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3. Predictors of three-month mortality and severe chemotherapy-related adverse events in patients aged 70 years and older with metastatic non-small-cell lung cancer: A secondary analysis of ESOGIA-GFPC-GECP 08–02 study

Author

Gendarme, Sébastien, Zebachi, Sonia, Corre, Romain, Greillier, Laurent, Justeau, Grégoire, Bylicki, Olivier, Decroisette, Chantal, Auliac, Jean-Bernard, Guisier, Florian, Geier, Margaux, Ricordel, Charles, Frelaut, Maxime, Paillaud, Elena, Chouaïd, Christos, and Canouï-Poitrine, Florence

Published
2024
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10. SARS-CoV-2 Omicron BA.1 breakthrough infection drives late remodeling of the memory B cell repertoire in vaccinated individuals

Author

Sokal, Aurélien, Barba-Spaeth, Giovanna, Hunault, Lise, Fernández, Ignacio, Broketa, Matteo, Meola, Annalisa, Fourati, Slim, Azzaoui, Imane, Vandenberghe, Alexis, Lagouge-Roussey, Pauline, Broutin, Manon, Roeser, Anais, Bouvier-Alias, Magali, Crickx, Etienne, Languille, Laetitia, Fournier, Morgane, Michel, Marc, Godeau, Bertrand, Gallien, Sébastien, Melica, Giovanna, Nguyen, Yann, Canoui-Poitrine, Florence, Pirenne, France, Megret, Jérôme, Pawlotsky, Jean-Michel, Fillatreau, Simon, Reynaud, Claude-Agnès, Weill, Jean-Claude, Rey, Félix A., Bruhns, Pierre, Mahévas, Matthieu, and Chappert, Pascal

Published
2023
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12. Prolonged response after TPO-RA discontinuation in primary ITP: results of a prospective multicenter study

Author

Guillet, Stéphanie, Crickx, Etienne, Azzaoui, Imane, Chappert, Pascal, Boutin, Emmanuelle, Viallard, Jean-François, Rivière, Etienne, Gobert, Delphine, Galicier, Lionel, Malphettes, Marion, Cheze, Stéphane, Lefrere, François, Audia, Sylvain, Bonnotte, Bernard, Lambotte, Olivier, Noel, Nicolas, Fain, Olivier, Moulis, Guillaume, Hamidou, Mohamed, Gerfaud-Valentin, Mathieu, Marolleau, Jean-Pierre, Terriou, Louis, Martis, Nihal, Morin, Anne-Sophie, Perlat, Antoinette, Le Gallou, Thomas, Roy-Peaud, Frédérique, Robbins, Ailsa, Lega, Jean-Christophe, Puyade, Matthieu, Comont, Thibault, Limal, Nicolas, Languille, Laetitia, Zarrour, Anissa, Luka, Marine, Menager, Mickael, Belmondo, Thibault, Hue, Sophie, Canoui-Poitrine, Florence, Michel, Marc, Godeau, Bertrand, and Mahévas, Matthieu

Published
2023
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15. Immune thrombocytopenia and pregnancy: an exposed/nonexposed cohort study

Author

Guillet, Stéphanie, Loustau, Valentine, Boutin, Emmanuelle, Zarour, Anissa, Comont, Thibault, Souchaud-Debouverie, Odile, Costedoat Chalumeau, Nathalie, Pan-Petesch, Brigitte, Gobert, Delphine, Cheze, Stéphane, Viallard, Jean Francois, Morin, Anne-Sophie, Sauvetre, Gaetan, Cliquennois, Manuel, Royer, Bruno, Masseau, Agathe, Terriou, Louis, Fieschi, Claire, Lambotte, Olivier, Girault, Stéphane, Lioger, Bertrand, Audia, Sylvain, Sacre, Karim, Lega, Jean Christophe, Langlois, Vincent, Benachi, Alexandra, Orvain, Corentin, Devidas, Alain, Humbert, Sebastien, Gambier, Nicolas, Ruivard, Marc, Zarrouk, Virginie, Ebbo, Mikael, Willems, Lise, Segaux, Lauriane, Mahevas, Matthieu, Haddad, Bassam, Michel, Marc, Canoui-Poitrine, Florence, and Godeau, Bertrand

Published
2023
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16. Changes in amyloidosis phenotype over 11 years in a cardiac amyloidosis referral centre cohort in France

Author

Damy, Thibaud, Zaroui, Amira, de Tournemire, Marie, Kharoubi, Mounira, Gounot, Romain, Galat, Arnault, Guendouz, Soulef, Funalot, Benoit, Itti, Emmanuel, Roulin, Louise, Audard, Vincent, Fanen, Pascale, Leroy, Vincent, Poulot, Elsa, Belhadj, Karim, Mallet, Sophie, Deep Singh Chadah, Gagan, Planté-Bordeneuve, Violaine, Gendre, Thierry, Chevalier, Xavier, Guignard, Sandra, Bequignon, Emilie, Bartier, Sophie, Folliguet, Thierry, Lemonier, François, Audureau, Etienne, Tixier, Denis, Canoui-Poitrine, Florence, Lefaucheur, Jean-Pascal, Souvannanorath, Sarah, Authier, Francois-Jerome, Maupou, Steven, Hittinger, Luc, Molinier-Frenkel, Valérie, David, Jean-Philippe, Broussier, Amaury, Oghina, Silvia, and Teiger, Emmanuel

Published
2023
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22. Epidemiology of Colorectal Cancer: Incidence, Survival, and Risk Factors

Author

Canouï-Poitrine, Florence, Martinez-Tapia, Claudia, Guittet, Lydia, Bouvier, Anne-Marie, Coccolini, Federico, Series Editor, Coimbra, Raul, Series Editor, Kirkpatrick, Andrew W., Series Editor, Di Saverio, Salomone, Series Editor, Ansaloni, Luca, Editorial Board Member, Balogh, Zsolt, Editorial Board Member, Biffl, Walt, Editorial Board Member, Catena, Fausto, Editorial Board Member, Davis, Kimberly, Editorial Board Member, Ferrada, Paula, Editorial Board Member, Fraga, Gustavo, Editorial Board Member, Ivatury, Rao, Editorial Board Member, Kluger, Yoram, Editorial Board Member, Leppaniemi, Ari, Editorial Board Member, Maier, Ron, Editorial Board Member, E. Moore, Ernest, Editorial Board Member, Napolitano, Lena, Editorial Board Member, Peitzman, Andrew, Editorial Board Member, Rielly, Patrick, Editorial Board Member, Rizoli, Sandro, Editorial Board Member, Sakakushev, Boris, Editorial Board Member, Sartelli, Massimo, Editorial Board Member, Scalea, Thomas, Editorial Board Member, Spain, David, Editorial Board Member, Stahel, Philip, Editorial Board Member, Sugrue, Michael, Editorial Board Member, Velmahos, George, Editorial Board Member, Weber, Dieter, Editorial Board Member, de'Angelis, Nicola, editor, and Brunetti, Francesco, editor

Published
2019
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25. Hospital Care Trajectories of Older Adults with Cancer and the Associated Clinical Profiles: linking a French Prospective Cohort Study and a Clinical Data Warehouse

Author

Jean, Charline, primary, Paillaud, Elena, additional, Boudou-Rouquette, Pascaline, additional, Martinez-Tapia, Claudia, additional, Pamoukdjian, Frédéric, additional, Hagège, Meoïn, additional, Bréant, Stéphane, additional, Hassen-Khodja, Claire, additional, Natella, Pierre-André, additional, Cudennec, Tristan, additional, Laurent, Marie, additional, Caillet, Philippe, additional, Audureau, Etienne, additional, and Canouï-Poitrine, Florence, additional

Published
2024
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26. Disentangling the reasons why older adults do not readily participate in cancer trials: a socio-epidemiological mixed methods approach

Author

Hagège, Meoïn, primary, Bringuier, Michaël, additional, Martinez-Tapia, Claudia, additional, Chouaïd, Christos, additional, Helissey, Carole, additional, Brain, Etienne, additional, Lempdes, Godelieve Rochette, additional, Dubot, Coraline, additional, Bello-Roufai, Diana, additional, Geiss, Romain, additional, Kempf, Emmanuelle, additional, Gourden, Audrey, additional, Elgharbi, Hanane, additional, Garrigou, Sonia, additional, Gregoire, Laetitia, additional, Derbez, Benjamin, additional, and Canouï-Poitrine, Florence, additional

Published
2024
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28. Revue systématique du bilan carbone des interventions chirurgicales

Author

de’Angelis, Nicola, primary, Conso, Christel, additional, Bianchi, Giorgio, additional, Barría Rodríguez, Ana Gabriela, additional, Marchegiani, Francesco, additional, Carra, Maria Clotilde, additional, Lafont, Charlotte, additional, Canouï-Poitrine, Florence, additional, Slim, Karem, additional, and Pessaux, Patrick, additional

Published
2023
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29. Systematic review of carbon footprint of surgical procedures

Author

de’Angelis, Nicola, primary, Conso, Christel, additional, Bianchi, Giorgio, additional, Rodríguez, Ana Gabriela Barría, additional, Marchegiani, Francesco, additional, Carra, Maria Clotilde, additional, Lafont, Charlotte, additional, Canouï-Poitrine, Florence, additional, Slim, Karem, additional, and Pessaux, Patrick, additional

Published
2023
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30. Glomerular Filtration Rate Measured Based on Iomeprol Clearance Assessed at CT Urography in Living Kidney Donor Candidates

Author

Stehlé, Thomas, primary, Wei, Félix, additional, Brabant, Séverine, additional, Luciani, Alain, additional, Grimbert, Philippe, additional, Prié, Dominique, additional, Reizine, Edouard, additional, Durrbach, Antoine, additional, Mulé, Sébastien, additional, Hulin, Anne, additional, Boueilh, Anna, additional, Blain, Maxime, additional, Champy, Cécile-Maud, additional, Ingels, Alexandre, additional, Matignon, Marie, additional, Brasseur, Paul, additional, Canouï-Poitrine, Florence, additional, and Pigneur, Frédéric, additional

Published
2023
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35. Geriatric assessment and quality of life for 2 years in older patients with head and neck cancer.

Author

Lafont, Charlotte, Paillaud, Elena, Bertolus, Chloe, Baron, Melany, Caillet, Philippe, Bouvard, Eric, Laurent, Marie, Salvan, Didier, Chaumette, Laurence, Decker, Laure de, Piot, Benoit, Barry, Beatrix, Raynaud-Simon, Agathe, Sauvaget, Elisabeth, Minard, Aurélien, Anota, Amélie, Panjo, Henri, Brugel, Lydia, and Canouï-Poitrine, Florence

Subjects
HEAD & neck cancer, OLDER patients, GERIATRIC assessment, QUALITY of life, FUNCTIONAL status
Abstract

Due to the location and toxicity of treatments, head and neck cancer (HNC) has a major impact on quality of life (QoL). Objective: to assess the effects of geriatric-assessment (GA)-driven interventions on QoL over 2 years in older adults with HNC. EGeSOR was a randomized study of HNC patients aged ≥65, receiving a pretreatment GA, a geriatric intervention and follow-up (intervention) or standard of care (control). The primary endpoint was QoL score using the European Organisation for Research and Treatment of Cancer's (EORTC QLQ-C30) and HNC (QLQ-HN35) QoL questionnaires over 24 months. In total, 475 patients were included (median age: 75.3; women: 31%; oral cancer: 44%). QoL scores improved over 24 months with various trajectories, without significant differences between the groups. A total of 74% of patients (interventional group) did not receive the complete intervention. Cancer characteristics, functional status, and risk of frailty were associated with change in the Global Health Status QoL score. There is a need to develop an alternative model of implementation such as patient-centered health-care pathways. Trial registration NCT02025062. [ABSTRACT FROM AUTHOR]

Published
2024
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36. Systematic review of carbon footprint of surgical procedures.

Author

de'Angelis, Nicola, Conso, Christel, Bianchi, Giorgio, Rodríguez, Ana Gabriela Barría, Marchegiani, Francesco, Carra, Maria Clotilde, Lafont, Charlotte, Canouï-Poitrine, Florence, Slim, Karem, and Pessaux, Patrick

Subjects
OPERATIVE surgery, ECOLOGICAL impact, GREENHOUSE gases, SUSTAINABILITY, INHALATION anesthetics, GYNECOLOGIC surgery
Abstract

The ecological sustainability of the operating room (OR) is a matter of recent interest. The present systematic review aimed to review the current literature assessing the carbon footprint of surgical procedures in different surgical fields. Following to the PRISMA statement checklist, three databases (MEDLINE, EMBASE, Cochrane Library) were searched by independent reviewers, who screened records on title and abstract first, and then on the full text. Risk of bias was evaluated using the MINORS system. Over the 878 articles initially identified, 36 original studies were included. They considered ophthalmologic surgical procedures (30.5%), general/digestive surgery (19.4%), gynecologic procedures (13.9%), orthopedic procedures (8.3%), neurosurgery (5.5%), otolaryngology/head and neck surgery (5.5%), plastic/dermatological surgery (5.5%), and cardiac surgery (2.8%). Despite a great methodological heterogeneity, data showed that a single surgical procedure emits 4–814 kgCO2e, with anesthetic gases and energy consumption representing the largest sources of greenhouse gas emission. Minimally invasive surgical techniques may require more resources than conventional open surgery, particularly for packaging and plastics, energy use, and waste production. Each OR has the potential to produce from 0.2 to 4 kg of waste per case with substantial differences depending on the type of intervention, hospital setting, and geographic area. Overall, the selected studies were found to be of moderate quality. Based on a qualitative synthesis of the available literature, the OR can be targeted by programs and protocols implemented to reduce the carbon footprint and improve the waste stream of the OR. [ABSTRACT FROM AUTHOR]

Published
2024
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37. The Prognostic Value of Olfactory Dysfunction in Patients with COVID-19: The COVIDORA Study.

Author

Hamel, Anne-Laure, Delbos, Léo, Natella, Pierre-André, Radulesco, Thomas, Alexandru, Mihaela, Bartaire, Emmanuel, Bartier, Sophie, Benoite, Gonda, Bequignon, Emilie, Castillo, Laurent, Canouï-Poitrine, Florence, Carsuzaa, Florent, Corré, Alain, Coste, André, Couloigner, Vincent, Daveau, Clémentine, De Boissieu, Paul, De Bonnecaze, Guillaume, De Gabory, Ludovic, and Debry, Christian

Subjects
COVID-19, PROGNOSIS, SMELL disorders, PUBLIC hospitals, HOSPITAL admission & discharge
Abstract

Background: Among all studies describing COVID-19 clinical features during the first wave of the pandemic, only a few retrospective studies have assessed the correlation between olfac-tory dysfunction (OD) and the evolution of disease severity. The main aim was to assess whether OD is a predictive factor of COVID-19 severity based on the patient's medical management (outpa-tient care, standard hospital admission, and ICU admission). Methods: A national, prospective, mul-ticenter cohort study was conducted in 20 public hospitals and a public center for COVID-19 screen-ing. During the first wave of the pandemic, from 6 April to 11 May 2020, all patients tested positive for COVID-19 confirmed by RT-PCR underwent two follow-up ENT consultations within 10 days of symptom onset. The main outcome measures were the evolution of medical management (out-patient care, standard hospital admission, and ICU admission) at diagnosis and along the clinical course of COVID-19 disease. Results: Among 481 patients included, the prevalence of OD was 60.7%, and it affected mostly female patients (74.3%) under 65 years old (92.5%), with fewer comor-bidities than patients with normal olfactory function. Here, 99.3% (290/292) of patients with OD presented with non-severe COVID-19 disease. Patients reporting OD were significantly less hospi-talized than the ones managed as outpatients, in either a standard medical unit or an ICU. Conclu-sions: As regards the clinical course of COVID-19 disease, OD could predict a decreased risk of hospitalization during the first wave of the pandemic. [ABSTRACT FROM AUTHOR]

Published
2024
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38. Cancer mortality and competing causes of death in older adults with cancer: A prospective, multicentre cohort study (ELCAPA‐19)

Author

Assouan, Déborah, primary, Paillaud, Elena, additional, Caillet, Philippe, additional, Broussier, Amaury, additional, Kempf, Emmanuelle, additional, Frelaut, Maxime, additional, Brain, Etienne, additional, Lorisson, Emmanuelle, additional, Chambraud, Clelia, additional, Bastuji‐Garin, Sylvie, additional, Hanon, Olivier, additional, Canouï‐Poitrine, Florence, additional, Laurent, Marie, additional, and Martinez‐Tapia, Claudia, additional

Published
2023
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39. Exercise Interventions With Trained Home Helpers for Preventing Loss of Autonomy and Falls in Community-Dwelling Older Adults Receiving Home Heath Physical Therapy T4H: A Randomized Controlled Pilot Study

Author

Mézière, Anthony, Oubaya, Nadia, Michel-Pellegrino, Valérie, Boudin, Bertrand, Neau, Marine, Robert, Hervé, Cara, Isabelle, Salgado Sanchez, Laura, Baloul, Samia, Piette, François, Pautas, Eric, Picou, Yannick, Curtis, Valentine, Schonheit, Claire, Canouï-Poitrine, Florence, and Moreau, Caroline

Published
2021
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42. Prognostic value of the G8 and modified-G8 screening tools for multidimensional health problems in older patients with cancer

Author

Caillet, P., Laurent, M., Paillaud, E., Tournigand, C., Lagrange, J.-L., Canouï-Poitrine, F., Bastuji-Garin, S., Audureau, E., Natella, P.A., Segaux, L., Reinald, N., Allain, M., Ibrahim, R., Raccah, S., Martinez-Tapia, Claudia, Paillaud, Elena, Liuu, Evelyne, Tournigand, Christophe, Ibrahim, Rima, Fossey-Diaz, Virginie, Culine, Stéphane, Canoui-Poitrine, Florence, and Audureau, Etienne

Published
2017
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45. Predictors of three-month mortality and severe chemotherapy-related adverse events in patients aged 70 years and older with metastatic non-small-cell lung cancer: A secondary analysis of ESOGIA-GFPC-GECP 08–02 study

Author

Gendarme, Sébastien, primary, Zebachi, Sonia, additional, Corre, Romain, additional, Greillier, Laurent, additional, Justeau, Grégoire, additional, Bylicki, Olivier, additional, Decroisette, Chantal, additional, Auliac, Jean-Bernard, additional, Guisier, Florian, additional, Geier, Margaux, additional, Ricordel, Charles, additional, Frelaut, Maxime, additional, Paillaud, Elena, additional, Chouaïd, Christos, additional, and Canouï-Poitrine, Florence, additional

Published
2023
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48. Impact of the First COVID-19 Pandemic Wave on Hospitalizations and Deaths Caused by Geriatric Syndromes in France: A Nationwide Study.

Author

Torres, Marion J, Coste, Joël, Canouï-Poitrine, Florence, Pouchot, Jacques, Rachas, Antoine, and Carcaillon-Bentata, Laure

Subjects
COVID-19 pandemic, FEMORAL neck fractures, PRESSURE ulcers, COVID-19, HIP fractures, DELIRIUM, SYNDROMES, HOSPITAL care
Abstract

Background The fear of contracting coronavirus disease 2019 (COVID-19) and the preventive measures taken during the health crisis affected both people's lifestyles and the health system. This nationwide study aimed to investigate the impact of the first wave of the COVID-19 pandemic on hospitalizations and mortality related to geriatric syndromes (GS) in older adults in France. Methods The French National Health Data System was used to compare hospital admissions (excluding the main diagnosis of COVID-19) and mortality rates (using multiple-cause and initial-cause analyses, and both including or excluding confirmed/probable COVID-19) related to 10 different GS (dementia, other cognitive disorders and symptoms, delirium/disorientation, depression, undernutrition/malnutrition, dehydration, pressure ulcer, incontinence, fall/injury and femoral neck fracture) from January to September 2020 to rates observed in previous years. Analyses were stratified by age, sex, place of residence or place of death, and region. Results Hospitalization rates for all GS decreased during the first lockdown compared to the same periods in 2017-19 (from −59% for incontinence to −13% for femoral neck fractures). A dose–response relationship was observed between reduced hospitalizations and COVID-19-related mortality rates. Conversely, for almost all GS studied, excess mortality without COVID-19 was observed during this lockdown compared to 2015-17 (from +74% for delirium/disorientation to +8% for fall/injury), especially in nursing homes and at home. Conclusions In France, during the first lockdown, a substantial decrease in hospitalizations for GS was accompanied by excess mortality. This decline in the use of services, which persisted beyond lockdown, may have a mid- and long-term impact on older adults' health. [ABSTRACT FROM AUTHOR]

Published
2023
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49. A Two-Step Frailty Assessment Strategy in Older Patients With Solid Tumors: A Decision Curve Analysis

Author

González Serrano, Adolfo, primary, Laurent, Marie, additional, Barnay, Thomas, additional, Martínez-Tapia, Claudia, additional, Audureau, Etienne, additional, Boudou-Rouquette, Pascaline, additional, Aparicio, Thomas, additional, Rollot-Trad, Florence, additional, Soubeyran, Pierre, additional, Bellera, Carine, additional, Caillet, Philippe, additional, Paillaud, Elena, additional, and Canouï-Poitrine, Florence, additional

Published
2023
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50. Development and validation of a new equation based on plasma creatinine and muscle mass assessed by CT-scan to estimate glomerular filtration rate: a cross-sectional study

Author

Stehlé, Thomas, primary, Ouamri, Yaniss, additional, Morel, Antoine, additional, Vidal-Petiot, Emmanuelle, additional, Fellahi, Soraya, additional, Segaux, Lauriane, additional, Prié, Dominique, additional, Grimbert, Philippe, additional, Luciani, Alain, additional, Audard, Vincent, additional, Haymann, Jean Philippe, additional, Mulé, Sébastien, additional, De Kerviler, Eric, additional, Peraldi, Marie-Noëlle, additional, Boutten, Anne, additional, Matignon, Marie, additional, Canouï-Poitrine, Florence, additional, Flamant, Martin, additional, and Pigneur, Frédéric, additional

Published
2023
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