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Your search keyword '"Caren Freel Meyers"' showing total 3 results
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3 results on '"Caren Freel Meyers"'

1. Semi-solid prodrug nanoparticles for long-acting delivery of water-soluble antiretroviral drugs within combination HIV therapies

Author

James J. Hobson, Amer Al-khouja, Paul Curley, David Meyers, Charles Flexner, Marco Siccardi, Andrew Owen, Caren Freel Meyers, and Steve P. Rannard

Subjects
Science
Abstract

Non-adherence to daily drug regimens is responsible for many negative clinical effects including drug resistance in life-long treatments for HIV. Here, the authors report on a HIV prodrug nanoparticle platform for long-acting sustained release of water-soluble drug compounds following injection.

Published
2019
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3. Revealing Substrate Promiscuity of 1-Deoxy-d-xylulose 5-Phosphate Synthase.

Author

Leighanne A. Brammer and Caren Freel Meyers

Subjects
*MONOSACCHARIDES, *ORGANIC synthesis, *PHOSPHATES, *CATALYSTS, *REACTION mechanisms (Chemistry), *PYRUVATES
Abstract

A study of DXP synthase has revealed flexibility in the acceptor substrate binding pocket for nonpolar substrates and has uncovered new details of the catalytic mechanism to show that pyruvate can act as both donor and acceptor substrate. [ABSTRACT FROM AUTHOR]

Published
2009
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