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Introduction: In Cavernous transformation of portal vein (CTPV), therapeutic options are limited; however the restoration of circulation by mesenteric-portal bypass (MPB) is an option in selected cases. CASE REPORT 1: 13-year-old female with polymalformative syndrome. Admission at 4 months of age to Intensive Care Unit due to severe pneumonia with hemodynamic instability. Follow up due to thrombocytopenia and splenomegalia she was diagnosed CTPV at7-years old. At 13y-old she was submitted to MPB. CASE REPORT 2: 9-years-old male; severe neonatal Rh isoimmunization treated with exsanguinations. Followed-up since 6-months ofage due to thrombocytopenia and splenomegalia, and at 3 years of age he was diagnosed CTPV. Due to disease progression he was proposed as candidate to MBP which was contraindicated due to vascular thrombosis of the Rex recess., Comments: MBP presents as one of the few therapeutic options to CTPV in children; due to its specificity and rigid requirements it is vital the close follow up and early diagnosis.

Cough is perhaps the most frequently seen symptom in children and as such one of the most common reasons for physician appointments. The mechanics and causes of cough in children are different to those in adults and imply a different diagnostic and therapeutic management. This article reviews the physiopathology of cough in children, the most frequent causes, the initial evaluation and the treatment slant.