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Your search keyword '"Caputo, Silvia"' showing total 19 results
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19 results on '"Caputo, Silvia"'

4. Nonvisualized sentinel node on preoperative lymphoscintigraphy in primary cutaneous melanoma: an 11-year retrospective survey

Author

Pallara, Tiziano, primary, Annovazzi, Alessio, additional, Cristiani, Renzo, additional, Vinci, Federica, additional, Bertozzi, Ettore, additional, Bonadies, Antonio, additional, Romani, Claudia, additional, Tedesco, Marinella, additional, Bellei, Barbara, additional, Papaccio, Federica, additional, Caputo, Silvia, additional, Cota, Carlo, additional, Sperduti, Isabella, additional, Govoni, Flavio Andrea, additional, Morrone, Aldo, additional, and Migliano, Emilia, additional

Published
2023
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5. Skin Cancer Microenvironment: What We Can Learn from Skin Aging?

Author

D'Arino, Andrea, Caputo, Silvia, Eibenschutz, Laura, Piemonte, Paolo, Buccini, Pierluigi, Frascione, Pasquale, and Bellei, Barbara

Subjects
*SKIN aging, *TUMOR microenvironment, *SKIN cancer, *CELLULAR aging, *ULTRAVIOLET radiation, *BIOLOGY
Abstract

Aging is a natural intrinsic process associated with the loss of fibrous tissue, a slower cell turnover, and a reduction in immune system competence. In the skin, the continuous exposition of environmental factors superimposes extrinsic damage, mainly due to ultraviolet radiation causing photoaging. Although not usually considered a pathogenic event, photoaging affects cutaneous biology, increasing the risk of skin carcinogenesis. At the cellular level, aging is typified by the rise of senescence cells a condition characterized by reduced or absent capacity to proliferate and aberrant hyper-secretory activity. Senescence has a double-edged sword in cancer biology given that senescence prevents the uncontrolled proliferation of damaged cells and favors their clearance by paracrine secretion. Nevertheless, the cumulative insults and the poor clearance of injured cells in the elderly increase cancer incidence. However, there are not conclusive data proving that aged skin represents a permissive milieu for tumor onset. On the other hand, tumor cells are capable of activating resident fibroblasts onto a pro-tumorigenic phenotype resembling those of senescent fibroblasts suggesting that aged fibroblasts might facilitate cancer progression. This review discusses changes that occur during aging that can prime neoplasm or increase the aggressiveness of melanoma and non-melanoma skin cancer. [ABSTRACT FROM AUTHOR]

Published
2023
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6. A Possible Modulator of Vitiligo Metabolic Impairment: Rethinking a PPARγ Agonist

Author

Papaccio, Federica, primary, Bellei, Barbara, additional, Ottaviani, Monica, additional, D’Arino, Andrea, additional, Truglio, Mauro, additional, Caputo, Silvia, additional, Cigliana, Giovanni, additional, Sciuto, Lorenzo, additional, Migliano, Emilia, additional, Pacifico, Alessia, additional, Iacovelli, Paolo, additional, and Picardo, Mauro, additional

Published
2022
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9. Evaluation of Hedgehog Pathway Inhibition on Nevoid Basal Cell Carcinoma Syndrome Fibroblasts and Basal Cell Carcinoma-Associated Fibroblasts: Are Vismodegib and Sonidegib Useful to Target Cancer-Prone Fibroblasts?

Author

Eibenschutz, Laura, primary, Caputo, Silvia, additional, Camera, Emanuela, additional, Carbone, Anna, additional, Silipo, Vitaliano, additional, Migliano, Emilia, additional, Aurizi, Caterina, additional, Cota, Carlo, additional, Frascione, Pasquale, additional, and Bellei, Barbara, additional

Published
2021
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13. Adipose tissue stromal vascular fraction and adipose tissue stromal vascular fraction plus platelet‐rich plasma grafting: New regenerative perspectives in genital lichen sclerosus

Author

Tedesco, Marinella, primary, Bellei, Barbara, additional, Garelli, Valentina, additional, Caputo, Silvia, additional, Latini, Alessandra, additional, Giuliani, Massimo, additional, Cota, Carlo, additional, Chichierchia, Giuseppina, additional, Romani, Claudia, additional, Foddai, Maria Laura, additional, Cristaudo, Antonio, additional, Morrone, Aldo, additional, and Migliano, Emilia, additional

Published
2020
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15. Additional file 1: of Adipose tissue-derived extracellular fraction characterization: biological and clinical considerations in regenerative medicine

Author

Bellei, Barbara, Migliano, Emilia, Tedesco, Marinella, Caputo, Silvia, Papaccio, Federica, Lopez, Gianluca, and Picardo, Mauro

Abstract

Figure S1. Cell proliferation of AT-Ex-treated cells. (a) NHF, (b) NHK, (c) NHM, and (d) ADSCs were harvested by incubation in 0.5% trypsin, 0.2% ethylenediaminetetraacetic acid (EDTA) at 37 °C. Cell viability was measured by Trypan blue exclusion assay. Histograms represent the number of viable cells after 72 h exposure to AT-Ex at different concentrations (1%, 2%, 5%, and 10% v/v in starved medium). Experiments were performed three times. Graphs represent the mean ± SD of three independent experiments; statistical significance versus untreated control is reported as *p

Published
2018
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