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56,386 results on '"Cartwright, A."'

1. Dynamical equivalence between resonant translocation of a polymer chain and diversity-induced resonance

Author

Patriarca, Marco, Scialla, Stefano, Heinsalu, Els, Yamakou, Marius E., and Cartwright, Julyan H. E.

Subjects
Physics - Biological Physics
Abstract

Networks of heterogeneous oscillators are often seen to display collective synchronized oscillations, even when single elements of the network do not oscillate in isolation. It has been found that it is the diversity of the individual elements that drives the phenomenon, possibly leading to the appearance of a resonance in the response. Here we study the way in which heterogeneity acts in producing an oscillatory regime in a network and show that the resonance response is based on the same physics underlying the resonant translocation regime observed in models of polymer diffusion on a substrate potential. Such a mechanical analog provides an alternative viewpoint that is useful to interpret and understand the nature of collective oscillations in heterogeneous networks., Comment: 9 pages, 5 figures, 23 references

Published
2025

2. Quantum induced superradiance

Author

Cartwright, Casey, Gürsoy, Umut, Pedraza, Juan F., and Svesko, Andrew

Subjects
High Energy Physics - Theory, General Relativity and Quantum Cosmology
Abstract

Superradiance, the phenomenon enabling energy extraction through radiation amplification, is not universal to all black holes. We show that semi-classical backreaction can induce superradiance, even when absent at the classical level. Specifically, we compute the quasinormal modes of a massless scalar field probing a family of rotating `quantum' black holes in three-dimensional anti-de Sitter space, accounting for all orders of backreaction due to quantum conformal matter. A subset of these modes is identified as superradiant, leading to the formation of quantum black hole `bombs'. All such quantum black holes have curvature singularities shrouded by horizons. Thus, while backreaction enforces cosmic censorship, it also renders the black holes dynamically unstable. Further, we find all thermally unstable black holes are dynamically unstable, though the converse does not hold generally. Our findings thus suggest a semiclassical version of the Gubser-Mitra conjecture on black hole stability. This motivates us to propose a stability criterion for quantum black holes., Comment: Main document - 5 pages, 2 figures. Supplemental material - 7 pages, 4 figures. Mathematica notebook and data sets included. Comments welcome!

Published
2025

3. JWST Reveals Varied Origins Between Jupiter's Irregular Satellites

Author

Sharkey, Benjamin N. L., Rivkin, Andrew S., Cartwright, Richard J., Holler, Bryan J., Emery, Joshua P., and Thomas, Cristina

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

We report observations of eight Jovian irregular satellites with JWST's NIRSpec instrument: Himalia, Elara, Pasiphae, Sinope, Lysithea, Carme, Ananke, and Themisto. Irregular satellite families, which are presumed to have formed via collisions, contain various Trojan-like and C-type-asteroid-like surfaces. We sample the three largest members of the Himalia satellite family, detecting the presence of complexed CO$_2$ and a unique absorption band from $\sim2.7-3.6\ \mu m$ whose character correlates with satellite size. The two largest irregular satellites, Himalia family members Himalia and Elara, contain ammoniated phyllosilicates that are not seen in the meteorite inventory. We propose that the Himalia parent body was heterogeneous and formed with materials similar to Ceres-like ammonium-bearing asteroids. Several small ($D\sim 10km$) irregular satellites closely track the colors and absorption bands of ``red'' Jovian Trojans, demonstrating that these compositions are retained amongst the products of collisions that occurred after Jovian capture. We report the first detection of aqueous alteration products in the retrograde satellite swarm, finding Ananke's 3 micron band to closely match phyllosilicates seen in C2 chondrites. Notably, objects with OH absorption features similar to the Trojan asteroid Eurybates are found in both the retrograde Pasiphae family and the prograde Himalia family, confounding a simple link between such materials and a single surface type. The irregular satellites appear consistent with some materials that experienced alteration from liquid water and others that did not. Consequently, Jupiter may have captured bodies that formed from different initial compositions, or bodies that experienced different levels of heating, driving differential alteration processes., Comment: 20 Pages, 11 Figures, 2 Tables. Submitted to PSJ

Published
2025

4. Discovering Strong Gravitational Lenses in the Dark Energy Survey with Interactive Machine Learning and Crowd-sourced Inspection with Space Warps

Author

González, J., Holloway, P., Collett, T., Verma, A., Bechtol, K., Marshall, P., More, A., Barroso, J. Acevedo, Cartwright, G., Martinez, M., Li, T., Rojas, K., Schuldt, S., Birrer, S., Diehl, H. T., Morgan, R., Drlica-Wagner, A., O'Donnell, J. H., Zaborowski, E., Nord, B., Baeten, E. M., Johnson, L. C., Macmillan, C., Roodman, A., Pieres, A., Walker, A. R., Malagón, A. A. Plazas, Rosell, A. Carnero, Santiago, B., Flaugher, B., Gruen, D., Brooks, D., Burke, D. L., James, D. J., Cid, D. Sanchez, Hollowood, D. L., Tucker, D. L., Buckley-Geer, E., Gaztanaga, E., Suchyta, E., Sanchez, E., Gutierrez, G., Giannini, G., Tarle, G., Sevilla-Noarbe, I., Marshall, J. L., Carretero, J., Frieman, J., De Vicente, J., García-Bellido, J., Mena-Fernández, J., Myles, J., Honscheid, K., Kuehn, K., Lima, M., Pereira, M. E. S., Smith, M., Aguena, M., Weaverdyck, N., Lahav, O., Doel, P., Miquel, R., Gruendl, R. A., Cawthon, R., Hinton, S. R., Allam, S. S., Desai, S., Samuroff, S., Everett, S., Lee, S., Davis, T. M., Abbott, T. M. C., and Vikram, V.

Subjects
Astrophysics - Astrophysics of Galaxies
Abstract

We conduct a search for strong gravitational lenses in the Dark Energy Survey (DES) Year 6 imaging data. We implement a pre-trained Vision Transformer (ViT) for our machine learning (ML) architecture and adopt Interactive Machine Learning to construct a training sample with multiple classes to address common types of false positives. Our ML model reduces 236 million DES cutout images to 22,564 targets of interest, including around 85% of previously reported galaxy-galaxy lens candidates discovered in DES. These targets were visually inspected by citizen scientists, who ruled out approximately 90% as false positives. Of the remaining 2,618 candidates, 149 were expert-classified as 'definite' lenses and 516 as 'probable' lenses, with 147 of these candidates being newly identified. Additionally, we trained a second ViT to find double-source plane lens systems, finding at least one double-source system. Our main ViT excels at identifying galaxy-galaxy lenses, consistently assigning high scores to candidates with high confidence. The top 800 ViT-scored images include around 100 of our `definite' lens candidates. This selection is an order of magnitude higher in purity than previous convolutional neural network-based lens searches and demonstrates the feasibility of applying our methodology for discovering large samples of lenses in future surveys.

Published
2025

5. Humanity's Last Exam

Author

Phan, Long, Gatti, Alice, Han, Ziwen, Li, Nathaniel, Hu, Josephina, Zhang, Hugh, Zhang, Chen Bo Calvin, Shaaban, Mohamed, Ling, John, Shi, Sean, Choi, Michael, Agrawal, Anish, Chopra, Arnav, Khoja, Adam, Kim, Ryan, Ren, Richard, Hausenloy, Jason, Zhang, Oliver, Mazeika, Mantas, Nguyen, Tung, Anderson, Daron, Shah, Imad Ali, Doroshenko, Mikhail, Stokes, Alun Cennyth, Mahmood, Mobeen, Lee, Jaeho, Pokutnyi, Oleksandr, Iskra, Oleg, Wang, Jessica P., Gerbicz, Robert, Levin, John-Clark, Popov, Serguei, Feng, Fiona, Feng, Steven Y., Zhao, Haoran, Yu, Michael, Gangal, Varun, Zou, Chelsea, Wang, Zihan, Kazakov, Mstyslav, Galgon, Geoff, Schmitt, Johannes, Sanchez, Alvaro, Lee, Yongki, Yeadon, Will, Sauers, Scott, Roth, Marc, Agu, Chidozie, Riis, Søren, Giska, Fabian, Utpala, Saiteja, Cheatom, Antrell, Giboney, Zachary, Goshu, Gashaw M., Crowson, Sarah-Jane, Naiya, Mohinder Maheshbhai, Burns, Noah, Finke, Lennart, Cheng, Zerui, Park, Hyunwoo, Fournier-Facio, Francesco, Zampese, Jennifer, Wydallis, John B., Hoerr, Ryan G., Nandor, Mark, Gehrunger, Tim, Cai, Jiaqi, McCarty, Ben, Nam, Jungbae, Taylor, Edwin, Jin, Jun, Loume, Gautier Abou, Cao, Hangrui, Garretson, Alexis C, Sileo, Damien, Ren, Qiuyu, Cojoc, Doru, Arkhipov, Pavel, Qazi, Usman, Bacho, Aras, Li, Lianghui, Motwani, Sumeet, de Witt, Christian Schroeder, Kopylov, Alexei, Veith, Johannes, Singer, Eric, Rissone, Paolo, Jin, Jaehyeok, Shi, Jack Wei Lun, Willcocks, Chris G., Prabhu, Ameya, Tang, Longke, Zhou, Kevin, Santos, Emily de Oliveira, Maksimov, Andrey Pupasov, Vendrow, Edward, Zenitani, Kengo, Robinson, Joshua, Mikov, Aleksandar, Guillod, Julien, Li, Yuqi, Pageler, Ben, Vendrow, Joshua, Kuchkin, Vladyslav, Marion, Pierre, Efremov, Denis, Lynch, Jayson, Liang, Kaiqu, Gritsevskiy, Andrew, Martinez, Dakotah, Crispino, Nick, Zvonkine, Dimitri, Fraga, Natanael Wildner, Soori, Saeed, Press, Ori, Tang, Henry, Salazar, Julian, Green, Sean R., Brüssel, Lina, Twayana, Moon, Dieuleveut, Aymeric, Rogers, T. Ryan, Zhang, Wenjin, Finocchio, Ross, Li, Bikun, Yang, Jinzhou, Rao, Arun, Loiseau, Gabriel, Kalinin, Mikhail, Lukas, Marco, Manolescu, Ciprian, Stambaugh, Nate, Mishra, Subrata, Kamdoum, Ariel Ghislain Kemogne, Hogg, Tad, Jin, Alvin, Bosio, Carlo, Sun, Gongbo, Coppola, Brian P, Heidinger, Haline, Sayous, Rafael, Ivanov, Stefan, Cavanagh, Joseph M, Shen, Jiawei, Imperial, Joseph Marvin, Schwaller, Philippe, Senthilkuma, Shaipranesh, Bran, Andres M, Algaba, Andres, Verbeken, Brecht, Houte, Kelsey Van den, Van Der Sypt, Lynn, Noever, David, Schut, Lisa, Sucholutsky, Ilia, Zheltonozhskii, Evgenii, Yuan, Qiaochu, Lim, Derek, Stanley, Richard, Sivarajan, Shankar, Yang, Tong, Maar, John, Wykowski, Julian, Oller, Martí, Sandlin, Jennifer, Sahu, Anmol, Ardito, Cesare Giulio, Hu, Yuzheng, Dias, Felipe Meneguitti, Kreiman, Tobias, Rawal, Kaivalya, Vilchis, Tobias Garcia, Zu, Yuexuan, Lackner, Martin, Koppel, James, Nguyen, Jeremy, Antonenko, Daniil S., Chern, Steffi, Zhao, Bingchen, Arsene, Pierrot, Ivanov, Sergey, Poświata, Rafał, Wang, Chenguang, Li, Daofeng, Crisostomi, Donato, Dehghan, Ali, Achilleos, Andrea, Ambay, John Arnold, Myklebust, Benjamin, Sen, Archan, Perrella, David, Kaparov, Nurdin, Inlow, Mark H, Zang, Allen, Ramakrishnan, Kalyan, Orel, Daniil, Poritski, Vladislav, Ben-David, Shalev, Berger, Zachary, Whitfill, Parker, Foster, Michael, Munro, Daniel, Ho, Linh, Hava, Dan Bar, Kuchkin, Aleksey, Lauff, Robert, Holmes, David, Sommerhage, Frank, Zhang, Anji, Moat, Richard, Schneider, Keith, Pyda, Daniel, Kazibwe, Zakayo, Singh, Mukhwinder, Clarke, Don, Kim, Dae Hyun, Fish, Sara, Elser, Veit, Vilchis, Victor Efren Guadarrama, Klose, Immo, Demian, Christoph, Anantheswaran, Ujjwala, Zweiger, Adam, Albani, Guglielmo, Li, Jeffery, Daans, Nicolas, Radionov, Maksim, Rozhoň, Václav, Ginis, Vincent, Ma, Ziqiao, Stump, Christian, Platnick, Jacob, Nevirkovets, Volodymyr, Basler, Luke, Piccardo, Marco, Cohen, Niv, Singh, Virendra, Tkadlec, Josef, Rosu, Paul, Goldfarb, Alan, Padlewski, Piotr, Barzowski, Stanislaw, Montgomery, Kyle, Menezes, Aline, Patel, Arkil, Wang, Zixuan, Tucker-Foltz, Jamie, Stade, Jack, Grabb, Declan, Goertzen, Tom, Kazemi, Fereshteh, Milbauer, Jeremiah, Shukla, Abhishek, Elgnainy, Hossam, Labrador, Yan Carlos Leyva, He, Hao, Zhang, Ling, Givré, Alan, Wolff, Hew, Demir, Gözdenur, Aziz, Muhammad Fayez, Kaddar, Younesse, Ängquist, Ivar, Chen, Yanxu, Thornley, Elliott, Zhang, Robin, Pan, Jiayi, Terpin, Antonio, Muennighoff, Niklas, Schoelkopf, Hailey, Zheng, Eric, Carmi, Avishy, Shah, Jainam, Brown, Ethan D. L., Zhu, Kelin, Bartolo, Max, Wheeler, Richard, Ho, Andrew, Barkan, Shaul, Wang, Jiaqi, Stehberger, Martin, Kretov, Egor, Bradshaw, Peter, Heimonen, JP, Sridhar, Kaustubh, Hossain, Zaki, Akov, Ido, Makarychev, Yury, Tam, Joanna, Hoang, Hieu, Cunningham, David M., Goryachev, Vladimir, Patramanis, Demosthenes, Krause, Michael, Redenti, Andrew, Aldous, David, Lai, Jesyin, Coleman, Shannon, Xu, Jiangnan, Lee, Sangwon, Magoulas, Ilias, Zhao, Sandy, Tang, Ning, Cohen, Michael K., Carroll, Micah, Paradise, Orr, Kirchner, Jan Hendrik, Steinerberger, Stefan, Ovchynnikov, Maksym, Matos, Jason O., Shenoy, Adithya, Wang, Michael, Nie, Yuzhou, Giordano, Paolo, Petersen, Philipp, Sztyber-Betley, Anna, Faraboschi, Paolo, Riblet, Robin, Crozier, Jonathan, Halasyamani, Shiv, Pinto, Antonella, Verma, Shreyas, Joshi, Prashant, Meril, Eli, Yong, Zheng-Xin, Tee, Allison, Andréoletti, Jérémy, Weller, Orion, Singhal, Raghav, Zhang, Gang, Ivanov, Alexander, Khoury, Seri, Gustafsson, Nils, Mostaghimi, Hamid, Thaman, Kunvar, Chen, Qijia, Khánh, Tran Quoc, Loader, Jacob, Cavalleri, Stefano, Szlyk, Hannah, Brown, Zachary, Narayan, Himanshu, Roberts, Jonathan, Alley, William, Sun, Kunyang, Stendall, Ryan, Lamparth, Max, Reuel, Anka, Wang, Ting, Xu, Hanmeng, Hernández-Cámara, Pablo, Martin, Freddie, Preu, Thomas, Korbak, Tomek, Abramovitch, Marcus, Williamson, Dominic, Bosio, Ida, Chen, Ziye, Bálint, Biró, Lo, Eve J. Y., Nunes, Maria Inês S., Jiang, Yibo, Bari, M Saiful, Kassani, Peyman, Wang, Zihao, Ansarinejad, Behzad, Sun, Yewen, Durand, Stephane, Douville, Guillaume, Tordera, Daniel, Balabanian, George, Anderson, Earth, Kvistad, Lynna, Moyano, Alejandro José, Milliron, Hsiaoyun, Sakor, Ahmad, Eron, Murat, McAlister, Isaac C., O., Andrew Favre D., Shah, Shailesh, Zhou, Xiaoxiang, Kamalov, Firuz, Clark, Ronald, Abdoli, Sherwin, Santens, Tim, Wang, Harrison K, Chen, Evan, Tomasiello, Alessandro, De Luca, G. Bruno, Looi, Shi-Zhuo, Le, Vinh-Kha, Kolt, Noam, Mündler, Niels, Semler, Avi, Rodman, Emma, Drori, Jacob, Fossum, Carl J, Gloor, Luk, Jagota, Milind, Pradeep, Ronak, Fan, Honglu, Shah, Tej, Eicher, Jonathan, Chen, Michael, Thaman, Kushal, Merrill, William, Firsching, Moritz, Harris, Carter, Ciobâcă, Stefan, Gross, Jason, Pandey, Rohan, Gusev, Ilya, Jones, Adam, Agnihotri, Shashank, Zhelnov, Pavel, Usawasutsakorn, Siranut, Mofayezi, Mohammadreza, Piperski, Alexander, Carauleanu, Marc, Zhang, David K., Dobarskyi, Kostiantyn, Ler, Dylan, Leventov, Roman, Soroko, Ignat, Jansen, Thorben, Creighton, Scott, Lauer, Pascal, Duersch, Joshua, Taamazyan, Vage, Bezzi, Dario, Morak, Wiktor, Ma, Wenjie, Held, William, Huy, Tran Đuc, Xian, Ruicheng, Zebaze, Armel Randy, Mohamed, Mohanad, Leser, Julian Noah, Yuan, Michelle X, Yacar, Laila, Lengler, Johannes, Olszewska, Katarzyna, Shahrtash, Hossein, Oliveira, Edson, Jackson, Joseph W., Gonzalez, Daniel Espinosa, Zou, Andy, Chidambaram, Muthu, Manik, Timothy, Haffenden, Hector, Stander, Dashiell, Dasouqi, Ali, Shen, Alexander, Duc, Emilien, Golshani, Bita, Stap, David, Uzhou, Mikalai, Zhidkovskaya, Alina Borisovna, Lewark, Lukas, Rodriguez, Miguel Orbegozo, Vincze, Mátyás, Wehr, Dustin, Tang, Colin, Phillips, Shaun, Samuele, Fortuna, Muzhen, Jiang, Ekström, Fredrik, Hammon, Angela, Patel, Oam, Farhidi, Faraz, Medley, George, Mohammadzadeh, Forough, Peñaflor, Madellene, Kassahun, Haile, Friedrich, Alena, Sparrow, Claire, Perez, Rayner Hernandez, Sakal, Taom, Dhamane, Omkar, Mirabadi, Ali Khajegili, Hallman, Eric, Okutsu, Kenchi, Battaglia, Mike, Maghsoudimehrabani, Mohammad, Amit, Alon, Hulbert, Dave, Pereira, Roberto, Weber, Simon, Handoko, Peristyy, Anton, Malina, Stephen, Albanie, Samuel, Cai, Will, Mehkary, Mustafa, Aly, Rami, Reidegeld, Frank, Dick, Anna-Katharina, Friday, Cary, Sidhu, Jasdeep, Shapourian, Hassan, Kim, Wanyoung, Costa, Mariana, Gurdogan, Hubeyb, Weber, Brian, Kumar, Harsh, Jiang, Tong, Agarwal, Arunim, Ceconello, Chiara, Vaz, Warren S., Zhuang, Chao, Park, Haon, Tawfeek, Andrew R., Aggarwal, Daattavya, Kirchhof, Michael, Dai, Linjie, Kim, Evan, Ferret, Johan, Wang, Yuzhou, Yan, Minghao, Burdzy, Krzysztof, Zhang, Lixin, Franca, Antonio, Pham, Diana T., Loh, Kang Yong, Jackson, Abram, Gul, Shreen, Chhablani, Gunjan, Du, Zhehang, Cosma, Adrian, Colino, Jesus, White, Colin, Votava, Jacob, Vinnikov, Vladimir, Delaney, Ethan, Spelda, Petr, Stritecky, Vit, Shahid, Syed M., Mourrat, Jean-Christophe, Vetoshkin, Lavr, Sponselee, Koen, Bacho, Renas, de la Rosa, Florencia, Li, Xiuyu, Malod, Guillaume, Lang, Leon, Laurendeau, Julien, Kazakov, Dmitry, Adesanya, Fatimah, Portier, Julien, Hollom, Lawrence, Souza, Victor, Zhou, Yuchen Anna, Degorre, Julien, Yalın, Yiğit, Obikoya, Gbenga Daniel, Arnaboldi, Luca, Rai, Bigi, Filippo, Boscá, M. C., Shumar, Oleg, Bacho, Kaniuar, Clavier, Pierre, Recchia, Gabriel, Popescu, Mara, Shulga, Nikita, Tanwie, Ngefor Mildred, Peskoff, Denis, Lux, Thomas C. H., Rank, Ben, Ni, Colin, Brooks, Matthew, Yakimchyk, Alesia, Huanxu, Liu, Häggström, Olle, Verkama, Emil, Gundlach, Hans, Brito-Santana, Leonor, Amaro, Brian, Vajipey, Vivek, Grover, Rynaa, Fan, Yiyang, Silva, Gabriel Poesia Reis e, Xin, Linwei, Kratish, Yosi, Łucki, Jakub, Li, Wen-Ding, Gopi, Sivakanth, Caciolai, Andrea, Xu, Justin, Scaria, Kevin Joseph, Vargus, Freddie, Habibi, Farzad, Long, Lian, Rodolà, Emanuele, Robins, Jules, Cheng, Vincent, Fruhauff, Tony, Raynor, Brad, Qi, Hao, Jiang, Xi, Segev, Ben, Fan, Jingxuan, Martinson, Sarah, Wang, Erik Y., Hausknecht, Kaylie, Brenner, Michael P., Mao, Mao, Zhang, Xinyu, Avagian, David, Scipio, Eshawn Jessica, Ragoler, Alon, Tan, Justin, Sims, Blake, Plecnik, Rebeka, Kirtland, Aaron, Bodur, Omer Faruk, Shinde, D. P., Adoul, Zahra, Zekry, Mohamed, Karakoc, Ali, Santos, Tania C. B., Shamseldeen, Samir, Karim, Loukmane, Liakhovitskaia, Anna, Resman, Nate, Farina, Nicholas, Gonzalez, Juan Carlos, Maayan, Gabe, Hoback, Sarah, Pena, Rodrigo De Oliveira, Sherman, Glen, Kelley, Elizabeth, Mariji, Hodjat, Pouriamanesh, Rasoul, Wu, Wentao, Mendoza, Sandra, Alarab, Ismail, Cole, Joshua, Ferreira, Danyelle, Johnson, Bryan, Safdari, Mohammad, Dai, Liangti, Arthornthurasuk, Siriphan, Pronin, Alexey, Fan, Jing, Ramirez-Trinidad, Angel, Cartwright, Ashley, Pottmaier, Daphiny, Taheri, Omid, Outevsky, David, Stepanic, Stanley, Perry, Samuel, Askew, Luke, Rodríguez, Raúl Adrián Huerta, Minissi, Ali M. R., Ali, Sam, Lorena, Ricardo, Iyer, Krishnamurthy, Fasiludeen, Arshad Anil, Salauddin, Sk Md, Islam, Murat, Gonzalez, Juan, Ducey, Josh, Somrak, Maja, Mavroudis, Vasilios, Vergo, Eric, Qin, Juehang, Borbás, Benjámin, Chu, Eric, Lindsey, Jack, Radhakrishnan, Anil, Jallon, Antoine, McInnis, I. M. J., Kumar, Pawan, Goswami, Laxman Prasad, Bugas, Daniel, Heydari, Nasser, Jeanplong, Ferenc, Apronti, Archimedes, Galal, Abdallah, Ze-An, Ng, Singh, Ankit, Xavier, Joan of Arc, Agarwal, Kanu Priya, Berkani, Mohammed, Junior, Benedito Alves de Oliveira, Malishev, Dmitry, Remy, Nicolas, Hartman, Taylor D., Tarver, Tim, Mensah, Stephen, Gimenez, Javier, Montecillo, Roselynn Grace, Campbell, Russell, Sharma, Asankhaya, Meer, Khalida, Alapont, Xavier, Patil, Deepakkumar, Maheshwari, Rajat, Dendane, Abdelkader, Shukla, Priti, Bogdanov, Sergei, Möller, Sören, Siddiqi, Muhammad Rehan, Saxena, Prajvi, Gupta, Himanshu, Enyekwe, Innocent, P V, Ragavendran, EL-Wasif, Zienab, Maksapetyan, Aleksandr, Rossbach, Vivien, Harjadi, Chris, Bahaloohoreh, Mohsen, Bian, Song, Lai, John, Uro, Justine Leon, Bateman, Greg, Sayed, Mohamed, Menshawy, Ahmed, Duclosel, Darling, Jain, Yashaswini, Aaron, Ashley, Tiryakioglu, Murat, Siddh, Sheeshram, Krenek, Keith, Hoover, Alex, McGowan, Joseph, Patwardhan, Tejal, Yue, Summer, Wang, Alexandr, and Hendrycks, Dan

Subjects
Computer Science - Machine Learning, Computer Science - Artificial Intelligence, Computer Science - Computation and Language
Abstract

Benchmarks are important tools for tracking the rapid advancements in large language model (LLM) capabilities. However, benchmarks are not keeping pace in difficulty: LLMs now achieve over 90\% accuracy on popular benchmarks like MMLU, limiting informed measurement of state-of-the-art LLM capabilities. In response, we introduce Humanity's Last Exam (HLE), a multi-modal benchmark at the frontier of human knowledge, designed to be the final closed-ended academic benchmark of its kind with broad subject coverage. HLE consists of 2,700 questions across dozens of subjects, including mathematics, humanities, and the natural sciences. HLE is developed globally by subject-matter experts and consists of multiple-choice and short-answer questions suitable for automated grading. Each question has a known solution that is unambiguous and easily verifiable, but cannot be quickly answered via internet retrieval. State-of-the-art LLMs demonstrate low accuracy and calibration on HLE, highlighting a significant gap between current LLM capabilities and the expert human frontier on closed-ended academic questions. To inform research and policymaking upon a clear understanding of model capabilities, we publicly release HLE at https://lastexam.ai., Comment: 27 pages, 6 figures

Published
2025

6. Self-Organized Pattern Formation in Geological Soft Matter

Author

Cartwright, Julyan H. E., Cockell, Charles S., Goehring, Lucas, Holler, Silvia, Jordan, Sean F., Knoll, Pamela, Kotopoulou, Electra, Loron, Corentin C., McMahon, Sean, Morris, Stephen W., Neubeck, Anna, Pimentel, Carlos, Sainz-Díaz, C. Ignacio, Shahidzadeh, Noushine, and Szymczak, Piotr

Subjects
Physics - Geophysics, Condensed Matter - Soft Condensed Matter, Nonlinear Sciences - Adaptation and Self-Organizing Systems
Abstract

Geological materials are often seen as the antithesis of soft; rocks are hard. However, during the formation of minerals and rocks, all the systems we shall discuss, indeed geological materials in general, pass through a stage where they are soft. This occurs either because they are at a high temperature -- igneous or metamorphic rock -- or because they are at a lower temperature but in the presence of water -- sedimentary rock. For this reason it is useful to introduce soft-matter concepts into the geological domain. There is a universality in the diverse instances of geological patterns that may be appreciated by looking at the common aspect in their formation of having passed through a stage as soft matter.

Published
2024

7. Strongly interacting matter in extreme magnetic fields

Author

Adhikari, Prabal, Ammon, Martin, Avancini, Sidney S., Ayala, Alejandro, Bandyopadhyay, Aritra, Blaschke, David, Braghin, Fabio L., Buividovich, Pavel, Cardoso, Rafael P., Cartwright, Casey, Castaño-Yepes, Jorge David, Chernodub, Maxim, Coppola, M., Das, Mayusree, Dutra, Mariana, Endrődi, Gergely, Fang, Jianjun, Farias, Ricardo L. S., Fraga, Eduardo S., Frazon, Arthur, Fukushima, Kenji, García-Muñoz, Juan D., Garnacho-Velasco, Eduardo, Dumm, D. Gomez, Grieninger, Sebastian, Gulminelli, Francesca, Hernandez, Juan, Islam, Chowdhury Aminul, Kaminski, Matthias, Kotov, Andrey, Krein, Gastão, Li, Jing, Lo, Pok Man, Loewe, Marcelo, Lourenço, Odilon, Markó, Gergely, Marquez, Kau D., Mizher, Ana, Mukhopadhyay, Banibrata, Muñoz, Enrique, Noguera, S., Nunes, Rodrigo M., Pais, Helena, Palhares, Letícia F., Providência, Constança, Raya, Alfredo, Restrepo, Tulio, Rojas, Juan Cristóbal, Scoccola, N. N., Scurto, Luigi, Sedrakian, Armen, Smith, Dominik, Tavares, William Rafael, Tejeda-Yeomans, Maria E., Timóteo, Varese S., Tolos, Laura, Villavicencio, Cristian, Weber, Fridolin, Yasui, Shigehiro, Zamora, Renato, and Zuraiq, Zenia

Subjects
Nuclear Theory
Abstract

Magnetic fields are ubiquitous across different physical systems of current interest; from the early Universe, compact astrophysical objects and heavy-ion collisions to condensed matter systems. A proper treatment of the effects produced by magnetic fields during the dynamical evolution of these systems, can help to understand observables that otherwise show a puzzling behavior. Furthermore, when these fields are comparable to or stronger than \Lambda_QCD, they serve as excellent probes to help elucidate the physics of strongly interacting matter under extreme conditions of temperature and density. In this work we provide a comprehensive review of recent developments on the description of QED and QCD systems where magnetic field driven effects are important. These include the modification of meson static properties such as masses and form factors, the chiral magnetic effect, the description of anomalous transport coefficients, superconductivity in extreme magnetic fields, the properties of neutron stars, the evolution of heavy-ion collisions, as well as effects on the QCD phase diagram. We describe recent theory and phenomenological developments using effective models as well as LQCD methods. The work represents a state-of-the-art review of the field, motivated by presentations and discussions during the "Workshop on Strongly Interacting Matter in Strong Electromagnetic Fields" that took place in the European Centre for Theoretical Studies in Nuclear Physics and Related Areas (ECT*) in the city of Trento, Italy, September 25-29, 2023., Comment: 325 pages-long review of recent topics of interest in the field of magnetic field effects on QED and QCD matter. To be susbmitted to PNPP

Published
2024

8. Splitting the atom before the atom had been split

Author

Cartwright, Julyan H. E.

Subjects
Physics - History and Philosophy of Physics, Nuclear Experiment
Abstract

The history of the discovery of nuclear fission and how science fiction had anticipated it.

Published
2024

9. EmotionCaps: Enhancing Audio Captioning Through Emotion-Augmented Data Generation

Author

Manivannan, Mithun, Nethrapalli, Vignesh, and Cartwright, Mark

Subjects
Computer Science - Sound, Computer Science - Machine Learning, Electrical Engineering and Systems Science - Audio and Speech Processing, Electrical Engineering and Systems Science - Signal Processing
Abstract

Recent progress in audio-language modeling, such as automated audio captioning, has benefited from training on synthetic data generated with the aid of large-language models. However, such approaches for environmental sound captioning have primarily focused on audio event tags and have not explored leveraging emotional information that may be present in recordings. In this work, we explore the benefit of generating emotion-augmented synthetic audio caption data by instructing ChatGPT with additional acoustic information in the form of estimated soundscape emotion. To do so, we introduce EmotionCaps, an audio captioning dataset comprised of approximately 120,000 audio clips with paired synthetic descriptions enriched with soundscape emotion recognition (SER) information. We hypothesize that this additional information will result in higher-quality captions that match the emotional tone of the audio recording, which will, in turn, improve the performance of captioning models trained with this data. We test this hypothesis through both objective and subjective evaluation, comparing models trained with the EmotionCaps dataset to multiple baseline models. Our findings challenge current approaches to captioning and suggest new directions for developing and assessing captioning models.

Published
2024

10. Strategies to Build the Vocabulary and Background Knowledge of Students with Learning Disabilities

Author

Zachary T. Barnes and Kelly B. Cartwright

Abstract

Comprehending texts in content areas can be challenging for students with learning disabilities (LD) because they may lack the necessary background and vocabulary knowledge needed to construct meaning from text. As more students with LD are educated in the general education classroom, it is necessary for teachers to implement strategies to increase the vocabulary and background knowledge of their students. The purpose of this paper is to provide effective instructional strategies to build both background knowledge and vocabulary knowledge to increase comprehension of content area material.

Published
2024
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11. A patchy CO$_2$ exosphere on Ganymede revealed by the James Webb Space Telescope

Author

Bockelée-Morvan, Dominique, Poch, Olivier, Leblanc, Françcois, Zakharov, Vladimir, Lellouch, Emmanuel, Quirico, Eric, de Pater, Imke, Fouchet, Thierry, Rodriguez-Ovalle, Pablo, Roth, Lorenz, Merlin, Frédéric, Duling, Stefan, Saur, Joachim, Masson, Adrien, Fry, Patrick, Trumbo, Samantha, Brown, Michael, Cartwright, Richard, Cazaux, Stéphanie, de Kleer, Katherine, Fletcher, Leigh N., Milby, Zachariah, Moingeon, Audrey, Mura, Alessandro, Orton, Glenn S., Schmitt, Bernard, Tosi, Federico, and Wong, Michael H.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

Jupiter's icy moon Ganymede has a tenuous exosphere produced by sputtering and possibly sublimation of water ice. To date, only atomic hydrogen and oxygen have been directly detected in this exosphere. Here, we present observations of Ganymede's CO$_2$ exosphere obtained with the James Webb Space Telescope. CO$_2$ gas is observed over different terrain types, mainly over those exposed to intense Jovian plasma irradiation, as well as over some bright or dark terrains. Despite warm surface temperatures, the CO$_2$ abundance over equatorial subsolar regions is low. CO$_2$ vapor has the highest abundance over the north polar cap of the leading hemisphere, reaching a surface pressure of 1 pbar. From modeling we show that the local enhancement observed near 12 h local time in this region can be explained by the presence of cold traps enabling CO$_2$ adsorption. However, whether the release mechanism in this high-latitude region is sputtering or sublimation remains unclear. The north polar cap of the leading hemisphere also has unique surface-ice properties, probably linked to the presence of the large atmospheric CO2 excess over this region. These CO2 molecules might have been initially released in the atmosphere after the radiolysis of CO$_2$ precursors, or from the sputtering of CO$_2$ embedded in the H$_2$O ice bedrock. Dark terrains (regiones), more widespread on the north versus south polar regions, possibly harbor CO$_2$ precursors. CO$_2$ molecules would then be redistributed via cold trapping on ice-rich terrains of the polar cap and be diurnally released and redeposited on these terrains. Ganymede's CO$_2$ exosphere highlights the complexity of surface-atmosphere interactions on Jupiter's icy Galilean moons., Comment: 21 pages, 21 figures, Accepted as a Letter in Astronomy and Astrophysics

Published
2024
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12. Compositional Audio Representation Learning

Author

Sridhar, Sripathi and Cartwright, Mark

Subjects
Computer Science - Sound, Electrical Engineering and Systems Science - Audio and Speech Processing
Abstract

Human auditory perception is compositional in nature -- we identify auditory streams from auditory scenes with multiple sound events. However, such auditory scenes are typically represented using clip-level representations that do not disentangle the constituent sound sources. In this work, we learn source-centric audio representations where each sound source is represented using a distinct, disentangled source embedding in the audio representation. We propose two novel approaches to learning source-centric audio representations: a supervised model guided by classification and an unsupervised model guided by feature reconstruction, both of which outperform the baselines. We thoroughly evaluate the design choices of both approaches using an audio classification task. We find that supervision is beneficial to learn source-centric representations, and that reconstructing audio features is more useful than reconstructing spectrograms to learn unsupervised source-centric representations. Leveraging source-centric models can help unlock the potential of greater interpretability and more flexible decoding in machine listening., Comment: Accepted to ICASSP 2025

Published
2024

13. Perturbing a quantum black hole

Author

Cartwright, Casey, Gürsoy, Umut, Pedraza, Juan F., and Planas, Guim Planella

Subjects
High Energy Physics - Theory, General Relativity and Quantum Cosmology
Abstract

We analyze the analytic structure of correlators in the field theory dual to the quantum Ba\~{n}ados-Teitelboim-Zanelli (qBTZ) black hole, a braneworld model incorporating exact backreaction from quantum conformal matter. We first compute the quasi-normal mode (QNM) spectrum of operators with dimension $\Delta$ and spin $s=0,\pm 1/2$. The leading QNMs and their overtones display qualitatively different behavior depending on the branch of qBTZ solution; branch 1 is a conical singularity dressed with a horizon while branch 2 is a quantum-corrected BTZ black hole. Hence the relaxation of probe matter distinguishes the type of singularity cloaked by the horizon. We then turn to pole-skipping locations where Green's functions are not unique. At these points, frequency is proportional to temperature, but momentum exhibits complex temperature dependence due to quantum effects. Under the assumption that the pole-skipping point closest to the origin reflects quantum chaos, we infer the likely behavior of the quantum Lyapunov exponent and butterfly velocity in the dual theory. Finally, we examine pole collisions in complex momentum space, showing that quantum corrections imprint a unique signature on the analytic structure of the poles in retarded Green's functions, resulting in level-crossing phenomena that differ notably from the level-touching phenomena in the uncorrected BTZ geometry., Comment: 70 pages, 27 figures. comments welcome!

Published
2024

14. A supersymmetric spin current

Author

Cartwright, Casey, Gallegos, Domingo, Gürsoy, Umut, Klein, Roi, and Yarom, Amos

Subjects
High Energy Physics - Theory, General Relativity and Quantum Cosmology
Abstract

We study the supersymmetric structure of the spin current in four dimensional $\mathcal{N}=1$ supersymmetric theories. By coupling the stress tensor multiplet to a vierbein multiplet we identify a spin current with the Hodge dual of the bottom component of the stress tensor multiplet in a wide range of theories. This implies that in holographic theories the Hodge dual of the $R$ current may serve as a spin current, paving the way for holographic studies of theories with background torsion.

Published
2024

18. A synchrotron-like pumped ring resonator for water waves

Author

Vivanco, Isis, Egli, Alexander, Cartwright, Bruce, Marín, Juan F., and Gordillo, Leonardo

Subjects
Physics - Fluid Dynamics
Abstract

The wave-like behaviour of matter in quantum physics has spurred insightful analogies between the dynamics of particles and waves in classical systems. In this study, drawing inspiration from synchrotrons that resonate to accelerate ions along a closed path, we introduce the concept of a synchrowave: a waveguide designed to generate and sustain travelling water waves within a closed annular channel. In analogy to unavoidable energy losses in conventional particle accelerators due to electromagnetic radiation and inelastic collisions, the system displays undesired water-wave dampening, which we address through the synchronised action of underwater wavemakers. Our analogies extend the resonance mechanisms of synchrotrons to generate gravity waves in closed waveguides efficiently. A proof-of-concept experiment at a laboratory scale demonstrates the unique capability of this technique to build up anomalously large travelling waves displaying a flat response in the long-wave limit. Besides quantifying the performance of wave generation, our findings offer a framework for both industrial and computational applications, opening up unexplored possibilities in hydraulics, coastal science and engineering. In a broader context, our experimental apparatus and methods highlight the versatility of a simple yet powerful concept: a closed-path continuous-energy-pumping scheme to effectively harvest prominent resonant responses within wave-supporting systems displaying weak dissipation., Comment: 7 figures

Published
2024

19. First joint oscillation analysis of Super-Kamiokande atmospheric and T2K accelerator neutrino data

Author

Super-Kamiokande, collaborations, T2K, Abe, S., Abe, K., Akhlaq, N., Akutsu, R., Alarakia-Charles, H., Ali, A., Hakim, Y. I. Alj, Monsalve, S. Alonso, Amanai, S., Andreopoulos, C., Anthony, L. H. V., Antonova, M., Aoki, S., Apte, K. A., Arai, T., Arihara, T., Arimoto, S., Asada, Y., Asaka, R., Ashida, Y., Atkin, E. T., Babu, N., Barbi, M., Barker, G. J., Barr, G., Barrow, D., Bates, P., Batkiewicz-Kwasniak, M., Beauchêne, A., Berardi, V., Berns, L., Bhadra, S., Bhuiyan, N., Bian, J., Blanchet, A., Blondel, A., Bodur, B., Bolognesi, S., Bordoni, S., Boyd, S. B., Bravar, A., Bronner, C., Bubak, A., Avanzini, M. Buizza, Burton, G. T., Caballero, J. A., Calabria, N. F., Cao, S., Carabadjac, D., Carter, A. J., Cartwright, S. L., Casado, M. P., Catanesi, M. G., Cervera, A., Chakrani, J., Chalumeau, A., Chen, S., Cherdack, D., Choi, K., Chong, P. S., Chvirova, A., Cicerchia, M., Coleman, J., Collazuol, G., Cook, L., Cormier, F., Cudd, A., Dalmazzone, C., Daret, T., Dasgupta, P., Davis, C., Davydov, Yu. I., De Roeck, A., De Rosa, G., Dealtry, T., Delogu, C. C., Densham, C., Dergacheva, A., Dharmapal, R., Di Lodovico, F., Lopez, G. Diaz, Dolan, S., Douqa, D., Doyle, T. A., Drapier, O., Duffy, K. E., Dumarchez, J., Dunne, P., Dygnarowicz, K., D'ago, D., Edwards, R., Eguchi, A., Elias, J., Emery-Schrenk, S., Erofeev, G., Ershova, A., Eurin, G., Fannon, J. E. P., Fedorova, D., Fedotov, S., Feltre, M., Feng, J., Feng, L., Ferlewicz, D., Fernandez, P., Finch, A. J., Aguirre, G. A. Fiorentini, Fiorillo, G., Fitton, M. D., Patiño, J. M. Franco, Friend, M., Fujii, Y., Fujisawa, C., Fujita, S., Fukuda, Y., Furui, Y., Gao, J., Gaur, R., Giampaolo, A., Giannessi, L., Giganti, C., Glagolev, V., Goldsack, A., Gonin, M., Rosa, J. González, Goodman, E. A. G., Gorin, A., Gorshanov, K., Gousy-Leblanc, V., Grassi, M., Griskevich, N. J., Guigue, M., Hadley, D., Haigh, J. T., Han, S., Harada, M., Harris, D. A., Hartz, M., Hasegawa, T., Hassani, S., Hastings, N. C., Hayato, Y., Heitkamp, I., Henaff, D., Hill, J., Hino, Y., Hiraide, K., Hogan, M., Holeczek, J., Holin, A., Holvey, T., Van, N. T. Hong, Honjo, T., Horiuchi, S., Hosokawa, K., Hu, Z., Hu, J., Iacob, F., Ichikawa, A. K., Ieki, K., Ikeda, M., Iovine, N., Ishida, T., Ishino, H., Ishitsuka, M., Ishizuka, T., Ito, H., Itow, Y., Izmaylov, A., Izumiyama, S., Jakkapu, M., Jamieson, B., Jang, M. C., Jang, J. S., Jenkins, S. J., Jesús-Valls, C., Ji, J. Y., Jia, M., Jiang, J., Jonsson, P., Joshi, S., Jung, C. K., Jung, S., Kabirnezhad, M., Kaboth, A. C., Kajita, T., Kakuno, H., Kameda, J., Kanemura, Y., Kaneshima, R., Karpova, S., Kasetti, S. P., Kashiwagi, Y., Kasturi, V. S., Kataoka, Y., Katori, T., Kawamura, Y., Kawaue, M., Kearns, E., Khabibullin, M., Khotjantsev, A., Kikawa, T., Kim, S. B., King, S., Kiseeva, V., Kisiel, J., Kneale, L., Kobayashi, H., Kobayashi, T., Kobayashi, M., Koch, L., Kodama, S., Kolupanova, M., Konaka, A., Kormos, L. L., Koshio, Y., Koto, T., Kowalik, K., Kudenko, Y., Kudo, Y., Kuribayashi, S., Kurjata, R., Kurochka, V., Kutter, T., Kuze, M., Kwon, E., La Commara, M., Labarga, L., Lachat, M., Lachner, K., Lagoda, J., Lakshmi, S. M., LamersJames, M., Langella, A., Laporte, J. -F., Last, D., Latham, N., Laveder, M., Lavitola, L., Lawe, M., Learned, J. G., Lee, Y., Lee, S. H., Silverio, D. Leon, Levorato, S., Lewis, S., Li, X., Li, W., Lin, C., Litchfield, R. P., Liu, S. L., Liu, Y. M., Long, K. R., Longhin, A., Moreno, A. Lopez, Lu, X., Ludovici, L., Lux, T., Machado, L. N., Maekawa, Y., Magaletti, L., Mahn, K., Mahtani, K. K., Malek, M., Mandal, M., Manly, S., Marino, A. D., Martens, K., Marti, Ll., Martin, D. G. R., Martin, J. F., Martin, D., Martini, M., Maruyama, T., Matsubara, T., Matsumoto, R., Mattiazzi, M., Matveev, V., Mauger, C., Mavrokoridis, K., Mazzucato, E., McCauley, N., McElwee, J. M., McFarland, K. S., McGrew, C., McKean, J., Mefodiev, A., Megias, G. D., Mehta, P., Mellet, L., Menjo, H., Metelko, C., Mezzetto, M., Migenda, J., Mijakowski, P., Miki, S., Miller, E., Minamino, A., Mine, S., Mineev, O., Mirabito, J., Miura, M., Bueno, L. Molina, Moon, D. H., Mori, M., Moriyama, S., Morrison, P., Muñoz, A., Mueller, Th. A., Munford, D., Munteanu, L., Nagai, Y., Nagai, K., Nakadaira, T., Nakagiri, K., Nakahata, M., Nakajima, Y., Nakamura, A., Nakamura, K., Nakamura, K. D., Nakamura, T., Nakanishi, F., Nakano, Y., Nakaya, T., Nakayama, S., Nakayoshi, K., Naseby, C. E. R., Ngoc, T. V., Nguyen, V. Q., Nguyen, D. T., Nicholson, M., Niewczas, K., Ninomiya, K., Nishijima, K., Nishimori, S., Nishimura, Y., Noguchi, Y., Nosek, T., Nova, F., Novella, P., Nugent, J. C., Odagawa, T., Okazaki, R., Okazawa, H., Okinaga, W., Okumura, K., Okusawa, T., Ommura, Y., Onda, N., Ospina, N., Osu, L., Oyama, Y., O'Flaherty, M., O'Keeffe, H. M., O'Sullivan, L., Périssé, L., Paganini, P., Palladino, V., Paolone, V., Pari, M., Park, R. G., Parlone, J., Pasternak, J., Payne, D., Penn, G. C., de Perio, P., Pershey, D., Pfaff, M., Pickering, L., Pintaudi, G., Pistillo, C., Pointon, B. W., Popov, B., Yrey, A. Portocarrero, Porwit, K., Posiadala-Zezula, M., Prabhu, Y. S., Prasad, H., Pronost, G., Prouse, N. W., Pupilli, F., Quilain, B., Quyen, P. T., Raaf, J. L., Radermacher, T., Radicioni, E., Radics, B., Ramirez, M. A., Ramsden, R. M., Ratoff, P. N., Reh, M., Riccio, C., Richards, B., Rogly, R., Rondio, E., Roth, S., Roy, N., Rubbia, A., Russo, L., Rychter, A., Saenz, W., Sakai, S., Sakashita, K., Samani, S., Santos, A. D., Sato, Y., Sato, K., Schefke, T., Schloesser, C. M., Scholberg, K., Scott, M., Seiya, Y., Sekiguchi, T., Sekiya, H., Seo, J. W., Sgalaberna, D., Shaikhiev, A., Shi, W., Shiba, H., Shibayama, R., Shigeta, N., Shima, S., Shimamura, R., Shimizu, K., Shinoki, M., Shiozawa, M., Shiraishi, Y., Shvartsman, A., Skrobova, N., Skwarczynski, K., Smy, M. B., Smyczek, D., Sobczyk, J. T., Sobel, H. W., Soler, F. J. P., Sonoda, Y., Speers, A. J., Spina, R., Stroke, Y., Suslov, I. A., Suvorov, S., Suzuki, S., Suzuki, A., Suzuki, S. Y., Suzuki, Y., Sánchez, F., Tada, T., Tada, M., Tairafune, S., Takagi, Y., Takeda, A., Takemoto, Y., Takeuchi, Y., Takhistov, V., Takifuji, K., Tanaka, H., Tanaka, H. K., Tanigawa, H., Taniuchi, N., Tano, T., Tarrant, A., Tashiro, T., Teklu, A., Terada, K., Tereshchenko, V. V., Thamm, N., Thiesse, M. D., Thompson, L. F., Toki, W., Tomiya, T., Touramanis, C., Tsui, K. M., Tsukamoto, T., Tzanov, M., Uchida, Y., Vagins, M. R., Vargas, D., Varghese, M., Vasseur, G., Villa, E., Vinning, W. G. S., Virginet, U., Vladisavljevic, T., Wachala, T., Wakabayashi, D., Wallace, H. T., Walsh, J. G., Walter, C. W., Wan, L., Wang, X., Wang, Y., Wark, D., Wascko, M. O., Watanabe, E., Weber, A., Wendell, R. A., Wester, T., Wilking, M. J., Wilkinson, C., Wilson, S. T., Wilson, J. R., Wood, K., Wret, C., Wu, Y., Xia, J., Xie, Z., Xu, B. D., Xu, Y. -H., Yamamoto, K., Yamamoto, T., Yamauchi, K., Yanagisawa, C., Yang, G., Yang, B. S., Yang, J. Y., Yankelevich, A., Yano, T., Yasutome, K., Yershov, N., Yevarouskaya, U., Yokoyama, M., Yoo, J., Yoshida, T., Yoshida, S., Yoshimoto, Y., Yoshimura, N., Yoshioka, Y., Yu, M., Yu, I., Zaki, R., Zaldivar, B., Zalewska, A., Zalipska, J., Zaremba, K., Zarnecki, G., Zhang, J., Zhang, A. Q., Zhang, B., Zhao, X. Y., Zhong, H., Zhu, T., Ziembicki, M., Zimmerman, E. D., Zito, M., and Zsoldos, S.

Subjects
High Energy Physics - Experiment
Abstract

The Super-Kamiokande and T2K collaborations present a joint measurement of neutrino oscillation parameters from their atmospheric and beam neutrino data. It uses a common interaction model for events overlapping in neutrino energy and correlated detector systematic uncertainties between the two datasets, which are found to be compatible. Using 3244.4 days of atmospheric data and a beam exposure of $19.7(16.3) \times 10^{20}$ protons on target in (anti)neutrino mode, the analysis finds a 1.9$\sigma$ exclusion of CP-conservation (defined as $J_{CP}=0$) and a preference for the normal mass ordering., Comment: 12 pages, 4 figures

Published
2024

20. DESI Dark Energy Time Evolution is Recovered by Cosmologically Coupled Black Holes

Author

Croker, Kevin S., Tarlé, Gregory, Ahlen, Steve P., Cartwright, Brian G., Farrah, Duncan, Fernandez, Nicolas, and Windhorst, Rogier A.

Subjects
Astrophysics - Cosmology and Nongalactic Astrophysics
Abstract

Recent baryon acoustic oscillation (BAO) measurements by the Dark Energy Spectroscopic Instrument (DESI) provide evidence that dark energy (DE) evolves with time, as parameterized by a $w_0 w_a$ equation of state. Cosmologically coupled black holes (BHs) provide a DE source that naturally evolves with time, because BH production tracks cosmic star-formation. Using DESI BAO measurements and priors informed by Big Bang Nucleosynthesis, we measure the fraction of baryonic density converted into BHs, assuming that all DE is sourced by BH production. We find that the best-fit DE density tracks each DESI best-fit $w_0w_a$ model within $1\sigma$, except at redshifts $z \lesssim 0.2$, highlighting limitations of the $w_0w_a$ parameterization. Cosmologically coupled BHs produce $H_0 = (69.94 \pm 0.81)~\mathrm{km}\,\mathrm{s}^{-1}\,\mathrm{Mpc}^{-1}$, with the same $\chi^2$ as $\Lambda$CDM, and with two fewer parameters than $w_0w_a$. This value reduces tension with SH0ES to $2.7\sigma$ and is in excellent agreement with recent measurements from the Chicago-Carnegie Hubble Program. Because cosmologically coupled BH production depletes the baryon density established by primordial nucleosynthesis, these BHs provide a physical explanation for the ``missing baryon problem'' and the anomalously low sum of neutrino masses preferred by DESI. The global evolution of DE is an orthogonal probe of cosmological coupling, complementing constraints on BH mass-growth from elliptical galaxies, stellar binaries, globular clusters, the LIGO-Virgo-KAGRA merging population, and X-ray binaries. A DE density that correlates with cosmic star-formation: 1) is a natural outcome of cosmological coupling in BH populations; 2) eases tension between early and late-time cosmological probes; and 3) produces time-evolution toward a late-time $\Lambda$CDM cosmology different from Cosmic Microwave Background projections., Comment: JCAP published. 12+7 pages, 3 figures

Published
2024
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21. Finding Lensed Radio Sources with the VLA Sky Survey

Author

Martinez, Michael N., Gordon, Yjan A., Bechtol, Keith, Cartwright, Gillian, Ferguson, Peter S., and Gorsuch, Miranda

Subjects
Astrophysics - Astrophysics of Galaxies, Astrophysics - Cosmology and Nongalactic Astrophysics, Astrophysics - Instrumentation and Methods for Astrophysics
Abstract

Radio observations of strongly lensed objects are valuable as cosmological probes. Lensed radio sources have proven difficult to identify in large part due to the limited depth and angular resolution of the previous generation of radio sky surveys, and as such, only a few dozen lensed radio sources are known. In this work we present the results of a pilot study using the Very Large Array Sky Survey (VLASS) in combination with optical data to more efficiently identify lensed radio sources. We obtain high-resolution (0.2") VLA follow-up observations for 11 targets that we identify using three different techniques: i) a search for compact radio sources offset from galaxies with high lensing potential, ii) VLASS detections of known lensed galaxies, iii) VLASS detections of known lensed quasars. 5 of our targets show radio emission from the lensed images, including 100% of the lensed optical quasar systems. This work demonstrates the efficacy of combining deep and high-resolution wide-area radio and optical survey data to efficiently find lensed radio sources, and we discuss the potential impact of such an approach using next-generation surveys with the Vera C. Rubin Observatory, Euclid, and Nancy Grace Roman Space Telescope., Comment: 29 pages, 9 figures, 3 tables, submitted to AAS Journals

Published
2024
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22. Self-reported cancer-related cognitive impairment is associated with perturbed neurotransmission pathways.

Author

Oppegaard, Kate, Conley, Yvette, Paul, Steven, Cooper, Bruce, Harris, Carolyn, Shin, Joosun, Morse, Lisa, Levine, Jon, Cartwright, Frances, Roy, Ritu, Melisko, Michelle, Kober, Kord, Hammer, Marilyn, and Miaskowski, Christine

Subjects
Cancer, Chemotherapy-related cognitive impairment, Cognition, Gene expression, Neurotransmission, Pathway analysis, Patient-reported outcomes
Abstract

BACKGROUND: Cancer-related cognitive impairment (CRCI) is reported by 45% of patients with cancer. Significant gaps in knowledge remain regarding the mechanisms that underlie CRCI. OBJECTIVES: Using a data-driven approach, the study purpose was to evaluate for perturbed pathways associated with membership in the High versus the Low CRCI profiles. METHODS: Patients completed the Attentional Function Index six times over two cycles of chemotherapy. Using findings from a previous latent profile analysis, subgroups of patients with high versus low levels of CRCI were evaluated (i.e., High versus Low CRCI profiles). Gene expression was quantified using either ribonucleic (RNA)-sequencing or microarray analyses and pathway impact analyses were performed. Signaling pathways were defined using the Kyoto Encyclopedia of Genes and Genomes database. RESULTS: A total of 508 patients had data available for analysis. Of the 261 patients in the RNA-sequencing sample, 48.7% were in the High class and 51.3% were in the Low class. Of the 247 patients the microarray sample, 46.6% were in the High class and 53.4% were in the Low class. Pathway impact analyses identified seven perturbed pathways related to neurotransmission (i.e., glutamatergic synapse, GABAergic synapse, dopaminergic synapse, serotonergic synapse, long-term depression, cholinergic synapse, retrograde endocannabinoid signaling). CONCLUSIONS: This study is the first to describe associations between self-reported CRCI in patients receiving chemotherapy for breast, gastrointestinal, gynecological, or lung cancer and seven neurotransmission pathways. These findings provide new insights into potential targets for mechanistically based interventions.

Published
2024

23. Positive Effects of Speech and Language Therapy Group Interventions in Primary Progressive Aphasia: A Systematic Review

Author

Miyuki Watanabe, Jade Cartwright, and John E. Pierce

Abstract

Background: Primary progressive aphasia (PPA) is a neurodegenerative condition characterised by a prominent and progressive deterioration in language abilities, which significantly impacts quality of life and interpersonal relationships. Speech and language therapy plays a crucial role in offering interventions. Group intervention is one mode of delivery that could benefit communication functioning and overall wellbeing of people with PPA (pwPPA) and their care partners. Group interventions are also more efficient than one-to-one intervention and may facilitate peer support. Aims: The aim of this review was to systematically evaluate the current evidence for the effectiveness of speech and language therapy groups for pwPPA and their care partners. Specifically, this paper considered three questions: (1) What evidence-based speech and language therapy groups for pwPPA and their care partners have been reported to date? (2) Are group communication interventions effective in improving quality of life and communication function for pwPPA and their care partners? (3) Are group communication interventions that are designed for people with communication difficulties of other aetiologies (such as stroke) effective for pwPPA? In addition, this review aimed to describe the structure and content of groups, including aims, disciplines involved, size and frequency of group meetings, and outcome measures. Methods: MEDLINE, CINAHL and PsycINFO were used to retrieve articles of interest. A total of 10 studies published between 2009 and 2022 met the eligibility criteria and therefore were included in this study. Data were extracted from the articles regarding the structure and content of groups. Main Contribution: Although evidence is currently limited, results suggest that speech and language therapy group intervention can improve specific linguistic processes, the use of communication strategies and psychosocial well-being. The importance of multidisciplinary input and care partners' involvement in groups was highlighted, along with the benefits of creative non-verbal activities as tools for self-expression. There is also initial evidence that telehealth group provision and one-off group sessions may be feasible and can benefit psychosocial well-being. Lastly, intentional recruitment and explicit education on different aphasia types are described as important when pwPPA participate in groups with mixed diagnoses. Conclusions: The literature on speech and language therapy group interventions for PPA shows promise of positive effects on communication function and psychosocial well-being of both pwPPA and their care partners. Speech and language therapists can consider these published interventions when designing and implementing similar groups, but more robust evidence is required to confirm the relative effectiveness of this approach.

Published
2024
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25. Impact Evaluation of Imagine Math in a Charter School Network

Author

Freeman, Kayla, Cartwright, Macey, and Berrett, Andrew

Abstract

(Purpose) This study aimed to evaluate the efficacy of Imagine Math by comparing the performance of program users and non-users on the NWEA MAP Growth Math assessment. (Methods) Propensity score matching was utilized to compare statistically similar southeastern U.S. charter school students who used or did not use the Imagine Math program during the 2020-2021 school year. Imagine Math users and non-users were matched based on baseline performance and demographics and compared based on NWEA MAP Growth Math assessment performance. (Results) Use of Imagine Math was found to generate a positive and statistically significant impact on students' mathematics performance. Imagine Math users scored an average of 2.00 points higher on the Spring 2021 NWEA MAP Growth Math assessment than statistically similar non-user students. Grade-level models revealed statistically positive effects for Imagine Math students in Kindergarten through 8th grade with all findings being statistically significant except for Kindergarten. (Implications) Results show that students who used Imagine Math scored higher on the NWEA MAP Growth Math assessment than similar comparison students. Thus, this study provides evidence that the use of Imagine Math supports students' mathematics achievement. [This report was prepared by Imagine Learning.]

Published
2023

30. An example of the convergence of hydrodynamics in strong external fields

Author

Cartwright, Casey

Subjects
High Energy Physics - Theory, Condensed Matter - Strongly Correlated Electrons, Nuclear Theory
Abstract

The anti-de-Sitter/conformal field theory (AdS/CFT) correspondence is used to provide an estimate of the radius of convergence of the linearized gradient expansion of the hydrodynamic description of $\mathcal{N}=4$ supersymmetric Yang-Mills (SYM) theory minimally coupled to $U(1)$ gauge theory subjected to strong magnetic fields. The results of this work demonstrate that the dispersion relations of hydrodynamic modes continue to converge for magnetic field strengths far beyond those values for which a hydrodynamic description is expected. For magnetic field strengths much larger then the temperature scale the bulk dual interpolates between AdS$_{4+1}$ and the product of a Ba\~{n}ados-Teitelboim-Zanelli (BTZ) black hole and a two dimensional manifold (BTZ$_{2+1}\times \mathbb{R}^2$), and may be regarded as a renormalization group flow of the $3+1$ dimensional CFT to a $1+1$ dimensional CFT. In this regime, we clarify past literature on the quasi-normal mode (QNM) spectrum of bulk scalar fields by introducing a new way to classify the behavior of QNM collisions in the complex frequency and momentum plane., Comment: To appear in PRD. Accepted version: 16 pages, 6 figures

Published
2024

31. Water-Ice Dominated Spectra of Saturn's Rings and Small Moons from JWST

Author

Hedman, M. M., Tiscareno, M. S., Showalter, M. R., Fletcher, L. N., King, O. R. T., Harkett, J., Roman, M. T., Rowe-Gurney, N., Hammel, H. B., Milam, S. N., Moutamid, M. El, Cartwright, R. J., de Pater, I., and Molter, E.

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

JWST measured the infrared spectra of Saturn's rings and several of its small moons (Epimetheus, Pandora, Telesto and Pallene) as part of Guaranteed Time Observation program 1247. The NIRSpec instrument obtained near-infrared spectra of the small moons between 0.6 and 5.3 microns, which are all dominated by water-ice absorption bands. The shapes of the water-ice bands for these moons suggests that their surfaces contain variable mixes of crystalline and amorphous ice or variable amounts of contaminants and/or sub-micron ice grains. The near-infrared spectrum of Saturn's A ring has exceptionally high signal-to-noise between 2.7 and 5 microns and is dominated by features due to highly crystalline water ice. The ring spectrum also confirms that the rings possess a 2-3% deep absorption at 4.13 microns due to deuterated water-ice previously seen by the Visual and Infrared Mapping Spectrometer onboard the Cassini spacecraft. This spectrum also constrains the fundamental absorption bands of carbon dioxide and carbon monoxide and may contain evidence for a weak aliphatic hydrocarbon band. Meanwhile, the MIRI instrument obtained mid-infrared spectra of the rings between 4.9 and 27.9 microns, where the observed signal is a combination of reflected sunlight and thermal emission. This region shows a strong reflectance peak centered around 9.3 microns that can be attributed to crystalline water ice. Since both the near and mid-infrared spectra are dominated by highly crystalline water ice, they should provide a useful baseline for interpreting the spectra of other objects in the outer solar system with more complex compositions., Comment: Accepted for Publication in JGR Planets

Published
2024

32. Competing structures in a minimal double-well potential model of condensed matter

Author

Cartwright, Julyan H. E., Escribano, Bruno, Roldán-Vargas, Sándalo, and Sainz-Díaz, C. Ignacio

Subjects
Condensed Matter - Materials Science, Condensed Matter - Disordered Systems and Neural Networks, Condensed Matter - Statistical Mechanics
Abstract

The microscopic structure of several amorphous substances often reveals complex patterns such as medium- or long-range order, spatial heterogeneity, and even local polycrystallinity. To capture all these features, models usually incorporate a refined description of the particle interaction that includes an ad hoc design of the inside of the system constituents, and use temperature as a control parameter. We show that all these features can emerge from a minimal athermal two-dimensional model where particles interact isotropically by a double-well potential, which includes an excluded volume and a maximum coordination number. The rich variety of structural patterns shown by this simple geometrical model apply to a wide range of real systems including water, silicon, and different amorphous materials., Comment: 6 pages, 5 figures

Published
2024

33. Revealing Callisto's carbon-rich surface and CO2 atmosphere with JWST

Author

Cartwright, Richard J., Villanueva, Geronimo L., Holler, Bryan J., Camarca, Maria, Faggi, Sara, Neveu, Marc, Roth, Lorenz, Raut, Ujjwal, Glein, Christopher R., Castillo-Rogez, Julie C., Malaska, Michael J., Bockelee-Morvan, Dominique, Nordheim, Tom A., Hand, Kevin P., Strazzulla, Giovanni, Pendleton, Yvonne J., de Kleer, Katherine, Beddingfield, Chloe B., de Pater, Imke, Cruikshank, Dale P., and Protopapa, Silvia

Subjects
Astrophysics - Earth and Planetary Astrophysics
Abstract

We analyzed spectral cubes of Callisto's leading and trailing hemispheres, collected with the NIRSpec Integrated Field Unit (G395H) on the James Webb Space Telescope. These spatially resolved data show strong 4.25-micron absorption bands resulting from solid-state 12CO2, with the strongest spectral features at low latitudes near the center of its trailing hemisphere, consistent with radiolytic production spurred by magnetospheric plasma interacting with native H2O mixed with carbonaceous compounds. We detected CO2 rovibrational emission lines between 4.2 and 4.3 microns over both hemispheres, confirming the global presence of CO2 gas in Callisto's tenuous atmosphere. These results represent the first detection of CO2 gas over Callisto's trailing side. The distribution of CO2 gas is offset from the subsolar region on either hemisphere, suggesting that sputtering, radiolysis, and geologic processes help sustain Callisto's atmosphere. We detected a 4.38-micron absorption band that likely results from solid-state 13CO2. A prominent 4.57-micron absorption band that might result from CN-bearing organics is present and significantly stronger on Callisto's leading hemisphere, unlike 12CO2, suggesting these two spectral features are spatially anti-associated. The distribution of the 4.57-micron band is more consistent with a native origin and/or accumulation of dust from Jupiter's irregular satellites. Other, more subtle absorption features could result from CH-bearing organics, CO, carbonyl sulfide (OCS), and Na-bearing minerals. These results highlight the need for preparatory laboratory work and improved surface-atmosphere interaction models to better understand carbon chemistry on the icy Galilean moons before the arrival of NASA's Europa Clipper and ESA's JUICE spacecraft., Comment: Accepted in AAS Planetary Science Journal, January 2024

Published
2024

36. Expression of foetal gene Pontin is essential in protecting heart against pathological remodelling and cardiomyopathy

Author

Bayu Lestari, Ardiansah Bayu Nugroho, Thuy Anh Bui, Binh Nguyen, Nicholas Stafford, Sukhpal Prehar, Min Zi, Ryan Potter, Efta Triastuti, Florence M. Baudoin, Alicia D’Souza, Xin Wang, Elizabeth J. Cartwright, and Delvac Oceandy

Subjects
Science
Abstract

Abstract Cardiac remodelling is a key process in the development of heart failure. Reactivation of foetal cardiac genes is often associated with cardiac remodelling. Here we study the role of Pontin (Ruvbl1), which is highly expressed in embryonic hearts, in mediating adverse remodelling in adult mouse hearts. We observe that Pontin deficiency in cardiomyocytes leads to induced apoptosis, increased hypertrophy and fibrosis, whereas Pontin overexpression improves survival, increases proliferation and reduces the hypertrophic response. Moreover, RNAseq analysis show that genes involved in cell cycle regulation, cell proliferation and cell survival/apoptosis are differentially expressed in Pontin knockout. Specifically, we detect changes in the expression of Hippo pathway components in the Pontin knockout mice. Using a cellular model we show that Pontin induces YAP activity, YAP nuclear translocation, and transcriptional activity. Our findings identify Pontin as a modulator of adverse cardiac remodelling, possibly via regulation of the Hippo pathway. This study may lead to the development of a new approach to control cardiac remodelling by targeting Pontin.

Published
2025
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37. The safety and tolerability of berdazimer gel 10.3% in Japanese patients with molluscum contagiosumCapsule Summary

Author

Makoto Kawashima, MD, PhD, Yoshiyuki Kaneko, BS, Manami Sawasaki, BS, Kyohei Masubuchi, BS, Hiroyuki Yasukawa, BS, Saki Okada, BS, Carolyn Enloe, MPH, Carri Geer, PhD, Martina Cartwright, PhD, Tomoko Maeda-Chubachi, MD, PhD, and Takeshi Tani, BS

Subjects
berdazimer gel, Japanese patients, molluscum contagiosum, nitric oxide, Dermatology, RL1-803
Abstract

Background: Molluscum contagiosum (MC) is a contagious viral skin infection. Berdazimer gel, 10.3% (SB206 12%) is approved in the United States as the first topical, at-home MC prescription medication. Objective: To assess safety and tolerability of SB206 12% in Japanese patients with MC. Methods: SKN15B01 (JRCT2031230123) was a phase 2, multicenter, single-group, open-label study in Japanese patients ≥2 years old with 3-70 baseline MC lesions. Patients with only periocular MC and/or immunosuppression were excluded. SB206 12% was applied once daily to lesions for 12 weeks. Safety endpoints included adverse events and local skin reactions. Exploratory efficacy endpoints included percentage of patients with complete lesion clearance and lesion count percent change from baseline. Results: Twenty patients (12 males, 8 females) with mean (range) age of 5.2 (3-13) years and mean (range) baseline lesion counts of 22.5 (8-44). Complete clearance and percent change from baseline at week 12 were 60% and −89.2%, respectively. The most common treatment-related adverse events were application site-erythema (25%, n = 5), -pain (25%, n = 5), -pruritis (25%, n = 5), and -dermatitis (20%, n = 4), all mild/moderate in severity. Limitations: Single-group study; small sample size. Conclusion: Safety and efficacy of berdazimer gel, 10.3% in Japanese patients were favorable and consistent with previous studies.

Published
2025
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38. Cryopreserved human alternatively activated macrophages promote resolution of acetaminophen-induced liver injury in mouse

Author

Maria Elena Candela, Melisande Addison, Rhona Aird, Tak-Yung Man, Jennifer A. Cartwright, Candice Ashmore-Harris, Alastair M. Kilpatrick, Philip J. Starkey Lewis, Anna Drape, Mark Barnett, Donna Mitchell, Colin McLean, Neil McGowan, Marc Turner, James W. Dear, and Stuart J. Forbes

Subjects
Medicine
Abstract

Abstract Acute liver failure is a rapidly progressing, life-threatening condition most commonly caused by an overdose of acetaminophen (paracetamol). The antidote, N-acetylcysteine (NAC), has limited efficacy when liver injury is established. If acute liver damage is severe, liver failure can rapidly develop with associated high mortality rates. We have previously demonstrated that alternatively, activated macrophages are a potential therapeutic option to reverse acute liver injury in pre-clinical models. In this paper, we present data using cryopreserved human alternatively activated macrophages (hAAMs)—which represent a potential, rapidly available treatment suitable for use in the acute setting. In a mouse model of APAP-induced injury, peripherally injected cryopreserved hAAMs reduced liver necrosis, modulated inflammatory responses, and enhanced liver regeneration. hAAMs were effective even when administered after the therapeutic window for NAC. This cell therapy approach represents a potential treatment for APAP overdose when NAC is ineffective because liver injury is established.

Published
2025
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39. Insulin, IGF-I, and lactoferrin concentrations and yields and their associations with other components within colostrum, transition, and whole milk of primiparous and multiparous Holstein cattle

Author

A.J. Fischer-Tlustos, S.L. Cartwright, K.S. Hare, D.J. Innes, J.P. Cant, M. Tortades, F. Fabregas, A. Aris, E. Garcia-Fruitos, and M.A. Steele

Subjects
Dairy processing. Dairy products, SF250.5-275
Abstract

The primary objective of the study was to characterize concentrations and yields of lactoferrin (LF), insulin, and IGF-I in colostrum, transition milk (TM), and whole milk (WM) of multiparous (MP) and primiparous (PP) cows. A secondary objective was to determine associations between colostrum and TM components (fat, protein, lactose), IgG, and bioactive compounds (oligosaccharides, LF, insulin, IGF-I; defined as compounds present in micro quantities that stimulate physiological responses systemically or locally within the neonate). Holstein cows (10 MP and 10 PP) were assigned to the study at calving and colostrum was collected 5.3 ± 0.7 h (mean ± SE) after calving, followed by twice daily sampling of milkings 2–5 (TM) and milking 12 (WM). Colostrum, TM, and WM samples were analyzed by commercial ELISA to determine concentrations of LF, insulin, and IGF-I. Concentrations of insulin, IGF-I, and LF were greatest in colostrum compared with all other milkings. Similarly, IGF-I and LF yields were greatest in colostrum, whereas insulin yield was greatest in colostrum and milking 2 compared with milking 4, 5, and 12. Primiparous cows had greater insulin and lower LF concentrations in colostrum compared with MP cows. Additionally, lower LF concentrations in PP cows persisted through milkings 2 and 3. The majority of associations between components and bioactive compounds in colostrum were positive; however, correlations were different between PP and MP cows. Specifically, there were a greater number of strong (ρ > 0.80) correlations between components and IgG in PP cows. In contrast, MP cows demonstrated a greater number of strong correlations among bioactive compounds. To the authors' knowledge, this study is the first to characterize the yields of IGF-I, LF, and insulin during the colostral (collection within 6 h) and TM period in both MP and PP cows. The study findings indicate that parity influences the levels of LF and insulin, but not IGF-I. Our study also uniquely demonstrates associations between early lactation components and bioactive compounds, which are not consistent among parities.

Published
2025
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40. A Classroom Market Experiment: Data and Reflections

Author

Anna Cartwright and Edward Cartwright

Abstract

In this article, the authors analyze data accumulated over 10+ years of teaching market interaction using a simple classroom experiment. The experiment is designed to teach first-year undergraduate students the basics of supply and demand and market efficiency. In total, they analyze data from 85 teaching sessions and 243 individual markets. They find that traded prices typically (90% of the time) move in accordance with market equilibrium comparative statics. They also find that average traded prices are rarely (5% of the time) consistent with market equilibrium but typically (70% of the time) "close" to the equilibrium. The traded quantity is often (60% of the time) more than equilibrium, which results in a loss of efficiency. The law of one price is strongly rejected.

Published
2024
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41. Game Theoretic Modelling of a Ransom and Extortion Attack on Ethereum Validators

Author

Bhudia, Alpesh, Cartwright, Anna, Cartwright, Edward, Hurley-Smith, Darren, and Hernandez-Castro, Julio

Subjects
Computer Science - Computer Science and Game Theory, Computer Science - Cryptography and Security
Abstract

Consensus algorithms facilitate agreement on and resolution of blockchain functions, such as smart contracts and transactions. Ethereum uses a Proof-of-Stake (PoS) consensus mechanism, which depends on financial incentives to ensure that validators perform certain duties and do not act maliciously. Should a validator attempt to defraud the system, legitimate validators will identify this and then staked cryptocurrency is `burned' through a process of slashing. In this paper, we show that an attacker who has compromised a set of validators could threaten to perform malicious actions that would result in slashing and thus, hold those validators to ransom. We use game theory to study how an attacker can coerce payment from a victim, for example by deploying a smart contract to provide a root of trust shared between attacker and victim during the extortion process. Our game theoretic model finds that it is in the interests of the validators to fully pay the ransom due to a lack of systemic protections for validators. Financial risk is solely placed on the victim during such an attack, with no mitigations available to them aside from capitulation (payment of ransom) in many scenarios. Such attacks could be disruptive to Ethereum and, likely, to many other PoS networks, if public trust in the validator system is eroded. We also discuss and evaluate potential mitigation measures arising from our analysis of the game theoretic model.

Published
2023

42. Connecting Mathematical Processes and Conceptual Body Movement. Embodied Learning in Early Mathematics. [Symposium]

Author

Mathematics Education Research Group of Australasia (MERGA), Cartwright, Katherin, and Way, Jennifer

Abstract

Conceptual body movement in education is an external representation mode that research suggests can support children's learning about mathematical phenomena. Children's learning and understanding of mathematical concepts and processes, such as number structure and relationships, number sequencing, position, or geometric properties, may be supported by experiences using their own body movements. The aim of this paper is to share classroom activities trialled within the Embodied Learning in Early Mathematics and Science project in 7 classrooms focusing on conceptual body movements. The results share what was trialled, and what was observed in relation to children's learning of mathematical processes. Findings revealed that body movement is a helpful mode through which young children can learn and communicate mathematical understanding.

Published
2023

43. Finger Tracing, Noticing Structures and Drawing. Embodied Learning in Early Mathematics [Symposium]

Author

Mathematics Education Research Group of Australasia (MERGA), Way, Jennifer, and Cartwright, Katherin

Abstract

This paper presents an initial analysis of 10 Preschool children's responses to a look-draw-trace-draw task. The findings suggest that figure-tracing helped half the children to produce a more accurate representation of the geometric figure presented to them, in their second drawing.

Published
2023

44. Changes in Year 2 Children's Drawings of a Subtraction Story. Embodied Learning in Early Mathematics. [Symposium]

Author

Mathematics Education Research Group of Australasia (MERGA), Way, Jennifer, and Cartwright, Katherin

Abstract

There is an educational expectation that children's natural drawing will develop into proficient mathematical representations and formal diagrams, yet there is little research available to guide the assessment and development of children's mathematical drawing skills. The aim of this paper is to explore how Year 2 children (approx. 7 years) chose to represent their interpretations of a simple story that is suggestive of the take-away subtraction process, and what changes occurred when the drawing task was repeated 6 months later. Analysis of 13 pairs of drawings revealed changes in what the children drew (categories of number representations) and how they drew it (style). The findings suggest that substantial change in children's representational ability can occur in within 6 months.

Published
2023

45. Interpreting Young Children's Multiplicative Strategies through Their Drawn Representations

Author

Katherin Cartwright

Abstract

The exploration of children's drawings as mathematical representations is a current focus in early years mathematics education research. This paper presents a qualitative analysis of 72 kindergarten to Grade 3 (5 to 8 years old) children's drawings produced during problem-solving tasks centred on multiplicative strategies. Existing frameworks for the developmental sequence of mathematical drawings and the progression of children's strategies for multiplicative situations were an interpretive lens through which to analyse the drawings. Children used pictographic and iconic drawing types to represent the "story" in the problem and the multiplicative strategies employed to solve the tasks. Exploration of the children's drawings suggested that as children's drawings become more structural, schematic in nature, it may be easier for children to show their understanding of the structural elements of multiplicative relationships. Results revealed that structural elements of multiplicative relationships were more easily seen in iconic representations; however, both pictographic and iconic drawings were useful to observe counting, additive, and multiplicative strategies when mathematical elements of the problem were visible. Additional representations attached to the drawings (e.g. numerical) were needed to confirm children's strategies when their drawings lacked structure. These findings have implications for how young children's drawings are interpreted by classroom teachers. The interpretation of these drawings suggested that some children may not yet realise how their drawings in mathematics need to shift from illustrations of the problem's story context to representing mathematical ideas and processes -- which requires intentional teaching of the purpose of drawings for mathematical contexts.

Published
2024
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47. Multi-label Open-set Audio Classification

Author

Sridhar, Sripathi and Cartwright, Mark

Subjects
Computer Science - Sound, Electrical Engineering and Systems Science - Audio and Speech Processing
Abstract

Current audio classification models have small class vocabularies relative to the large number of sound event classes of interest in the real world. Thus, they provide a limited view of the world that may miss important yet unexpected or unknown sound events. To address this issue, open-set audio classification techniques have been developed to detect sound events from unknown classes. Although these methods have been applied to a multi-class context in audio, such as sound scene classification, they have yet to be investigated for polyphonic audio in which sound events overlap, requiring the use of multi-label models. In this study, we establish the problem of multi-label open-set audio classification by creating a dataset with varying unknown class distributions and evaluating baseline approaches built upon existing techniques., Comment: Published at the Workshop on Detection and Classification of Acoustic Scenes and Events, 2023 (DCASE 2023)

Published
2023

48. Higher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trialResearch in context

Author

O. Abani, A. Abbas, F. Abbas, J. Abbas, K. Abbas, M. Abbas, S. Abbasi, H. Abbass, A. Abbott, N. Abdallah, A. Abdelaziz, M. Abdelfattah, B. Abdelqader, A. Abdul, B. Abdul, S. Abdul, A. Abdul Rasheed, A. Abdulakeem, R. Abdul-Kadir, A. Abdullah, A. Abdulmumeen, R. Abdul-Raheem, N. Abdulshukkoor, K. Abdusamad, Y. Abed El Khaleq, M. Abedalla, A. Abeer Ul Amna, L. Abel, K. Abernethy, M. Abeywickrema, C. Abhinaya, A. Abidin, A. Aboaba, A. Aboagye-Odei, C. Aboah, H. Aboelela, H. Abo-Leyah, K. Abouelela, A. Abou-Haggar, M. Abouibrahim, A. Abousamra, M. Abouzaid, M. Abraham, T. Abraham, A. Abraheem, J. Abrams, R. Abrams, H.J. Abu, A. Abu-Arafeh, S.M. Abubacker, A. Abung, Y. Abusamra, Y. Aceampong, A. Achara, D. Acharya, F. Acheampong, P. Acheampong, S. Acheampong, J. Acheson, S. Achieng, A. Acosta, R. Acquah, C. Acton, J. Adabie-Ankrah, P. Adair, A.S. Adam, F. Adam, M. Adam, H. Adamali, M. Adamczyk, C. Adams, D. Adams, K. Adams, L. Adams, N. Adams, R. Adams, T. Adams, L. Adamu-Ikeme, K. Adatia, K. Adcock, L. Addai-Boampong, A. Addo, O. Adeagbo, A. Adebiyi, O. Adedeji, Y. Adegeye, K. Adegoke, V. Adell, S. Adenwalla, F.W. Adeoye, O.A. Adesemoye, E.O. Adewunmi, A. Adeyanju, J. Adeyemi, T. Adeyemo, B. Adhikari, S.A. Adhikari, R. Adhikary, A. Aditya, P. Adjepong, G. Adkins, A. Adnan, M. Adriaanse, J. Aeron-Thomas, D. Affleck, C. Afnan, M. Afridi, P. Afrim, F.A. Afriyie, Z.A. Aftab, A. Afum-Adjei Awuah, M. Agarwal, P.N. Agasiya, R. Agbeko, C. Agbo, S. Aggarwal, A. Aghababaie, L. Aguilar Jimenez, J.A. Agyekum, K. Agyen, E.K. Ahadome, S. Ahamed Sadiq, M.H. Ahammed Nazeer, M. Ahmad, S. Ahmad, A. Ahmed, B.A.R. Ahmed, B. Ahmed, F. Ahmed, H. Ahmed, I. Ahmed, K. Ahmed, L. Ahmed, M. Ahmed, M.C. Ahmed, M.S. Ahmed, N. Ahmed, O. Ahmed, R.A. Ahmed, R. Ahmed, S. Ahmed, S.G. Ahmed, S.H. Ahmed, R. Ahmed Ali, B. Ahmed Mohamud, S. Ahmer, A. Ahonia, C. Aidoo, C. Aiken, D. Ail, M. Ainsworth, M. Aissa, L. Aitken, B. Ajay, A. Ajibode, A. Ajmi, N. Akhtar, S. Akili, B. Akinbiyi, O. Akindolie, Y. Akinfenwa, O. Akinkugbe, I. Akinpelu, M. Akram, O. Aktinade, U. Akudi, A.S.A.R. Al Aaraj, A. Al Balushi, M. Al Dakhola, A. Al Swaifi, E. Al-Abadi, A. Alabi, N. Aladangady, M. Alafifi, A. Alam, S. Alam, A. Al-Asadi, K. Alatzoglou, P. Albert, A. Albertus, L. Albon, A. Alcala, G. Alcorn, S. Alcorn, A. Aldana, D. Alderdice, A. Aldesouki, R. Aldouri, J. Aldridge, N. Aldridge, R. Ale, R.M. Ale, A. Alegria, A. Alexander, C. Alexander, J. Alexander, P.D.G. Alexander, J. Al-fori, L. Alghazawi, O. Alhabsha, B. Al-Hakim, R. Alhameed, M. Al-Hayali, S. Al-Hity, A. Ali, F.R. Ali, J. Ali, M. Ali, M.S. Ali, N. Ali, O. Ali, R. Ali, S. Ali, E. Aliberti, J. Alin, A. Alina, A. Alipustain, B. Alisjahbana, F. Aliyuda, K. Alizadeh, M. Al-Jibury, S. Al-Juboori, M. Al-Khalil, A. Alkhudhayri, M. Alkhusheh, F. Allan, N. Allan, A. Allanson, R. Allcock, E. Allen, J. Allen, K. Allen, L. Allen, P. Allen, R. Allen, S. Allen, T. Allen, A. Alli, K. Allison, B. Allman, H.K. Allsop, L. Allsop, D. Allsup, A.F.T. Almahroos, H. Al-Moasseb, M. Al-Obaidi, L. Alomari, A. Al-Rabahi, B. Al-Ramadhani, Z. Al-Saadi, R. Al-Sammarraie, I. Alshaer, R. Al-Shahi Salman, W. Al-Shamkhani, F. Alsheikh, B. Al-Sheklly, S. Altaf, A. Alty, M. Alvarez, M. Alvarez Corral, E. Alveyn, M. Alzetani, S. Amamou, N. Amar, S. Ambalavanan, R. Ambrogetti, C. Ambrose, A. Ameen, A. Amelia Ganefianty, K. Ames, M.R. Amezaga, A. Amin, K. Amin, S. Amin, T. Amin, B. Amit, A. Amjad, N. Amjad, J. Amoah-Dankwa, A. Amoako-Adusei, V. Amosun, M. Amsal, K. Amsha, J. Amuasi, N. Amutio Martin, P. Amy, A. Anada, A. Anand, S. Anandappa, S.D. Anantapatnaikuni, N.K.N. Andari, E. Anderson, J. Anderson, L. Anderson, M. Anderson, N. Anderson, R. Anderson, S. Anderson, W. Anderson, P. Andreou, A. Andrews, J. Andrews, K. Aneke, A. Ang, W.W. Ang, T. Angel, A. Angela, P. Angelini, L. Anguvaa, O. Anichtchik, M. Anim-Somuah, K. Aniruddhan, J. Annett, L. Anning, M. Ansah, P.J. Anstey, R. Anstey, A. Anthony, A. Anthony-Pillai, P. Antill, Z. Antonina, V. Anu, M. Anwar, S. Anwar, E. Apetri, A. Apostolopoulos, S. Appleby, D. Appleyard, M.F. Aquino, B. Araba, S. Aransiola, M. Araujo, A. Archer, D. Archer, S. Archer, D. Arcoria, C. Ardley, G. Arhin-Sam, A.-M. Arias, O. Aribike, R. Arimoto, N.L.P.E. Arisanti, C. Arkley, C. Armah, I. Armata, J. Armistead, A. Armitage, C. Armstrong, M. Armstrong, S. Armstrong, W. Armstrong, P. Armtrong, H. Arndt, C. Arnison-Newgass, D. Arnold, R. Arnold, A. Arnott, D. Arora, K. Arora, P. Arora, R. Arora, A. Arter, A. Arthur, N.M. Artini, A. Arumaithurai, A. Arya, R. Arya, D. Aryal, D. Asandei, G.A. Asare, A. Asghar, M. Asghar, A. Ashab, C. Ashbrook-Raby, H. Ashby, J. Ashcroft, S. Ashcroft, G. Asher, Z. Ashfak, A. Ashfaq, H.A. Asiamah, A. Ashish, D. Ashley, S. Ashman-Flavell, S. Ashok, A.-E.-A. Ashour, M.Z. Ashraf, S. Ashraf, M.B. Ashraq, D. Ashton, S. Ashton, A. Ashworth, F.J. Ashworth, R. Ashworth, A. Aslam, I. Aslam, S. Aslam, L. Aslett, H. Asogan, A. Asrar, O. Assaf, R. Astin-Chamberlain, Y.E. Atabudzi, P. Athavale, D. Athorne, B. Atkins, C. Atkins, S. Atkins, J. Atkinson, V. Atkinson, A. Atomode, B. Atraskiewicz, A.A. Attia, E. Attubato, M. Attwood, P. Aubrey, Z. Auer, A. Aujayeb, A.T. Aung, H. Aung, H.W.W. Aung, K.K. Aung, K.T. Aung, N. Aung, Y. Aung, Z.M. Aung, E. Austin, K. Austin, A. Auwal, M. Avari, M. Avery, N. Aveyard, J. Avis, G. Aviss, C. Avram, P. Avram, A. Awadelkareem, G. Awadzi, M. Awaly, A. Awan, S. Awisi, A. Aya, E. Ayaz, J.M. Ayerh, A. Ayers, J. Azam, A. Azeem, M. Azharuddin, A. Aziz, G. Aziz, I. Aziz, N. Aziz, A. Azkoul, A. Azman Shah, G. Azzopardi, H. Azzoug, F. Babatunde, M. Babi, B. Babiker, G. Babington, M. Babirecki, M. Babores, A.O. Babs-Osibodu, T. Bac, S. Bacciarelli, R. Bachar, M.-E. Bachour, A. Bachti, G. Bacon, J. Bacon, B. Badal, A. Badat, M. Bader, G.R. Badhan, S. Badhrinarayanan, J.P. Bae, A. Baggaley, A. Baggott, G. Bagley, D. Bagmane, L. Bagshaw, K. Bahadori, Y. Bahurupi, A. Bailey, J. Bailey, K. Bailey, L. Bailey, M.A. Bailey, M. 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Young, G. Young, L. Young, A. Yousafzar, S. Youssouf, A. Yousuf, H. Yovita, C. Yu, J.S.J. Yuan, N. Yufaniaputri, B. Yung, D. Yusef, S. Yusef, I. Yusuf, A.-S. Zafar, S. Zagalo, S. Zaher, A. Zahoor, M. Zainab, T. Zak, K. Zaki, N. Zakir, K. Zalewska, A. Zamalloa, M. Zaman, S. Zaman, J. Zamikula, L. Zammit, M. Zammit-Mangion, M. Zawadzka, M. Zayed, E. Zebracki, D. Zehnder, L. Zeidan, D. Zeinali, J. Zhang, X. Zhao, D. Zheng, D. Zhu, M. Zia, O. Zibdeh, R. Zill-E-Huma, E.T. Zin, E. Zincone, G. Zindoga, E. Zinkin, V. Zinyemba, C. Zipitis, L. Zitter, A. Zmierczak, G. Zubikarai, A. Zubir, N. Zuhra, R. Zulaikha, S. Zulfikar, C. Zullo, and A. Zuriaga-Alvaro

Subjects
COVID-19, Corticosteroid, Dexamethasone, Mortality, Clinical trial, Medicine (General), R5-920
Abstract

Summary: Background: Low dose corticosteroids (e.g., 6 mg dexamethasone) have been shown to reduce mortality for hypoxic COVID-19 patients. We have previously reported that higher dose corticosteroids cause harm in patients with clinical hypoxia but not receiving ventilatory support (the combination of non-invasive mechanical ventilation, including high-flow nasal oxygen, continuous positive airway pressure and bilevel positive airway pressure ventilation, and invasive mechanical ventilation or extra-corporeal membrane oxygenation), but the balance of efficacy and safety in patients receiving ventilatory support is uncertain. Methods: This randomised, controlled, open-label platform trial (Randomised Evaluation of COVID-19 Therapy [RECOVERY]) assessed multiple possible treatments in patients hospitalised for COVID-19. Eligible and consenting adult patients receiving ventilatory support were randomly allocated (1:1) to either usual care with higher dose corticosteroids (dexamethasone 20 mg once daily for 5 days followed by 10 mg once daily for 5 days or until discharge if sooner) or usual standard of care alone (which includes dexamethasone 6 mg once daily for 10 days or until discharge if sooner). The primary outcome was 28-day mortality; secondary outcomes were duration of hospitalisation and (among participants not on invasive mechanical ventilation at baseline) the composite of invasive mechanical ventilation or death. Recruitment closed on 31 March 2024 when funding for the trial ended. The RECOVERY trial is registered with ISRCTN (50189673) and clinicaltrials.gov (NCT04381936). Findings: Between 25 May 2021 and 9 January 2024, 477 COVID-19 patients receiving ventilatory support were randomly allocated to receive usual care plus higher dose corticosteroids vs. usual care alone (of whom 99% received corticosteroids during the follow-up period). Of those randomised, 221 (46%) were in Asia, 245 (51%) in the UK and 11 (2%) in Africa. 143 (30%) had diabetes mellitus. Overall, 86 (35%) of 246 patients allocated to higher dose corticosteroids vs. 86 (37%) of 231 patients allocated to usual care died within 28 days (rate ratio [RR] 0.87; 95% CI 0.64–1.18; p = 0.37). There was no significant difference in the proportion of patients discharged from hospital alive within 28 days (128 [52%] in the higher dose corticosteroids group vs. 120 [52%] in the usual care group; RR 1.04, 0.81–1.33]; p = 0.78). Among those not on invasive mechanical ventilation at baseline, there was no clear reduction in the proportion meeting the composite endpoint of invasive mechanical ventilation or death (76 [37%] of 206 vs. 93 [45%] of 205; RR 0.79 [95% CI 0.63–1.00]; p = 0.05). Interpretation: In patients hospitalised for COVID-19 receiving ventilatory support, we found no evidence that higher dose corticosteroids reduced the risk of death compared to usual care, which included low dose corticosteroids. Funding: UK Research and Innovation (Medical Research Council) and National Institute for Health Research (Grant ref: MC_PC_19056), and Wellcome Trust (Grant Ref: 222406/Z/20/Z).

Published
2025
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49. Various types of stress and greater use of disengagement coping are associated with worse sleep disturbance in oncology patients undergoing chemotherapy

Author

Calvo‐Schimmel, Alejandra, Paul, Steven M, Cooper, Bruce A, Harris, Carolyn, Shin, Joosun, Oppegaard, Kate, Hammer, Marilyn J, Cartwright, Frances, Conley, Yvette P, Kober, Kord M, Levine, Jon D, and Miaskowski, Christine

Subjects
Psychology, Sleep Research, Behavioral and Social Science, Cancer, Mental Health, Clinical Research, 7.1 Individual care needs, Humans, Coping Skills, Neoplasms, Psychological Tests, Resilience, Psychological, Self Report, Sleep, Sleep Wake Disorders, Stress, Psychological, cancer, chemotherapy, coping, resilience, sleep disturbance, stress, Public Health and Health Services, Business and Management, Psychiatry, Biomedical and clinical sciences
Abstract

Various types of stress and the choice of coping strategies may be risk factors for higher levels of sleep disturbance in oncology patients. Purposes were to evaluate for differences in global, cancer-specific, and cumulative life stress, as well as resilience and the use of coping strategies among three subgroups of patients with distinct sleep disturbance profiles (i.e., Low, High, Very High). Oncology outpatients (n = 1331) completed measures of global (Perceived Stress Scale), cancer-specific (Impact of Event Scale-Revised), and cumulative life (Life Stressor Checklist-Revised) stress, resilience (Connor-Davidson Resilience Scale) and coping (Brief Cope) prior to their second or third cycle of chemotherapy. Sleep disturbance was assessed six times over two chemotherapy cycles. Differences were evaluated using parametric and non-parametric tests. All stress measures showed a dose response effect (i.e., as the sleep disturbance profile worsened, levels of all types of stress increased). Compared to Low class, the other two classes reported higher levels of global perceived stress and higher occurrence rates and effect from previous stressful life events. Impact of Event Scale-Revised scores for the Very High class indicated post-traumatic symptomatology. Patients in High and Very High classes had resilience scores below the normative score for the United States population and used a higher number of disengagement coping strategies. Our findings suggest that very high levels of sleep disturbance are associated with higher levels of various types of stress, lower levels of resilience, and higher use of disengagement coping strategies. Clinicians need to perform routine assessments and implement symptom management interventions to reduce stress and encourage the use of engagement coping strategies.

Published
2024

50. Common and distinct risk factors that influence more severe and distressing shortness of breath profiles in oncology outpatients.

Author

Shin, Joosun, Hammer, Marilyn, Cooley, Mary, Cooper, Bruce, Paul, Steven, Cartwright, Frances, Kober, Kord, Conley, Yvette, Levine, Jon, and Miaskowski, Christine

Subjects
cancer, chemotherapy, distress, dyspnea, shortness of breath
Abstract

BACKGROUND: Shortness of breath occurs in 10%-70% of oncology patients. Very little is known about interindividual variability in its severity and distress and associated risk factors. Using latent profile analyses (LPAs), purpose was to identify subgroups of patients with distinct severity and distress profiles for shortness of breath as single symptom dimensions. In addition, a joint LPA was done using patients severity AND distress ratings. For each of the three LPAs, differences among the shortness of breath classes in demographic, clinical, symptom, stress, and resilience characteristics were evaluated. METHODS: Patients completed ratings of severity and distress from shortness of breath a total of six times over two cycles of chemotherapy. All of the other measures were completed at enrollment (i.e., prior to the second or third cycle of chemotherapy). Separate LPAs were done using ratings of severity and distress, as well as a joint analysis using severity AND distress ratings. Differences among the latent classes were evaluated using parametric and nonparametric tests. RESULTS: For severity, two classes were identified (Slight to Moderate [91.6%] and Moderate to Severe [8.4%]). For distress, two classes were identified (A Little Bit to Somewhat [83.9%] and Somewhat to Quite a Bit [16.1%]). For the joint LPA, two classes were identified (Lower Severity and Distress [79.9%] and Higher Severity and Distress [20.1%]). While distinct risk factors were associated with each of the LPAs, across the three LPAs, the common risk factors associated with membership in the worse class included: a past or current history of smoking, poorer functional status, and higher comorbidity burden. In addition, these patients had a higher symptom burden and higher levels of cancer-specific stress. CONCLUSIONS: Clinicians can use the information provided in this study to identify high-risk patients and develop individualized interventions.

Published
2024

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