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1. Autocrine PDGFR signaling promotes mammary cancer metastasis

Author

Jechlinger, Martin, Sommer, Andreas, Moriggl, Richard, Seither, Peter, Kraut, Norbert, Capodiecci, Paola, Donovan, Michael, Cordon-Cardo, Carlos, Beug, Hartmut, and Grunert, Stefan

Subjects
Breast cancer -- Research, Breast cancer -- Drug therapy, Metastasis -- Research, Medical research, Medicine, Experimental
Abstract

Metastasis is the major cause of cancer morbidity, but strategies for direct interference with invasion processes are lacking. Dedifferentiated, late-stage tumor cells secrete multiple factors that represent attractive targets for [...]

Published
2006

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