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11 results on '"Carneiro, Gabriel Reis Alves"'

3. Asperelines Produced by the Endophytic Fungus Trichoderma asperelloides From the Aquatic Plant Victoria amazonica

Author

Fernandes, Kamila Rangel Primo, de Souza, Antonia Queiroz Lima, dos Santos, Lane Alencar, Nogueira, Fábio César Sousa, Evaristo, Joseph Albert Medeiros, Carneiro, Gabriel Reis Alves, da Silva, Gilvan Ferreira, da Cruz, Jeferson Chagas, Sousa, Thiago Fernandes, da Silva, Sarah Raquel Silveira, dos Santos Bastos, Ivanildes, Orlandi, Patrícia Puccinelli, and de Souza, Afonso Duarte Leão

Published
2021
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7. Proteogenomics Reveals how Metastatic Melanoma Modulates the Immune System to Allow Immune Evasion

Author

Gil, Jeovanis, primary, Kim, Yonghyo, additional, Szeitz, Beáta, additional, Doma, Viktória, additional, Çakır, Uğur, additional, de Almeida, Natália Pinto, additional, Hagemeijer, Yanick Paco, additional, Guryev, Victor, additional, Johansson, Jenny G, additional, Sharma, Yogita, additional, Parada, Indira Pla, additional, Horvath, Zsolt, additional, de Siqueira Guedes, Jéssica, additional, Monnerat, Gustavo, additional, Carneiro, Gabriel Reis Alves, additional, CS Nogueira, Fábio, additional, Lee, Boram, additional, Oskolas, Henriett, additional, Kuroli, Enikő, additional, Hársing, Judit, additional, Sugihara, Yutaka, additional, Kuras, Magdalena, additional, Appelqvist, Roger, additional, Wieslander, Elisabet, additional, Domont, Gilberto B, additional, Baldetorp, Bo, additional, Hong, Runyu, additional, Huszty, Gergely, additional, Vizkeleti, Laura, additional, Tímár, József, additional, Fenyö, David, additional, Betancourt, Lazaro Hiram, additional, Jakobsson, Johan, additional, Malm, Johan, additional, Sanchez, Aniel, additional, Szász, A. Marcell, additional, Horvatovich, Peter, additional, Rezeli, Melinda, additional, Kárpáti, Sarolta, additional, and Marko-Varga, György, additional

Published
2021
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9. Asperelines Produced by the Endophytic Fungus Trichoderma asperelloidesFrom the Aquatic Plant Victoria amazonica

Author

Fernandes, Kamila Rangel Primo, de Souza, Antonia Queiroz Lima, dos Santos, Lane Alencar, Nogueira, Fábio César Sousa, Evaristo, Joseph Albert Medeiros, Carneiro, Gabriel Reis Alves, da Silva, Gilvan Ferreira, da Cruz, Jeferson Chagas, Sousa, Thiago Fernandes, da Silva, Sarah Raquel Silveira, dos Santos Bastos, Ivanildes, Orlandi, Patrícia Puccinelli, and de Souza, Afonso Duarte Leão

Abstract

Graphical abstract:

Published
2021
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10. Zebrafish (Danio rerio) water tank model for the investigation of drug metabolism: Progress, outlook, and challenges

Author

Sardela, Vinicius Figueiredo, primary, Anselmo, Carina de Souza, additional, Nunes, Isabelle Karine da Costa, additional, Carneiro, Gabriel Reis Alves, additional, Santos, Gustavo Ramalho Cardoso, additional, Carvalho, Aline Reis, additional, Labanca, Bruna de Jesus, additional, Silva Oliveira, Daniely, additional, Ribeiro, William Dias, additional, Araujo, Amanda Lessa Dutra, additional, Padilha, Monica Costa, additional, Lima, Cleverton Kleiton Freitas, additional, Sousa, Valeria Pereira, additional, Aquino Neto, Francisco Radler, additional, and Gualberto Pereira, Henrique Marcelo, additional

Published
2018
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11. Amniotic fluid metabolomics identifies impairment of glycerophospholipid and amino acid metabolism during congenital Zika syndrome development.

Author

Sosa-Acosta P, Evaristo GPC, Evaristo JAM, Carneiro GRA, Quiñones-Vega M, Monnerat G, Melo A, Garcez PP, Nogueira FCS, and Domont GB

Subjects
Female, Pregnancy, Humans, Amniotic Fluid, Placenta, Amino Acids, Lipids, Zika Virus Infection complications, Zika Virus, Pregnancy Complications, Infectious, Microcephaly
Abstract

Purpose: Our main goal is to identify the alterations in the amniotic fluid (AF) metabolome in Zika virus (ZIKV)-infected patients and their relation to congenital Zika syndrome (CZS) progression., Experimental Design: We applied an untargeted metabolomics strategy to analyze seven AF of pregnant women: healthy women and ZIKV-infected women bearing non-microcephalic and microcephalic fetuses., Results: Infected patients were characterized by glycerophospholipid metabolism impairment, which is accentuated in microcephalic phenotypes. Glycerophospholipid decreased concentration in AF can be a consequence of intracellular transport of lipids to the placental or fetal tissues under development. The increased intracellular concentration of lipids can lead to mitochondrial dysfunction and neurodegeneration caused by lipid droplet accumulation. Furthermore, the dysregulation of amino acid metabolism was a molecular fingerprint of microcephalic phenotypes, specifically serine, and proline metabolisms. Both amino acid deficiencies were related to neurodegenerative disorders, intrauterine growth retardation, and placental abnormalities., Conclusions and Clinical Relevance: This study enhances our understanding of the development of CZS pathology and sheds light on dysregulated pathways that could be relevant for future studies., (© 2023 Wiley-VCH GmbH.)

Published
2024
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