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Background: The objective of this study was to explore women’s experiences of a screen-and-treat approach with ablative therapy (referred to by the Spanish acronym TVT-TA) as a method of treatment following a positive HPV test in Iquitos, Peru. Methods: A total of 111 in-depth interviews were conducted with 47 HPV positive women who attended the TVT-TA procedure at a primary-level healthcare facility. Interviews were conducted immediately before, immediately after, and six-weeks after TVT-TA. Results: Most interviewed women reported experiencing moderate pain during ablative therapy and minimal pain immediately after and six weeks after ablative therapy. Women also stated that the pain was less intense than they had expected. The most common physical aftereffects of treatment were bleeding and vaginal odor. Women experienced oscillating emotions with fear upon receiving a positive HPV result, calming after hearing about ablative therapy treatment, worry about pain from the treatment itself, relaxation with counseling about the procedure, and relief following treatment. Conclusions: Nearly all participants emphasized that any pain experienced during TVT-TA was worth it, recommended that TVT-TA be expanded and available to more women, and stated that TVT-TA was faster and easier than expected. This study found that TVT-TA is a feasible and acceptable means of treating HPV according to the women receiving the treatment.

Epidemiología del cáncer ginecológico en el Perú. Programa nacional de promoción y prevención del cáncer. Rol de los centros de excelencia en la prevención y tratamiento del cáncer cervical. Validez científica de los argumentos contra la vacuna PVH. Cáncer de mama en el Perú.

De las 17,326 pacientes con cáncer de cuello uterino registradas en el INEN entre 1952 y 1979, 403 tenían 76 años o más al momento del diagnóstico (2.3%). El promedio de edad en este grupo fue 80.6 años y la edad más avanzada fue 99 años. El inicio de relaciones sexuales fue a los 19 años como promedio y el período de latencia 61 años, lo cual contrasta con los 16 y 7 años correspondientes al grupo de 123 pacientes menores de 25 años. La distribución por estadías clínicos mostró predominio de enfermedad avanzada en las añosas, aunque el compromiso parametrial (comparación entre estadías A y B) fue significativamente menor (p < 0.001) que en las jóvenes, posiblemente debido a cambios anatómicos involutivos. El carcinoma epidermoide fue el tipo predominante y significativamente más frecuente (98%) en las mayores de 76 años, con menor incidencia de adenocarcinoma y carcinoma mucoepidermoide. El infiltrado linioplasmocitario del estroma cervical fue más frecuente en las pacientes jóvenes, en las cuales se advirtió una relación inversa entre esta reacción y la extensión de la enfermedad. La ausencia de estas características en las pacientes añosas podrían ser interpretadas como una disminución de la capacidad de respuesta frente a la agresión neoplásica.

El objeto de la presente comunicación es revisar algunos aportes de investigación llevados a cabo en el Perú acerca de la relación del virus del papiloma humano con el cáncer de cérvix.

ObjectiveCervical cancer is a preventable disease which causes significant morbidity and mortality, particularly in developing countries. Although technology for early detection continues to improve, prevention programs suffer from significant barriers. Community-based participatory research is an approach to research which focuses on collaboration with the community to surmount these barriers. The objective of this study was to evaluate the utility of community-based participatory research techniques in a mother-child screen/treat and vaccinate program for cervical cancer prevention in Manchay, Peru.Materials and MethodsHuman papillomavirus (HPV) self-sampling and cryotherapy were used for the screen/treat intervention, and the Gardasil vaccine was used for the vaccine intervention. Community health workers from Manchay participated in a 3-day educational course, designed by the research team. The community health workers then decided how to implement the interventions in their community. The success of the program was measured by (1) the ability of the community health workers to determine an implementation plan, (2) the successful use of research forms provided, (3) participation and retention rates, and (4) satisfaction of the participants.Results(1) The community health workers used a door-to-door approach through which participants were successfully registered and both interventions were successfully carried out; (2) registration forms, consent forms, and result forms were used correctly with minimal error; (3) screen/treat intervention: 97% of registered participants gave an HPV sample, 94% of HPV-positive women were treated, and 90% returned for 6-month follow-up; vaccine intervention: 95% of registered girls received the first vaccine, 97% of those received the second vaccine, and 93% the third; (4) 96% of participants in the screen/treat intervention reported high satisfaction.ConclusionsCommunity-based participatory research techniques successfully helped to implement a screen/treat and vaccinate cervical cancer prevention program in Manchay, Peru. These techniques may help overcome barriers to large-scale preventive health-care interventions.