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2. Nasal cytology as a reliable non-invasive procedure to phenotype patients with type 2 chronic rhinosinusitis with nasal polyps

Author

Paoletti, Giovanni, Malvezzi, Luca, Riccio, Anna Maria, Descalzi, Desideria, Pirola, Francesca, Russo, Elena, De Ferrari, Laura, Racca, Francesca, Ferri, Sebastian, Messina, Maria Rita, Puggioni, Francesca, Nappi, Emanuele, Bagnasco, Diego, Canevari, Frank Rikki, Grizzi, Fabio, Mercante, Giuseppe, Spriano, Giuseppe, Canonica, Giorgio Walter, and Heffler, Enrico

Published
2022
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8. Management of patients with chronic rhinosinusitis with nasal polyps (CRSwNP): Results from a survey among allergists and clinical immunologists of the North-west and Center Italy Inter-Regional Sections of SIAAIC and otorhinolaryngologists of National IAR

Author

Bagnasco, Diego, primary, Brussino, Luisa, additional, Biagini, Cesare, additional, Cosmi, Lorenzo, additional, De Corso, Eugenio, additional, La Mantia, Ignazio, additional, Macchi, Alberto, additional, Maggiore, Giandomenico, additional, Matucci, Andrea, additional, Nicola, Stefania, additional, Passalacqua, Giovanni, additional, Presutti, Livio, additional, Seccia, Veronica, additional, Vultaggio, Alessandra, additional, Riparbelli, Michele, additional, Sartor, Chiara, additional, Parronchi, Paola, additional, and Canevari, Frank Rikki Mauritz, additional

Published
2024
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10. Multiple spontaneous skull base cerebrospinal fluid leaks: some insights from an international retrospective collaborative study

Author

Dallan, Iacopo, Cambi, Christina, Emanuelli, Enzo, Cazzador, Diego, Canevari, Frank Rikki, Borsetto, Daniele, Tysome, James R., Donnelly, Neil P., Rigante, Mario, Georgalas, Christos, Alobid, Isam, Molteni, Gabriele, Marchioni, Daniele, Shahzada, Ahmed Khuram, Scarano, Mariella, Seccia, Veronica, and Pasquini, Ernesto

Published
2020
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14. Raccomandazioni pratiche nella gestione ambulatoriale della rinosinusite cronica con poliposi nasale severa, nell’era dei biologici

Author

De Corso, Eugenio, primary, Pipolo, Carlotta, additional, Cantone, Elena, additional, Ottaviano, Giancarlo, additional, Gallo, Stefania, additional, Trimarchi, Matteo, additional, Torretta, Sara, additional, Cavaliere, Carlo, additional, Lucidi, Daniela, additional, Seccia, Veronica, additional, Settimi, Stefano, additional, Canevari, Frank Rikki Mauritz, additional, Pasquini, Ernesto, additional, La Mantia, Ignazio, additional, Garzaro, Massimiliano, additional, Bellocchi, Gianluca, additional, De Benedetto, Michele, additional, Lombardo, Nicola, additional, Macchi, Alberto, additional, Malvezzi, Luca, additional, Motta, Gaetano, additional, Vicini, Claudio, additional, Maselli, Alessandro, additional, Dell’Era, Valeria, additional, Dragonetti, Alberto, additional, Asprea, Francesco, additional, Lupato, Valentina, additional, Ghidini, Angelo, additional, Masieri, Simonetta, additional, Mattavelli, Davide, additional, Salzano, Francesco Antonio, additional, Passali, Desiderio, additional, Galli, Jacopo, additional, and Pagella, Fabio, additional

Published
2023
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15. Diagnostic therapeutic assistance pathway (PDTA) of type 2 chronic rhinosinusitis

Author

Canevari, Frank Rikki, primary, Giorli, Alessia, additional, Monti, Giulia, additional, Biagini, Cesare, additional, Bagnasco, Diego, additional, Cavaliere, Carlo, additional, Pipolo, Carlotta, additional, De Corso, Eugenio, additional, Gelardi, Matteo, additional, Gramellini, Giulia, additional, Ioppi, Alessandro, additional, La Mantia, Ignazio, additional, Malvezzi, Luca, additional, Bignami, Maurizio, additional, Dehgani-Mobaraki, Puya, additional, Seccia, Veronica, additional, Maggiore, Giandomenico, additional, and Macchi, Alberto, additional

Published
2023
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18. Electric Bioimpedance Sensing for the Detection of Head and Neck Squamous Cell Carcinoma

Author

Carobbio, Andrea Luigi Camillo, primary, Cheng, Zhuoqi, additional, Gianiorio, Tomaso, additional, Missale, Francesco, additional, Africano, Stefano, additional, Ascoli, Alessandro, additional, Fragale, Marco, additional, Filauro, Marta, additional, Marchi, Filippo, additional, Guastini, Luca, additional, Mora, Francesco, additional, Parrinello, Giampiero, additional, Canevari, Frank Rikki Mauritz, additional, Peretti, Giorgio, additional, and Mattos, Leonardo S., additional

Published
2023
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20. Practical recommendations for managing severe chronic rhinosinusitis with nasal polyps in the era of biologics

Author

De Corso, Eugenio, Pipolo, Carlotta, Cantone, Elena, Ottaviano, Giancarlo, Gallo, Stefania, Trimarchi, Matteo, Torretta, Sara, Cavaliere, Carlo, Lucidi, Daniela, Seccia, Veronica, Settimi, Stefano, Canevari, Frank Rikki Mauritz, Pasquini, Ernesto, La Mantia, Ignazio, Garzaro, Massimiliano, Bellocchi, Gianluca, De Benedetto, Michele, Lombardo, Nicola, Macchi, Alberto, Malvezzi, Luca, Motta, Gaetano, Vicini, Claudio, Maselli, Alessandro, Dell'Era, Valeria, Dragonetti, Alberto, Asprea, Francesco, Lupato, Valentina, Ghidini, Angelo, Masieri, Simonetta, Mattavelli, Davide, Salzano, Francesco Antonio, Passali, Desiderio, Galli, Jacopo, Pagella, Fabio, De Corso, Eugenio, Pipolo, Carlotta, Cantone, Elena, Ottaviano, Giancarlo, Gallo, Stefania, Trimarchi, Matteo, Torretta, Sara, Cavaliere, Carlo, Lucidi, Daniela, Seccia, Veronica, Settimi, Stefano, Canevari, Frank Rikki Mauritz, Pasquini, Ernesto, La Mantia, Ignazio, Garzaro, Massimiliano, Bellocchi, Gianluca, De Benedetto, Michele, Lombardo, Nicola, Macchi, Alberto, Malvezzi, Luca, Motta, Gaetano, Vicini, Claudio, Maselli, Alessandro, Dell'Era, Valeria, Dragonetti, Alberto, Asprea, Francesco, Lupato, Valentina, Ghidini, Angelo, Masieri, Simonetta, Mattavelli, Davide, Salzano, Francesco Antonio, Passali, Desiderio, Galli, Jacopo, and Pagella, Fabio

Subjects
chronic rhinosinusiti, Type 2 inflammation, practical recommendation, biologic, nasal polyp
Abstract

Objective: We conducted a national survey to understand how rhinology practice has changed with the advent of biologics and how this affected patients with uncontrolled, severe chronic rhinosinusitis with nasal polyps (CRSwNP). We aimed to analyse the results of the survey and infer practical recommendations for clinical practice. Methods: A group of ear, nose, and throat specialists (ENTs) experienced in the management of CRSwNP developed a 74-question survey. ENTs from rhinology centres authorised to prescribe biologics in the context of the national health system were invited to answer it between 01/05/2022 and 31/07/2022. The responses underwent descriptive analyses, and the authors discussed the results and derived practical recommendations for clinical practice. Results: ENTs working in rhinology centres changed their practices coinciding with the advent of biologics. CRSwNP evaluations have become more complex because they involve diagnostic confirmation, determining the patients' immunologic profile, and other factors. We observed heterogenous behaviours in practice that may be conditioned by the novelty of the topic. The results of the survey were used to develop practical recommendations for ENTs and are summarised herein. Conclusions: Clinical practice in rhinology outpatient clinics has changed profoundly in the era of biologics. Our practical recommendations for clinicians working in rhinology centres are expected to help standardise practice and improve care.

Published
2023

21. Management of patients with chronic rhinosinusitis and nasal polyposis in Italy: expert opinion on the diagnostic-therapeutic approach

Author

Menzella, Francesco, Bagnasco, Diego, Bilò, Maria Beatrice, Caminati, Marco, Cavaliere, Carlo, Contoli, Marco, De Massimi, Alessio, Gallo, Stefania, Matucci, Andrea, Ottaviano, Giancarlo, Rossi, Oliviero, Seccia, Veronica, Emmi, Martino, Canevari, Frank Rikki, Menzella, Francesco, Bagnasco, Diego, Bilò, Maria Beatrice, Caminati, Marco, Cavaliere, Carlo, Contoli, Marco, De Massimi, Alessio, Gallo, Stefania, Matucci, Andrea, Ottaviano, Giancarlo, Rossi, Oliviero, Seccia, Veronica, Emmi, Martino, and Canevari, Frank Rikki

Abstract

Chronic rhinosinusitis (CRS) is an inflammatory disease that affects the nasal mucosa and the paranasal sinuses; it can be characterized by nasal polyposis (CRSwNP) in up to 30% of cases. CRSwNP is frequently associated with bronchial asthma and patients affected show a greater severity of clinical disease with a significantly worse quality of life. CRSwNP shows predominantly an underlying activation of type 2 inflammatory pathways with the increase of eosinophils, IgE, interleukin (IL)-4, IL-5 and IL-13. Biological drugs that target inflammatory molecules are currently a therapeutic option recognized by guidelines for the treatment of uncontrolled form of the disease. The correct definition of the target patient, the type of biological drug to be used and the timing of intervention are crucial to guarantee a personalized therapy and optimize the cost/effectiveness of the treatment. A panel of Italian pneumologists, allergologists, immunologists and ear, nose and throat specialists discussed in a series of virtual expert meetings the main criteria for patient characterization and therapeutic decision, highlighting multidisciplinarity, the constant dialogue between doctor and patient, the organization in networks and the use of registries as strategies to implement the management of CRSwNP patients, to reach the personalization of the treatment and the best use of the biological drug(s).

Published
2023

22. Sense of smell in chronic rhinosinusitis: A multicentric study on 811 patients

Author

Macchi, Alberto, primary, Giorli, Alessia, additional, Cantone, Elena, additional, Carlotta Pipolo, Giorgia, additional, Arnone, Flavio, additional, Barbone, Umberto, additional, Bertazzoni, Giacomo, additional, Bianchini, Chiara, additional, Ciofalo, Andrea, additional, Cipolla, Federica, additional, De Massimi, Alessio, additional, De Vita, Carla, additional, Di Lieto, Cristina, additional, Ghidini, Angelo, additional, Govoni, Marco, additional, Gramellini, Giulia, additional, Maselli Del Giudice, Alessandro, additional, Ottaviano, Giancarlo, additional, Seccia, Veronica, additional, Sireci, Federico, additional, Sollini, Giacomo, additional, Staffieri, Claudia, additional, Gallo, Stefania, additional, Heffler, Enrico, additional, Mantia, Ignazio La, additional, De Corso, Eugenio, additional, Canevari, Frank Rikki, additional, Lombardo, Nicola, additional, Malvezzi, Luca, additional, Orietti, Gabriele, additional, Pasquini, Ernesto, additional, Presutti, Livio, additional, and Monti, Giulia, additional

Published
2023
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23. La gestione del paziente con rinosinusite cronica e poliposi nasale in Italia: expert opinion sul percorso diagnostico-terapeutico

Author

Menzella, Francesco, primary, Bagnasco, Diego, additional, Bilò, Maria Beatrice, additional, Caminati, Marco, additional, Cavaliere, Carlo, additional, Contoli, Marco, additional, De Massimi, Alessio, additional, Gallo, Stefania, additional, Matucci, Andrea, additional, Ottaviano, Giancarlo, additional, Rossi, Oliviero, additional, Seccia, Veronica, additional, Emmi, Martino, additional, and Canevari, Frank Rikki, additional

Published
2023
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24. Correction to: Multiple spontaneous skull base cerebrospinal fluid leaks: some insights from an international retrospective collaborative study

Author

Dallan, Iacopo, Cambi, Christina, Emanuelli, Enzo, Cazzador, Diego, Canevari, Frank Rikki, Borsetto, Daniele, Tysome, James R., Donnelly, Neil P., Rigante, Mario, Georgalas, Christos, Alobid, Isam, Molteni, Gabriele, Marchioni, Daniele, Shahzada, Ahmed Khuram, Scarano, Mariella, Seccia, Veronica, and Pasquini, Ernesto

Published
2020
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25. Sense of smell in chronic rhinosinusitis: a multicentric study on 811 patients

Author

Macchi, Alberto, Giorli, Alessia, Cantone, Elena, Carlotta Pipolo, Giorgia, Arnone, Flavio, Barbone, Umberto, Bertazzoni, Giacomo, Bianchini, Chiara, Ciofalo, Andrea, Cipolla, Federica, De Massimi, Alessio, De Vita, Carla, Di Lieto, Cristina, Ghidini, Angelo, Govoni, Marco, Gramellini, Giulia, Maselli Del Giudice, Alessandro, Ottaviano, Giancarlo, Seccia, Veronica, Sireci, Federico, Sollini, Giacomo, Staffieri, Claudia, Gallo, Stefania, Heffler, Enrico, Mantia, Ignazio La, De Corso, Eugenio, Canevari, Frank Rikki, Lombardo, Nicola, Malvezzi, Luca, Orietti, Gabriele, Pasquini, Ernesto, Presutti, Livio, Monti, Giulia, Macchi1, Alberto, Giorli, Alessia, Cantone, Elena, Carlotta Pipolo, Giorgia, Arnone, Flavio, Barbone, Umberto, Bertazzoni, Giacomo, Bianchini, Chiara, Ciofalo, Andrea, Cipolla, Federica, De Massimi, Alessio, De Vita, Carla, Di Lieto, Cristina, Ghidini, Angelo, Govoni, Marco, Gramellini, Giulia, Maselli Del Giudice, Alessandro, Ottaviano, Giancarlo, Seccia, Veronica, Sireci, Federico, Sollini, Giacomo, Staffieri, Claudia, Gallo, Stefania, Heffler, Enrico, La Mantia, Ignazio, De Corso, Eugenio, Rikki Canevari, Frank, Lombardo, Nicola, Malvezzi, Luca, Orietti, Gabriele, Pasquini, Ernesto, Presutti, Livio, and Monti, Giulia

Subjects
Microbiology (medical), CRSwNP, QoL (quality of life), olfactory dysfunction, smell, type 2, Immunology, Immunology and Allergy, General Earth and Planetary Sciences
Abstract

IntroductionThe impairment of the sense of smell is often related to chronic rhinosinusitis (CRS) with or without nasal polyps (CRSwNP, CRSsNP). CRSwNP is a frequent condition that drastically worsens the quality of life of those affected; it has a higher prevalence than CRSsNP. CRSwNP patients experience severe loss of smell with earlier presentation and are more likely to experience recurrence of their symptoms, often requiring revision surgery.MethodsThe present study performed a multicentric data collection, enrolling 811 patients with CRS divided according to the inflammatory endotype (Type 2 and non-Type 2). All patients were referred for nasal endoscopy for the assessment of nasal polyposis using nasal polyp score (NPS); Sniffin’ Sticks olfactory test were performed to measure olfactory function, and SNOT-22 (22-item sinonasal outcome test) questionnaire was used to assess patients’ quality of life; allergic status was evaluated with skin prick test and nasal cytology completed the evaluation when available.ResultsData showed that Type 2 inflammation is more common than non-type 2 (656 patients versus 155) and patients suffer from worse quality of life and nasal polyp score. Moreover, 86.1% of patients with Type 2 CRSwNP were affected by a dysfunction of the sense of smell while it involved a lesser percentage of non-Type 2 patients. Indeed, these data give us new information about type-2 inflammation patients’ characteristics.DiscussionThe present study confirms that olfactory function weights on patients’ QoL and it represents an important therapeutic goal that can also improve patients’ compliance when achieved. In a future – and present – perspective of rhinological precision medicine, an impairment of the sense of smell could help the clinician to characterize patients better and to choose the best treatment available.

Published
2023

26. Dupilumab in the treatment of severe uncontrolled chronic rhinosinusitis with nasal polyps): a multicentric observational phase IV real‐life study (DUPIREAL)

Author

De Corso Eugenio, Pasquini, Ernesto, Trimarchi, Matteo, La Mantia Ignazio, Pagella, Fabio, Ottaviano, Giancarlo, Garzaro, Massimiliano, Pipolo, Carlotta, Torretta, Sara, Seccia, Veronica, Cantone, Elena, Ciofalo, Andrea, Lucidi, Daniela, Fadda Gian Luca, Pafundi Pia Clara, Settimi, Stefano, Montuori, Claudio, Anastasi, Francesca, Pagliuca, Giulio, Ghidini, Angelo, Cavaliere, Carlo, Maffei, Marianna, Bussu, Francesco, Gallo, Stefania, Canevari Frank Rikki Mauritz, Paludetti, Gaetano, Galli, Jacopo, Spanu, Camilla, Porru Davide Paolo, Lo Verde Simone, Corbò, Marco, Cantiani, Alessandro, Furno, Daniela, D’Agostino, Giuseppe, D’Auria Leandro Maria, De Maio Gabriele, Di Bella Giuseppe Alberto, Penazzi, Daniele, Mele Dario Antonio, Di Cesare Tiziana, Andrea, Rampi, Umberto, Tanzini, Saccardo, Tommaso, Roccuzzo, Giuseppe, Cipolla, Federica, Ragusa, Martina, Grigaliute, Egle, Alicandri Ciufelli Matteo, Roncadi, Leonardo, Rizzo, Davide, De Vita Carla, Farneti, Paolo, Todero, Gabriella, Cristofani‐mencacci, Lodovica, Statuti, Erica, Cavallo, Giovanni, Urbanelli, Anastasia, Ferrella, Francesco, Arnone, Flavio, Di Nola Claudio, Pignataro, Lorenzo, Nava, Nicolò, Russo, Paolo, Savastano, Vincenzo, Masieri, Simonetta, Dell’Era, Valeria, Aluffi Valletti Paolo, Sovardi, Fabio, Siragusa, Vera, Clemenzi, Veronica, Stolfa, Andrea, Simoni, Edi, and Astolfi, Laura

Subjects
dupilumab, smell, biologics, dupireal, crswnp, asthma, biologics, chronic rhinosinusitis with nasal polyps, dupilumab, smell, asthma, chronic rhinosinusitis with nasal polyps
Published
2023

27. Survey on Use of Local and Systemic Corticosteroids in the Management of Chronic Rhinosinusitis with Nasal Polyps: Identification of Unmet Clinical Needs

Author

De Corso, Eugenio, primary, Pipolo, Carlotta, additional, Cantone, Elena, additional, Ottaviano, Giancarlo, additional, Gallo, Stefania, additional, Canevari, Frank Rikki Mauritz, additional, Macchi, Alberto, additional, Monti, Giulia, additional, Cavaliere, Carlo, additional, La Mantia, Ignazio, additional, Torretta, Sara, additional, Bussu, Francesco, additional, Scarano, Emanuele, additional, Petrone, Paolo, additional, Ghidini, Angelo, additional, Lucidi, Daniela, additional, Garzaro, Massimiliano, additional, Trimarchi, Matteo, additional, Seccia, Veronica, additional, Passali, Giulio Cesare, additional, Salsi, Daria, additional, Cuda, Domenico, additional, Pasquini, Ernesto, additional, Malvezzi, Luca, additional, Settimi, Stefano, additional, Paludetti, Gaetano, additional, and Galli, Jacopo, additional

Published
2022
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31. Endoscopic Endonasal Prelacrimal Approach: Radiological Considerations, Morbidity, and Outcomes

Author

Arosio, Alberto Daniele, primary, Valentini, Marco, additional, Canevari, Frank Rikki, additional, Volpi, Luca, additional, Karligkiotis, Apostolos, additional, Terzakis, Dimitris, additional, Battaglia, Paolo, additional, Georgalas, Christos, additional, Bignami, Maurizio, additional, Castelnuovo, Paolo, additional, and Turri‐Zanoni, Mario, additional

Published
2020
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34. SmartProbe: a bioimpedance sensing system for head and neck cancer tissue detection

Author

Cheng, Zhuoqi, primary, Carobbio, Andrea Luigi Camillo, additional, Soggiu, Lara, additional, Migliorini, Marco, additional, Guastini, Luca, additional, Mora, Francesco, additional, Fragale, Marco, additional, Ascoli, Alessandro, additional, Africano, Stefano, additional, Caldwell, Darwin G., additional, Canevari, Frank Rikki Mauritz, additional, Parrinello, Giampiero, additional, Peretti, Giorgio, additional, and Mattos, Leonardo S., additional

Published
2020
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36. RT-QuIC detection of alpha-synuclein seeds in olfactory mucosa brushings of patients with Dementia with Lewy bodies

Author

Novi, (Novi, G, ( 1 ), G., Perra, Francesco, (Perra, D, ( 2 ), D., Carobbio, ANDREA LUIGI CAMILLO, Alc, (Carobbio, ( 3 ), A. L. C., Schenone, Guido, (Schenone, G, ( 4 ), G., Canevari, FRANK RIKKI MAURITZ, Frm, (Canevari, ( 3 ), F. R. M., Pardini, (Pardini, M, ( 1 ), M., Arnaldi, (Arnaldi, D, ( 1 ), D., Morbelli, SILVIA DANIELA, (Morbelli, Sd, ( 5 ), S. D., Cocchiara, Francesco, (Cocchiara, P, ( 2 ), P., Brozzetti, (Brozzetti, L, ( 2 ), L., Capaldi, (Capaldi, S, ( 2 ), S., Bongianni, (Bongianni, M, ( 2 ), M., Zanusso, (Zanusso, G, ( 2 ), G., Nobili, (Nobili, F, and F. ).

Published
2020

37. Ipsilateral Nasoseptal Flap Pedicle for Transpterygoid Approach: Technical Note.

Author

Anania, Pasquale, Ceraudo, Marco, Prior, Alessandro, Fiaschi, Pietro, Zona, Gianluigi, Canevari, Frank Rikki, and Rossi, Diego Criminelli

Subjects
SKULL base, CEREBROSPINAL fluid leak, SPHENOID sinus, OPERATIVE surgery, LITERATURE reviews
Abstract

Introduction: Transpterygoid approach is an expanded endonasal approach (EEA) that allows surgical access to the medial infratemporal fossa, to the skull base area of petrous bone and to the Meckel's cave. During this approach, a sacrifice of sphenopalatine artery is often required, leading to the need of contralateral Hadad-Bassagasteguy flap (HBF) or alternative reconstructive techniques. Materials and Methods: We report a case of spontaneous CSF leak due to a meningo-encephalocele in the left lateral recess of sphenoid sinus, in which an ispilateral nasoseptal flap was harvest and sphenopalatine artery was preserved. Results: We described the surgical technique adopted to preserve the ipsilateral nasoseptal vascular pedicle during transpterygoid approach and we performed a review of the pertinent literature. Conclusion: Wide exposure of the pterygoid base through transpterygoid approach could be obtained preserving the sphenopalatine artery, allowing skull base reconstruction with ipsilateral nasoseptal flap. [ABSTRACT FROM AUTHOR]

Published
2021
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38. Canine Fossa Puncture for the Management of Maxillary Sinusitis

Author

Sireci, Federico, Martines, Francesco, De Bernardi, Francesca, Poma, Salvatore, Dispensa, Francesco, Galletti, Bruno, Galletti, Francesco, and Canevari, Frank Rikki

Subjects
Maxillary sinusitis, Canine fossa puncture (cfp), Canine fossa puncture (cfp), Maxillary sinusitis, Middle meatal antrostomy (mma), Middle meatal antrostomy (mma)
Published
2019

42. Endoscopic Endonasal Prelacrimal Approach: Radiological Considerations, Morbidity, and Outcomes.

Author

Arosio, Alberto Daniele, Valentini, Marco, Canevari, Frank Rikki, Volpi, Luca, Karligkiotis, Apostolos, Terzakis, Dimitris, Battaglia, Paolo, Georgalas, Christos, Bignami, Maurizio, Castelnuovo, Paolo, and Turri‐Zanoni, Mario

Abstract

Objective/Hypothesis: This study describes a multicentric experience with the use of prelacrimal approach (PLA), focusing on preoperative radiological parameters potentially associated with surgical outcomes and postoperative morbidity. Study Design: Retrospective case‐series. Methods: A retrospective review of patients undergoing PLA in three European referral centers was performed. The post‐operative morbidity was analyzed in relation to two radiological parameters: width of prelacrimal recess (WPR) and internal angle of pyriform notch (APN). Results: The study included 28 patients affected by Schneiderian papilloma (20 cases), inflammatory disease (6 cases), schwannoma (1 case), and osteoma (1 case). The most reported sequela was paresthesia of ipsilateral anterior superior alveolar process (25% of the cases). An association between post‐operative morbidity and APN was observed (P =.047). Conclusions: Preoperative radiological evaluation of WPR is crucial in understanding the feasibility of the approach, while APN measurement may predict postoperative morbidity, which is paramount in the patients' counseling. Level of Evidence: 4 case‐series Laryngoscope, 131:1715–1721, 2021 [ABSTRACT FROM AUTHOR]

Published
2021
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43. Cochlear Implantation as a Treatment for Sudden Autoimmune Sensorineural Hearing Loss in a Patient Affected by Eosinophilic Granulomatosis with Polyangiitis: A Case Report and A Review of Literature.

Author

Cacco, Tommaso, Castello, Eolo, Canevari, Frank Rikki Mauritz, Laborai, Andrea, Grillone, Alessandra, Zanetti, Diego, and Peretti, Giorgio

Subjects
AUTOIMMUNE disease diagnosis, DIAGNOSIS of deafness, AUDIOLOGY, AUDIOMETRY, SPEECH audiometry, AUTOIMMUNE diseases, COCHLEAR implants, DEAFNESS, HEARING levels, INNER ear, SPEECH perception, CHURG-Strauss syndrome, DISEASE management, TREATMENT effectiveness, SUDDEN onset of disease, SYMPTOMS
Abstract

Objective: To report presentation, diagnostic process, management and outcome of a case of autoimmune inner ear disease (AIED) related with Churg-Strauss syndrome, also known as eosinophilic granulomatosis with polyangiitis (EGPA), treated with cochlear implantation, and review of relevant literature. Case presentation and management: A retrospective case report of AIED associated with EGPA treated with cochlear implantation was described. A multi-step approach for diagnosis and confirmation of AIED and hearing rehabilitation was conducted, eventually leading to left cochlear implantation. Results: The surgery was without complications and postoperative course was uneventful. Two years after surgery, pure-tone and speech soundfield audiometry with left cochlear implant switched on showed a good improvement in pure-tone threshold and a word recognition score of 50% at 60 dB nHL. Literature review does not report any previous case of AIED EGPA-related. Conclusions: Cochlear implantation in AIED EGPA-related have been shown to be a viable treatment option in a stabilized phase of disease. [ABSTRACT FROM AUTHOR]

Published
2021
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44. Septal branches of the anterior ethmoidal artery: anatomical considerations and clinical implications in the management of refractory epistaxis.

Author

Arosio, Alberto Daniele, Turri-Zanoni, Mario, Battaglia, Paolo, Castelnuovo, Paolo, Stamm, Aldo Cassol, Salzano, Giovanni, Romano, Antonio, and Canevari, Frank Rikki

Subjects
NOSEBLEED, PARANASAL sinuses, NASAL cavity, ENDOSCOPIC surgery, DISEASE relapse, SURGICAL complications, ANATOMY
Abstract

Purpose: Epistaxis is a commonly presenting complaint. In severe cases, nosebleeds may occur despite antero-posterior nasal packing and often in the absence of identifiable sources of bleeding. In such cases, epistaxis may occur from septal branches of the anterior ethmoidal artery (sbAEA). The purposes of this study are to highlight the clinical role of the sbAEA in different fields of endoscopic endonasal surgery and to evaluate the efficacy and safety of their selective endoscopic endonasal ligation in the management of refractory epistaxis.Methods: A retrospective review was performed of all patients presenting with epistaxis who underwent endoscopic endonasal coagulation of sbAEA in three Italian tertiary-care referral centers between October 2010 and October 2017.Results: A total of 30 patients met the inclusion criteria. Sixteen patients had never experienced nosebleeds before, while 14 patients recalled previous epistaxes. Seventeen patients were treated under local anesthetic, while 13 required general anesthesia. No intra- or post-operative complications were observed and none of the patients received nasal packing after the procedure. In all cases the coagulation was effective in controlling the bleeding, with only two relapses in the series (2/30, 6.7%).Conclusions: The sbAEA are of great interest in endoscopic endonasal surgery, both as surgical landmarks and as feeding vessels for a variety of pedicled nasal flaps. What is more, they can be crucial for the management of refractory epistaxis. Their selective endoscopic coagulation represents an effective and safe procedure in cases of difficult-to-control epistaxis from the upper nasal fossa, with several advantages over nasal packing. [ABSTRACT FROM AUTHOR]

Published
2018
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50. The endoscopic transnasal paraseptal approach to a sphenoid sinus osteoma: case report and literature review

Author

Canevari, Frank Rikki, Giourgos, Georgios, and Pistocchini, Andrea

Subjects
Diagnosis, Care and treatment, Case studies, Osteoma -- Diagnosis -- Care and treatment -- Case studies
Abstract

Osteomas are the most common benign tumors of the nose and paranasal sinuses. Their symptoms, which are nonspecific, occur as the result of a blocked nasal airflow or, in some [...]

Published
2013

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