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2. Contributors

Author

Adler, Amanda I., primary, Arnal, Emma, additional, Arora, Vipin, additional, Arrick, Denise M., additional, Arumugam, Somasundaram, additional, Balestrieri, Maria Luisa, additional, Basu, Arpita, additional, Brasnyó, Pál, additional, Bryant, Alecia L., additional, Capoluongo, Maria Carmela, additional, Cazzola, Roberta, additional, Cestaro, Benvenuto, additional, Chopra, Kanwaljit, additional, Cukurova, Zafer, additional, D’Onofrio, Nunzia, additional, Das, Joydeep, additional, Dave, Kunjan R., additional, del-Rio-Vellosillo, Monica, additional, Dharmalingam, Mala, additional, Eren, Gulay, additional, Fuchs, Perry, additional, Gallego-Pinazo, Roberto, additional, Garcia-Medina, Jose Javier, additional, Garcia-Medina, Manuel, additional, Goldenstein, Hagit, additional, Hergunsel, Oya, additional, Hou, Yu-Chen, additional, Johnsen-Soriano, Siv, additional, Karuppagounder, Vengadeshprabhu, additional, Kim, Sung-Jin, additional, Kuhad, Anurag, additional, Lee, Christine, additional, Levy, Andrew P., additional, Lim, Soo, additional, Luzia, Liania Alves, additional, Lyons, Timothy J., additional, Marcus, Sara Rani, additional, Marfella, Raffaele, additional, Mayhan, William G., additional, Miranda, María, additional, Murrow, Jonathan R., additional, Neyestani, Tirang R., additional, Ozawa, Yoko, additional, Paolisso, Giuseppe, additional, Park, Yongsoo, additional, Park, Kyong Soo, additional, Patel, Vinood B., additional, Perez-Pinzon, Miguel A., additional, Pinazo-Duran, Maria Dolores, additional, Pitchaimani, Vigneshwaran, additional, Qian, Qingwen, additional, Qian, Shuhong, additional, Rizzo, Maria Rosaria, additional, Romero, Francisco J., additional, Rondo, Patricia Helen, additional, Sasaki, Mariko, additional, Servillo, Luigi, additional, Sil, Parames C., additional, Sirangelo, Ivana, additional, Sone, Hirohito, additional, Sümegi, Balázs, additional, Thandavarayan, Rajarajan A., additional, Victor, Victor M., additional, Ward, John, additional, Watanabe, Kenichi, additional, Winkler, Gábor, additional, Wittmann, István, additional, Yeh, Sung-Ling, additional, and Zanon-Moreno, Vicente, additional

Published
2014
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4. Polyphenols, Oxidative Stress, and Vascular Damage in Diabetes

Author

MARFELLA, Raffaele, D'Onofrio, Nunzia, SIRANGELO, Ivana, RIZZO, Maria Rosaria, Capoluongo, Maria Carmela, SERVILLO, Luigi, PAOLISSO, Giuseppe, BALESTRIERI, Maria Luisa, D'ONOFRIO, NUNZIA, Several Authors, Victor R. Preedy, Marfella, Raffaele, D'Onofrio, Nunzia, Sirangelo, Ivana, Rizzo, Maria Rosaria, Capoluongo, Maria Carmela, Servillo, Luigi, Paolisso, Giuseppe, and Balestrieri, Maria Luisa

Subjects
Polyphenol, Diabetes risk, Medicine (miscellaneous), food and beverages, Nitric oxide, Vascular damage, Biology, Carbohydrate metabolism, Pharmacology, medicine.disease, medicine.disease_cause, Endothelial progenitor cell, chemistry.chemical_compound, chemistry, Biochemistry, Diabetes mellitus, medicine, Oxidative stre, Soy milk, Oxidative stress
Abstract

Oxidative stress induced by hyperglycemia is a key factor in the development and progression of diabetes and its vascular complications. Dietary polyphenols have received enormous attention because their consumption has been associated with lower rates of diabetes and cardiovascular diseases. These compounds are of plant origin, and are abundant in fruit, vegetables, chocolate, and nuts, as well as in beverages such as tea, coffee, wine, and soy milk. They can be divided into at least ten separate classes, four of which are important in the human diet: phenolic acids, flavonoids, stilbenes, and lignans. A number of in vitro and in vivo studies support the effect of polyphenols on glucose metabolism, diabetes risk, and diabetic impairments in the nitric oxide-mediated endothelial progenitor cell mobilization and homing. This chapter intends to review the current knowledge on polyphenols, oxidative stress, and vascular damage in diabetes, focusing on the most important and recent advances and challenges for future research.

Published
2014

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