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1. Manejo de masas renales en receptores de trasplante renal. Revisión colaborativa de los grupos de trabajo de trasplante renal y cáncer renal de la sección de jóvenes urológos (YAU) de la Asociación Europea de Urología (EAU)

Author

Andras, I., Pecoraro, A., Telecan, T., Piana, A., Boissier, R., Hevia, V., Prudhomme, T., Amparore, D., Bertolo, R., Carbonara, U., Erdem, S., Diana, P., Ingels, A., Kara, O., Marandino, L., Marchioni, M., Muselaers, S., Pavan, N., Roussel, E., Crisan, N., Territo, A., and Campi, R.

Published
2023
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3. The comparison of prognostic models accuracy in non-metastatic papillary renal cell carcinoma undergoing curative surgical treatments: An analysis from international multi-institutional papillary renal cell carcinoma database

Author

Erdem, S., primary, Campi, R., additional, Klatte, T., additional, Capitanio, U., additional, Bertolo, R., additional, Roussel, E., additional, Amparore, D., additional, Pavan, N., additional, Wu, Z., additional, Mir, M.C., additional, Kara, O., additional, Carbonara, U., additional, Marchioni, M., additional, Anceschi, U., additional, Pazir, Y., additional, Muselaers, S., additional, Marandino, L., additional, Palumbo, C., additional, Warren, H., additional, Diana, P., additional, Simone, G., additional, Minervini, A., additional, Serni, S., additional, and Ozcan, F., additional

Published
2024
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4. Robotic-assisted nephrectomy in ADPKD: A single-center experience

Author

Labate, C., primary, Marzio, S., additional, Rella, L., additional, Vulpi, M., additional, Mizio, D., additional, Lippolis, G., additional, Filograsso, F.M., additional, Falsetti, F., additional, Gerbasi, S., additional, Lopinto, M., additional, Lospalluto, M., additional, Soldano, S., additional, Carbonara, U., additional, Forte, S., additional, Tedeschi, M., additional, Spilotros, M., additional, Lucarelli, G., additional, and Ditonno, P., additional

Published
2024
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5. Small renal masses in young adults: Insights from a large contemporary multi-institutional Registry

Author

Amparore, D., primary, Pecoraro, A., additional, Bertolo, R., additional, Marchioni, M., additional, Roussel, E., additional, Pavan, N., additional, Erdem, S., additional, Wu, Z., additional, Sharma, G., additional, Pandolfo, S.D., additional, Warren, H., additional, Caliò, A., additional, Carbonara, U., additional, Breda, A., additional, Simone, G., additional, Capitanio, U., additional, Minervini, A., additional, Campi, R., additional, and Palumbo, C., additional

Published
2024
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7. Learning curve in Robot-Assisted Kidney Transplantation (RAKT): A single centre experience

Author

Gerbasi, S., primary, Vulpi, M., additional, Magistro, R., additional, Matera, M., additional, Miacola, C., additional, Michele, T., additional, Palella, G., additional, Lospalluto, M., additional, Lopinto, M., additional, Filograsso, F.M., additional, Falsetti, F., additional, Soldano, S., additional, Mizio, D., additional, Rella, L., additional, Lippolis, G., additional, Marzio, S., additional, Forte, S., additional, Carbonara, U., additional, Spilotros, M., additional, Battaglia, M., additional, Lucarelli, G., additional, and Ditonno, P., additional

Published
2024
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9. Assessment of routine same-day discharge surgery for robot-assisted radical prostatectomy

Author

Broe, M., primary, Carbin Joseph, D.D., additional, Casson, H., additional, Innes, M., additional, Adamou, C., additional, Fragkoulis, G., additional, Carbonara, U., additional, Papadopoulos, D., additional, Moschonas, D., additional, Kusuma, V.R.M., additional, Hicks, J., additional, Patil, K., additional, Perry, M.J.A., additional, and Abou Chedid, W., additional

Published
2023
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14. Predictors of biochemical recurrence after robot-assisted radical prostatectomy: single-center analysis with a median follow-up period of 47 months

Author

Carbonara, U., primary, Adamou, C., additional, Fragkoulis, G., additional, Papadopoulos, D., additional, Darlington, D., additional, Whiting, D., additional, Kusuma, M., additional, Hicks, J., additional, Patil, K., additional, Moschonas, D., additional, Perry, M., additional, and Abou-Chedid, W., additional

Published
2023
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16. Screening programs for renal cell carcinoma: a systematic review by the EAU young academic urologists renal cancer working group

Author

Diana, P., Klatte, T., Amparore, D., Bertolo, R., Carbonara, U., Erdem, S., Ingels, A., Kara, O., Marandino, L., Marchioni, M., Muselaers, S., Pavan, N., Pecoraro, Angela, Pecoraro, Alessio, Roussel, E., Campi, R., Diana, P., Klatte, T., Amparore, D., Bertolo, R., Carbonara, U., Erdem, S., Ingels, A., Kara, O., Marandino, L., Marchioni, M., Muselaers, S., Pavan, N., Pecoraro, Angela, Pecoraro, Alessio, Roussel, E., and Campi, R.

Abstract

Item does not contain fulltext

Published
2023

17. Resection Techniques During Robotic Partial Nephrectomy: A Systematic Review.

Author

Bertolo, R., Pecoraro, A., Carbonara, U., Amparore, D., Diana, P., Muselaers, S., Marchioni, M., Mir, M.C., Antonelli, A., Badani, K., Breda, A van, Challacombe, B., Kaouk, J., Mottrie, A., Porpiglia, F., Porter, J., Minervini, A., Campi, R., Bertolo, R., Pecoraro, A., Carbonara, U., Amparore, D., Diana, P., Muselaers, S., Marchioni, M., Mir, M.C., Antonelli, A., Badani, K., Breda, A van, Challacombe, B., Kaouk, J., Mottrie, A., Porpiglia, F., Porter, J., Minervini, A., and Campi, R.

Abstract

01 juni 2023, Contains fulltext : 293046.pdf (Publisher’s version ) (Open Access), CONTEXT: The resection technique used to excise tumor during robotic partial nephrectomy (RPN) is of paramount importance in achieving optimal clinical outcomes. OBJECTIVE: To provide an overview of the different resection techniques used during RPN, and a pooled analysis of comparative studies. EVIDENCE ACQUISITION: The systematic review was conducted according to established principles (PROSPERO: CRD42022371640) on November 7, 2022. A population (P: adult patients undergoing RPN), intervention (I: enucleation), comparator (C: enucleoresection or wedge resection), outcome (O: outcome measurements of interest), and study design (S) framework was prespecified to assess study eligibility. Studies reporting a detailed description of resection techniques and/or evaluating the impact of resection technique on outcomes of surgery were included. EVIDENCE SYNTHESIS: Resection techniques used during RPN can be broadly classified as resection (non-anatomic) or enucleation (anatomic). A standardized definition for these is lacking. Out of 20 studies retrieved, nine compared "standard" resection versus enucleation. A pooled analysis did not reveal significant differences in terms of operative time, ischemia time, blood loss, transfusions, or positive margins. Significant differences favoring enucleation were found for clamping management (odds ratio [OR] for renal artery clamping 3.51, 95% confidence interval [CI] 1.13-10.88; p = 0.03), overall complications (OR for occurrence 0.55, 95% CI 0.34-0.87; p = 0.01) major complications (OR for occurrence 0.39, 95% CI 0.19-0.79; p = 0.009), length of stay (weighted mean difference [WMD] -0.72 d, 95% CI -0.99 to -0.45; p < 0.001), and decrease in estimated glomerular filtration rate (WMD -2.64 ml/min, 95% CI -5.15 to -0.12; p = 0.04). CONCLUSIONS: There is heterogeneity in the reporting of resection techniques used during RPN. The urological community must improve the quality of reporting and research produced accordingly. Positive mar

Published
2023

18. Single-port robotic partial nephrectomy: impact on perioperative outcomes and hospital stay.

Author

Carbonara, U., Amparore, D., Borregales, L.D., Caliò, A., Ciccarese, C., Diana, P., Erdem, S., Marandino, L., Marchioni, M., Muselaers, C.H.J., Palumbo, C., Pavan, N., Pecoraro, A., Roussel, E., Warren, H., Wu, Z.J., Campi, R., Bertolo, R., Carbonara, U., Amparore, D., Borregales, L.D., Caliò, A., Ciccarese, C., Diana, P., Erdem, S., Marandino, L., Marchioni, M., Muselaers, C.H.J., Palumbo, C., Pavan, N., Pecoraro, A., Roussel, E., Warren, H., Wu, Z.J., Campi, R., and Bertolo, R.

Abstract

Item does not contain fulltext, Single-port (SP) robotic surgery is a novel technology and is at the beginning of its adoption curve in urology. The goal of this narrative review is to provide an overview of SP-robotic partial nephrectomy (PN) 4 years after the introduction of the da Vinci SP dedicated platform, focusing on perioperative outcomes, length of stay, and surgical technique. A nonsystematic review of the literature was conducted. The research included the most updated articles that referred to SP robotic PN. Since its commercial release in 2018, several institutions have reproduced robotic PN by using the SP platform, both via a transperitoneal and a retroperitoneal approach. The published SP-robotic PN series are generally based on preliminary experiences by surgeons who had previous experience with conventional multi-arms robotic platforms. The reported outcomes are encouraging. Overall, three studies reported that SP-robotic PN cases had nonsignificantly different operative time, estimated blood loss, overall complications rate, and length of stay compared to the conventional 'multi-arms' robotic PN. However, in all these series, renal masses treated by SP had overall lower complexity. Moreover, two studies underlined decreased postoperative pain as a major pro of adopting the SP system. This should reduce/avoid the need for opioids after surgery. No study compared SP-robotic versus multi-arms robotic PN in cost-effectiveness. Published experience with SP-robotic PN has reported the feasibility and safety of the approach. Preliminary results are encouraging and at least noninferior with respect to those from the multi-arms series. Prospective comparative studies with long-term oncologic and functional results are awaited to draw more definitive conclusions and better establish the more appropriate indications of SP robotics in the field of PN.

Published
2023

19. Artificial Intelligence in Renal Cell Carcinoma Histopathology: Current Applications and Future Perspectives.

Author

Distante, A., Marandino, L., Bertolo, R., Ingels, A., Pavan, N., Pecoraro, A., Marchioni, M., Carbonara, U., Erdem, S., Amparore, D., Campi, R., Roussel, E., Caliò, A., Wu, Z., Palumbo, C., Borregales, L.D., Mulders, P.F.A., Muselaers, C.H.J., Distante, A., Marandino, L., Bertolo, R., Ingels, A., Pavan, N., Pecoraro, A., Marchioni, M., Carbonara, U., Erdem, S., Amparore, D., Campi, R., Roussel, E., Caliò, A., Wu, Z., Palumbo, C., Borregales, L.D., Mulders, P.F.A., and Muselaers, C.H.J.

Abstract

Contains fulltext : 294751.pdf (Publisher’s version ) (Open Access), Renal cell carcinoma (RCC) is characterized by its diverse histopathological features, which pose possible challenges to accurate diagnosis and prognosis. A comprehensive literature review was conducted to explore recent advancements in the field of artificial intelligence (AI) in RCC pathology. The aim of this paper is to assess whether these advancements hold promise in improving the precision, efficiency, and objectivity of histopathological analysis for RCC, while also reducing costs and interobserver variability and potentially alleviating the labor and time burden experienced by pathologists. The reviewed AI-powered approaches demonstrate effective identification and classification abilities regarding several histopathological features associated with RCC, facilitating accurate diagnosis, grading, and prognosis prediction and enabling precise and reliable assessments. Nevertheless, implementing AI in renal cell carcinoma generates challenges concerning standardization, generalizability, benchmarking performance, and integration of data into clinical workflows. Developing methodologies that enable pathologists to interpret AI decisions accurately is imperative. Moreover, establishing more robust and standardized validation workflows is crucial to instill confidence in AI-powered systems' outcomes. These efforts are vital for advancing current state-of-the-art practices and enhancing patient care in the future.

Published
2023

21. Robot-assisted partial nephrectomy versus percutaneous ablation for completely endophytic renal masses: a multicenter analysis with a minimum 3-year follow-up

Author

Pandolfo, S.D., primary, Beksac, A.T., additional, Loizzo, D., additional, Derweesh, I., additional, Cerrato, C., additional, Celia, A., additional, Schiavina, R., additional, Carbonara, U., additional, Crocerossa, F., additional, Capitanio, U., additional, Kim, F.J., additional, Aveta, A., additional, Barone, B., additional, Del Giudice, F., additional, Mirone, V., additional, Imbimbo, C., additional, and Autorino, R., additional

Published
2022
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22. Preoperative predictors of postoperative complications after robot-assisted and laparoscopic radical nephroureterectomy for upper tract urothelial carcinoma

Author

Crocerossa, F., primary, Carbonara, U., additional, Veccia, A., additional, Rosiello, G., additional, Tellini, R., additional, Mari, A., additional, Mastroianni, R., additional, Ferro, M., additional, De Cobelli, O., additional, Cacciamani, G., additional, Minervini, A., additional, Simone, G., additional, Cantiello, F., additional, Damiano, R., additional, and Autorino, R., additional

Published
2022
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23. On-clamp versus off-clamp robotic partial nephrectomy for totally endophytic “deep” renal masses: propensity score-matched comparison of perioperative, oncologic and functional outcomes of a multicenter analysis (rosula database)

Author

Tuderti, G., primary, Autorino, R., additional, Minervini, A., additional, Kaouk, J., additional, Lau, C., additional, Perdonà, S., additional, Porpiglia, F., additional, Derweesh, I., additional, Carbonara, U., additional, Rha, K.H., additional, Schiavina, R., additional, Mastroianni, R., additional, Misuraca, L., additional, Mari, A., additional, Brassetti, A., additional, Anceschi, U., additional, Bove, A., additional, Ferriero, M., additional, Mottrie, A., additional, Gallucci, M., additional, and Simone, G., additional

Published
2022
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24. Cryo- and radiofrequency versus microwave ablation for renal mass: multicenter comparative analysis

Author

Pandolfo, S.D., primary, Loizzo, D., additional, Beksac, A.T., additional, Derweesh, I., additional, Cerrato, C., additional, Celia, A., additional, Schiavina, R., additional, Carbonara, U., additional, Crocerossa, F., additional, Basile, G., additional, Kim, F.J., additional, La Rocca, R., additional, Aveta, A., additional, Del Giudice, F., additional, Mirone, V., additional, Imbimbo, C., additional, and Autorino, R., additional

Published
2022
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25. Changes in renal function after nephroureterectomy for upper urinary tract carcinoma: analysis of a large multicenter cohort (radical nephroureterectomy outcomes (RANEO) research consortium)

Author

Tafuri, A., primary, Marchioni, M., additional, Cerrato, C., additional, Mari, A., additional, Tellini, R., additional, Odorizzi, K., additional, Veccia, A., additional, Amparore, D., additional, Shakir, A., additional, Carbonara, U., additional, Trovato, F., additional, Catellani, M., additional, Janello, L.M.I., additional, Bianchi, L., additional, Novara, G., additional, Dal Moro, F., additional, Schiavina, R., additional, De Lorenzis, E., additional, Parma, P., additional, Cimino, S., additional, de Cobelli, O., additional, Maiorino, F., additional, Bove, P., additional, Crocerossa, F., additional, Cantiello, F., additional, D’andrea, D., additional, Di Cosmo, F., additional, Porpiglia, F., additional, Ditonno, P., additional, Montanari, E., additional, Soria, F., additional, Gontero, P., additional, Liguori, G., additional, Trombetta, C., additional, Mantica, G., additional, Borghesi, M., additional, Terrone, C., additional, Del Giudice, F., additional, Sciarra, A., additional, Galosi, A., additional, Moschini, M., additional, Shariat, S.F., additional, Di Nicola, M., additional, Minervini, A., additional, Ferro, M., additional, Cerruto, M.A., additional, Schips, L., additional, Pagliarulo, V., additional, and Antonelli, A., additional

Published
2022
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27. Expanding the Role of Ultrasound for the Characterization of Renal Masses

Author

Roussel, E., Campi, R., Amparore, D., Bertolo, R., Carbonara, U., Erdem, S., Ingels, A., Kara, Ö., Marandino, L., Marchioni, M., Muselaers, S., Pavan, N., Pecoraro, A., Beuselinck, B., Pedrosa, I., Fetzer, D., Albersen, M., Roussel, E., Campi, R., Amparore, D., Bertolo, R., Carbonara, U., Erdem, S., Ingels, A., Kara, Ö., Marandino, L., Marchioni, M., Muselaers, S., Pavan, N., Pecoraro, A., Beuselinck, B., Pedrosa, I., Fetzer, D., and Albersen, M.

Abstract

Item does not contain fulltext, The incidental detection of renal masses has been steadily rising. As a significant proportion of renal masses that are surgically treated are benign or indolent in nature, there is a clear need for better presurgical characterization of renal masses to minimize unnecessary harm. Ultrasound is a widely available and relatively inexpensive real-time imaging technique, and novel ultrasound-based applications can potentially aid in the non-invasive characterization of renal masses. Evidence acquisition: We performed a narrative review on novel ultrasound-based techniques that can aid in the non-invasive characterization of renal masses. Evidence synthesis: Contrast-enhanced ultrasound (CEUS) adds significant diagnostic value, particularly for cystic renal masses, by improving the characterization of fine septations and small nodules, with a sensitivity and specificity comparable to magnetic resonance imaging (MRI). Additionally, the performance of CEUS for the classification of benign versus malignant renal masses is comparable to that of computed tomography (CT) and MRI, although the imaging features of different tumor subtypes overlap significantly. Ultrasound molecular imaging with targeted contrast agents is being investigated in preclinical research as an addition to CEUS. Elastography for the assessment of tissue stiffness and micro-Doppler imaging for the improved detection of intratumoral blood flow without the need for contrast are both being investigated for the characterization of renal masses, though few studies have been conducted and validation is lacking. Conclusions: Several novel ultrasound-based techniques have been investigated for the non-invasive characterization of renal masses. CEUS has several advantages over traditional grayscale ultrasound, including the improved characterization of cystic renal masses and the potential to differentiate benign from malignant renal masses to some extent. Ultrasound molecular imaging offers promise for serial di

Published
2022

28. Finding novel prognostic factors in metastatic renal cell carcinoma: what does peripheral blood tell us?

Author

Marandino, L., Campi, R., Erdem, S., Bertolo, R., Marchioni, M., Ingels, A., Kara, Ö., Carbonara, U., Pecoraro, A., Pavan, N., Muselaers, S., Roussel, E., Amparore, D., Marandino, L., Campi, R., Erdem, S., Bertolo, R., Marchioni, M., Ingels, A., Kara, Ö., Carbonara, U., Pecoraro, A., Pavan, N., Muselaers, S., Roussel, E., and Amparore, D.

Abstract

Item does not contain fulltext

Published
2022

29. Potential benefit of lymph node dissection during radical nephrectomy for kidney cancer: A review and critical analysis of current literature

Author

Marchioni, M., Amparore, D., Magli, I.A., Bertolo, R., Carbonara, U., Erdem, S., Ingels, A., Muselaers, C.H.J., Kara, O., Mascitti, M., Klatte, T., Kriegmair, M., Pavan, N., Roussel, E., Pecoraro, A., Marandino, L., Campi, R., Schips, L., Marchioni, M., Amparore, D., Magli, I.A., Bertolo, R., Carbonara, U., Erdem, S., Ingels, A., Muselaers, C.H.J., Kara, O., Mascitti, M., Klatte, T., Kriegmair, M., Pavan, N., Roussel, E., Pecoraro, A., Marandino, L., Campi, R., and Schips, L.

Abstract

Contains fulltext : 282379.pdf (Publisher’s version ) (Open Access), OBJECTIVE: The role of lymph node dissection (LND) is still controversial in patients with renal cell carcinoma undergoing surgery. We aimed to provide a comprehensive review of the literature about the effect of LND on survival, prognosis, surgical outcomes, as well as patient selection and available LND templates. METHODS: Recent literature (from January 2011 to December 2021) was assessed through PubMed and MEDLINE databases. A narrative review of most relevant articles was provided. RESULTS: The frequencies in which LNDs are being carried out are decreasing due to an increase in minimally invasive and nephron sparing surgery. Moreover, randomized clinical trials and meta-analyses failed to show any survival advantage of LND versus no LND. However, retrospective studies suggest a survival benefit of LND in high-risk patients (bulky tumors, T3-4 stage, and cN1 patients). Moreover, extended LND might provide important staging information, which could be of interest for adjuvant treatment planning. CONCLUSION: No level 1 evidence of any survival advantage deriving from LND is currently available in literature. Thus, the role of LND is limited to staging purposes. However, low grade evidence suggests a possible role of LND in high-risk patients. Randomized clinical trials are warranted to corroborate these findings.

Published
2022

30. PSMA PET/CT in Renal Cell Carcinoma: An Overview of Current Literature

Author

Muselaers, S., Erdem, S., Bertolo, R., Ingels, A., Kara, Ö., Pavan, N., Roussel, E., Pecoraro, A., Marchioni, M., Carbonara, U., Marandino, L., Amparore, D., Campi, R., Muselaers, S., Erdem, S., Bertolo, R., Ingels, A., Kara, Ö., Pavan, N., Roussel, E., Pecoraro, A., Marchioni, M., Carbonara, U., Marandino, L., Amparore, D., and Campi, R.

Abstract

Contains fulltext : 251822.pdf (Publisher’s version ) (Open Access), Although the vast majority of prostate-specific membrane antigen (PSMA) positron emission tomography (PET) imaging occurs in the field of prostate cancer, PSMA is also highly expressed on the cell surface of the microvasculature of several other solid tumors, including renal cell carcinoma (RCC). This makes it a potentially interesting imaging target for the staging and monitoring of RCC. The objective of this review is to provide an overview of the current evidence regarding the use of PSMA PET/Computed Tomography in RCC patients.

Published
2022

31. Hot topics in renal cancer pathology: implications for clinical management

Author

Cimadamore, A., Caliò, A., Marandino, L., Marletta, S., Franzese, C., Schips, L., Amparore, D., Bertolo, R., Muselaers, S., Erdem, S., Ingels, A., Pavan, N., Pecoraro, A., Kara, Ö., Roussel, E., Carbonara, U., Campi, R., Marchioni, M., Cimadamore, A., Caliò, A., Marandino, L., Marletta, S., Franzese, C., Schips, L., Amparore, D., Bertolo, R., Muselaers, S., Erdem, S., Ingels, A., Pavan, N., Pecoraro, A., Kara, Ö., Roussel, E., Carbonara, U., Campi, R., and Marchioni, M.

Abstract

Item does not contain fulltext, INTRODUCTION: The updated European Association of Urology (EAU) Guidelines issued a weak recommendation for adjuvant pembrolizumab for patients with high-risk operable clear cell Renal Cell Carcinoma (ccRCC). High risk of recurrence was defined, as per protocol-criteria, as T2 with nuclear grade 4 or sarcomatoid differentiation, T3 or higher, regional lymph node metastasis, or stage M1 with no evidence of disease. Considering the heterogeneous population included in the recommendation, it has been questioned if adjuvant pembrolizumab may lead to overtreatment of some patients as well as undertreatment of patients with worse prognosis. AREAS COVERED: In this review, we discuss the issues related to the assessment of pathological features required to identify those patients harboring a high-risk tumor, highlighting the issue related to interobserver variability and discuss the currently available prognostic scoring systems in ccRCC. EXPERT OPINION: PPathologist assessment of prognostic features suffers from interobserver variability which may depend on gross sampling and the pathologist's expertise. The presence of clear cell feature is not sufficient criteria by itself to define ccRCC since clear cell can be also found in other histotypes. Application of molecular biomarkers may be useful tools in the near future to help clinicians identify patients harboring tumors with worse prognosis.

Published
2022

32. Renal surgery in elderly: not all partial nephrectomies should be treated equally

Author

Bertolo, R., Amparore, D., Erdem, S., Marchioni, M., Ingels, A., Kara, Ö., Carbonara, U., Pecoraro, A., Pavan, N., Marandino, L., Muselaers, S., Roussel, E., Campi, R., Bertolo, R., Amparore, D., Erdem, S., Marchioni, M., Ingels, A., Kara, Ö., Carbonara, U., Pecoraro, A., Pavan, N., Marandino, L., Muselaers, S., Roussel, E., and Campi, R.

Abstract

Item does not contain fulltext

Published
2022

33. Is Adjuvant Immunotherapy Worth for All Patients with Clear-cell Renal Cell Carcinoma at High Risk of Recurrence?

Author

Marchioni, M., Amparore, D., Marandino, L., Bertolo, R., Erdem, S., Ingels, A., Muselaers, S., Kara, O., Pavan, N., Roussel, E., Carbonara, U., Pecoraro, Angela, Diana, P., Pecoraro, Alessio, Campi, R., Marchioni, M., Amparore, D., Marandino, L., Bertolo, R., Erdem, S., Ingels, A., Muselaers, S., Kara, O., Pavan, N., Roussel, E., Carbonara, U., Pecoraro, Angela, Diana, P., Pecoraro, Alessio, and Campi, R.

Abstract

Item does not contain fulltext

Published
2022

35. Current strategies to diagnose and manage positive surgical margins and local recurrence after partial nephrectomy

Author

Carbonara, U., Amparore, D., Gentile, C., Bertolo, R., Erdem, S., Ingels, A., Marchioni, M., Muselaers, C.H.J., Kara, O., Marandino, L., Pavan, N., Roussel, E., Pecoraro, A., Crocerossa, F., Torre, G. de la, Campi, R., Ditonno, P., Carbonara, U., Amparore, D., Gentile, C., Bertolo, R., Erdem, S., Ingels, A., Marchioni, M., Muselaers, C.H.J., Kara, O., Marandino, L., Pavan, N., Roussel, E., Pecoraro, A., Crocerossa, F., Torre, G. de la, Campi, R., and Ditonno, P.

Abstract

Contains fulltext : 282351.pdf (Publisher’s version ) (Open Access), OBJECTIVE: No standard strategy for diagnosis and management of positive surgical margin (PSM) and local recurrence after partial nephrectomy (PN) are reported in literature. This review aims to provide an overview of the current strategies and further perspectives on this patient setting. METHODS: A non-systematic review of the literature was completed. The research included the most updated articles (about the last 10 years). RESULTS: Techniques for diagnosing PSMs during PN include intraoperative frozen section, imprinting cytology, and other specific tools. No clear evidence is reported about these methods. Regarding PSM management, active surveillance with a combination of imaging and laboratory evaluation is the first option line followed by surgery. Regarding local recurrence management, surgery is the primary curative approach when possible but it may be technically difficult due to anatomy resultant from previous PN. In this scenario, thermal ablation (TA) may have the potential to circumvent these limitations representing a less invasive alternative. Salvage surgery represents a valid option; six studies analyzed the outcomes of nephrectomy on local recurrence after PN with three of these focused on robotic approach. Overall, complication rates of salvage surgery are higher compared to TA but ablation presents a higher recurrence rate up to 25% of cases that can often be managed with repeat ablation. CONCLUSION: Controversy still exists surrounding the best strategy for management and diagnosis of patients with PSMs or local recurrence after PN. Active surveillance is likely to be the optimal first-line management option for most patients with PSMs. Ablation and salvage surgery both represent valid options in patients with local recurrence after PN. Conversely, salvage PN and radical nephrectomy have fewer recurrences but are associated with a higher complication rate compared to TA. In this scenario, robotic surgery plays an important role in improving sa

Published
2022

37. Nephrometry scores predicting value of Trifecta achievement in a multicenter analysis (ROSULA database) of Robotic Partial Nephrectomy for totally endophytic “deep” renal masses

Author

Tuderti, G., primary, Autorino, R., additional, Mastroianni, R., additional, Mari, A., additional, Carbonara, U., additional, Misuraca, L., additional, Anceschi, U., additional, Brassetti, A., additional, Ferriero, M., additional, Bove, A., additional, Costantini, M., additional, Porpiglia, F., additional, Kaouk, J., additional, Lau, C., additional, Derweesh, I., additional, Rha, K.H., additional, Schiavina, R., additional, Mottrie, A., additional, Gallucci, M., additional, and Simone, G., additional

Published
2022
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40. Impact of node count on survival outcomes of lymph node dissection in non-metastatic upper tract urothelial carcinoma: Analysis of the robuust registry

Author

Hakimi, K., primary, Carbonara, U., additional, Djaladat, H., additional, Mehrazin, R., additional, Eun, D., additional, Reese, A., additional, Gonzalgo, M., additional, Margulis, V., additional, Uzzo, R., additional, Porter, J., additional, Sundaram, C., additional, Abdollah, F., additional, Mottrie, A., additional, Tellini, R., additional, Ferro, M., additional, Meagher, M., additional, Saidian, A., additional, Walia, A., additional, Veccia, A., additional, Ghoriefi, A., additional, Cacciamani, G., additional, Bhattu, A., additional, Minervini, A., additional, Autorino, R., additional, and Derweesh, I., additional

Published
2022
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41. Oncological outcomes of patients who achieved surgical quality during minimally invasive radical nephroureterectomy for upper tract urothelial carcinoma: a multicenter retrospective analysis (ROBUUST collaborative group)

Author

Veccia, A., primary, Carbonara, U., additional, Tellini, R., additional, Meherazin, R., additional, Eun, D., additional, Margulis, V., additional, Uzzo, R., additional, Porter, J., additional, Sundaram, C., additional, Abdollah, F., additional, Mottrie, A., additional, Minervini, A., additional, Mari, A., additional, Rha, K., additional, Cacciamani, G., additional, Simone, G., additional, Ferro, M., additional, Wu, Z., additional, Djaladat, H., additional, Derweesh, I., additional, and Autorino, R., additional

Published
2021
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42. Surgical quality of robotic vs laparoscopic radical nephroureterectomy for upper tract urothelial carcinoma: a multicenter retrospective analysis (ROBUUST collaborative group)

Author

Veccia, A., primary, Carbonara, U., additional, Tellini, R., additional, Meherazin, R., additional, Eun, D., additional, Margulis, V., additional, Uzzo, R., additional, Porter, J., additional, Sundaram, C., additional, Abdollah, F., additional, Mottrie, A., additional, Minervini, A., additional, Mari, A., additional, Rha, K., additional, Cacciamani, G., additional, Simone, G., additional, Ferro, M., additional, Wu, Z., additional, Djaladat, H., additional, Derweesh, I., additional, and Autorino, R., additional

Published
2021
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44. Renal function deterioration assessment in totally endophytic “deep” renal masses treated with robotic partial nephrectomy: comparison with a whole cohort of cT1-2 renal tumors patients from a multicenter analysis (ROSULA database)

Author

Tuderti, G., primary, Autorino, R., additional, Carbonara, U., additional, Mari, A., additional, Amparore, D., additional, Mastroianni, R., additional, Bove, A.M., additional, Anceschi, U., additional, Perdonà, S., additional, Lau, C., additional, Koon, H.R., additional, Leonardo, C., additional, Misuraca, L., additional, Ferriero, M., additional, Brassetti, A., additional, Schiavina, R., additional, Derweesh, I., additional, Porpiglia, F., additional, Mottrie, A., additional, Kaouk, J., additional, Minervini, A., additional, and Simone, G., additional

Published
2021
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45. Robotic partial nephrectomy for totally endophytic “deep” renal masses: perioperative, pathologic, oncologic and functional outcomes of a multicenter analysis (ROSULA database)

Author

Misuraca, L., primary, Tuderti, G., additional, Autorino, R., additional, Carbonara, U., additional, Mari, A., additional, Amparore, D., additional, Mastroianni, R., additional, Bove, A.M., additional, Anceschi, U., additional, Ferriero, M., additional, Brassetti, A., additional, Perdonà, S., additional, Lau, C., additional, Koon, H.R., additional, Leonardo, C., additional, Schiavina, R., additional, Derweesh, I., additional, Porpiglia, F., additional, Mottrie, A., additional, Kaouk, J., additional, Minervini, A., additional, and Simone, G., additional

Published
2021
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46. Trifecta assessment in totally endophytic “deep” renal masses treated with robotic partial nephrectomy: comparison with a whole cohort of cT1-2 renal tumors patients from a multicenter analysis (ROSULA database)

Author

Tuderti, G., primary, Autorino, R., additional, Carbonara, U., additional, Mari, A., additional, Amparore, D., additional, Mastroianni, R., additional, Bove, A.M., additional, Anceschi, U., additional, Misuraca, L., additional, Ferriero, M., additional, Brassetti, A., additional, Perdonà, S., additional, Lau, C., additional, Koon, H.R., additional, Leonardo, C., additional, Schiavina, R., additional, Derweesh, I., additional, Porpiglia, F., additional, Mottrie, A., additional, Kaouk, J., additional, Minervini, A., additional, and Simone, G., additional

Published
2021
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49. Nephrometry scores predicting value of trifecta achievement in a multicenter analysis (ROSULA database) of robotic partial nephrectomy for totally endophytic “deep” renal masses

Author

Misuraca, L., primary, Tuderti, G., additional, Autorino, R., additional, Carbonara, U., additional, Mari, A., additional, Amparore, D., additional, Mastroianni, R., additional, Bove, A.M., additional, Anceschi, U., additional, Ferriero, M., additional, Brassetti, A., additional, Perdonà, S., additional, Lau, C., additional, Koon, H.R., additional, Leonardo, C., additional, Schiavina, R., additional, Derweesh, I., additional, Porpiglia, F., additional, Mottrie, A., additional, Kaouk, J., additional, Minervini, A., additional, and Simone, G., additional

Published
2021
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50. Predictors of complications after cytoreductive nephrectomy in the immunotherapy era: results from a multicenter international study

Author

Marchioni, M., primary, Rebez, G., additional, Campi, R., additional, Minervini, A., additional, Kriegmair, M., additional, Linares, E., additional, Hevia, V., additional, Veccia, A., additional, Carbonara, U., additional, Musquera, M., additional, D’Anna, M., additional, Darweesh, I., additional, Maegher, M., additional, Roussel, E., additional, Albersen, M., additional, Autorino, R., additional, Pavan, N., additional, Claps, F., additional, Antonelli, A., additional, Tafuri, A., additional, Erdem, S., additional, Paksoy, N., additional, and Mir, M.C., additional

Published
2021
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