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Abstract The global crisis of the COVID-19 pandemic has highlighted the need for mathematical models to inform public health strategies. The present study introduces a novel six-compartment epidemiological model that uniquely incorporates a higher isolation rate for unreported symptomatic cases of COVID-19 compared to reported cases, aiming to enhance prediction accuracy and address the challenge of initial underreporting. Additionally, we employ optimal control theory to assess the cost-effectiveness of interventions and adapt these strategies to specific epidemiological scenarios, such as varying transmission rates and the presence of asymptomatic carriers. By applying this model to COVID-19 data from India (30 January 2020 to 24 November 2020), chosen to capture the initial outbreak and subsequent waves, we calculate a basic reproduction number of 2.147, indicating the high transmissibility of the virus during this period in India. A sensitivity analysis reveals the critical impact of detection rates and isolation measures on disease progression, showing the robustness of our model in estimating the basic reproduction number. Through optimal control simulations, we demonstrate that increasing isolation rates for unreported cases and enhancing detection reduces the spread of COVID-19. Furthermore, our cost-effectiveness analysis establishes that a combined strategy of isolation and treatment is both more effective and economically viable. This research offers novel insights into the efficacy of non-pharmaceutical interventions, providing a tool for strategizing public health interventions and advancing our understanding of infectious disease dynamics.

In applied and computational mathematics, quaternions are fundamental in representing three-dimensional rotations. However, specific types of quaternionic linear matrix equations remain few explored. This study introduces new quaternionic linear matrix equations and their necessary and sufficient conditions for solvability. We employ a methodology involving lemmas and ranks of coefficient matrices to develop a novel algorithm. This algorithm is validated through numerical examples, showing its applications in advanced fields. In control theory, these equations are used for analyzing control systems, particularly for spacecraft attitude control in aerospace engineering and for control of arms in robotics. In quantum computing, quaternionic equations model quantum gates and transformations, which are important for algorithms and error correction, contributing to the development of fault-tolerant quantum computers. In signal processing, these equations enhance multidimensional signal filtering and noise reduction, with applications in color image processing and radar signal analysis. We extend our study to include cases of $ \eta $-Hermitian and i-Hermitian solutions. Our work represents an advancement in applied mathematics, providing computational methods for solving quaternionic matrix equations and expanding their practical applications.

Selecting the right actuator for a portable exoskeleton involves a comprehensive evaluation of various design characteristics. In this study, we introduce a methodology for actuator selection based on specific tasks, enhancing the practical adoption of portable exoskeletons. By examining a range of candidate actuators designed for lower limb exoskeletons, our objective is to engineer a system that is both lightweight and power-efficient. These candidate actuators, developed by integrating diverse motors and transmission systems, were rigorously tested against defined tasks. Our methodology, applied to an assistive exoskeleton catered to the elderly, showed its potential in tailoring an efficient system with matching capabilities. The obtained results indicated that the ideal configuration achieved reductions in weight and power requirements by 35% and 80%, respectively. The present research delineates a strategic approach for actuator selection in portable exoskeletons, contributing to the evolution of high-performing assistive devices.

Decision-making in real-world scenarios faces uncertainty. Fuzzy theory has been a means to represent such uncertainty. In this study, we propose an approach that incorporates bipolarity into multi-criteria decision-making processes applied to digital marketing. The proposal considers both the positive and negative dimensions of data, leading to better-informed decisions. Our contribution integrates bipolarity into Pythagorean fuzzy matrices, a framework that broadens the utility of bipolar fuzzy theory. Through computational experimentation, we identify the most effective strategy for digital marketing platforms. When compared to existing techniques, our approach shows advantages, underlining its potential to improve decision-making in uncertain scenarios and offering insights for businesses that refine their digital marketing strategies.

Many studies have been performed in different regions of the world as a result of the COVID-19 pandemic. In this work, we perform a statistical study related to the number of vaccinated cases and the number of deaths due to COVID-19 in ten South American countries. Our objective is to group countries according to the aforementioned variables. Once the groups of countries are built, they are characterized based on common properties of countries in the same group and differences between countries that are in different groups. Countries are grouped using principal component analysis and K-means analysis. These methods are combined in a single procedure that we propose for the classification of the countries. Regarding both variables, the countries were classified into three groups. Political decisions, availability of resources, bargaining power with suppliers and health infrastructure among others are some of the factors that can affect both the vaccination process and the timely care of infected people to avoid death. In general, the countries acted in a timely manner in relation to the vaccination of their citizens with the exception of two countries. Regarding the number of deaths, all countries reached peaks at some point in the study period.

In this study, an internet of things (IoT)-enabled fuzzy intelligent system is introduced for the remote monitoring, diagnosis, and prescription of treatment for patients with COVID-19. The main objective of the present study is to develop an integrated tool that combines IoT and fuzzy logic to provide timely healthcare and diagnosis within a smart framework. This system tracks patients' health by utilizing an Arduino microcontroller, a small and affordable computer that reads data from various sensors, to gather data. Once collected, the data are processed, analyzed, and transmitted to a web page for remote access via an IoT-compatible Wi-Fi module. In cases of emergencies, such as abnormal blood pressure, cardiac issues, glucose levels, or temperature, immediate action can be taken to monitor the health of critical COVID-19 patients in isolation. The system employs fuzzy logic to recommend medical treatments for patients. Sudden changes in these medical conditions are remotely reported through a web page to healthcare providers, relatives, or friends. This intelligent system assists healthcare professionals in making informed decisions based on the patient's condition.

In this article, we build a repetitive magic square by multiplying four elements. This square is a matrix with its corresponding elements. The elements of this matrix that take different values allow us to obtain Ramanujan's number 1729 as its multiplicative magic constant. The additive magic constant of the square is the number 40. The elements of these magic constants form an arithmetic progression. An algorithm to build magic squares is also proposed.

Petrochemical and dairy industries, waste management, and paper manufacturing fall under the category of process industries where flow and liquid control are essential. Even when liquids are mixed or chemically treated in interconnected tanks, the fluid and flow should constantly be observed and controlled, especially when dealing with nonlinearity and imperfect plant models. In this study, we propose a nonlinear dynamic multiple-input multiple-output (MIMO) plant model. This model is then transformed through linearization, a technique frequently utilized in the analysis and modeling of fractional processes, and decoupling for decentralized fixed-structure H-infinity robust control design. Simulation tests based on MATLAB and SIMULINK are subsequently executed. Numerous assessments are conducted to evaluate tracking performance, external disturbance rejection, and plant parameter fluctuations to gauge the effectiveness of the proposed model. The objective of this work is to provide a framework that anticipates potential outcomes, paving the way for implementing a reliable controller synthesis for MIMO-connected tanks in real-world scenarios.

The continuous Bernoulli distribution is defined on the unit interval and has a unique property related to fractiles. A fractile is a position on a probability density function where the corresponding surface is a fixed proportion. This article presents the derivation of properties of the continuous Bernoulli distribution and formulates a fractile or quantile regression model for a unit response using the exponentiated continuous Bernoulli distribution. Monte Carlo simulation studies evaluate the performance of point and interval estimators for both the continuous Bernoulli distribution and the fractile regression model. Real-world datasets from science and education are analyzed to illustrate the modeling abilities of the continuous Bernoulli distribution and the exponentiated continuous Bernoulli quantile regression model.

In this paper, we introduce a SIVR model using the Laplace Adomian decomposition. This model focuses on a new trend in mathematical epidemiology dedicated to studying the characteristics of vaccination of infected communities. We analyze the epidemiological parameters using equilibrium stability and numerical analysis techniques. New mathematical strategies are also applied to establish our epidemic model, which is a pandemic model as well. In addition, we mathematically establish the chance for the next wave of any pandemic disease and show that a consistent vaccination strategy could control it. Our proposal is the first model introducing a vaccination strategy to actively infected cases. We are sure this work will serve as the basis for future research on COVID-19 and pandemic diseases since our study also considers the vaccinated population.

In this article, we propose a comparative study between two models that can be used by researchers for the analysis of survival data: (i) the Weibull regression model and (ii) the random survival forest (RSF) model. The models are compared considering the error rate, the performance of the model through the Harrell C-index, and the identification of the relevant variables for survival prediction. A statistical analysis of a data set from the Heart Institute of the University of São Paulo, Brazil, has been carried out. In the study, the length of stay of patients undergoing cardiac surgery, within the operating room, was used as the response variable. The obtained results show that the RSF model has less error rate for the training and testing data sets, at 23.55% and 20.31%, respectively, than the Weibull model, which has an error rate of 23.82%. Regarding the Harrell C-index, we obtain the values 0.76, 0.79, and 0.76, for the RSF and Weibull models, respectively. After the selection procedure, the Weibull model contains variables associated with the type of protocol and type of patient being statistically significant at 5%. The RSF model chooses age, type of patient, and type of protocol as relevant variables for prediction. We employ the randomForestSRC package of the R software to perform our data analysis and computational experiments. The proposal that we present has many applications in biology and medicine, which are discussed in the conclusions of this work.

Source coding maps elements from an information source to a sequence of alphabetic symbols. Then, the source symbols can be recovered exactly from the binary units. In this paper, we derive an approach that includes information variation in the source coding. The approach is more realistic than its standard version. We employ the Shannon entropy for coding the sequences of a source. Our approach is also helpful for short sequences when the central limit theorem does not apply. We rely on a quantifier of the information variation as a source. This quantifier corresponds to the second central moment of a random variable that measures the information content of a source symbol; that is, considering the standard deviation. An interpretation of typical sequences is also provided through this approach. We show how to use a binary memoryless source as an example. In addition, Monte Carlo simulation studies are conducted to evaluate the performance of our approach. We apply this approach to two real datasets related to purity and wheat prices in Brazil.

The focus on renewable energy is increasing globally to lessen reliance on conventional sources and fossil fuels. For renewable energy systems to work at their best and produce the desired results, precise feedback control is required. Microbial electrochemical cells (MEC) are a relatively new technology for renewable energy. In this study, we design and implement a model-based robust controller for a continuous MEC reactor. We compare its performance with those of traditional methods involving a proportional integral derivative (PID), H-infinity (H∞) controller and PID controller tuned by intelligent genetic algorithms. Recently, a dynamic model of a MEC continuous reactor was proposed, which describes the complex dynamics of MEC through a set of nonlinear differential equations. Until now, no model-based control approaches for MEC have been proposed. For optimal and robust output control of a continuous-reactor MEC system, we linearize the model to state a linear time-invariant (LTI) state-space representation at the nominal operating point. The LTI model is used to design four different types of controllers. The designed controllers and systems are simulated, and their performances are evaluated and compared for various operating conditions. Our findings show that a structured linear fractional transformation (LFT)-based H∞ control approach is much better than the other approaches against various performance parameters. The study provides numerous possibilities for control applications of continuous MEC reactor processes.

Direct current (DC) servo motors are central to many complex systems, such as electrical, electro-mechanical, and electro-hydraulic frameworks. In practice, these systems can have nonlinear characteristics and parameter variations. Accurate model representation and position tracking of DC motors are the main issues in many real systems, such as twin rotors, aircraft, airships, and robot manipulators. The precise position tracking of these systems has already been achieved using conventional H-infinity (H∞) controllers. However, the order and structure become more intricate when employing complex weights to shape the closed-loop system, which limits the current proposals. To overcome the above-mentioned limitations, in this article, we provide a precise angular position tracking of a DC servo motor utilizing an intelligent, robust linear controller based on a fixed-structure linear fractional transformation. The conventional H∞ controllers are based on the minimization of an unstructured linear fractional transformation objective function that leads to a complex design of these controllers. The main advantage of the proposed intelligent H∞ synthesis is the fixed and simple structure that increases its practical implementation. The methodology is formulated in the MATLAB software for the robust design of the proposed synthesis based on an intelligent fixed-structure H∞ optimization. Simulation results are compared with conventional H∞ and proportional-integral-derivative controllers. The results are also validated experimentally.

In diverse branches of mathematics, several inequalities have been studied and applied. In this article, we improve Furuta’s inequality. Subsequently, we apply this improvement to obtain new radius inequalities that not been reported in the current literature. Numerical examples illustrate the main findings.

Determining success factors for managing supply chains is a relevant aspect for companies. Then, modeling the relationship between inventory cost savings and supply chain success factors is a route for stating such a determination. This is particularly important in pharmacies and food nutrition services (FNS), where the advances made on this topic are still scarce. In this article, we propose and formulate a robust compromise (RoCo) multi-criteria model based on non-linear programming and time-dependent demand. The novelty of our proposal is in defining a score that allows us to measure the mentioned success factors in a simple way, in meeting together all three elements (RoCo multi-criteria, non-linear programming, and time-dependent demand) to state a new model, and in applying it to pharmacies and FNS. This model relates inventory cost savings for pharmacy/FNS and success factors across their supply chains. Savings of inventory costs are predicted by lot sizes to be purchased and computed by comparing optimal and true inventory costs. We utilize a system that records the movements and costs of products to collect the data. Factors, such as purchasing organization, economies of scale, and synchronized supply, are assumed using the purchase system, with these factors ranked on a Likert scale. We consider multilevel relationships between savings obtained for 79 pharmacy/FNS products, and success factor scores according to these products. To deal with the endogeneity bias of the relationships proposed, internal instrumental variables are employed by utilizing generalized statistical moments. Among our main conclusions, we state that the greatest cost savings obtained from inventory models are directly associated with low-success supply chain factors. In this association, the success factors operate as endogenous variables, with respect to inventory cost savings, given the simultaneity of their relationship with cost savings when inventory decision-making.

Different types of mathematical inequalities have been largely analyzed and employed. In this paper, we introduce improvements to some Ostrowski type inequalities and present their corresponding proofs. The presented proofs are based on applying the celebrated Hayashi inequality to certain functions. We provide examples that show these improvements. Illustrations of the obtained results are stated in a probability framework.

In this paper, we study a type of disease that unknowingly spreads for a long time, but by default, spreads only to a minimal population. This disease is not usually fatal and often goes unnoticed. We propose and derive a novel epidemic mathematical model to describe such a disease, utilizing a fractional differential system under the Atangana–Baleanu–Caputo derivative. This model deals with the transmission between susceptible, exposed, infected, and recovered classes. After formulating the model, equilibrium points as well as stability and feasibility analyses are stated. Then, we present results concerning the existence of positivity in the solutions and a sensitivity analysis. Consequently, computational experiments are conducted and discussed via proper criteria. From our experimental results, we find that the loss and regain of immunity result in the gain and loss of infections. Epidemic models can be linked to symmetry and asymmetry from distinct points of view. By using our novel approach, much research may be expected in epidemiology and other areas, particularly concerning COVID-19, to state how immunity develops after being infected by this virus.

Despite the increasing amount of research on social media, there are few studies on the use of WhatsApp to assess academic performance. Surprisingly, students use social media during lectures, causing a problem. According to the literature, students utilize WhatsApp throughout academic activities where it is prohibited. Researchers and policymakers must pay attention to this problem to understand its impact on academic achievement. In this paper, by using multivariate statistical methods, we investigate the impact of WhatsApp use on academic performance. We construct a questionnaire for this investigation and apply it to a case study based on a sample of 258 students of management from India. We determine the prevalence of WhatsApp employment among these students and note that many of them utilize the app for academic purposes. We found a positive association between time spent on WhatsApp and students’ grade point average (GPA) based on factor, principal component, correlation, and chi-square analyses. Answering questions on the app in class is related to the program’s ability to help students learn. More use of the app in class leads to a lower GPA. However, sometimes, using the app might help students learn and perform better. We identify that many students disseminate materials through the app for academic purposes, contributing to their academic performance. Furthermore, this app is utilized for communicating with their teachers. Computations were carried out with the R and SPSS software.

Governments must consider different issues when deciding on the location of healthcare centers. In addition to the costs of opening such centers, three further elements should be addressed: accessibility, demand, and equity. Such locations must be chosen to meet the corresponding demand, so that they guarantee a socially equitable distribution, and to ensure that they are accessible to a sufficient degree. The location of the centers must be chosen from a set of possible facilities to guarantee certain minimum standards for the operational viability of the centers. Since the set of potential locations does not necessarily cover the demand of all geographical zones, the efficiency criterion must be maximized. However, the efficient distribution of resources does not necessarily meet the equity criterion. Thus, decision-makers must consider the trade-off between these two criteria: efficiency and equity. The described problem corresponds to the challenge that governments face in seeking to minimize the impact of the pandemic on citizens, where healthcare centers may be either public hospitals that care for COVID-19 patients or vaccination points. In this paper, we focus on the problem of a zone-divided region requiring the localization of healthcare centers. We propose a non-linear programming model to solve this problem based on a coverage formula using the Gini index to measure equity and accessibility. Then, we consider an approach using epsilon constraints that makes this problem solvable with mixed integer linear computations at each iteration. A simulation algorithm is also considered to generate problem instances, while computational experiments are carried out to show the potential use of the proposed mathematical programming model. The results show that the spatial distribution influences the coverage level of the healthcare system. Nevertheless, this distribution does not reduce inequity at accessible healthcare centers, as the distribution of the supply of health centers must be incorporated into the decision-making process.

In this paper, we propose a new privatization mechanism based on a naive theory of a perturbation on a probability using wavelets, such as a noise perturbs the signal of a digital image sensor. Wavelets are employed to extract information from a wide range of types of data, including audio signals and images often related to sensors, as unstructured data. Specifically, the cumulative wavelet integral function is defined to build the perturbation on a probability with the help of this function. We show that an arbitrary distribution function additively perturbed is still a distribution function, which can be seen as a privatized distribution, with the privatization mechanism being a wavelet function. Thus, we offer a mathematical method for choosing a suitable probability distribution for data by starting from some guessed initial distribution. Examples of the proposed method are discussed. Computational experiments were carried out using a database-sensor and two related algorithms. Several knowledge areas can benefit from the new approach proposed in this investigation. The areas of artificial intelligence, machine learning, and deep learning constantly need techniques for data fitting, whose areas are closely related to sensors. Therefore, we believe that the proposed privatization mechanism is an important contribution to increasing the spectrum of existing techniques.

In a real-world situation produced under COVID-19 scenarios, predicting cryptocurrency returns accurately can be challenging. Such a prediction may be helpful to the daily economic and financial market. Unlike forecasting the cryptocurrency returns, we propose a new approach to predict whether the return classification would be in the first, second, third quartile, or any quantile of the gold price the next day. In this paper, we employ the support vector machine (SVM) algorithm for exploring the predictability of financial returns for the six major digital currencies selected from the list of top ten cryptocurrencies based on data collected through sensors. These currencies are Binance Coin, Bitcoin, Cardano, Dogecoin, Ethereum, and Ripple. Our study considers the pre-COVID-19 and ongoing COVID-19 periods. An algorithm that allows updated data analysis, based on the use of a sensor in the database, is also proposed. The results show strong evidence that the SVM is a robust technique for devising profitable trading strategies and can provide accurate results before and during the current pandemic. Our findings may be helpful for different stakeholders in understanding the cryptocurrency dynamics and in making better investment decisions, especially under adverse conditions and during times of uncertain environments such as in the COVID-19 pandemic.

In this paper, we propose and derive a Birnbaum–Saunders distribution to model bimodal data. This new distribution is obtained using the product of the standard Birnbaum–Saunders distribution and a polynomial function of the fourth degree. We study the mathematical and statistical properties of the bimodal Birnbaum–Saunders distribution, including probabilistic features and moments. Inference on its parameters is conducted using the estimation methods of moments and maximum likelihood. Based on the acceptance–rejection criterion, an algorithm is proposed to generate values of a random variable that follows the new bimodal Birnbaum–Saunders distribution. We carry out a simulation study using the Monte Carlo method to assess the statistical performance of the parameter estimators. Illustrations with real-world data sets from environmental and medical sciences are provided to show applications that can be of potential use in real problems.

In this paper, we extend the use of disjoint orthogonal components to three-way table analysis with the parallel factor analysis model. Traditional methods, such as scaling, orthogonality constraints, non-negativity constraints, and sparse techniques, do not guarantee that interpretable loading matrices are obtained in this model. We propose a novel heuristic algorithm that allows simple structure loading matrices to be obtained by calculating disjoint orthogonal components. This algorithm is also an alternative approach for solving the well-known degeneracy problem. We carry out computational experiments by utilizing simulated and real-world data to illustrate the benefits of the proposed algorithm.

Healthcare service centers must be sited in strategic locations that meet the immediate needs of patients. The current situation due to the COVID-19 pandemic makes this problem particularly relevant. Assume that each center corresponds to an assigned place for vaccination and that each center uses one or more vaccine brands/laboratories. Then, each patient could choose a center instead of another, because she/he may prefer the vaccine from a more reliable laboratory. This defines an order of preference that might depend on each patient who may not want to be vaccinated in a center where there are only her/his non-preferred vaccine brands. In countries where the vaccination process is considered successful, the order assigned by each patient to the vaccination centers is defined by incentives that local governments give to their population. These same incentives for foreign citizens are seen as a strategic decision to generate income from tourism. The simple plant/center location problem (SPLP) is a combinatorial approach that has been extensively studied. However, a less-known natural extension of it with order (SPLPO) has not been explored in the same depth. In this case, the size of the instances that can be solved is limited. The SPLPO considers an order of preference that patients have over a set of facilities to meet their demands. This order adds a new set of constraints in its formulation that increases the complexity of the problem to obtain an optimal solution. In this paper, we propose a new two-stage stochastic formulation for the SPLPO (2S-SPLPO) that mimics the mentioned pandemic situation, where the order of preference is treated as a random vector. We carry out computational experiments on simulated 2S-SPLPO instances to evaluate the performance of the new proposal. We apply an algorithm based on Lagrangian relaxation that has been shown to be efficient for large instances of the SPLPO. A potential application of this new algorithm to COVID-19 vaccination is discussed and explored based on sensor-related data. Two further algorithms are proposed to store the patient’s records in a data warehouse and generate 2S-SPLPO instances using sensors.

Governments have been challenged to provide timely medical care to face the COVID-19 pandemic. Under this pandemic, the demand for pharmaceutical products has changed significantly. Some of these products are in high demand, while, for others, their demand falls sharply. These changes in the random demand patterns are connected with changes in the skewness (asymmetry) and kurtosis of their data distribution. Such changes are critical to determining optimal lots and inventory costs. The lot-size model helps to make decisions based on probabilistic demand when calculating the optimal costs of supply using two-stage stochastic programming. The objective of this study is to evaluate how the skewness and kurtosis of the distribution of demand data, collected through sensors, affect the modeling of inventories of hospital pharmacy products helpful to treat COVID-19. The use of stochastic programming allows us to obtain results under demand uncertainty that are closer to reality. We carry out a simulation study to evaluate the performance of our methodology under different demand scenarios with diverse degrees of skewness and kurtosis. A case study in the field of hospital pharmacy with sensor-related COVID-19 data is also provided. An algorithm that permits us to use sensors when submitting requests for supplying pharmaceutical products in the hospital treatment of COVID-19 is designed. We show that the coefficients of skewness and kurtosis impact the total costs of inventory that involve order, purchase, holding, and shortage. We conclude that the asymmetry and kurtosis of the demand statistical distribution do not seem to affect the first-stage lot-size decisions. However, demand patterns with high positive skewness are related to significant increases in expected inventories on hand and shortage, increasing the costs of second-stage decisions. Thus, demand distributions that are highly asymmetrical to the right and leptokurtic favor high total costs in probabilistic lot-size systems.

In this paper, we group South American countries based on the number of infected cases and deaths due to COVID-19. The countries considered are: Argentina, Bolivia, Brazil, Chile, Colombia, Ecuador, Peru, Paraguay, Uruguay, and Venezuela. The data used are collected from a database of Johns Hopkins University, an institution that is dedicated to sensing and monitoring the evolution of the COVID-19 pandemic. A statistical analysis, based on principal components with modern and recent techniques, is conducted. Initially, utilizing the correlation matrix, standard components and varimax rotations are calculated. Then, by using disjoint components and functional components, the countries are grouped. An algorithm that allows us to keep the principal component analysis updated with a sensor in the data warehouse is designed. As reported in the conclusions, this grouping changes depending on the number of components considered, the type of principal component (standard, disjoint or functional) and the variable to be considered (infected cases or deaths). The results obtained are compared to the k-means technique. The COVID-19 cases and their deaths vary in the different countries due to diverse reasons, as reported in the conclusions.

One of the main drawbacks of the traditional methods for computing components in the three-way Tucker model is the complex structure of the final loading matrices preventing an easy interpretation of the obtained results. In this paper, we propose a heuristic algorithm for computing disjoint orthogonal components facilitating the analysis of three-way data and the interpretation of results. We observe in the computational experiments carried out that our novel algorithm ameliorates this drawback, generating final loading matrices with a simple structure and then easier to interpret. Illustrations with real data are provided to show potential applications of the algorithm.