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Copyright of Portuguese Journal of Dermatology & Venereology is the property of Sociedade Portuguesa de Dermatologia & Venereologia and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)

A 56-year-old woman presented with abdominal, lumbar and thoracic livedo with 2 years of evolution, consisting of violaceous poikilodermatous patches with scattered petechiae on a base of erythema and telangiectasia, accompanied by diffuse and mild skin atrophy. Histological analysis revealed vasodilation of the superficial dermis and thickening of capillary walls, highlighted by periodic acid–Schiff stain and immunohistochemistry for collagen type IV. [ABSTRACT FROM AUTHOR]

A 74-year-old man, who was immunosuppressed, with a prior history of bronchial asthma and pulmonary sarcoidosis, treated with methotrexate (10 mg per week) and deflazacort (6 mg per day) was admitted to our hospital's Department of Infectious Diseases because of leishmaniasis of the epiglottis and vocal cords, with unequivocal pathology and serology, in order to initiate treatment with liposomal amphotericin B. He also presented with extensive skin lesions on the right upper limb and axilla. CPD questions Learning objective To gain knowledge about the diagnosis and treatment of a rare grain-forming infection, botryomycosis. [Extracted from the article]

The approach in a case of primary cutaneous ossification should include a biochemical study to exclude parathyroid hormone resistance, assessment for Albright hereditary osteodystrophy features and perform I GNAS i locus analysis. I GNAS i mutations may manifest as ectopic ossifications and hormone resistance depending on the allele affected. TSH resistance is often present at birth, while PTH resistance develops during childhood.4 Brachydactyly and obesity usually develop during childhood.4 Patients may also present resistance to gonadotropins and growth hormone-releasing hormone.5 PHP1B (OMIM#603233) was initially considered a phenotype of isolated renal PTH resistance, without other endocrine or physical abnormalities.5 However, TSH resistance and some AHO features have also been observed in PHP1B.4 PPHP (OMIM#612463) is diagnosed when typical AHO features are recognised, especially through the presence of brachydactyly type E, in the absence of PTH resistance. [Extracted from the article]

Cold-associated perniosis of the thighs corresponds to the entity classically known as "equestrian cold panniculitis." This is different from the acute cold-induced panniculitides (Haxthausen's adiponecrosis e frigore and ice popsicle panniculitis), in which there is a primary cold-induced injury with fat necrosis.[4] The main histologic feature is the presence of a superficial and deep perivascular and periadnexal lymphocytic infiltrate, similar to idiopathic perniosis. Discussion Since the histological findings were consistent with perniosis and given the topography of the lesions, the patient was diagnosed with cold-associated perniosis of the thighs. [Extracted from the article]

The article presents a case study of an old woman having annular erythematous plaques on the trunk. The woman had medical history of autoimmune thyroiditis, chronic obstructive pulmonary disease, as well as sinusitis. The patient underwent treatment using oral prednisolone each day in a tapering schedule.

(c), The immunohistochemical study revealed generalized positivity for CD30 (original magnification ×400) gl Lymphomatoid papulosis is defined as a chronic, recurrent, self-healing papulonecrotic, or papulonodular skin disease with histological features suggestive of a (CD-30 positive) malignant lymphoma. Lymphomatoid papulosis type E may present with large necrotic lesions, but histologically it is characterized by angioinvasion, which was not a feature in our case. Additionally, the patient also had two isolated nodular lesions on the lateral aspect of the left arm, with similar features (Fig. [Extracted from the article]

It belongs within the group of pseudosarcomatous lesions, which includes nodular fasciitis and proliferative fasciitis. Given the initial suspicion of a malignant proliferation, a computed tomography scan was performed, and it also revealed a complete resolution of the lesion four weeks later. (b) Superficial ulceration within the central area of the lesion gl Histopathological findings Skin biopsy revealed a proliferation of spindle-shaped and histiocytic cells in the deep dermis (Fig. [Extracted from the article]

Competing Interests: There are no conflicts of interest.