1. NIEHS/FDA CLARITY-BPA research program update
- Author
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Sherry M. Lewis, Luísa Camacho, Mani Chidambaram, Gonçalo Gamboa da Costa, Carolyn Favaro, Jodi A. Flaws, Michelle Vanlandingham, Paul C. Howard, Matthew Bryant, Kellie A. Woodling, R. Thomas Zoeller, Retha R. Newbold, K. Barry Delclos, Nigel J. Walker, Michelle McLellen, Nathan C. Twaddle, Thaddeus T. Schug, Jerrold J. Heindel, Jennifer Fostel, John R. Bucher, Sherry A. Ferguson, and Mona I. Churchwell
- Subjects
Male ,Program evaluation ,endocrine system ,Research program ,Biomedical Research ,NTP ,Toxicology ,Risk Assessment ,Article ,law.invention ,Food and drug administration ,Bisphenol A ,Phenols ,law ,Environmental health ,NIEHS ,Animals ,Humans ,Benzhydryl Compounds ,Cooperative Behavior ,Program Development ,Endocrine disruptors ,Safety testing ,Dose-Response Relationship, Drug ,urogenital system ,business.industry ,CLARITY-BPA ,Environmental Exposure ,Environmental exposure ,Public relations ,Chemical used ,3. Good health ,Interinstitutional Relations ,Human exposure ,Models, Animal ,CLARITY ,Environmental Pollutants ,Female ,business ,FDA ,Consortium ,hormones, hormone substitutes, and hormone antagonists ,Program Evaluation - Abstract
Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA previously evaluated the body of BPA toxicology data and determined that BPA is safe at current exposure levels. Although consistent with the assessment of some other regulatory agencies around the world, this determination of BPA safety continues to be debated in scientific and popular publications, resulting in conflicting messages to the public. Thus, the National Toxicology Program (NTP), National Institute of Environmental Health Sciences (NIEHS), and U.S. Food and Drug Administration (FDA) developed a consortium-based research program to link more effectively a variety of hypothesis-based research investigations and guideline-compliant safety testing with BPA. This collaboration is known as the Consortium Linking Academic and Regulatory Insights on BPA Toxicity (CLARITY-BPA). This paper provides a detailed description of the conduct of the study and a midterm update on progress of the CLARITY-BPA research program.
- Published
- 2015
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