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Objectives: To compare the accuracy of CAD-CAM and conventional guides in the static computer-assisted implant surgery (sCAIS) placement of distal free-end implants., Material and Methods: A prospective, controlled, and blinded quasi-experimental study was done involving 27 patients (76 implants) distributed into two groups according to the surgical guide manufacturing approach used: conventional (control group [CG]) or CAD-CAM (test group [TG]). The implants were planned in the software and the surgical guides were manufactured. Fully guided implant placement was carried out and the deviations were measured along with secondary variables as potential confounding factors. Descriptive analyses were performed on mean, standard deviation (SD), and interquartile range (IQR). In the comparative/inferential analysis hypothesis, contrasts were made of the quantitative and qualitative variables and multiple linear models were generated to adjust for the different confounding variables recorded., Results: Coronal horizontal deviation (CHD) was significantly greater in CG (1.52 mm) versus TG (1.04 mm) (p = 0.004). Apical horizontal deviation (AHD) in turn was 1.67 versus 1.46 mm, respectively; angular deviation was 2.87 versus 3.64; and vertical deviation was -0.1 versus -0.05 mm, with no significant differences between the groups (p > 0.05). A greater sleeve height, positioning in premolars versus molars, and the use of shorter implants, were associated with greater accuracy in relation to CHD and/or AHD (p < 0.05). The implant success rate at 1 year was 92.1%, 90.7% in TG, and 100% in CG, being statistically significant (p = 0.026) at the implant level, but not significant at the patient level., Conclusions: The CAD-CAM surgical guides proved to be more accurate than the conventional guides in the sCAIS placement of distal free-end implants, with statistically significant differences being observed in terms of CHD. All implant failures occurred in TG (6 implants/3 patients)., Trial Registration: ClinicalTrials.gov identifier: NCT06404385., (© 2024 The Author(s). Clinical Oral Implants Research published by John Wiley & Sons Ltd.)

The speed with which information from vision is transformed into working memory (WM) representations that resist interference from ongoing perception and cognition is the subject of conflicting results. Using distinct paradigms, researchers have arrived at estimates of the consolidation time course ranging from 25 ms to 1 s - a range of more than an order of magnitude. However, comparisons of consolidation duration across very different estimation paradigms rely on the implicit assumption that WM consolidation speed is a stable, structural constraint of the WM system. The extremely large variation in WM consolidation speed estimates across measurement approaches motivated the current work's goal of determining whether consolidation speed truly is a stable structural constraint of WM encoding, or instead might be under strategic control as suggested by some accounts. By manipulating the relative task priority of WM encoding and a subsequent sensorimotor decision in a dual-task paradigm, the current experiments demonstrate that the long duration of WM consolidation does not change as a result of task-specific strategies. These results allow comparison of WM consolidation across estimation approaches, are consistent with recent multi-phase WM consolidation models, and are consistent with consolidation duration being an inflexible structural limit., (© 2023. The Psychonomic Society, Inc.)

The attentional blink (AB) is often considered a top-down phenomenon because it is triggered by matching an initial target (T1) in a rapid serial visual presentation (RSVP) stream to a search template. However, the AB is modulated when targets are emotional, and is evoked when a task-irrelevant, emotional critical distractor (CDI) replaces T1. Neither manipulation fully captures the interplay between bottom-up and top-down attention in the AB: Valenced targets intrinsically conflate top-down and bottom-up attention. The CDI approach cannot manipulate second target (T2) valence, which is critical because valenced T2s can "break through" the AB (in the target-manipulation approach). The present research resolves this methodological challenge by indirectly measuring whether a purely bottom-up CDI can modulate report of a subsequent T2. This novel approach adds a valenced CDI to the "classic," two-target AB. Participants viewed RSVP streams containing a T1-CDI pair preceding a variable lag to T2. If the CDI's valence is sufficient to survive the AB, it should modulate T2 performance, indirectly signaling bottom-up capture by an emotional stimulus. Contrary to this prediction, CDI valence only affected the AB when CDIs were also extremely visually conspicuous. Thus, emotional valence alone is insufficient to modulate the AB.

An area within the ventral occipitotemporal cortex (vOTC), the "visual word form area" (VWFA), typically exhibits a strongly left-lateralized response to orthographic stimuli in skilled readers. While individual variation in VWFA lateralization has been observed, the behavioral significance of laterality differences remains unclear. Here, we test the hypothesis that differences in VWFA lateralization reflect differing preferences for holistic orthographic analysis. To examine this hypothesis, we implemented a new multivariate method that uses machine learning to assess functional lateralization, along with a traditional univariate lateralization method. We related these neural metrics to behavioral indices of holistic orthographic analysis (inversion sensitivity). The multivariate measure successfully detected the lateralization of orthographic processing in the VWFA, and as hypothesized, predicted behavioral differences in holistic orthographic analysis. An exploratory whole brain analysis identified further regions with a relationship between inversion sensitivity and lateralization: one near the junction of the inferior frontal and precentral sulci, and another along the superior temporal gyrus. We conclude that proficient native readers of English exhibit differences in cortical lateralization of the VWFA that have significant implications for reading behavior., (Copyright © 2019 Elsevier Inc. All rights reserved.)