Search

Your search keyword '"Capone, Valentina"' showing total 196 results
Start Over Author "Capone, Valentina"
196 results on '"Capone, Valentina"'

3. Management of the congenital solitary kidney: consensus recommendations of the Italian Society of Pediatric Nephrology

Author

La Scola, Claudio, Ammenti, Anita, Bertulli, Cristina, Bodria, Monica, Brugnara, Milena, Camilla, Roberta, and Capone, Valentina

Subjects
Birth defects -- Care and treatment, Practice guidelines (Medicine) -- Evaluation, Kidneys -- Abnormalities, Health
Abstract

Background In recent years, several studies have been published on the prognosis of children with congenital solitary kidney (CSK), with controversial results, and a worldwide consensus on management and follow-up is lacking. In this consensus statement, the Italian Society of Pediatric Nephrology summarizes the current knowledge on CSK and presents recommendations for its management, including diagnostic approach, nutritional and lifestyle habits, and follow-up. Summary of the recommendations We recommend that any antenatal suspicion/diagnosis of CSK be confirmed by neonatal ultrasound (US), avoiding the routine use of further imaging if no other anomalies of kidney/urinary tract are detected. A CSK without additional abnormalities is expected to undergo compensatory enlargement, which should be assessed by US. We recommend that urinalysis, but not blood tests or genetic analysis, be routinely performed at diagnosis in infants and children showing compensatory enlargement of the CSK. Extrarenal malformations should be searched for, particularly genital tract malformations in females. An excessive protein and salt intake should be avoided, while sport participation should not be restricted. We recommend a lifelong follow-up, which should be tailored on risk stratification, as follows: low risk: CSK with compensatory enlargement, medium risk: CSK without compensatory enlargement and/or additional CAKUT, and high risk: decreased GFR and/or proteinuria, and/or hypertension. We recommend that in children at low-risk periodic US, urinalysis and BP measurement be performed; in those at medium risk, we recommend that serum creatinine also be measured; in high-risk children, the schedule has to be tailored according to kidney function and clinical data., Author(s): Claudio La Scola [sup.1] , Anita Ammenti [sup.2] , Cristina Bertulli [sup.1] , Monica Bodria [sup.3] , Milena Brugnara [sup.4] , Roberta Camilla [sup.5] , Valentina Capone [sup.6] , [...]

Published
2022
Full Text
View/download PDF

4. The copy number variation landscape of congenital anomalies of the kidney and urinary tract.

Author

Verbitsky, Miguel, Westland, Rik, Perez, Alejandra, Kiryluk, Krzysztof, Liu, Qingxue, Krithivasan, Priya, Mitrotti, Adele, Fasel, David, Batourina, Ekaterina, Sampson, Matthew, Bodria, Monica, Werth, Max, Kao, Charlly, Martino, Jeremiah, Capone, Valentina, Vivante, Asaf, Shril, Shirlee, Kil, Byum, Marasà, Maddalena, Zhang, Jun, Na, Young-Ji, Lim, Tze, Ahram, Dina, Weng, Patricia, Heinzen, Erin, Carrea, Alba, Piaggio, Giorgio, Gesualdo, Loreto, Manca, Valeria, Masnata, Giuseppe, Gigante, Maddalena, Cusi, Daniele, Izzi, Claudia, Scolari, Francesco, van Wijk, Joanna, Saraga, Marijan, Santoro, Domenico, Conti, Giovanni, Zamboli, Pasquale, White, Hope, Drozdz, Dorota, Zachwieja, Katarzyna, Miklaszewska, Monika, Tkaczyk, Marcin, Tomczyk, Daria, Krakowska, Anna, Sikora, Przemyslaw, Jarmoliński, Tomasz, Borszewska-Kornacka, Maria, Pawluch, Robert, Szczepanska, Maria, Adamczyk, Piotr, Mizerska-Wasiak, Malgorzata, Krzemien, Grazyna, Szmigielska, Agnieszka, Zaniew, Marcin, Dobson, Mark, Darlow, John, Puri, Prem, Barton, David, Furth, Susan, Warady, Bradley, Gucev, Zoran, Lozanovski, Vladimir, Tasic, Velibor, Pisani, Isabella, Allegri, Landino, Rodas, Lida, Campistol, Josep, Jeanpierre, Cécile, Alam, Shumyle, Casale, Pasquale, Wong, Craig, Lin, Fangming, Miranda, Débora, Oliveira, Eduardo, Simões-E-Silva, Ana, Barasch, Jonathan, Levy, Brynn, Wu, Nan, Hildebrandt, Friedhelm, Ghiggeri, Gian, Latos-Bielenska, Anna, Materna-Kiryluk, Anna, Zhang, Feng, Hakonarson, Hakon, Papaioannou, Virginia, Mendelsohn, Cathy, Gharavi, Ali, and Sanna-Cherchi, Simone

Subjects
Chromosome Deletion, DNA Copy Number Variations, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Kidney, Male, Urinary Tract, Urogenital Abnormalities, Vesico-Ureteral Reflux
Abstract

Congenital anomalies of the kidney and urinary tract (CAKUT) are a major cause of pediatric kidney failure. We performed a genome-wide analysis of copy number variants (CNVs) in 2,824 cases and 21,498 controls. Affected individuals carried a significant burden of rare exonic (that is, affecting coding regions) CNVs and were enriched for known genomic disorders (GD). Kidney anomaly (KA) cases were most enriched for exonic CNVs, encompassing GD-CNVs and novel deletions; obstructive uropathy (OU) had a lower CNV burden and an intermediate prevalence of GD-CNVs; and vesicoureteral reflux (VUR) had the fewest GD-CNVs but was enriched for novel exonic CNVs, particularly duplications. Six loci (1q21, 4p16.1-p16.3, 16p11.2, 16p13.11, 17q12 and 22q11.2) accounted for 65% of patients with GD-CNVs. Deletions at 17q12, 4p16.1-p16.3 and 22q11.2 were specific for KA; the 16p11.2 locus showed extensive pleiotropy. Using a multidisciplinary approach, we identified TBX6 as a driver for the CAKUT subphenotypes in the 16p11.2 microdeletion syndrome.

Published
2019

5. Rare Single Nucleotide and Copy Number Variants and the Etiology of Congenital Obstructive Uropathy: Implications for Genetic Diagnosis

Author

Ahram, Dina F., Lim, Tze Y., Ke, Juntao, Jin, Gina, Verbitsky, Miguel, Bodria, Monica, Kil, Byum Hee, Chatterjee, Debanjana, Piva, Stacy E., Marasa, Maddalena, Zhang, Jun Y., Cocchi, Enrico, Caridi, Gianluca, Gucev, Zoran, Lozanovski, Vladimir J., Pisani, Isabella, Izzi, Claudia, Savoldi, Gianfranco, Gnutti, Barbara, Capone, Valentina P., Morello, William, Guarino, Stefano, Esposito, Pasquale, Lambert, Sarah, Radhakrishnan, Jai, Appel, Gerald B., Uy, Natalie S., Rao, Maya K., Canetta, Pietro A., Bomback, Andrew S., Nestor, Jordan G., Hays, Thomas, Cohen, David J., Finale, Carolina, Wijk, Joanna A.E. van, La Scola, Claudio, Baraldi, Olga, Tondolo, Francesco, Di Renzo, Dacia, Jamry-Dziurla, Anna, Pezzutto, Alessandro, Manca, Valeria, Mitrotti, Adele, Santoro, Domenico, Conti, Giovanni, Martino, Marida, Giordano, Mario, Gesualdo, Loreto, Zibar, Lada, Masnata, Giuseppe, Bonomini, Mario, Alberti, Daniele, La Manna, Gaetano, Caliskan, Yasar, Ranghino, Andrea, Marzuillo, Pierluigi, Kiryluk, Krzysztof, Krzemień, Grażyna, Miklaszewska, Monika, Lin, Fangming, Montini, Giovanni, Scolari, Francesco, Fiaccadori, Enrico, Arapović, Adela, Saraga, Marijan, McKiernan, James, Alam, Shumyle, Zaniew, Marcin, Szczepańska, Maria, Szmigielska, Agnieszka, Sikora, Przemysław, Drożdż, Dorota, Mizerska-Wasiak, Malgorzata, Mane, Shrikant, Lifton, Richard P., Tasic, Velibor, Latos-Bielenska, Anna, Gharavi, Ali G., Ghiggeri, Gian Marco, Materna-Kiryluk, Anna, Westland, Rik, and Sanna-Cherchi, Simone

Published
2023
Full Text
View/download PDF

6. Definition, diagnosis and management of fetal lower urinary tract obstruction: consensus of the ERKNet CAKUT-Obstructive Uropathy Work Group

Author

Capone, Valentina, Persico, Nicola, Berrettini, Alfredo, Decramer, Stèphane, De Marco, Erika Adalgisa, De Palma, Diego, Familiari, Alessandra, Feitz, Wout, Herthelius, Maria, Kazlauskas, Vytis, Liebau, Max, Manzoni, Gianantonio, Maternik, Michal, Mosiello, Giovanni, Schanstra, Joost Peter, Vande Walle, Johan, Wühl, Elke, Ylinen, Elisa, Zurowska, Aleksandra, Schaefer, Franz, and Montini, Giovanni

Published
2022
Full Text
View/download PDF

8. The Role of Vericiguat in Early Phases of Anterior Myocardial Infarction: A Potential Game-Changer?

Author

Cacciapuoti, Federico, Mauro, Ciro, Capone, Valentina, Chianese, Salvatore, Tarquinio, Luca Gaetano, Gottilla, Rossella, Marsico, Fabio, Crispo, Salvatore, and Cacciapuoti, Fulvio

Subjects
ANTERIOR wall myocardial infarction, CYCLIC guanylic acid, HEART failure, GUANYLATE cyclase, MYOCARDIUM, MYOCARDIAL infarction
Abstract

Anterior myocardial infarction is a critical condition with significant implications for cardiac function and patient prognosis. Despite advancements in reperfusion therapies, optimizing recovery during the early phases of myocardial infarction remains challenging. Anterior myocardial infarction can lead to substantial long-term effects on a patient's health due to extensive damage to the heart muscle, particularly the left ventricle, impacting both quality of life and overall prognosis. Vericiguat, a soluble guanylate cyclase stimulator, has shown promise in heart failure, but its role in early anterior myocardial infarction has not yet been fully explored. By enhancing soluble guanylate cyclase activity, vericiguat may increase cyclic guanosine monophosphate production, leading to vasodilation, inhibition of platelet aggregation, and potential cardioprotective effects. Currently, treatment options for anterior myocardial infarction primarily focus on reperfusion strategies and managing complications. However, there is a critical need for adjunctive therapies that specifically target the pathophysiological changes occurring in the early phases of myocardial infarction. Vericiguat's mechanism of action offers a novel approach to improving vascular function and myocardial health, potentially contributing to innovative treatment strategies that could transform the care and prognosis of patients with anterior myocardial infarction. [ABSTRACT FROM AUTHOR]

Published
2024
Full Text
View/download PDF

11. Multiple, random spot urine sampling for estimating urinary sodium excretion

Author

Ardissino, Gianluigi, Vergori, Antonio, Vergori, Cesare, Martelli, Laura, Daccò, Valeria, Villa, Maria Cristina, Masciani, Martino, Monzani, Alice, Salice, Patrizia, Ghiglia, Silvia, Perrone, Michela, Capone, Valentina, Mancuso, Maria Cristina, Giussani, Antenore, Pieri, Giovanni Raimondo, Bosco, Annalisa, Brambilla, Marta, Romano, Roberto, Rotondo, Stefania, and Buzzetti, Roberto

Published
2022
Full Text
View/download PDF

12. Kidney transplant in patients with atypical hemolytic uremic syndrome in the anti-C5 era: single-center experience with tailored Eculizumab

Author

Ardissino, Gianluigi, Cresseri, Donata, Tel, Francesca, Giussani, Antenore, Salardi, Stefania, Sgarbanti, Martina, Strumbo, Bice, Testa, Sara, Capone, Valentina, Griffini, Samantha, Grovetti, Elena, Cugno, Massimo, Belingheri, Mirco, Tamburello, Chiara, Rodrigues, Evangeline Millicent, Perrone, Michela, Cardillo, Massimo, Corti, Grazia, Consonni, Dario, Furian, Lucrezia, Tedeschi, Silvana, Messa, Piergiorgio, and Beretta, Claudio

Published
2021
Full Text
View/download PDF

13. Fenoldopam and renal hemodynamics in shiga toxin-related hemolytic uremic syndrome

Author

Ardissino, Gianluigi, Giussani, Antenore, Capone, Valentina, Testa, Sara, Gandini, Cristiano, and Montini, Giovanni

Subjects
Hemolytic-uremic syndrome -- Drug therapy, Fenoldopam -- Usage, Hemodynamics -- Health aspects, Health
Abstract

Background Fenoldopam, a vasodilating agent, may represent a potential therapeutic opportunity to increase renal perfusion in those conditions where renal hemodynamics are severely impaired by vascular sub-occlusion, as, indeed, is the case in thrombotic microangiopathies. Methods The renal resistance index (RRI) was measured, on and off fenoldopam, in 27 children with STEC-HUS. Results A 12% decrease in RRI was observed on fenoldopam compared to off treatment without changes in the systemic hemodynamics and with no side effects. Conclusions If confirmed in larger series, fenoldopam may become an important addition to supportive care to reduce ischemic damage in STEC-HUS and improve long-term outcomes., Author(s): Gianluigi Ardissino [sup.1] , Antenore Giussani [sup.2] , Valentina Capone [sup.1] , Sara Testa [sup.1] , Cristiano Gandini [sup.3] , Giovanni Montini [sup.1] Author Affiliations: (1) grid.414818.0, 0000 0004 [...]

Published
2021
Full Text
View/download PDF

15. Risk of Atypical HUS Among Family Members of Patients Carrying Complement Regulatory Gene Abnormality

Author

Ardissino, Gianluigi, Longhi, Selena, Porcaro, Luigi, Pintarelli, Giulia, Strumbo, Bice, Capone, Valentina, Cresseri, Donata, Loffredo, Giulia, Tel, Francesca, Salardi, Stefania, Sgarbanti, Martina, Martelli, Laura, Rodrigues, Evangeline Millicent, Borsa-Ghiringhelli, Nicolò, Montini, Giovanni, Seia, Manuela, Cugno, Massimo, Carfagna, Fabio, Consonni, Dario, and Tedeschi, Silvana

Published
2021
Full Text
View/download PDF

17. Is Shigatoxin 1 protective for the development of Shigatoxin 2-related hemolytic uremic syndrome in children? Data from the ItalKid-HUS Network

Author

Ardissino, Gianluigi, Possenti, Ilaria, Vignati, Chiara, Daprai, Laura, Capone, Valentina, Brigotti, Maurizio, and Luini, Mario Vittorio

Subjects
Children -- Diseases, Hemolytic-uremic syndrome -- Diagnosis -- Risk factors, Health
Abstract

Background Shigatoxin (Stx)-producing Escherichia coli (STEC) are the most common causes of hemolytic uremic syndrome (STEC-HUS). The aim of our study is to compare the risk of developing STEC-HUS in relation to the type of Stx genes (Stx1, Stx2, or both). Methods This is a prospective, observational, multicenter study involving 63 pediatric units in Northern Italy (ItalKid-HUS Network). STEC-infected children were identified within a screening program for bloody diarrhea during a 10-year period (2010-2019). Stx genes were detected by reverse dot blot or real-time PCR. After the identification of STEC infection, children were followed until diarrhea complete recovery for the possible development of STEC-HUS. Results Of the 214 Stx-positive patients, 34 (15.9%) developed STEC-HUS. The risk of HUS in STEC-infected children with Stx1 (n: 62; 29.0%) and Stx2 (n: 97; 45.3%) was respectively 0% and 23.7%, while in patients carrying both Stx1 and Stx2 (n: 55; 25.7%), the risk was 12.7% (p: 0.001). Conclusions Our data confirm that Stx1 is a very rare cause of STEC-HUS and demonstrate that the risk of STEC-HUS halves in the case of Stx1+2-producing Escherichia coli infection compared with infections where Stx2 is present alone. This observation is helpful in assessing the risk of individual STEC-infected patients for the development of HUS and suggests that Stx1, in the presence of Stx2, might exert a protective role possibly by receptor competition., Author(s): Gianluigi Ardissino [sup.1] , Ilaria Possenti [sup.2] , Chiara Vignati [sup.3] , Laura Daprai [sup.3] , Valentina Capone [sup.1] , Maurizio Brigotti [sup.4] , Mario Vittorio Luini [sup.5] , [...]

Published
2020
Full Text
View/download PDF

18. Exercise Stress Echocardiography of the Right Ventricle and Pulmonary Circulation

Author

Gargani, Luna, primary, Pugliese, Nicola Riccardo, additional, De Biase, Nicolò, additional, Mazzola, Matteo, additional, Agoston, Gergely, additional, Arcopinto, Michele, additional, Argiento, Paola, additional, Armstrong, William F., additional, Bandera, Francesco, additional, Cademartiri, Filippo, additional, Carbone, Andreina, additional, Castaldo, Rossana, additional, Citro, Rodolfo, additional, Cocchia, Rosangela, additional, Codullo, Veronica, additional, D’Alto, Michele, additional, D'Andrea, Antonello, additional, Douschan, Philipp, additional, Fabiani, Iacopo, additional, Ferrara, Francesco, additional, Franzese, Monica, additional, Frumento, Paolo, additional, Ghio, Stefano, additional, Grünig, Ekkehard, additional, Guazzi, Marco, additional, Kasprzak, Jaroslaw D., additional, Kolias, Theodore, additional, Kovacs, Gabor, additional, La Gerche, André, additional, Limogelli, Giuseppe, additional, Marra, Alberto Maria, additional, Matucci-Cerinic, Marco, additional, Mauro, Ciro, additional, Moreo, Antonella, additional, Pratali, Lorenza, additional, Ranieri, Brigida, additional, Rega, Salvatore, additional, Rudski, Lawrence, additional, Saggar, Rajan, additional, Salzano, Andrea, additional, Serra, Walter, additional, Stanziola, Anna A., additional, Vannan, Mani A., additional, Voilliot, Damien, additional, Vriz, Olga, additional, Wierzbowska-Drabik, Karina, additional, Cittadini, Antonio, additional, Naeije, Robert, additional, Bossone, Eduardo, additional, Gargani, Luna, additional, Kolias, Theodore John, additional, Capone, Valentina, additional, Sepe, Chiara, additional, Capuano, Francesco, additional, Benvenga, Rossella, additional, Bellino, Michele, additional, Iuliano, Giuseppe, additional, Migliarino, Serena, additional, Radano, Ilaria, additional, Marra, Alberto, additional, Crisci, Giulia, additional, D’Assante, Roberta, additional, De Luca, Mariarosaria, additional, Giardino, Federica, additional, Rainone, Carmen, additional, Valente, Valeria, additional, D’Andrea, Antonello, additional, Russo, Valentina, additional, Dellegrottaglie, Santo, additional, Di Salvo, Giovanni, additional, Guida, Stefania, additional, Grunig, Ekkerard, additional, Eichstaedt, Christina A., additional, Labate, Valentina, additional, La Gerch, André, additional, Limongelli, Giuseppe, additional, Pacileo, Giuseppe, additional, Verrengia, Marina, additional, Casadei, Francesca, additional, De Chiara, Benedetta, additional, Ostenfeld, Ellen, additional, Pedrizzetti, Gianni, additional, Pieri, Francesco, additional, Mori, Fabio, additional, Moggi-Pignone, Alberto, additional, Raciti, Mauro, additional, Pugliese, Nicola, additional, D’Angelo, Gennaro, additional, Stanziola, Anna Agnese, additional, Rossella, D’Angelo, additional, Gallotta, Lorena, additional, Szabó, István, additional, Varga, Albert, additional, Galzerano, Domenico, additional, Vannan, Mani, additional, Mobasseri, Sara, additional, Flueckiger, Peter, additional, and Liu, Shizhen, additional

Published
2023
Full Text
View/download PDF

22. Cardiovascular Side Effects of Anthracyclines and HER2 Inhibitors among Patients with Breast Cancer: A Multidisciplinary Stepwise Approach for Prevention, Early Detection, and Treatment

Author

Mauro, Ciro, primary, Capone, Valentina, additional, Cocchia, Rosangela, additional, Cademartiri, Filippo, additional, Riccardi, Ferdinando, additional, Arcopinto, Michele, additional, Alshahid, Maie, additional, Anwar, Kashif, additional, Carafa, Mariano, additional, Carbone, Andreina, additional, Castaldo, Rossana, additional, Chianese, Salvatore, additional, Crisci, Giulia, additional, D’Assante, Roberta, additional, De Luca, Mariarosaria, additional, Franzese, Monica, additional, Galzerano, Domenico, additional, Maffei, Vincenzo, additional, Marra, Alberto M., additional, Valente, Valeria, additional, Giardino, Federica, additional, Mazza, Alfredo, additional, Ranieri, Brigida, additional, D’Agostino, Anna, additional, Rega, Salvatore, additional, Romano, Luigia, additional, Scagliarini, Sarah, additional, Sepe, Chiara, additional, Vriz, Olga, additional, Izzo, Raffaele, additional, Cittadini, Antonio, additional, Bossone, Eduardo, additional, and Salzano, Andrea, additional

Published
2023
Full Text
View/download PDF

23. Exploring the Cardiotoxicity Spectrum of Anti-Cancer Treatments: Definition, Classification, and Diagnostic Pathways

Author

Mauro, Ciro, primary, Capone, Valentina, additional, Cocchia, Rosangela, additional, Cademartiri, Filippo, additional, Riccardi, Ferdinando, additional, Arcopinto, Michele, additional, Alshahid, Maie, additional, Anwar, Kashif, additional, Carafa, Mariano, additional, Carbone, Andreina, additional, Castaldo, Rossana, additional, Chianese, Salvatore, additional, Crisci, Giulia, additional, D’Assante, Roberta, additional, De Luca, Mariarosaria, additional, Franzese, Monica, additional, Galzerano, Domenico, additional, Maffei, Vincenzo, additional, Marra, Alberto Maria, additional, Mazza, Alfredo, additional, Ranieri, Brigida, additional, D’Agostino, Anna, additional, Rega, Salvatore, additional, Romano, Luigia, additional, Scagliarini, Sarah, additional, Sepe, Chiara, additional, Vriz, Olga, additional, Izzo, Raffaele, additional, Cittadini, Antonio, additional, Bossone, Eduardo, additional, and Salzano, Andrea, additional

Published
2023
Full Text
View/download PDF

24. Acute Heart Failure: Diagnostic–Therapeutic Pathways and Preventive Strategies—A Real-World Clinician’s Guide

Author

Mauro, Ciro, primary, Chianese, Salvatore, additional, Cocchia, Rosangela, additional, Arcopinto, Michele, additional, Auciello, Stefania, additional, Capone, Valentina, additional, Carafa, Mariano, additional, Carbone, Andreina, additional, Caruso, Giuseppe, additional, Castaldo, Rossana, additional, Citro, Rodolfo, additional, Crisci, Giulia, additional, D’Andrea, Antonello, additional, D’Assante, Roberta, additional, D’Avino, Maria, additional, Ferrara, Francesco, additional, Frangiosa, Antonio, additional, Galzerano, Domenico, additional, Maffei, Vincenzo, additional, Marra, Alberto Maria, additional, Mehta, Rahul M., additional, Mehta, Rajendra H., additional, Paladino, Fiorella, additional, Ranieri, Brigida, additional, Franzese, Monica, additional, Limongelli, Giuseppe, additional, Rega, Salvatore, additional, Romano, Luigia, additional, Salzano, Andrea, additional, Sepe, Chiara, additional, Vriz, Olga, additional, Izzo, Raffaele, additional, Cademartiri, Filippo, additional, Cittadini, Antonio, additional, and Bossone, Eduardo, additional

Published
2023
Full Text
View/download PDF

27. Supplement to: Genetic drivers of kidney defects in the DiGeorge syndrome.

Author

Lopez-Rivera, Esther, Liu, Yangfan P., Verbitsky, Miguel, Anderson, Blair R., Capone, Valentina P., Otto, Edgar A., Yan, Zhonghai, Mitrotti, Adele, Martino, Jeremiah, Steers, Nicholas J., Fasel, David A., Vukojevic, Katarina, Deng, Rong, Racedo, Silvia E., Liu, Qingxue, Werth, Max, Westland, Rik, Vivante, Asaf, Makar, Gabriel S., Bodria, Monica, Sampson, Matthew G., Gillies, Christopher E., Vega-Warner, Virginia, Maiorana, Mariarosa, Petrey, Donald S., Honig, Barry, Lozanovski, Vladimir J., Salomon, Rémi, Heidet, Laurence, Carpentier, Wassila, Gaillard, Dominique, Carrea, Alba, Gesualdo, Loreto, Cusi, Daniele, Izzi, Claudia, Scolari, Francesco, van Wijk, Joanna A.E., Arapovic, Adela, Saraga-Babic, Mirna, Saraga, Marijan, Kunac, Nenad, Samii, Ali, McDonald-McGinn, Donna M., Crowley, Terrence B., Zackai, Elaine H., Drosdz, Dorota, Miklaszewska, Monika, Tkaczyk, Marcin, Sikora, Przemyslaw, Szczepanska, Maria, Mizerska-Wasiak, Malgorzata, Krzemien, Grazyna, Szmigielska, Agnieszka, Zaniew, Marcin, Darlow, John M., Puri, Prem, Barton, David, Casolari, Emilio, Furth, Susan L., Warady, Bradley A., Gucev, Zoran, Hakonarson, Hakon, Flogelova, Hana, Tasic, Velibor, Bielenska, Anna Latos, Materna-Kiryluk, Anna, Allegri, Landino, Wong, Craig S., Drummond, Iain A., DʼAgati, Vivette, Imamoto, Akira, Barasch, Jonathan M., Hildebrandt, Friedhelm, Kiryluk, Krzysztof, Lifton, Richard P., Morrow, Bernice E., Jeanpierre, Cecile, Papaioannou, Virginia E., Ghiggeri, Gian Marco, Gharavi, Ali G., Katsanis, Nicholas, and Sanna-Cherchi, Simone

Published
2017

28. Severe Stenosis of Mitral Bioprosthetic Valve Thrombosis in a Patient with HCV-Related Cirrhosis and Duodenal Variceal Bleeding: The Deadly Triad

Author

Cocchia, Rosangela, primary, Chianese, Salvatore, additional, Lombardi, Giovanni, additional, Romano, Luigia, additional, Capone, Valentina, additional, Amitrano, Lucio, additional, Bennato, Raffaele, additional, Ranieri, Brigida, additional, Russo, Giuseppe, additional, Mauro, Ciro, additional, and Bossone, Eduardo, additional

Published
2022
Full Text
View/download PDF

29. Effects of Exercise on Heart Failure with Preserved Ejection Fraction: An Updated Review of Literature

Author

Crisci, Giulia, primary, De Luca, Mariarosaria, additional, D’Assante, Roberta, additional, Ranieri, Brigida, additional, D’Agostino, Anna, additional, Valente, Valeria, additional, Giardino, Federica, additional, Capone, Valentina, additional, Chianese, Salvatore, additional, Rega, Salvatore, additional, Cocchia, Rosangela, additional, Israr, Muhammad Zubair, additional, Debiek, Radek, additional, Heaney, Liam M., additional, and Salzano, Andrea, additional

Published
2022
Full Text
View/download PDF

31. Definition, diagnosis and clinical management of non-obstructive kidney dysplasia: a consensus statement by the ERKNet Working Group on Kidney Malformations

Author

Kohl, Stefan, primary, Avni, Fred E, additional, Boor, Peter, additional, Capone, Valentina, additional, Clapp, William L, additional, De Palma, Diego, additional, Harris, Tess, additional, Heidet, Laurence, additional, Hilger, Alina C, additional, Liapis, Helen, additional, Lilien, Marc, additional, Manzoni, Gianantonio, additional, Montini, Giovanni, additional, Negrisolo, Susanna, additional, Pierrat, Marie-Jeanne, additional, Raes, Ann, additional, Reutter, Heiko, additional, Schreuder, Michiel F, additional, Weber, Stefanie, additional, Winyard, Paul J D, additional, Woolf, Adrian S, additional, Schaefer, Franz, additional, and Liebau, Max C, additional

Published
2022
Full Text
View/download PDF

32. Physiologic Range of Myocardial Mechano-Energetic Efficiency among Healthy Subjects: Impact of Gender and Age

Author

Ferrara, Francesco, primary, Capone, Valentina, additional, Cademartiri, Filippo, additional, Vriz, Olga, additional, Cocchia, Rosangela, additional, Ranieri, Brigida, additional, Franzese, Monica, additional, Castaldo, Rossana, additional, D’Andrea, Antonello, additional, Citro, Rodolfo, additional, Chianese, Salvatore, additional, Annunziata, Roberto, additional, Marullo, Flavio, additional, Siniscalchi, Mario, additional, Conte, Marianna, additional, Sepe, Chiara, additional, Maramaldi, Renato, additional, Rega, Salvatore, additional, Russo, Giuseppe, additional, Majolo, Massimo, additional, Raiola, Eliana, additional, Salzano, Andrea, additional, Mauro, Ciro, additional, Trimarco, Bruno, additional, Izzo, Raffaele, additional, and Bossone, Eduardo, additional

Published
2022
Full Text
View/download PDF

33. Definition, diagnosis and clinical management of non-obstructive kidney dysplasia: a consensus statement by the ERKNet Working Group on Kidney Malformations

Author

Kohl, Stefan, Avni, Fred E., Boor, Peter, Capone, Valentina, Clapp, William L., De Palma, Diego, Harris, Tess, Heidet, Laurence, Hilger, Alina C., Liapis, Helen, Lilien, Marc, Manzoni, Gianantonio, Montini, Giovanni, Negrisolo, Susanna, Pierrat, Marie-Jeanne, Raes, Ann, Reutter, Heiko, Schreuder, Michiel F., Weber, Stefanie, Winyard, Paul J. D., Woolf, Adrian S., Schaefer, Franz, Liebau, Max C., Kohl, Stefan, Avni, Fred E., Boor, Peter, Capone, Valentina, Clapp, William L., De Palma, Diego, Harris, Tess, Heidet, Laurence, Hilger, Alina C., Liapis, Helen, Lilien, Marc, Manzoni, Gianantonio, Montini, Giovanni, Negrisolo, Susanna, Pierrat, Marie-Jeanne, Raes, Ann, Reutter, Heiko, Schreuder, Michiel F., Weber, Stefanie, Winyard, Paul J. D., Woolf, Adrian S., Schaefer, Franz, and Liebau, Max C.

Abstract

Kidney dysplasia is one of the most frequent causes of chronic kidney failure in children. While dysplasia is a histological diagnosis, the term 'kidney dysplasia' is frequently used in daily clinical life without histopathological confirmation. Clinical parameters of kidney dysplasia have not been clearly defined, leading to imprecise communication amongst healthcare professionals and patients. This lack of consensus hampers precise disease understanding and the development of specific therapies. Based on a structured literature search, we here suggest a common basis for clinical, imaging, genetic, pathological and basic science aspects of non-obstructive kidney dysplasia associated with functional kidney impairment. We propose to accept hallmark sonographic findings as surrogate parameters defining a clinical diagnosis of dysplastic kidneys. We suggest differentiated clinical follow-up plans for children with kidney dysplasia and summarize established monogenic causes for non-obstructive kidney dysplasia. Finally, we point out and discuss research gaps in the field.

Published
2022

34. Definition, diagnosis and clinical management of non-obstructive kidney dysplasia: a consensus statement by the ERKNet Working Group on Kidney Malformations

Author

Nefrologie, Child Health, Kohl, Stefan, Avni, Fred E, Boor, Peter, Capone, Valentina, Clapp, William L, De Palma, Diego, Harris, Tess, Heidet, Laurence, Hilger, Alina C, Liapis, Helen, Lilien, Marc, Manzoni, Gianantonio, Montini, Giovanni, Negrisolo, Susanna, Pierrat, Marie-Jeanne, Raes, Ann, Reutter, Heiko, Schreuder, Michiel F, Weber, Stefanie, Winyard, Paul J D, Woolf, Adrian S, Schaefer, Franz, Liebau, Max C, Nefrologie, Child Health, Kohl, Stefan, Avni, Fred E, Boor, Peter, Capone, Valentina, Clapp, William L, De Palma, Diego, Harris, Tess, Heidet, Laurence, Hilger, Alina C, Liapis, Helen, Lilien, Marc, Manzoni, Gianantonio, Montini, Giovanni, Negrisolo, Susanna, Pierrat, Marie-Jeanne, Raes, Ann, Reutter, Heiko, Schreuder, Michiel F, Weber, Stefanie, Winyard, Paul J D, Woolf, Adrian S, Schaefer, Franz, and Liebau, Max C

Published
2022

35. Genetic Drivers of Kidney Defects in the DiGeorge Syndrome

Author

Lopez-Rivera, Esther, Liu, Yangfan P., Verbitsky, Miguel, Anderson, Blair R., Capone, Valentina P., Otto, Edgar A., Yan, Zhonghai, Mitrotti, Adele, Martino, Jeremiah, Steers, Nicholas J., Fasel, David A., Vukojevic, Katarina, Deng, Rong, Racedo, Silvia E., Liu, Qingxue, Werth, Max, Westland, Rik, Vivante, Asaf, Makar, Gabriel S., Bodria, Monica, Sampson, Matthew G., Gillies, Christopher E., Vega-Warner, Virginia, Maiorana, Mariarosa, Petrey, Donald S., Honig, Barry, Lozanovski, Vladimir J., Salomon, Rémi, Heidet, Laurence, Carpentier, Wassila, Gaillard, Dominique, Carrea, Alba, Gesualdo, Loreto, Cusi, Daniele, Izzi, Claudia, Scolari, Francesco, van Wijk, Joanna A.E., Arapovic, Adela, Saraga-Babic, Mirna, Saraga, Marijan, Kunac, Nenad, Samii, Ali, McDonald-McGinn, Donna M., Crowley, Terrence B., Zackai, Elaine H., Drozdz, Dorota, Miklaszewska, Monika, Tkaczyk, Marcin, Sikora, Przemyslaw, Szczepanska, Maria, Mizerska-Wasiak, Malgorzata, Krzemien, Grazyna, Szmigielska, Agnieszka, Zaniew, Marcin, Darlow, John M., Puri, Prem, Barton, David, Casolari, Emilio, Furth, Susan L., Warady, Bradley A., Gucev, Zoran, Hakonarson, Hakon, Flogelova, Hana, Tasic, Velibor, Latos-Bielenska, Anna, Materna-Kiryluk, Anna, Allegri, Landino, Wong, Craig S., Drummond, Iain A., DʼAgati, Vivette, Imamoto, Akira, Barasch, Jonathan M., Hildebrandt, Friedhelm, Kiryluk, Krzysztof, Lifton, Richard P., Morrow, Bernice E., Jeanpierre, Cecile, Papaioannou, Virginia E., Ghiggeri, Gian Marco, Gharavi, Ali G., Katsanis, Nicholas, and Sanna-Cherchi, Simone

Published
2017
Full Text
View/download PDF

36. Author Correction: The copy number variation landscape of congenital anomalies of the kidney and urinary tract

Author

Verbitsky, Miguel, Westland, Rik, Perez, Alejandra, Kiryluk, Krzysztof, Liu, Qingxue, Krithivasan, Priya, Mitrotti, Adele, Fasel, David A., Batourina, Ekaterina, Sampson, Matthew G., Bodria, Monica, Werth, Max, Kao, Charlly, Martino, Jeremiah, Capone, Valentina P., Vivante, Asaf, Shril, Shirlee, Kil, Byum Hee, Marasa, Maddalena, Zhang, Jun Y., Na, Young-Ji, Lim, Tze Y., Ahram, Dina, Weng, Patricia L., Heinzen, Erin L., Carrea, Alba, Piaggio, Giorgio, Gesualdo, Loreto, Manca, Valeria, Masnata, Giuseppe, Gigante, Maddalena, Cusi, Daniele, Izzi, Claudia, Scolari, Francesco, van Wijk, Joanna A. E., Saraga, Marijan, Santoro, Domenico, Conti, Giovanni, Zamboli, Pasquale, White, Hope, Drozdz, Dorota, Zachwieja, Katarzyna, Miklaszewska, Monika, Tkaczyk, Marcin, Tomczyk, Daria, Krakowska, Anna, Sikora, Przemyslaw, Jarmoliński, Tomasz, Borszewska-Kornacka, Maria K., Pawluch, Robert, Szczepanska, Maria, Adamczyk, Piotr, Mizerska-Wasiak, Malgorzata, Krzemien, Grazyna, Szmigielska, Agnieszka, Zaniew, Marcin, Dobson, Mark G., Darlow, John M., Puri, Prem, Barton, David E., Furth, Susan L., Warady, Bradley A., Gucev, Zoran, Lozanovski, Vladimir J., Tasic, Velibor, Pisani, Isabella, Allegri, Landino, Rodas, Lida M., Campistol, Josep M., Jeanpierre, Cécile, Alam, Shumyle, Casale, Pasquale, Wong, Craig S., Lin, Fangming, Miranda, Débora M., Oliveira, Eduardo A., Simoes-e-Silva, Ana Cristina, Barasch, Jonathan M., Levy, Brynn, Wu, Nan, Hildebrandt, Friedhelm, Ghiggeri, Gian Marco, Latos-Bielenska, Anna, Materna-Kiryluk, Anna, Zhang, Feng, Hakonarson, Hakon, Papaioannou, Virginia E., Mendelsohn, Cathy L., Gharavi, Ali G., and Sanna-Cherchi, Simone

Published
2019
Full Text
View/download PDF

37. Right Heart Pulmonary Circulation Unit Response to Exercise in Patients with Controlled Systemic Arterial Hypertension: Insights from the RIGHT Heart International NETwork (RIGHT-NET)

Author

Vriz, Olga, primary, Palatini, Paolo, additional, Rudski, Lawrence, additional, Frumento, Paolo, additional, Kasprzak, Jarosław D., additional, Ferrara, Francesco, additional, Cocchia, Rosangela, additional, Gargani, Luna, additional, Wierzbowska-Drabik, Karina, additional, Capone, Valentina, additional, Ranieri, Brigida, additional, Salzano, Andrea, additional, Stanziola, Anna Agnese, additional, Marra, Alberto Maria, additional, Annunziata, Roberto, additional, Chianese, Salvatore, additional, Rega, Salvatore, additional, Saltalamacchia, Teresa, additional, Maramaldi, Renato, additional, Sepe, Chiara, additional, Limongelli, Giuseppe, additional, Cademartiri, Filippo, additional, D’Andrea, Antonello, additional, D’Alto, Michele, additional, Izzo, Raffaele, additional, Ferrara, Nicola, additional, Mauro, Ciro, additional, Cittadini, Antonio, additional, Ekkehard, Grünig, additional, Guazzi, Marco, additional, and Bossone, Eduardo, additional

Published
2022
Full Text
View/download PDF

38. Gene Abnormalities in Transplant Associated-Thrombotic Microangiopathy: Comparison between Recipient and Donor's DNA

Author

Rodrigues, Evangeline Millicent, additional, Ardissino, Gianluigi, additional, Pintarelli, Giulia, additional, Capone, Valentina, additional, Mariotti, Jacopo, additional, Verna, Marta, additional, Bernardo, Maria Ester, additional, Faraci, Maura, additional, Tozzi, Monica, additional, Bucalossi, Alessandro, additional, Schiavello, Elisabetta, additional, Biassoni, Veronica, additional, Guidetti, Anna, additional, Carotti, Alessandra, additional, Facchini, Luca, additional, Terruzzi, Elisabetta, additional, Giglio, Fabio, additional, Zecca, Marco, additional, Onida, Francesco, additional, Caroti, Leonardo, additional, Cesaro, Simone, additional, Consonni, Dario, additional, Cugno, Massimo, additional, and Porcaro, Luigi, additional

Published
2021
Full Text
View/download PDF

39. Reference Ranges of Left Ventricular Hemodynamic Forces in Healthy Adults: A Speckle-Tracking Echocardiographic Study

Author

Ferrara, Francesco, primary, Capuano, Francesco, additional, Cocchia, Rosangela, additional, Ranieri, Brigida, additional, Contaldi, Carla, additional, Lacava, Graziella, additional, Capone, Valentina, additional, Chianese, Salvatore, additional, Rega, Salvatore, additional, Annunziata, Roberto, additional, Sepe, Chiara, additional, Salzano, Andrea, additional, Citro, Rodolfo, additional, D’Andrea, Antonello, additional, Mauro, Ciro, additional, Cademartiri, Filippo, additional, Pedrizzetti, Gianni, additional, and Bossone, Eduardo, additional

Published
2021
Full Text
View/download PDF

40. Preoperative Assessment and Management of Cardiovascular Risk in Patients Undergoing Non-Cardiac Surgery: Implementing a Systematic Stepwise Approach during the COVID-19 Pandemic Era

Author

Bossone, Eduardo, primary, Cademartiri, Filippo, additional, AlSergani, Hani, additional, Chianese, Salvatore, additional, Mehta, Rahul, additional, Capone, Valentina, additional, Ruotolo, Carlo, additional, Tarrar, Imran Hayat, additional, Frangiosa, Antonio, additional, Vriz, Olga, additional, Maffei, Vincenzo, additional, Annunziata, Roberto, additional, Galzerano, Domenico, additional, Ranieri, Brigida, additional, Sepe, Chiara, additional, Salzano, Andrea, additional, Cocchia, Rosangela, additional, Majolo, Massimo, additional, Russo, Giuseppe, additional, Longo, Giuseppe, additional, Muto, Mario, additional, Fedelini, Paolo, additional, Esposito, Ciro, additional, Perrella, Alessandro, additional, Guggino, Gianluca, additional, Raiola, Eliana, additional, Catalano, Mara, additional, De Palma, Maurizio, additional, Romano, Luigia, additional, Romano, Gaetano, additional, Coppola, Ciro, additional, Mauro, Ciro, additional, and Mehta, Rajendra H., additional

Published
2021
Full Text
View/download PDF

41. Bloody Diarrhea and Shiga Toxin–Producing Escherichia coli Hemolytic Uremic Syndrome in Children: Data from the ItalKid-HUS Network

Author

Ardissino, Gianluigi, primary, Vignati, Chiara, additional, Masia, Carla, additional, Capone, Valentina, additional, Colombo, Rosaria, additional, Tel, Francesca, additional, Daprai, Laura, additional, Testa, Sara, additional, Dodaro, Antonella, additional, Paglialonga, Fabio, additional, Luini, Mario, additional, Brigotti, Maurizio, additional, Picicco, Damiano, additional, Baldioli, Carlo, additional, Pagani, Franca, additional, Ceruti, Rossella, additional, Tommasi, Paola, additional, Possenti, Ilaria, additional, Cresseri, Donata, additional, Consonni, Dario, additional, Montini, Giovanni, additional, and Arghittu, Milena, additional

Published
2021
Full Text
View/download PDF

42. Successful surgical repair of left ventricular pseudoaneurysm in a patient with subacute ST-elevation myocardial infarction

Author

Cocchia, Rosangela, primary, Iannelli, Gabriele, additional, Capone, Valentina, additional, Chianese, Salvatore, additional, Langella, Giuseppina, additional, Ranieri, Brigida, additional, Majolo, Massimo, additional, Russo, Giuseppe, additional, Pilato, Emanuele, additional, Mauro, Ciro, additional, and Bossone, Eduardo, additional

Published
2021
Full Text
View/download PDF

43. Fluid intake and blood pressure in children

Author

Ardissino, Gianluigi, primary, Perrone, Michela, additional, Ghiglia, Silvia, additional, Salice, Patrizia, additional, Tel, Francesca, additional, Dardi, Elena, additional, Bollani, Tiziana, additional, Mezzopane, Antonella, additional, Capone, Valentina, additional, Ardissino, Maddalena, additional, Vergori, Antonio, additional, Piantanida, Sandra, additional, Di Michele, Silvia, additional, Tchana, Bertrand, additional, Filippucci, Lucia, additional, De Luca, Francesco, additional, Consonni, Dario, additional, and Buzzetti, Roberto, additional

Published
2021
Full Text
View/download PDF

45. Multiple, random spot urine sampling for estimating urinary sodium excretion

Author

Ardissino, Gianluigi, primary, Vergori, Antonio, additional, Vergori, Cesare, additional, Martelli, Laura, additional, Daccò, Valeria, additional, Villa, Maria Cristina, additional, Masciani, Martino, additional, Monzani, Alice, additional, Salice, Patrizia, additional, Ghiglia, Silvia, additional, Perrone, Michela, additional, Capone, Valentina, additional, Mancuso, Maria Cristina, additional, Giussani, Antenore, additional, Pieri, Giovanni Raimondo, additional, Bosco, Annalisa, additional, Brambilla, Marta, additional, Romano, Roberto, additional, Rotondo, Stefania, additional, and Buzzetti, Roberto, additional

Published
2021
Full Text
View/download PDF

46. Calcium carbonate-enriched cheese to improve nutrition, compliance and phosphorus control in patients on kidney replacement therapy

Author

Ardissino, Gianluigi, primary, Matta, Roberto, additional, Patricelli, Mariagrazia, additional, Capone, Valentina, additional, Leoni, Antonio, additional, Groppelli, Antonio, additional, Vettoretti, Simone, additional, Pavone, Laura, additional, Margiotta, Elisabetta, additional, Brancadoro, Annamaria, additional, Grimaldi, Emanuele, additional, Cropanese, Isabella, additional, Raffiotta, Francesca, additional, Messa, Piergiorgio, additional, and Montini, Giovanni, additional

Published
2021
Full Text
View/download PDF

47. Gene Abnormalities in Transplant Associated-Thrombotic Microangiopathy: Comparison between Recipient and Donor's DNA.

Author

Rodrigues, Evangeline Millicent, Ardissino, Gianluigi, Pintarelli, Giulia, Capone, Valentina, Mariotti, Jacopo, Verna, Marta, Bernardo, Maria Ester, Faraci, Maura, Tozzi, Monica, Bucalossi, Alessandro, Schiavello, Elisabetta, Biassoni, Veronica, Guidetti, Anna, Carotti, Alessandra, Facchini, Luca, Terruzzi, Elisabetta, Giglio, Fabio, Zecca, Marco, Onida, Francesco, and Caroti, Leonardo

Published
2022
Full Text
View/download PDF

48. Cardiac teleconsulting in the time of COVID-19 global pandemic: The “Antonio Cardarelli” Hospital project

Author

Bossone, Eduardo, primary, Mauro, Ciro, additional, Maiellaro, Alfonso, additional, Raiola, Eliana, additional, Cocchia, Rosangela, additional, Ranieri, Brigida, additional, Sepe, Chiara, additional, Capone, Valentina, additional, Chianese, Salvatore, additional, Maramaldi, Renato, additional, Acerra, Enrico Pasquale, additional, Mirto, Gaetano, additional, Lodato, Sergio, additional, Russo, Giuseppe, additional, and Longo, Giuseppe, additional

Published
2021
Full Text
View/download PDF

49. The ANTENATAL multicentre study to predict postnatal renal outcome in fetuses with posterior urethral valves: objectives and design

Author

Buffin-Meyer, Bénédicte, Klein, Julie, van der Zanden, Loes F M, Levtchenko, Elena, Moulos, Panogiotis, Lounis, Nadia, Conte-Auriol, Françoise, Hindryckx, An, Wühl, Elke, Persico, Nicola, Oepkes, Dick, Schreuder, Michiel F, Tkaczyk, Marcin, Ariceta, Gema, Fossum, Magdalena, Parvex, Paloma, Feitz, Wout, Olsen, Henning, Montini, Giovanni, Decramer, Stéphane, Schanstra, Joost P, De Catte, Luc, Vayssieres, Christophe, Sartor, Agnès, Groussolles, Marion, Plard, Christelle, Guerby, Paul, Connan, Laure, Morin, Mathieu, Simon, Elizabeth, Breaud, Jean, Saliou, Anne-Hélène, De Parscau, Loic, Jay, Nadine, Germouty, Isabelle, Le Bouar, Gwenaelle, Ryckewaert, Amelie, Manca-Pellissier, Marie-Christine, Merrot, Thierry, Laurichesse, Helene, Gallot, Denis, Bessenay, Lucie, Bidat, Laurent, Boize, Philippe, Winer, Norbert, Allain-Launey, Emma, Le Vaillant, Claudine, Prieur, Fabienne, Lavocat, Marie-Pierre, Coatleven, Frederic, Debromez, Eric, Harembat, Jérôme, Llanas, Brigitte, Favre, Romain, Moog, Raphael, Zaloszyc, Ariane, Massardier, Jérôme, Demede, Delphine, Perrotin, Franck, Cloarec, Sylvie, Vequeau-Goua, Valérie, Descombes, Emmanuelle, Boulot, Pierre, Morin, Denis, Fuchs, Florent, Tenenbaum, Julie, Ville, Yves, Blanc, Thomas, Heidet, Laurence, Paris, Anne, Dobremez, Eric, Froute, Marie-Françoise, Gondry, Jean, Muszynski, Charles, Haraux, Elodie, Lobelle, Fabienne, Chevreau, Julien, Rosenblatt, Jonathan, Baudoin, Véronique, Deschenes, Georges, Guigue, Virginie, Amblard, Florence, Bourdat-Michel, Guylhène, Schaefer, Franz, Elsässer, Michael, Rossi, Federica, Manzoni, Gianantonio, De Marco, Erika A, Capone, Valentina, Caforio, Leonardo, Zaccara, Antonio, Innocenzi, Michele, Bagolan, Pietro, Capozza, Nicola, Castagnetti, Marco, Mancini, Mariangela, van Scheltema, Phebe Adama, Kortmann, Barbara, Schreuder, Michiel, Stańczyk, Małgorzata, Szaflik, Krzysztof, Wojtera, Justyna, Krzeszowski, Waldemar, Talar, Tomasz, Pawłowska, Barbara, Fortecka-Piestrzeniewicz, Katarzyna, Olejniczak, Dariusz, Arevalo, Silvia, Rodo, Carlota, Lindgren, Peter, Chehade, Hassib, ANTENATAL Consortium, Hindryckx, A., De Catte, L., Vayssieres, C., Sartor, A., Groussolles, M., Plard, C., Guerby, P., Connan, L., Morin, M., Simon, E., Breaud, J., Saliou, A.H., De Parscau, L., Jay, N., Germouty, I., Le Bouar, G., Ryckewaert, A., Manca-Pellissier, M.C., Merrot, T., Laurichesse, H., Gallot, D., Bessenay, L., Bidat, L., Boize, P., Winer, N., Allain-Launey, E., Le Vaillant, C., Prieur, F., Lavocat, M.P., Coatleven, F., Debromez, E., Harembat, J., Llanas, B., Favre, R., Moog, R., Zaloszyc, A., Massardier, J., Demede, D., Perrotin, F., Cloarec, S., Vequeau-Goua, V., Descombes, E., Boulot, P., Morin, D., Fuchs, F., Tenenbaum, J., Ville, Y., Blanc, T., Heidet, L., Paris, A., Dobremez, E., Froute, M.F., Gondry, J., Muszynski, C., Haraux, E., Lobelle, F., Chevreau, J., Rosenblatt, J., Baudoin, V., Deschenes, G., Guigue, V., Amblard, F., Bourdat-Michel, G., Wühl, E., Schaefer, F., Elsässer, M., Persico, N., Rossi, F., Manzoni, G., De Marco, E.A., Montini, G., Capone, V., Caforio, L., Zaccara, A., Innocenzi, M., Bagolan, P., Capozza, N., Castagnetti, M., Mancini, M., Oepkes, D., van Scheltema, P.A., Feitz, W., Kortmann, B., Schreuder, M., Tkaczyk, M., Stańczyk, M., Szaflik, K., Wojtera, J., Krzeszowski, W., Talar, T., Pawłowska, B., Fortecka-Piestrzeniewicz, K., Olejniczak, D., Ariceta, G., Arevalo, S., Rodo, C., Fossum, M., Lindgren, P., Parvex, P., Chehade, H., Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, Radboud University Medical Center [Nijmegen], Catholic University of Leuven - Katholieke Universiteit Leuven (KU Leuven), HybridStat Predictive Analytics [Athens, Greece], Centre d'investigation clinique de Toulouse (CIC 1436), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), University Hospitals Leuven [Leuven], Heidelberg University Hospital [Heidelberg], University of Milan, Fondazione IRCCS Ca’ Granda – Ospedale Maggiore Policlinico [Milan, Italy], Leiden University Medical Center (LUMC), Radboud Institute for Molecular Life Sciences [Nijmegen, the Netherlands], Polish Mother’s Memorial Hospital Research Institute [Lodz] (ICZMP), Pediatric Nephrology [Barcelona, Spain] (Vall d’Hebron Hospital), Universitat Autònoma de Barcelona (UAB)-Vall d'Hebron University Hospital [Barcelona], Karolinska University Hospital [Stockholm], Karolinska Institutet [Stockholm], Geneva University Hospital (HUG), Aarhus University Hospital, Aarhus University [Aarhus], Fondazione IRCCS Ca' Granda - Ospedale Maggiore Policlinico, ANTENATAL Consortium: An Hindryckx, Luc De Catte, Christophe Vayssieres, Agnès Sartor, Marion Groussolles, Christelle Plard, Paul Guerby, Laure Connan, Mathieu Morin, Elizabeth Simon, Jean Breaud, Anne-Hélène Saliou, Loic De Parscau, Nadine Jay, Isabelle Germouty, Gwenaelle Le Bouar, Amelie Ryckewaert, Marie-Christine Manca-Pellissier, Thierry Merrot, Helene Laurichesse, Denis Gallot, Lucie Bessenay, Laurent Bidat, Philippe Boize, Norbert Winer, Emma Allain-Launey, Claudine Le Vaillant, Fabienne Prieur, Marie-Pierre Lavocat, Frederic Coatleven, Eric Debromez, Jérôme Harembat, Brigitte Llanas, Romain Favre, Raphael Moog, Ariane Zaloszyc, Jérôme Massardier, Delphine Demede, Franck Perrotin, Sylvie Cloarec, Valérie Vequeau-Goua, Emmanuelle Descombes, Pierre Boulot, Denis Morin, Florent Fuchs, Julie Tenenbaum, Yves Ville, Thomas Blanc, Laurence Heidet, Anne Paris, Eric Dobremez, Marie-Françoise Froute, Jean Gondry, Charles Muszynski, Elodie Haraux, Fabienne Lobelle, Julien Chevreau, Jonathan Rosenblatt, Véronique Baudoin, Georges Deschenes, Virginie Guigue, Florence Amblard, Guylhène Bourdat-Michel, Elke Wühl, Franz Schaefer, Michael Elsässer, Nicola Persico, Federica Rossi, Gianantonio Manzoni, Erika A De Marco, Giovanni Montini, Valentina Capone, Leonardo Caforio, Antonio Zaccara, Michele Innocenzi, Pietro Bagolan, Nicola Capozza, Marco Castagnetti, Mariangela Mancini, Dick Oepkes, Phebe Adama van Scheltema, Wout Feitz, Barbara Kortmann, Michiel Schreuder, Marcin Tkaczyk, Małgorzata Stańczyk, Krzysztof Szaflik, Justyna Wojtera, Waldemar Krzeszowski, Tomasz Talar, Barbara Pawłowska, Katarzyna Fortecka-Piestrzeniewicz, Dariusz Olejniczak, Gema Ariceta, Silvia Arevalo, Carlota Rodo, Magdalena Fossum, Peter Lindgren, Paloma Parvex, Hassib Chehade., Schanstra, Joost, Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Pôle Santé publique et médecine publique [CHU Toulouse], Centre Hospitalier Universitaire de Toulouse (CHU Toulouse)-Centre Hospitalier Universitaire de Toulouse (CHU Toulouse), and Università degli Studi di Milano = University of Milan (UNIMI)

Subjects
Posterior urethral valve, medicine.medical_specialty, Urinary system, [SDV]Life Sciences [q-bio], kidney disease, prenatal biomarkers, Renal function, Prenatal care, 030204 cardiovascular system & hematology, DIAGNOSIS, 03 medical and health sciences, All institutes and research themes of the Radboud University Medical Center, 0302 clinical medicine, Medicine, obstructive uropathy, Obstructive uropathy, development, 030304 developmental biology, RISK, 0303 health sciences, Transplantation, Kidney, ddc:618, Science & Technology, business.industry, Obstetrics, Original Articles, prediction, Urology & Nephrology, Omics, medicine.disease, 6. Clean water, 3. Good health, [SDV] Life Sciences [q-bio], Reconstructive and regenerative medicine Radboud Institute for Molecular Life Sciences [Radboudumc 10], Renal disorders Radboud Institute for Molecular Life Sciences [Radboudumc 11], medicine.anatomical_structure, Nephrology, embryonic structures, Settore MED/20, URINARY-TRACT OBSTRUCTION, Renal disorders Radboud Institute for Health Sciences [Radboudumc 11], business, Life Sciences & Biomedicine, Kidney disease
Abstract

Altres ajuts: The study is partially made possible by support of the 'Programme Hospitalier de Recherche Clinique and 'La Foundation de la Recherche Médicale (grant number DEQ20170336759, France). M.T. was supported by the Polish Mothers Memorial Hospital Research Institute (internal grant number 2016/IV/54-GW. LvdZ is supported by a Kolff grant from the Dutch Kidney Foundation (13OKJ36) and a ZonMW-VENI grant from the Netherlands Organisation for Scientific Research (91618036). This project has been supported by ERN ERKNet and ERN eUROGEN, which are partly co-funded by the European Union within the framework of the Third Health Programme 'ERN-2016-Framework Partnership Agreement 2017-2021'. Posterior urethral valves (PUV) account for 17% of paediatric end-stage renal disease. A major issue in the management of PUV is prenatal prediction of postnatal renal function. Fetal ultrasound and fetal urine biochemistry are currently employed for this prediction, but clearly lack precision. We previously developed a fetal urine peptide signature that predicted in utero with high precision postnatal renal function in fetuses with PUV. We describe here the objectives and design of the prospective international multicentre ANTENATAL (multicentre validation of a fetal urine peptidome-based classifier to predict postnatal renal function in posterior urethral valves) study, set up to validate this fetal urine peptide signature. Participants will be PUV pregnancies enrolled from 2017 to 2021 and followed up until 2023 in >30 European centres endorsed and supported by European reference networks for rare urological disorders (ERN eUROGEN) and rare kidney diseases (ERN ERKNet). The endpoint will be renal/patient survival at 2 years postnatally. Assuming α = 0.05, 1-β = 0.8 and a mean prevalence of severe renal outcome in PUV individuals of 0.35, 400 patients need to be enrolled to validate the previously reported sensitivity and specificity of the peptide signature. In this largest multicentre study of antenatally detected PUV, we anticipate bringing a novel tool to the clinic. Based on urinary peptides and potentially amended in the future with additional omics traits, this tool will be able to precisely quantify postnatal renal survival in PUV pregnancies. The main limitation of the employed approach is the need for specialized equipment. Accurate risk assessment in the prenatal period should strongly improve the management of fetuses with PUV.

Published
2020
Full Text
View/download PDF

50. Corrigendum to “The long-acting C5 inhibitor, ravulizumab, is effective and safe in pediatric patients with atypical hemolytic uremic syndrome naïve to complement inhibitor treatment.” Kidney Int. 2021;100:225–237

Author

Lovell, Helen, Muff-Luett, Melissa, Malone, Kristin, Adeagbo, Oluwasegun, Wilkerson, Alexandria, Fraga, Gloria, Sarri, Scherezade, Cheong, Hae Il, Ahn, Yo Han, Han, Kyoung Hee, Wühl, Elke, Ardissino, Gianluigi, Capone, Valentina, Constantinescu, Alexandru, Boydstun, Ivy, Raafat, Reem, Mersha, Marezhe, Wandique-Rapalo, Belkis, Hataya, Hiroshi, Hamada, Terano, Rees, Lesley, Pose, Araceli Garcia, Pérez, Inés Vergara, Vilariño, Mercedes Cao, Adams, Brigitte, Nathalie, Tram, Ariceta, Gema, Dixon, Bradley P., Kim, Seong Heon, Kapur, Gaurav, Mauch, Teri, Ortiz, Stephan, Vallee, Marc, Denker, Andrew E., Kang, Hee Gyung, and Greenbaum, Larry A.

Published
2023
Full Text
View/download PDF

Catalog

Books, media, physical & digital resources
See catalog results