Search

Your search keyword '"Carlson, Erin E."' showing total 467 results
Start Over Author "Carlson, Erin E."
467 results on '"Carlson, Erin E."'

1. Evaluation of expanded 2-aminobenzothiazole library as inhibitors of a model histidine kinase and virulence suppressors in Pseudomonas aeruginosa

Author

Fihn, Conrad A., Lembke, Hannah K., Gaulin, Jeffrey, Bouchard, Patricia, Villarreal, Alex R., Penningroth, Mitchell R., Crone, Kathryn K., Vogt, Grace A., Gilbertsen, Adam J., Ayotte, Yann, Coutinho de Oliveira, Luciana, Serrano-Wu, Michael H., Drouin, Nathalie, Hung, Deborah T., Hunter, Ryan C., and Carlson, Erin E.

Published
2024
Full Text
View/download PDF

10. Data from Breast Cancer Polygenic-Risk Score Influence on Risk-Reducing Endocrine Therapy Use: Genetic Risk Estimate (GENRE) Trial 1-Year and 2-Year Follow-Up

Author

Stan, Daniela L., primary, Kim, Julian O., primary, Schaid, Daniel J., primary, Carlson, Erin E., primary, Kim, Christina A., primary, Sinnwell, Jason P., primary, Couch, Fergus J., primary, Vachon, Celine M., primary, Cooke, Andrew L., primary, Goldenberg, Benjamin A., primary, and Pruthi, Sandhya, primary

Published
2024
Full Text
View/download PDF

11. Supplemental Figure 1 from Breast Cancer Polygenic-Risk Score Influence on Risk-Reducing Endocrine Therapy Use: Genetic Risk Estimate (GENRE) Trial 1-Year and 2-Year Follow-Up

Author

Stan, Daniela L., primary, Kim, Julian O., primary, Schaid, Daniel J., primary, Carlson, Erin E., primary, Kim, Christina A., primary, Sinnwell, Jason P., primary, Couch, Fergus J., primary, Vachon, Celine M., primary, Cooke, Andrew L., primary, Goldenberg, Benjamin A., primary, and Pruthi, Sandhya, primary

Published
2024
Full Text
View/download PDF

12. Supplemental Materials and Methods 1 from Breast Cancer Polygenic-Risk Score Influence on Risk-Reducing Endocrine Therapy Use: Genetic Risk Estimate (GENRE) Trial 1-Year and 2-Year Follow-Up

Author

Stan, Daniela L., primary, Kim, Julian O., primary, Schaid, Daniel J., primary, Carlson, Erin E., primary, Kim, Christina A., primary, Sinnwell, Jason P., primary, Couch, Fergus J., primary, Vachon, Celine M., primary, Cooke, Andrew L., primary, Goldenberg, Benjamin A., primary, and Pruthi, Sandhya, primary

Published
2024
Full Text
View/download PDF

13. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

Author

Wang, Mingxun, Carver, Jeremy J, Phelan, Vanessa V, Sanchez, Laura M, Garg, Neha, Peng, Yao, Nguyen, Don Duy, Watrous, Jeramie, Kapono, Clifford A, Luzzatto-Knaan, Tal, Porto, Carla, Bouslimani, Amina, Melnik, Alexey V, Meehan, Michael J, Liu, Wei-Ting, Crüsemann, Max, Boudreau, Paul D, Esquenazi, Eduardo, Sandoval-Calderón, Mario, Kersten, Roland D, Pace, Laura A, Quinn, Robert A, Duncan, Katherine R, Hsu, Cheng-Chih, Floros, Dimitrios J, Gavilan, Ronnie G, Kleigrewe, Karin, Northen, Trent, Dutton, Rachel J, Parrot, Delphine, Carlson, Erin E, Aigle, Bertrand, Michelsen, Charlotte F, Jelsbak, Lars, Sohlenkamp, Christian, Pevzner, Pavel, Edlund, Anna, McLean, Jeffrey, Piel, Jörn, Murphy, Brian T, Gerwick, Lena, Liaw, Chih-Chuang, Yang, Yu-Liang, Humpf, Hans-Ulrich, Maansson, Maria, Keyzers, Robert A, Sims, Amy C, Johnson, Andrew R, Sidebottom, Ashley M, Sedio, Brian E, Klitgaard, Andreas, Larson, Charles B, Boya P, Cristopher A, Torres-Mendoza, Daniel, Gonzalez, David J, Silva, Denise B, Marques, Lucas M, Demarque, Daniel P, Pociute, Egle, O'Neill, Ellis C, Briand, Enora, Helfrich, Eric JN, Granatosky, Eve A, Glukhov, Evgenia, Ryffel, Florian, Houson, Hailey, Mohimani, Hosein, Kharbush, Jenan J, Zeng, Yi, Vorholt, Julia A, Kurita, Kenji L, Charusanti, Pep, McPhail, Kerry L, Nielsen, Kristian Fog, Vuong, Lisa, Elfeki, Maryam, Traxler, Matthew F, Engene, Niclas, Koyama, Nobuhiro, Vining, Oliver B, Baric, Ralph, Silva, Ricardo R, Mascuch, Samantha J, Tomasi, Sophie, Jenkins, Stefan, Macherla, Venkat, Hoffman, Thomas, Agarwal, Vinayak, Williams, Philip G, Dai, Jingqui, Neupane, Ram, Gurr, Joshua, Rodríguez, Andrés MC, Lamsa, Anne, Zhang, Chen, Dorrestein, Kathleen, Duggan, Brendan M, Almaliti, Jehad, Allard, Pierre-Marie, and Phapale, Prasad

Subjects
Analytical Chemistry, Chemical Sciences, Generic health relevance, Biological Products, Data Curation, Database Management Systems, Databases, Chemical, Information Dissemination, Information Storage and Retrieval, Internationality, Mass Spectrometry
Abstract

The potential of the diverse chemistries present in natural products (NP) for biotechnology and medicine remains untapped because NP databases are not searchable with raw data and the NP community has no way to share data other than in published papers. Although mass spectrometry (MS) techniques are well-suited to high-throughput characterization of NP, there is a pressing need for an infrastructure to enable sharing and curation of data. We present Global Natural Products Social Molecular Networking (GNPS; http://gnps.ucsd.edu), an open-access knowledge base for community-wide organization and sharing of raw, processed or identified tandem mass (MS/MS) spectrometry data. In GNPS, crowdsourced curation of freely available community-wide reference MS libraries will underpin improved annotations. Data-driven social-networking should facilitate identification of spectra and foster collaborations. We also introduce the concept of 'living data' through continuous reanalysis of deposited data.

Published
2016

14. Activity-Based Protein Profiling Methods to Study Bacteria: The Power of Small-Molecule Electrophiles

Author

Sharifzadeh, Shabnam, Shirley, Joshua D., Carlson, Erin E., Compans, Richard W, Series Editor, Malissen, Bernard, Series Editor, Aktories, Klaus, Series Editor, Rappuoli, Rino, Series Editor, Galan, Jorge E, Series Editor, Ahmed, Rafi, Series Editor, Palme, Klaus, Series Editor, Casadevall, Arturo, Series Editor, Garcia-Sastre, Adolfo, Series Editor, Iwasaki, Akiko, Series Editor, Akira, Shizuo, Series Editor, Cravatt, Benjamin F., editor, Hsu, Ku-Lung, editor, and Weerapana, Eranthie, editor

Published
2019
Full Text
View/download PDF

15. Real-Time Visualization of 'in Vitro' Transcription of a Fluorescent RNA Aptamer: An Experiment for the Upper-Division Undergraduate or First Year Graduate Laboratory

Author

Heili, Joseph M., Gomez-Garcia, Jose, Gaut, Nathaniel J., Cash, Brock W., Aufdembrink, Lauren M., Heffron, Brent A., Shirley, Joshua D., Carlson, Erin E., Adamala, Katarzyna P., and Englehart, Aaron E.

Abstract

A teaching laboratory experiment is described where students prepare in vitro transcription reactions of a fluorescent RNA aptamer, named Broccoli, and observe the production of the aptamer in real-time on a fluorescence plate reader. Alternate visualization methods with minimal costs are also described for laboratories lacking this instrumentation. Two optional experiments are also described. Optional Experiment 1 involves purification of RNA transcription reactions using a commercial spin column kit and having students correlate cleanup kit yield with transcribed aptamer fluorescence. Optional Experiment 2 involves running a polyacrylamide gel of the transcription reaction with a ladder, followed by staining with (Z)-4-(3',5'-difluoro-4'- hydroxybenzylidene)-2-methyl-1-(2?,2?,2?-trifluoroethyl)-1H-imidazol-5-(4H)-one (DFHBI-1T) (selective for Broccoli) and a second stain with SYBR Gold (nonselective, allowing for simultaneous visualization of Broccoli and ladder). This experiment has the practical advantage of enabling aptamer visualization in laboratories without a fluorescence spectrometer or plate reader, as well as the pedagogical benefit of demonstrating specific activation of the fluorescence of a small molecule by an RNA aptamer in another context (gel staining). Each experiment allows students to perform straightforward, easily understood teaching laboratory experiments, including key concepts in cellular imaging, and RNA biochemistry widely employed in biochemical research.

Published
2018
Full Text
View/download PDF

16. Breast Cancer Polygenic-Risk Score Influence on Risk-Reducing Endocrine Therapy Use: Genetic Risk Estimate (GENRE) Trial 1-Year and 2-Year Follow-Up

Author

Stan, Daniela L., primary, Kim, Julian O., additional, Schaid, Daniel J., additional, Carlson, Erin E., additional, Kim, Christina A., additional, Sinnwell, Jason P., additional, Couch, Fergus J., additional, Vachon, Celine M., additional, Cooke, Andrew L., additional, Goldenberg, Benjamin A., additional, and Pruthi, Sandhya, additional

Published
2023
Full Text
View/download PDF

24. Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition of Pseudomonas aeruginosa Virulence Phenotypes

Author

Fihn, Conrad, primary, Lembke, Hannah, additional, Gaulin, Jeffrey, additional, Bouchard, Patricia, additional, Penningroth, Mitchell R, additional, Crone, Kathryn, additional, Vogt, Grace, additional, Gilbertsen, Adam, additional, Ayotte, Yann, additional, CouthinodeOliveira, Luciana, additional, Serrano-Wu, Michael, additional, Drouin, Nathalie, additional, Hung, Deborah, additional, Hunter, Ryan C, additional, and Carlson, Erin E, additional

Published
2023
Full Text
View/download PDF

25. Evaluation of Expanded 2-Aminobenzothiazole Library for Inhibition ofPseudomonas aeruginosaVirulence Phenotypes

Author

Fihn, Conrad A., Lembke, Hannah K., Gaulin, Jeffrey, Bouchard, Patricia, Penningroth, Mitchell R., Crone, Kathryn K., Vogt, Grace A., Gilbertsen, Adam J., Ayotte, Yann, de Oliveira, Luciana Couthino, Serrano-Wu, Michael H., Drouin, Nathalie, Hung, Deborah T., Hunter, Ryan C., and Carlson, Erin E.

Subjects
Article
Abstract

Bacterial resistance to antibiotics is a rapidly increasing threat to human health. New strategies to combat resistant organisms are desperately needed. One potential avenue is targeting two-component systems, which are the main bacterial signal transduction pathways used to regulate development, metabolism, virulence, and antibiotic resistance. These systems consist of a homodimeric membrane-bound sensor histidine kinase, and a cognate effector, the response regulator. The high sequence conservation in the catalytic and adenosine triphosphate-binding (CA) domain of histidine kinases and their essential role in bacterial signal transduction could enable broad-spectrum antibacterial activity. Through this signal transduction, histidine kinases regulate multiple virulence mechanisms including toxin production, immune evasion, and antibiotic resistance. Targeting virulence, as opposed to development of bactericidal compounds, could reduce evolutionary pressure for acquired resistance. Additionally, compounds targeting the CA domain have the potential to impair multiple two-component systems that regulate virulence in one or more pathogens. We conducted structure-activity relationship studies of 2-aminobenzothiazole-based inhibitors designed to target the CA domain of histidine kinases. We found these compounds have anti-virulence activities inPseudomonas aeruginosa,reducing motility phenotypes and toxin production associated with the pathogenic functions of this bacterium.Abstract Figure

Published
2023
Full Text
View/download PDF

26. Deep sequencing across germline genome-wide association study signals relating to breast cancer events in women receiving aromatase inhibitors for adjuvant therapy of early breast cancer

Author

Ingle, James N., Kalari, Krishna R., Momozawa, Yukihide, Kubo, Michiaki, Furukawa, Yoichi, Shepherd, Lois E., Ellis, Matthew J., Goss, Paul E., Barman, Poulami, Carlson, Erin E., Sinnwell, Jason P., Tang, Xiaojia, Goetz, Matthew P., Chen, Bingshu E., Cairns, Junmei, Weinshilboum, Richard M., and Wang, Liewei

Published
2019
Full Text
View/download PDF

27. Supplementary Figure S2 from Selective Estrogen Receptor Modulators and Pharmacogenomic Variation in ZNF423 Regulation of BRCA1 Expression: Individualized Breast Cancer Prevention

Author

Ingle, James N., primary, Liu, Mohan, primary, Wickerham, D. Lawrence, primary, Schaid, Daniel J., primary, Wang, Liewei, primary, Mushiroda, Taisei, primary, Kubo, Michiaki, primary, Costantino, Joseph P., primary, Vogel, Victor G., primary, Paik, Soonmyung, primary, Goetz, Matthew P., primary, Ames, Matthew M., primary, Jenkins, Gregory D., primary, Batzler, Anthony, primary, Carlson, Erin E., primary, Flockhart, David A., primary, Wolmark, Norman, primary, Nakamura, Yusuke, primary, and Weinshilboum, Richard M., primary

Published
2023
Full Text
View/download PDF

28. Data from Selective Estrogen Receptor Modulators and Pharmacogenomic Variation in ZNF423 Regulation of BRCA1 Expression: Individualized Breast Cancer Prevention

Author

Ingle, James N., primary, Liu, Mohan, primary, Wickerham, D. Lawrence, primary, Schaid, Daniel J., primary, Wang, Liewei, primary, Mushiroda, Taisei, primary, Kubo, Michiaki, primary, Costantino, Joseph P., primary, Vogel, Victor G., primary, Paik, Soonmyung, primary, Goetz, Matthew P., primary, Ames, Matthew M., primary, Jenkins, Gregory D., primary, Batzler, Anthony, primary, Carlson, Erin E., primary, Flockhart, David A., primary, Wolmark, Norman, primary, Nakamura, Yusuke, primary, and Weinshilboum, Richard M., primary

Published
2023
Full Text
View/download PDF

29. Supplementary Material from Selective Estrogen Receptor Modulators and Pharmacogenomic Variation in ZNF423 Regulation of BRCA1 Expression: Individualized Breast Cancer Prevention

Author

Ingle, James N., primary, Liu, Mohan, primary, Wickerham, D. Lawrence, primary, Schaid, Daniel J., primary, Wang, Liewei, primary, Mushiroda, Taisei, primary, Kubo, Michiaki, primary, Costantino, Joseph P., primary, Vogel, Victor G., primary, Paik, Soonmyung, primary, Goetz, Matthew P., primary, Ames, Matthew M., primary, Jenkins, Gregory D., primary, Batzler, Anthony, primary, Carlson, Erin E., primary, Flockhart, David A., primary, Wolmark, Norman, primary, Nakamura, Yusuke, primary, and Weinshilboum, Richard M., primary

Published
2023
Full Text
View/download PDF

30. Supplementary Figure S2 from Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy

Author

Ingle, James N., primary, Xie, Fang, primary, Ellis, Matthew J., primary, Goss, Paul E., primary, Shepherd, Lois E., primary, Chapman, Judith-Anne W., primary, Chen, Bingshu E., primary, Kubo, Michiaki, primary, Furukawa, Yoichi, primary, Momozawa, Yukihide, primary, Stearns, Vered, primary, Pritchard, Kathleen I., primary, Barman, Poulami, primary, Carlson, Erin E., primary, Goetz, Matthew P., primary, Weinshilboum, Richard M., primary, Kalari, Krishna R., primary, and Wang, Liewei, primary

Published
2023
Full Text
View/download PDF

31. Supplementary Figure from Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer

Author

Fasching, Peter A., primary, Liu, Duan, primary, Scully, Steve, primary, Ingle, James N., primary, Lyra, Paulo C., primary, Rack, Brigitte, primary, Hein, Alexander, primary, Ekici, Arif B., primary, Reis, Andre, primary, Schneeweiss, Andreas, primary, Tesch, Hans, primary, Fehm, Tanja N., primary, Heinrich, Georg, primary, Beckmann, Matthias W., primary, Ruebner, Matthias, primary, Huebner, Hanna, primary, Lambrechts, Diether, primary, Madden, Ebony, primary, Shen, Jess, primary, Romm, Jane, primary, Doheny, Kim, primary, Jenkins, Gregory D., primary, Carlson, Erin E., primary, Li, Liang, primary, Fridley, Brooke L., primary, Cunningham, Julie M., primary, Janni, Wolfgang, primary, Monteiro, Alvaro N.A., primary, Schaid, Daniel J., primary, Häberle, Lothar, primary, Weinshilboum, Richard M., primary, and Wang, Liewei, primary

Published
2023
Full Text
View/download PDF

32. Data from Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer

Author

Fasching, Peter A., primary, Liu, Duan, primary, Scully, Steve, primary, Ingle, James N., primary, Lyra, Paulo C., primary, Rack, Brigitte, primary, Hein, Alexander, primary, Ekici, Arif B., primary, Reis, Andre, primary, Schneeweiss, Andreas, primary, Tesch, Hans, primary, Fehm, Tanja N., primary, Heinrich, Georg, primary, Beckmann, Matthias W., primary, Ruebner, Matthias, primary, Huebner, Hanna, primary, Lambrechts, Diether, primary, Madden, Ebony, primary, Shen, Jess, primary, Romm, Jane, primary, Doheny, Kim, primary, Jenkins, Gregory D., primary, Carlson, Erin E., primary, Li, Liang, primary, Fridley, Brooke L., primary, Cunningham, Julie M., primary, Janni, Wolfgang, primary, Monteiro, Alvaro N.A., primary, Schaid, Daniel J., primary, Häberle, Lothar, primary, Weinshilboum, Richard M., primary, and Wang, Liewei, primary

Published
2023
Full Text
View/download PDF

33. Supplementary Data from Identification of Two Genetic Loci Associated with Leukopenia after Chemotherapy in Patients with Breast Cancer

Author

Fasching, Peter A., primary, Liu, Duan, primary, Scully, Steve, primary, Ingle, James N., primary, Lyra, Paulo C., primary, Rack, Brigitte, primary, Hein, Alexander, primary, Ekici, Arif B., primary, Reis, Andre, primary, Schneeweiss, Andreas, primary, Tesch, Hans, primary, Fehm, Tanja N., primary, Heinrich, Georg, primary, Beckmann, Matthias W., primary, Ruebner, Matthias, primary, Huebner, Hanna, primary, Lambrechts, Diether, primary, Madden, Ebony, primary, Shen, Jess, primary, Romm, Jane, primary, Doheny, Kim, primary, Jenkins, Gregory D., primary, Carlson, Erin E., primary, Li, Liang, primary, Fridley, Brooke L., primary, Cunningham, Julie M., primary, Janni, Wolfgang, primary, Monteiro, Alvaro N.A., primary, Schaid, Daniel J., primary, Häberle, Lothar, primary, Weinshilboum, Richard M., primary, and Wang, Liewei, primary

Published
2023
Full Text
View/download PDF

34. Data from Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy

Author

Ingle, James N., primary, Xie, Fang, primary, Ellis, Matthew J., primary, Goss, Paul E., primary, Shepherd, Lois E., primary, Chapman, Judith-Anne W., primary, Chen, Bingshu E., primary, Kubo, Michiaki, primary, Furukawa, Yoichi, primary, Momozawa, Yukihide, primary, Stearns, Vered, primary, Pritchard, Kathleen I., primary, Barman, Poulami, primary, Carlson, Erin E., primary, Goetz, Matthew P., primary, Weinshilboum, Richard M., primary, Kalari, Krishna R., primary, and Wang, Liewei, primary

Published
2023
Full Text
View/download PDF

35. Supplementary Material from Genetic Polymorphisms in the Long Noncoding RNA MIR2052HG Offer a Pharmacogenomic Basis for the Response of Breast Cancer Patients to Aromatase Inhibitor Therapy

Author

Ingle, James N., primary, Xie, Fang, primary, Ellis, Matthew J., primary, Goss, Paul E., primary, Shepherd, Lois E., primary, Chapman, Judith-Anne W., primary, Chen, Bingshu E., primary, Kubo, Michiaki, primary, Furukawa, Yoichi, primary, Momozawa, Yukihide, primary, Stearns, Vered, primary, Pritchard, Kathleen I., primary, Barman, Poulami, primary, Carlson, Erin E., primary, Goetz, Matthew P., primary, Weinshilboum, Richard M., primary, Kalari, Krishna R., primary, and Wang, Liewei, primary

Published
2023
Full Text
View/download PDF

36. Supplementary Data Clean from Anastrozole has an Association between Degree of Estrogen Suppression and Outcomes in Early Breast Cancer and is a Ligand for Estrogen Receptor α

Author

Ingle, James N., primary, Cairns, Junmei, primary, Suman, Vera J., primary, Shepherd, Lois E., primary, Fasching, Peter A., primary, Hoskin, Tanya L., primary, Singh, Ravinder J., primary, Desta, Zeruesenay, primary, Kalari, Krishna R., primary, Ellis, Matthew J., primary, Goss, Paul E., primary, Chen, Bingshu E., primary, Volz, Bernhard, primary, Barman, Poulami, primary, Carlson, Erin E., primary, Haddad, Tufia, primary, Goetz, Matthew P., primary, Goodnature, Barbara, primary, Cuellar, Matthew E., primary, Walters, Michael A., primary, Correia, Cristina, primary, Kaufmann, Scott H., primary, Weinshilboum, Richard M., primary, and Wang, Liewei, primary

Published
2023
Full Text
View/download PDF

42. SLCO1B1 polymorphisms and plasma estrone conjugates in postmenopausal women with ER+ breast cancer: genome-wide association studies of the estrone pathway

Author

Dudenkov, Tanda M., Ingle, James N., Buzdar, Aman U., Robson, Mark E., Kubo, Michiaki, Ibrahim-zada, Irada, Batzler, Anthony, Jenkins, Gregory D., Pietrzak, Tracy L., Carlson, Erin E., Barman, Poulami, Goetz, Matthew P., Northfelt, Donald W., Moreno-Aspita, Alvaro, Williard, Clark V., Kalari, Krishna R., Nakamura, Yusuke, Wang, Liewei, and Weinshilboum, Richard M.

Published
2017
Full Text
View/download PDF

49. Plant Pigment Identification: A Classroom and Outreach Activity

Author

Garber, Kathleen C. A., Odendaal, Antoinette Y., and Carlson, Erin E.

Abstract

Anthocyanins are a class of pigments responsible for the bright colors of many flowers, fruits, and vegetables typically resulting in shades of red, blue, and purple. Students were asked to perform an activity to enable them to identify which anthocyanin was present in one of several possible plant materials through a hands-on activity. Students extracted the pigments from the biological sources and obtained color profiles by altering the pH of the biological extracts. These extracts were compared to standards of anthocyanin pigments so that students could deduce which pigment was present in the plant material that they had selected. This activity interrelates several chemical concepts and provides a link between chemical and biological sciences.

Published
2013
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results