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8. 1885P Pexa-vec (thymidine kinase-deactivated vaccinia virus plus GM-CSF) in combination with cemiplimab (REGN2810; ANTI-PD-1) for metastatic or unresectable renal cell carcinoma REN026: Results from a phase II study

Author

Rha, S.Y., Bae, W.K., Kim, C., Oh, S.Y., Lee, H.W., Park, K., Mar, N., Kichenadasse, G., Ha, H.K., Pachynski, R., Park, I., Park, K.H., Kim, S.H., Folefac, E., Mathias, M.D., Seebach, F., Ma, S., Carranza, L., Beom, S-H., and Merchan, J.R.

Published
2023
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11. ACE16k: the third generation of mixed-signal SIMD-CNN ACE chips toward VSoCs

Author

Rodriguez-Vazquez, Angel, Linan-Cembrano, Gustavo, Carranza, L., Roca-Moreno, Elisenda, Carmona-Galan, Ricardo, Jimenez-Garrido, Francisco, Dominguez-Castro, Rafael, and Meana, Servando Espejo

Subjects
Business, Computers and office automation industries, Electronics, Electronics and electrical industries
Abstract

Today, with 0.18-[micro]m technologies mature and stable enough for mixed-signal design with a large variety of CMOS compatible optical sensors available and with 0.09-[micro]m technologies knocking at the door of designers, we can face the design of integrated systems, instead of just integrated circuits. In fact, significant progress has been made in the last few years toward the realization of vision systems on chips (VSoCs). Such VSoCs are eventually targeted to integrate within a semiconductor substrate the functions of optical sensing, image processing in space and time, high-level processing, and the control of actuators. The consecutive generations of ACE chips define a roadmap toward flexible VSoCs. These chips consist of arrays of mixed-signal processing elements (PEs) which operate in accordance with single instruction multiple data (SIMD) computing architectures and exhibit the functional features of CNN Universal Machines. They have been conceived to cover the early stages of the visual processing path in a fully-parallel manner, and hence more efficiently than DSP-based systems. Across the different generations, different improvements and modifications have been made looking to converge with the newest discoveries of neurobiologists regarding the behavior of natural retinas. This paper presents considerations pertaining to the design of a member of the third generation of ACE chips, namely to the so-called ACE16k chip. This chip, designed in a 0.35-[micro]m standard CMOS technology, contains about 3.75 million transistors and exhibits peak computing figures of 330 GOPS, 3.6 GOPS/[mm.sup.2] and 82.5 GOPS/W. Each PE in the array contains a reconfigurable computing kernel capable of calculating linear convolutions on 3 x 3 neighborhoods in less than 1.5 [micro]s, imagewise Boolean combinations in less than 200 ns, imagewise arithmetic operations in about 5 [micro]s, and CNN-like temporal evolutions with a time constant of about 0.5 [micro]s. Unfortunately, the many ideas underlying the design of this chip cannot be covered in a single paper; hence, this paper is focused on, first, placing the ACE16k in the ACE chip roadmap and, then, discussing the most significant modifications of ACE16K versus its predecessors in the family. Index Terms--Analog programmable very large-scale integration (VLSI), early vision chips, silicon retinas.

Published
2004

13. Memoria involuntaria y acontecimiento en un relato de Julio Cortázar

Author

Inzaurralde, G., Vázquez, M.C., Rodríguez, Carranza L., Soto, van der Plas C., Vázquez, M.C., Rodríguez, Carranza L., and Soto, van der Plas C.

Abstract

Image and realism are recurrent topics in aesthetic, philosophic and political debates every time there is a concern about the contemporaneous, since their origins as well as their overlapped destinies share a common questioning of the present. Lukác’s distinction between narration and description can be read as the canonical formulation of an opposition—the image is the strategy of description and seeks the immediate seizure of the present, whereas the realist fiction orders the past, explains it and gives it an intelligible social coherence. The image is seen and the realist fiction sees, exercising a classificatory biopolitic.

Published
2014

24. [Ocular tuberculosis]

Author

M Elena, De Benedetti Z, Bárbara, Carranza L, Eduardo, Gotuzzo H, and Isaías, Rolando C

Subjects
Antitubercular Agents, Humans, Drug Therapy, Combination, Tuberculosis, Ocular
Abstract

Tuberculosis (TB) is considered a public health problem in several countries. This disease is classified as either pulmonary or extrapulmonary. Within the extrapulmonary disease, ocular involvement is uncommon but it is important to recognize it because its incidence has been reported up to 1%. Ocular TB cases can be divided in primary and secondary. These manifestations can be caused by an active infection that invades the eye or by an immunologic reaction of delayed hypersensitivity in absence of the infectious agent. The most common clinical presentations are: chronic anterior uveitis, choroiditis and sclerokeratitis. Despite the existence of highly sensitive molecular diagnostic techniques, the diagnosis of ocular tuberculosis continues to be presumptive, based upon clinical presentation, systemic evaluation and response to treatment. For the treatment we use four drugs during a two month period (isoniazid, rifampin, pyrazinamide and ethambutol) and two drugs for four additional months.

Published
2007

25. Tuberculosis ocular

Author

De Benedetti Z,M. Elena, Carranza L,Bárbara, Gotuzzo H,Eduardo, and Rolando C,Isaías

Subjects
Infectious Diseases, tubérculos coroideos, uveitis, Public Health, Environmental and Occupational Health, Tuberculosis ocular, manifestaciones oculares, diagnóstico
Abstract

La tuberculosis (TBC) es considerada un problema de salud pública en varios países del mundo. Esta enfermedad se clasifica en pulmonar y extra pulmonar. Dentro de la forma extra pulmonar, el compromiso ocular es poco común, pero es importante conocerlo ya que su incidencia puede llegar hasta 1%. Los casos de TBC ocular se dividen en primarios y secundarios. Las manifestaciones oculares pueden ser causadas por una infección activa que invade el ojo o por una reacción inmunológica de hipersensibilidad retardada, en ausencia del agente infeccioso. Las presentaciones más comunes son: uveítis anterior crónica, coroiditis y esclero-queratitis. A pesar de la existencia de herramientas moleculares altamente sensibles, el diagnóstico de TBC ocular continúa siendo presuntivo, basándose en la presentación clínica, evaluación sistémica y la respuesta terapéutica. Para el tratamiento se utilizan cuatro fármacos por dos meses (isoniacida, rifampicina, pirazinamida y etambutol) y dos fármacos por cuatro meses adicionales

Published
2007

26. Tuberculosis ocular

Author

De Benedetti Z, M. Elena, Carranza L, Bárbara, Gotuzzo H, Eduardo, and Rolando C, Isaías

Subjects
diagnosis, tubérculos coroideos, uveitis, Tuberculosis ocular, ocular tuberculosis, choroidal tubercles, manifestaciones oculares, ocular manifestations, diagnóstico
Abstract

La tuberculosis (TBC) es considerada un problema de salud pública en varios países del mundo. Esta enfermedad se clasifica en pulmonar y extra pulmonar. Dentro de la forma extra pulmonar, el compromiso ocular es poco común, pero es importante conocerlo ya que su incidencia puede llegar hasta 1%. Los casos de TBC ocular se dividen en primarios y secundarios. Las manifestaciones oculares pueden ser causadas por una infección activa que invade el ojo o por una reacción inmunológica de hipersensibilidad retardada, en ausencia del agente infeccioso. Las presentaciones más comunes son: uveítis anterior crónica, coroiditis y esclero-queratitis. A pesar de la existencia de herramientas moleculares altamente sensibles, el diagnóstico de TBC ocular continúa siendo presuntivo, basándose en la presentación clínica, evaluación sistémica y la respuesta terapéutica. Para el tratamiento se utilizan cuatro fármacos por dos meses (isoniacida, rifampicina, pirazinamida y etambutol) y dos fármacos por cuatro meses adicionales Tuberculosis (TB) is considered a public health problem in several countries. This disease is classified as either pulmonary or extrapulmonary. Within the extrapulmonary disease, ocular involvement is uncommon but it is important to recognize it because its incidence has been reported up to 1%. Ocular TB cases can be divided in primary and secondary. These manifestations can be caused by an active infection that invades the eye or by an immunologic reaction of delayed hypersensitivity in absence of the infectious agent. The most common clinical presentations are: chronic anterior uveitis, choroiditis and sclerokeratitis. Despite the existence of highly sensitive molecular diagnostic techniques, the diagnosis of ocular tuberculosis continues to be presumptive, based upon clinical presentation, systemic evaluation and response to treatment. For the treatment we use four drugs during a two month period (isoniazid, rifampin, pyrazinamide and ethambutol) and two drugs for four additional months

Published
2007

27. Use of the fractal dimension for porosity modification in aluminum foams manufactured using space holder particles

Author

Reyes Christian C., Béjar Luis, Pérez Luis, Aguilar Claudio, Carranza Juan C., Carranza Luis E., and Alfonso Ismeli

Subjects
metal foams, aluminum alloys, fractals, young modulus, advanced materials, Mechanics of engineering. Applied mechanics, TA349-359
Abstract

The effect of space holder particles (SHP) fractal distribution on the porosity of aluminum foams manufactured by infiltration is studied in the present work. Physical models were used to estimate aluminum foam porosity, simulating SHP distribution for bimodal mixtures with different particle sizes and relative quantities. Results of these models were compared with mathematical models and the results obtained for experimental aluminum foams manufactured using a 332 Al-alloy base material and NaCl grains as SHP. Experimental foam structural characterization was carried out using image analysis to obtain porosity, density, wall thickness and fractal dimension, while mechanical characterization focused on the compressive Young modulus. Results show that it was possible to manufacture foams with different fractal porosities and a wide variety of unit cells, reaching a maximum of ∼ 68%. It was also found that pore wall thicknesses significantly decreased with the increase in the fine particles fraction. Besides, all the models presented a peak with a maximum porosity, whose values increased and shifted to low fine particles fraction with the increase in the sizes ratio. This behavior was also observed for the experimental foams with low particle size ratio. Nevertheless, for higher size ratios porosity showed an irregular behavior attributed to the mixing process.

Published
2021
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31. SEE characterization of the AMS 0.35 μm CMOS technology

Author

Ramos, J., primary, Arias, A., additional, Mora, J. M., additional, Munoz, M., additional, Ragel, A., additional, Pinero, B., additional, Ceballos, J., additional, Carranza, L., additional, Sordo, S., additional, Lagos, M. A., additional, and Espejo, S., additional

Published
2013
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32. Phase II trial with navelbine + cisplatin + etoposide in the treatment of inoperable non-small cell lung carcinoma

Author

Richardet, Eduardo Arnoldo, Carranza, L., Uribe, A., Tolocka, H., Cresta, Cecilia, Uribe, E., and Uribe, M.

Subjects
R Medicina (General)
Abstract

40 patients with advanced non-small cell lung cancer not previously treated were included in a study at phase II with vinorelbine 20 mg/Sq.m days 1 and 8, etoposide 60 mg/sq.m days 1-3 and cisplatin 75 mg/sq.m day 1 each 28 days for 6 cycles. There were 31 men and 9 women, being the average age of 54 years, with "performance Status" grade 0-2. All of them could be evaluated for toxicity and 31 for responsiveness. 10 patients were in stage IIIb and 21 at stage IV. 42% of objective responses were obtained and an overall survival of 9 months, which justifies further studies., Fil: Richardet, Eduardo Arnoldo. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Carranza, L. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Uribe, A. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Tolocka, H. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Cresta, Cecilia. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Uribe, E. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Uribe, M. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina

Published
1995

33. Evolution of patients with synchronic brain metastasis of non-small cell lung cancer [Evolución de pacientes con metástasis cerebral sincrónica de carcinoma de pulmón no células pequeñas]

Author

Richardet, Eduardo Arnoldo, Carranza, L., Bella, S., Richardet, M., García Cocco, V., Melchior, A., Uribe Echeverría, A., Richardet, Eduardo Arnoldo, Carranza, L., Bella, S., Richardet, M., García Cocco, V., Melchior, A., and Uribe Echeverría, A.

Abstract

Objective: to determine and compare median (MS) and overall (OS) survivals of a group of patients with NSCLC and synchronic brain metastasis treated with multimodal therapy (MM) -neurosurgery + radio-chemotherapy-bimodal therapy (BM) -radio-chemotherapy- or radiotherapy alone (RT) Patients and methods: pts. with simultaneous diagnosis of NSCLC and brain metastasis were included. They were evaluated with toraco-abdominal CT scan, bone scintigraphy and brain CT scan. The work-up of pts. eligible for neurosurgery included a brain MRL Those pts. with one brain metastasis and adequate local (candidates to surgery) tumors were treated with MM. Pts. with multiple brain metastasis or inadequate local tumors were treated with BM or RT. Neurosurgery was adequated to metastasis location. Radiotherapy consisted in holocraneal 5,040 cGys and there were used two chemotherapy schemes (cisplatin 75 mgs-sqm on day 1, vinorelbine 20 mgs-sqm on days 1 and 8 and etoposide 60 mgs-sqm on days 1,2 and 3 or carboplatin AUC 6 and paclitaxel 200 mgs-sqm on day 1). The association of radio-chemotherapy was developed concurrently with the first cycle. MS and 1 year OS with Kaplan Meier method were determined. Results: from 388 patients with NSCLC treated between 1990 and 1999, 31 were included in the present study. Histology: adeno: 14 pts., squamous: 13 pts. Undifferenciated: 2 pts., Large Cells: 1 pt. Median follow-up for the entire group was 9.8 months. 16/31 pts. had one brain metastasis. 6 were treated with MM and 10 with BM. For pts. with MM, median age was 52.16 (r: 39-54) and MS and OS were 11.66 months and 12% respectively. For pts. with BM, median age was 64.4 (r: 43-78) and MS and OS were 2.8 months and 0% respectively. 15/31 pts. had multiple brain metastasis. 12 pts. received BM and 3 RT. For the first group, median age was 53 (r: 32-71), OS and MS were 4 months and 0% respectively and for the second median age was 54 (r: 38-63), OS and MS were 2.33 months and 0% respectively. One, Fil: Richardet, Eduardo Arnoldo. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Carranza, L. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Bella, S. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Richardet, M. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: García Cocco, V. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Melchior, A. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina, Fil: Uribe Echeverría, A. Universidad Católica de Córdoba. Facultad de Ciencias de la Salud; Argentina

Published
2003

35. Tipos climáticos y vegetación leñosa del sector tirrénico del Lazio centro-septentrional (Pcias. de Roma y Viterbo, Italia)

Author

Biasi, C., Acosta, A., Tilia, A., Filesi, L., Michetti, L., and Carranza, L.

Subjects
Italia centrale, bioclima, bosques, formaciones vegetales, análisis de componentes principales
Abstract

Submitted by Margarida Galamba (galamba@isa.utl.pt) on 2018-10-17T09:40:47Z No. of bitstreams: 1 REP-ANAIS-34-20093078506.pdf: 107859 bytes, checksum: f82cd0a4fa505bced065b2a9e3c73a95 (MD5) Made available in DSpace on 2018-10-17T09:40:47Z (GMT). No. of bitstreams: 1 REP-ANAIS-34-20093078506.pdf: 107859 bytes, checksum: f82cd0a4fa505bced065b2a9e3c73a95 (MD5) Previous issue date: 1994 info:eu-repo/semantics/publishedVersion

Published
1994

41. Elias Rivera

Author

Carranza, L. E.

Subjects
Elias Rivera (Book) -- Book reviews, Books -- Book reviews, Library and information science, Literature/writing
Published
2007

42. Felix Gonzalez-Torres

Author

Carranza, L. E.

Subjects
Felix Gonzalez-Torres (Book) -- Book reviews, Books -- Book reviews, Library and information science, Literature/writing
Published
2007

43. Gego: Between Transparency and the Invisible

Author

Carranza, L. E.

Subjects
Gego: Between Transparency and the Invisible (Book) -- Book reviews, Books -- Book reviews, Library and information science, Literature/writing
Published
2006

45. Latin American and Caribbean Art: MoMa at El Museo

Author

Carranza, L. E.

Subjects
Latin American and Caribbean Art: MoMa at El Museo (Book) -- Book reviews, Books -- Book reviews, Library and information science, Literature/writing
Published
2004

48. The Road to Aztlan: Art from a Mythic Homeland

Author

Carranza, L. E.

Subjects
The Road to Aztlan: Art from a Mythic Homeland (Book) -- Book reviews, Books -- Book reviews, Library and information science, Literature/writing
Published
2002

49. Insect-vision inspired collision warning vision processor for automobiles.

Author

Linan-Cembrano, G., Carranza, L., Rind, C., Zarandy, A., Soininen, M., and Rodriguez-Vazquez, A.

Abstract

Vision is expected to play important roles for car safety enhancement. Imaging systems can be used to enlarging the vision field of the driver. For instance capturing and displaying views of hidden areas around the car which the driver can analyze for safer decision-making. Vision systems go a step further. They can autonomously analyze the visual information, identify dangerous situations and prompt the delivery of warning signals. For instance in case of road lane departure, if an overtaking car is in the blind spot, if an object is approaching within collision course, etc. Processing capabilities are also needed for applications viewing the car interior such as "intelligent airbag systems" that base deployment decisions on passenger features. On-line processing of visual information for car safety involves multiple sensors and views, huge amount of data per view and large frame rates. The associated computational load may be prohibitive for conventional processing architectures. Dedicated systems with embedded local processing capabilities may be needed to confront the challenges. This paper describes a dedicated sensory-processing architecture for collision warning which is inspired by insect vision. Particularly, the paper relies on the exploitation of the knowledge about the behavior of Locusta Migra- toria to develop dedicated chips and systems which are integrated into model cars as well as into a commercial car (Volvo XC90) and tested to deliver collision warnings in real traffic scenarios. [ABSTRACT FROM PUBLISHER]

Published
2008
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