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1. Childhood Absence Epilepsy

Author

Vetri, Luigi, primary, Costanza, Carola, additional, Siciliano, Margherita, additional, Precenzano, Francesco, additional, Gallai, Beatrice, additional, and Carotenuto, Marco, additional

Published
2024
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3. Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Published
2022
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4. D-aspartate oxidase gene duplication induces social recognition memory deficit in mice and intellectual disabilities in humans

Author

Lombardo, Barbara, Pagani, Marco, De Rosa, Arianna, Nunziato, Marcella, Migliarini, Sara, Garofalo, Martina, Terrile, Marta, D’Argenio, Valeria, Galbusera, Alberto, Nuzzo, Tommaso, Ranieri, Annaluisa, Vitale, Andrea, Leggiero, Eleonora, Di Maio, Anna, Barsotti, Noemi, Borello, Ugo, Napolitano, Francesco, Mandarino, Alessandra, Carotenuto, Marco, Heresco-Levy, Uriel, Pasqualetti, Massimo, Malatesta, Paolo, Gozzi, Alessandro, Errico, Francesco, Salvatore, Francesco, Pastore, Lucio, and Usiello, Alessandro

Published
2022
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5. Neurobiology and medico-legal aspects of suicides among older adults: a narrative review.

Author

Sessa, Francesco, Polito, Rita, Rosi, Giuseppe Li, Salerno, Monica, Esposito, Massimiliano, Pisanelli, Daniela, Ministeri, Federica, Messina, Antonietta, Carotenuto, Marco, Chieffi, Sergio, Messina, Giovanni, and Monda, Marcellino

Subjects
FAMILY support, OLDER people, SUICIDE risk factors, SUICIDAL behavior, PSYCHOSOCIAL factors
Abstract

The task of preventing suicide in older adults is an important social burden as older adults aged above 65 are exposed to singular psychological aspects that increase suicide risks. Moreover, when an older adult corpse is found, the medico-legal inspection represents a fundamental tool to identify the exact cause of death, classifying or excluding it as suicide. In this scenario, this review aims to explore the neurobiological factors that could be related to suicidal behavior in older adults. A further goal of this review is the exploration of the medico-legal aspects surrounding older adult suicides, clarifying the importance of forensic investigation. Particularly, this review examines issues such as neurotransmitter imbalances, cognitive impairment, neuroinflammation, psychosocial factors related to geriatric suicide, and neurodegenerative diseases. Additionally, medico-legal aspects such as policy considerations, legal frameworks, mental health assessments, ethical implications and forensic investigation were explored. Considering the importance of this phenomenon, especially in western countries, a need has emerged for focused screening tools on suicidal behavior among older adults, in order to contain it. Therefore, this review makes an exhaustive appraisal of the literature giving insights into the delicate interplay between neurobiology as well as mental health in relation to older adult suicide within a medico-legal context. The comprehension of different aspects about this complex phenomenon is fundamental to propose new and more effective interventions, supporting tailored initiatives such as family support and improving healthcare, specifically towards vulnerable ageing societies to reduce older adult suicide risks. [ABSTRACT FROM AUTHOR]

Published
2024
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7. Quality of Life in Children with Neurofibromatosis Type 1: Agreement between Parents and Patients, and the Role of Disease Severity and Visibility.

Author

Cavallo, Nicola Davide, Maietta, Paola, Perrotta, Silverio, Moretta, Pasquale, Carotenuto, Marco, Esposito, Maria, Santangelo, Gabriella, and Santoro, Claudia

Subjects
STATISTICAL correlation, SELF-evaluation, DATA analysis, PARENT-child relationships, QUESTIONNAIRES, NEUROFIBROMATOSIS 1, SEVERITY of illness index, MANN Whitney U Test, FUNCTIONAL status, EMOTIONS, DESCRIPTIVE statistics, QUALITY of life, RESEARCH, SOCIAL adjustment, STATISTICS, PSYCHOLOGY of parents, DATA analysis software, EVALUATION, CHILDREN
Abstract

Background: Neurofibromatosis type 1 (NF1) is a genetic disorder that affects multiple systems in the body, often leading to physical disfigurements and a wide range of clinical symptoms. This study aims to investigate the relationship between NF1 severity and visibility and the quality of life (QoL) in children. Methods: The Pediatric Quality of Life Inventory (PedsQL) and a modified version of the Ablon scale were used to assess QoL and NF1 severity and visibility, respectively. Self-reported and parent-reported QoL scores were compared, and the associations between NF1 severity/visibility and QoL were explored. Results: Thirty-eight pediatric NF1 patients and their parents were enrolled. QoL scores did not differ significantly between patient self-reports and parent reports. However, correlational analyses revealed that higher NF1 severity was associated with lower physical QoL in patients, and greater NF1 visibility was linked to lower physical and social QoL. For parents, higher NF1 severity correlated with lower school functioning, whereas NF1 visibility did not show a significant correlation with QoL. Conclusion: The severity and visibility of NF1 have distinct impacts on various aspects of QoL in children, highlighting the need for tailored interventions that address both physical and psychological challenges. These findings underscore the importance of comprehensive care approaches in managing NF1 in pediatric populations. [ABSTRACT FROM AUTHOR]

Published
2024
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9. Brain Neuromodulation Effects on Sport and Nutrition: A Narrative Review

Author

Limone, Pierpaolo, primary, Moscatelli, Fiorenzo, additional, Scarinci, Alessia, additional, Carotenuto, Marco, additional, Messina, Antonietta, additional, Monda, Marcellino, additional, Dipace, Anna, additional, La Marra, Marco, additional, Villano, Ines, additional, Bassi, Paola, additional, Polito, Rita, additional, and Messina, Giovanni, additional

Published
2024
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21. The Groupal Device: Value And Usage In Neuro And Psychomotor Therapy Of Developmental Age

Author

Cerroni Francesco, Carotenuto Marco, Bonifacio Andrea, Della Corte Giuseppina, Nocerino Ludovica Cira, Martino Federica, Bianco Enza, Salatiello Raffaella, and Albano Paola Alessandra

Subjects
General Medicine
Abstract

The group represents the social element in which every individual can experience them-selves after the achievement of the main stages of the neuro-psychomotor development, particularly in the affective-relational, neuropsychological and cognitive areas, and is thus identified as a fundamental device to support rehabilitation therapy. Early in a child’s development, social skills begin to maturate and their development path-way merges with different groups with a specific architecture which modifies and increases these skills over time. As a result, it is necessary to identify the process that leads from the exclusive belonging to the family-group to the need to prioritize comparison with peers to finally arrive at the interdependent social groups in the collectivity/community. Each group has distinct characteristics that move from its social dimension to the cross-sectional com-ponent of its matrix, where individuals’ desires and beliefs are based. The group’s evolution will allow the initial dimensional plan to be expanded, resulting in participants sharing inten-tions and goals. The group is a powerful tool at the therapist's disposal who is capable of monitoring variables that can quickly change the intra/interpersonal dynamics of patients undergoing treatment. The groupal therapy underlies clear rules within it, which ensure the observance of normative and setting parameters and the identification of the parameters of effectiveness to assess its progress.

Published
2022

24. Neuropsychiatric Manifestations, Reduced Self-Esteem and Poor Quality of Life in Children and Adolescents with Neurofibromatosis Type 1 (NF1): The Impact of Symptom Visibility and Bullying Behavior

Author

Cavallo, Nicola Davide, primary, Maggi, Gianpaolo, additional, Ferraiuolo, Francesco, additional, Sorrentino, Anna, additional, Perrotta, Silverio, additional, Carotenuto, Marco, additional, Santangelo, Gabriella, additional, and Santoro, Claudia, additional

Published
2023
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25. Epilepsy: A Multifaced Spectrum Disorder

Author

Vetri, Luigi, primary, Roccella, Michele, additional, Parisi, Lucia, additional, Smirni, Daniela, additional, Costanza, Carola, additional, Carotenuto, Marco, additional, and Elia, Maurizio, additional

Published
2023
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27. Correction: La Torre et al. Role of Vitamin E and the Orexin System in Neuroprotection. Brain Sci. 2021, 11, 1098

Author

La Torre, Maria Ester, primary, Villano, Ines, additional, Monda, Marcellino, additional, Messina, Antonietta, additional, Cibelli, Giuseppe, additional, Valenzano, Anna, additional, Pisanelli, Daniela, additional, Panaro, Maria Antonietta, additional, Tartaglia, Nicola, additional, Ambrosi, Antonio, additional, Carotenuto, Marco, additional, Monda, Vincenzo, additional, Messina, Giovanni, additional, and Porro, Chiara, additional

Published
2022
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28. Adolescents with Neuropsychiatric Disorders during the COVID-19 Pandemic: Focus on Emotional Well-Being and Parental Stress

Author

Operto, Francesca Felicia, primary, Scaffidi Abbate, Costanza, additional, Piscitelli, Francesco Tommaso, additional, Olivieri, Miriam, additional, Rizzo, Luigi, additional, Sica, Gianpiero, additional, Labate, Angelo, additional, Roccella, Michele, additional, Carotenuto, Marco, additional, and Pastorino, Grazia Maria Giovanna, additional

Published
2022
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29. Clinical and electroencephalographic features of epilepsy in patients with triple X syndrome: A case series

Author

Dell'Isola, Giovanni Battista, primary, Mencaroni, Elisabetta, additional, Prontera, Paolo, additional, Cara, Giuseppe Di, additional, Ferraro, Luigi, additional, Bonanni, Paolo, additional, Carotenuto, Marco, additional, Iapadre, Giulia, additional, Matricardi, Sara, additional, Operto, Francesca, additional, Orsini, Alessandro, additional, Parisi, Pasquale, additional, Pavone, Piero, additional, Salpietro, Vincenzo, additional, Savasta, Salvatore, additional, Striano, Pasquale, additional, and Verrotti, Alberto, additional

Published
2022
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31. Behavioral and Sleep Disorders in Children and Adolescents following COVID-19 Disease: A Case-Control Study.

Author

Miraglia del Giudice, Michele, Klain, Angela, Dinardo, Giulio, D'Addio, Elisabetta, Bencivenga, Chiara Lucia, Fontanella, Cristina, Decimo, Fabio, Umano, Giuseppina Rosaria, Siciliano, Margherita, Carotenuto, Marco, and Indolfi, Cristiana

Subjects
SLEEP-wake cycle, COVID-19, ACADEMIC medical centers, CASE-control method, BEHAVIOR disorders in children, SLEEP disorders, RISK assessment, CHILD Behavior Checklist, COMPARATIVE studies, QUESTIONNAIRES, DESCRIPTIVE statistics, SLEEP apnea syndromes, CHI-squared test, STAY-at-home orders, ANXIETY, DATA analysis software, COVID-19 pandemic, PSYCHOLOGICAL stress, DISEASE risk factors, CHILDREN, ADOLESCENCE
Abstract

Introduction: Recent studies show that neuropsychiatric disorders are the most frequent sequelae of COVID-19 in children. Purpose: Our work aimed to evaluate the impact of SARS-CoV-2 infection on behavior and sleep in children and adolescents. Materials and Methods: We enrolled 107 patients aged 1.5–18 years who contracted COVID-19 between one year and one month prior to data collection, referred to the University of Campania Luigi Vanvitelli in Italy. We asked their parents to complete two standardized questionnaires for the assessment of behavior (Child Behavior CheckList (CBCL)) and sleep (Sleep Disturbance Scale for Children (SLDS)). We analysed and compared the results with a control group (pre-COVID-19 pandemic). Results: In the COVID-19 group, the major results were found for sleep breathing disorders, sleep–wake transition disorders and disorders of initiating and maintaining sleep for the SDSC questionnaire, and internalizing scale, total scale and anxiety/depression for the CBCL questionnaire. The comparison of the CBCL results of the cases with the controls revealed statistically significant differences for the following items: internalizing scale, externalizing scale, somatic complaints, total score, thought problems [(p < 0.01)], anxious/depressed problems and withdrawn [(p < 0.001)]. Conclusions: COVID-19 has impacted children's and adolescents' mental health. Adolescents were the most affected patient group for internalizing problems, including anxiety and depression. [ABSTRACT FROM AUTHOR]

Published
2023
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33. Mystery(n) Phenotypic Presentation in Europeans: Report of Three Further Novel Missense RNF213 Variants Leading to Severe Syndromic Forms of Moyamoya Angiopathy and Literature Review

Author

Santoro, Claudia, primary, Mirone, Giuseppe, additional, Zanobio, Mariateresa, additional, Ranucci, Giusy, additional, D’Amico, Alessandra, additional, Cicala, Domenico, additional, Iascone, Maria, additional, Bernardo, Pia, additional, Piccolo, Vincenzo, additional, Ronchi, Andrea, additional, Limongelli, Giuseppe, additional, Carotenuto, Marco, additional, Nigro, Vincenzo, additional, Cinalli, Giuseppe, additional, and Piluso, Giulio, additional

Published
2022
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34. Exome sequencing in a child with neurodevelopmental disorder and epilepsy: Variant analysis of the AHNAK2 gene

Author

Vinci, Mirella, primary, Kursula, Petri, additional, Greco, Donatella, additional, Elia, Maurizio, additional, Vetri, Luigi, additional, Schepis, Carmelo, additional, Chiavetta, Valeria, additional, Donadio, Serena, additional, Roccella, Michele, additional, Carotenuto, Marco, additional, Romano, Valentino, additional, and Calì, Francesco, additional

Published
2022
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35. Executive Functions in Overweight and Obese Treatment-Seeking Patients: Cross-Sectional Data and Longitudinal Perspectives

Author

La Marra, Marco, primary, Villano, Ines, additional, Ilardi, Ciro Rosario, additional, Carosella, Mario, additional, Staiano, Maria, additional, Iavarone, Alessandro, additional, Chieffi, Sergio, additional, Messina, Giovanni, additional, Polito, Rita, additional, Porro, Chiara, additional, Scarinci, Alessia, additional, Monda, Vincenzo, additional, Carotenuto, Marco, additional, Di Maio, Girolamo, additional, and Messina, Antonietta, additional

Published
2022
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37. Behavioural Differences in Sensorimotor Profiles: A Comparison of Preschool-Aged Children with Sensory Processing Disorder and Autism Spectrum Disorders

Author

Purpura, G, Cerroni, F, Carotenuto, M, Nacinovich, R, Tagliabue, L, Purpura, Giulia, Cerroni, Francesco, Carotenuto, Marco, Nacinovich, Renata, Tagliabue, Luca, Purpura, G, Cerroni, F, Carotenuto, M, Nacinovich, R, Tagliabue, L, Purpura, Giulia, Cerroni, Francesco, Carotenuto, Marco, Nacinovich, Renata, and Tagliabue, Luca

Abstract

Sensory Processing Disorders (SPDs) define dysfunctions in modulating, organising, and using information from several sensory channels for regulating motor, behavioural, emotional and attention responses. Although SPD can be identified also as an isolated condition in young children, its presence in Autism Spectrum Disorder (ASD) population is really frequent. The study purpose is to explore the SPD clinical expression and the putative correlation with several behavioural aspects both in children with ASD and in those with isolated SPD. Therefore, 43 preschool-aged children (25 ASD vs. 18 SPD) were recruited, and their parents completed three questionnaires (Developmental Profile-3, Sensory Processing Measure–Preschool, Repetitive Behaviour Scale-Revised) to evaluate behavioural alterations and developmental levels. The main result is that both ASD and SPD groups had significantly sensory-related behavioural symptoms, although ASD children seem to be more impaired in all areas. Several significant correlations were found between sensory processing difficulties and repetitive behaviours, but in the SPD group a specific relationship between Body Awareness and Ritualistic/Sameness Behaviour was found. Conversely, in the ASD group, more diffuse interlinks between sensory processing difficulties and motor behaviours were significant. In conclusion, the present study confirms the key role of sensory–motor skills in early diagnosis and intervention among children at risk for neurodevelopmental disorders.

Published
2022

38. Agomelatine: A Potential Multitarget Compound for Neurodevelopmental Disorders.

Author

Savino, Rosa, Polito, Anna Nunzia, Marsala, Gabriella, Ventriglio, Antonio, Di Salvatore, Melanie, De Stefano, Maria Ida, Valenzano, Anna, Marinaccio, Luigi, Bellomo, Antonello, Cibelli, Giuseppe, Monda, Marcellino, Monda, Vincenzo, Messina, Antonietta, Polito, Rita, Carotenuto, Marco, and Messina, Giovanni

Subjects
SEROTONIN antagonists, ATTENTION-deficit hyperactivity disorder, AUTISM spectrum disorders, SEROTONIN agonists, NEUROLOGICAL disorders
Abstract

Agomelatine (AGM) is one of the latest atypical antidepressants, prescribed exclusively for the treatment of depression in adults. AGM belongs to the pharmaceutical class of melatonin agonist and selective serotonin antagonist ("MASS"), as it acts both as a selective agonist of melatonin receptors MT1 and MT2, and as a selective antagonist of 5-HT2C/5-HT2B receptors. AGM is involved in the resynchronization of interrupted circadian rhythms, with beneficial effects on sleep patterns, while antagonism on serotonin receptors increases the availability of norepinephrine and dopamine in the prefrontal cortex, with an antidepressant and nootropic effect. The use of AGM in the pediatric population is limited by the scarcity of data. In addition, few studies and case reports have been published on the use of AGM in patients with attention deficit and hyperactivity disorder (ADHD) and autism spectrum disorder (ASD). Considering this evidence, the purpose of this review is to report the potential role of AGM in neurological developmental disorders. AGM would increase the expression of the cytoskeleton-associated protein (ARC) in the prefrontal cortex, with optimization of learning, long-term memory consolidation, and improved survival of neurons. Another important feature of AGM is the ability to modulate glutamatergic neurotransmission in regions associated with mood and cognition. With its synergistic activity a melatoninergic agonist and an antagonist of 5-HT2C, AGM acts as an antidepressant, psychostimulant, and promoter of neuronal plasticity, regulating cognitive symptoms, resynchronizing circadian rhythms in patients with autism, ADHD, anxiety, and depression. Given its good tolerability and good compliance, it could potentially be administered to adolescents and children. [ABSTRACT FROM AUTHOR]

Published
2023
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39. Impact of COVID-19 Pandemic on Children and Adolescents with Neuropsychiatric Disorders: Emotional/Behavioral Symptoms and Parental Stress

Author

Operto, Francesca Felicia, primary, Coppola, Giangennaro, additional, Vivenzio, Valentina, additional, Scuoppo, Chiara, additional, Padovano, Chiara, additional, de Simone, Valeria, additional, Rinaldi, Rosetta, additional, Belfiore, Gilda, additional, Sica, Gianpiero, additional, Morcaldi, Lucia, additional, D’Onofrio, Floriana, additional, Olivieri, Miriam, additional, Donadio, Serena, additional, Roccella, Michele, additional, Carotenuto, Marco, additional, Viggiano, Andrea, additional, and Pastorino, Grazia Maria Giovanna, additional

Published
2022
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42. Aerobic Exercise and Metabolic Syndrome: The Role of Sympathetic Activity and the Redox System

Author

Monda,Vincenzo, Sessa,Francesco, Ruberto,Maria, Carotenuto,Marco, Marsala,Gabriella, Monda,Marcellino, Cambria,Maria Teresa, Astuto,Marinella, Distefano,Alfio, Messina,Giovanni, Monda, V., Sessa, F., Ruberto, M., Carotenuto, M., Marsala, G., Monda, M., Cambria, M. T., Astuto, M., Distefano, A., and Messina, G.

Subjects
Heart rate, heart rate (hr), cholesterol, physical activity, Specialties of internal medicine, body mass index (bmi), Metabolic syndrome, metabolic syndrome (mets), BMI, RC581-951, HR, MetS, orexin a, Targets and Therapy [Diabetes, Metabolic Syndrome and Obesity], Body mass index, Original Research
Abstract

Vincenzo Monda,1 Francesco Sessa,2 Maria Ruberto,3 Marco Carotenuto,4 Gabriella Marsala,5 Marcellino Monda,1 Maria Teresa Cambria,6 Marinella Astuto,7 Alfio Distefano,6 Giovanni Messina2 1Department of Experimental Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Caserta 81100, Italy; 2Department of Clinical and Experimental Medicine, University of Foggia, Foggia 71121, Italy; 3CDR Santa Maria del Pozzo, Naples 80049, Italy; 4Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Caserta 81100, Italy; 5Struttura Complessa di Farmacia, Azienda Ospedaliero-Universitaria, Ospedali Riuniti di Foggia, Foggia 71121, Italy; 6Section of Medical Biochemistry, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania 95123, Italy; 7Azienda Ospedaliera “Policlinico Vittorio Emanuele”, U.O. di Anestesia e Terapia Intensiva, Catania 95123, ItalyCorrespondence: Francesco SessaDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia 71122, ItalyTel +39 0881 736926Email francesco.sessa@unifg.itBackground: Aerobic exercise can greatly assist in reducing collateral effects of metabolic syndrome (MetS). Moreover, aerobic exercise is associated with sympathetic activation and adaptive responses to sustain muscle engagement, changes in the release of Orexin A, a pleiotropic neuropeptide.Aim: The aim of this study was to analyze the beneficial effects of aerobic exercise without dietary changes, in a cohort of MetS subjects, focusing on the role of sympathetic and orexinergic activity. Several blood parameters linked to MetS ROS production, heart rate, galvanic skin response, d-ROM test, and Orexin A serum levels were evaluated in ten males with MetS (BMI 30– 34.9) before and after a period of 6 months of aerobic exercise compared to ten healthy subjects.Methods: Ten male subjects (aged 54 ± 4.16) with MetS (MetS group) and ten healthy males (aged 49.7 ± 2.79, Healthy group) were told about the study protocol and possible risks, signed the informed consent, and voluntarily participated in the study. Several blood parameters were evaluated in the two tested groups and were re-evaluated in the MetS group after 6 months of training (MetS6M group). The training protocol consisted of more than 30 min/day of walking (average speed of 4.5 km/h) and 3 days/week of aerobic activities (jogging under heart rate control – 120– 140 bpm for 45 min).Results: The results showed that exercise induced a significant increase in GSR and plasma Orexin A but no significant increase in d-ROM values. Significant decreases in the serum ALT enzyme, triglycerides, and total cholesterol were found, while the HDL levels were significantly higher. Finally, a significant reduction of BMI and resting HR were reported.Conclusion: The results of this study confirm that physical activity is associated with sympathetic activation, having a pivotal role against adverse effects linked to MetS. Moreover, this study demonstrates that, in patients with MetS, Orexin A is involved in hormonal adaptations to exercise.Keywords: metabolic syndrome, MetS, Orexin A, body mass index, BMI, heart rate, HR, cholesterol, physical activity

Published
2020

43. Additional file 6 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 6: Supplementary Table 6. Screening tests performed among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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44. Additional file 4 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 4: Supplementary Table 4. Family history of diseases detected among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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45. Additional file 2 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 2: Supplementary Table 2. Main organic causes of vomiting identified in patients with suspected cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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46. Additional file 7 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 7: Supplementary Table 7. Treatments applied in patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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47. Additional file 1 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 1: Supplementary Table 1. Web-based Questionnaire [original language].

Published
2022
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48. Additional file 3 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 3: Supplementary Table 3. Comorbidities recorded among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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49. Additional file 5 of Cyclic vomiting syndrome in children: a nationwide survey of current practice on behalf of the Italian Society of Pediatric Gastroenterology, Hepatology and Nutrition (SIGENP) and Italian Society of Pediatric Neurology (SINP)

Author

Isoldi, Sara, Di Nardo, Giovanni, Mallardo, Saverio, Parisi, Pasquale, Raucci, Umberto, Tambucci, Renato, Quitadamo, Paolo, Salvatore, Silvia, Felici, Enrico, Cisarò, Fabio, Pensabene, Licia, Banzato, Claudia, Strisciuglio, Caterina, Romano, Claudio, Fusco, Patrizia, Rigotti, Francesca, Sansotta, Naire, Caimmi, Silvia, Savasta, Salvatore, Zuin, Giovanna, Di Stefano, Marina, Provera, Silvia, Campanozzi, Angelo, Rossi, Paolo, Gatti, Simona, Corpino, Mara, Alvisi, Patrizia, Martelossi, Stefano, Suppiej, Agnese, Gandullia, Paolo, Verrotti, Alberto, Terrin, Gianluca, Pacenza, Caterina, Fornaroli, Fabiola, Comito, Donatella, D’Arrigo, Stefano, Striano, Pasquale, Raviglione, Federico, Carotenuto, Marco, Orsini, Alessandro, Belcastro, Vincenzo, Di Corcia, Giovanna, Raieli, Vincenzo, Ferilli, Michela Ada Noris, Ruscitto, Claudia, Spadoni, Elisabetta, Grosso, Salvatore, D’Alonzo, Renato, Papa, Amanda, Pavone, Piero, Meli, Mariaclaudia, Velardita, Mario, Mainetti, Martina, Vanacore, Nicola, and Borrelli, Osvaldo

Abstract

Additional file 5: Supplementary Table 5. Triggers recorded among patients with cyclic vomiting syndrome according to specific outpatient clinic.

Published
2022
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50. Neuropsychological Alterations in Children Affected by Obstructive Sleep Apnea Syndrome

Author

Carotenuto, Marco, Roccella, Michele, Operto, Francesca Felicia, Maltese, Agata, Salerno, Margherita, Di Folco, Annabella, Gallai, Beatrice, Parisi, Lucia, and Ruberto, Maria

Subjects
Medical
Abstract

Sleep-related breathing disorders are a group of clinical conditions ranging from habitual snoring to obstructive sleep apnea syndrome (OSAS) during the lifespan. In children, other risk factors are represented by adenotonsillar hypertrophy, rhinitis, nasal structure alteration, cleft palate, velopharyngeal flap surgery, pharyngeal masses, craniofacial malformations, genetic syndrome (i.e. Down syndrome, Crouzon syndrome, and Apert syndrome), genetic hypoplasia mandibular (i.e. Pierre Robin syndrome, Treacher Collins syndrome, Shy-Drager syndrome, and Cornelia De Lange syndrome), craniofacial traumas, chronic or seasonal rhinitis, asthma, neuromuscular syndromes, brainstem pathologies (i.e. Arnold-Chiari malformation and Joubert syndrome), achondroplasia, and mucopolysaccharidosis. OSAS may affect the executive functioning such as motivational ability, planning, behavior modulation, ability to complete an action program, identification of functional strategies to achieve the goal, problem solving, flexibility, monitoring and self-assessment of behavior in relation to results, change of task, or behavior in the light of emerging information, which may be all impaired by nocturnal intermittent hypoxia also during the developmental age. The clinical presentation of OSAS can mimic other neurobehavioral symptoms, such as ADHD syndrome, learning problems, or can exacerbate the Fragile X syndrome, and generalized non-convulsive epilepsy symptoms.

Published
2022

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