYE, Solfrizzi, V, Sonestedt, E, Sorensen, TIA, Soric, M, Jerome, CS, Soumare, A, Staessen, JA, Starc, G, Stathopoulou, MG, Staub, K, Stavreski, B, Steene-Johannessen, J, Stehle, P, Stein, AD, Stergiou, GS, Stessman, J, Stieber, J, Stockl, D, Stocks, T, Stokwiszewski, J, Stratton, G, Strufaldi, MW, Sun, CA, Sundstrom, J, Sung, YT, Sunyer, J, Suriyawongpaisal, P, Swinburn, BA, Sy, RG, Szponar, L, Tai, ES, Tammesoo, ML, Tamosiunas, A, Tang, L, Tang, X, Tanser, F, Tao, Y, Tarp, J, Tarqui-Mamani, CB, Taylor, A, Tchibindat, F, Thijs, L, Thuesen, B H, Tjonneland, A, Tolonen, HK, Tolstrup, JS, Topbas, M, Topor-Madry, R, Torrent, M, Traissac, P, Trichopoulou, A, Trichopoulos, D, Trinh, OTH, Trivedi, A, Tshepo, L, Tulloch-Reid, MK, Tuomainen, TP, Tuomilehto, J, Tynelius, P, Tzotzas, T, Tzourio, C, Ueda, P, Ukoli, FAM, Ulmer, H, Unal, B, Valdivia, G, Vale, S, Valvi, D, van der Schouw, YT, Van Herck, K, Minh, HV, van Valkengoed, IGM, Vanderschueren, D, Vanuzzo, D, Vatten, L, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, WMM, Viegi, G, Viet, L, Viikari-Juntura, E, Vineis, P, Vioque, J, Virtanen, JK, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Vrijheid, M, Wade, AN, Wagner, A, Walton, J, Mohamud, WNW, Wang, MD, Wang, Q, Wang, YX, Wannamethee, SG, Wareham, N, Weerasekera, D, Whincup, PH, Widhalm, K, Widyahening, IS, Wiecek, A, Wilks, RJ, Willeit, J, Wojtyniak, B, Wong, JE, Wong, TY, Woo, J, Woodward, M, Wu, FC, Wu, JF, Wu, SL, Xu, HQ, Xu, L, Yamborisut, U, Yan, WL, Yang, XG, Yardim, N, Ye, XW, Yiallouros, PK, Yoshihara, A, You, QS, Younger-Coleman, NO, Yusoff, AF, Zainuddin, AA, Zambon, S, Zdrojewski, T, Zeng, Yaping, Zhao, D (Dan), Zhao, WH, Zheng, YF, Zhou, MG, Zhu, D, Zimmermann, E, and Cisneros, JZ
Published: 2016

9. Better outcomes of peritoneal dialysis in diabetic patients in spite of risk of loss of autonomy for home dialysis

Author: Cotovio, P, Rocha, A, Carvalho, MJ, Teixeira, L, Mendonça, D, Cabrita, A, Rodrigues, A, and Instituto de Saúde Pública
Subjects: Peritoneal dialysis, Diabetes
Abstract: Introduction: Diabetes mellitus is a leading cause of chronic renal failure, challenging therapy strategies. Patients with diabetes may benefit from peritoneal dialysis (PD) but higher technique failure is feared. Our purpose was to critically evaluate clinical outcomes of this modality in diabetics, in order to find quality improvement strategies in these risk patients. Methods: A registry-based study of 432 incident patients, 23% with diabetes, from a university hospital PD program was performed. Traditional methods (Kaplan-Meier, Cox models) and innovative survival analysis, taking competing risks into account, were performed, as well as exploring the trends in cohorts according to the decade of PD start. Results: In spite of the detrimental effect of diabetes in patient survival compared to non-diabetics (77%, 52% vs 86%, 71%, at 2 and 4 years, respectively; p < 0.0001) the hazard ratio (HR) for death decreased in the more contemporary cohort (0.303, 95% confidence interval (CI) 0.150 - 0.614, p < 0.001). It is noteworthy that diabetes was not associated with lower technique survival: 74%, 51% vs 79%, 57%, at 2 and 4 years, respectively (p = not significant (NS)). On multivariate analysis, diabetes was an independent predictor for mortality, but not for technique failure. The hazard ratio (HR) for technique failure also decreased in the more recent cohort (0.566, 95% CI 0.348 - 0.919, p = 0.021). Among reasons for transfer to hemodialysis, proportion of ultrafiltration failure was similar between groups (26% vs 22%, p = NS), but drop-out due to loss of autonomy occurred more in the group with diabetes (23% vs 5%, p = 0.004), mainly due to ischemic stroke. The hospitalization rate was also higher in diabetic patients (1.39 vs 0.84 episodes per patient-year (E/PY), p = 0.004) but the peritonitis rate was not increased (0.53 vs 0.61 E/PY, p = NS). Conclusion: PD was an effective long-term renal replacement therapy in diabetics, without higher rates of technique failure, ultrafiltration failure or peritonitis. Better outcomes were achieved in the contemporary cohort. The menace of autonomy loss due to stroke and higher hospitalization rates enhance the need for assisted PD strategies and better control of comorbidities.
Published: 2014

10. Diurnal Blood Pressure Variation in Progressive Autonomic Failure

Author: Anton H. van den Meiracker, António Freitas, Arie J. Man in 't Veld, M.J. Lima, João Freitas, Carvalho Mj, and Frans Boomsma
Subjects: Adult, Male, medicine.medical_specialty, medicine.medical_treatment, Shy-Drager Syndrome, Hemodynamics, Blood Pressure, Autonomic Nervous System, Internal medicine, Heart rate, Internal Medicine, medicine, Valsalva maneuver, Humans, Circadian rhythm, Pure autonomic failure, business.industry, Diurnal temperature variation, Middle Aged, medicine.disease, Circadian Rhythm, Autonomic nervous system, Endocrinology, Blood pressure, Female, business
Abstract: Abstract —To investigate the role of the autonomic nervous system (ANS) in the generation of the circadian blood pressure (BP) variation, the degree of impairment of the ANS was related to the results of ambulatory BP recordings in 212 patients with progressive autonomic failure due to familial amyloid polyneuropathy. On the basis of BP and/or heart rate (HR) responses to the Valsalva maneuver, 60° head-up tilting, deep-breathing tests, and plasma norepinephrine levels, 4 groups of patients were distinguished. In all patients and in 38 age-matched control subjects, ambulatory BP was monitored. Patients of group I (n=40, aged 32±3 y), with no evidence yet of impairment of their ANS, had circadian BP and HR variations indistinguishable from controls. Patients of group II (n=41, aged 34±5 y) had a variable degree of impairment of their parasympathetic ANS, but their sympathetic ANS was still intact. Twenty-four–hour HR was higher in these patients than in controls (88±11 versus 78±7 bpm, P P
Published: 2000

11. Impaired arterial baroreceptor sensitivity before tilt-induced syncope

Author: A. Falcão de Freitas, Carvalho Mj, João Freitas, Ovídio Costa, P. Lago, and Sonia Maria Miranda Pereira
Subjects: Adult, medicine.medical_specialty, Cardiac output, Baroreceptor, Hemodynamics, Blood Pressure, Pressoreceptors, Heart Rate, Tilt-Table Test, Physiology (medical), Internal medicine, Heart rate, Syncope, Vasovagal, medicine, Humans, Heart rate variability, Vasovagal syncope, business.industry, Middle Aged, medicine.disease, Blood pressure, medicine.anatomical_structure, Anesthesia, Vascular resistance, Cardiology, Cardiology and Cardiovascular Medicine, business
Abstract: Autonomic dysfunction seems to play a central role in the pathophysiology of neurocardiogenic syncope (NCS) but conflicting data have recently become available. We evaluated autonomic nervous system (ANS) function (heart rate variability (HRV), systolic blood pressure variability (SBPV) and baroreceptor gain (BRG)) and non-invasive haemodynamics (cardiac output and total peripheral resistance) in patients with neurocardiogenic syncope. Retrospectively, we evaluated 12 NCS patients (positive head-up tilt without pharmacological provocation) in the basal state and at initial tilt, 12 non-NCS patients with tilt-negative syncope and 12 aged-matched normal controls. Prospectively, we evaluated 16 NCS patients to analyse the haemodynamics and ANS activity throughout the tilt test (beginning of tilt and before syncope occurs). HRV and SBPV were accessed by fast Fourier transforms (FFT) and spontaneous BRG by temporal sequences, slope and a index. Modelflow was used to quantify the non-invasive haemodynamics. None of the autonomic and haemodynamic parameters at baseline or in the first 10 min of tilt was different among the respective NCS, non-NCS syncope and normal control groups, except for SBP, which was higher at baseline in controls. Throughout the tilt test in the prospective NCS group, the heart rate increased (88-95 beats x min(-1), P
Published: 1999

12. Role of Sympathetic Nervous System in Cyclosporine-Induced Rise in Blood Pressure

Author: Anton H. van den Meiracker, João Freitas, Carvalho Mj, Frans Boomsma, Arie J. Man in 't Veld, António Freitas, and Ovídio Costa
Subjects: Adult, medicine.medical_specialty, Sympathetic nervous system, Sympathetic Nervous System, medicine.medical_treatment, Blood Pressure, Liver transplantation, Amyloid Neuropathies, Severity of Illness Index, Internal medicine, Internal Medicine, medicine, Humans, Postoperative Period, Whole blood, Chemotherapy, business.industry, Ciclosporin, medicine.disease, Circadian Rhythm, Liver Transplantation, Blood pressure, Endocrinology, medicine.anatomical_structure, Toxicity, Cyclosporine, Cardiology, Nervous System Diseases, business, Polyneuropathy, Immunosuppressive Agents, medicine.drug
Abstract: Abstract —To clarify the role of the sympathetic nervous system in the development of cyclosporine A (CsA)-induced rise in blood pressure (BP), the effects of CsA on 24-hour ambulatory BP (ABP) were studied in patients with familial amyloid polyneuropathy (FAP) who underwent a liver transplantation. On the basis of autonomic function tests, patients with absent or mild-to-moderate sympathetic damage (Group A, n=11, age 29 to 43 years, disease duration 2 to 6 years) and patients with severe sympathetic damage (Group B, n=9, age 27 to 38 years, disease duration 3 to 9 years) were identified. Both groups were followed for 1 year. The daily doses of CsA and the CsA whole blood trough levels between the groups did not differ. Pretransplantation values of daytime and nighttime ABP were, respectively, 117±8/76±7 mm Hg and 108±12/68±9 mm Hg in group A and 107±6/66±4 mm Hg ( P P P
Published: 1999

13. Investigating Compliance with Standard Precautions During Residency Physicians in Gynecology and Obstetrics

Author: Carvalho, MJ, primary, Pereira, FM, additional, Gir, E, additional, Lam, SC, additional, and Barbosa, CP, additional
Published: 2016
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14. Effects of diabetes definition on global surveillance of diabetes prevalence and diagnosis: a pooled analysis of 96 population-based studies with 331288 participants

Author: Danaei, G, Fahimi, S, Lu, Y, Zhou, B, Hajifathalian, K, Di Cesare, M, Lo, W-C, Reis-Santos, B, Cowan, MJ, Shaw, JE, Bentham, J, Lin, JK, Bixby, H, Magliano, D, Bovet, P, Miranda, JJ, Khang, Y-H, Stevens, GA, Riley, LM, Ali, MK, Ezzati, M, Abdeen, ZA, Kadir, KA, Abu-Rmeileh, NM, Acosta-Cazares, B, Aekplakorn, W, Aguilar-Salinas, CA, Ahmadvand, A, Al Nsour, M, Alkerwi, A, Amouyel, P, Andersen, LB, Anderssen, SA, Andrade, DS, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicova, M, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barcelo, A, Batieha, AM, Baur, LA, Ben Romdhane, H, Bernabe-Ortiz, A, Bhargava, SK, Bi, Y, Bjerregaard, P, Bjorkelund, C, Blake, M, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Brajkovich, I, Breckenkamp, J, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, de Leon, AC, Can, G, Candido, APC, Capuano, V, Carvalho, MJ, Casanueva, FF, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, C-J, Chen, F, Chen, S, Cheng, C-Y, Chetrit, A, Chiou, S-T, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, la Penaa, JE-D, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernandez-Berges, D, Ferrari, M, Ferreccio, C, Finn, JD, Foger, B, Foo, LH, Fouad, HM, Francis, DK, Franco, MDC, Franco, OH, Frontera, G, Furusawa, T, Gaciong, Z, Galbarczyk, A, Garnett, SP, Gaspoz, J-M, Gasull, M, Gates, L, Geleijnse, JM, Ghasemain, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Gross, MG, Rivas, JPG, Gorbea, MB, Gottrand, F, Grant, JF, Grodzicki, T, Grontved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hardy, R, Kumar, RH, He, J, Heidemann, C, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Russo, ARV, Hormiga, CM, Horta, BL, Houti, L, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Kiechl, S, Kim, J, Kiyohara, Y, Kolsteren, P, Korrovits, P, Koskinen, S, Kratzer, W, Kromhout, D, Kula, K, Kurjata, P, Kyobutungi, C, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimaki, T, Lekhraj, R, Leon-Munoz, LM, Li, Y, Lim, W-Y, Lima-Costa, MF, Lin, H-H, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Lundqvist, A, Lytsy, P, Ma, G, Machado-Coelho, GLL, Machi, S, Maggi, S, Makdisse, M, Rao, KM, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Matsha, TE, Mbanya, JCN, McFarlane, SR, McGarvey, ST, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AMB, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohan, V, Yusoff, MFM, Moller, NC, Molnar, D, Mondo, CK, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Muiesan, ML, Muller-Nurasyid, M, Mursu, J, Nagel, G, Namesna, J, Nang, EEK, Nangia, VB, Navarrete-Munoz, EM, Ndiaye, NC, Nervi, F, Nguyen, ND, Nieto-Martinez, RSE, Ning, G, Ninomiya, T, Noale, M, Noto, D, Ochoa-Aviles, AM, Oh, K, Onat, A, Osmond, C, Otero, JA, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pereira, AC, Peters, A, Peykari, N, Pilav, A, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubio, P, Porta, M, Portegies, MLP, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Raitakari, O, Rao, SR, Ramachandran, A, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PFM, Rigo, F, Robinson, SM, Robitaille, C, Rodriguez, LA, Rodriguez-Artalejo, F, Rodriguez-Perez, MDC, Rojas-Martinez, R, Romaguera, D, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sanchez-Abanto, J, Nunes, R, Santos, R, Sardinha, LB, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stockl, D, Stokwiszewski, J, Strufaldi, MW, Sun, C-A, Sundstrom, J, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tarawneh, M, Tarqui-Mamani, CB, Thijs, L, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OTH, Tulloch-Reid, MK, Tuomainen, T-P, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FM, Ulmer, H, Valdivia, G, Van Valkengoed, IGM, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, M, Vioque, J, Virtanen, J, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Wade, AN, Wagner, A, Walton, J, Mohamud, WNW, Wang, M-D, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wilks, RJ, Willeit, J, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, AG, Wu, FC, Wu, SL, Xu, H, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, Zheng, Y, Danaei, G, Fahimi, S, Lu, Y, Zhou, B, Hajifathalian, K, Di Cesare, M, Lo, W-C, Reis-Santos, B, Cowan, MJ, Shaw, JE, Bentham, J, Lin, JK, Bixby, H, Magliano, D, Bovet, P, Miranda, JJ, Khang, Y-H, Stevens, GA, Riley, LM, Ali, MK, Ezzati, M, Abdeen, ZA, Kadir, KA, Abu-Rmeileh, NM, Acosta-Cazares, B, Aekplakorn, W, Aguilar-Salinas, CA, Ahmadvand, A, Al Nsour, M, Alkerwi, A, Amouyel, P, Andersen, LB, Anderssen, SA, Andrade, DS, Anjana, RM, Aounallah-Skhiri, H, Aris, T, Arlappa, N, Arveiler, D, Assah, FK, Avdicova, M, Balakrishna, N, Bandosz, P, Barbagallo, CM, Barcelo, A, Batieha, AM, Baur, LA, Ben Romdhane, H, Bernabe-Ortiz, A, Bhargava, SK, Bi, Y, Bjerregaard, P, Bjorkelund, C, Blake, M, Blokstra, A, Bo, S, Boehm, BO, Boissonnet, CP, Brajkovich, I, Breckenkamp, J, Brewster, LM, Brian, GR, Bruno, G, Bugge, A, de Leon, AC, Can, G, Candido, APC, Capuano, V, Carvalho, MJ, Casanueva, FF, Caserta, CA, Castetbon, K, Chamukuttan, S, Chaturvedi, N, Chen, C-J, Chen, F, Chen, S, Cheng, C-Y, Chetrit, A, Chiou, S-T, Cho, Y, Chudek, J, Cifkova, R, Claessens, F, Concin, H, Cooper, C, Cooper, R, Costanzo, S, Cottel, D, Cowell, C, Crujeiras, AB, D'Arrigo, G, Dallongeville, J, Dankner, R, Dauchet, L, de Gaetano, G, De Henauw, S, Deepa, M, Dehghan, A, Dhana, K, Di Castelnuovo, AF, Djalalinia, S, Doua, K, Drygas, W, Du, Y, Egbagbe, EE, Eggertsen, R, El Ati, J, Elosua, R, Erasmus, RT, Erem, C, Ergor, G, Eriksen, L, la Penaa, JE-D, Fall, CH, Farzadfar, F, Felix-Redondo, FJ, Ferguson, TS, Fernandez-Berges, D, Ferrari, M, Ferreccio, C, Finn, JD, Foger, B, Foo, LH, Fouad, HM, Francis, DK, Franco, MDC, Franco, OH, Frontera, G, Furusawa, T, Gaciong, Z, Galbarczyk, A, Garnett, SP, Gaspoz, J-M, Gasull, M, Gates, L, Geleijnse, JM, Ghasemain, A, Giampaoli, S, Gianfagna, F, Giovannelli, J, Gross, MG, Rivas, JPG, Gorbea, MB, Gottrand, F, Grant, JF, Grodzicki, T, Grontved, A, Gruden, G, Gu, D, Guan, OP, Guerrero, R, Guessous, I, Guimaraes, AL, Gutierrez, L, Hardy, R, Kumar, RH, He, J, Heidemann, C, Hihtaniemi, IT, Ho, SY, Ho, SC, Hofman, A, Russo, ARV, Hormiga, CM, Horta, BL, Houti, L, Hussieni, AS, Huybrechts, I, Hwalla, N, Iacoviello, L, Iannone, AG, Ibrahim, MM, Ikeda, N, Ikram, MA, Irazola, VE, Islam, M, Iwasaki, M, Jacobs, JM, Jafar, T, Jasienska, G, Jiang, CQ, Jonas, JB, Joshi, P, Kafatos, A, Kalter-Leibovici, O, Kasaeian, A, Katz, J, Kaur, P, Kavousi, M, Kelishadi, R, Kengne, AP, Kersting, M, Khader, YS, Kiechl, S, Kim, J, Kiyohara, Y, Kolsteren, P, Korrovits, P, Koskinen, S, Kratzer, W, Kromhout, D, Kula, K, Kurjata, P, Kyobutungi, C, Lachat, C, Laid, Y, Lam, TH, Landrove, O, Lanska, V, Lappas, G, Laxmaiah, A, Leclercq, C, Lee, J, Lehtimaki, T, Lekhraj, R, Leon-Munoz, LM, Li, Y, Lim, W-Y, Lima-Costa, MF, Lin, H-H, Lin, X, Lissner, L, Lorbeer, R, Lozano, JE, Lundqvist, A, Lytsy, P, Ma, G, Machado-Coelho, GLL, Machi, S, Maggi, S, Makdisse, M, Rao, KM, Manios, Y, Manzato, E, Margozzini, P, Marques-Vidal, P, Martorell, R, Masoodi, SR, Matsha, TE, Mbanya, JCN, McFarlane, SR, McGarvey, ST, McLachlan, S, McNulty, BA, Mediene-Benchekor, S, Meirhaeghe, A, Menezes, AMB, Merat, S, Meshram, II, Mi, J, Miquel, JF, Mohamed, MK, Mohammad, K, Mohan, V, Yusoff, MFM, Moller, NC, Molnar, D, Mondo, CK, Moreno, LA, Morgan, K, Moschonis, G, Mossakowska, M, Mostafa, A, Mota, J, Muiesan, ML, Muller-Nurasyid, M, Mursu, J, Nagel, G, Namesna, J, Nang, EEK, Nangia, VB, Navarrete-Munoz, EM, Ndiaye, NC, Nervi, F, Nguyen, ND, Nieto-Martinez, RSE, Ning, G, Ninomiya, T, Noale, M, Noto, D, Ochoa-Aviles, AM, Oh, K, Onat, A, Osmond, C, Otero, JA, Palmieri, L, Panda-Jonas, S, Panza, F, Parsaeian, M, Peixoto, SV, Pereira, AC, Peters, A, Peykari, N, Pilav, A, Pitakaka, F, Piwonska, A, Piwonski, J, Plans-Rubio, P, Porta, M, Portegies, MLP, Poustchi, H, Pradeepa, R, Price, JF, Punab, M, Qasrawi, RF, Qorbani, M, Raitakari, O, Rao, SR, Ramachandran, A, Ramos, R, Rampal, S, Rathmann, W, Redon, J, Reganit, PFM, Rigo, F, Robinson, SM, Robitaille, C, Rodriguez, LA, Rodriguez-Artalejo, F, Rodriguez-Perez, MDC, Rojas-Martinez, R, Romaguera, D, Rosengren, A, Rubinstein, A, Rui, O, Ruiz-Betancourt, BS, Rutkowski, M, Sabanayagam, C, Sachdev, HS, Saidi, O, Sakarya, S, Salanave, B, Salonen, JT, Salvetti, M, Sanchez-Abanto, J, Nunes, R, Santos, R, Sardinha, LB, Scazufca, M, Schargrodsky, H, Scheidt-Nave, C, Shibuya, K, Shin, Y, Shiri, R, Siantar, R, Sibai, AM, Simon, M, Simons, J, Simons, LA, Sjostrom, M, Slowikowska-Hilczer, J, Slusarczyk, P, Smeeth, L, Snijder, MB, Solfrizzi, V, Sonestedt, E, Soumare, A, Staessen, JA, Steene-Johannessen, J, Stehle, P, Stein, AD, Stessman, J, Stockl, D, Stokwiszewski, J, Strufaldi, MW, Sun, C-A, Sundstrom, J, Suriyawongpaisal, P, Sy, RG, Tai, ES, Tarawneh, M, Tarqui-Mamani, CB, Thijs, L, Tolstrup, JS, Topbas, M, Torrent, M, Traissac, P, Trinh, OTH, Tulloch-Reid, MK, Tuomainen, T-P, Turley, ML, Tzourio, C, Ueda, P, Ukoli, FM, Ulmer, H, Valdivia, G, Van Valkengoed, IGM, Vanderschueren, D, Vanuzzo, D, Vega, T, Velasquez-Melendez, G, Veronesi, G, Verschuren, M, Vioque, J, Virtanen, J, Visvikis-Siest, S, Viswanathan, B, Vollenweider, P, Voutilainen, S, Wade, AN, Wagner, A, Walton, J, Mohamud, WNW, Wang, M-D, Wang, YX, Wannamethee, SG, Weerasekera, D, Whincup, PH, Widhalm, K, Wiecek, A, Wilks, RJ, Willeit, J, Wojtyniak, B, Wong, TY, Woo, J, Woodward, M, Wu, AG, Wu, FC, Wu, SL, Xu, H, Yang, X, Ye, X, Yoshihara, A, Younger-Coleman, NO, Zambon, S, Zargar, AH, Zdrojewski, T, Zhao, W, and Zheng, Y
Abstract: BACKGROUND: Diabetes has been defined on the basis of different biomarkers, including fasting plasma glucose (FPG), 2-h plasma glucose in an oral glucose tolerance test (2hOGTT), and HbA1c. We assessed the effect of different diagnostic definitions on both the population prevalence of diabetes and the classification of previously undiagnosed individuals as having diabetes versus not having diabetes in a pooled analysis of data from population-based health examination surveys in different regions. METHODS: We used data from 96 population-based health examination surveys that had measured at least two of the biomarkers used for defining diabetes. Diabetes was defined using HbA1c (HbA1c ≥6·5% or history of diabetes diagnosis or using insulin or oral hypoglycaemic drugs) compared with either FPG only or FPG-or-2hOGTT definitions (FPG ≥7·0 mmol/L or 2hOGTT ≥11·1 mmol/L or history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated diabetes prevalence, taking into account complex survey design and survey sample weights. We compared the prevalences of diabetes using different definitions graphically and by regression analyses. We calculated sensitivity and specificity of diabetes diagnosis based on HbA1c compared with diagnosis based on glucose among previously undiagnosed individuals (ie, excluding those with history of diabetes or using insulin or oral hypoglycaemic drugs). We calculated sensitivity and specificity in each survey, and then pooled results using a random-effects model. We assessed the sources of heterogeneity of sensitivity by meta-regressions for study characteristics selected a priori. FINDINGS: Population prevalence of diabetes based on FPG-or-2hOGTT was correlated with prevalence based on FPG alone (r=0·98), but was higher by 2-6 percentage points at different prevalence levels. Prevalence based on HbA1c was lower than prevalence based on FPG in 42·8% of age-sex-survey groups and higher in another 41·6%; in the other 15·6%, the two
Published: 2015

15. Improved orthostatic tolerance in familial amyloidotic polyneuropathy with unnatural noradrenaline precursor l-threo-3,4-dihydroxyphenylserine

Author: Carvalho Mj, João Freitas, A. Falcão de Freitas, A. H. Van Den Meiracker, F. Boomsma, Ovídio Costa, A. J. Man In 'T Veld, and Internal Medicine
Subjects: Adult, Male, medicine.medical_specialty, Supine position, Physiology, Amyloid Neuropathies, Norepinephrine (medication), Hypotension, Orthostatic, Norepinephrine, Orthostatic vital signs, Internal medicine, Humans, Medicine, Pure autonomic failure, Dose-Response Relationship, Drug, business.industry, General Neuroscience, medicine.disease, Autonomic nervous system, Endocrinology, Blood pressure, Droxidopa, Anesthesia, Female, Neurology (clinical), Complication, business, Polyneuropathy, medicine.drug
Abstract: Disabling orthostatic hypotension, due to insufficiency of the autonomic nervous system, is a common complication of type I familial amyloidotic polyneuropathy (FAP). We investigated whether oral treatment with L-threo-3,4-dihydroxyphenylserine (L-threo-Dops), a noradrenaline precursor, might be of therapeutical benefit. In twenty untreated FAP patients, aged 33 to 44 years, who, because of severe orthostatic hypotension, were bedridden or constrained to a sitting life, supine and erect blood pressure (BP), plasma noradrenaline and tilting time, defined as the interval (s) between the beginning of a 60 degrees head-up tilt and the occurrence of orthostatic symptoms (dizziness, blurred vision or near syncope) were determined before and at repeated intervals during oral treatment with L-threo-Dops, 100 mg bid, for 6 months. Before treatment supine mean BP was 80 (76-85) mmHg (mean and 95% CI), supine plasma noradrenaline was low, 59 (41-77) pg/ml and tilting time ranged from 38 to 118 s. In response to tilt, mean BP immediately fell by 36 (31-41) mmHg, whereas plasma noradrenaline increased by only 11 (0-21) pg/ml (p = 0.05). After 3 to 5 days of treatment with L-threo-Dops all patients experienced marked improvement of their orthostatic tolerance as reflected by their ability to walk freely around. This effect sustained throughout the six months of treatment. Plasma noradrenaline increased moderately by 37 (11-63) pg/ml (p = 0.02) and supine mean BP increased by 8.6 (5.8-12.4) mmHg (p0.001) during chronic treatment. Supine or nocturnal hypertension did not develop, the fall in mean BP in response to tilt diminished by 12.5 (6.5-17.3) mmHg (p0.001) and tilting time became longer than 600 s in all patients. Because of its efficacy, its sustained duration of action and the lack of side effects, L-threo-Dops is advocated to improve orthostatic tolerance in patients with autonomic insufficiency due to FAP.
Published: 1997

16. Improving crunchiness and crispness of fried squid rings through innovative tempura coatings: addition of alcohol and CO2 incubation.

Author: Carvalho, MJ and Ruiz-Carrascal, J.
Abstract: This study aimed to determine the effect of different uncommon tempura formulations (incubated with CO2 and with added ethanol) on physical, chemical and sensory characteristics of fried coated squids, immediately after frying and also after 48 h of refrigeration storage and subsequent oven reheating. Ethanol addition led to lower levels of moisture and higher of fat in the fried coating, regardless the use of CO2. There were no difference in instrumental colour parameters among all four battered samples. Ethanol added tempuras showed higher crispness and lower maximum force than their water counterparts in an instrumental texture evaluation. Fried squids coated with ethanol added tempuras were rated as crispier and crunchier, even after 2 days of storage and further reheating. Overall, partial substitution of water by ethanol appears as an interesting strategy to increase crispness in tempura coated fried products, especially when the products are stored and reheated before consumption. [ABSTRACT FROM AUTHOR]
Published: 2018
Full Text: View/download PDF

17. Heart rate variability in 24-hour holter recordings

Author: Ovídio Costa, Adelaide Brandão, António Freitas, Carvalho Mj, Puig J, João Freitas, Ana Paula Rocha, Falcao de Freitas, and P. Lago
Subjects: medicine.medical_specialty, Series (stratigraphy), medicine.diagnostic_test, business.industry, Standard deviation, Surgery, Frequency domain, Statistics, Heart rate, medicine, Heart rate variability, Every Hour, Very low frequency, Cardiology and Cardiovascular Medicine, business, Electrocardiography
Abstract: Mean hourly parameters obtained from all beats (long series) were compared with those obtained from a sample of 512 beats extracted each hour (short series) in nine presumably normal subjects. For both the short and long series, the spectral components, very low frequency, (VLF), low frequency (LF), and high frequency (HF), and time-domain indices (such as the Ewing statistic [PNN50] and RR standard deviation [SD-RR]), have been estimated. The spectral components LF and HF, estimated from the short and long series, were not significantly different, whereas significant differences were found between VLF, SD--RR, and PNN50. In both the short and long series, a strong correlation was found between LF and SD-RR and between HF and PNN50. The results suggest that, over a period of 24 hours, hourly LF and HF spectral components can be obtained using a single series of 512 beats every hour, with a great advantage over the evaluation of the mean hourly parameters. This method would be particularly useful in the study of circadian heart rate spectral analysis in Holter recordings with multiple artifacts or ectopic beats, and in general, when analysis of the entire 24-hour series is not feasible.
Published: 1994

18. FP567PERITONEAL DIALYSIS DROP-OUT IN CONTEMPORARY COHORT: LOWER TECHNIQUE FAILURE AND HIGHER TRANSPLANTATION RATE

Author: Campos, Andreia, primary, Teixeira, Laetitia, additional, Carvalho, MJ, additional, Santos, Sofia, additional, Cabrita, A, additional, and Rodrigues, A, additional
Published: 2015
Full Text: View/download PDF

19. Metallo-beta-lactamase in clinical Pseudomonas aeruginosa isolate in a Portuguese hospital and identification of a new VIM-2 like enzyme

Author: Carvalho, MJ, Saavedra, MJ, Correia, A, Castro, AP, Duarte, A, and Repositório da Universidade de Lisboa
Abstract: Made available in DSpace on 2015-12-30T10:19:16Z (GMT). No. of bitstreams: 0 Previous issue date: 2005
Published: 2005

20. Endometriose e Infertilidade. Revisão das Formas de Terapêutica

Author: Vicente, L, Sobral, D, Pinto, G, Maia, A, Neves, A, and Carvalho, MJ
Subjects: Procriação, Infertilidade, Endometriose
Abstract: Procedeu-se a uma revisão da literatura sobre os conceitos actuais de tratamento da endometriose associada a infertilidade. A terapêutica médica isolada não parece ser útil no tratamento da infertilidade. A cirurgia laparoscópica permite melhorar a probabilidade de ocorrência de gravidez espontânea ou com auxílio de técnicas de procriação medicamente assistida (PMA). Um estudo prospectivo demonstrou o efeito benéfico do tratamento cirúrgico da endometriose I e II. A cirurgia dos endometriomas do ovário com dimensões superiores a 3 cm não está associada a diminuição da reserva folicular do ovário, permitindo a ocorrência de gravidezes espontâneas, principalmente durante o primeiro ano após a sua realização. Quando se planeia a realização de técnicas de PMA, a utilização de protocolos de GnRH ultra-longos está indicada nos estádios III e IV de endometriose, por aumentar significativamente as taxas de gravidez evolutiva, benefício que não se verifica nos estádios I e II de endometriose.
Published: 2003

21. Ainda Há Lugar Para a Recanalização Tubária? Casuística da Unidade de Medicina de Reprodução (UMR) da Maternidade Dr. Alfredo da Costa (MAC) dos anos 1995 a 2002

Author: Santos, L, Remesso, L, Pargana, L, Neves, A, and Carvalho, MJ
Subjects: Laqueação Tubária, Gravidez, MAC GIN
Abstract: A laqueação tubária bilateral (LTB) é um dos métodos de contracepção mais solicitados, sendo considerado definitivo. Contudo em cerca 3-5% de todas as mulheres que realizaram LTB vêm posteriormente a desejar uma nova gravidez. O objectivo deste trabalho foi avaliar os resultados obtidos após recanalização tubária realizadas na UMR da MAC e fazer uma breve revisão das condutas seguidas actualmente na abordagem desta situação. Materiais e métodos: Foram avaliadas 15 cirurgias para recanalização tubária por laparotomia no período de Janeiro de 1995 a Março de 2002. A idade média das mulheres à data da recanalização tubária foi de 35.3 anos. Em 3 casos observou-se a presença de 1 ou mais factores de infertilidade associados. Todos os casais foram submetidos a uma avaliação pré-operatória criteriosa. Resultados: Tendo em consideração apenas a 1ª gravidez conseguida verificou-se uma taxa de 62.5% de gravidez intra-uterina (GIU). De acordo com o método de LTB utilizado a probabilidade de ocorrer gravidez mostrou-se diferente sendo maior quando esta foi realizada com anéis de Yoon (1/1) e Pomeroy (6/6) versus nenhum caso de gravidez quando electrocoagulação (0/3). Registaram-se 66.7% GIU nas anastomoses istmo-istmicas vs 50% nas anastomoses istmo-ampolar. A HSG pós-operatória revelou-se um método preditivo da ocorrência de uma gravidez quando dentro dos parâmetros considerados normais. Conclusão: O método de LTB sempre que possível deve ser realizado na zona ístmica e nos casos com a menor destruição possível de trompa. A recanalização tubária e fertilização in vitro (FIV) devem ser considerados procedimentos complementares, sendo a adequada selecção das pacientes crucial para a escolha da melhor abordagem terapêutica.
Published: 2002

22. Síndrome de Klinefelter. Experiência de uma Consulta de Infertilidade

Author: Sabino, T, Gardete Correia, L, Nunes Corrêa, J, Rocha, T, Carvalho, MJ, and Sá e Melo, P
Subjects: MAC HCC, Síndrome de Klinefelter, Consulta, MAC END, MAC GIN, Infertilidade
Abstract: O Síndrome de Klinefelter é uma das causas mais frequentes de hipogonadismo masculino. As manifestações clínicas do Síndrome de Klinefelter variam consideravelmente de indivíduo para indivíduo. Assim, alguns doentes têm alterações no desenvolvimento dos caracteres sexuais secundários, enquanto que outros não se distinguem de indivíduos saudáveis. Os autores avaliaram a variabilidade de apresentação clínica em 25 doentes com S. de Klinefelter, diagnosticados numa consulta de infertilidade.
Published: 2002

23. Gravidez Após Polipectomia por Ressectoscopia

Author: Godinho, C, Neves, A, and Carvalho, MJ
Subjects: Estudos Retrospectivos, Gravidez, Pólipos, MAC GIN
Abstract: As anomalias da cavidade uterina e, nomeadamente os pólipos endometriais, são uma importante causa de subfertilidade. Com o objectivo de determinar um impacto do pólipo endometrial na ocorrência de a gravidez, avaliaram-se retrospectivamente 74 mulheres, da consulta de infertilidade da maternidade Dr. Alfredo da Costa, com aquele diagnóstico e que foram ou não sujeitas a cirurgia correctiva, entre Janeiro de 1997 e Dezembro de 2000. 20 das mulheres apresentavam factores adicionais de infertilidade das quais 14 foram submetidas a técnicas de procriação medicamente assistida (PMA). Considerando as mulheres sem factores adicionais de infertilidade e com factores de infertilidade submetidas a PMA, ocorreram 10 gravidezes entre as 31 mulheres que realizaram polipectomia e 6 entre as 33 que não efectuaram esta cirurgia correctiva, não tendo sida esta diferença estatisticamente significativa. Ocorreram 3 abortos nas mulheres não sujeitas a polipectomia. Não foram detectadas diferenças entre os pólipos com mais ou menos 2cm. Neste estudo parece existir uma relação positiva entre a polipectomia e a ocorrência de gravidez, no entanto para melhor avaliação sugere-se o prolongamento do período e a determinação objectiva do número de gravidezes e o seu desfecho.
Published: 2002

24. Hidrossalpinge e Outras Causas de Factor Tubário Efeito Deletério do Hidrossalpinge?

Author: Ventura, PM, Grilo, I, Maia, AP, Silva, G, Boto, J, Arnold, C, Pires, LC, Carvalho, MJ, and Sá e Melo, P
Subjects: Fertilização In Vitro, Estudos Retrospectivos, Estudo Comparativo, Infertilidade
Abstract: Introdução: A Técnica de fertilização in vitro-transferência embrionária (FIV-TE) foi desenvolvida para permitir a gravidez em mulheres com patologia tubária. Inúmeros artigos foram publicados referindo que no grupo de Infertilidade Feminina por Factor Tubário isolado (FTi), o sub-grupo de Hidrossalpinge (HS), apresentava piores resultados nos ciclos FIV-TE. Material e Métodos: Estudo retrospectivo de 99 ciclos FIV-TE efectuados em 88 mulheres com FTi entre Janeiro de 1997 e Dezembro de 1999, na Unidade de Medicina da Reprodução da Maternidade Dr. Alfredo da Costa (MAC). O objectivo foi comparar as diferentes taxas de gravidez entre o subgrupo de Hidrossalpinge (n=28) e o grupo de FTi sem hidrossalpinge (n=71). Resultados: A análise estatística entre o grupo HS e o grupo de Fti sem HS relativamente aos parâmetros do protocolo FIV foi estatisticamente não significativa. Discussão: Um grande número de estudos na literatura confirmam o efeito negativo do HS nos resultados da técnica FIV-TE, relativamente às outras causas de factor tubário, excepto os estudos de Sharara et al (1996) e Bazar et al (1995). Provavelmente as diferentes técnicas para o diagnóstico do HS resultam em diferentes percentagens de diagnóstico da patologia, interferindo nos resultados finais. Conclusão: Na população em estudo na MAC o efeito deletério do HS não demonstrou significado estatístico. No entanto, em valor absoluto a taxa de gravidez é discretamente inferior.
Published: 2001

25. Importância da Inseminação Artificial na Terapêutica da Infertilidade

Author: Baleiras, C, Neves, A, Arnould, C, Lima, J, Carvalho, MJ, Silva, G, Maia, AP, Oliveira, AP, Pires, LC, and Sá e Melo, P
Subjects: Estudos Retrospectivos, Inseminação Artificial, Estimulação da Ovulação, Taxa de Gravidez, Infertilidade
Abstract: Introdução: Desde há vários anos que a inseminação intra-uterina intra-conjugal (IAC), com ou sem estimulação ovárica, vem sido usada no tratamento da infertilidade. No entanto, o seu uso permanece controverso. Material e métodos: Efectuou-se uma análise retrospectiva (1997-1999) de 114 ciclos de IAC com estimulação ovárica controlada em 66 casais, com o objectivo de determinar a eficácia da IAC e identificar variáveis significativas predictíveis do seu sucesso. Analisou-se o protocolo de estimulação, taxa de gravidez, resultado da gravidez e complicações da terapêutica. Resultados: A taxa de gravidez foi de 10,5% por ciclo e de 18% por casal, sendo a taxa de gravidez múltipla de 25% e a de aborto 0%. Metade de todas as gravidezes resultantes ocorreram no primeiro ciclo de IAC. A análise estatística identificou duas variáveis significativas: número de folículos e duração da infertilidade. Baixas doses de FSH parecem prevenir a gravidez múltipla e o síndrome de hiperestimulação ovárica. Conclusão: Concluímos que uma selecção criteriosa das pacientes associada a estimulação ovárica adequada é fundamental para o sucesso da IAC e que esta técnica constitui um tratamento eficaz para algumas formas de infertilidade.
Published: 2000

26. Anomalias Mullerianas em Infertilidade

Author: Sousa, S, Carvalho, MJ, and Sá e Melo, P
Subjects: Malformações Congénitas, Infertilidade
Abstract: A existência de uma cavidade uterina com tamanho e forma adequadas constitui um pré-requisito para uma gestação com sucesso. As malformações müllerianas parecem ter repercussão na fecundidade do casal, sendo apontadas como causa de aborto recorrente e parto pré-termo. O verdadeiro contributo das malformações uterinas para o insucesso reprodutivo é difícil de avaliar; Não existem certezas absolutas de que a sua correcção cirúrgica melhore o resultado de uma futura gravidez. Os autores fazem uma revisão teórica sobre anomalias müllerianas, sua embriogénese, classificação, apresentação clínica, diagnóstico e indicação cirúrgica.
Published: 2000

27. Diagnóstico Laparoscópico de Endometriose

Author: Marques, AC, Caro, I, Carvalho, MJ, Neves, A, Maia, AP, Oliveira, LC, and Sá-Melo, P
Subjects: Laparoscopia, MAC MED MAF, Estudos Retrospectivos, Endometriose
Abstract: Efectuamos uma análise retrospectiva de 233 laparoscopias realizadas no âmbito da infertilidade, no período compreendido entre Janeiro de 1996 e Dezembro de 1997. Detectou-se Endometriose em 36% dos casos, correspondendo em 65,3% a Endometriose mínima e moderada. Os sintomas clínicos nem sempre se correlacionaram com o estadio anatómico da doença. A taxa de gravidez corrigida após a laparoscopia, avaliada com um recuo mínimo de seis meses foi de 18,1%. info:eu-repo/semantics/publishedVersion
Published: 1999

28. Avaliação e Atitude Terapêutica nos Quistos Endometriais Ováricos

Author: Marques, AC, Carvalho, MJ, Neves, A, Maia, AP, Oliveira, LC, and Sá e Melo, P
Subjects: Laparoscopia, Terapêutica, MAC MED MAF, Endometriose
Abstract: Foram avaliadas 233 laparoscopias realizadas na Unidade de Medicina de Reprodução da Maternidade Dr. Alfredo da Costa no período compreendido entre Janeiro de 1996 e Dezembro de 1997. A prevalência de endometriose foi de 36% com uma incidência de 28,5% de Quistos Endometriais. Confirmou-se na laparoscopia o diagnóstico ecográfico de Quisto Endometrial em 95,8% dos casos. Foram analisados os resultados da atitude terapêutica dos 24 Quistos Endometriais submetidos a laparoscopia cirúrgica. A taxa de recidiva foi de 16,6%. A taxa de gravidez corrigida avaliada com um recuo mínimo de 6 meses foi de 21,0%. info:eu-repo/semantics/publishedVersion
Published: 1999

29. Avaliação dos riscos da infecção pelo HIV segundo diferentes práticas sexuais na perspectiva de estudantes universitários e especialistas em HIV/AIDS

Author: Tokico Murakawa Moriya, Elucir Gir, Marco Antonio de Castro Figueiredo, de Carvalho Mj, and Geraldo Duarte
Subjects: Aids patients, medicine.medical_specialty, business.industry, Síndrome de imunodeficiência adquirida, Varimax rotation, Human immunodeficiency virus (HIV), Human sexuality, medicine.disease_cause, medicine.disease, Comportamento sexual, law.invention, Likert scale, Acquired immunodeficiency syndrome, Condom, Acquired immunodeficiency syndrome (AIDS), law, Family medicine, Health care, Medicine, Sex behavior, business, Estudantes, Students, General Nursing
Abstract: Avaliar as crenças acerca dos graus e riscos atribuídos pelos universitários a diferentes práticas sexuais e comparálas com a atribuição feita por especialistas em AIDS, constituíram o objetivo deste estudo. Um questionário composto por 25 itens (Escala de Probabilidade do tipo Likert), referentes à práticas/hábitos sexuais foi aplicado a alunos dos cursos de graduação em Enfermagem e Obstetrícia, Medicina, Psicologia, Farmácia-Bioquímica, que aquiesceram em respondê-lo. Através deanálise fatorial, usando-se o Sistema Varimax de Rotação, 25 itens foram distribuídos em sete fatores, sendo cinco itens excluídos. Dos 20 itens, 5 foram analisados neste trabalho, compondo dois fatores. O Fator X foi constituído pelos itens 1(sexo vaginal com preservativo) e 2(sexo anal com preservativo). No Fator Y foram alocados os itens: 3(relação com pessoa do sexo oposto), 4(relação vaginal sem preservativo) e 5(sexo anal sem preservativo). Em 80% dos 5 itens, observou-se que os estudantes apresentam conhecimento compatível ao preconizado pelos especialistas. Entretanto faz-se necessária a educação continuada a estes alunos, considerando-os enquanto pessoa e futuro profissional prestador de assistência aos indivíduos infectados pelo HIV ou com AIDS. To detect the beliefs concerning the risk levels related to several sexual practices/habits and the HIV infection among undergraduate students and to compare their opinion with the AIDS experts were the objectives of this study. A 25- item questionnaire (Likert Probability Scale) about sexual practices/habits were answered by undergraduate students enrolled in the courses of nursing, medical school, pharmacy-biochemistry, psychology. Based on Fatorial analysis and by using the Varimax Rotation System, 25 itens were distributed in 7 factors, and 5 itens were excluded. From the 20 itens, 5 were reunited in 2 factors and studied in this paper. Factor X reunited the itens 1 (vaginal intercourse with condom) and 2 (anal sex with condom). In Factor Y the itens included were: 3 (heterosexual intercourse), 4 (vaginal intercourse without condom) and 5 (anal intercourse without condom). In 80% of the 5 itens, it was observed that the students have knowledge similar to the experts"s evidences But, continuing education is necessary to these people, as human beings and as future health care givers to the HIV infected/AIDS patients.
Published: 1999

30. Agenesia Congénita do Colo

Author: Chung, A, Sobral, D, Carvalho, MJ, Neves, A, Pires, L, and Sá e Melo, P
Subjects: Colo do Útero, Amenorreia, MAC GIN, Malformações Congénitas, Infertilidade
Abstract: Submitted by Ana Quininha (ana.quininha@chlc.min-saude.pt) on 2014-06-24T14:53:59Z No. of bitstreams: 1 Arq MAC 1999 111.pdf: 193301 bytes, checksum: d7650085ba05cd9c2e3a34d0a006ae60 (MD5) Made available in DSpace on 2014-06-24T14:53:59Z (GMT). No. of bitstreams: 1 Arq MAC 1999 111.pdf: 193301 bytes, checksum: d7650085ba05cd9c2e3a34d0a006ae60 (MD5) Previous issue date: 1999
Published: 1999

31. Apresentação Pélvica: Parto Vaginal ou Cesariana?

Author: Sousa, S, Vicente, L, Mendes, A, Martins, AT, Maia, AP, Vitorino, A, Sereno, P, Borrego, J, and Carvalho, MJ
Subjects: Parto, Estudos Retrospectivos, Apresentação Pélvica, MAC URG
Abstract: A apresentação pélvica ocorre em 3% das gravidezes únicas de termo e está associada ao aumento do risco de complicações maternas e fetais. Os autores fizeram uma avaliação retrospectiva de 118 partos pélvicos por via vaginal. Foram considerados os recém-nascidos com pesos compreendidos entre 2000 e 4000 g, de gestação maior ou igual a 34 semanas. Comparou-se a morbilidade materna e do recém-nascido com apresentação pélvica, em 118 partos vaginais e 244 cesarianas. Constatou-se que a morbilidade neonatal major foi significativamente superior no parto vaginal (5,9%), em relação à cesariana (0,4%). A morbilidade materna foi ligeiramente superior na cesariana (3,6%), em relação ao parto vaginal (1,6%), sem significado estatístico.
Published: 1999

32. Circadian heart rate variability rhythm in shift workers

Author: João Freitas, Carvalho Mj, Puig J, Ovídio Costa, P. Lago, and A. Falcão de Freitas
Subjects: Adult, Male, medicine.medical_specialty, Holter monitor, Work, Autonomic Nervous System, Shift work, Rhythm, Heart Rate, Internal medicine, Heart rate, medicine, Heart rate variability, Humans, Circadian rhythm, Occupations, Morning, Chronobiology, medicine.diagnostic_test, business.industry, Reproducibility of Results, Circadian Rhythm, Endocrinology, Multivariate Analysis, Cardiology, Electrocardiography, Ambulatory, Cardiology and Cardiovascular Medicine, business
Abstract: The objective of this study was to assess the influence of day-night cycle and sleep-awake period on the circadian pattern of heart rate variability (HRV). Twelve male oil refinery security shift workers, aged 39 +/- 7 years, were studied with 24-hour Holter monitor recordings during morning and night work periods. Hourly HRV parameters in the time and frequency domains were evaluated. For both shifts, all HRV parameters during awake or work periods were found not to be statistically different. In both day and night work shifts, the very low frequency and high-frequency components of HRV and the proportion of differences in successive R-R intervals greater than 50 ms increased during the sleep period, while the low frequency/high frequency ratio decreased. The low-frequency component in absolute units and the SD of the R-R interval did not show any variation in either shifts for the different periods. These results suggest that the circadian pattern of HRV seems to be predominantly related to sleep (supine) and wakefulness (standing) and remains independent of night-day cycle.
Published: 1997

33. DIFFERENT ORTHOSTATIC INTOLERANCE SYNDROMES HAD A NON-SIMILAR HEMODYNAMIC, AUTONOMIC AND NEUROHORMONAL BEHAVIOUR IN AN INITIAL SHORT TERM TEN-MINUTE HEAD-UP TILT EVALUATION

Author: Carvalho Mj, Emilia Teixeira, João Freitas, R. Santos, F. Boomsma, and Anton H. van den Meiracker
Subjects: Physiology, business.industry, Anesthesia, Internal Medicine, medicine, Hemodynamics, Orthostatic intolerance, Head up tilt, Cardiology and Cardiovascular Medicine, medicine.disease, business, Term (time)
Published: 2004

34. A27-1 Orthostatic intolerance syndromes. Hemodynamic, autonomic and neurohormonal behaviour in a ten-minute head-up tilt evaluation

Author: Cassiano Abreu-Lima, A. Meiracker, R. Santos, João Freitas, Carvalho Mj, and Frans Boomsma
Subjects: medicine.medical_specialty, business.industry, Hemodynamics, Orthostatic intolerance, Head up tilt, medicine.disease, Autonomic nervous system, Endocrinology, Physiology (medical), Internal medicine, medicine, Cardiology, Cardiology and Cardiovascular Medicine, business
Published: 2003

35. Avaliação da Eficácia do Citrato de Clomifene na Correcção dos Distúrbios Ovulatórios da Mulher Infértil

Author: Teresinha Ferreira, H, Carvalho, MJ, and Sá Melo, P
Subjects: Ovulação, MAC GIN, Avaliação
Abstract: Submitted by Ana Quininha (ana.quininha@chlc.min-saude.pt) on 2021-11-11T15:24:32Z No. of bitstreams: 1 Artigo pag.42 de 1993 n.º 9.pdf: 304096 bytes, checksum: 3b0968ced47c68f3814dde50111a108d (MD5) Made available in DSpace on 2021-11-11T15:24:32Z (GMT). No. of bitstreams: 1 Artigo pag.42 de 1993 n.º 9.pdf: 304096 bytes, checksum: 3b0968ced47c68f3814dde50111a108d (MD5) Previous issue date: 1993-06 info:eu-repo/semantics/publishedVersion
Published: 1993

36. Avaliação da Morbilidade e Mortalidade no Serviço de Ginecologia da Maternidade Dr. Alfredo da Costa. Jan/Set 1991

Author: Carvalho, MJ, Anjos, F, and Catarino Tavares, E
Subjects: Mortalidade, Morbilidade, MAC GIN
Abstract: Foram avaliados todos os internamentos no Serviço de Ginecologia da MAC de 2 de Janeiro a 19 de Setembro de 1991. O critério de selecção baseou-se no registo de morbilidade intra-operatória e no prolongamento de tempo de internamento. Foram estudados os dados relativos à idade, factores de risco associados, risco anestésico, tipo de intervenção cirúrgica, tempo operatório, tipo de complicações e média de tempo de internamento. Verificou-se uma morbilidade global de 5,6%, tendo-se constatado uma maior incidência de complicações no grupo das histerectomias abdominais (16,8%). Nos casos com morbilidade 72% apresentavam um ou mais factores de risco associados. Ocorreram 5 lesões de órgão (0,73%), 33 complicações pós-operatórias (4,8%) e 7 reintervenções (1%). A média de internamento neste grupo de doentes foi de 11 dias.
Published: 1992

37. Heart rate variability as an assessment of brain death

Author: A. Falcão de Freitas, Carvalho Mj, Elsa Azevedo, Juliana Teixeira, Ovídio Costa, and João Freitas
Subjects: Adult, Male, Brain Death, Transplantation, medicine.medical_specialty, business.industry, Respiration, Blood Pressure, Electrocardiography, Heart Rate, medicine, Humans, Heart rate variability, Female, Surgery, Intensive care medicine, business
Published: 2000

38. Spectral Analysis of R-R Variability in Familial Amyloidotic Polyneuropaty, Andrade Type

Author: Carvalho Mj, Puig J, T. Coelho, Ovídio Costa, João Freitas, Paulo Fernandes, and Falcao de Freitas
Subjects: medicine.medical_specialty, Supine position, business.industry, Group ii, Diaphragmatic breathing, medicine.disease, Intensity (physics), Endocrinology, Internal medicine, Heart rate, medicine, Cardiology, Spectral analysis, business, Polyneuropathy, Asymptomatic carrier
Abstract: Spectral analysis of R-R variability has been done in twenty subjects with Familial Amyloidotic Polyneuropathy in order to define intensity, chronology and discriminative capacity of this method in parasympathetic and sympathetic disturbances. The subjects were subdivided in 3 groups. Group I with far advanced disease, group II in early stages of the disease and group III with asymptomatic carriers. The R-R spectral analysis was calculated after fast Fourier transform in supine and after 60 tilt. Valsalva manoeuvre, deep breathing and standing were performed in groups II and III. The results showed a very severe autonomic disturbance in group I.The parasympathetic system seems to be early affected even in some asymptomatic carriers. Heart rate spectral analysis seems to be more sensitive for detection of autonomic disturbances than other autonomic tests.
Published: 1991

39. Autonomic dysfunction in asymptomatic patients with TTR MET30+

Author: Joao P. Freitas, Anthony V. Meiracker, Carvalho Mj, Frans Boomsma, and Rosa Santos
Subjects: medicine.medical_specialty, Ambulatory blood pressure, biology, business.industry, medicine.disease, Asymptomatic, Autonomic nervous system, Transthyretin, Blood pressure, Internal medicine, Internal Medicine, Cardiology, medicine, biology.protein, Heart rate variability, medicine.symptom, Pure autonomic failure, business
Published: 2005

40. Evoked visual blood flow before and after deep brain stimulation in Parkinson’s disease - a fTCD study

Author: Joao P. Freitas, Rosa Santos, Carvalho Mj, and Elsa Azevedo
Subjects: medicine.medical_specialty, Deep brain stimulation, Parkinson's disease, business.industry, medicine.medical_treatment, Unified Parkinson's disease rating scale, Blood flow, Posterior cerebral artery, medicine.disease, Transcranial Doppler, Subthalamic nucleus, Visual cortex, medicine.anatomical_structure, medicine.artery, Internal medicine, Internal Medicine, medicine, Cardiology, business
Published: 2005

41. 789 Autonomic dysfunction in asymptomatic patients with TTR met30+

Author: J.P. Freitas, A. Meiracker, E. Azevedo, R. Santos, and Carvalho Mj
Subjects: medicine.medical_specialty, Transthyretin, biology, business.industry, Physiology (medical), Internal medicine, medicine, biology.protein, medicine.symptom, Cardiology and Cardiovascular Medicine, business, Gastroenterology, Asymptomatic
Published: 2005

42. IMPROVEMENT ON AUTONOMIC NERVOUS SYSTEM DYSFUNCTION IN OBESE PATIENTS WITHOUT PHARMACOLOGICAL INTERVENTION

Author: Rosa Santos, Joao P. Freitas, M.E. Macedo, Carvalho Mj, Irene Rebelo, and Ana Monteiro
Subjects: medicine.medical_specialty, Autonomic nervous system, Physical medicine and rehabilitation, Physiology, business.industry, Intervention (counseling), Internal Medicine, Physical therapy, Medicine, Cardiology and Cardiovascular Medicine, business
Published: 2004

43. INVERTED ORCADIAN PATTERN AND LOSS OF CHAOTIC SHORT-TERM VARIABILITY ON HEART RATE AND BLOOD PRESSURE IN AUTONOMIC NEUROPATHY

Author: F. Boomsma, Carvalho Mj, Elsa Azevedo, Anton H. van den Meiracker, Francisco Rocha-Gonçalves, R. Santos, João Freitas, and Cassiano Abreu-Lima
Subjects: medicine.medical_specialty, Physiology, business.industry, Short Term Variability, Chaotic, Endocrinology, Blood pressure, Internal medicine, Heart rate, Internal Medicine, medicine, Cardiology, Cardiology and Cardiovascular Medicine, business, Autonomic neuropathy
Published: 2004

44. Hemodynamic, autonomic and neurohormonal behaviour in a ten-minute head-up tilt evaluation in different orthostatic intolerance syndromes

Author: Carvalho Mj, Frans Boomsma, Anthony V. Meiracker, Joao P. Freitas, Francisco R Goncalves, Cassiano Abreu-Lima, Rosa Santos, and Elsa Azevedo
Subjects: medicine.medical_specialty, Supine position, medicine.diagnostic_test, business.industry, Orthostatic intolerance, Hemodynamics, medicine.disease, Autonomic nervous system, Tilt table test, Blood pressure, Internal medicine, Anesthesia, Internal Medicine, medicine, Cardiology, business, Pure autonomic failure, Vasovagal syncope
Published: 2004

45. NEUROHURMONAL BEHAVIOUR THROUGH PROLONGED ORTHOSTATIC STIMULUS IN NORMOTENSIVE SUBJECTS

Author: E. Azevedo, Francisco Rocha-Gonçalves, Carvalho Mj, R. Santos, João Freitas, A. H. Van Den Meiracker, F. Boomsma, and Cassiano Abreu-Lima
Subjects: Orthostatic vital signs, medicine.medical_specialty, Physiology, business.industry, Internal Medicine, medicine, Audiology, Stimulus (physiology), Cardiology and Cardiovascular Medicine, business
Published: 2004

46. Neurohormonal factors in normotensive subjects. Comparison between supine, acute and prolonged orthostatic stimulus

Author: Cassiano A. Lima, Emilia Teixeira, Rosa Santos, Carvalho Mj, A. Meiracker, Frans Boomsma, and Joao P. Freitas
Subjects: Orthostatic vital signs, Supine position, business.industry, Anesthesia, Internal Medicine, Medicine, Stimulus (physiology), business
Published: 2003

47. Effect of prolonged orthostatic stimulus on autonomics and hemodynamics in normotensive subjects

Author: Emilia Teixeira, Carvalho Mj, Frans Boomsma, A. Meiracker, Rosa Santos, Joao P. Freitas, and Cassiano A. Lima
Subjects: Orthostatic vital signs, medicine.medical_specialty, business.industry, Internal medicine, Internal Medicine, Cardiology, Medicine, Hemodynamics, Stimulus (physiology), business
Published: 2003

48. Is pulse pressure independent from autonomics in mild hypertension?

Author: Rosa Santos, Joao P. Freitas, Carvalho Mj, António Freitas, Maria E. Teixeira, and M.J. Lima
Subjects: medicine.medical_specialty, Ambulatory blood pressure, Baroreceptor, business.industry, Hemodynamics, Prehypertension, Pulse pressure, Blood pressure, Anesthesia, Internal medicine, Heart rate, Internal Medicine, medicine, Cardiology, Systole, business
Published: 2002

49. Hyperthyroidism sinus tachycardia. Sympathetic stimulation or vagal inhibition?

Author: A. Falcão de Freitas, Ovídio Costa, João Freitas, Rosa Santos, Carvalho Mj, and J.L. Medina
Subjects: Sympathetic stimulation, medicine.medical_specialty, business.industry, Sinus tachycardia, Internal medicine, Vagal escape, Internal Medicine, medicine, Cardiology, medicine.symptom, business
Published: 1999

50. Obesity, high blood pressure and autonomic nervous system

Author: João Freitas, AFalcão de Freitas, Carvalho Mj, Rosa Santos, and M.E. Macedo
Subjects: medicine.medical_specialty, Autonomic nervous system, Blood pressure, business.industry, Internal medicine, Pathophysiology of hypertension, Internal Medicine, Cardiology, Medicine, business, medicine.disease, Obesity
Published: 1999

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