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Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare type of non-Hodgkin T-cell lymphoma, recently defined in the 2016 World Health Organization (WHO) classification of lymphoid neoplasms. It occurs more commonly when textured implants are used and appears clinically as a late seroma. Cytologically, these lesions are composed of large atypical cells with pleomorphic nucleus and an immunophenotype positive for T cell markers and CD30, and negative for ALK1. We report a 56-years-old woman with breast implants who developed a periprosthetic seroma three years after surgery. A fine needle aspiration of the lesion was carried out. Cytology and the immunocytochemical study revealed cells compatible with BIA-ALCL. The flow cytometric study was negative. Excisional biopsy of the capsule was performed, observing that the neoplastic cells were confined to the inner surface of the capsule. Imaging studies did not find evidence of disseminated disease. The present case demonstrates the importance of the study of any late periprosthetic effusion, which can be performed using fine needle aspiration.

Breast implant-associated anaplastic large cell lymphoma (BIA-ALCL) is a rare type of non-Hodgkin T-cell lymphoma, recently defined in the 2016 World Health Organization (WHO) classification of lymphoid neoplasms. It occurs more commonly when textured implants are used and appears clinically as a late seroma. Cytologically, these lesions are composed of large atypical cells with pleomorphic nucleus and an immunophenotype positive for T cell markers and CD30, and negative for ALK1. We report a 56-years-old woman with breast implants who developed a periprosthetic seroma three years after surgery. A fine needle aspiration of the lesion was carried out. Cytology and the immunocytochemical study revealed cells compatible with BIA-ALCL. The flow cytometric study was negative. Excisional biopsy of the capsule was performed, observing that the neoplastic cells were confined to the inner surface of the capsule. Imaging studies did not find evidence of disseminated disease. The present case demonstrates the importance of the study of any late periprosthetic effusion, which can be performed using fine needle aspiration.

Scedosporium species can cause colonization, superficial and deep localized infection or systemic disease, especially in immunocompromised hosts. We report a case of localized infection due to Scedosporium apiospermum in a 47 year old woman, with previous nasal surgery. She consulted for recurrent mucopurulent post-nasal discharge not responding to antibiotics. Computed tomography showed opacification of right maxillary sinus. Surgery was performed to removed abnormal tissue from sinus; biopsy revealed chronic sinusitis with aggregate of tightly packed hyphae suggestive of filamentous fungi. The microbiology fungal culture reported Scedosporium apiospermum.

RESUMENSe presenta el caso clinico de una mujer de 33 anos con una leiomiomatosis peritoneal diseminada (LPD) diagnosticada durante cirugia por tumor anexial. Al siguiente ano se embaraza. Durante la cesarea efec-tuada a las 38 semanas, se observa una exacerbacion de la enfermedad con sospecha de malignizacion por lo que se efectua una histerectomia total mas salpingooforectomia bilateral y reseccion de solo algunos nodulos de la cavidad abdominal. La biopsia diferida confirma el diagnostico de LPD. A la fecha completo 8 anos de seguimiento sin evidencias clinicas ni imagenes de persistencia.PALABRAS CLAVE: Leiomiomatosis peritoneal diseminadaSUMMARYWe report the clinical case of 33 years-old woman with leiomyomatosis peritonealis disseminata (LPD) who-se diagnosis becomes evident during a surgery for adnexal tumor. The next year she gets pregnant. During the cesarean section performed at 38 weeks’ gestation, it is observed a disease exacerbation with malignant characteristics. Because of that, a total hysterectomy takes place. It is performed a bilateral salpingo-oopho-rectomy and resection of only some nodules of the abdominal cavity. The deferred biopsy confirms the LPD diagnosis. By this time she has completed 8 years of clinical follow-up without clinical evidences or images of persistence.KEY WORDS: Leiomyomatosis peritonealis disseminataINTRODUCCIONLa leiomiomatosis peritoneal diseminada (LPD) es una enfermedad poco frecuente con no mas de 100 casos reportados en la literatura mundial. Se caracteriza por el desarrollo de multiples leio-miomas en la cavidad peritoneal que semejan una enfermedad maligna. Se presenta en mujeres en edad fertil, y la sospecha preoperatoria es dificil. Generalmente el diagnostico se hace durante la cirugia por un tumor abdominal. El diagnostico defi-nitivo es histologico. El objetivo de esta comunicacion es presentar el manejo de un caso clinico de LPD y una revision de la literatura.CASO CLINICOMujer de 33 anos, multipara de 2 partos vagina-les, referida a la Unidad de Oncologia Ginecologica del Hospital San Juan de Dios, en julio de 1998, con diagnostico de tumor ovarico izquierdo. En octubre de 1998 se efectuo una laparotomia exploradora en la que se describe: ovario izquierdo con tumor

We report a female newborn with a dystrophic epidermolysis bullosa. The diagnosis was made by electron microscopy of a bullous skin lesion. The importance of reaching a specific diagnosis is underscored. Close relatives can therefore be informed and educated about prognosis, etiology and the possibility of having new affected offspring. An accurate diagnosis can be reached through electronic microscopy or modern immunohistochemical techniques. Further complementary information given by conventional histology is required. A complete study is recommended to minimize errors in the intepretation of morphology (Rev Méd Chile 2004; 132: 614-8).