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3. Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy

7. Severe mitochondrial encephalomyopathy caused by de novo variants in OPA1 gene.

8. The ataxia-linked E1081Q mutation affects the sub-plasma membrane Ca2+-microdomains by tuning PMCA3 activity

9. De Novo DNM1L Mutation in a Patient with Encephalopathy, Cardiomyopathy and Fatal Non-Epileptic Paroxysmal Refractory Vomiting.

12. Case report: A safeguard in the sea of variants of uncertain significance: a case study on child with high risk neuroblastoma and acute myeloid leukemia

17. Inflammatory profile in mitochondrial diseases: A cohort study

24. Novel mutations in IBA57 are associated with leukodystrophy and variable clinical phenotypes

25. AFG3L2 Biallelic Mutation: Clinical Heterogeneity in Two Italian Patients

26. A20 Reduced levels of the glucose transporter glut-1 in brain striatum and periphery reveals clues to specific pathomechanisms in childhood-onset Huntington disease

27. Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement

28. Biallelic SQSTM1 mutations in early-onset, variably progressive neurodegeneration

29. Succinate-CoA ligase deficiency due to mutations in SUCLA2 and SUCLG1: phenotype and genotype correlations in 71 patients

30. Bi-allelic LETM1 variants perturb mitochondrial ion homeostasis leading to a clinical spectrum with predominant nervous system involvement

31. Novel TOP3A Variant Associated With Mitochondrial Disease: Expanding the Clinical Spectrum of Topoisomerase III Alpha-Related Diseases

33. SHP2 's gain‐of‐function in Werner syndrome causes childhood disease onset likely resulting from negative genetic interaction

34. A novel homozygous variant inCOX5Acauses an attenuated phenotype with failure to thrive, lactic acidosis, hypoglycemia and short stature

35. Spinal cord involvement in Kearns-Sayre syndrome: a neuroimaging study

38. LYRM7 mutations cause a multifocal cavitating leukoencephalopathy with distinct MRI appearance

40. Hyperactive HRAS dysregulates energetic metabolism in fibroblasts from patients with Costello syndrome via enhanced production of reactive oxidizing species

41. F54 ‘Spazio huntington – a place for children’: an Italian observational, multicentre, program to detect pediatric huntington disease cases

45. The ataxia-linked E1081Q mutation affects the sub-plasma membrane Ca2+-microdomains by tuning PMCA3 activity.

47. Pontocerebellar hypoplasia type 6 caused by mutations in RARS2: definition of the clinical spectrum and molecular findings in five patients

48. SPEN haploinsufficiency causes a neurodevelopmental disorder overlapping proximal 1p36 deletion syndrome with an episignature of X chromosomes in females

50. Understanding pyrroline-5-carboxylate synthetase deficiency: clinical, molecular, functional, and expression studies, structure-based analysis, and novel therapy with arginine

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