750 results on '"Carotenuto, M"'
Search Results
2. A holistic picture of spatial distribution of river polluting loads in a highly anthropized area
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Lofrano, G., Serafini, S., Saviano, L., Carotenuto, M., Guida, M., Romano Spica, V., Cardito, A., and Libralato, G.
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- 2023
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3. Thirty contaminants of emerging concern identified in secondary treated hospital wastewater and their removal by solar Fenton (like) and sulphate radicals-based advanced oxidation processes
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Lofrano, G., Faiella, M., Carotenuto, M., Murgolo, S., Mascolo, G., Pucci, L., and Rizzo, L.
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- 2021
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4. Aerobic Exercise and Metabolic Syndrome: The Role of Sympathetic Activity and the Redox System
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Monda V, Sessa F, Ruberto M, Carotenuto M, Marsala G, Monda M, Cambria MT, Astuto M, Distefano A, and Messina G
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metabolic syndrome (mets) ,orexin a ,body mass index (bmi) ,heart rate (hr) ,cholesterol ,physical activity ,Specialties of internal medicine ,RC581-951 - Abstract
Vincenzo Monda,1 Francesco Sessa,2 Maria Ruberto,3 Marco Carotenuto,4 Gabriella Marsala,5 Marcellino Monda,1 Maria Teresa Cambria,6 Marinella Astuto,7 Alfio Distefano,6 Giovanni Messina2 1Department of Experimental Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Caserta 81100, Italy; 2Department of Clinical and Experimental Medicine, University of Foggia, Foggia 71121, Italy; 3CDR Santa Maria del Pozzo, Naples 80049, Italy; 4Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Caserta 81100, Italy; 5Struttura Complessa di Farmacia, Azienda Ospedaliero-Universitaria, Ospedali Riuniti di Foggia, Foggia 71121, Italy; 6Section of Medical Biochemistry, Department of Biomedical and Biotechnological Sciences, University of Catania, Catania 95123, Italy; 7Azienda Ospedaliera “Policlinico Vittorio Emanuele”, U.O. di Anestesia e Terapia Intensiva, Catania 95123, ItalyCorrespondence: Francesco SessaDepartment of Clinical and Experimental Medicine, University of Foggia, Foggia 71122, ItalyTel +39 0881 736926Email francesco.sessa@unifg.itBackground: Aerobic exercise can greatly assist in reducing collateral effects of metabolic syndrome (MetS). Moreover, aerobic exercise is associated with sympathetic activation and adaptive responses to sustain muscle engagement, changes in the release of Orexin A, a pleiotropic neuropeptide.Aim: The aim of this study was to analyze the beneficial effects of aerobic exercise without dietary changes, in a cohort of MetS subjects, focusing on the role of sympathetic and orexinergic activity. Several blood parameters linked to MetS ROS production, heart rate, galvanic skin response, d-ROM test, and Orexin A serum levels were evaluated in ten males with MetS (BMI 30– 34.9) before and after a period of 6 months of aerobic exercise compared to ten healthy subjects.Methods: Ten male subjects (aged 54 ± 4.16) with MetS (MetS group) and ten healthy males (aged 49.7 ± 2.79, Healthy group) were told about the study protocol and possible risks, signed the informed consent, and voluntarily participated in the study. Several blood parameters were evaluated in the two tested groups and were re-evaluated in the MetS group after 6 months of training (MetS6M group). The training protocol consisted of more than 30 min/day of walking (average speed of 4.5 km/h) and 3 days/week of aerobic activities (jogging under heart rate control – 120– 140 bpm for 45 min).Results: The results showed that exercise induced a significant increase in GSR and plasma Orexin A but no significant increase in d-ROM values. Significant decreases in the serum ALT enzyme, triglycerides, and total cholesterol were found, while the HDL levels were significantly higher. Finally, a significant reduction of BMI and resting HR were reported.Conclusion: The results of this study confirm that physical activity is associated with sympathetic activation, having a pivotal role against adverse effects linked to MetS. Moreover, this study demonstrates that, in patients with MetS, Orexin A is involved in hormonal adaptations to exercise.Keywords: metabolic syndrome, MetS, Orexin A, body mass index, BMI, heart rate, HR, cholesterol, physical activity
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- 2020
5. Memory performances and personality traits in mothers of children with obstructive sleep apnea syndrome
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Smirni D, Carotenuto M, Precenzano F, Smirni P, Operto FF, Marotta R, and Roccella M
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parental stress ,memory performances ,self-esteem ,locus of control ,Psychology ,BF1-990 ,Industrial psychology ,HF5548.7-5548.85 - Abstract
Daniela Smirni*,1, Marco Carotenuto*,2, Francesco Precenzano,2 Pietro Smirni,3 Francesca Felicia Operto,4 Rosa Marotta,5 Michele Roccella11Department of Psychology, Educational Science and Human Movement, University of Palermo, Palermo, Italy; 2Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Università Degli Studi Della Campania “Luigi Vanvitelli”, Naples, Italy; 3Department of Educational Sciences, University of Catania, Catania, Italy; 4Child Neuropsychiatry Unit, Department of Basic Medical Sciences, Neuroscience and Sense Organs, University of Bari Aldo Moro, Bari, Italy; 5Department of Health Sciences, University “Magna Graecia”, Catanzaro, Italy*These authors contributed equally to this workBackground: Chronic diseases in pediatric age have been identified as stressful risk factors for parents. Studies on caregivers have documented the impact of chronic parenting stress on emotion and cognition.Aim: To investigate the differences between a group of mothers of children affected by obstructive sleep apnea syndrome (OSAS) for at least 4 years and a group of mothers of typically developing children (TDC) in relation to parental stress, self-esteem, locus of control, and memory performances.Methods: A group of 86 mothers (mean age 35.6±4.9, ranged between 32 and 41 years) of children with OSAS diagnosis, and a group of 52 mothers of TDC (mean age 35.9±4.2, ranged between 32 and 41 years) participated in the study. All participants were administered stress level, global self-esteem, internal/external locus of control scales, and memory assessment.Results: Mothers of OSAS children, compared to mothers of TDC, had a significantly higher level of stress, lower self-esteem, more external locus of control and poorer memory performance.Conclusions: The child respiratory disease, with its sudden and unpredictable features, appeared as a significant source of stress for the mother. Such stress condition may have an impact on mothers’ personality traits (self-esteem, locus of control) and on their memory performances. The data have suggested a need for psychological support programs for mothers to better manage stress associated with children’s respiratory disease.Keywords: parental stress, memory performances, self-esteem, locus of control
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- 2019
6. Understanding and Optimizing Peracetic Acid Disinfection Processes Using Computational Fluid Dynamics: The Case Study of Nocera (Italy) Wastewater Treatment Plant
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Maffettone, R., Crapulli, F., Sarathy, S., Pucci, L., Rizzo, L., Lofrano, G., Raspa, G., Guadagnuolo, S., De Rosa, R., Giuliani, A., Carotenuto, M., Luise, S., Santoro, D., di Prisco, Marco, Series editor, Chen, Sheng-Hong, Series editor, Solari, Giovanni, Series editor, Vayas, Ioannis, Series editor, and Mannina, Giorgio, editor
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- 2017
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7. Analysis and Optimization of Energy Consumption in Relation to GHG Management: The Case Study of Medio Sarno Wastewater Treatment Plant
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Falcone, A., Pucci, L., Guadagnuolo, S., De Rosa, R., Giuliani, A., d’Antoni, B. M., Lofrano, G., Libralato, G., Fatone, F., Carotenuto, M., di Prisco, Marco, Series editor, Chen, Sheng-Hong, Series editor, Solari, Giovanni, Series editor, Vayas, Ioannis, Series editor, and Mannina, Giorgio, editor
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- 2017
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8. Brain functional integration: an epidemiologic study on stress-producing dissociative phenomena
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Sperandeo R, Monda V, Messina G, Carotenuto M, Maldonato NM, Moretto E, Leone E, De Luca V, Monda M, and Messina A
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mental disorders ,personality disorders ,amnesia ,depersonalization/derealization ,Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Raffaele Sperandeo,1,2,* Vincenzo Monda,3,* Giovanni Messina,4 Marco Carotenuto,5 Nelson Mauro Maldonato,1,2 Enrico Moretto,1,2 Elena Leone,1,2 Vincenzo De Luca,6 Marcellino Monda,3 Antonietta Messina3 1Department of Human Sciences, Università Della, Basilicata, 2School of Integrated Gestaltic Psychotherapy, Torre Annunziata, 3Department of Experimental Medicine, Section of Human Physiology and Unit of Dietetic and Sport Medicine, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, 4Department of Clinical and Experimental Medicine, University of Foggia, Foggia, 5Department of Mental Health, Physical and Preventive Medicine, Clinic of Child and Adolescent Neuropsychiatry, Università degli Studi della Campania “Luigi Vanvitelli”, Naples, Italy; 6Department of Psychiatry, University of Toronto, Toronto, Canada *These authors contributed equally to this work Abstract: Dissociative phenomena are common among psychiatric patients; the presence of these symptoms can worsen the prognosis, increasing the severity of their clinical conditions and exposing them to increased risk of suicidal behavior. Personality disorders as long duration stressful experiences may support the development of dissociative phenomena. In 933 psychiatric outpatients consecutively recruited, presence of dissociative phenomena was identified with the Dissociative Experience Scale (DES). Dissociative phenomena were significantly more severe in the group of people with mental disorders and/or personality disorders. All psychopathologic traits detected with the symptom checklist-90-revised had a significant correlation with the total score on the DES. Using total DES score as the dependent variable, a linear regression model was constructed. Mental and personality disorders which were associated with greater severity of dissociative phenomena on analysis of variance were included as predictors; scores from the nine scales of symptom checklist-90-revised, significantly correlated to total DES score, were used as covariates. The model consisted of seven explanatory variables (four factors and three covariates) explaining 82% of variance. The four significant factors were the presence of borderline and narcissistic personality disorder, substance abuse disorders and psychotic disorders. Significant covariates were psychopathologic traits of anger, psychoticism and obsessiveness. This study, confirming Janet’s theory, explains that, mental disorders and psychopathologic experiences of patients can configure the chronic stress condition that produces functional damage to the adaptive executive system. The symptoms of dissociative depersonalization/derealization and dissociative amnesia can be explained, in large part, through their current and previous psychopathologic experiences. Keywords: mental disorders, personality disorders, amnesia, depersonalization/derealization
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- 2017
9. Obesity and brain illness: from cognitive and psychological evidences to obesity paradox
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Monda V, La Marra M, Perrella R, Caviglia G, Iavarone A, Chieffi S, Messina G, Carotenuto M, Monda M, and Messina A
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Obesity ,Cognitive decline ,Mood disorders ,Obesity paradox ,Specialties of internal medicine ,RC581-951 - Abstract
Vincenzo Monda,1,* Marco La Marra,1,* Raffaella Perrella,2 Giorgio Caviglia,2 Alessandro Iavarone,3 Sergio Chieffi,1 Giovanni Messina,4 Marco Carotenuto,5 Marcellino Monda,1 Antonietta Messina1 1Department of Experimental Medicine, Section of Human Physiology, University of Campania Luigi Vanvitelli, Naples, Italy; 2Neurological and Stroke Unit, CTO Hospital, AORN ‘‘Ospedali dei Colli’’, Naples, Italy; 3Department of Psychology, University of Campania Luigi Vanvitelli, Naples, Italy; 4Department of Clinical and Experimental Medicine, University of Foggia, Foggia, Italy; 5Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, University of Campania Luigi Vanvitelli, Naples, Italy *These authors contributed equally to this work Abstract: Recent findings showed that obesity represents an additional risk factor to developing brain illness such as cognitive impairments and psychopathological disorders. However, some benefits of overweight in the elderly have been identified and an “obesity paradox” has been shown. Currently, it is still unknown how obesity and brain functioning could be linked, and the process by which body fat independently injures cognitive abilities and psychological well-being remains unclear. To establish the independent role of obesity on cognitive abilities and mental health, clarifying the role played by several factors and understanding their interaction is essential. In this review, we discuss the relationship between obesity and brain illness and underline the role played by confounders and other covariates to determine this link. Keywords: obesity, cognitive decline, mood disorders, obesity paradox
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- 2017
10. Bigorexia and orthorexia: an indissoluble relationship?
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Parisi L., Lagrutta S., Baido R. L., Epifanio M. S., Carotenuto M., Operto F. F., Testa D., Vetri L., Roccella M., Parisi L., La Grutta S., Lo Baido R., Epifanio M.S., Carotenuto M., Operto F.F., Testa D., Vetri L., Roccella M., Parisi, L., Lagrutta, S., Baido, R. L., Epifanio, M. S., Carotenuto, M., Operto, F. F., Testa, D., Vetri, L., and Roccella, M.
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Psychiatry ,Psychiatry and Mental health ,Body dysmorphic disorder ,Body dysmorphic disorders ,Feeding and eating disorder ,Feeding and eating disorders - Abstract
BACKGROUND: Bigorexia or muscle dysmorphia (MD) is a subtype of body dysmorphic disorder, and it is characterized by an excessive dissatisfaction with body size and muscularity. Orthorexia nervosa (ON) is an obsessive focus on healthy eating and emotional distress related to food choices that are perceived as unhealthy. MD and ON are considered two emerging psychiatric disorders. METHODS: The aim of this study was to evaluate the prevalence of traits of ON and MD between amateurs and professional athletes who practice bodybuilding. The secondary endpoint of the study is to identify the anabolic steroid abuse among the athletes. To this end we have administered a dichotomic questionnaire to 60 young men: 30 amateur bodybuilders (ABBs) and 30 professional bodybuilders (PBBs). RESULTS: Scores compatible with a full-blown MD disorder have been found in 100% of subjects of PBB group and in 83% of ABB group. Afull-blown ON has been detected in 87% of BBPs and 40% of BBAs and a risk for ON in 10% of BBPs and in 37% of BBAs. CONCLUSIONS: This study shows a high co-occurrence of MD and ON among the bodybuilders suggesting a link between eating disorders and body dysmorphic disorders.
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- 2022
11. Microplastics and recreational water
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Lofrano, G., Albarano, L., Valeriani, F., Bellino, A., Ubaldi, F., Libralato, G., Carotenuto, M., Baldantoni, D., Guida, M., and Romano Spica, V.
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- 2023
12. Sleep macrostructure in adolescents with Anorexia Nervosa: A pilot case-control study
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Carotenuto, M., primary, Precenzano, F., additional, Gleijeses, M.G., additional, Siciliano, M., additional, Silvestri, F., additional, Sabatino, M., additional, Panico, F., additional, and Salerno, F., additional
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- 2022
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13. Mortality in Covid-19 patients hospitalized in a teaching hospital in Italy during the first 3 waves
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Bertolotti, M, primary, Betti, M, additional, Ferrante, D, additional, Giacchero, F, additional, Odone, A, additional, Franceschetti, G, additional, Carotenuto, M, additional, Pacileo, G, additional, and Maconi, A, additional
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- 2022
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14. Intellectual Disabilities and Power Spectra Analysis during Sleep: A New Perspective on Borderline Intellectual Functioning
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Esposito, M. and Carotenuto, M.
- Abstract
Background: The role of sleep in cognitive processes has been confirmed by a growing number of reports for all ages of life. Analysing sleep electroencephalogram (EEG) spectra may be useful to study cortical organisation in individuals with Borderline Intellectual Functioning (BIF), as seen in other disturbances even if it is not considered a disease. The aim of this study was to determine if the sleep EEG power spectra in children with BIF could be different from typically developing children. Methods: Eighteen BIF (12 males) (mean age 11.04; SD?±?1.07) and 24 typical developing children (14 men) (mean age 10.98; SD?±?1.76; "P"?=?0.899) underwent an overnight polysomnography (PSG) recording in the Sleep Laboratory of the Clinic of Child and Adolescent Neuropsychiatry, after one adaptation night. Sleep was subdivided into 30-s epochs and sleep stages were scored according to the standard criteria and the power spectra were calculated for the Cz-A2 channel using the sleep analysis software Hypnolab 1.2 (SWS Soft, Italy) by means of the Fast Fourier Transform and the power spectrum was calculated for frequencies between 0.5 and 60?Hz with a frequency step of 1?Hz and then averaged across the following bands delta (0.5-4?Hz), theta (5-7?Hz), alpha (8-11?Hz), sigma (11-15?Hz), and beta (16-30?Hz), gamma (30-60?Hz) for S2, SWS and REM (Rapid Eye Movement) sleep stages. Results: BIF have a reduced sleep duration (total sleep time; P"?0.001), and an increased rate of stage shifts ("P"?0.001) and awakenings ("P"?0.001) and WASO (wakefulness after sleep onset) % ("P"?0.001); the stage 2% ("P"?0.001), and REM% ("P"?0.001) were lower and slow-wave sleep percentage was slightly higher ("P"?0.001). All children with BIF had an AHI (apnoea-hypopnea index) less than 1 (mean AHI?=?0.691?±?0.236) with a mean oxygen saturation of 97.6% and a periodic leg movement index (PLMI) less than 5 (mean PLMI?=?2.94?±?1.56). All sleep stages had a significant reduction in gamma frequency (30-60?Hz) ("P"?0.001) and an increased delta frequency (0.5-4.0?Hz) ("P"?0.001) power in BIF subjects compared with typically developing children. Conclusion: Our findings shed light on the importance of sleep for cognition processes particularly in cognitive borderline dysfunction and the role of EEG spectral power analysis to recognize sleep characteristics in BIF children.
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- 2014
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15. Emerging Concern from Short-Term Textile Leaching: A Preliminary Ecotoxicological Survey
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Lofrano, G., Libralato, G., Carotenuto, M., Guida, M., Inglese, M., Siciliano, A., and Meriç, S.
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- 2016
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16. Anxiety and depression levels in prepubertal obese children: a case-control study
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Esposito M, Gallai B, Roccella M, Marotta R, Lavano F, Lavano SM, Mazzotta G, Bove D, Sorrentino M, Precenzano F, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Beatrice Gallai,2 Michele Roccella,3 Rosa Marotta,4 Francesco Lavano,4 Serena Marianna Lavano,4 Giovanni Mazzotta,5 Domenico Bove,6 Michele Sorrentino,1 Francesco Precenzano,1 Marco Carotenuto1 1Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 3Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 4Department of Psychiatry, “Magna Graecia” University of Catanzaro, Catanzaro, Italy; 5Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria 2, Terni, Italy; 6Centro per la Diagnosi e Cura dei Disturbi dell’apprendimento e del Comportamento Associazione per la ricerca scientifica Fusis, Alvignano, Italy Introduction: Childhood obesity has become a worldwide epidemic in Western and in developing countries and has been accompanied by many serious and severe comorbidities, such as diabetes, hypertension, sleep apnea syndrome, depression, dyslipidemia, impaired glucose homeostasis, steatohepatitis, and intracranial hypertension, as well as medical concerns unique to youth, such as accelerated pubertal and skeletal development and orthopedic disorders. To date, no specific studies about the psychological assessment in pediatric obesity are present. Therefore, the aim of this study was to evaluate the putative relationship between psychological troubles and obesity in a sample of school-aged children. Materials and methods: The study population consists of 148 obese subjects (body mass index [BMI] >95th percentile) (69 males, mean age 8.9±1.23 years) consecutively referred from clinical pediatricians to the Child and Adolescent Neuropsychiatry department at the Second University of Naples. In all subjects, weight, height, and BMI z-score were evaluated. In order to assess the anxiety levels and the presence of depressive symptoms, the Children Depression Inventory (CDI) and the Italian Self-Administered Psychiatric Scales for Children and Adolescents (SAFA) were administered. The control group consisted of 273 healthy children (129 males and 144 females) (mean age 9.1±1.8 years), enrolled in schools within the Campania region of Italy. Results: No significant differences between the two study groups were found for age (8.9±1.23 years in the obese sample and 9.1±1.8 years in the control group) (P=0.228) or sex (ratio male/female: 69/79 in the obese group versus 129/144 in the control group) (P=0.983). Obviously, significant difference was found for the BMI z-score (2.46±0.31 in the obese group vs 0.73±0.51 in the control group) (P
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- 2014
17. Orthodontic treatment need for adolescents in the Campania region: the malocclusion impact on self-concept
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Perillo L, Esposito M, Caprioglio A, Attanasio S, Santini AC, and Carotenuto M
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Medicine (General) ,R5-920 - Abstract
Letizia Perillo,1 Maria Esposito,2 Alberto Caprioglio,3 Stefania Attanasio,1 Annamaria Chiara Santini,2 Marco Carotenuto2 1Department of Orthodontics, Second University of Naples, Naples, Italy; 2Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 3Department of Orthodontics, University of Insubria, Varese, Italy Background: Dental malocclusions can be considered not only as an oral health problem, because they are linked to quality of life perception. Many factors related to malocclusion have strong influences on the perception of facial esthetics (eg, anterior tooth alignment, tooth shape and position, lip thickness, symmetric gingival or tooth contour, lip profile, and overjet). Many reports have shown that the perception of facial esthetics can influence psychological development from early childhood to adulthood. The aim of this study is to investigate the effect of dental malocclusion on self-esteem in a sample of adolescents. Materials and methods: The study population was composed of 516 orthodontically untreated subjects (256 males) mean ages 13.75±1.977 years recruited from schools in the Campania region of Italy between January 2011 and July 2011. To evaluate the self-esteem grade in our population, all subjects filled out the Multidimensional Self Concept Scale questionnaire and attended an orthodontic clinical evaluation to estimate dental occlusal aspects. Results: Pearson's analysis shows the relationship in our sample between some occlusal characteristics (crossbite and dental crowding) and aspects of self-concept evaluation (social, competence, academic, physical, and global score) of the Multidimensional Self Concept Scale questionnaire. Moreover, logistic regression analysis shows the potential role of dental crowding (odds ratio 5.359; 95% confidence interval 3.492–8.225) and crossbite (odds ratio 6.153; 95% confidence interval 3.545–10.678) as risk factors for development of global self-concept score abnormalities. Conclusion: Our findings confirm the relationship between psychosocial well-being, self-esteem, and dental malocclusion among adolescents. Keywords: dental malocclusion, self-concept, adolescents, crossbite, dental crowding
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- 2014
18. Analysis of PAHs (polycyclic aromatic hydrocarbons) and other main components in black crusts collected from the Monumental Cemetery of Milan (Italy)
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Ricciardi, M., primary, Faggiano, A., additional, Pironti, C., additional, Motta, O., additional, Carotenuto, M., additional, Comite, V., additional, Fermo, P., additional, and Proto, A., additional
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- 2022
- Full Text
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19. Effectiveness and safety of Nintendo Wii Fit PlusTM training in children with migraine without aura: a preliminary study
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Esposito M, Ruberto M, Gimigliano F, Marotta R, Gallai B, Parisi L, Lavano SM, Roccella M, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Maria Ruberto,2 Francesca Gimigliano,1,2 Rosa Marotta,3 Beatrice Gallai,4 Lucia Parisi,5 Serena Marianna Lavano,3 Michele Roccella,5 Marco Carotenuto11Center for Childhood Headache, Child and Adolescent Neuropsychiatry Clinic, Department of Mental Health, Physical and Preventive Medicine, 2Department of Odonto-Stomathologic Disciplines, Pathology – Orthopedic Sciences, Second University of Naples, Naples, Italy; 3Department of Psychiatry, “Magna Graecia” University of Catanzaro, Catanzaro, Italy; 4Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 5Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, ItalyBackground: Migraine without aura (MoA) is a painful syndrome, particularly in childhood; it is often accompanied by severe impairments, including emotional dysfunction, absenteeism from school, and poor academic performance, as well as issues relating to poor cognitive function, sleep habits, and motor coordination.Materials and methods: The study population consisted of 71 patients affected by MoA (32 females, 39 males) (mean age: 9.13±1.94 years); the control group consisted of 93 normally developing children (44 females, 49 males) (mean age: 8.97±2.03 years) recruited in the Campania school region. The entire population underwent a clinical evaluation to assess total intelligence quotient level, visual-motor integration (VMI) skills, and motor coordination performance, the later using the Movement Assessment Battery for Children (M-ABC). Children underwent training using the Wii-balance board and Nintendo Wii Fit Plus™ software (Nintendo Co, Ltd, Kyoto, Japan); training lasted for 12 weeks and consisted of three 30-minute sessions per week at their home.Results: The two starting populations (MoA and controls) were not significantly different for age (P=0.899) and sex (P=0.611). M-ABC and VMI performances at baseline (T0) were significantly different in dexterity, balance, and total score for M-ABC (P
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- 2013
20. Attachment styles in children affected by migraine without aura
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Esposito M, Parisi L, Gallai B, Marotta R, Di Dona A, Lavano SM, Roccella M, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Lucia Parisi,2 Beatrice Gallai,3 Rosa Marotta,4 Anna Di Dona,1 Serena Marianna Lavano,2 Michele Roccella,4 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 4Department of Psychiatry, The Magna Graecia University of Catanzaro, Catanzaro, ItalyBackground: In recent years, great attention has been given to the presence of psychological problems and psychiatric comorbidity that are also present in children affected by primary headaches. The relationship between pain and attachment has been identified, and it may be that pain perception may change in relation with specific attachment styles. The aim of the present study was to assess the prevalent attachment style and verify its putative relationship and correlation with the main characteristics of migraine attacks, in school-aged children affected by migraine without aura (MoA).Materials and methods: The study population consisted of 219 children (103 males, 116 females) aged between 6 and 11 years (mean 8.96 ± 2.14 years), consecutively referred for MoA compared with 381 healthy controls (174 males, 207 females; mean age 9.01 ± 1.75 years) randomly selected from schools. All the children were classified according to the attachment typologies of the Italian modified version of the Separation Anxiety Test; monthly headache frequency and mean headache duration were assessed from daily headache diaries kept by all the children. Headache intensity was assessed on a visual analogue scale. The chi-square test and t-test, where appropriate, were applied, and the Spearman rank correlation test was applied to explore the relationship between the types of attachment style and clinical aspects of MoA.Results: The MoA group showed a significantly higher prevalence of type A (avoidant) attachment (P
- Published
- 2013
21. Correction:Role of Vitamin E and the Orexin System in Neuroprotection(Brain Sci., (2021), 11, (1098), 10.3390/brainsci11081098)
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La Torre, M. E., Villano, I., Monda, M., Messina, A., Cibelli, G., Valenzano, A., Pisanelli, D., Panaro, M. A., Tartaglia, N., Ambrosi, A., Carotenuto, M., Monda, V., Messina, G., and Porro, C.
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- 2022
22. Exome sequencing in a child with neurodevelopmental disorder and epilepsy:variant analysis of the AHNAK2 gene
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Vinci, M. (Mirella), Kursula, P. (Petri), Greco, D. (Donatella), Elia, M. (Maurizio), Vetri, L. (Luigi), Schepis, C. (Carmelo), Chiavetta, V. (Valeria), Donadio, S. (Serena), Roccella, M. (Michele), Carotenuto, M. (Marco), Romano, V. (Valentino), and Calì, F. (Francesco)
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facio-cardio-cutaneous-like phenotype ,AHNAK2 ,borderline intellectual functioning ,epilepsy ,NGS exome - Abstract
Background/Objectives: The AHNAK2 gene encodes a large nucleoprotein expressed in several tissues, including brain, squamous epithelia, smooth muscle, and neuropil. Its role in calcium signaling has been suggested and to date, clear evidence about its involvement in the pathogenesis of clinical disorders is still lacking. Methods: Here, we report a female 24-year-old patient diagnosed with a cardio-facio-cutaneous-like phenotype (CFC-like), characterized by epilepsy, psychomotor development delay, atopic dermatitis, congenital heart disease, hypotonia, and facial dysmorphism, who is compound heterozygote for two missense mutations in the AHNAK2 gene detected by exome sequencing. Results: This patient had no detectable variant in any of the genes known to be associated with the cardio-facio-cutaneous syndrome. Moreover, the mode of inheritance does not appear to be autosomal dominant, as it is in typical CFC syndrome. We have performed in silico assessment of mutation severity separately for each missense mutation, but this analysis excludes a severe effect on protein function. Protein structure predictions indicate the mutations are located in flexible regions possibly involved in molecular interactions. Conclusions: We discuss an alternative interpretation on the potential involvement of the two missense mutations in the AHNAK2 gene on the expression of CFC-like phenotype in this patient based on inter-allelic complementation.
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- 2022
23. Using virtual reality to improve learning in children with ADHD
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Frolli, A, Ricci, Mc, Di Carmine, F, Savarese, G, Siciliano, M, Carotenuto, M, and Rega, A
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Attention deficit hyperactivity disorder ,Virtual reality, Attention deficit hyperactivity disorder, Children, Learning, Motivation, Embodied cognition ,Motivation ,Learning ,Children ,Virtual reality ,Embodied cognition - Published
- 2022
24. Nocturnal obstructive respiratory events severity is associated with low parental quality
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Marotta, R., Precenzano, F., Operto, F. F., Lanzara, V., Risoleo, M. C., Vetri, L., Parisi, L., Pastorino, G. M. G., Gallai, B., Scarinci, A., Gleijeses, M. G., Solimeno, M., Merolla, E., Sabatino, M., Messina, G., Giuseppina Marcuccio, Carotenuto, M., Roccella, M., Marotta R., Precenzano F., Operto F.F., Lanzara V., Risoleo M.C., Vetri L., Parisi L., Pastorino G.M.G., Gallai B., Scarinci A., Gleijeses M.G., Solimeno M., Merolla E., Sabatino M., Messina G., Marcuccio G., Carotenuto M., Roccella M., Marotta, R., Precenzano, F., Operto, F. F., Lanzara, V., Risoleo, M. C., Vetri, L., Parisi, L., Pastorino, G. M. G., Gallai, B., Scarinci, A., Gleijeses, M. G., Solimeno, M., Merolla, E., Sabatino, M., Messina, G., Marcuccio, G., Carotenuto, M., and Roccella, M.
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Coping strategies ,Coping strategie ,Caregiver stress ,Caregiver stre ,Nocturnal respiratory troubles ,Caregiver stress, Coping strategies, Nocturnal respiratory troubles - Abstract
Objective: Despite of the large prevalence of obstructive sleep apnea syndrome (OSAS) in pediatric age, numerous aspects of its impact on day life and on parental quality are still poor studied and considered in the clinical management. The study evaluated the stress levels and copying styles in a large sample of mother of children with OSAS. Method: 374 mothers of children affected by OSAS (mOSAS) were compared with a group of mothers of 421 neurotypical healthy children (mTDC) for stress perceived stress levels and for coping strategies. Subjects were recruited from Italian Regions in Sicily, Campania, Calabria and Umbria. Results: Among both groups mOSAS and mTDC no differences were reported for children age (p=0.340), children gender (p=0.956), similarly for age of mothers (p=0.188). Discussion: The perceived stress assessment in mOSAS showed higher rate of all parental stress scores of PSI-SF: Parental Distress domain (p
- Published
- 2020
25. Psychomotor approach in children affected by nonretentive fecal soiling (FNRFS): a new rehabilitative purpose
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Esposito M, Gimigliano F, Ruberto M, Marotta R, Gallai B, Parisi L, Lavano SM, Mazzotta G, Roccella M, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Francesca Gimigliano,1,2 Maria Ruberto,2 Rosa Marotta,3 Beatrice Gallai,4 Lucia Parisi,5 Serena Marianna Lavano,3 Giovanni Mazzotta,6 Michele Roccella,5 Marco Carotenuto1 1Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Department of Odontostomathologic Disciplines, Head Pathology, Orthopedic Sciences, Second University of Naples, Italy; 3Department of Psychiatry, Magna Graecia University of Catanzaro, Catanzaro, Italy; 4Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 5Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 6Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria, Terni, Italy Background: According to the Rome III criteria, encopresis without constipation was defined as nonretentive fecal soiling (FNRFS) with not yet well understood etiology. Treatment approaches reported in the literature with varying results include biofeedback, hypnosis, reflexology, and Internet-based educational programs. In developmental age, another behavioral treatment could be identified in the psychomotor approach, which is called psychomotricity in the European countries, or is also known as play therapy. The aim of the present study was to verify the safety and efficacy of play therapy plus toilet training in a small sample of prepubertal children affected by FNRFS. Materials and methods: Twenty-six patients (group 1; 16 males, mean age of 5.92 ± 0.84 years) underwent a psychomotor approach therapy program in association with toilet training for 6 months, and the other 26 subjects (group 2; 17 males, mean age of 5.76 ± 0.69) underwent the sole toilet training program for 6 months. During the observational time period (T0) and after 6 months (T1) of both treatments, the patients were evaluated for FNRFS frequency and for the behavioral assessment. Results: At T0, the FNRFS mean frequency per month for group 1 was 20.115 episodes/month (standard deviation [SD] ± 3.024) and for group 2 was 20.423 (SD ± 1.879) (P = 0.661). At T1 the mean frequency per month was 6.461 (SD ± 1.333) episodes/month and 12.038 (SD ± 1.341), respectively (P < 0.001). Moreover, the delta percent average of the frequency between T0 and T1 was 67.121 ± 8.527 for group 1 and 40.518 ± 9.259 for group 2 (P < 0.001). At T1, a significant improvement in scores on the behavioral scale was identified. Conclusion: Our preliminary results show the importance of a multidisciplinary approach, and suggest the positive effect of an additional psychomotor approach, as this holds a new and interesting rehabilitative purpose for children in a toilet training program, even if further research is necessary. Keyword: encopresis, psychomotricity, children, toilet training, rehabilitation
- Published
- 2013
26. Maternal personality profile of children affected by migraine
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Esposito M, Roccella M, Gallai B, Parisi L, Lavano SM, Marotta R, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Michele Roccella,2 Beatrice Gallai,3 Lucia Parisi,2 Serena Marianna Lavano,4 Rosa Marotta,4 Marco Carotenuto1 1Center for Childhood Headache, Second University of Naples, Naples, Italy; 2Department of Psychology, University of Palermo, Palermo, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 4Department of Psychiatry, Magna Graecia University of Catanzaro, Catanzaro, Italy Background: Empirical evidence of the important role of the family in primary pediatric headache has grown significantly in the last few years, although the interconnections between the dysfunctional process and the family interaction are still unclear. Even though the role of parenting in childhood migraine is well known, no studies about the personality of parents of migraine children have been conducted. The aim of the present study was to assess, using an objective measure, the personality profile of mothers of children affected by migraine without aura (MoA). Materials and methods: A total of 269 mothers of MoA children (153 male, 116 female, aged between 6 and 12 years; mean 8.93 ± 3.57 years) were compared with the findings obtained from a sample of mothers of 587 healthy children (316 male, 271 female, mean age 8.74 ± 3.57 years) randomly selected from schools in the Campania, Umbria, Calabria, and Sicily regions. Each mother filled out the Minnesota Multiphasic Personality Inventory – second edition (MMPI-2), widely used to diagnose personality and psychological disorders. The t-test was used to compare age and MMPI-2 clinical basic and content scales between mothers of MoA and typical developing children, and Pearson’s correlation test was used to evaluate the relation between MMPI-2 scores of mothers of MoA children and frequency, intensity, and duration of migraine attacks of their children. Results: Mothers of MoA children showed significantly higher scores in the paranoia and social introversion clinical basic subscales, and in the anxiety, obsessiveness, depression, health concerns, bizarre mentation, cynicism, type A, low self-esteem, work interference, and negative treatment indicator clinical content subscales (P < 0.001 for all variables). Moreover, Pearson’s correlation analysis showed a significant relationship between MoA frequency of children and anxiety (r = 0.4903, P = 0.024) and low self-esteem (r = 0.5130, P = 0.017), while the MoA duration of children was related with hypochondriasis (r = 0.6155, P = 0.003), hysteria (r = 0.6235, P = 0.003), paranoia (r = 0.5102, P = 0.018), psychasthenia (r = 0.4806, P = 0.027), schizophrenia (r = 0.4350, P = 0.049), anxiety (r = 0.4332, P = 0.050), and health concerns (r = 0.7039, P < 0.001) MMPI-2 scores of their mothers. Conclusion: This could be considered a preliminary study that indicates the potential value of maternal personality assessment for better comprehension and clinical management of children affected by migraine, though further studies on the other primary headaches are necessary. Keywords: MMPI-2, childhood migraine, maternal personality
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- 2013
27. Executive dysfunction in children affected by obstructive sleep apnea syndrome: an observational study
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Esposito M, Antinolfi L, Gallai B, Parisi L, Roccella M, Marotta R, Lavano SM, Mazzotta G, Precenzano F, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Lorenzo Antinolfi,1 Beatrice Gallai,2 Lucia Parisi,3 Michele Roccella,3 Rosa Marotta,4 Serena Marianna Lavano,4 Giovanni Mazzotta,5 Francesco Precenzano,1 Marco Carotenuto1 1Sleep Clinic for Developmental Age, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental and Physical Health and Preventive Medicine, Second University of Naples, Naples, Italy; 2Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 3Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 4Department of Psychiatry, Magna Graecia University of Catanzaro, Catanzaro, Italy; 5Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria 2, Terni, Italy Introduction: The role of sleep in cognitive processes can be considered clear and well established. Different reports have disclosed the association between sleep and cognition in adults and in children, as well as the impact of disturbed sleep on various aspects of neuropsychological functioning and behavior in children and adolescents. Behavioral and cognitive dysfunctions can also be considered as related to alterations in the executive functions (EF) system. In particular, the EF concept refers to self-regulatory cognitive processes that are associated with monitoring and controlling both thought and goal directed behaviors. The aim of the present study is to assess the impact of the obstructive sleep apnea syndrome (OSAS) on EF in a large sample of school aged children. Materials and methods: The study population comprised 79 children (51 males and 28 females) aged 7–12 years (mean 9.14 ± 2.36 years) with OSAS and 92 healthy children (63 males and 29 females, mean age 9.08 ± 2.44 years). To identify the severity of OSAS, an overnight respiratory evaluation was performed. All subjects filled out the Italian version of the Modified Card Sorting Test to screen EFs. Moreover, to check the degree of subjective perceived daytime sleepiness, all subjects were administered the Pediatric Daytime Sleepiness Scale (PDSS). Results: No significant differences between the two study groups were found for age (P = 0.871), gender (P = 0.704), z-score of body mass index (P = 0.656), total intelligence quotient (P = 0.358), and PDSS scores (P = 0.232). The OSAS children showed a significantly higher rate of total errors (P < 0.001), perseverative errors (P < 0.001), nonperseverative errors (P < 0.001), percentage of total errors (P < 0.001), percentage of perseverative errors (P < 0.001), and percentage of nonperseverative errors (P< 0.001). On the other hand, OSAS children showed a significant reduction in the number of completed categories (P = 0.036), total correct sorts (P = 0.001), and categorizing efficiency (P < 0.001). The Pearson's correlation analysis revealed a significant positive relationship between all error parameters and apnea-hypopnea index, oxygen desaturation index, and percentage of mean desaturation of O2 with a specular negative relationship between the error parameters and the mean oxygen saturation values, such as a significant negative relationship between apnea-hypopnea index, oxygen desaturation index, percent of mean desaturation of O2, and the number of completed categories. Conclusion: Our study identified differences in the executive functioning of children affected by OSAS and is the first to identify a correlation between alteration in respiratory nocturnal parameters and EF that has not yet been reported in developmental age. These findings can be considered as the strength and novelty of the present report in a large pediatric population. Keywords: OSAS, polysomnography, executive functions, sleep, sleepiness, children
- Published
- 2013
28. Self-concept evaluation and migraine without aura in childhood
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Esposito M, Gallai B, Parisi L, Castaldo L, Marotta R, Lavano SM, Mazzotta G, Roccella M, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Beatrice Gallai,2 Lucia Parisi,3 Laura Castaldo,1 Rosa Marotta,4 Serena Marianna Lavano,4 Giovanni Mazzotta,5 Michele Roccella,3 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 3Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 4Department of Psychiatry, "Magna Graecia" University of Catanzaro, Catanzaro, Italy; 5Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria 2, Terni, ItalyIntroduction: Self-esteem is related to the broadly understood concept of self-schemas and is a crucial mechanism for a correct psychological development in children and adolescents. The impact of the many psychological difficulties linked to the migraine without aura (MoA) and recurrent headache attacks, such as anger and separation anxiety, on self-esteem has not yet been well investigated. The aims of the present study were to assess self-esteem levels in an objective way and to verify their possible relationship and correlation with the frequency and intensity of migraine attacks, in a population of children and adolescents affected by MoA.Methods: The study population was comprised of 185 children (88 males [M], 97 females [F]) aged between 6 and 12 years (mean 9.04 ± 2.41 years) referred consecutively for MoA to the Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Second University of Naples and of 203 healthy controls (95 M, 108 F) with mean age 9.16 ± 2.37 years, recruited from schools in Campania. The monthly headache frequency and the mean headache duration were assessed from daily headache diaries kept by all the children, and MoA intensity was assessed on a VAS (visual analog scale). To further evaluate their level of self-concept, all subjects filled out the Multidimensional Self-Concept Scale (MSCS).Results: The two study groups were comparable for age (P = 0.621), sex (P = 0.960), and z-score BMI (P = 0.102). The MoA group showed a significant reduction in the MSCS total score (P < 0.001) and in the Social (P < 0.001), Affect (P < 0.001), Family (P < 0.001), and Physical (P < 0.001) domains of the MSCS compared with the control group. The Pearson's correlation analysis showed a significantly negative relationship between MoA clinical characteristics and MSCS scores, and similarly the frequency of attacks was significantly negatively related with the Social (r = −0.3176; P < 0.001), Competence (r = −0.2349; P = 0.001), Physical (r = −0.2378; P = 0.001), and total (r = −0.2825; P < 0.001) scores of the MSCS. On the other hand, the MoA duration was significantly negatively related with the Social (r = −0.1878; P = 0.01), Competence (r = −0.2270; P = 0.002), Physical (r = −0.1976; P = 0.007), and total (r = −0.1903; P = 0.009) scores of the MSCS.Conclusion: Our study first identified differences in self-esteem levels, with an objective tool, in children affected by MoA compared with controls, suggesting the need for evaluation of self-esteem for better psychological pediatric management of children with migraine.Keywords: children, self-esteem, MSCS
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- 2013
29. Temperamental characteristics in childhood migraine without aura: a multicenter study
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Esposito M, Marotta R, Gallai B, Parisi L, Patriciello G, Lavano SM, Mazzotta G, Roccella M, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Rosa Marotta,2 Beatrice Gallai,3 Lucia Parisi,4 Giuseppina Patriciello,1 Serena Marianna Lavano,2 Giovanni Mazzotta,5 Michele Roccella,4 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Department of Psychiatry, "Magna Graecia" University of Catanzaro, Catanzaro, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 4Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 5Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria 2, Terni, ItalyBackground: Children with migraine seem to be more anxious, sensitive, deliberate, cautious, fearful, vulnerable to frustration, tidy, and less physically enduring than comparisons. To the best our knowledge no studies about the temperamental and the characterial dimension aspects in childhood migraine was conducted. Therefore, the aim of the present study was to describe the temperamental and character aspects in a sample of children affected by migraine without aura (MoA) and their relationship with clinical aspects of MoA such as frequency, duration, and severity of attacks.Materials and methods: In our study, 486 children affected by MoA (239 male, 247 female) aged 7–12 years, (mean 10.04 ± 2.53 years) and 518 typical developing children comparable for age (P = 0.227) and sex (P = 0.892) were enrolled to assess their temperamental characteristics. The mothers of all subjects filled out the Junior Temperament and Character Inventory: Parent Version.Results: Children affected by migraine show a higher prevalence of harm avoidance and persistence temperamental domains (P < 0.001) and significantly lower prevalence of the self-directedness character trait (P = 0.023) with respect to the comparisons, according to Cloninger's model. The Spearman rank correlation analysis shows a significant relationship between migraine characteristics and temperamental domains.Conclusion: The present study first identified differences in temperamental characteristics in children affected by MoA with respect to the comparisons, suggesting the need for this evaluation in order for better psychological pediatric management of children with migraine, with possible consequences and impact on the future outcomes of these subjects.Keywords: migraine without aura, children, temperament, JTCI
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- 2013
30. Occlusal traits in developmental dyslexia: a preliminary study
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Perillo L, Esposito M, Contiello M, Lucchese A, Santini AC, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Letizia Perillo,1 Maria Esposito,2 Mariarosaria Contiello,1 Alessandra Lucchese,3 Annamaria Chiara Santini,2 Marco Carotenuto2 1Department of Orthodontics, Second University of Naples, Naples, 2Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, 3Department of Orthodontics, University of Ferrara, Ferrara, Italy Aim: The objective of the study reported here was to assess the orthodontic features in children affected by developmental dyslexia (DD). Patients and methods: A total of 28 children affected by DD (22 boys, six girls; mean age: 9.78 ± 1.69 years) were compared with 51 healthy children (38 boys, 13 girls; mean age 9.41 ± 1.48; range 7–10 years). Reading and writing skills were evaluated along with orthodontic features. Results: The DD and control groups were not significantly different in terms of total intelligence quotient (P = 0.441) and writing skills (P = 0.805 and P = 0.240, respectively), whereas significant differences were observed between the DD group and control group in both word reading (2.018 ± 1.714 vs 0.917 ± 0.563; P = 0.000) and non-word reading (2.537 ± 1.543 vs 0.862 ± 0.244; P = 0.000). Moreover, for many orthodontic features, there was no significant difference between the two groups; only in prevalence of diastemas (57.14%, P = 0.006), midline diastemas (46.42%, P = 0.007), overbite >4 mm (71.42%, P = 0.006) and overjet >4 mm (53.57%, P = 0.001), was there a statistically significant difference. According to univariate logistic regression analysis, the presence of diastemas (odds ratio [OR] 4.33; 95% confidence interval [CI] 1.61–11.65), midline diastemas (OR 4.68; 95% CI 1.61–13.43), an overbite >4 mm (OR 1.75; 95% CI 0.64–4.71), or an overjet >4 mm (OR 2.76; 95% CI 1.06–7.20) seems to play a role in the relationship between occlusal abnormalities and DD in children. Conclusion: Children with DD tend to present with altered dental features, particularly in the area of the incisors, suggesting that a persistently different tongue kinematic profile may thus affect both the developmental variability of the tongue and lip and the occlusion. Keywords: malocclusion, orthodontic features, learning disorder, kinematic profile
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- 2013
31. Visuomotor competencies and primary monosymptomatic nocturnal enuresis in prepubertal aged children
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Esposito M, Gallai B, Parisi L, Roccella M, Marotta R, Lavano SM, Mazzotta G, Patriciello G, Precenzano F, and Carotenuto M
- Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Beatrice Gallai,2 Lucia Parisi,3 Michele Roccella,3 Rosa Marotta,4 Serena Marianna Lavano,4 Giovanni Mazzotta,5 Giuseppina Patriciello,1 Francesco Precenzano,1 Marco Carotenuto1 1Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Italy; 2Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Italy; 3Child Neuropsychiatry, Department of Psychology, University of Palermo, Italy; 4Department of Psychiatry, "Magna Graecia" University of Catanzaro, Catanzaro, Italy; 5Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria 2, Terni, Italy Background: Primary monosymptomatic nocturnal enuresis (PMNE) is a common problem in the developmental ages; it is the involuntary loss of urine during the night in children older than 5 years of age. Several clinical observations have suggested an association between bedwetting and developmental delays in motricity, language development, learning disability, physical growth, and skeletal maturation. The aim of the present study is to evaluate the prevalence of fine motor coordination and visuomotor integration abnormalities in prepubertal children with PMNE. Methods: The study population included 31 children (16 males, 15 females; mean age 8.14 years ± 1.36 years), and the control group comprised 61 typical developing children (32 males, 29 females; mean age 8.03 years ± 1.44 years). The whole population underwent a clinical evaluation to assess total intelligence quotient level, visuomotor integration (VMI) skills, and motor coordination performance (using the Movement Assessment Battery for Children, or M-ABC). Results: No significant differences between the two study groups were found for age (P = 0.725), gender (P = 0.886), z-body mass index (P = 0.149), or intellectual abilities (total intelligence quotient) (P = 0.163). The PMNE group showed a higher prevalence of borderline performance on M-ABC evaluation and in pathologic performance on VMI Total Task compared to controls (P < 0.001). No significant differences between the two study groups were found for pathologic performances on the M-ABC (P = 0.07), VMI Visual Task (P = 0.793), and VMI Motor Task (P = 0.213). Conclusion: Our findings pinpointed that PMNE should not be considered as a voiding disorder alone and, consequently, the children affected should be referred to specific rehabilitative programs that aim to improve motor coordination and visuomotor integration. Keywords: primary monosymptomatic nocturnal enuresis, visuomotor integration, childhood rehabilitation, VMI, M-ABC
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- 2013
32. Maternal stress and childhood migraine: a new perspective on management
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Esposito M, Gallai B, Parisi L, Roccella M, Marotta R, Lavano SM, Gritti A, Mazzotta G, and Carotenuto M
- Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Beatrice Gallai,2 Lucia Parisi,3 Michele Roccella,3 Rosa Marotta,4 Serena Marianna Lavano,4 Antonella Gritti,5 Giovanni Mazzotta,6 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical, and Preventive Medicine, Second University of Naples, Naples, 2Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, 3Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, 4Department of Psychiatry, "Magna Graecia" University of Catanzaro, Catanzaro, 5Suor Orsola Benincasa University, Naples, 6Unit of Child and Adolescent Neuropsychiatry, Azienda Sanitaria Locale 4, Terni, ItalyBackground: Migraine without aura is a primary headache which is frequent and disabling in the developmental age group. No reports are available concerning the prevalence and impact of migraine in children on the degree of stress experienced by parents. The aim of this study was to evaluate the prevalence of maternal stress in a large pediatric sample of individuals affected by migraine without aura.Methods: The study population consisted of 218 children (112 boys, 106 girls) of mean age 8.32 ± 2.06 (range 6–13) years suffering from migraine without aura and a control group of 405 typical developing children (207 boys, 198 girls) of mean age 8.54 ± 2.47 years. Mothers of children in each group answered the Parent Stress Index-Short Form (PSI-SF) questionnaire to assess parental stress levels.Results: The two groups were matched for age (P = 0.262), gender (P = 0.983), and body mass index adjusted for age (P = 0.106). Mothers of children with migraine without aura reported higher mean PSI-SF scores related to the Parental Distress domain (P < 0.001), Dysfunctional Parent-Child Interaction domain (P < 0.001), Difficult Child subscale (P < 0.001), and Total Stress domain than mothers of controls (P < 0.001). No differences between the two groups were found for Defensive Responding subscale scores.Conclusion: Our study may be the first to highlight the presence of high levels of stress in parents of children affected by migraine without aura.Keywords: parental stress, childhood migraine, migraine without aura, children
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- 2013
33. Primary nocturnal enuresis as a risk factor for sleep disorders: an observational questionnaire-based multicenter study
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Esposito M, Gallai B, Parisi L, Roccella M, Marotta R, Lavano SM, Mazzotta G, and Carotenuto M
- Subjects
Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Beatrice Gallai,2 Lucia Parisi,3 Michele Roccella,3 Rosa Marotta,4 Serena Marianna Lavano,4 Giovanni Mazzotta,5 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical and Preventive Medicine, Second University of Naples, Naples, Italy; 2Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, Italy; 3Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 4Department of Psychiatry, “Magna Graecia” University of Catanzaro, Catanzaro, Italy; 5Unit of Child and Adolescent Neuropsychiatry, AUSL Umbria 2, Terni, ItalyIntroduction: Primary nocturnal enuresis (PNE) is a common problem in developmental age with an estimated overall prevalence ranging from 1.6% to 15%, and possible persistence during adolescence. There is a growing interest in the sleep habits of children affected by PNE, which is derived from the contradictory data present in clinical literature. The aim of the present study was to evaluate the presence of sleep disturbances in a population of children affected by PNE, and to identify whether PNE could be considered as a risk factor for sleep disturbances among children.Materials and methods: A total of 190 PNE children (97 males, 93 females) aged 7–15 years, (mean 9.64 ± 1.35 years), and 766 typically developing children matched for age (P = 0.131) and gender (P = 0.963) were enrolled. To evaluate the presence of sleep habits and disturbances, all of the subjects’ mothers filled out the Sleep Disturbances Scale for Children (SDSC), a questionnaire consisting of six subscales: Disorders in Initiating and Maintaining Sleep (DIMS), Sleep Breathing Disorders (SBD), Disorders of Arousal (DA), Sleep–Wake Transition Disorders (SWTD), Disorders of Excessive Somnolence (DOES), and Nocturnal Hyperhidrosis (SHY). The results were divided into “pathological” and “normal” scores using a cut-off value (pathological score = at least three episodes per week), according to the validation criteria of the test. Then, the Chi-square test was used to calculate the statistical difference and a univariate logistic regression analysis was applied to determine the role of PNE as a risk factor for the development of each category of sleep disorders and to calculate the odds ratio (OR).Results: PNE children show a higher prevalence of all sleep disturbances (41.03% DIMS; 85.12% SBD; 63.29% DA; 67.53% SWTD; 31.28% DOES; 37.92% SHY; 25.33% SDSC total score), and according to OR results (SDSC total score OR = 8.293, 95% confidence interval [CI] = 5.079–13.540; DIMS OR = 7.639, 95% CI = 5.192–11.238; SBD OR = 35.633, 95% CI = 22.717–55.893; DA OR = 13.734, 95% CI = 9.476–19.906; SWTD OR = 14.238, 95% CI = 9.829–20.625; DOES OR = 5.602, 95% CI = 3.721–8.432; SHY OR = 6.808, 95% CI = 4.608–10.059), PNE could be considered as a risk factor for the development of sleep disorders.Conclusion: Among PNE children, sleep could be strongly altered, thus helping to affirm the hypothesis that PNE tends to alter sleep architecture, or it could itself be the consequence of an abnormal sleep structure. The findings also point to the existence of a potential increase in the risk of developing sleep disorders in the presence of PNE.Keywords: primary nocturnal enuresis, SDSC, sleep
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- 2013
34. Hypersomnia in children affected by migraine without aura: a questionnaire-based case-control study
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Esposito M, Roccella M, Parisi L, Gallai B, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Michele Roccella,2 Lucia Parisi,2 Beatrice Gallai,3 Marco Carotenuto11Center for Childhood Headache, Unit of Child and Adolescent Neuropsychiatry, Department of Mental Health, Physical, and Preventive Medicine, Second University of Naples, Naples, Italy; 2Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, ItalyBackground: The relationship between sleep and headache is meaningful and complex. Children affected by migraines tend to show many sleep disorders, such as insufficient sleep duration and excessive daytime somnolence. Therefore, the aim of this study is to assess the rate of reported sleep habits and self-reported sleepiness in a large pediatric sample of individuals affected by migraine without aura (MoA).Methods: The study population consisted of 271 children aged between 6 and 13 years affected by MoA. The control group was composed of 305 typically developing children. To assess the sleep habits of all individuals (MoA and control), parents filled out the Sleep Disturbance Scale for Children, and to check the degree of subjective perceived daytime sleepiness, all subjects were administered the Pediatric Daytime Sleepiness Scale.Results: The two study groups were matched for age (P = 0.124), sex distribution (P = 0.775), and body mass index z-score (P = 0.107). Parents of children affected by MoA reported a higher total score of sleep disorder symptoms (P < 0.001), disorders of initiating and maintaining (P < 0.001), and disorders of arousal (P < 0.001) than did parents of controls. No significant differences were found in disorders of excessive somnolence. Conversely, in the Pediatric Daytime Sleepiness Scale, migraine children had higher scores (24.67 ± 3.19 vs 11.94 ± 4.81; P < 0.001) and a reduction in referred total sleep time mean duration (469.83 ± 98.112 vs 527.94 ± 83.02; P < 0.001) than typically developing children.Conclusion: Our study identified differences in sleep habits and found a high prevalence of daytime somnolence in children affected by MoA, suggesting the need for routine sleep screening in the pediatric management of children with migraines.Keywords: excessive daytime sleepiness, drowsiness, sleep disorders, migraine without aura, children
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- 2013
35. Acupressure therapy for insomnia in adolescents: a polysomnographic study
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Carotenuto M, Gallai B, Parisi L, Roccella M, and Esposito M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Marco Carotenuto,1 Beatrice Gallai,2 Lucia Parisi,3 Michele Roccella,3 Maria Esposito11Sleep Clinic for Developmental Age, Clinic of Child and Adolescent Neuropsychiatry, Second University of Naples, Naples, 2Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, 3Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, ItalyBackground: The purpose of this study was to assess the efficacy of acupressure therapy in a sample of adolescents with insomnia using a standard polysomnographic evaluation.Methods: For this study, 25 adolescents affected by psychophysiological insomnia (mean age 15.04 ± 1.18 years, 12 boys) were enrolled. A device known as the Sea-Band® was used by the patients in order to improve their symptoms related to difficulty in falling asleep. All subjects enrolled underwent two sets of consecutive overnight polysomnographic studies in the Sleep Laboratory of the Clinic of Child and Adolescent Neuropsychiatry, comprising two studies at baseline (before treatment) and another two studies at the end of 6 months of treatment.Results: At the end of 6 months of treatment, there was a significant increase in all macrostructural parameters of sleep duration, and a reduction in sleep onset latency, wake after sleep onset, and stage 2 sleep. Moreover, the study group showed a significant increase in percent sleep efficiency (P < 0.001) and in slow wave sleep representation.Conclusion: Acupressure is a noninvasive, safe, and effective method for the management of insomnia in adolescents, with good compliance and no adverse effects.Keywords: insomnia, adolescence, acupressure, polysomnography
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- 2013
36. Can headache impair intellectual abilities in children? An observational study
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Esposito M, Pascotto A, Gallai B, Parisi L, Roccella M, Marotta R, Lavano SM, Gritti A, Mazzotta G, and Carotenuto M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Maria Esposito,1 Antonio Pascotto,1 Beatrice Gallai,3 Lucia Parisi,2 Michele Roccella,2 Rosa Marotta,4 Serena Marianna Lavano,4 Antonella Gritti,5 Giovanni Mazzotta,6 Marco Carotenuto11Center for Childhood Headache, Clinic of Child and Adolescent Neuropsychiatry, Second University of Naples, Naples, 2Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, 4Department of Psychiatry, “Magna Graecia” University of Catanzaro, Catanzaro, 5Suor Orsola Benincasa University, Napoli, 6Unit of Child and Adolescent Neuropsychiatry, Azienda Sanitaria Locale 4, Terni, ItalyBackground: The purpose of this study was to assess the cognitive functioning of children affected by headache, pinpointing the differences in intelligence style between subjects affected by migraine without aura and subjects with tension-type headache.Methods: The study population consisted of 147 children (mean age 10.82 ± 2.17 years) with headache, recruited from the Headache Center for Developmental Age, Child and Adolescent Neuropsychiatry Clinic, Second University of Naples. Cognitive profiling was performed using Weschler Intelligence Scale for Children Third Edition throughout the sample. According to the International Classification of Headache Disorders II criteria for pediatric age, subjects were divided into a migraine without aura group (n = 75; 43 boys, 32 girls) and a tension-type headache group (n = 72; 49 boys, 23 girls). The results were compared with the findings obtained from a sample of 137 healthy control subjects recruited from schools in the Campania region, matched for age and gender.Results: No difference in full intelligence quotient was found between the groups, but the children with tension-type headache had a lower verbal intelligence quotient and a higher performance intelligence quotient than the healthy controls and children with migraine. Factor analysis data showed that the children with migraine seemed to have lower perceptual organization than the children affected by tension-type headache.Conclusion: To our knowledge, studies on cognitive functioning in children affected by headache in the interictal phase are scarce, and our results suggest a new perspective in understanding of the neuropsychological aspects of young patients affected by headaches.Keywords: childhood headache, intelligence quotient, Weschler Intelligence Scale for Children Third Edition, intelligence, migraine
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- 2012
37. Maternal reflexive functions and parent training in children with oppositional defiant disorder
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Frolli A., Saviano E., Carmine D. F., Penna L., Carotenuto M., Ricci M. C., Frolli, A., Saviano, E., Carmine, D. F., Penna, L., Carotenuto, M., and Ricci, M. C.
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Mentalization ,Parent training ,Emotion regulation ,education ,Reflexive functions ,Externalizing problems ,Emotional development ,Oppositional defiant disorder - Abstract
Oppositional Defiant Disorder (ODD) is one of the most common neuropsychiatric disorders in preschool children. Parental self-regulation is critical for maintaining positive parenting practices. However, to the best of our knowledge, existing parental trainings for ODD do not focus on the enhancement of parental reflective functions. In the present study, we compare two models of behavioral Parent Training (PT) for duration of six months: one, already consolidated, is based on the principles of Applied Behavioral Analysis (ABA), the other, innovative, integrates with the model of the regulatory and reflective parental function of Fonagy. Outcomes revealed that the innovative training was more effective as compared to the ABA training shopping that an improvement into the ability of parents to imagine the subjective experience of their developing children increases the development of children's self-regulation.
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- 2021
38. The relationship between maternal reflexive functions and joint attention in neurotypical children
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Alessandro Frolli, Carla, R. M., Antonia, B., Mango, G., Di Carmine, F., Conson, M., Precenzano, F., Carotenuto, M., Frolli, A., Carla, R. M., Antonia, B., Mango, G., Di Carmine, F., Conson, M., Precenzano, F., and Carotenuto, M.
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Theory of mind ,Reflexive function ,Infant ,Mirroring ,Joint attention - Abstract
Joint Attention (JA) can be defined as the coordination of attentional orienting between two persons towards a common object. It develops in typically developing children between 6 and 18 months of age across two phases: Initiating Joint Attention (IJA) and Responding to Joint Attention (RJA). For instance, a parent can initiate JA by pointing to an object and the child can respond by moving her eye gaze towards the parent’s pointing. JA represents one of the first precursors of the Theory of Mind (ToM) implying the person’s ability to think and reason about own and another person's mental states, inferring thoughts, beliefs, intentions and desires. Less is clear, instead, on the relationship between the development of JA abilities in children and the mentalizing abilities of mothers. In the present study, we aimed at investigating the relationships between the infant’s (age range: 15 and 20 months) behaviours relating to IJA and the maternal Reflexive Functions (RF). The results showed a significant correlation between these two skills, thus suggesting that the reflective capacity of mothers can play an important role in development of milestones of the child’s social cognition.
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- 2021
39. Depressive symptoms and childhood sleep apnea syndrome
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Carotenuto M, Esposito M, Parisi L, Gallai B, Marotta R, Pascotto A, and Roccella M
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Neurosciences. Biological psychiatry. Neuropsychiatry ,RC321-571 ,Neurology. Diseases of the nervous system ,RC346-429 - Abstract
Marco Carotenuto,1 Maria Esposito,1 Lucia Parisi,2 Beatrice Gallai,3 Rosa Marotta,4 Antonio Pascotto,1 Michele Roccella21Sleep Clinic for Developmental Age, Clinic of Child and Adolescent Neuropsychiatry, Second University of Naples, Naples, Italy; 2Child Neuropsychiatry, Department of Psychology, University of Palermo, Palermo, Italy; 3Unit of Child and Adolescent Neuropsychiatry, University of Perugia, Perugia, 4Department of Psychiatry, "Magna Graecia" University of Catanzaro, Catanzaro, ItalyBackground: The relationship between sleep and mood regulation is well known, and some reports suggest a key role of sleep-related breathing disorders (SRBD) in the development of the symptomatology of depression, even if no conclusive data are actually found in the clinical literature. The aim of this study was to assess the relationship between SRBD and depressive symptoms in a population of school-aged children.Methods: The study population comprised 94 children affected by SRBD and 107 healthy children. To identify the severity of SRBD, an overnight respiratory evaluation was performed. All subjects filled out the Italian version of the Children Depression Inventory (CDI) to screen for the presence of depressive symptoms.Results: The group with SRBD showed higher CDI scores than the group without SRBD, with a positive correlation found between CDI scores, apnea-hypopnea index, and oxygen desaturation index values. Logistic regression showed that an apnea-hypopnea index ≥ 3 and an oxygen desaturation index ≥ 1 could be risk factors for development of depressive symptoms. According to receiver-operating characteristic curve analysis, the cutoff point for the apnea-hypopnea index that could cause a pathological CDI score (≥19) was >5.66, and the cutoff point for the oxygen desaturation index was >4.2. The limitations of this study are that our data are derived from one single psychometric test and not from a complete psychiatric evaluation, and our subjects came from a small group in southern Italy.Conclusion: Our results suggest the importance of mood assessment in children affected by SRBD.Keywords: depression, sleep-related breathing disorders, cardiorespiratory monitoring, children
- Published
- 2012
40. Migraine and enuresis in children: An unusual correlation?
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Carotenuto, M., Esposito, M., and Pascotto, Antonio
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- 2010
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41. Migraine and obesity: metabolic parameters and response to a weight loss programme
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Verrotti, A., Carotenuto, M., Altieri, L., Parisi, P., Tozzi, E., Belcastro, V., Esposito, M., Guastaferro, N., Ciuti, A., Mohn, A., Chiarelli, F., and Agostinelli, S.
- Published
- 2015
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42. Intellectual disabilities and power spectra analysis during sleep: a new perspective on borderline intellectual functioning
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Esposito, M. and Carotenuto, M.
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- 2014
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43. The insulin gene variable number of tandem repeats (INS VNTR) genotype and sleep disordered breathing in childhood obesity
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Carotenuto, M., Santoro, N., Grandone, A., Santoro, E., Pascotto, C., Pascotto, A., Perrone, L., and del Giudice, E. Miraglia
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- 2009
- Full Text
- View/download PDF
44. Executive functioning in autism spectrum disorders: a case-control study in preschool children
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Carotenuto, M., Ruberto, M., Fontana, M. L., Catania, A., Misuraca, E., Precenzano, F., Lanzara, V., Messina, G., Roccella, M., Daniela SMIRNI, Carotenuto, Marco, Ruberto, Maria, Lorena Fontana, Maria, Catania, Angela, Misuraca, Eliana, Precenzano, Francesco, Lanzara, Valentina, Messina, Giovanni, Roccella, Michele, Smirni, Daniela, and Carotenuto M, Ruberto M, Fontana ML, Catania A, Misuraca E, Precenzano F, Lanzara V, Messina G, Roccella M, Smirni D.
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Autism spectrum disorders, Pre-school children, BRIEF-P, Executive functions ,Settore M-PSI/02 - Psicobiologia E Psicologia Fisiologica ,Settore MED/39 - Neuropsichiatria Infantile - Abstract
Background: Autism spectrum disorders (ASD) are neurobehavioral and developmental conditions that include impairments in a triad of behavioral domains: social development, communication and repetitive behavior/obsessive interests. This case-control study aims to assess executive functioning in ASD preschoolers. Methods: A sample of 50 children participated in the study (24 males and 26 females; age ranged between 2.7 and 3.5 years). The study sample was subdivided into two groups: 25 ASD children and 25 typically developing children as a control group. All participants were administered the BRIEF-P test to assess executive functioning. Results: The two groups were counterbalanced for age and gender. Comparison analysis between the two groups revealed significantly higher scores in ASD children in two subscales of BRIEF-P: inhibition and shifting. Conclusion: These data evidenced significant impairments in several dimensions of executive functions in ASD children. Detecting these deficits at a very early stage of development could therefore have a great impact on clinical practice.
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- 2019
45. Rett syndrome and eye-tracking technology: A brief review
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Diana P., Dansart P., Micale M., Carotenuto M., Salerno M., Tripi G., Diana, P., Dansart, P., Micale, M., Carotenuto, M., Salerno, M., and Tripi, G.
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Eye tracking ,Rett syndrome ,genetic structures ,Cognitive evaluation ,Augmentative communication - Abstract
Introduction: Rett Syndrome is a severe, genetically based neurodevelopment disorder caused mostlyby mutations in the MECP2 gene on the X chromosome. One of the supportive criteria for the diagnosis of this syndrome is intense eye gaze with preferential eye fixation on social stimuli and especially on people’s eyes. This pattern of preferential looking has generally been considered a way to make requests and communicate. Materials and methods: In this review we have collected the studies on the use of eye-tracking technology with subjects with Rett Syndrome. The combination of keywords “Rett Syndrome” and “Eye Tracking” was used in a Medline literature search. In order to be included in this review, studies had to use an eye-tracking instrument and include at least one person with a diagnosis of Rett Syndrome. Results: Among the 16 studies analyzed, 8 studies were performed only on patients with Rett syndrome and 8 studies are case-control studies. 14 studies used a Tobii® device and 2 an unspecified eye gaze device. The objectives of the researches can be divided into 4 large areas: to study the pattern of ocular fixation, the facial recognition skills and the interest in social stimuli of subjects with Rett syndrome; to investigate the real abilities of this patients about cognitive, language, attention and memory; to correlate neurophysiological records with neuropsychological data; to carry out a rehabilitative intervention and to study the results. Conclusion: The eye-tracking technology represents a sensible method for understanding the interior world of individuals with severe apraxia and a limited repertoire of abilities with which to communicate with other people. Providing to girls with Rett Syndrome the ability to respond by looking can increase their communication abilities and may allow us to gain a more realistic understanding of their minds, revealing perceptual and cognitive abilities.
- Published
- 2019
46. Impact of a weight loss program on migraine in obese adolescents
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Verrotti, A., Agostinelli, S., DʼEgidio, C., Di Fonzo, A., Carotenuto, M., Parisi, P., Esposito, M., Tozzi, E., Belcastro, V., Mohn, A., and Battistella, P. A.
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- 2013
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47. Quality of thermoplasticized and single point root fillings assessed by micro-computed tomography
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Somma, F., Cretella, G., Carotenuto, M., Pecci, R., Bedini, R., De Biasi, M., and Angerame, D.
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- 2011
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48. Removal of carbamazepine, diclofenac and trimethoprim by solar driven advanced oxidation processes in a compound triangular collector based reactor: A comparison between homogeneous and heterogeneous processes
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Kowalska, K., primary, Maniakova, G., additional, Carotenuto, M., additional, Sacco, O., additional, Vaiano, V., additional, Lofrano, G., additional, and Rizzo, L., additional
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- 2020
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49. Effects of preterm infant massage on brain development: a spectral EEG study: 2C.2
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DʼACUNTO, G, GUZZETTA, A, BANCALE, A, BERARDI, N, CAROTENUTO, M, GHIRRI, P, and CIONI, G
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- 2010
50. Headache disorders as risk factors for sleep disturbances in school aged children
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Carotenuto, M., Guidetti, V., Ruju, F., Galli, F., Tagliente, F. R., and Pascotto, A.
- Published
- 2005
- Full Text
- View/download PDF
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