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Your search keyword '"Carlos Toshinori Maeda"' showing total 7 results
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7 results on '"Carlos Toshinori Maeda"'

1. Analysis of tissue inflammatory response, fibroplasia, and foreign body reaction between the polyglactin suture of abdominal aponeurosis in rats and the intraperitoneal implant of polypropylene, polypropylene/polyglecaprone and polyester/porcine collagen meshes

Author

Waston Gonçalves Ribeiro, Adriana Carneiro Corrêa Nascimento, Larissa Brito Ferreira, Danilo Dallago De Marchi, Gustavo Moraes Rego, Carlos Toshinori Maeda, Gyl Eanes Barros Silva, Ricardo Artigiani Neto, Orlando Jorge Martins Torres, and Marcos Bettini Pitombo

Subjects
Surgical Mesh, Inflammation, Collagen, Foreign Body Reaction, Rats, Surgery, RD1-811
Abstract

ABSTRACT Purpose To compare tissue inflammatory response, foreign body reaction, fibroplasia, and proportion of type I/III collagen between closure of abdominal wall aponeurosis using polyglactin suture and intraperitoneal implant of polypropylene, polypropylene/polyglecaprone, and polyester/porcine collagen meshes to repair defects in the abdominal wall of rats. Methods Forty Wistar rats were placed in four groups, ten animals each, for the intraperitoneal implant of polypropylene, polypropylene/polyglecaprone, and polyester/porcine collagen meshes or suture with polyglactin (sham) after creation of defect in the abdominal wall. Twenty-one days later, histological analysis was performed after staining with hematoxylin-eosin and picrosirius red. Results The groups with meshes had a higher inflammation score (p < 0.05) and higher number of gigantocytes (p < 0.05) than the sham group, which had a better fibroplasia with a higher proportion of type I/III collagen than the tissue separating meshes (p < 0.05). There were no statistically significant differences between the three groups with meshes. Conclusions The intraperitoneal implant of polypropylene/polyglecaprone and polyester/porcine collagen meshes determined a more intense tissue inflammatory response with exuberant foreign body reaction, immature fibroplasia and low tissue proportion of type I/III collagen compared to suture with polyglactin of abdominal aponeurosis. However, there were no significant differences in relation to the polypropylene mesh group.

Published
2021
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2. Does mesenchymal stem cell improve the liver regeneration after the 70% hepatectomy?

Author

Ana Karina Soares Alves, Valéria Lanzoni, Rogério Aoki Fuziy, Rita Maria Aparecida Monteiro Moura Franco, Carlos Toshinori Maeda, Gaspar de Jesus Lopes Filho, and Marcelo Moura Linhares

Subjects
Mesenchymal Stem Cell Transplantation, Liver Regeneration, Hepatectomy, Cell- and Tissue-Based Therapy, Rats, Surgery, RD1-811
Abstract

Abstract Purpose: To evaluate the effects of mesenchymal stem cells on liver regeneration in rats following a 70% hepatectomy. Methods: Forty rats were subjected to 70% hepatectomy and then ~106 mesenchymal stem cells (test group), or saline solution (control group), were infused into their livers via the portal vein. Each treatment group was divided into early and late subgroups (euthanized 3 d and 5 d following the operation, respectively). Group comparisons of Albumin, aminotransaminases (AST, ALT), and Alcaline Phosphatase (AP) levels, proliferative index (ki-67+ straining), and mitotic cell counts were conducted. Results: No significant differences in liver regeneration rate, number of mitoses, proliferative index, or serum levels of albumin, AST, or AP were observed. ALT levels were higher in the test group than in the control group (p

Published
2017
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3. Brazilian-Portuguese Validation Assessment of the Gastrointestinal Quality of Life Index for Patients After Laparoendoscopic Cholecystectomy

Author

Gaspar de Jesus Lopes Filho, Elesiário Marques Caetano, Marcelo Moura Linhares, Maria José Azevedo de Brito Rocha, Marcos Bosi Ferraz, Juliana Posegger Taveira, Carlos Toshinori Maeda, and Karin Romano Posegger

Subjects
medicine.medical_specialty, Brazilian Portuguese, Quality of life, business.industry, medicine.medical_treatment, General surgery, medicine, language, Surgery, Cholecystectomy, business, language.human_language
Abstract

Background: Cholelithiasis is currently one of the most common diagnosis in Brazil. The aim of this study was to validate the Gastrointestinal Quality of Life Index (GIQLI) as a quality-of-life (Qo...

Published
2022
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4. Brazilian-Portuguese Validation Assessment of the

Author

Karin Romano, Posegger, Carlos Toshinori, Maeda, Juliana Posegger, Taveira, Elesiário Marques, Caetano, Marcos Bosi, Ferraz, Maria José Azevedo, de Brito Rocha, Gaspar de Jesus, Lopes Filho, and Marcelo Moura, Linhares

Subjects
Adult, Portugal, Surveys and Questionnaires, Quality of Life, Humans, Reproducibility of Results, Cholecystectomy, Laparoscopy, Brazil
Published
2021

5. The role of minimally invasive hepatectomy for hilar and intrahepatic cholangiocarcinoma: A systematic review of the literature

Author

Nora Manoukian Forones, Carlos Toshinori Maeda, Marcelo Moura Linhares, Raphael L. C. Araujo, Gaspar de Jesus Lopes-Filho, Luciana C. Silva, Daniel Kitayama Shiraiwa, and Parisina F. D. C. Carvalho

Subjects
medicine.medical_specialty, medicine.medical_treatment, Blood Loss, Surgical, 030230 surgery, Liver resections, Cholangiocarcinoma, 03 medical and health sciences, 0302 clinical medicine, Blood loss, medicine, Hepatectomy, Humans, Perihilar Cholangiocarcinoma, Laparoscopy, Intrahepatic Cholangiocarcinoma, medicine.diagnostic_test, business.industry, General Medicine, Oncology, Bile Duct Neoplasms, 030220 oncology & carcinogenesis, Lymph Node Excision, Surgery, Lymphadenectomy, Radiology, business
Abstract

Despite the fact laparoscopic liver resections (LLR) for cholangiocarcinoma is still limited, this systematic review addressed surgical and oncological outcomes of LLR to treat both perihilar cholangiocarcinoma (pCCA) and intrahepatic cholangiocarcinoma (iCCA). Five comparative and 20 noncomparative studies were found. Regarding iCCA, LLR had lower blood loss and less need for Pringle maneuver. However, open liver resections (OLR) were performed more for major hepatectomies, with better lymphadenectomy rates and higher number of harvested lymph nodes. High heterogeneity and selection bias were suggested for iCCA studies.

Published
2019

6. Experimental study of inflammatory response and collagen morphometry with different types of meshes

Author

Carlos Toshinori Maeda, Gaspar de Jesus Lopes-Filho, Marcelo Moura Linhares, and R. Artigani Neto

Subjects
Male, medicine.medical_specialty, Polymers, Inflammatory response, Expanded polytetrafluoroethylene, 030230 surgery, Prosthesis Implantation, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Incisional Hernia, Rats, Wistar, Inflammation, Wound Healing, business.industry, Incisional hernia repair, Significant difference, Surgical Mesh, Hernia, Ventral, Rats, Surgery, Polypropylene mesh, Disease Models, Animal, Point of delivery, 030220 oncology & carcinogenesis, Collagen, business
Abstract

To compare an inflammation score and collagen morphometry after incisional hernia repair with four different meshes at two time points. Four types of mesh were used to repair an abdominal wall incisional defect in Wistar rats: high-density polypropylene (HW/PP); low-density polypropylene (LW/PP); polypropylene mesh encapsulated with polydioxanone coated with oxidized cellulose (PP/CE); and expanded polytetrafluoroethylene (ePTFE). An inflammation score based on histological analysis and collagen morphometry was performed after 7 and 28 days after operation (POD). Compared to LW/PP group at 7 POD, HW/PP group had lower (p = 0.014) and PP/CE group had higher inflammation scores (p = 0.001). At 28 POD, higher scores were seen in all the other groups compared to the LW/PP group (HW/PP, p = 0.046; PP/CE, p

Published
2016
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7. Does mesenchymal stem cell improve the liver regeneration after the 70% hepatectomy?

Author

Rogério Aoki Fuziy, Marcelo Moura Linhares, Valéria P. Lanzoni, Ana Karina Soares Alves, Carlos Toshinori Maeda, Gaspar de Jesus Lopes, and Rita Maria Aparecida Monteiro Moura Franco

Subjects
Male, Time Factors, Proliferative index, RD1-811, medicine.medical_treatment, Phosphatase, Cell- and Tissue-Based Therapy, Mesenchymal Stem Cell Transplantation, Andrology, 03 medical and health sciences, 0302 clinical medicine, medicine, Animals, Hepatectomy, Rats, Wistar, Saline, Cell Proliferation, business.industry, Mesenchymal stem cell, Albumin, Liver regeneration, Liver Regeneration, Rats, 030220 oncology & carcinogenesis, Injections, Intravenous, Models, Animal, 030211 gastroenterology & hepatology, Surgery, Liver function, business
Abstract

Purpose: To evaluate the effects of mesenchymal stem cells on liver regeneration in rats following a 70% hepatectomy. Methods: Forty rats were subjected to 70% hepatectomy and then ~106 mesenchymal stem cells (test group), or saline solution (control group), were infused into their livers via the portal vein. Each treatment group was divided into early and late subgroups (euthanized 3 d and 5 d following the operation, respectively). Group comparisons of Albumin, aminotransaminases (AST, ALT), and Alcaline Phosphatase (AP) levels, proliferative index (ki-67+ straining), and mitotic cell counts were conducted. Results: No significant differences in liver regeneration rate, number of mitoses, proliferative index, or serum levels of albumin, AST, or AP were observed. ALT levels were higher in the test group than in the control group (p

Published
2017

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