Search

Your search keyword '"Carrel, S."' showing total 345 results
Start Over Author "Carrel, S."
345 results on '"Carrel, S."'

4. Transplantation of a Human Mammary Carcinoma Cell Line (BT 20) Into Nude Mice

Author

Ozzello, L., Sordat, B., Merenda, C., Carrel, S., Hurlimann, J., Mach, J. P., Ozzello, L., Sordat, B., Merenda, C., Carrel, S., Hurlimann, J., and Mach, J. P.

Abstract

Cell suspensions of a human mammary carcinoma cell line (BT 20), when injected subcutaneously into nude athymic mice (BALB/c Nu/Nu), produced tumor nodules at the injection site. Subsequent serial transplantations also gave rise to neoplastic nodules after latency periods averaging 3 weeks. The nodules displayed morphologic and functional characteristics comparable to those of the original tumor cells. Metastases, however, were not observed in any of the tumor-bearing mice

Published
2017

8. Melanoma Immunology

Author

Bystryn, J. C., Kokoschka, E. M., Bröcker, E. B., Reisfeld, R., Ruiter, D. J., Vennegoor, C., Ferrone, S., Cesarini, J., Gaudry, H., Carrel, S., Giuffrè, L., Accolla, R., Isler, P., Zwadlo, G., Macher, E., Sorg, C., Luger, T. A., Köck, A., Vetterlein, M., Micksche, M., Gigli, I., Martin, D. E., Müller-Eberhard, H. J., Orfanos, Constantin E., editor, Stadler, Rudolf, editor, and Gollnick, Harald, editor

Published
1988
Full Text
View/download PDF

11. Expression and Characterization of Leucocyte Antigens

Author

Allen, R., Ferrone, S., Hoch, J., Bankhurst, A., Spellmann, J., Burmester, G. R., Dimitriu-Bona, A., Gregersen, P., Waters, S. J., Winchester, R. J., Burrone, O. R., Calabi, F., Gilmore, D., Wright, B., Milstein, C., Clark, E., Martin, P., Hansen, J., Ledbetter, J., de Leij, L., Poppema, S., The, T. H., De Vries, J. E., Vaessen, R., Janssens, P., Tan, B., Heiman, A., Figdor, C. G., Dörken, B., Pfreundschuh, M., Moldenhauer, G., Schwarz, E., Hämmerling, G., Frisman, D., Baird, S., Gazit, E., Gothelf, Y., Gil, R., Orgad, S., Yunis, E. J., Girardet, Ch., Heumann, D., Mach, J.-P., von Fliedner, V., Carrel, S., Goyert, S. M., Silver, J., Hogg, N., Hokland, P., Schlossman, S. F., Ritz, J., Kalil, J., Abita, J. P., Chomienne, C., Poirier, O., Besluau, D., Dastot, H., Reboul, M., Fellous, M., Colombani, J., Kater, L., Brekelmans, P., Daemen, T., Schuurman, H. J., Katz, F., Povey, S., Stanley, K., Schneider, C., Greaves, M., Lemonnier, F. A., Le Bouteiller, P. P., Malissen, B., Golstein, P., Malissen, M., Mishal, Z., Caillol, D. H., Jordan, B. R., Kourilsky, F., Lennert, K., Stein, H., Miiller-Hermelink, H. K., Vollenweider, R., Karol, R. A., Eng, J., Dennison, D., Faris, E., Marcus, D. M., Piatier-Tonneau, D., Boyer, B., Debre, P., Charron, D., Reuben, J. M., Hersh, E. M., Mansell, P. W. A., Newell, G., Rios, A., Rumpold, H., Kraft, D., Förster, O., Schulz, T. F., Alsenz, J., Scheiner, O., Lambris, J., Dierich, M. P., Van Laarhoven, J. P. R. M., Broekhuizen, R., Spierenburg, G. Th., De Bruyn, C. H. M. M., Solbach, W., Röllinghoff, M., Wagner, H., Szer, I. S., Irani, A., Tax, W. J. M., Janossy, G., Jonker, M., Willems, R., Leeuwenberg, J., Capel, P. J. A., Koene, R. A. P., Leeuwenberg, H. F. M., Willems, H. M., Tetteroo, P. A. T., Visser, F., Landsdorp, P., von dem Borne, A. E. G. Kr., Thompson, J. S., Goeken, N. E., Brown, S. A., Rhoades, J. R., Yamamoto, K., Nakauchi, H., Karasuyama, H., Kitamura, K., Tanimoto, K., Okumura, K., Bernard, Alain, editor, Boumsell, Laurence, editor, Dausset, Jean, editor, Milstein, César, editor, and Schlossman, Stuart F., editor

Published
1984
Full Text
View/download PDF

12. Leucocyte Malignancies

Author

Andrews, R. G., Bernstein, I. D., Torok-Storb, B., Bell, C. G., Biberfeld, P., Christensson, B., Öst, Å., Hast, R., Skoog, L., Andreason, R., Olsson, L., Lagerlöf, B., Reizenstein, P., Boucheix, C., Perrot, J. Y., Mirshahi, M., Fournier, N., Billard, M., Giannoni, F., Bernadou, A., Rosenfeld, C., Chiao, J. W., Wang, C. Y., Del Giacco, G. S., Cengiarotti, L., Di Tucci, A., Broccia, G., Corda, G., Mathieu, A., Indiveri, F., Locci, F., Mantovani, G., Detrick-Hooks, B., Boumsell, L., Bernard, A., Hooks, J. J., Divine, M., Farcet, J. P., Gourdin, M. F., Vasconcelos, A., Tabilio, A., Andre, C., Bouguet, J., Reyes, F., Fontan, S., Zabay, J. M., Garcia, M. C., Pascual-Salcedo, D., Campos, A., de la Concha, E. G., Gordon, J., Åman, P., Mellstedt, H., Klein, G., Habeshaw, J. A., Herrmann, F., Sieber, G., Rühl, H., Lebacq, A. M., Ravoet, A. M., Bazin, H., De Bruyere, M., Rodhain, J., Sokal, G., Losa, G., Maestroni, G., Lucivero, G., Antonaci, S., Stomeo, C., Bonomo, L., Magaud, J. P., Brochier, J., Vu Van, H., El Ansary, M., Gentilhomme, O., Bryon, P. A., Mathé, G., Minowada, J., Ogier, C., Ginsbourg, M., Goutner, A., Knapp, W., Canon, C., Melief, C. J. M., Miedema, F., Rümke, H. C., ten Berge, R. J. M., Terpstra, F. G., v.d. Borne, A. E. G. Kr., Willemze, R., v. Vloten, W., Miljkovic, A. K., Isakovic, K., Jankovic, B. D., Peng, R., Knowles, D. M., Bushkin, Y., Petrányi, G. G., Busch, G., Milford, E., Todd, R., Griffin, J., Reinherz, E., Terhorst, C., Schlossman, St., Carpenter, Ch., Richard, Y., Demeocq, F., Schwarting, R., Thoen, J., Førre, Ø. T., von Fliedner, V., Carrel, S., Heumann, D., Zaech, P., Sekaly, R. P., Girardet, Ch., Mach, J. P., Azzo, W., Worman, C., Mills, K., Brooks, D., Hogg, N., Zola, H., Beverly, P., Cawley, J., Bernard, Alain, editor, Boumsell, Laurence, editor, Dausset, Jean, editor, Milstein, César, editor, and Schlossman, Stuart F., editor

Published
1984
Full Text
View/download PDF

13. Brain Tumor-Associated Antigens

Author

Carrel S, de Tribolet N, and Mach Jp

Subjects
Text mining, Antigen, business.industry, Brain tumor, medicine, Cancer research, Biology, medicine.disease, business
Published
2015
Full Text
View/download PDF

17. Stimulation of human T cells by streptococcal 'superantigen' erythrogenic toxins (scarlet fever toxins)

Author

Ma, Braun, Gerlach D, Udo Hartwig, Jh, Ozegowski, Romagné F, Carrel S, Köhler W, and Fleischer B

Subjects
Antigens, Bacterial, Scarlet Fever, Streptococcus pyogenes, Receptors, Antigen, T-Cell, alpha-beta, T-Lymphocytes, Immunology, Histocompatibility Antigens Class II, Immunoglobulin Variable Region, Exotoxins, Membrane Proteins, Lymphocyte Activation, Bacterial Proteins, Humans, Immunology and Allergy
Abstract

The pyrogenic (erythrogenic) exotoxins A and C (SPEA and SPEC) of Streptococcus pyogenes belong to the family of mitogenic toxins of which the staphylococcal enterotoxins are the prototypes. The erythrogenic toxin B (SPEB) is a proteinase precursor. All SPE have been reported to be superantigens. Here we have analyzed the human T cell response to these toxins. We used highly purified preparations of SPEA, SPEB, and SPEC from different S. pyogenes strains. These toxins were apparently homogenous in SDS-PAGE, IEF, and HPLC. In addition, recombinant SPEA and SPEC were produced in Escherichia coli. In cultures of PBMC, all three toxins expanded preferentially a fraction of T cells. Using mAb against V beta 2, -5, -6, -8, and -12, we investigated the phenotype of the stimulated cells. Natural SPEA, SPEB, and SPEC strongly stimulated V beta 8+ T cells, whereas recombinant SPEA and SPEC did not. Both natural and recombinant SPEA stimulated V beta 12+ cells and both natural and recombinant SPEC stimulated V beta 2+ cells. In accordance with these findings, a human V beta 8+ line responded to all three toxins derived from S. pyogenes but not to the recombinant proteins. An antiserum against natural SPEC neutralized specifically the V beta 2-stimulating activity of SPEC and the V beta 8-stimulating activity of all three toxins, but had no effect on the response to other superantigens. This shows that trace amounts of a potent novel V beta 8-stimulating activity not identical to SPEA and SPEC are responsible for the stimulation of V beta 8+ T cells by natural SPEA and SPEC reported previously. In a preliminary screening of S. pyogenes strains from patients, we found that this novel superantigen appears to be more widely distributed than SPEA and SPEC. Furthermore, we present evidence that also the superantigenic properties of SPEB are due to contaminations with this V beta 8 stimulator. The response to SPEB usually required 1000 times higher concentrations than to SPEA or SPEC. Antisera to SPEC but not to SPEB inhibited the response of PBMC and V beta 8+ Jurkat cells to SPEB. Furthermore, more stringent purification of SPEB yielded SPEB preparations devoid of mitogenic activity. These results indicate that the mitogenicity that is commonly attributed to SPEB is due to minute contaminations of the V beta 8 stimulator. These results raise two important caveats for the work with these highly potent T cell mitogens.(ABSTRACT TRUNCATED AT 400 WORDS)

Published
1993
Full Text
View/download PDF

27. Human melanoma cells express a functional interleukin-2 receptor

Author

Plaisance, S., primary, Rubinstein, E., additional, Alileche, A., additional, Han, D. S., additional, Sahraoui, Y., additional, Mingari, M. C., additional, Bellomo, R., additional, Rimoldi, D., additional, Colombo, M. P., additional, Jasmin, C., additional, Carrel, S., additional, and Azzarone, B., additional

Published
1993
Full Text
View/download PDF

42. Regulation of clonal growth by anti-T-cell receptor antibody-directed lysis.

Author

De Berardinis, P., Londei, M., Carrel, S., and Feldmann, M.

Subjects
T cells, IMMUNOGLOBULINS, LYMPHOCYTES, MONOCLONAL antibodies, CELL receptors, CLONE cells
Abstract

CD4 and CD8 T-cell clones were generated using the Mx9 monoclonal antibody (mAb), which recognizes the Vβ8 T-cell receptor (TcR) gene family. The interaction of these clones with the Mx9 antibody was analysed and all were found to be specifically stimulated to proliferate by plastic- adherent Mx9. In the presence of Mx9 or its F(ab')2 fragment, CD8+Mx9+ clones were capable of specifically lysing the CD4 + Mx9-T-cell clones. No lysis was seen of Mx9+ T-cells, or in the absence of the antibody. Conversely CD4 Mx9+ cells did not have lytic function. These results indicate that cross-linking of T cells via their antigen-specific receptors may initiate a unidirectional killing. Unlike previously reported lytic systems involving anti-TcR antibodies (e.g. anti-CD3), these results suggest that this mechanism may have an important physiological role in immune regulation. Antis idiotypic antibodies have been shown to recognize T-cell receptors. These may exert profound immunosuppressive effects by inducing the lysis of the helper cells or B cells. [ABSTRACT FROM AUTHOR]

Published
1988

43. Neoplastic meningitis in malignant melanoma: diagnosis with monoclonal antibodies.

Author

Moseley, R P, Davies, A G, Bourne, S P, Popham, C, Carrel, S, Monro, P, and Coakham, H B

Abstract

Six patients with neoplastic melanomatous meningitis were studied. The diagnosis of this complication of malignant disease rests on the demonstration of malignant cells within the CSF. The addition of monoclonal antibody immunocytology to conventional techniques significantly improved the diagnostic sensitivity of CSF cytology, allowing for earlier and therefore more effective palliative treatment. [ABSTRACT FROM AUTHOR]

Published
1989

Catalog

Books, media, physical & digital resources
See catalog results