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2. Artificial Intelligence to Assist in Exclusion of Coronary Atherosclerosis during CCTA Evaluation of Chest-Pain in the Emergency Department: Preparing an Application for Real-World Use

Author

White, Richard D., Erdal, Barbaros S., Demirer, Mutlu, Gupta, Vikash, Bigelow, Matthew T., Dikici, Engin, Candemir, Sema, Galizia, Mauricio S., Carpenter, Jessica L., Donnell, Thomas P. O, Halabi, Abdul H., and Prevedello, Luciano M.

Subjects
Electrical Engineering and Systems Science - Image and Video Processing, Computer Science - Computer Vision and Pattern Recognition, Physics - Medical Physics, I.5.4, I.5.2, I.2.10
Abstract

Coronary Computed Tomography Angiography (CCTA) evaluation of chest-pain patients in an Emergency Department (ED) is considered appropriate. While a negative CCTA interpretation supports direct patient discharge from an ED, labor-intensive analyses are required, with accuracy in jeopardy from distractions. We describe the development of an Artificial Intelligence (AI) algorithm and workflow for assisting interpreting physicians in CCTA screening for the absence of coronary atherosclerosis. The two-phase approach consisted of (1) Phase 1 - focused on the development and preliminary testing of an algorithm for vessel-centerline extraction classification in a balanced study population (n = 500 with 50% disease prevalence) derived by retrospective random case selection; and (2) Phase 2 - concerned with simulated-clinical Trialing of the developed algorithm on a per-case basis in a more real-world study population (n = 100 with 28% disease prevalence) from an ED chest-pain series. This allowed pre-deployment evaluation of the AI-based CCTA screening application which provides a vessel-by-vessel graphic display of algorithm inference results integrated into a clinically capable viewer. Algorithm performance evaluation used Area Under the Receiver-Operating-Characteristic Curve (AUC-ROC); confusion matrices reflected ground-truth vs AI determinations. The vessel-based algorithm demonstrated strong performance with AUC-ROC = 0.96. In both Phase 1 and Phase 2, independent of disease prevalence differences, negative predictive values at the case level were very high at 95%. The rate of completion of the algorithm workflow process (96% with inference results in 55-80 seconds) in Phase 2 depended on adequate image quality. There is potential for this AI application to assist in CCTA interpretation to help extricate atherosclerosis from chest-pain presentations., Comment: 13 pages, 9 figures

Published
2020

3. Language and developmental plasticity after perinatal stroke

Author

Newport, Elissa L., Seydell-Greenwald, Anna, Landau, Barbara, Turkeltaub, Peter E., Chambers, Catherine E., Martin, Kelly C., Rennert, Rebecca, Giannetti, Margot, Dromerick, Alexander W., Ichord, Rebecca N., Carpenter, Jessica L., Berl, Madison M., and Gaillard, William D.

Published
2022

6. Acute flaccid myelitis: cause, diagnosis, and management

Author

Murphy, Olwen C, Messacar, Kevin, Benson, Leslie, Bove, Riley, Carpenter, Jessica L, Crawford, Thomas, Dean, Janet, DeBiasi, Roberta, Desai, Jay, Elrick, Matthew J, Farias-Moeller, Raquel, Gombolay, Grace Y, Greenberg, Benjamin, Harmelink, Matthew, Hong, Sue, Hopkins, Sarah E, Oleszek, Joyce, Otten, Catherine, Sadowsky, Cristina L, Schreiner, Teri L, Thakur, Kiran T, Van Haren, Keith, Carballo, Carolina M, Chong, Pin Fee, Fall, Amary, Gowda, Vykuntaraju K, Helfferich, Jelte, Kira, Ryutaro, Lim, Ming, Lopez, Eduardo L, Wells, Elizabeth M, Yeh, E Ann, Pardo, Carlos A, group, AFM working, Salazar-Camelo, Andrea, Mithal, Divakar, Wilson-Murphy, Molly, Bauer, Andrea, Watkins, Colyn, Abzug, Mark, Dominguez, Samuel, Press, Craig, Yang, Michele, Ahsan, Nusrat, Ramos-Platt, Leigh, Tiongson, Emmanuelle, Seruya, Mitchel, Tilton, Ann, Katz, Elana, Kirschen, Matthew, Shah, Apurva, Ulloa, Erlinda, Yum, Sabrina, Mondok, Lileth, Blaufuss, Megan, Rosenfeld, Amy, Vargas, Wendy, Zucker, Jason, Yeshokumar, Anusha, Navis, Allison, Chao, Kristen, Hagen, Kaitlin, Melicosta, Michelle, Porter, Courtney, Tunney, Margaret, Scheuermann, Richard, Duggal, Priya, Pekosz, Andrew, Bayliss, Amy, Moore, Meghan, Belzberg, Allan, Bembea, Melania, O'Brien, Caitlin, Riggs, Rebecca, Nance, Jessica, Milstone, Aaron, Rice, Jessica, Garcia-Dominguez, Maria A, Flanagan, Eoin, Tillema, Jan-Mendelt, Bosques, Glendaliz, Bhatia, Sonal, Gordon-Lipkin, Eliza, Deike, Dawn, Revivo, Gadi, Zlotolow, Dan, deFiebre, Gabrielle, Lazerow, Peggy, Lotze, Timothy, Bitnun, Ari, Davidge, Kristen, Vajsar, Jiri, Moore, Amy, Konersman, Chamindra, Nash, Kendall, Strober, Jonathan, Gupta, Nalin, Chiu, Charles, Sweeney, Michael, and Jackson, William

Subjects
Biomedical and Clinical Sciences, Clinical Sciences, Health Sciences, Infectious Diseases, Rehabilitation, Rare Diseases, Neurosciences, Infection, Good Health and Well Being, Central Nervous System Viral Diseases, Child, Enterovirus Infections, Global Health, Humans, Magnetic Resonance Imaging, Muscle Hypotonia, Muscle Weakness, Myelitis, Neuromuscular Diseases, Patient Outcome Assessment, AFM working group, Medical and Health Sciences, General & Internal Medicine, Biomedical and clinical sciences, Health sciences
Abstract

Acute flaccid myelitis (AFM) is a disabling, polio-like illness mainly affecting children. Outbreaks of AFM have occurred across multiple global regions since 2012, and the disease appears to be caused by non-polio enterovirus infection, posing a major public health challenge. The clinical presentation of flaccid and often profound muscle weakness (which can invoke respiratory failure and other critical complications) can mimic several other acute neurological illnesses. There is no single sensitive and specific test for AFM, and the diagnosis relies on identification of several important clinical, neuroimaging, and cerebrospinal fluid characteristics. Following the acute phase of AFM, patients typically have substantial residual disability and unique long-term rehabilitation needs. In this Review we describe the epidemiology, clinical features, course, and outcomes of AFM to help to guide diagnosis, management, and rehabilitation. Future research directions include further studies evaluating host and pathogen factors, including investigations into genetic, viral, and immunological features of affected patients, host-virus interactions, and investigations of targeted therapeutic approaches to improve the long-term outcomes in this population.

Published
2021

7. Spectrum of cerebral arteriopathies in children with arterial ischemic stroke.

Author

Rafay, Mubeen F, Shapiro, Kevin A, Surmava, Ann-Marie, deVeber, Gabrielle A, Kirton, Adam, Fullerton, Heather J, Amlie-Lefond, Catherine, Weschke, Bernhard, Dlamini, Nomazulu, Carpenter, Jessica L, Mackay, Mark T, Rivkin, Michael, Linds, Alexandra, and Bernard, Timothy J

Subjects
Neurosciences, Stroke, Clinical Research, Brain Disorders, Pediatric, Adolescent, Age of Onset, Aneurysm, Dissecting, Anticoagulants, Brain Ischemia, Cerebral Arterial Diseases, Cerebral Infarction, Child, Child, Preschool, Female, Fibrinolytic Agents, Global Health, Headache, Humans, Infant, Infant, Newborn, Intracranial Aneurysm, Male, Prospective Studies, Recurrence, Registries, Risk Factors, Treatment Outcome, Vasculitis, Central Nervous System, International Pediatric Stroke Study (IPSS) Group, Aortic Dissection, Clinical Sciences, Cognitive Sciences, Neurology & Neurosurgery
Abstract

ObjectiveTo determine that children with arterial ischemic stroke (AIS) due to an identifiable arteriopathy are distinct from those without arteriopathy and that each arteriopathy subtype has unique and recognizable clinical features.MethodsWe report a large, observational, multicenter cohort of children with AIS, age 1 month to 18 years, enrolled in the International Pediatric Stroke Study from 2003 to 2014. Clinical and demographic differences were compared by use of the Fisher exact test, with linear step-up permutation min-p adjustment for multiple comparisons. Exploratory analyses were conducted to evaluate differences between cases of AIS with and without arteriopathy and between arteriopathy subtypes.ResultsOf 2,127 children with AIS, 725 (34%) had arteriopathy (median age 7.45 years). Arteriopathy subtypes included dissection (27%), moyamoya (24.5%), focal cerebral arteriopathy-inflammatory subtype (FCA-i; 15%), diffuse cerebral vasculitis (15%), and nonspecific arteriopathy (18.5%). Children with arteriopathic AIS were more likely to present between 6 and 9 years of age (odds ratio [OR] 1.93, p = 0.029) with headache (OR 1.55, p = 0.023), multiple infarctions (OR 2.05, p < 0.001), sickle cell anemia (OR 2.9, p = 0.007), and head/neck trauma (OR 1.93, p = 0.018). Antithrombotic use and stroke recurrence were higher in children with arteriopathy. Among arteriopathy subtypes, dissection was associated with male sex, older age, headache, and anticoagulant use; FCA-i was associated with hemiparesis and single infarcts; moyamoya was associated with seizures and recurrent strokes; and vasculitis was associated with bilateral infarctions.ConclusionSpecific clinical profiles are associated with cerebral arteriopathies in children with AIS. These observations may be helpful indicators in guiding early diagnosis and defining subgroups who may benefit most from future therapeutic trials.

Published
2020

22. Time to Treatment in Pediatric Convulsive Refractory Status Epilepticus: The Weekend Effect

Author

Barcia Aguilar, Cristina, Amengual-Gual, Marta, Sánchez Fernández, Iván, Abend, Nicholas S., Anderson, Anne, Appavu, Brian, Arya, Ravindra, Brenton, J. Nicholas, Carpenter, Jessica L., Chapman, Kevin E., Clark, Justice, Farias-Moeller, Raquel, Gaillard, William D., Gaínza-Lein, Marina, Glauser, Tracy, Goldstein, Joshua L., Goodkin, Howard P., Guerriero, Rejean M., Huh, Linda, Lai, Yi-Chen, McDonough, Tiffani L., Mikati, Mohamad A., Morgan, Lyndsey A., Novotny, Edward J., Ostendorf, Adam, Payne, Eric T., Peariso, Katrina, Piantino, Juan, Riviello, James, Sannagowdara, Kumar, Sheehan, Theodore, Sands, Tristan T., Tasker, Robert C., Tchapyjnikov, Dmitry, Topjian, Alexis A., Vasquez, Alejandra, Wainwright, Mark S., Wilfong, Angus A., Williams, Korwyn, and Loddenkemper, Tobias

Published
2021
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23. Acute flaccid myelitis: cause, diagnosis, and management

Author

Salazar-Camelo, Andrea, Mithal, Divakar, Wilson-Murphy, Molly, Bauer, Andrea, Watkins, Colyn, Abzug, Mark, Dominguez, Samuel, Press, Craig, Yang, Michele, Ahsan, Nusrat, Ramos-Platt, Leigh, Tiongson, Emmanuelle, Seruya, Mitchel, Tilton, Ann, Katz, Elana, Kirschen, Matthew, Shah, Apurva, Ulloa, Erlinda, Yum, Sabrina, Mondok, Lileth, Blaufuss, Megan, Rosenfeld, Amy, Vargas, Wendy, Zucker, Jason, Yeshokumar, Anusha, Navis, Allison, Chao, Kristen, Hagen, Kaitlin, Melicosta, Michelle, Porter, Courtney, Tunney, Margaret, Scheuermann, Richard, Duggal, Priya, Pekosz, Andrew, Bayliss, Amy, Moore, Meghan, Belzberg, Allan, Bembea, Melania, O'Brien, Caitlin, Riggs, Rebecca, Nance, Jessica, Milstone, Aaron, Rice, Jessica, Garcia-Dominguez, Maria A., Flanagan, Eoin, Tillema, Jan-Mendelt, Bosques, Glendaliz, Bhatia, Sonal, Gordon-Lipkin, Eliza, Deike, Dawn, Revivo, Gadi, Zlotolow, Dan, deFiebre, Gabrielle, Lazerow, Peggy, Lotze, Timothy, Bitnun, Ari, Davidge, Kristen, Vajsar, Jiri, Moore, Amy, Konersman, Chamindra, Nash, Kendall, Strober, Jonathan, Gupta, Nalin, Chiu, Charles, Sweeney, Michael, Jackson, William, Simon, Dennis, Thakkar, Kavita, Cheng, Jonathan, Luce, John, Das, Suman, Vogt, Matthew, Vu, NgocHanh, Gofshteyn, Jacqueline, Makhani, Naila, Patel, Payal, Murphy, Olwen C, Messacar, Kevin, Benson, Leslie, Bove, Riley, Carpenter, Jessica L, Crawford, Thomas, Dean, Janet, DeBiasi, Roberta, Desai, Jay, Elrick, Matthew J, Farias-Moeller, Raquel, Gombolay, Grace Y, Greenberg, Benjamin, Harmelink, Matthew, Hong, Sue, Hopkins, Sarah E, Oleszek, Joyce, Otten, Catherine, Sadowsky, Cristina L, Schreiner, Teri L, Thakur, Kiran T, Van Haren, Keith, Carballo, Carolina M, Chong, Pin Fee, Fall, Amary, Gowda, Vykuntaraju K, Helfferich, Jelte, Kira, Ryutaro, Lim, Ming, Lopez, Eduardo L, Wells, Elizabeth M, Yeh, E Ann, and Pardo, Carlos A

Published
2021
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25. Longitudinal evaluation of structural brain alterations in two established mouse models of Gulf War Illness.

Author

Carpenter, Jessica M., Hughes, Sarah N., and Filipov, Nikolay M.

Subjects
PERSIAN Gulf syndrome, MAGNETIC resonance imaging, BRAIN cortical thickness, PYRIDOSTIGMINE bromide, NERVE gases
Abstract

Gulf War Illness (GWI) affects nearly 30% of veterans from the 1990-1991 Gulf War (GW) and is a multi-symptom illness with many neurological effects attributed to in-theater wartime chemical overexposures. Brain-focused studies have revealed persistent structural and functional alterations in veterans with GWI, including reduced volumes, connectivity, and signaling that correlate with poor cognitive and motor performance. GWI symptomology components have been recapitulated in rodent models as behavioral, neurochemical, and neuroinflammatory aberrations. However, preclinical structural imaging studies remain limited. This study aimed to characterize the progression of brain structural alterations over the course of 12 months in two established preclinical models of GWI. In the PB/PM model, male C57BL/6 J mice (8-9 weeks) received daily exposure to the nerve agent prophylactic pyridostigmine bromide (PB) and the pyrethroid insecticide permethrin (PM) for 10 days. In the PB/DEET/CORT/DFP model, mice received daily exposure to PB and the insect repellent DEET (days 1-14) and corticosterone (CORT; days 7-14). On day 15, mice received a single injection of the sarin surrogate diisopropylfluorophosphate (DFP). Using a Varian 7 T Bore MRI System, structural (sagittal T2-weighted) scans were performed at 6-, 9-, and 12-months post GWI exposures. Regions of interest, including total brain, ventricles, cortex, hippocampus, cerebellum, and brainstem were delineated in the open source Aedes Toolbox in MATLAB, followed by brain volumetric and cortical thickness analyses in ImageJ. Limited behavioral testing 1 month after the last MRI was also performed. The results of this study compare similarities and distinctions between these exposure paradigms and aid in the understanding of GWI pathogenesis. Major similarities among the models include relative ventricular enlargement and reductions in hippocampal volumes with age. Key differences in the PB/DEET/CORT/DFP model included reduced brainstem volumes and an early and persistent loss of total brain volume, while the PB/PM model produced reductions in cortical thickness with age. Behaviorally, at 13 months, motor function was largely preserved in both models. However, the GWI mice in the PB/DEET/CORT/DFP model exhibited an elevation in anxiety-like behavior. [ABSTRACT FROM AUTHOR]

Published
2024
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28. Risk of Recurrent Arterial Ischemic Stroke in Childhood

Author

Fullerton, Heather J, Wintermark, Max, Hills, Nancy K, Dowling, Michael M, Tan, Marilyn, Rafay, Mubeen F, Elkind, Mitchell SV, Barkovich, A James, deVeber, Gabrielle A, Plumb, Patricia A, Benedict, Susan L, Bernard, Timothy J, Fox, Christine K, Friedman, Neil R, Lo, Warren D, Ichord, Rebecca N, Mackay, Mark T, Kirton, Adam, Hernandez-Chavez, Marta I, Humphreys, Peter, Jordan, Lori C, Sultan, Sally, Rivkin, Michael J, Titomanlio, Luigi, Kovacevic, Gordana S, Yager, Jerome Y, Amlie-Lefond, Catherine, Dlamini, Nomazulu, Condie, John, Yeh, Ann, Kneen, Rachel, Bjornson, Bruce, Pergami, Paola, Zou, Li Ping, Elbers, Jorina M, Abdalla, Abdalla, Chan, Anthony K, Farooq, Osman, Lim, Mingming J, Carpenter, Jessica L, Pavlakis, Steven, Wong, Virginia C, and Forsyth, Robert

Subjects
Paediatrics, Biomedical and Clinical Sciences, Brain Disorders, Pediatric, Stroke, Prevention, Neurosciences, Atherosclerosis, Adolescent, Brain Ischemia, Cerebral Arterial Diseases, Child, Child, Preschool, Cohort Studies, Female, Follow-Up Studies, Humans, Infant, Internationality, Male, Prospective Studies, Recurrence, Risk Factors, child, pediatrics, risk factor, stroke, vaccination, VIPS Investigators, Cardiorespiratory Medicine and Haematology, Clinical Sciences, Neurology & Neurosurgery, Clinical sciences, Allied health and rehabilitation science
Abstract

Background and purposePublished cohorts of children with arterial ischemic stroke (AIS) in the 1990s to early 2000s reported 5-year cumulative recurrence rates approaching 20%. Since then, utilization of antithrombotic agents for secondary stroke prevention in children has increased. We sought to determine rates and predictors of recurrent stroke in the current era.MethodsThe Vascular Effects of Infection in Pediatric Stroke (VIPS) study enrolled 355 children with AIS at 37 international centers from 2009 to 2014 and followed them prospectively for recurrent stroke. Index and recurrent strokes underwent central review and confirmation, as well as central classification of causes of stroke, including arteriopathies. Other predictors were measured via parental interview or chart review.ResultsOf the 355 children, 354 survived their acute index stroke, and 308 (87%) were treated with an antithrombotic medication. During a median follow-up of 2.0 years (interquartile range, 1.0-3.0), 40 children had a recurrent AIS, and none had a hemorrhagic stroke. The cumulative stroke recurrence rate was 6.8% (95% confidence interval, 4.6%-10%) at 1 month and 12% (8.5%-15%) at 1 year. The sole predictor of recurrence was the presence of an arteriopathy, which increased the risk of recurrence 5-fold when compared with an idiopathic AIS (hazard ratio, 5.0; 95% confidence interval, 1.8-14). The 1-year recurrence rate was 32% (95% confidence interval, 18%-51%) for moyamoya, 25% (12%-48%) for transient cerebral arteriopathy, and 19% (8.5%-40%) for arterial dissection.ConclusionsChildren with AIS, particularly those with arteriopathy, remain at high risk for recurrent AIS despite increased utilization of antithrombotic agents. Therapies directed at the arteriopathies themselves are needed.

Published
2016

30. The onset of pediatric refractory status epilepticus is not distributed uniformly during the day

Author

Sánchez Fernández, Iván, Gaínza-Lein, Marina, Abend, Nicholas S., Amengual-Gual, Marta, Anderson, Anne, Arya, Ravindra, Brenton, J. Nicholas, Carpenter, Jessica L., Chapman, Kevin E., Clark, Justice, Farias-Moeller, Raquel, Davis Gaillard, William, Glauser, Tracy A., Goldstein, Joshua, Goodkin, Howard P., Guerriero, Réjean M., Hecox, Kurt, Jackson, Michele, Kapur, Kush, Kelley, Sarah A., Kossoff, Eric H.W., Lai, Yi-Chen, McDonough, Tiffani L., Mikati, Mohamad A., Morgan, Lindsey A., Novotny, Edward J., Ostendorf, Adam P., Payne, Eric T., Peariso, Katrina, Piantino, Juan, Riviello, James J., Jr., Sannagowdara, Kumar, Stafstrom, Carl E., Tasker, Robert C., Tchapyjnikov, Dmitry, Topjian, Alexis A., Vasquez, Alejandra, Wainwright, Mark S., Wilfong, Angus, Williams, Korwyn, and Loddenkemper, Tobias

Published
2019
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32. Super-Refractory Status Epilepticus in Children: A Retrospective Cohort Study

Author

Vasquez, Alejandra, Farias-Moeller, Raquel, Sánchez-Fernández, Iván, Abend, Nicholas S., Amengual-Gual, Marta, Anderson, Anne, Arya, Ravindra, Brenton, James N., Carpenter, Jessica L., Chapman, Kevin, Clark, Justice, Gaillard, William D., Glauser, Tracy, Goldstein, Joshua L., Goodkin, Howard P., Guerriero, Rejean M., Lai, Yi-Chen, McDonough, Tiffani L., Mikati, Mohamad A., Morgan, Lindsey A., Novotny, Edward J., Ostendorf, Adam P., Payne, Eric T., Peariso, Katrina, Piantino, Juan, Riviello, James J., Sands, Tristan T., Sannagowdara, Kumar, Tasker, Robert C., Tchapyjnikov, Dmitry, Topjian, Alexis, Wainwright, Mark S., Wilfong, Angus, Williams, Korwyn, and Loddenkemper, Tobias

Published
2021
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35. Hospital Emergency Treatment of Convulsive Status Epilepticus: Comparison of Pathways From Ten Pediatric Research Centers

Author

Vasquez, Alejandra, Gaínza-Lein, Marina, Sánchez Fernández, Iván, Abend, Nicholas S., Anderson, Anne, Brenton, J Nicholas, Carpenter, Jessica L., Chapman, Kevin, Clark, Justice, Gaillard, William D., Glauser, Tracy, Goldstein, Joshua, Goodkin, Howard P., Lai, Yi-Chen, Loddenkemper, Tobias, McDonough, Tiffani L., Mikati, Mohamad A., Nayak, Anuranjita, Payne, Eric, Riviello, James, Tchapyjnikov, Dmitry, Topjian, Alexis A., Wainwright, Mark S., and Tasker, Robert C.

Published
2018
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37. Dyslipidemia in Children With Arterial Ischemic Stroke: Prevalence and Risk Factors

Author

Bernard, Tim, Dowling, Michael, Hernandez, Marta, Rivkin, Michael, Kopyta, Ilona, Ichord, Rebecca, Benedict, Susan, Mackay, Mark, Kirton, Adam, Zafeiriou, Dimitrios, Troncoso, Monica, Yager, Jerome, Abraham, Lisa, Lo, Warren, Gonzalez, Veronica, Saengpattrachai, Montri, Chan, Anthony, Abdallah, Abdallah, Brankovic-Sreckovic, Vesna, Kolk, Anneli, Carpenter, Jessica, Kovacevic, Gordana, Amlie-Lefond, Catherine, Steinlin, Maja, Paolicchi, Juliann, Carell, Monroe, Jr, Bjornson, Bruce, Kosofsky, Barry, Wong, Virginia, Pergami, Paola, Friedman, Neil, Guang, Yang, Humphreys, Peter, Nowak-Göttl, Ulrike, Ferriero, Donna, Xavier, Frederico, Fryer, Robert, Andrade Alveal, Lucila, Altuna, Diana, Felling, Ryan, Pavlakis, Steven, Grabowski, Eric, Golomb, Meredith, Noetzel, Michael, Khoury, Chaouki, Lerner, Norma, Blair, Amanda, Rafay, Mubeen, Sultan, Sally, DeVeber, Gabrielle, Linds, Alexandra, and Elkind, Mitchell S.V.

Published
2018
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39. Pediatric status epilepticus management by Emergency Medical Services (the pSERG cohort)

Author

Amengual-Gual, Marta, primary, Sánchez Fernández, Iván, additional, Vasquez, Alejandra, additional, Abend, Nicholas S., additional, Anderson, Anne, additional, Arya, Ravindra, additional, Barcia Aguilar, Cristina, additional, Brenton, J. Nicholas, additional, Carpenter, Jessica L., additional, Chapman, Kevin E., additional, Clark, Justice, additional, Farias-Moeller, Raquel, additional, Gaillard, William D., additional, Glauser, Tracy A., additional, Goldstein, Joshua L., additional, Goodkin, Howard P., additional, Lai, Yi-Chen, additional, Mikati, Mohamad A., additional, Morgan, Lindsey A., additional, Novotny, Edward J., additional, Ostendorf, Adam P., additional, Payne, Eric T., additional, Peariso, Katrina, additional, Piantino, Juan, additional, Reece, Latania, additional, Riviello, James J., additional, Sannagowdara, Kumar, additional, Sheehan, Theodore, additional, Tasker, Robert C., additional, Tchapyjnikov, Dmitry, additional, Topjian, Alexis A., additional, Wainwright, Mark S., additional, Wilfong, Angus, additional, Williams, Korwyn, additional, and Loddenkemper, Tobias, additional

Published
2023
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42. First-line medication dosing in pediatric refractory status epilepticus

Author

Vasquez, Alejandra, Gaínza-Lein, Marina, Abend, Nicholas S., Amengual-Gual, Marta, Anderson, Anne, Arya, Ravindra, Brenton, J. Nicholas, Carpenter, Jessica L., Chapman, Kevin, Clark, Justice, Farias-Moeller, Raquel, Gaillard, William D., Glauser, Tracy, Goldstein, Joshua L., Goodkin, Howard P., Guerriero, Rejean M., Kapur, Kush, Lai, Yi-Chen, McDonough, Tiffani L., Mikati, Mohamad A., Morgan, Lindsey A., Novotny, Edward J., Ostendorf, Adam P., Payne, Eric T., Peariso, Katrina, Piantino, Juan, Riviello, James J., Sannagowdara, Kumar, Tasker, Robert C., Tchapyjnikov, Dmitry, Topjian, Alexis, Wainwright, Mark S., Wilfong, Angus, Williams, Korwyn, Loddenkemper, Tobias, Bansal, Seema, Kelley, Sarah, Stafstrom, Carl, Kossoff, Eric, Habela, Christa, Lewis, Dalila, Stanfield, Tony, Sculier, Claudine, Aguilar, Cristina Barcia, Sansevere, Arnold, Sacco, Melissa, Duncan, Abby, McCoy, Jordan, DaSilva-Chiodo, Kathryn, Faist, Robert, Santel, Daniel, LaFay, Victor, Clark, Peggy, Borror, Sarah, Debs, Andrea, Clohessy, Caitlin, Weber, Amanda, Yuliati, Asri, Luat, Aimee, Singh, Azara, Helseth, Ashley, Turner, David, Fernandes, Cecilia, Tran, Linh, McLean, Melissa, Nayak, Anuranjita, Riviello, James J, Jr, Hecox, Kurt, Nallamothu, Rupa, Rehborg, Rebecca, Goldstein, David, Heinzen Cox, Erin, Malone, Colin, Thornburg, Olivia, Grinspan, Zachary, Basma, Natasha, Appavu, Brian, Burrows, Brian, Dyar, Beata, Mishler, Laura, Lee-Eng, Jacqueline, Streb, Madison, Hahn, Cecil, Lalgudi Ganesan, Saptharishi (Rishi), Huh, Linda, and Martic, Nela

Published
2020
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44. Electroencephalographic Reporting for Refractory Status Epilepticus

Author

Sansevere, Arnold J., Arya, Ravindra, Sánchez Fernández, Iván, Gaillard, William D., Tasker, Robert C., Lai, Yi-Chen, Anderson, Anne E., Tchapyjnikov, Dmitry, Chapman, Kevin E., Brenton, J. Nicholas, Carpenter, Jessica L., Gaínza-Lein, Marina, Goldstein, Joshua L., Goodkin, Howard P., Jackson, Michele C., Kapur, Kush, Mikati, Mohamad A., Peariso, Katrina, Glauser, Tracy A., Topjian, Alexis A., Wainwright, Mark, Wilfong, Angus A., Williams, Korwyn L., Loddenkemper, Tobias, and Abend, Nicholas S.

Published
2019
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48. Survey of Pediatric ICU EEG Monitoring–Reassessment After a Decade

Author

Fung, France W., primary, Carpenter, Jessica L., additional, Chapman, Kevin E., additional, Gallentine, William, additional, Giza, Christopher C., additional, Goldstein, Joshua L., additional, Hahn, Cecil D., additional, Loddenkemper, Tobias, additional, Matsumoto, Joyce H., additional, Press, Craig A., additional, Riviello, James J., additional, and Abend, Nicholas S., additional

Published
2023
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50. Development and validation of a seizure prediction model in critically ill children

Author

Yang, Amy, Arndt, Daniel H., Berg, Robert A., Carpenter, Jessica L., Chapman, Kevin E., Dlugos, Dennis J., Gallentine, William B., Giza, Christopher C., Goldstein, Joshua L., Hahn, Cecil D., Lerner, Jason T., Loddenkemper, Tobias, Matsumoto, Joyce H., Nash, Kendall B., Payne, Eric T., Sánchez Fernández, Iván, Shults, Justine, Topjian, Alexis A., Williams, Korwyn, Wusthoff, Courtney J., and Abend, Nicholas S.

Published
2015
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