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15 results on '"Cannas, Alessandra"'

1. A Genome-Wide Association Study of Depressive Symptoms

Author

Hek, Karin, Demirkan, Ayse, Lahti, Jari, Terracciano, Antonio, Teumer, Alexander, Cornelis, Marilyn C, Amin, Najaf, Bakshis, Erin, Baumert, Jens, Ding, Jingzhong, Liu, Yongmei, Marciante, Kristin, Meirelles, Osorio, Nalls, Michael A, Sun, Yan V, Vogelzangs, Nicole, Yu, Lei, Bandinelli, Stefania, Benjamin, Emelia J, Bennett, David A, Boomsma, Dorret, Cannas, Alessandra, Coker, Laura H, de Geus, Eco, De Jager, Philip L, Diez-Roux, Ana V, Purcell, Shaun, Hu, Frank B, Rimm, Eric B, Hunter, David J, Jensen, Majken K, Curhan, Gary, Rice, Kenneth, Penman, Alan D, Rotter, Jerome I, Sotoodehnia, Nona, Emeny, Rebecca, Eriksson, Johan G, Evans, Denis A, Ferrucci, Luigi, Fornage, Myriam, Gudnason, Vilmundur, Hofman, Albert, Illig, Thomas, Kardia, Sharon, Kelly-Hayes, Margaret, Koenen, Karestan, Kraft, Peter, Kuningas, Maris, Massaro, Joseph M, Melzer, David, Mulas, Antonella, Mulder, Cornelis L, Murray, Anna, Oostra, Ben A, Palotie, Aarno, Penninx, Brenda, Petersmann, Astrid, Pilling, Luke C, Psaty, Bruce, Rawal, Rajesh, Reiman, Eric M, Schulz, Andrea, Shulman, Joshua M, Singleton, Andrew B, Smith, Albert V, Sutin, Angelina R, Uitterlinden, André G, Völzke, Henry, Widen, Elisabeth, Yaffe, Kristine, Zonderman, Alan B, Cucca, Francesco, Harris, Tamara, Ladwig, Karl-Heinz, Llewellyn, David J, Räikkönen, Katri, Tanaka, Toshiko, van Duijn, Cornelia M, Grabe, Hans J, Launer, Lenore J, Lunetta, Kathryn L, Mosley, Thomas H, Newman, Anne B, Tiemeier, Henning, and Murabito, Joanne

Subjects
Biological Sciences, Biomedical and Clinical Sciences, Genetics, Mental Illness, Clinical Research, Brain Disorders, Depression, Human Genome, Mental Health, 2.1 Biological and endogenous factors, Aged, Aged, 80 and over, Chromosomes, Human, Pair 5, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Center for Epidemiologic Studies Depression Scale, CHARGE consortium, depression, depressive symptoms, genetics, genome-wide association study, meta-analysis, Medical and Health Sciences, Psychology and Cognitive Sciences, Psychiatry, Biological sciences, Biomedical and clinical sciences, Psychology
Abstract

BackgroundDepression is a heritable trait that exists on a continuum of varying severity and duration. Yet, the search for genetic variants associated with depression has had few successes. We exploit the entire continuum of depression to find common variants for depressive symptoms.MethodsIn this genome-wide association study, we combined the results of 17 population-based studies assessing depressive symptoms with the Center for Epidemiological Studies Depression Scale. Replication of the independent top hits (p

Published
2013

3. Longevity candidate genes and their association with personality traits in the elderly

Author

Luciano, Michelle, Lopez, Lorna M., de Moor, Marleen H.M., Harris, Sarah E., Davies, Gail, Nutile, Teresa, Krueger, Robert F., Esko, Tõnu, Schlessinger, David, Toshiko, Tanaka, Derringer, Jaime L., Realo, Anu, Hansell, Narelle K., Pergadia, Michele L., Pesonen, Anu-Katriina, Sanna, Serena, Terracciano, Antonio, Madden, Pamela A.F., Penninx, Brenda, Spinhoven, Philip, Hartman, Catherina A., Oostra, Ben A., Janssens, Cecile A.J.W., Eriksson, Johan G., Starr, John M., Cannas, Alessandra, Ferrucci, Luigi, Metspalu, Andres, Wright, Margeret J., Heath, Andrew C., van Duijn, Cornelia M., Bierut, Laura J., Raikkonen, Katri, Martin, Nicholas G., Ciullo, Marina, Rujescu, Dan, Boomsma, Dorret I., and Deary, Ian J.

Published
2012
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5. Catches analysis of Palinurus elephas (Fabricius, 1787) in Northwestern Sardinia

Author

Tidu, Carlo, Cannas, Alessandra, Lecca, Elisabetta, Meloni, Francesca, PINNA, Maurizio, Savarino, Roberto, Tidu, Carlo, Cannas, Alessandra, Lecca, Elisabetta, Meloni, Francesca, Pinna, Maurizio, and Savarino, Roberto

Subjects
Palinurus elephas, spiny lobster, landing statistics, north western Sardinia
Abstract

In this paper we examined 20 years of catches of Palinurus elephas in northwestern Sardinia. The results showed that the fishing pressure is the most important factor controlling the landings, although natural variability can also play an important role.

Published
2003

6. Dinamica di popolazione di Ruditapes Decussatus (L) e insediamento di Rudutapes Philippinarum (Adams&Reeve) in Sardegna (Italia)

Author

Cannas, Alessandra

Subjects
BIO/07 Ecologia
Abstract

Ruditapes decussatus is a traditional resource of fishing activity in Sardinia Island. This species is not cultured, but fishermen picked them up from the bottom of brackish areas. The distribution and the population structure of Ruditapes decussatus were investigated in six coastal lagoons: Tortolì (OT) S. Giovanni Santa Gilla (CA), Marceddì, Corru S’ittiri (OR), Calich (SS) and in the Olbia gulf. In this last site were also studied the growth and the mortality. In the same area, during the study the settlement of the allochthonous species Ruditapes philippinarum was found, so the population structure of this bivalve mollusc was also studied. The samplings were seasonally, started in autumn 2008 and finished in summer 2009. Ruditapes were collected using a shellfish rake in different stations for each site (five repetitions for each of 29 sampling stations). In spring was also collected the sediment in all stations. With regard to Ruditapes decussatus, the analysis of density demonstrates a highly heterogeneous situation in the different sites. The maximum of density was measured at San Giovanni (CA), where it has reached 1,315 *m-2 specimens. In the same site, the maximum of density (considering the average between the repetition in each station) was reached equal to 507 * m-2 specimens in summer. This value is close to that observed in the Olbia Gulf and Corru s' Ittiri lagoon in spring. In other sites densities were lower, but the maximum always corresponded to spring or summer, except Marceddì (OR) where the maximum value was detected in the winter sampling. In this case, the excessive rainfall caused very low salinity and the death of almost all Ruditapes in the lagoon. Also the population structure was very heterogeneous in the sites. The length frequency distribution (oro-aboral length) was statistically different for at least two seasons for all comparisons (χ2 test, P

Published
2011

7. Survey of the genetic variability of populations of Ruditapes philippinarum from tre Gulf of Olbia (N-E Sardinia) by microsatellites = Indagine sulla variabilità genetica di popolazioni di Ruditapes philippinarum provenienti dal golfo di Olbia (N-E Sardegna)

Author

Mura, Laura, Cossu, Piero, Lai, Tiziana, Cannas, Alessandra, Floris, Rosanna, Sanna, Daria, Casu, Marco, and Fois, Nicola

Subjects
BIO/05 Zoologia
Abstract

Genetic variability was investigated at six microsatellite loci of the Manila clam Ruditapes philippinarum (Adams & Reeve, 1850) (Bivalvia) from the Gulf of Olbia (N-E Sardinia) and Sacca di Goro (N Adriatic Sea). We found no significant differentiation among Sardinian samples and between those and the Adriatic one, which suggests the absence of a founder effect in Sardinian population.

Published
2011

8. Struttura di popolazione di vongola verace (Ruditapes decussatus l.) in due lagune costiere della Sardegna = Population structure of carpet shell clam (Ruditapes decussatus l.) in two coastal lagoons of Sardinia (Italy)

Author

Cannas, Alessandra, Manca, Silvana, Trentadue, Marco, and Fois, Nicola

Subjects
BIO/05 Zoologia
Abstract

Ruditapes decussatus L. (Bivalvia) is a traditional resource for fishing activity in Sardinia Island. This species is not cultured, but fishermen pick them up from the bottom of brackish areas. The distribution and the population structure of R. decussatus were investigated in two coastal lagoons: S. Giovanni (CA) and Calich (SS). The samplings were performed seasonally from autumn 2008 to summer 2009.

Published
2011

9. Longevity candidate genes and their association with personality traits in the elderly

Author

Luciano, Michelle, Lopez, Lorna M., de Moor, Marleen H.M., Harris, Sarah E., Davies, Gail, Nutile, Teresa, Krueger, Robert F., Esko, Tõnu, Schlessinger, David, Toshiko, Tanaka, Derringer, Jaime L., Realo, Anu, Hansell, Narelle K., Pergadia, Michele L., Pesonen, Anu-Katriina, Sanna, Serena, Terracciano, Antonio, Madden, Pamela A.F., Penninx, Brenda, Spinhoven, Philip, Hartman, Catherina A., Oostra, Ben A., Janssens, A. Cecile J.W., Eriksson, Johan G., Starr, John M., Cannas, Alessandra, Ferrucci, Luigi, Metspalu, Andres, Wright, Margeret J., Heath, Andrew C., van Duijn, Cornelia M., Bierut, Laura J., Raikkonen, Katri, Martin, Nicholas G., Ciullo, Marina, Rujescu, Dan, Boomsma, Dorret I., Deary, Ian J., Luciano, Michelle, Lopez, Lorna M., de Moor, Marleen H.M., Harris, Sarah E., Davies, Gail, Nutile, Teresa, Krueger, Robert F., Esko, Tõnu, Schlessinger, David, Toshiko, Tanaka, Derringer, Jaime L., Realo, Anu, Hansell, Narelle K., Pergadia, Michele L., Pesonen, Anu-Katriina, Sanna, Serena, Terracciano, Antonio, Madden, Pamela A.F., Penninx, Brenda, Spinhoven, Philip, Hartman, Catherina A., Oostra, Ben A., Janssens, A. Cecile J.W., Eriksson, Johan G., Starr, John M., Cannas, Alessandra, Ferrucci, Luigi, Metspalu, Andres, Wright, Margeret J., Heath, Andrew C., van Duijn, Cornelia M., Bierut, Laura J., Raikkonen, Katri, Martin, Nicholas G., Ciullo, Marina, Rujescu, Dan, Boomsma, Dorret I., and Deary, Ian J.

Abstract

Human longevity and personality traits are both heritable and are consistently linked at the phenotypic level. We test the hypothesis that candidate genes influencing longevity in lower organisms are associated with variance in the five major dimensions of human personality (measured by the NEO-FFI and IPIP inventories) plus related mood states of anxiety and depression. Seventy single nucleotide polymorphisms (SNPs) in six brain expressed, longevity candidate genes (AFG3L2, FRAP1, MAT1A, MAT2A, SYNJ1 and SYNJ2) were typed in over one thousand 70-year old participants from the Lothian Birth Cohort of 1936 (LBC1936). No SNPs were associated with the personality and psychological distress traits at a Bonferroni corrected level of significance (p < 0.0002), but there was an over-representation of nominally significant (p < 0.05) SNPs in the synaptojanin-2 (SYNJ2) gene associated with agreeableness and symptoms of depression. Eight SNPs which showed nominally significant association across personality measurement instruments were tested in an extremely large replication sample of 17 106 participants. SNP rs350292, in SYNJ2, was significant: the minor allele was associated with an average decrease in NEO agreeableness scale scores of 0.25 points, and 0.67 points in the restricted analysis of elderly cohorts (most aged > 60 years). Because we selected a specific set of longevity genes based on functional genomics findings, further research on other longevity gene candidates is warranted to discover whether they are relevant candidates for personality and psychological distress traits.

Published
2011

10. Longevity candidate genes and their association with personality traits in the elderly

Author

Luciano, Michelle, primary, Lopez, Lorna M., additional, de Moor, Marleen H.M., additional, Harris, Sarah E., additional, Davies, Gail, additional, Nutile, Teresa, additional, Krueger, Robert F., additional, Esko, Tõnu, additional, Schlessinger, David, additional, Toshiko, Tanaka, additional, Derringer, Jaime L., additional, Realo, Anu, additional, Hansell, Narelle K., additional, Pergadia, Michele L., additional, Pesonen, Anu‐Katriina, additional, Sanna, Serena, additional, Terracciano, Antonio, additional, Madden, Pamela A.F., additional, Penninx, Brenda, additional, Spinhoven, Philip, additional, Hartman, Catherina A., additional, Oostra, Ben A., additional, Janssens, A. Cecile J.W., additional, Eriksson, Johan G., additional, Starr, John M., additional, Cannas, Alessandra, additional, Ferrucci, Luigi, additional, Metspalu, Andres, additional, Wright, Margeret J., additional, Heath, Andrew C., additional, van Duijn, Cornelia M., additional, Bierut, Laura J., additional, Raikkonen, Katri, additional, Martin, Nicholas G., additional, Ciullo, Marina, additional, Rujescu, Dan, additional, Boomsma, Dorret I., additional, and Deary, Ian J., additional

Published
2011
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15. Family burden in bipolar disorders: results from the Italian Mood Disorders Study (IMDS).

Author

Magliano L, Orrico A, Fiorillo A, Del Vecchio H, Castiello G, Malangone C, De Rosa C, Capuano V, Maj M, Torchio E, Franzoi V, Pingani L, Curti C, Spanarello S, Scattina M, Fuchs H, Test GR, Ferrigno J, Minciotti E, Innocente P, Bardicchia F, Galli A, La Rovere R, Maroncelli M, Iapichino S, Pannozzo M, Nuccetelli F, Di Nunzio R, Armellino R, Palladino C, Delcuratolo V, Cadoni M, Cannas A, Caniglia A, and Cudia M

Subjects
Female, Humans, Italy, Male, Middle Aged, Bipolar Disorder therapy, Cost of Illness, Family Health
Abstract

Aims: To explore: a) the burden of care, and the professional and social support in relatives of patients with bipolar disorders; b) the psychosocial interventions provided to patients and their families by Italian mental health centres., Methods: 342 outpatients with a bipolar disorder and their key-relatives were randomly recruited in 26 Italian mental health centres, randomly selected and stratified by geographical area and population density. Family burden was explored in relation to: a) patient's clinical status and disability; b) relatives' social and professional support; c) interventions received by patients and their families; d) geographical area., Results: In the previous two months, global functioning was moderately impaired in 36% of the patients, and severely impaired in 34% of them. Twenty-one percent of patients attended a rehabilitative programme, and 3% of their families received a psychoeducational intervention. Burden was higher when patient's symptoms and disability were more severe, the relatives had poorer psychological support and help in emergencies by the social network, and the family lived in Southern Italy. Differences in family burden in relation to geographical area disappeared when psychosocial interventions were provided., Conclusion: This study highlights the need to increase the availability of rehabilitative interventions for patients with bipolar disorders and of psychological support for their families, especially in Southern Italy.

Published
2009

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