35 results on '"Carpinelli, Patrizia"'
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2. Supplementary Fig. S1 from PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer
3. Supplementary Table S1 from PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer
4. Data from Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor PHA-739358
5. Supplementary Table 1 from Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor PHA-739358
6. Phase I dose escalation study of NMS-1286937, an orally available Polo-Like Kinase 1 inhibitor, in patients with advanced or metastatic solid tumors
7. Aurora Kinases and Their Inhibitors: More Than One Target and One Drug
8. Identification of Myb-binding Protein 1A (MYBBP1A) as a Novel Substrate for Aurora B Kinase
9. Thieno[3,2- c]pyrazoles: A novel class of Aurora inhibitors with favorable antitumor activity
10. PHA-680626 Is an Effective Inhibitor of the Interaction between Aurora-A and N-Myc
11. A Focused Small-Molecule Screen Identifies PHA-680626 as an Amphosteric Inhibitor Disrupting the Interaction between Aurora-A and N-Myc
12. Characterization of the BUD31 gene of Saccharomyces cerevisiae
13. Cloning and overexpression in Escherichia coli of the genes encoding NAD-dependent alcohol dehydrogenase from two Sulfolobus species
14. Abstract 3795: Novel and selective MELK kinase inhibitors active in breast cancer cell lines
15. Combined cisplatin and aurora inhibitor treatment increase neuroblastoma cell death but surviving cells overproduce BDNF
16. Phase I dose escalation study of NMS-1286937, an orally available Polo-Like Kinase 1 inhibitor, in patients with advanced or metastatic solid tumors.
17. Structural Insight into Maternal Embryonic Leucine Zipper Kinase (MELK) Conformation and Inhibition toward Structure-Based Drug Design
18. Transcriptional analysis of the Aurora inhibitor Danusertib leading to biomarker identification in TP53 wild type cells
19. GDF15 as a Novel Biomarker for Monitoring Danusertib Activity
20. Phase I Pharmacokinetic and Pharmacodynamic Study of the Aurora Kinase Inhibitor Danusertib in Patients With Advanced or Metastatic Solid Tumors
21. Aurora kinase inhibitors: identification and preclinical validation of their biomarkers
22. PHA-739358, a potent inhibitor of Aurora kinases with a selective target inhibition profile relevant to cancer
23. Crystal Structure of the T315I Abl Mutant in Complex with the Aurora Kinases Inhibitor PHA-739358
24. 1,4,5,6-Tetrahydropyrrolo[3,4-c]pyrazoles: Identification of a Potent Aurora Kinase Inhibitor with a Favorable Antitumor Kinase Inhibition Profile
25. PHA-680632, a Novel Aurora Kinase Inhibitor with Potent Antitumoral Activity
26. Potent and Selective Aurora Inhibitors Identified by the Expansion of a Novel Scaffold for Protein Kinase Inhibition
27. Aurora Kinases and Their Inhibitors: More Than One Target and One Drug.
28. Analysis of the molecular species generated by mdm2 gene amplification in liposarcomas
29. Suramin modulates cellular levels of hepatocyte growth factor receptor by inducing shedding of a soluble form
30. Antiproliferative effects and DNA hypomethylation by 5-aza-2′-deoxycytidine in human neuroblastoma cell lines
31. Five-coordinate platinum(II) complexes containing substituted olefins: synthesis and cytostatic activity
32. Aurora kinase inhibitors: identification and preclinical validation of their biomarkers
33. Combined cisplatin and aurora inhibitor treatment increase neuroblastoma cell death but surviving cells overproduce BDNF
34. A phase I study of danusertib (PHA-739358) in adult patients with accelerated or blastic phase chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia resistant or intolerant to imatinib and/or other second generation c-ABL therapy.
35. Is there a future for Aurora kinase inhibitors for anticancer therapy?
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