2,165 results on '"Cardiac tumors"'
Search Results
2. Cardiac metastasis of a soft tissue sarcoma: Case report and review of literature.
- Author
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Chetoui, Ayoub, Alouazen, Oula, Yazghi Martahe, Lamya, Oulad Amar, Asmae, and Alaoui Rachidi, Siham
- Subjects
- *
SARCOMA , *SQUAMOUS cell carcinoma , *PERICARDIAL effusion , *CARCINOMA , *HEART failure - Abstract
Cardiac metastases are the most frequent cardiac tumors. They can cause dysrhythmia, myocardial dysfunction, pericardial effusion, and heart failure. In decreasing order, the major primary malignancies associated with cardiac metastases are pleural mesothelioma, lung adenocarcinoma, undifferentiated carcinomas, lung squamous cell carcinoma, and breast carcinoma. Cardiac metastasis of sarcomas is uncommon, and only a limited number of cases have been found in literature. We report the case of an incidentally discovered cardiac metastasis when assessing the extension of a thigh mass in a 45-year-old man. [ABSTRACT FROM AUTHOR]
- Published
- 2025
- Full Text
- View/download PDF
3. Prenatally Diagnosed Cardiac Tumors and Tuberous Sclerosis Complex: A Single-Center Experience.
- Author
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Bakoš, Matija, Jelinek, Dora, Ćorić Ljoka, Ana, Sindičić Dessardo, Nada, Šarić, Dalibor, and Grizelj, Ruža
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BRAIN abnormalities ,RISK assessment ,MUSCLE tumors ,RESEARCH funding ,ACADEMIC medical centers ,EARLY detection of cancer ,PUERPERIUM ,PRENATAL diagnosis ,TUBEROUS sclerosis ,SYMPTOMS ,RETROSPECTIVE studies ,DESCRIPTIVE statistics ,MAGNETIC resonance imaging ,ARRHYTHMIA ,PANCREATIC tumors ,MEDICAL records ,ACQUISITION of data ,SEIZURES (Medicine) ,EPILEPSY ,CHILD development deviations ,QUALITY of life ,NEUROENDOCRINE tumors ,MTOR inhibitors ,URBAN hospitals ,HEART tumors ,COUNSELING ,CASE studies ,DISEASE risk factors ,DISEASE complications ,FETUS - Abstract
Background/Objectives: Cardiac rhabdomyoma (CR), the most frequently occurring fetal cardiac tumor, is often an early marker of tuberous sclerosis complex (TSC). This study evaluates outcomes of fetuses with prenatally diagnosed cardiac tumors managed at a single tertiary center. Methods: Medical records of fetuses diagnosed with cardiac tumors between 2009 and 2024 were retrospectively reviewed. Results: Sixteen cases were identified, with a median follow-up of 6.7 years. TSC was confirmed in 14 cases (88%). Multiple tumors were observed in 13 cases (81%), while 3 cases (19%) had solitary tumors. Both non-TSC cases involved solitary tumors. Cardiac complications (arrhythmias, conduction disorders, and hemodynamic abnormalities) occurred in 38% of cases prenatally and 69% postnatally, with larger tumor diameters significantly associated with complications (p = 0.02). No fetal hydrops or mortality occurred; however, one child died at age five due to a seizure. Postnatal tumor regression occurred in 56% of cases and complete regression in 38% by a median age of 2.3 years (range: 0.6–4.4). One tumor remained stable. Brain MRI revealed TSC-related changes in all TSC-affected patients except one, who had a developmental brain anomaly. Most TSC patients experienced epilepsy (71%) and developmental delays. Conclusion: While CRs are typically benign and regress spontaneously, their strong association with TSC highlights the importance of early diagnosis and family counseling. TSC-related epilepsy and psychomotor delays significantly impair the quality of life. Early mTOR inhibitor therapy offers promise in mitigating TSC-related complications and improving outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2025
- Full Text
- View/download PDF
4. Report of a giant invasive, wall-penetrating cardiac lipoma
- Author
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Jingze Zhu, Xiangyu Cao, Lei Chen, Junjie Song, Zhenya Shen, and Yunsheng Yu
- Subjects
Invasive cardiac lipoma ,Right atrium tumor ,Cardiac tumors ,Cardiovascular surgery ,Surgery ,RD1-811 ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Background Cardiac lipoma, a seldom-encountered benign tumor positioned beneath the endocardium, has the potential to impair electrophysiological functions. Diagnosis is principally based on imaging modalities. The uniqueness of this case lies in the tumor’s extension both internally and externally within the right atrium, rendering it of special interest. From a clinical standpoint, surgical removal is commonly advocated, wherein early intervention is pivotal in improving patients’ long-term prognoses. Case presentation A 35-year-old male was admitted to the hospital for treatment subsequent to the identification of a cardiac mass two days prior. Initial diagnostic assessments, encompassing CT scans and echocardiography, identified a space-occupying lesion within the heart. The patient underwent surgical excision of the cardiac tumor, utilizing mild hypothermic extracorporeal circulation via femoral vessel access. Intraoperative findings revealed adipose-like tissue of a “dumbbell-shaped” configuration situated both within and external to the right atrium, measuring approximately 8 cm*9 cm internally and 7 cm*6 cm externally, with the extracardiac mass being marginally larger. Postoperative pathological analysis confirmed a cardiac lipoma diagnosis. A follow-up echocardiogram conducted three months post-surgery exhibited no notable abnormalities. The patient is under continuous observation to monitor for any recurrence or potential long-term complications. Conclusion In this case report, we detail with precision a rare cardiac pathology manifested by an expansive infiltrative lipoma that pervades the endocardial and epicardial layers of the right atrium. After thorough preoperative diagnostic workup and evaluation, we contend that surgical intervention represents the optimal therapeutic approach for managing such conditions, with the goal of preemptively reducing the likelihood of cardiac compression or intracardiac obstruction.
- Published
- 2024
- Full Text
- View/download PDF
5. Clinical Pathophysiology and Research Highlights of Cardiac Angiosarcoma: Obligation for Immunogenetic Profiling to Understand Their Growth Pattern and Tailor Therapies
- Author
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Sri Harsha Kanuri and Yashashree Apparao Vegi
- Subjects
cardiac tumors ,malignant tumors ,sarcoma ,angiosarcoma ,pericardial tamponade ,bloody pericardial effusion ,Medicine - Abstract
Cardiac angiosarcoma is the most common malignant tumor of the heart. The typical clinical profile is a young male with 30–50 years of age. Due to varied clinical presentation, it can disguise common cardiovascular disorders, such as pericarditis, congestive cardiac failure, and angina. This can delay the diagnosis, thus allowing the tumor to progress to the advanced stage by the time it is detected. Depending on tumor grade and size, a combination of surgery, chemotherapy, and radiation is advocated. Despite aggressive management, these tumors have a propensity to recur, advance, and metastasize, thereby underscoring the treatment resistance commonly encountered with these tumors. Resultantly, most of the patients are more prone to have shorter survival time, worse clinical outcomes, and grave prognosis. Research efforts should be directed toward decoding the inherent immune-genetic traits of these aggressive tumors so that their rapid progression can be extensively repressed. So, we propounded basic and clinical research studies to grasp the genetic makeup of these tumors so that crafting novel therapeutic modalities for improving prognosis and survival interval in these malignant tumors can materialize.
- Published
- 2024
- Full Text
- View/download PDF
6. Surgical planning aided with 3D technologies for management of complex paracardiac tumors
- Author
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Camilo E. Pérez-Cualtán, Catalina Vargas-Acevedo, Juliana Sánchez-Posada, Camila Castro-Páez, Roberto Gutiérrez-Vargas, Julián F. Forero-Melo, Juan Manuel Pérez, Juan Carlos Briceño, Héctor M. Medina, Juan Pablo Umaña, Javier Navarro-Rueda, and Carlos Eduardo Guerrero-Chalela
- Subjects
Cardiac tumors ,Angiosarcoma ,3D-printing ,Surgery ,RD1-811 ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Background Accurate diagnosis and treatment of complex cardiac tumors poses challenges, particularly when surgical resection is considered. 3D reconstruction and printing appear as a novel approach to allow heart teams for optimal surgical and post operative care. Methods We report two patients with uncommon masses including a cardiac angiosarcoma (CAS) and a IgG4-related disease (IgG4-RD) with exclusive cardiac involvement. In both cases, three-dimensional (3D) reconstruction and 3D-printed models were utilized to aid the surgical team achieve optimal pre-operative planning. Both patients underwent ECG-gated cardiac computed tomography angiography (CCTA) imaging and, due to the complex anatomy of the masses, their large dimensions, proximity to vital cardiac and vascular structures, and unclear etiology, computational and 3D-printed models were created for surgical planning. An exploratory literature review of studies using 3D-printed models in surgical planning was performed. Results In case 1 (CAS), due to the size and extension of the mass to the right ventricular free wall, surgical intervention was not considered curative and, during thoracotomy, an open biopsy confirmed the imaging suspicion of CAS which guided the initiation of optimal medical treatment with chemotherapy and, after clear tumor retraction, the patient underwent a second surgical intervention, and during the 18 months of follow-up showed no signs of recurrence. In Case 2 (IgG4-RD), the patient underwent uncomplicated total surgical resection; this allowed directed treatment and, at 12 months follow-up, there are no signs of recurrence. Computational and 3D-printed models were used to plan the surgery and to confirm the findings. Limited studies have explored the use of 3D printing in the surgical planning of tumors. Conclusions We present two patients with uncommon cardiac tumors, highlighting the significant value of 3D models in the anatomical characterization and assessment of their extension. These models may be essential in surgical planning for complex cardiovascular cases and could provide more information than conventional imaging modalities. Further studies are needed to demonstrate the impact of 3D technologies in studying cardiac tumors.
- Published
- 2024
- Full Text
- View/download PDF
7. miRNAs in the diagnosis and therapy of cardiac and mediastinal tumors: a new dawn for cardio-oncology?
- Author
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Loreni, Francesco, Nenna, Antonio, Nappi, Francesco, Ferrisi, Chiara, Chello, Camilla, Lusini, Mario, Vincenzi, Bruno, Tonini, Giuseppe, and Chello, Massimo
- Abstract
Dysfunctions in miRNA production have been recently investigated as predictors of neoplasms and their therapeutic strategies. In this review, we summarize the available knowledge on miRNAs and cardiac tumors (such as myxoma) and mediastinal tumors (such as thymoma) and propose new avenues for future research. MiRNAs are crucial for cardiac development through the expression of cardiac transcription factors (miR-335-5p), hinder the cell cycle by modulating the activity of transcription factors (miR-126-3p, miR-320a), modulate the production of inflammatory factors such as interleukins (miR-217), and interfere with cell proliferation or apoptosis (miR-218, miR-634 and miR-122). Current and future research on miRNAs is essential, as a deep understanding could lead to a revolution in the field of diagnostics and prevention of neoplastic diseases. Article highlights miRNAs have been recently investigated in the field of cardiac and mediastinal tumors. This review intends to summarize existing literature and define new pathways for future research. The study of the complete mechanistic control of miRNA remains a crucial issue, as the proper understanding of signaling pathways is essential to forecast therapeutic implications. MiRNA signaling's direct impact on tumor pathophysiology, as well as the potential utility of miRNA-based therapies in mitigating tumor recurrence, underscores the significance of ongoing investigations in this area MiRNAs for diagnostic and preventive purposes in combating neoplastic diseases heralds a promising frontier for medical advancement, especially in preventing recurrencies. Collaborative models, such as engaging specialized heart team with oncologic consultations, adds a pragmatic dimension to optimizing patient care and outcomes [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
8. Report of a giant invasive, wall-penetrating cardiac lipoma.
- Author
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Zhu, Jingze, Cao, Xiangyu, Chen, Lei, Song, Junjie, Shen, Zhenya, and Yu, Yunsheng
- Subjects
RIGHT heart atrium ,TUMOR surgery ,BENIGN tumors ,SURGICAL excision ,CARDIOVASCULAR surgery ,ARTIFICIAL blood circulation - Abstract
Background: Cardiac lipoma, a seldom-encountered benign tumor positioned beneath the endocardium, has the potential to impair electrophysiological functions. Diagnosis is principally based on imaging modalities. The uniqueness of this case lies in the tumor's extension both internally and externally within the right atrium, rendering it of special interest. From a clinical standpoint, surgical removal is commonly advocated, wherein early intervention is pivotal in improving patients' long-term prognoses. Case presentation: A 35-year-old male was admitted to the hospital for treatment subsequent to the identification of a cardiac mass two days prior. Initial diagnostic assessments, encompassing CT scans and echocardiography, identified a space-occupying lesion within the heart. The patient underwent surgical excision of the cardiac tumor, utilizing mild hypothermic extracorporeal circulation via femoral vessel access. Intraoperative findings revealed adipose-like tissue of a "dumbbell-shaped" configuration situated both within and external to the right atrium, measuring approximately 8 cm*9 cm internally and 7 cm*6 cm externally, with the extracardiac mass being marginally larger. Postoperative pathological analysis confirmed a cardiac lipoma diagnosis. A follow-up echocardiogram conducted three months post-surgery exhibited no notable abnormalities. The patient is under continuous observation to monitor for any recurrence or potential long-term complications. Conclusion: In this case report, we detail with precision a rare cardiac pathology manifested by an expansive infiltrative lipoma that pervades the endocardial and epicardial layers of the right atrium. After thorough preoperative diagnostic workup and evaluation, we contend that surgical intervention represents the optimal therapeutic approach for managing such conditions, with the goal of preemptively reducing the likelihood of cardiac compression or intracardiac obstruction. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
9. A CLINICO PATHOLOGICAL STUDY OF CARDIAC MYXOMAS IN A TERTIARY CARE CENTRE.
- Author
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A. P., NISHKALA, PHILIPOSE, REBA, and GEORGE, LOVELY
- Subjects
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RIGHT heart atrium , *MEDICAL sciences , *ATRIAL septum , *LEFT heart atrium , *CEREBRAL infarction , *HEART tumors - Abstract
Background: Primary cardiac tumors are rare, and myxomas make up most of these tumors accounting for 30-50% of all primary heart tumours [1]. These commonly affect individuals between 3rd to 6th decades and have a female preponderance [2]. Despite a preference for the left atrium, any of the cardiac chambers can be involved. Myxomas have varied clinical presentations with the unusual feature being its potential to embolise and cause organ infarction [3]. The aim of this study is to analyse the clinical profile and histopathology findings of cardiac myxomas. Materials and Methods: This was a retrospective study done in the Department of Pathology, A. J. Institute of Medical Sciences & Research Centre, Mangalore for a duration of 8 years from January 2016 to December 2023. All the cases cardiac myxomas received in the histopathology laboratory were included in the study. Clinical history, radiology findings and histopathology of all the cases were reviewed and analysed. Results: A total number of 14 cardiac myxomas were encountered in the study. Females were more commonly affected (69.23%). The mean age of patients was 47.7 years. Most commonly patients presented with symptoms of cerebral infarction. Left atrium was the most common site followed by right atrium and interatrial septum. Myxomatous matrix and hemorrhage were the morphological features found in most cases. Conclusion: Cardiac myxomas though benign can cause life threatening embolic events. Hence, high index of suspicion and timely diagnosis is of utmost importance because it offers a scope for definitive treatment, i.e. surgical excision. [ABSTRACT FROM AUTHOR]
- Published
- 2024
10. Surgical planning aided with 3D technologies for management of complex paracardiac tumors.
- Author
-
Pérez-Cualtán, Camilo E., Vargas-Acevedo, Catalina, Sánchez-Posada, Juliana, Castro-Páez, Camila, Gutiérrez-Vargas, Roberto, Forero-Melo, Julián F., Pérez, Juan Manuel, Briceño, Juan Carlos, Medina, Héctor M., Umaña, Juan Pablo, Navarro-Rueda, Javier, and Guerrero-Chalela, Carlos Eduardo
- Subjects
TUMOR surgery ,COMPUTED tomography ,THERAPEUTICS ,SURGICAL excision - Abstract
Background: Accurate diagnosis and treatment of complex cardiac tumors poses challenges, particularly when surgical resection is considered. 3D reconstruction and printing appear as a novel approach to allow heart teams for optimal surgical and post operative care. Methods: We report two patients with uncommon masses including a cardiac angiosarcoma (CAS) and a IgG4-related disease (IgG4-RD) with exclusive cardiac involvement. In both cases, three-dimensional (3D) reconstruction and 3D-printed models were utilized to aid the surgical team achieve optimal pre-operative planning. Both patients underwent ECG-gated cardiac computed tomography angiography (CCTA) imaging and, due to the complex anatomy of the masses, their large dimensions, proximity to vital cardiac and vascular structures, and unclear etiology, computational and 3D-printed models were created for surgical planning. An exploratory literature review of studies using 3D-printed models in surgical planning was performed. Results: In case 1 (CAS), due to the size and extension of the mass to the right ventricular free wall, surgical intervention was not considered curative and, during thoracotomy, an open biopsy confirmed the imaging suspicion of CAS which guided the initiation of optimal medical treatment with chemotherapy and, after clear tumor retraction, the patient underwent a second surgical intervention, and during the 18 months of follow-up showed no signs of recurrence. In Case 2 (IgG4-RD), the patient underwent uncomplicated total surgical resection; this allowed directed treatment and, at 12 months follow-up, there are no signs of recurrence. Computational and 3D-printed models were used to plan the surgery and to confirm the findings. Limited studies have explored the use of 3D printing in the surgical planning of tumors. Conclusions: We present two patients with uncommon cardiac tumors, highlighting the significant value of 3D models in the anatomical characterization and assessment of their extension. These models may be essential in surgical planning for complex cardiovascular cases and could provide more information than conventional imaging modalities. Further studies are needed to demonstrate the impact of 3D technologies in studying cardiac tumors. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
11. Tumores hematolinfoides metastásicos al corazón y el dilema diagnóstico y terapéutico: una serie de casos.
- Author
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Carmona, Edgar, Mera-Martínez, Paulo F., Guerrero-Montero, Ayda G., Bastidas-Narváez, Andrea M., and Portillo-Miño, José D.
- Subjects
- *
HEART tumors , *TREATMENT effectiveness , *DERMATOFIBROMA , *NON-Hodgkin's lymphoma , *SURGICAL complications - Abstract
Introduction: Cardiac neoplasms are rare, in a postmortem analysis they are described between 0.01 to 0.1%; However, metastases to the heart are not as uncommon as one might assume. Secondary involvement of the pericardium, myocardium, great vessels, or coronary arteries has been reported: 0.7 and 3.5% in general autopsies and up to 9.1% in patients with known malignancies. Objective: To know the sociodemographic, clinical and therapeutic findings of patients with hematolymphoid tumors metastatic to the heart. Materials and methods: The sociodemographic and clinical characteristics of the patients are described, and clinical outcomes. A review of the complete medical records, laboratories, and diagnostic images is performed. A review of the literature was carried out in the main databases: PubMed, Scopus, Google Scholar, Web of Science, EMBASE, and Scielo in Spanish and English. This article is under the guidelines of the 2016 CARE. Results: 4 clinical cases of hematolymphoid neoplasia in the heart are presented. All 4 patients attended the hospital due to progressive dyspnea. Histopathology reported a B-cell precursor lymphoblastic lymphoma, high-grade pleomorphic angiosarcoma – high-grade malignant fibrous histiocytoma, non-Hodgkin lymphoma, and a high-grade angiosarcoma. All cases required surgery for cardiovascular complications such as cardiac tamponade or mass effect in the involved structures and chemotherapy and all patients had a good clinical outcome. Conclusions: Hematolymphoid tumors of the heart are rare. However, it is necessary to consider differential diagnoses for timely diagnosis and treatment since they can cause complications that can threaten the patients life. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
12. Cardiac rhabdomyoma: an uncommon culprit in sudden infant death.
- Author
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Mecklenburg, Kori L., Mitchell, Erik K., and Prahlow, Joseph A.
- Subjects
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SUDDEN infant death syndrome , *FORENSIC pathology , *SUDDEN death , *MYOCARDIUM , *AUTOPSY - Abstract
Sudden death in infants remains a common and poorly understood cause of childhood mortality in the USA. Pediatric cardiac tumors, although rare, may underlie some cases of unexplained sudden infant death. Autopsy is a crucial diagnostic step in these cases, as both gross and microscopic examination of the heart may uncover occult cardiac tumors. Rhabdomyomas are the most common cardiac tumors in childhood and may result in arrythmia and sudden death. We present a case of sudden death in a healthy 5-month-old infant which initially appeared "SIDS-like" until thorough histological analysis revealed an underlying cardiac rhabdomyoma. The case is of particular importance in that the gross examination of the heart was considered completely normal, and the tumor only involved certain portions of the heart microscopically. Had a single random section of myocardium been the only heart section examined microscopically, the diagnosis might have been missed. This case emphasizes the importance of thorough microscopic examination in infant cases, especially in cases where the heart appears grossly normal. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
13. Clinical Pathophysiology and Research Highlights of Cardiac Angiosarcoma: Obligation for Immunogenetic Profiling to Understand Their Growth Pattern and Tailor Therapies.
- Author
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Kanuri, Sri Harsha and Vegi, Yashashree Apparao
- Subjects
HEART tumors ,CARDIOVASCULAR diseases ,MEDICAL research ,SYMPTOMS ,DELAYED diagnosis - Abstract
Cardiac angiosarcoma is the most common malignant tumor of the heart. The typical clinical profile is a young male with 30–50 years of age. Due to varied clinical presentation, it can disguise common cardiovascular disorders, such as pericarditis, congestive cardiac failure, and angina. This can delay the diagnosis, thus allowing the tumor to progress to the advanced stage by the time it is detected. Depending on tumor grade and size, a combination of surgery, chemotherapy, and radiation is advocated. Despite aggressive management, these tumors have a propensity to recur, advance, and metastasize, thereby underscoring the treatment resistance commonly encountered with these tumors. Resultantly, most of the patients are more prone to have shorter survival time, worse clinical outcomes, and grave prognosis. Research efforts should be directed toward decoding the inherent immune-genetic traits of these aggressive tumors so that their rapid progression can be extensively repressed. So, we propounded basic and clinical research studies to grasp the genetic makeup of these tumors so that crafting novel therapeutic modalities for improving prognosis and survival interval in these malignant tumors can materialize. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
14. Metastatic choriocarcinoma to the heart and lung with successful multimodal management.
- Author
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Elhelw, Eslam, Alaaeldin, Fetoh, Elshalkamy, Mohamed, and Awad, Gehad
- Abstract
Cardiac tumors continue to be one of the most uncommon primary tumors. Secondary cardiac tumors are rare and occur in difficult instances. A multidisciplinary team is required for diagnosis and management. Within this case study, we present a 24-year-old female patient who experienced dyspnea and was diagnosed as having metastatic heart and lung choriocarcinoma that was effectively managed with heart surgery and chemotherapy. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
15. Confounding giant right atrial mass
- Author
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Sefa Tatar, Ahmet Taha Sahin, Mehmet Işık, and Niyazi Görmüş
- Subjects
Cardiac tumors ,Hydatid cyst ,Atrial myxomas ,Surgery ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Primary cardiac tumors are uncommon, with approximately 70–80% classified as benign. Myxomas constitute roughly half of all benign cardiac tumors, while cardiac hydatid cysts are exceptionally rare. Shortness of breath is a prominent symptom associated with these conditions. Echocardiography serves as the primary diagnostic tool, enabling early detection. The preferred course of action involves the surgical excision of the mass. Case presentation Our first case, a 51-year-old female presented to the cardiology outpatient clinic with complaints of shortness of breath and palpitations persisting for 3 months. Physical examination and tests were within normal limits. Echocardiography revealed a right atrial myxoma measuring 65 * 35 mm. Despite not affecting valve and ventricular functions, the mass was surgically resected. Our second case, a 55-year-old male admitted to the cardiology clinic with recurrent fever, shortness of breath, and chest pain. Physical examination and tests were normal. Echocardiography revealed an echogenic mass with a septate appearance adhering to the free wall of the right atrium. The patient, diagnosed with a hydatid cyst, underwent surgical resection. Conclusions We came across two different cases of RA masses which happened to be myxoma and hydatid cysts, and we managed accordingly. The right atrial myxomas typically present with nonspecific shortness of breath unless they cause valve obstruction. In cases where clinical findings suggest infection in the right atrial masses, it is essential to consider hydatid cyst as a potential diagnosis alongside the initial consideration of vegetation.
- Published
- 2024
- Full Text
- View/download PDF
16. Adherent Right Atrial Cardiac Lipoma with Obstructive Symptoms: An Unusual Case Report
- Author
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Ranjit Pawar, Rima Konsam, Anurag Garg, Ashish Dolas, Ankit Maheshwari, and Jayant Bajaj
- Subjects
cardiac lipoma ,cardiac tumors ,echocardiogram ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Benign cardiac tumors are rare, and cardiac lipomas constitute a small proportion. Since the majority of these lipomas vary in morphology, size, clinical presentation, and diagnosis, it is difficult to diagnose them until they become symptomatic. Management of large adherent cardiac lipomas presenting with obstructive symptoms can be challenging. It can be arduous to excise them completely, as they may involve vital structures and may sometimes need debulking only, leading to the possibility of recurring tumors. We report a case of a 60-year-old male with complaints of chest pain and dyspnea on exertion, diagnosed with a large right atrial mass, extensive involvement of the right atrial wall, and impingement on the tricuspid valve and was managed by surgical resection with a positive clinical result. This case highlights that obstructive or symptomatic cardiac lipomas can be effectively resected with favorable outcomes.
- Published
- 2024
- Full Text
- View/download PDF
17. Confounding giant right atrial mass.
- Author
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Tatar, Sefa, Sahin, Ahmet Taha, Işık, Mehmet, and Görmüş, Niyazi
- Abstract
Background: Primary cardiac tumors are uncommon, with approximately 70–80% classified as benign. Myxomas constitute roughly half of all benign cardiac tumors, while cardiac hydatid cysts are exceptionally rare. Shortness of breath is a prominent symptom associated with these conditions. Echocardiography serves as the primary diagnostic tool, enabling early detection. The preferred course of action involves the surgical excision of the mass. Case presentation: Our first case, a 51-year-old female presented to the cardiology outpatient clinic with complaints of shortness of breath and palpitations persisting for 3 months. Physical examination and tests were within normal limits. Echocardiography revealed a right atrial myxoma measuring 65 * 35 mm. Despite not affecting valve and ventricular functions, the mass was surgically resected. Our second case, a 55-year-old male admitted to the cardiology clinic with recurrent fever, shortness of breath, and chest pain. Physical examination and tests were normal. Echocardiography revealed an echogenic mass with a septate appearance adhering to the free wall of the right atrium. The patient, diagnosed with a hydatid cyst, underwent surgical resection. Conclusions: We came across two different cases of RA masses which happened to be myxoma and hydatid cysts, and we managed accordingly. The right atrial myxomas typically present with nonspecific shortness of breath unless they cause valve obstruction. In cases where clinical findings suggest infection in the right atrial masses, it is essential to consider hydatid cyst as a potential diagnosis alongside the initial consideration of vegetation. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
18. Adherent Right Atrial Cardiac Lipoma with Obstructive Symptoms: An Unusual Case Report.
- Author
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Pawar, Ranjit, Konsam, Rima, Garg, Anurag, Dolas, Ashish, Maheshwari, Ankit, and Bajaj, Jayant
- Subjects
TUMOR diagnosis ,TUMOR surgery ,CHEST pain ,CANCER relapse ,ELECTROCARDIOGRAPHY ,RIGHT heart atrium ,DYSPNEA ,CORONARY angiography - Abstract
Benign cardiac tumors are rare, and cardiac lipomas constitute a small proportion. Since the majority of these lipomas vary in morphology, size, clinical presentation, and diagnosis, it is difficult to diagnose them until they become symptomatic. Management of large adherent cardiac lipomas presenting with obstructive symptoms can be challenging. It can be arduous to excise them completely, as they may involve vital structures and may sometimes need debulking only, leading to the possibility of recurring tumors. We report a case of a 60-year-old male with complaints of chest pain and dyspnea on exertion, diagnosed with a large right atrial mass, extensive involvement of the right atrial wall, and impingement on the tricuspid valve and was managed by surgical resection with a positive clinical result. This case highlights that obstructive or symptomatic cardiac lipomas can be effectively resected with favorable outcomes. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
19. Cardiac Neoplasms
- Author
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Del Val, Fernando Ramirez, Reardon, Michael J., Eltorai, Adam E.M., Series Editor, Bloom, Jordan P., editor, and Sundt, Thoralf M., editor
- Published
- 2024
- Full Text
- View/download PDF
20. Complicated atrial myxoma with coro-cameral fistula arising from its feeding branch: a case report
- Author
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Jian-Qiang Li, Ping Dong, Qian-Li Wang, Xiao-Xia Li, Tu-Min Sha, Peng Zhang, Zhen-Qing Zhao, and Chao-Liang Liu
- Subjects
left atrial myxoma ,coronary artery fistula ,feeding artery rupture ,cardiac tumors ,atrial fibrillation ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
A 56-year-old man with a 5-year history of paroxysmal palpitations, which have worsened over the past year, was diagnosed with atrial fibrillation. During evaluation, transesophageal echocardiography revealed a left atrium (LA) tumoral mass attached to the atrial septal fossa ovale, with intra-tumoral blood flow and blood stream draining from the mass. Both coronary computed tomography angiography and coronary angiography demonstrated a coro-cameral fistula connection between the left circumflex artery (LCX) branch and the LA. In addition, they showed feeding arteries of the mass arising from the LCX. The patient underwent surgical resection of the LA mass and repair of the coronary artery fistula. Intraoperative exploration revealed a 1.7 cm × 1.0 cm jelly-like, brittle LA mass and confirmed a rupture of the supplying artery, leading to a coronary artery–left atrial fistula. Surgical ligation was executed to ensure complete sealing of the supplying coronary branch within the atrial septum. Histopathological examination confirmed the diagnosis of left atrial myxoma. The 6-month follow-up indicated no recurrence of the myxoma and restoration of sinus rhythm after radiofrequency ablation. In the literature, cases of a left circumflex artery branch–left atrial fistula due to rupture of the artery supplying a left atrial myxoma are rare.
- Published
- 2024
- Full Text
- View/download PDF
21. Childhood Cardiac Tumors Treatment (PDQ®)
- Published
- 2024
22. Clinical presentation, diagnostic evaluation, and management of undifferentiated/unclassified cardiac sarcoma: A case report and literature review
- Author
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Aynaz Mohammadi, Mohammad Mohammadi, Mahboubeh Pazoki, Mohammad reza Ayoubpour, Pegah Babaheidarian, Sam Zeraatian Nejad Davani, and Reza Ghaderi
- Subjects
Cardiac tumors ,Undifferentiated sarcoma ,Cardiac sarcomas ,Echocardiography ,Surgery ,Multimodal imaging ,Medical physics. Medical radiology. Nuclear medicine ,R895-920 - Abstract
This case report details a challenging instance of undifferentiated/unclassified cardiac sarcoma in a 28-year-old female, presenting with diverse symptoms like muscle weakness, shortness of breath, and hemoptysis. Diagnostic hurdles led to an initial misdiagnosis of granulomatosis with polyangiitis before discovering a sizable left atrial mass, ultimately diagnosed as high-grade undifferentiated/unclassified sarcoma. Despite initial surgical intervention, the patient's condition worsened, underscoring the complexities in managing such cases involving cardiac sarcomas. This case emphasizes the diagnostic complexities associated with primary cardiac sarcomas, particularly the challenges in achieving accurate diagnoses and formulating effective treatment strategies.
- Published
- 2024
- Full Text
- View/download PDF
23. Ventricular tachycardia as the main manifestation of primary cardiac lymphoma in a dog
- Author
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Romito, G., Marconato, L., Turba, M.E., and Morini, M.
- Published
- 2025
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24. Prenatally Diagnosed Cardiac Tumors and Tuberous Sclerosis Complex: A Single-Center Experience
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Matija Bakoš, Dora Jelinek, Ana Ćorić Ljoka, Nada Sindičić Dessardo, Dalibor Šarić, and Ruža Grizelj
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cardiac rhabdomyoma ,cardiac tumors ,prenatal diagnosis ,tuberous sclerosis complex ,mTOR inhibitors ,pancreatic neuroendocrine tumor ,Pediatrics ,RJ1-570 - Abstract
Background/Objectives: Cardiac rhabdomyoma (CR), the most frequently occurring fetal cardiac tumor, is often an early marker of tuberous sclerosis complex (TSC). This study evaluates outcomes of fetuses with prenatally diagnosed cardiac tumors managed at a single tertiary center. Methods: Medical records of fetuses diagnosed with cardiac tumors between 2009 and 2024 were retrospectively reviewed. Results: Sixteen cases were identified, with a median follow-up of 6.7 years. TSC was confirmed in 14 cases (88%). Multiple tumors were observed in 13 cases (81%), while 3 cases (19%) had solitary tumors. Both non-TSC cases involved solitary tumors. Cardiac complications (arrhythmias, conduction disorders, and hemodynamic abnormalities) occurred in 38% of cases prenatally and 69% postnatally, with larger tumor diameters significantly associated with complications (p = 0.02). No fetal hydrops or mortality occurred; however, one child died at age five due to a seizure. Postnatal tumor regression occurred in 56% of cases and complete regression in 38% by a median age of 2.3 years (range: 0.6–4.4). One tumor remained stable. Brain MRI revealed TSC-related changes in all TSC-affected patients except one, who had a developmental brain anomaly. Most TSC patients experienced epilepsy (71%) and developmental delays. Conclusion: While CRs are typically benign and regress spontaneously, their strong association with TSC highlights the importance of early diagnosis and family counseling. TSC-related epilepsy and psychomotor delays significantly impair the quality of life. Early mTOR inhibitor therapy offers promise in mitigating TSC-related complications and improving outcomes.
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- 2025
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25. Rheumatic heart disease of the mitral valve alongside the papillary fibroelastoma of the aortic valve: A case report.
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Khezerlouy Aghdam, Naser, Delkhah, Mitra, Danayi, Saeid, and Sobhi, Navid
- Subjects
- *
RHEUMATIC heart disease , *AORTIC valve , *HEART valve diseases , *MITRAL stenosis , *MITRAL valve , *SYMPTOMS - Abstract
Key Clinical Message: Besides thromboses, it's crucial to also consider the rare possibility of tumors like papillary fibroelastomas when evaluating worsening cardiopulmonary symptoms in patients with severe rheumatic mitral stenosis and atrial fibrillation. Cardiac papillary fibroelastoma is a rare and benign endocardial tumor typically found on the aortic valve. The simultaneous occurrence of rheumatic heart disease affecting the mitral valve and papillary fibroelastoma on the aortic valve is infrequent, with limited documented instances. This unique case can enhance our understanding of the clinical presentation, diagnostic approaches, management options, and implications for patient outcomes in these two conditions. We present the case of a 47‐year‐old woman who was admitted to the hospital due to worsening dyspnea and fatigue, during which time she discovered an aortic valve papillary fibroelastoma. Further investigations revealed two thrombi in her left atrium and left atrial appendage, along with significant rheumatic mitral valve stenosis. The patient underwent thrombectomy, mitral valve replacement, and valve‐sparing aortic valve tumor resection. Following surgery, the patient's recovery was unremarkable. This case report emphasizes the need for a comprehensive evaluation in patients with rheumatic mitral stenosis, considering all possible etiologies. While thrombi are typical in mitral stenosis and atrial fibrillation, the rare presence of tumors like papillary fibroelastomas should be recognized, underscoring the importance of further assessment when suspicion arises. Importantly, individuals with asymptomatic cardiac papillary fibroelastomas should undergo surgical treatment to minimize the potential risk of tumoral embolization. [ABSTRACT FROM AUTHOR]
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- 2024
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26. STEMI or not STEMI? A multimodality imaging approach to a challenging intracardiac mass with a tricky presentation.
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Piscitelli, Laura, Robles, Antonio Gianluca, Costantino, Roberto, Forte, Valentina, Romano, Silvio, Sciarra, Luigi, Bartolomucci, Francesco, and Rosario Chieppa, Domenico Riccardo
- Abstract
Cardiac tumors, due to the various clinical scenarios and their histological subtypes, are still challenging for clinicians. They are differentiated into primary and secondary. The latest are more common and are usually lung and breast cancers, melanomas, and lymphoma metastasis. We present a case of a 73-year-old woman, with a history of breast cancer 10 years earlier, admitted to Cath lab for an elevation of the ST-segment of the electrocardiogram, myocardial infarction. Echocardiogram showed a curious abnormality in the myocardial wall. Thanks to a multimodality imaging strategy, including contrast-enhanced echocardiography and cardiac magnetic resonance, characterization of the underlying pathology was clear and, thus, the appropriate management and therapy. This is the case of a cardiac metastatic tumor, whose certain diagnosis can only be made by myocardial biopsy – an invasive sample of heart tissue – unfortunately not available in our case. Alternatively, we puzzled data from two second-level imaging techniques: contrast-enhanced cardiac ultrasound and cardiac magnetic resonance, which allowed us to better evaluate the nature of this cardiac mass. The former gave information about its blood supply, the latter gave information about tissue characterization. In this paper, we show how a complete integration of data from clinical and a stepwise multimodality imaging-based approach may allow a diagnosis in a complex clinical case. Article highlights Cardiac tumor diagnosis, due to the various clinical scenarios and their histological subtypes, is still challenging for clinicians. Cardiac metastasis causing a thromboembolic ST-elevation myocardial infarction (STEMI) has been rarely reported. Even if the certainty of cardiac masses diagnosis - and in particular of cardiac tumors - is given only by histopathology; cardiac magnetic resonance may importantly improve diagnostic workup. In this particular scenario, the use of ultrasound-enhancing agents in echocardiography is an important tool for the assessment of myocardial mass perfusion. When histopathology exam is not possible, a stepwise multimodality imaging approach can lead to a fairly confident diagnosis. [ABSTRACT FROM AUTHOR]
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- 2024
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27. Primary cardiac sarcoma: demographics, genomic study correlation, and survival benefits of surgery with adjuvant therapy in U.S. population.
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Khan, Rozi, Sunthankar, Kathryn I., Yasinzai, Abdul Qahar Khan, Tareen, Bisma, Zarak, Muhammad Samsoor, Khan, Jaffar, Nasir, Hassan, Nakasaki, Manando, Jahangir, Eiman, Heneidi, Saleh, and Ullah, Asad
- Abstract
Background: Cardiac sarcomas are rare and aggressive tumors with little known about the demographics, genetics, or treatment outcomes. Objectives: The objectives of this study were to characterize the demographics, treatment modality, and survival associated with cardiac sarcomas and evaluate the potential for mutation-directed therapies. Methods: All cases from 2000 to 2018 of cardiac sarcoma were extracted from the SEER database. Genomic comparison utilized The Cancer Genome Atlas (TCGA) database, as well as reviews and re-analysis of past applicable genomic studies. Results: Cardiac sarcomas occurred most often in White patients, compared with national census data cardiac sarcomas occurred at a significantly higher rate in Asians. The majority of cases were undifferentiated (61.7%) and without distant metastases (71%). Surgery was the most common primary treatment modality and offered survival benefit (HR 0.391 (p = 0.001) that was most pronounced and sustained as compared to patients who received chemotherapy (HR 0.423 (p = 0.001) or radiation (HR 0.826 (p = 0.241) monotherapy. There was no difference in survival when stratified by race or sex; however, younger patients (< 50) had better survival. Genomics data on histologically undifferentiated cardiac sarcomas revealed a significant number were likely poorly differentiated pulmonary intimal sarcomas and angiosarcomas. Conclusions: Cardiac sarcoma is a rare disease with surgery continuing to be a cornerstone of therapy followed by traditional chemotherapy. Case studies have indicated the potential for therapies directed to specific genetic aberrations to improve survival for these patients and utilization of next-generation sequencing (NGS) will help improve both classification and these therapies for cardiac sarcoma patients. [ABSTRACT FROM AUTHOR]
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- 2024
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28. Primary intracardiac germ cell tumor
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Siddhi Chawla
- Subjects
cardiac tumors ,echocardiography ,intracardiac germ cell tumor ,magnetic resonance imaging ,pediatric cardiac tumors ,Medicine ,Pediatrics ,RJ1-570 ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
We present the echocardiography images in a 6 year old girl who presented with a history of scalp swelling after trivial trauma which was subsequently diagnosed as metastases from primary intracardiac germ cell tumour.
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- 2024
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29. Resección conservadora del fibroelastoma papilar: resultados y revisión de la literatura
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Audelio Guevara-Bonilla, Pasquale Maiorano, Laura Castillo-Pardo, Gregorio Laguna-Núñez, Elio Martín-Gutiérrez, Javier Gualis-Cardona, María J. Alonso-Porto, and Mario Castaño-Ruiz
- Subjects
Papillary fibroelastoma ,Cardiac tumors ,Cardiac valves ,Thromboembolism ,Medicine ,Surgery ,RD1-811 - Abstract
Resumen: Introducción y objetivos: El fibroelastoma papilar es un tumor cardiaco primario benigno localizado normalmente en el endocardio valvular, aunque es posible encontrarlo en otras estructuras endocárdicas. Según estudios recientes, podría ser el tumor cardiaco primario benigno más común. En un número importante de casos es asintomático, se diagnostica de manera incidental y, en caso de presentar clínica acompañante, se asocia a eventos cerebrovasculares tromboembólicos. Mostramos nuestra experiencia en el tratamiento quirúrgico del fibroelastoma papilar y se lleva a cabo una revisión bibliográfica de la literatura. Métodos: Estudio retrospectivo unicéntrico mediante le revisión de las historias clínicas de todos los pacientes diagnosticados de fibroelastoma papilar y tratados quirúrgicamente en nuestro Servicio. Resultados: Desde enero de 2016 hasta octubre de 2022 se intervinieron 14 pacientes, predominantemente varones, con una edad media de 61 ± 12,6 años. El diagnóstico se realizó en casi todos los casos mediante estudios previos a la cirugía. La mayoría de los tumores eran asintomáticos y se localizaron en la válvula aórtica. Ninguno precisó reemplazo o reparación valvular. En 5 casos (35,7%) se realizó crioablación concomitante del lecho tumoral. No hubo mortalidad quirúrgica. Tras 3,2 ± 2,22 años de seguimiento dos pacientes fallecieron de causas no cardiacas. No se han objetivado recidivas. Conclusiones: El tratamiento quirúrgico del fibroelastoma papilar es seguro y ofrece buenos resultados. La crioablación concomitante podría ser útil para conseguir una eliminación tumoral completa sin necesidad de recambio valvular, aunque es necesaria más evidencia. La realización de un registro multicéntrico permitiría un mayor conocimiento de esta patología. Abstract: Introduction and objectives: Papillary fibroelastoma is a benign primary cardiac tumor normally located in the valvular endocardium, although it can be found in other endocardial structures. According to recent studies, it could be the most common benign primary cardiac tumor. In a significant number of cases it is asymptomatic, diagnosed incidentally and, in symptomatic cases, usually they present as thromboembolic neurological events. We show our experience in the surgical treatment of papillary fibroelastoma and a review of the literature is performed. Methods: Single-center retrospective study by reviewing the medical records of all patients diagnosed with papillary fibroelastoma and surgically treated in our department. Results: From January 2016 to October 2022, 14 patients were operated on, predominantly men, with a mean age of 61 ± 12.6 years. The diagnosis was made mostly in almost all cases during the preoperative study for other indications. Most of the tumors were asymptomatic and were located in the aortic valve. No patient required valve replacement or repair. In 5 cases (35.7%) concomitant cryoablation was performed. There was no surgical mortality. After 3.2 ± 2.22 years of follow-up, two patients died of non-cardiac causes. No tumoral recurrences have been found. Conclusions: Surgical treatment of papillary fibroelastoma is safe and offers good short and mid-term results. Concomitant cryoablation might be useful to achieve complete tumor removal without the need for valve replacement, however more evidence is mandatory. The realization of a multicenter registry would allow a better knowledge of this tumors.
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- 2023
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30. Linfoma no Hodgkin y mixoma hallados incidentalmente en tumoración extirpada de la aurícula izquierda
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Rodrigo Díaz-Barreto and Beatriz Rufato
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Non-Hodgkin's lymphoma ,Cardiac tumors ,Left atrium ,Primary cardiac lymphoma ,Myxoma ,Medicine ,Surgery ,RD1-811 - Abstract
Resumen: Los tumores cardiacos son infrecuentes con una sintomatología muy variable. Representan 0,2% de todas las neoplasias en general. El linfoma cardiaco primario representa 1,3% de los tumores cardiacos primarios y 0,5% de los linfomas extranodales. Se define como un linfoma no Hodgkin (LNH) que afecta solo al corazón y/o el pericardio. El linfoma no Hodgkin difuso de células B grandes es la variante histológica más frecuente. Se presenta un caso clínico de un paciente masculino de 57 años de edad, sin patología de base que fue hospitalizado en el servicio de cardiología con el diagnóstico de infarto agudo de miocardio sin elevación del segmento ST; en una ecocardiografía transtorácica se constata una masa intracardiaca en aurícula izquierda. Abstract: Cardiac tumors are infrequent with highly variable symptoms. They represent 0.2% of all neoplasms in general. Primary cardiac lymphoma represents 1.3% of primary cardiac tumors and 0.5% of extranodal lymphomas. It is defined as a non-Hodgkin's lymphoma (NHL) that affects only the heart and/or the pericardium. Diffuse large B-cell non-Hodgkin's lymphoma is the most common histological variant. A clinical case of a 57-year-old male patient is presented, with no underlying pathology who was hospitalized in the cardiology service with a diagnosis of non-ST-segment elevation acute myocardial infarction; A transthoracic echocardiogram revealed an intracardiac mass in the left atrium.
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- 2023
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31. Reduced Risk of All-Cause, Cancer-, and Cardiovascular Disease-Related Mortality among Patients with Primary Malignant Cardiac Tumors Receiving Chemotherapy in the United States
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Duke Appiah, Carina R. Goodart, Grishma K. Kothari, Imo A. Ebong, and Chike C. Nwabuo
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cardiac tumors ,cardiovascular disease ,chemotherapy ,surgery ,survival ,mortality ,Neoplasms. Tumors. Oncology. Including cancer and carcinogens ,RC254-282 - Abstract
Primary malignant cardiac tumors (PMCTs) are rare but lethal neoplasms. There are limited evidence-based treatment guidelines for PMCTs. We evaluated the relation of chemotherapy with mortality outcomes in patients with PMCTs in the United States. Data were from patients aged ≥ 20 years from the Surveillance, Epidemiology, and End Results program who were diagnosed with PMCTs from 2000 to 2020. Cox regression, competing risk, and propensity score analyses were performed to estimate hazard ratios (HR) and confidence intervals (CI). About 53% of the 563 patients with PMCTs received chemotherapy as the first course of treatment. During a mean follow-up of 24.7 months (median: 10), 458 deaths occurred with 81.7% and 9.4% due to cancer and cardiovascular disease (CVD), respectively. In models adjusted for sociodemographic and clinico-pathophysiological factors including histology, receipt of chemotherapy was associated with low risk for all-cause (HR: 0.56, 95%CI: 0.45–0.69), cancer (HR: 0.63, 95%CI: 0.50–0.80) and CVD mortality (HR: 0.27, 95%CI: 0.12–0.58). Patients who had both chemotherapy and surgery had the lowest risk for all-cause and cancer mortality. This study suggests that the subpopulations of patients with PMCTs who receive chemotherapy may have better prognosis than those who do not receive this therapy regardless of histology.
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- 2023
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32. Metastatic Heart Cancer Misdiagnosed as Acute Myocardial Infarction
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Vintha, Ravi, Sethi, Prakrut Nishamanish, Tohid, Hassaan, editor, Baratta, Larry G., editor, and Maibach, Howard, editor
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- 2023
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33. Tratamiento de los tumores cardíacos infantiles (PDQ®)
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- 2024
34. Cardiac masses and the role of imaging in their diagnostic
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Roungos Alexandros E., Zăvoi Alexandra, Leonte Andreea, Bostan Mădălina M., Dabija Anca, Bitere Eugen, Sascău Radu A., and Stătescu Cristian
- Subjects
cardiac tumors ,myxoma ,atrial septal defect ,echocardiography ,tumoră cardiacă ,mixom ,defect septal atrial ,ecocardiografie ,Internal medicine ,RC31-1245 - Abstract
Myxomas are the most common primary tumors of the adult heart and should be considered in the differential diagnosis of intracavitary cardiac masses, along with thrombi and vegetations.
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- 2023
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35. Minimally-invasive approach via percutaneous femoral cannulation for the resection of intra-cardiac masses: a single center experience in the Middle-East
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Uthman Aluthman, Mohammed A. Ashour, Salman W. Bafageeh, Abivarma Chandrakumaran, Taraji S. Alrehaili, Osama A. Abdulrahman, Ahmed F. Elmahrouk, Shalan Alaamri, Saeed A. AlGhamdi, and Ahmed A. Jamjoom
- Subjects
Minimally invasive surgery ,Cardiac tumors ,Cardiac myxoma ,Angiosarcoma ,Minithoracotomy ,Middle East ,Surgery ,RD1-811 ,Anesthesiology ,RD78.3-87.3 - Abstract
Abstract Background Intra-cardiac masses are rare and challenging lesions with an overall incidence ranging of 0.02–0.2%. Minimally invasive approaches have been recently introduced for surgical resection of these lesions. Here, we evaluated our early experience using minimally invasive techniques in addressing intra-cardiac lesions. Methodology This is a retrospective descriptive study conducted between April 2018 to December 2020. All patients were diagnosed with cardiac tumors and treated via a right mini-thoracotomy with cardiopulmonary bypass through femoral cannulation at King Faisal Specialist Hospital and Research Centre, Jeddah. Results Myxoma was the most common pathology representing 46% of cases followed by thrombus (27%), leiomyoma (9%), lipoma (9%) and angiosarcoma (9%). All tumors were resected with negative margins. One patient was converted to open sternotomy. Tumor locations were in the right atrium, left atrium, and left ventricle in 5, 3, and 3 patients, respectively. The median ICU stay was 1.33 days. The median length of hospitalization was 5.7 days. There was no 30-days hospital mortality recorded in this cohort. Conclusion Our early experience shows that minimally invasive resection can be performed safely and effectively for intra-cardiac masses. The minimally invasive approach using a mini-thoracotomy with percutaneous femoral cannulation can be an effective alternative in resecting intra-cardiac masses that achieves clear margin resection, quick post-operative recovery, and low rates of recurrence for benign lesions.
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- 2023
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36. Case Report: Acute cerebral infarction caused by left atrial and right ventricular myxoma received emergency operation
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Chengbin Tang, Xianglong Gao, Tao Chen, Jun Shao, Tao Zhu, Xucai Zheng, and Chuanli Ren
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myxomas ,neurologic symptoms ,emergency operation ,case report ,cardiac tumors ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Cardiac myxoma is a rare etiology of ischemic stroke, especially in young people. We report a case of multiple myxomas in left atrium and right ventricle inducing acute cerebral infarction. No significant abnormalities were detected in the patient's preoperative laboratory examination. Following emergency surgery, the patient's prognosis was satisfactory, providing valuable empirical insight for the surgical management of acute cerebral infarction in individuals diagnosed with cardiac myxoma. Our objective is to heighten awareness regarding the evaluation and treatment of patients with acute cerebral infarction subsequent to early diagnosis of cardiac myxoma.
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- 2024
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37. Congenital Blood Cyst of a Child A case report and review of literature.
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Kaddoura, Rachid, El Rassi, Issam, Al Awadi, Zainab, and Kasem, Mohamed
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- *
PULMONARY valve , *CHILD patients , *CYSTS (Pathology) , *HEART valves - Abstract
Blood-filled cysts of the heart valves are frequently reported at postpartum autopsies of infants. They are seen as round nodules mostly in the paediatric age group in infants less than 2 months of age and disappear spontaneously within 6 months of life. We report a unique case of an 11-month-old girl who presented at a tertiary healthcare hospital in 2022 with a blood-filled cyst on the posterior leaflet of the pulmonary valve that was successfully treated. This case report highlights the characteristics and course of a paediatric patient with bloodfilled cysts. Further studies are yet needed to better understand the diagnostic approaches to blood-filled cysts as well as treatment modalities to fill the gap in clinical settings. [ABSTRACT FROM AUTHOR]
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- 2024
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38. Anesthetic management of a patient with incidental left atrial myxoma for proximal femur nailing: A case report.
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ANNE, NAMITA, ANANDASWAMY, TEJESH C., GOVINDSWAMY, SURESH, and RAVICHANDRAN, GOWSHIK
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- *
LEFT heart atrium , *MYXOMA , *FEMUR , *BLOOD pressure , *ANESTHETICS , *SURGICAL excision - Abstract
Cardiac myxomas are rare tumors with risks of cardiac outflow obstruction and embolic events. Surgical excision of the tumor at the earliest is the definitive treatment. We report the successful anesthetic management of a 65-year-old female patient with incidental left atrial myxoma for right proximal femur nailing. The patient was asymptomatic with no significant cardiac history. Since fracture reduction cannot be deferred for a prolonged period, the case was taken up under general anesthesia with invasive blood pressure monitoring. [ABSTRACT FROM AUTHOR]
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- 2024
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39. Echocardiographic Evaluation of Cardiac Masses.
- Author
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Kurnick, Adam, Akivis, Yonatan, Sabu, Jacob, and John, Sabu
- Abstract
Purpose of Review: Cardiac masses encompass a broad range of etiologies and are often initially revealed by echocardiography. The differential may change depending on the location of the mass and patients' medical history or presentation. It is important for clinicians to be aware of subtle visual characteristics on echocardiography in order to correctly diagnose the pathology. Methods: Patients who underwent transthoracic echocardiography and were found to have one or more cardiac masses between January 1, 2020, and May 15, 2023, were reviewed. Their demographic data, clinical presentation, medical history, imaging, and follow-up information were collected from hospital electronic medical records, de-identified, and used to complete this review paper. Summary: A detailed review of cardiac masses divided by cardiac chamber accompanied by real-world echocardiographic images from patients in a large inner city public hospital. We hope that this systematic review of cardiac masses with real-world echocardiographic images will help clinicians note subtle echocardiographic characteristics to aid in the diagnosis and treatment of cardiac masses. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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40. Reduced Risk of All-Cause, Cancer-, and Cardiovascular Disease-Related Mortality among Patients with Primary Malignant Cardiac Tumors Receiving Chemotherapy in the United States.
- Author
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Appiah, Duke, Goodart, Carina R., Kothari, Grishma K., Ebong, Imo A., and Nwabuo, Chike C.
- Subjects
CANCER chemotherapy ,CANCER-related mortality ,SOCIODEMOGRAPHIC factors ,CARDIOVASCULAR diseases ,MORTALITY ,DISEASE risk factors - Abstract
Primary malignant cardiac tumors (PMCTs) are rare but lethal neoplasms. There are limited evidence-based treatment guidelines for PMCTs. We evaluated the relation of chemotherapy with mortality outcomes in patients with PMCTs in the United States. Data were from patients aged ≥ 20 years from the Surveillance, Epidemiology, and End Results program who were diagnosed with PMCTs from 2000 to 2020. Cox regression, competing risk, and propensity score analyses were performed to estimate hazard ratios (HR) and confidence intervals (CI). About 53% of the 563 patients with PMCTs received chemotherapy as the first course of treatment. During a mean follow-up of 24.7 months (median: 10), 458 deaths occurred with 81.7% and 9.4% due to cancer and cardiovascular disease (CVD), respectively. In models adjusted for sociodemographic and clinico-pathophysiological factors including histology, receipt of chemotherapy was associated with low risk for all-cause (HR: 0.56, 95%CI: 0.45–0.69), cancer (HR: 0.63, 95%CI: 0.50–0.80) and CVD mortality (HR: 0.27, 95%CI: 0.12–0.58). Patients who had both chemotherapy and surgery had the lowest risk for all-cause and cancer mortality. This study suggests that the subpopulations of patients with PMCTs who receive chemotherapy may have better prognosis than those who do not receive this therapy regardless of histology. [ABSTRACT FROM AUTHOR]
- Published
- 2023
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41. Cardiac tumors in the pediatric population - surgical experience of four decades
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Stajević Mila, Ilić Slobodan, Parezanović Vojislav, Prijić Sergej, Milovanović Vladimir, Kuzmanović Miloš, Đuričić Slaviša, Dizdarević Ivan, Popović Saša, and Bisenić Dejan
- Subjects
cardiac tumors ,pediatrics ,surgical approach ,follow up ,Medicine - Abstract
Introduction/Objective. Although cardiac tumors in the pediatric population are found infrequently, their occurrence is constant and with occasional variations. The purpose of this study is to show our experience with surgical options of these masses in two leading national university-level pediatric centers over four decades. Methods. This retrospective study is presenting a total number of 24 surgically treated pediatric patients who have been operated on 1998–2020. There were 16 children with primary masses and eight children with metastatic cardiac tumors. Two patients with tumor-like intracardiac masses were not included in the series but had been mentioned as diagnostic challenges. Our patients did not have cardiac transplantation options. Results. The average age of our patients was five and a half years, and the most frequent operated tumor was the cardiac myxoma. Four children had neurological symptoms. There were two deaths, one in the primary tumor group and one metastatic patient misdiagnosed as a primary tumor in the early ages of our department. We had two recurrent cases, a girl with Carney complex, and an infant with an extremely rare form of cardiac malignancy after a myxoma extraction. One child required a permanent pacemaker insertion. Conclusion. Although rare, the pediatric cardiac tumors can be a source of different life-threatening conditions and lifelong sequelae. Therefore, special considerations should be paid to the diagnostic and surgical modalities of their treatment.
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- 2023
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42. Minimally-invasive approach via percutaneous femoral cannulation for the resection of intra-cardiac masses: a single center experience in the Middle-East.
- Author
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Aluthman, Uthman, Ashour, Mohammed A., Bafageeh, Salman W., Chandrakumaran, Abivarma, Alrehaili, Taraji S., Abdulrahman, Osama A., Elmahrouk, Ahmed F., Alaamri, Shalan, AlGhamdi, Saeed A., and Jamjoom, Ahmed A.
- Subjects
RIGHT heart atrium ,HEART tumors ,ANGIOSARCOMA ,CENTER of mass ,CATHETERIZATION ,SURGICAL margin ,LEFT heart atrium - Abstract
Background: Intra-cardiac masses are rare and challenging lesions with an overall incidence ranging of 0.02–0.2%. Minimally invasive approaches have been recently introduced for surgical resection of these lesions. Here, we evaluated our early experience using minimally invasive techniques in addressing intra-cardiac lesions. Methodology: This is a retrospective descriptive study conducted between April 2018 to December 2020. All patients were diagnosed with cardiac tumors and treated via a right mini-thoracotomy with cardiopulmonary bypass through femoral cannulation at King Faisal Specialist Hospital and Research Centre, Jeddah. Results: Myxoma was the most common pathology representing 46% of cases followed by thrombus (27%), leiomyoma (9%), lipoma (9%) and angiosarcoma (9%). All tumors were resected with negative margins. One patient was converted to open sternotomy. Tumor locations were in the right atrium, left atrium, and left ventricle in 5, 3, and 3 patients, respectively. The median ICU stay was 1.33 days. The median length of hospitalization was 5.7 days. There was no 30-days hospital mortality recorded in this cohort. Conclusion: Our early experience shows that minimally invasive resection can be performed safely and effectively for intra-cardiac masses. The minimally invasive approach using a mini-thoracotomy with percutaneous femoral cannulation can be an effective alternative in resecting intra-cardiac masses that achieves clear margin resection, quick post-operative recovery, and low rates of recurrence for benign lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2023
- Full Text
- View/download PDF
43. Ventricular fibrillation and arrhythmia associated with cardiac fibromas involving both ventricles in a 1.5-year-old girl.
- Author
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Farkaš, Daniel, Pisarčíková, Mária, Vasovčák, Peter, Crhová, Anna, Ginelliová, Alžbeta, Mistríková, Lucia, Fröhlichová, Lucia, and Farkašová Iannaccone, Silvia
- Abstract
Copyright of Rechtsmedizin is the property of Springer Nature and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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- 2023
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44. Heart tumors - classification, diagnosis and methods of treatment
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Adriana Misiło, Krzysztof Olczyk, Monika Sosna, and Krzysztof Mordoń
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cardiac tumors ,malignant ,benign tumor ,Education ,Sports ,GV557-1198.995 ,Medicine - Abstract
Heart tumors are a rare oncological problem. Nevertheless, they are an important element of cardio-oncology that should not be forgotten. The development of imaging techniques has made it possible to increase the probability of making a diagnosis in a non-invasive way. Despite the development of techniques such as computed tomography, magnetic resonance imaging or positron emission tomography, histopathological examination still remains the gold standard for making the final diagnosis and determining the appropriate therapeutic procedure. This paper is a summary of the available knowledge on the symptoms, diagnosis and treatment options of cardiac tumors. Data were obtained from PubMed and Google Scholar.
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- 2023
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45. Intracardiac Metastases of Squamous Cell Carcinoma
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Vaideeswar, Pradeep, Kekatpure, Anuja, Yadav, Subhash, Lanke, Neha, and Vaideeswar, Pradeep, editor
- Published
- 2022
- Full Text
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46. Cardiac Posttransplant Lymphoproliferative Disorder
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Vaideeswar, Pradeep, Fernandes, Gwendolyn, Khairkar, Pritam, and Vaideeswar, Pradeep, editor
- Published
- 2022
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47. The Heart
- Author
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Kohli, Vinay Kumar, Kohli, Chitra, Singh, Akanksha, Kohli, Vinay Kumar, Kohli, Chitra, and Singh, Akanksha
- Published
- 2022
- Full Text
- View/download PDF
48. Primary intracardiac germ cell tumor.
- Author
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Chawla, Siddhi
- Subjects
WOUNDS & injuries ,EDEMA ,METASTASIS ,SCALP ,HEART tumors ,ECHOCARDIOGRAPHY ,GERM cell tumors - Abstract
We present the echocardiography images in a 6 year old girl who presented with a history of scalp swelling after trivial trauma which was subsequently diagnosed as metastases from primary intracardiac germ cell tumour. [ABSTRACT FROM AUTHOR]
- Published
- 2024
- Full Text
- View/download PDF
49. Atrial septal defect with a rare occupying lesion in heart
- Author
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Jinlan Chen, Xueyang Gong, Li Xie, Qin Wu, Tianli Zhao, and Shijun Hu
- Subjects
Cardiac tumors ,Cardiac epicardium hemangiomas ,Congenital heart disease ,Biopsy ,Infant ,Diseases of the circulatory (Cardiovascular) system ,RC666-701 - Abstract
Abstract Background Cardiac epicardium hemangiomas are exceedingly rare; however, they can cause significant hemodynamic impairment and large pericardial effusions. On rare occasion, cardiac tumors coexist with malformations of the heart. Case presentation We present the case of a 10-month-old female infant with a rare cardiac surface hemangioma coexisting with malformations of the heart. It revealed an atrial septal defect (ASD) coexisting with an abnormal occupying lesion with high echogenicity. It was 35*12*9 mm in size and was found in the anterior atrioventricular junction to the posterior atrioventricular junction at the bottom of the ventricular septum by transthoracic echocardiography. We performed surgical treatment of the atrial septal defect and performed biopsy with the occupying lesion. The histopathological examination reported a benign tumor as hemangioma. As far as we know, this is the first case in which cardiac surface hemangioma was found to coexist with an atrial septal defect. Conclusions Cardiac epicardium hemangiomas is a rare solid tumor of the heart. If the mass is impossible to resect and does not cause hemodynamic impairment, only mass biopsy is possible.
- Published
- 2022
- Full Text
- View/download PDF
50. TUMOR MASSES IN THREE OF THE FOUR HEART CHAMBERS
- Author
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Vladimir Kornovski, Andrey Andreev, Vera Semerdzhieva, Iana Simova, and Toni Vekov
- Subjects
cardiac masses ,heart chambers ,cardiac tumors ,thrombus formation ,Dentistry ,RK1-715 ,Medicine (General) ,R5-920 - Abstract
We present a case of a 47-year-old man who was admitted to the cardiac surgery department with a clinical picture of heart failure and multiple Tu-formations in three of the heart cavities. He underwent extraction of the tumor formations from the heart cavities with an excellent outcome.
- Published
- 2022
- Full Text
- View/download PDF
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