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1. Factors Affecting Patency of In Situ Saphenous Vein Bypass: Two Year Results from LIMBSAVE (Treatment of critical Limb Ischaemia with infragenicular Bypass adopting in situ SAphenous VEin technique) Registry

Author

Accrocca, Federico, Amico, Alessio, Angelini, Andrea, Arnuzzo, Luca, Marchetti, Andrea Ascoli, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chiama, Andrea, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco, Conti, Barbara, Coppi, Giovanni, De Blasis, Giovanni, D’Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Giordano, Antonio Nicola, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Salvini, Mauro, Scovazzi, Paolo, Setacci, Carlo, Settembrini, Alberto Maria, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Troisi, Nicola, Adami, Daniele, Michelagnoli, Stefano, and Berchiolli, Raffaella

Published
2022
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2. The Italian Multicentre Registry of Fenestrated Anaconda™ Endografts for Complex Abdominal Aortic Aneurysms Repair

Author

Pini, Rodolfo, Giordano, Jacopo, Ferri, Michelangelo, Palmieri, Bruno, Solcia, Marco, Michelagnoli, Stefano, Chisci, Emiliano, Fadda Gian, Franco, Cappiello, Pierluigi, Talarico, Francesco, Licata, Silvio, Frigatti, Paolo, Ronchey, Sonia, Mangialardi, Nicola, Pratesi, Carlo, Salvini, Mauro, Milite, Domenico, Pilon, Fabio, Perkmann, Reinhold, Stringari, Carlo, Pulli, Raffaele, Faggioli, Gianluca, and Gargiulo, Mauro

Published
2020
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4. Bypass vs endovascular treatment for occluded femoro-popliteal stents in patients with critical limb-threatening ischemia

Author

D’Oria, Mario, primary, Berchiolli, Raffaella, additional, Gargiulo, Mauro, additional, Antonello, Michele, additional, Pratesi, Giovanni, additional, Michelagnoli, Stefano, additional, Silingardi, Roberto, additional, Isernia, Giacomo, additional, Veraldi, Gian Franco, additional, Tinelli, Giovanni, additional, Giudice, Rocco, additional, Ippoliti, Arnaldo, additional, Cappiello, Pierluigi, additional, Martelli, Massimiliano, additional, Lepidi, Sandro, additional, Troisi, Nicola, additional, Abualhin, Mohammad, additional, Andreini, Marco, additional, Bastianon, Martina, additional, Calvagna, Cristiano, additional, Colacchio, Chiara, additional, D'Andrea, Alessia, additional, Esposito, Andrea, additional, Caneva, Patrizia Dalla, additional, Fazzini, Stefano, additional, Ferrer, Ciro, additional, Gallitto, Enrico, additional, Gennai, Stefano, additional, Giordano, Antonio Nicola, additional, Leone, Nicola, additional, Mastrorilli, Davide, additional, Melani, Caterina, additional, Mena Vera, Jorge Miguel, additional, Mezzetto, Luca, additional, Parlani, Gianbattista, additional, Scarati, Valentina, additional, Sica, Simona, additional, Simonte, Gioele, additional, Squizzato, Francesco, additional, Spath, Paolo, additional, Thsomba, Yamume, additional, Visciglia, Elvira, additional, and Zanetti, Elisa, additional

Published
2023
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5. Sex Related Differences and Factors Associated With Peri-Procedural and One Year Mortality in Chronic Limb Threatening Ischaemia Patients

Author

Martelli, Eugenio, Zamboni, Matilde, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe, Puci, Mariangela Valentina, Martelli, Allegra Rosa, Messina, Teresa, Frigatti, Paolo, Borrelli, Maria Pia, Ruotolo, Carlo, Ficarelli, Ilaria, Rubino, Paolo, Pezzo, Francesco, Carbonari, Luciano, Angelini, Andrea, Galeazzi, Edoardo, Calia di Pinto, Luca, Fiore, Franco Michelino, Palmieri, Armando, Ventoruzzo, Giorgio, Mazzitelli, Giulia, Ragni, Franco, Bozzani, Antonio, Forliti, Enzo, Castagno, Claudio, Volpe, Pietro, Massaro, Mafalda, Moniaci, Diego, Pagliasso, Elisa, Peretti, Tania, Ferrari, Mauro, Troisi, Nicola, Modugno, Piero, Maiorano, Maurizio, Bracale, Umberto Marcello, Panagrosso, Marco, Monaco, Mario, Giordano, Giovanni, Natalicchio, Giuseppe, Biello, Antonella, Celoria, Giovanni Maria, Amico, Alessio, Di Bartolo, Mauro, Martelli, Massimiliano, Munaò, Roberta, Razzano, Davide, Colacchio, Giovanni, Bussetti, Francesco, Lanza, Gaetano, Cardini, Antonio, Di Benedetto, Bartolomeo, De Laurentis, Mario, Taurino, Maurizio, Sirignano, Pasqualino, Cappiello, Pierluigi, Esposito, Andrea, Trimarchi, Santi, Romagnoli, Silvia, Padricelli, Andrea, Giudice, Giorgio, Crinisio, Adolfo, Di Nardo, Giovanni, Battaglia, Giuseppe, Tringale, Rosario, De Vivo, Salvatore, Compagna, Rita, Tolva, Valerio Stefano, D'Alessio, Ilenia, Curci, Ruggiero, Giovannetti, Simona, D'Arrigo, Giuseppe, Basile, Giusi, Frigerio, Dalmazio, Veraldi, Gianfranco, Mezzetto, Luca, Ippoliti, Arnaldo, Oddi, Fabio Massimo, and Settembrini, Alberto Maria

Published
2024
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6. Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Martelli, Eugenio, primary, Zamboni, Matilde, additional, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe M., additional, Puci, Mariangela V., additional, Martelli, Allegra R., additional, Messina, Teresa, additional, Frigatti, Paolo, additional, Borrelli, Maria Pia, additional, Ruotolo, Carlo, additional, Ficarelli, Ilaria, additional, Rubino, Paolo, additional, Pezzo, Francesco, additional, Carbonari, Luciano, additional, Angelini, Andrea, additional, Galeazzi, Edoardo, additional, Di Pinto, Luca Calia, additional, Fiore, Franco M., additional, Palmieri, Armando, additional, Ventoruzzo, Giorgio, additional, Mazzitelli, Giulia, additional, Ragni, Franco, additional, Bozzani, Antonio, additional, Forliti, Enzo, additional, Castagno, Claudio, additional, Volpe, Pietro, additional, Massara, Mafalda, additional, Moniaci, Diego, additional, Pagliasso, Elisa, additional, Peretti, Tania, additional, Ferrari, Mauro, additional, Troisi, Nicola, additional, Modugno, Piero, additional, Maiorano, Maurizio, additional, Bracale, Umberto M., additional, Panagrosso, Marco, additional, Monaco, Mario, additional, Giordano, Giovanni, additional, Natalicchio, Giuseppe, additional, Biello, Antonella, additional, Celoria, Giovanni M., additional, Amico, Alessio, additional, Di Bartolo, Mauro, additional, Martelli, Massimiliano, additional, Munaó, Roberta, additional, Razzano, Davide, additional, Colacchio, Giovanni, additional, Bussetti, Francesco, additional, Lanza, Gaetano, additional, Cardini, Antonio, additional, Di Benedetto, Bartolomeo, additional, De Laurentis, Mario, additional, Taurino, Maurizio, additional, Sirignano, Pasqualino, additional, Cappiello, Pierluigi, additional, Esposito, Andrea, additional, Trimarchi, Santi, additional, Romagnoli, Silvia, additional, Padricelli, Andrea, additional, Giudice, Giorgio, additional, Crinisio, Adolfo, additional, Di Nardo, Giovanni, additional, Battaglia, Giuseppe, additional, Tringale, Rosario, additional, De Vivo, Salvatore, additional, Compagna, Rita, additional, Tolva, Valerio S., additional, D’Alessio, Ilenia, additional, Curci, Ruggiero, additional, Giovannetti, Simona, additional, D’Arrigo, Giuseppe, additional, Basile, Giusi, additional, Frigerio, Dalmazio, additional, Veraldi, Gian Franco, additional, Mezzetto, Luca, additional, Ippoliti, Arnaldo, additional, Oddi, Fabio M., additional, and Settembrini, Alberto M., additional

Published
2023
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7. Sex-Related Differences and Factors Associated with Peri-Procedural and 1-year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Martelli, Eugenio, primary, Zamboni, Matilde, additional, Sotgiu, Giovanni, additional, Saderi, Laura, additional, Federici, Massimo, additional, Sangiorgi, Giuseppe Massimo, additional, Puci, Mariangela Valentina, additional, Martelli, Allegra Rosa, additional, Messina, Teresa, additional, Frigatti, Paolo, additional, Borrelli, Maria Pia, additional, Ruotolo, Carlo, additional, Ficarelli, Ilaria, additional, Rubino, Paolo, additional, Pezzo, Francesco, additional, Carbonari, Luciano, additional, Angelini, Andrea, additional, Galeazzi, Edoardo, additional, Di Pinto, Luca Calia, additional, Fiore, Franco Michelino, additional, Palmieri, Armado, additional, Ventoruzzo, Giorgio, additional, Mazzitelli, Giulia, additional, Ragni, Franco, additional, Bozzani, Antonio, additional, Forliti, Enzo, additional, Castagno, Claudio, additional, Volpe, Pietro, additional, Massara, Mafalda, additional, Moniaci, Diego, additional, Pagliasso, Elisa, additional, Peretti, Tania, additional, Ferrari, Mauro, additional, Troisi, Nicola, additional, Modugno, Pietro, additional, Maiorano, Maurizio, additional, Bracale, Umberto Marcello, additional, Panagrosso, Marco, additional, Monaco, Mario, additional, Giordano, Giovanni, additional, Natalicchio, Giuseppe, additional, Biello, Antonella, additional, Celoria, Giovanni Maria, additional, Amico, Alessio, additional, Di Bartolo, Mauro, additional, Martelli, Massimiliano, additional, Munaó, Roberta, additional, Razzano, Davide, additional, Colacchio, Giovanni, additional, Bussetti, Francesco, additional, Lanza, Gaetano, additional, Cardini, Antonio, additional, Di Benedetto, Bartolomeo, additional, De Laurentis, Mario, additional, Taurino, Maurizio, additional, Sirignano, Pasqualino, additional, Cappiello, Pierluigi, additional, Esposito, Andrea, additional, Trimarchi, Santi, additional, Romagnoli, Silvia, additional, Padricelli, Andrea, additional, Giudice, Giorgio, additional, Crinisio, Adolfo, additional, Di Nardo, Giovanni, additional, Battaglia, Giuseppe, additional, Tringale, Rosario, additional, De Vivo, Salvatore, additional, Compagna, Rita, additional, Tolva, Valerio Stefano, additional, D'Alessio, Ilenia, additional, Curci, Ruggiero, additional, Giovannetti, Simona, additional, D'Arrigo, Giuseppe, additional, Basile, Giusi, additional, Frigerio, Dalmazio, additional, Veraldi, Gian Franco, additional, Mezzetto, Luca, additional, Ippoliti, Arnaldo, additional, Oddi, Fabio Massimo, additional, and Settembrini, Alberto Maria, additional

Published
2022
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8. Bypass vs endovascular treatment for occluded femoro-popliteal stents in patients with critical limb-threatening ischemia.

Author

D'Oria, Mario, Berchiolli, Raffaella, Gargiulo, Mauro, Antonello, Michele, Pratesi, Giovanni, Michelagnoli, Stefano, Silingardi, Roberto, Isernia, Giacomo, Veraldi, Gian Franco, Tinelli, Giovanni, Giudice, Rocco, Ippoliti, Arnaldo, Cappiello, Pierluigi, Martelli, Massimiliano, Lepidi, Sandro, and Troisi, Nicola

Abstract

The aim of the study was to compare the early and medium-term outcomes of bypass vs endovascular treatment of occluded femoro-popliteal stents in patients with chronic limb-threatening ischemia (the OUT-STEPP multicentric registry). Between January 2016 and December 2021, 317 patients in 14 centers underwent treatment for a symptomatic occlusion of femoro-popliteal stent/stents. One hundred sixty-one patients were included into the present study: 46 (28.6%) underwent open bypass surgery (Group OPEN), and 115 (71.4%) underwent endovascular revascularization (Group ENDO). Early (30 days) results were assessed and compared between the two groups. Estimated 5-year outcomes were evaluated and compared with the log rank test. At 30 days, no differences were found in terms of major adverse cardiovascular events, acute kidney injury, reinterventions, major amputation, and all-cause mortality between the two groups. The need for blood transfusions was higher for patients in Group OPEN (17; 36.9% vs 13; 11.3%; P <.001). The mean length of intensive care unit stay and the mean hospital stay were higher for patients in Group OPEN ([0.3 ± 0.9 vs 0 days; P <.001] and [9.7 ± 5.8 vs 3.3 ± 1.4 days; P <.001], respectively). The overall median duration of follow-up was 33.1 months (interquartile range, 14-49.5 months). At 5 years, there were no differences between the two groups in terms of survival (68.7% Group OPEN vs 68.8% Group ENDO; P =.27; log-rank, 1.21), primary patency (56.3% Group OPEN vs 67.8% Group ENDO; P =.39; log-rank, 0.75), secondary patency (59.1% Group OPEN vs 77.8% Group ENDO; P =.24; log-rank, 1.40), absence of target lesion restenosis (56.8% Group OPEN vs 62.7% Group ENDO; P =.42; log-rank, 0.65), and limb salvage (77.2% Group OPEN vs 90.4% Group ENDO; P =.17; log-rank, 1.87). Both bypass and endovascular treatment provided safe and effective restoration of patency for femoro-popliteal in-stent occlusion in patients with chronic limb-threatening ischemia. Open surgery was associated with longer stay in hospital and increased use of blood transfusions. At 5 years, no significant differences were found in the rates of overall patency or limb salvage between bypass and endovascular treatment. [ABSTRACT FROM AUTHOR]

Published
2023
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9. Factors Affecting Patency of In Situ Saphenous Vein Bypass: Two Year Results from LIMBSAVE (Treatment of critical Limb Ischaemia with infragenicular Bypass adopting in situ SAphenous VEin technique) Registry

Author

Troisi, Nicola, primary, Adami, Daniele, additional, Michelagnoli, Stefano, additional, Berchiolli, Raffaella, additional, Accrocca, Federico, additional, Amico, Alessio, additional, Angelini, Andrea, additional, Arnuzzo, Luca, additional, Marchetti, Andrea Ascoli, additional, Attisani, Luca, additional, Bafile, Gennaro, additional, Baldino, Giuseppe, additional, Barbanti, Enrico, additional, Bartoli, Stefano, additional, Bellosta, Raffaello, additional, Benedetto, Filippo, additional, Borioni, Raoul, additional, Briolini, Franco, additional, Busoni, Cristina, additional, Camparini, Stefano, additional, Cappiello, Pierluigi, additional, Carbonari, Luciano, additional, Casella, Francesco, additional, Celoria, Giovanni, additional, Chiama, Andrea, additional, Chisci, Emiliano, additional, Civilini, Efrem, additional, Codispoti, Francesco, additional, Conti, Barbara, additional, Coppi, Giovanni, additional, De Blasis, Giovanni, additional, D’Elia, Marcello, additional, Di Domenico, Rossella, additional, Di Girolamo, Carla, additional, Ercolini, Leonardo, additional, Ferrari, Alessandra, additional, Ferrari, Mauro, additional, Forliti, Enzo, additional, Frigatti, Paolo, additional, Frigerio, Dalmazio, additional, Frosini, Pierfrancesco, additional, Garriboli, Luca, additional, Giordano, Antonio Nicola, additional, Guerrieri, Walter, additional, Jannello, Antonio, additional, Massara, Mafalda, additional, Merlo, Maurizio, additional, Mezzetti, Roberto, additional, Miccoli, Tommaso, additional, Milite, Domenico, additional, Mingazzini, Pietro, additional, Muncinelli, Marina, additional, Nano, Giovanni, additional, Natola, Marco, additional, Novali, Claudio, additional, Palasciano, Giancarlo, additional, Perkmann, Reinhold, additional, Persi, Federica, additional, Petruccelli, David, additional, Pinelli, Mauro, additional, Poletto, Giorgio, additional, Porta, Carla, additional, Pratesi, Carlo, additional, Pruner, Gianguido, additional, Ragazzi, Giovanni, additional, Righini, Paolo, additional, Salvini, Mauro, additional, Scovazzi, Paolo, additional, Setacci, Carlo, additional, Settembrini, Alberto Maria, additional, Siani, Andrea, additional, Silingardi, Roberto, additional, Silvestro, Antonino, additional, Talarico, Francesco, additional, Tolva, Valerio, additional, Trani, Antonio, additional, Trimarchi, Santi, additional, Tshomba, Yamume, additional, Vigliotti, Gennaro, additional, Viola, Daniela, additional, Volpe, Pietro, additional, and Zani, Federico, additional

Published
2022
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10. Comparison of long occlusive femoropopliteal de novo versus previous endovascularly treated lesions managed with in situ saphenous bypass

Author

Troisi, Nicola, primary, Michelagnoli, Stefano, additional, Adami, Daniele, additional, Berchiolli, Raffaella, additional, Accrocca, Federico, additional, Amico, Alessio, additional, Angelini, Andrea, additional, Arnuzzo, Luca, additional, Marchetti, Andrea Ascoli, additional, Attisani, Luca, additional, Bafile, Gennaro, additional, Baldino, Giuseppe, additional, Barbanti, Enrico, additional, Bartoli, Stefano, additional, Bellosta, Raffaello, additional, Benedetto, Filippo, additional, Borioni, Raoul, additional, Briolini, Franco, additional, Busoni, Cristina, additional, Camparini, Stefano, additional, Cappiello, Pierluigi, additional, Carbonari, Luciano, additional, Casella, Francesco, additional, Celoria, Giovanni, additional, Chiama, Andrea, additional, Chisci, Emiliano, additional, Civilini, Efrem, additional, Codispoti, Francesco, additional, Conti, Barbara, additional, Coppi, Giovanni, additional, De Blasis, Giovanni, additional, D’Elia, Marcello, additional, Di Domenico, Rossella, additional, Di Girolamo, Carla, additional, Ercolini, Leonardo, additional, Ferrari, Alessandra, additional, Ferrari, Mauro, additional, Forliti, Enzo, additional, Frigatti, Paolo, additional, Frigerio, Dalmazio, additional, Frosini, Pierfrancesco, additional, Garriboli, Luca, additional, Giordano, Antonio Nicola, additional, Guerrieri, Walter, additional, Jannello, Antonio, additional, Massara, Mafalda, additional, Merlo, Maurizio, additional, Mezzetti, Roberto, additional, Miccoli, Tommaso, additional, Milite, Domenico, additional, Mingazzini, Pietro, additional, Muncinelli, Marina, additional, Nano, Giovanni, additional, Natola, Marco, additional, Novali, Claudio, additional, Palasciano, Giancarlo, additional, Perkmann, Reinhold, additional, Persi, Federica, additional, Petruccelli, David, additional, Pinelli, Mauro, additional, Poletto, Giorgio, additional, Porta, Carla, additional, Pratesi, Carlo, additional, Pruner, Gianguido, additional, Ragazzi, Giovanni, additional, Righini, Paolo, additional, Salvini, Mauro, additional, Scovazzi, Paolo, additional, Setacci, Carlo, additional, Settembrini, Alberto Maria, additional, Siani, Andrea, additional, Silingardi, Roberto, additional, Silvestro, Antonino, additional, Talarico, Francesco, additional, Tolva, Valerio, additional, Trani, Antonio, additional, Trimarchi, Santi, additional, Tshomba, Yamume, additional, Vigliotti, Gennaro, additional, Viola, Daniela, additional, Volpe, Pietro, additional, and Zani, Federico, additional

Published
2022
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11. Comparison of long occlusive femoropopliteal de novo versus previous endovascularly treated lesions managed with in situ saphenous bypass

Author

Troisi, Nicola, Michelagnoli, Stefano, Adami, Daniele, Berchiolli, Raffaella, Accrocca, Federico, Amico, Alessio, Angelini, Andrea, Arnuzzo, Luca, Marchetti, Andrea Ascoli, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chiama, Andrea, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, De Blasis, Giovanni, D'Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Giordano, Antonio Nicola, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Salvini, Mauro, Scovazzi, Paolo, Setacci, Carlo, Settembrini, Alberto Maria, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, Tshomba, Yamume (ORCID:0000-0001-7304-7553), Troisi, Nicola, Michelagnoli, Stefano, Adami, Daniele, Berchiolli, Raffaella, Accrocca, Federico, Amico, Alessio, Angelini, Andrea, Arnuzzo, Luca, Marchetti, Andrea Ascoli, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chiama, Andrea, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, De Blasis, Giovanni, D'Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Giordano, Antonio Nicola, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Salvini, Mauro, Scovazzi, Paolo, Setacci, Carlo, Settembrini, Alberto Maria, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, and Tshomba, Yamume (ORCID:0000-0001-7304-7553)

Abstract

Background: The aim of this study was to compare the 2-year outcomes of de novo versus postendovascular lesion treatment of femoropopliteal occlusions included in a national, multicenter, observational, prospective registry based on the treatment of critical Limb-threatening IschaeMia with infragenicular Bypass adopting in situ SAphenous VEin technique (LIMBSAVE) registry.Methods: From January 2018 to December 2019, 541 patients from43 centers have been enrolled in the LIMBSAVE registry. Of these patients, 460 were included in the present study: 341 (74.1%) with de novo lesions (DN group) and 119 (25.9%) with postendovascular treatment lesions (PE group). Initial outcome measures were assessed at 30 days after treatment. Furthermore, at the 2-year follow-up, the estimated outcomes of primary patency, primary-assisted patency, secondary patency, and limb salvage were analyzed with Kaplan-Meier curves and compared between groups with the log-rank test.Results: Both groups were homogeneous in terms of demographic data, preoperative risk factors, and clinical presentation. However, compared with DN group, more patients in PE group had a great saphenous vein diameter of less than 3 mm (11.1% vs 21%; P = .007). Intraoperatively, both groups showed similar distal anastomosis sites: below-the-knee popliteal artery (63% DN group, 66.4% PE group) and tibial vessel (37% DN group, 33.6% PE group) (P = .3). The overall mean duration of follow-up was 11.6 months (range, 1-24 months). At the 2-year follow-up, there were no differences between the two groups in terms of primary patency (66.3% DN group vs 74.1% PE group; P = .9), primary-assisted patency (78.2% DN group vs 79.5% PE group; P = .2), secondary patency (85.1% DN group vs 91.4% PE group; P = .2), and limb salvage (95.2% DN group vs 95.1% PE group; P = .9).Conclusions: The LIMBSAVE registry did not show a worsening of overall patency and limb salvages rates at the 2-year follow-up in patients undergoing in situ saphenous

Published
2022

13. Preliminary six-month outcomes of LIMBSAVE (treatment of critical Limb IscheMia with infragenicular Bypass adopting in situ SAphenous VEin technique) registry

Author

Troisi, Nicola, Blasis, Giovanni De, Salvini, Mauro, Michelagnoli, Stefano, Setacci, Carlo, LIMBSAVE registry Collaborative, Group, Accrocca, Federico, Adami, Daniele, Angelini, Andrea, Arnuzzo, Luca, Ascoli Marchetti, Andrea, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, D’Amico, Alessio, De Blasis, Giovanni, D’Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Nicola Giordano, Antonio, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Scovazzi, Paolo, Maria Settembrini, Alberto, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, Tshomba, Yamume (ORCID:0000-0001-7304-7553), Troisi, Nicola, Blasis, Giovanni De, Salvini, Mauro, Michelagnoli, Stefano, Setacci, Carlo, LIMBSAVE registry Collaborative, Group, Accrocca, Federico, Adami, Daniele, Angelini, Andrea, Arnuzzo, Luca, Ascoli Marchetti, Andrea, Attisani, Luca, Bafile, Gennaro, Baldino, Giuseppe, Barbanti, Enrico, Bartoli, Stefano, Bellosta, Raffaello, Benedetto, Filippo, Borioni, Raoul, Briolini, Franco, Busoni, Cristina, Camparini, Stefano, Cappiello, Pierluigi, Carbonari, Luciano, Casella, Francesco, Celoria, Giovanni, Chisci, Emiliano, Civilini, Efrem, Codispoti, Francesco Alberto, Conti, Barbara, Coppi, Giovanni, D’Amico, Alessio, De Blasis, Giovanni, D’Elia, Marcello, Di Domenico, Rossella, Di Girolamo, Carla, Ercolini, Leonardo, Ferrari, Alessandra, Ferrari, Mauro, Forliti, Enzo, Frigatti, Paolo, Frigerio, Dalmazio, Frosini, Pierfrancesco, Garriboli, Luca, Nicola Giordano, Antonio, Guerrieri, Walter, Jannello, Antonio, Massara, Mafalda, Merlo, Maurizio, Mezzetti, Roberto, Miccoli, Tommaso, Milite, Domenico, Mingazzini, Pietro, Muncinelli, Marina, Nano, Giovanni, Natola, Marco, Novali, Claudio, Palasciano, Giancarlo, Perkmann, Reinhold, Persi, Federica, Petruccelli, David, Pinelli, Mauro, Poletto, Giorgio, Porta, Carla, Pratesi, Carlo, Pruner, Gianguido, Ragazzi, Giovanni, Righini, Paolo, Scovazzi, Paolo, Maria Settembrini, Alberto, Siani, Andrea, Silingardi, Roberto, Silvestro, Antonino, Talarico, Francesco, Tolva, Valerio, Trani, Antonio, Trimarchi, Santi, Tshomba, Yamume, Vigliotti, Gennaro, Viola, Daniela, Volpe, Pietro, Zani, Federico, Codispoti, Francesco, and Tshomba, Yamume (ORCID:0000-0001-7304-7553)

Abstract

ObjectivesGuidelines recommend open bypass surgery for long occlusions of infrainguinal arteries. In situ saphenous vein bypass is a standardized technique. The aim of this study was to report preliminary six-month outcomes of a national, multicenter, observational, prospective registry based on the examination of treatment of critical Limb IscheMia with infragenicular Bypass adopting the in situ SAphenous VEin technique (LIMBSAVE).MethodsFrom January 2018 until October 2019, 428 patients from 41 centers were enrolled in the LIMBSAVE registry. Data were prospectively collected in a dedicated database, including demographics, preoperative risk factors, clinical and diagnostic preoperative assessments, intraoperative measures (including safety and effectiveness of the valvulotome during the surgical procedures), and 30-day follow-up data. Furthermore, estimated six-month outcomes according to Kaplan-Meier curves in terms of primary patency, primary assisted patency, secondary patency, and limb salvage were evaluated.ResultsPatients were predominantly male (n = 332, 77.6%) with a mean age of 73.3 years (range 39-95). Technical success, defined as bypass pulse after use of the valvulotome, was obtained in all cases. The proximal anastomosis could be reached by the valvulotome in all cases. The mean number of valvulotome uses was 2.5 (range 1-5). No vein perforation was reported. In nine cases (2.1%), a vein lesion with intramural hemorrhage occurred. The mean length of hospital stay was 11.1 days (range 1-60). At 30-day follow-up, the overall bypass patency rate was 97.4%, and the rate of open or endo reinterventions for failing bypass was 5.4%. At six-month follow-up, the estimated primary patency, primary assisted patency, secondary patency, and limb salvage were 78.1%, 86.2%, 92.1%, and 94.7%, respectively.ConclusionsPreliminary intraprocedural outcomes of the LIMBSAVE registry show that the in situ technique with the valvulotome is safe and effective in disrupting v

Published
2021

17. Pharmacological therapy in critically ill patients with peripheral and concomitant arteriopathy: Terapia farmacologica nel paziente critico con arteriopatia periferica e concomitante

Author

Troisi, Nicola, Trani, Antonio, Cappiello, Pierluigi Antonino, Troisi, Nicola, Trani, Antonio, and Cappiello, Pierluigi Antonino

Abstract

Peripheral arterial disease is one of the most frequent clinical manifestations of atherosclerotic disease. The clinical picture of critical ischemia of the lower limbs is often burdened by high mortality and the risk of limb amputation. The direct and indirect prostanoids, and in particular iloprost and cilostazol, are effective in the medical treatment of peripheral arterial disease. We describe here five clinical cases in which iloprost and cilostazol have been successfully administered in arterial patients with various concomitant cardiovascular diseases, highlighting a good safety profile in relation to the cardiocascular risk profile (Cardiology).

Published
2018

18. Lower cardiovascular mortality with Medtronic CoreValve versus Edwards SAPIEN in patients with aortic valve stenosis undergoing transcatheter aortic valve implantation

Author

Tarsia, Giandomenico, Smaldone, Costantino, Viceconte, Nicola G., Osanna, Rocco A., Santillo, Vincenza, Cuda, Cristiano, Polosa, Domenico, Costantino, Marco F., Del Prete, Giuseppe, Pittella, Giuseppe, Scarano, Enrico, Cappiello, Pierluigi, Di Natale, Maurilio, Sisto, Francesco, Marraudino, Nicola, and Lisanti, Pasquale

Published
2014
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20. Sex-Related Differences and Factors Associated with Peri-Procedural and 1 Year Mortality in Chronic Limb-Threatening Ischemia Patients from the CLIMATE Italian Registry

Author

Eugenio Martelli, Matilde Zamboni, Giovanni Sotgiu, Laura Saderi, Massimo Federici, Giuseppe M. Sangiorgi, Mariangela V. Puci, Allegra R. Martelli, Teresa Messina, Paolo Frigatti, Maria Pia Borrelli, Carlo Ruotolo, Ilaria Ficarelli, Paolo Rubino, Francesco Pezzo, Luciano Carbonari, Andrea Angelini, Edoardo Galeazzi, Luca Calia Di Pinto, Franco M. Fiore, Armando Palmieri, Giorgio Ventoruzzo, Giulia Mazzitelli, Franco Ragni, Antonio Bozzani, Enzo Forliti, Claudio Castagno, Pietro Volpe, Mafalda Massara, Diego Moniaci, Elisa Pagliasso, Tania Peretti, Mauro Ferrari, Nicola Troisi, Piero Modugno, Maurizio Maiorano, Umberto M. Bracale, Marco Panagrosso, Mario Monaco, Giovanni Giordano, Giuseppe Natalicchio, Antonella Biello, Giovanni M. Celoria, Alessio Amico, Mauro Di Bartolo, Massimiliano Martelli, Roberta Munaó, Davide Razzano, Giovanni Colacchio, Francesco Bussetti, Gaetano Lanza, Antonio Cardini, Bartolomeo Di Benedetto, Mario De Laurentis, Maurizio Taurino, Pasqualino Sirignano, Pierluigi Cappiello, Andrea Esposito, Santi Trimarchi, Silvia Romagnoli, Andrea Padricelli, Giorgio Giudice, Adolfo Crinisio, Giovanni Di Nardo, Giuseppe Battaglia, Rosario Tringale, Salvatore De Vivo, Rita Compagna, Valerio S. Tolva, Ilenia D’Alessio, Ruggiero Curci, Simona Giovannetti, Giuseppe D’Arrigo, Giusi Basile, Dalmazio Frigerio, Gian Franco Veraldi, Luca Mezzetto, Arnaldo Ippoliti, Fabio M. Oddi, Alberto M. Settembrini, Martelli, Eugenio, Zamboni, Matilde, Sotgiu, Giovanni, Saderi, Laura, Federici, Massimo, Sangiorgi, Giuseppe M., Puci, Mariangela V., Martelli, Allegra R., Messina, Teresa, Frigatti, Paolo, Borrelli, Maria Pia, Ruotolo, Carlo, Ficarelli, Ilaria, Rubino, Paolo, Pezzo, Francesco, Carbonari, Luciano, Angelini, Andrea, Galeazzi, Edoardo, Di Pinto, Luca Calia Di, Fiore, Franco M., Palmieri, Armando, Ventoruzzo, Giorgio, Mazzitelli, Giulia, Ragni, Franco, Bozzani, Antonio, Forliti, Enzo, Castagno, Claudio, Volpe, Pietro, Massara, Mafalda, Moniaci, Diego, Pagliasso, Elisa, Peretti, Tania, Ferrari, Mauro, Troisi, Nicola, Modugno, Piero, Maiorano, Maurizio, Bracale, Umberto M., Panagrosso, Marco, Monaco, Mario, Giordano, Giovanni, Natalicchio, Giuseppe, Biello, Antonella, Celoria, Giovanni M., Amico, Alessio, Di Bartolo, Mauro, Martelli, Massimiliano, Munaó, Roberta, Razzano, Davide, Colacchio, Giovanni, Bussetti, Francesco, Lanza, Gaetano, Cardini, Antonio, Di Benedetto, Bartolomeo, De Laurentis, Mario, Taurino, Maurizio, Sirignano, Pasqualino, Cappiello, Pierluigi, Esposito, Andrea, Trimarchi, Santi, Romagnoli, Silvia, Padricelli, Andrea, Giudice, Giorgio, Crinisio, Adolfo, Di Nardo, Giovanni, Battaglia, Giuseppe, Tringale, Rosario, De Vivo, Salvatore, Compagna, Rita, Tolva, Valerio S., D’Alessio, Ilenia, Curci, Ruggiero, Giovannetti, Simona, D’Arrigo, Giuseppe, Basile, Giusi, Frigerio, Dalmazio, Veraldi, Gian Franco, Mezzetto, Luca, Ippoliti, Arnaldo, Oddi, Fabio M., and Settembrini, Alberto M.

Subjects
chronic limb-threatening ischemia, age, limb salvage, outcome, sex, Medicine (miscellaneous), Settore MED/09
Abstract

Background: Identifying sex-related differences/variables associated with 30 day/1 year mortality in patients with chronic limb-threatening ischemia (CLTI). Methods: Multicenter/retrospective/observational study. A database was sent to all the Italian vascular surgeries to collect all the patients operated on for CLTI in 2019. Acute lower-limb ischemia and neuropathic-diabetic foot are not included. Follow-up: One year. Data on demographics/comorbidities, treatments/outcomes, and 30 day/1 year mortality were investigated. Results: Information on 2399 cases (69.8% men) from 36/143 (25.2%) centers. Median (IQR) age: 73 (66–80) and 79 (71–85) years for men/women, respectively (p < 0.0001). Women were more likely to be over 75 (63.2% vs. 40.1%, p = 0.0001). More men smokers (73.7% vs. 42.2%, p < 0.0001), are on hemodialysis (10.1% vs. 6.7%, p = 0.006), affected by diabetes (61.9% vs. 52.8%, p < 0.0001), dyslipidemia (69.3% vs. 61.3%, p < 0.0001), hypertension (91.8% vs. 88.5%, p = 0.011), coronaropathy (43.9% vs. 29.4%, p < 0.0001), bronchopneumopathy (37.1% vs. 25.6%, p < 0.0001), underwent more open/hybrid surgeries (37.9% vs. 28.8%, p < 0.0001), and minor amputations (22% vs. 13.7%, p < 0.0001). More women underwent endovascular revascularizations (61.6% vs. 55.2%, p = 0.004), major amputations (9.6% vs. 6.9%, p = 0.024), and obtained limb-salvage if with limited gangrene (50.8% vs. 44.9%, p = 0.017). Age > 75 (HR = 3.63, p = 0.003) is associated with 30 day mortality. Age > 75 (HR = 2.14, p < 0.0001), nephropathy (HR = 1.54, p < 0.0001), coronaropathy (HR = 1.26, p = 0.036), and infection/necrosis of the foot (dry, HR = 1.42, p = 0.040; wet, HR = 2.04, p < 0.0001) are associated with 1 year mortality. No sex-linked difference in mortality statistics. Conclusion: Women exhibit fewer comorbidities but are struck by CLTI when over 75, a factor associated with short- and mid-term mortality, explaining why mortality does not statistically differ between the sexes.

Published
2023

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