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This book is an illuminating publication that explores the cutting-edge research and potential of natural compounds in the fight against cancer. This book provides a comprehensive and accessible overview of the diverse range of nature-based compounds derived from plants, marine organisms, fungi, and other sources, which have shown promising anti-cancer properties. Cancer remains one of the most challenging health issues worldwide, and the search for innovative and effective treatments continues. This book delves into the historical use of natural compounds in traditional medicine, highlighting their evolution into modern cancer research. With a focus on molecular mechanisms, the book reveals how these natural compounds combat cancer cells, induce apoptosis, and inhibit tumor angiogenesis, among other critical processes. Bringing together the latest research and advancements, this publication showcases preclinical studies demonstrating the efficacy of natural compounds in cell and animal models. Furthermore, it presents insights from clinical trials investigating the safety and potential benefits of natural compounds in cancer patients, thus bridging the gap between lab findings and real-world applications. Readers of all backgrounds, from researchers to healthcare professionals, will appreciate the valuable content presented in this book. The book discusses the advantages of natural compounds over traditional cancer treatments and addresses challenges in their development, including standardization and regulatory aspects. One of the book's key strengths lies in its exploration of integrative approaches, where natural compounds are combined with existing cancer therapies, offering a potential avenue for enhanced treatment outcomes and reduced side effects. With its wide-ranging scope, this book aims to serve as an essential resource for the academic community, healthcare practitioners, and students in oncology-related disciplines. Whether you seek a deeper understanding of molecular intricacies or new approaches to incorporate into clinical practice, this publication offers valuable insights and inspiration. As we forge ahead in the battle against cancer, this book stands as a beacon of hope, highlighting the immense potential of nature's offerings in our pursuit of effective cancer treatments as well as preventive strategies against cancer.

The use of different foods, herbs, and spices to treat or prevent disease has been recorded for thousands of years. Egyptian papyrus, hieroglyphics and ancient texts from the Middle East have described the cultivation and preparations of herbs and botanicals to “cure the sick.” There are even older records from China and India. Some ancient scripts describe the use of medicinal plants which have never been seen within European cultures. Indeed, all ancient civilizations have pictorial records of different foods, herbs, and spices being used for medical purposes. However, there are fundamental questions pertaining to the scientific evidence for the use of these agents or their extracts in modern medicine. There have been considerable advances in scientific techniques over the last few decades. These have been used to examine the composition and applications of traditional cures. Modern science has also seen the investigation of herbs, spices and botanicals beyond their traditional usage. For example, plants which have been used for “digestion” or “medical ills” since time immemorial are now being investigated for anti-cancer properties or their toxicity, using high throughput screening. Techniques also include molecular biology, cellular biochemistry, physiology, endocrinology and even medical imaging. However, much of the material relating to the scientific basis or applications of traditional foods, herbs, spices and botanicals is scattered among various sources. The widespread applicability of foods or botanicals is rarely described and cautionary notes on toxicity are often ignored. These questions are explored in Ancient and Traditional Foods, Plants, Herbs and Spices used in Cancer.Features Provides an evidenced-based approach in describing usage and applications of traditional foods and botanicals in prevention and treatment of cancer Contains chapters on biomedical research related to cancer studies Discusses extraction and analysis of active agents, in vitro studies, pre-clinical investigations in animals, and clinical studies Bridges modern day sciences with historical backgrounds related to foods and plants With contributions from leading international experts including those from world renowned institutions, this book is a reference for oncologists, physicians, health scientists, healthcare workers, pharmacologists, and research scientists.

Winner, 2024 Choice Outstanding Academic TitleIn American politics, medical innovation is often considered the domain of the private sector. Yet some of the most significant scientific and health breakthroughs of the past century have emerged from government research institutes. The U.S. National Cancer Institute (NCI) is tasked with both understanding and eradicating cancer—and its researchers have developed a surprising expertise in virus research and vaccine development.An Ungovernable Foe examines seventy years of federally funded scientific breakthroughs in the laboratories of the NCI to shed new light on how bureaucratic organizations nurture innovation. Natalie B. Aviles analyzes research and policy efforts around the search for a viral cause of leukemia in the 1960s, the discovery of HIV and the development of AIDS drugs in the 1980s, and the invention of the HPV vaccine in the 1990s. She argues that the NCI transformed generations of researchers into innovative public servants who have learned to balance their scientific and bureaucratic missions. These “scientist-bureaucrats” are simultaneously committed to conducting cutting-edge research and stewarding the nation's investment in cancer research, and as a result they have developed an unparalleled expertise. Aviles demonstrates how the interplay of science, politics, and administration shaped the NCI into a mission-oriented agency that enabled significant breakthroughs in cancer research—and in the process, she shows how organizational cultures indelibly stamp scientific work.

The comprehensive information about the inverse relationship between the incidence of cancer and the consumption of natural food has impacted our understanding of the biochemical mechanisms behind cancer and its treatment. Functional Foods for Health Maintenance: Understanding their Role in Cancer Prevention is a review of pre-clinical studies unraveling the chemotherapeutic potential of phytochemicals and other food sources. The editors attempt to summarize the evidence, methods and techniques for identifying specific nutraceuticals and foods capable of interfering and reducing the risk of cancer. The book compiles 19 edited chapters that cover the chemopreventive effects of different phytochemicals, animal and stem cell models for cancer prevention, and novel nanotechnology-based nutraceuticals. The contributors have also highlighted the techniques employed for the detection of cancer with a review on cancer biomarkers. The book is a resource for post-graduate students and researchers working in the field of nutrition, molecular biology, chemoprevention, biochemistry and pharmaceutical sciences.

For more than fifty years, we have been waging, but not winning, the war on cancer. We're better than ever at treating the disease, yet cancer still claims the lives of one in five men and one in six women in the US. The astonishing news is that up to two-thirds of all cancer cases are linked to preventable environmental causes. If we can stop cancer before it begins, why don't we? That was the question that motivated Kristina Marusic's revelatory inquiry into cancer prevention. In searching for answers, she met remarkable doctors, scientists, and advocates who are upending our understanding of cancer and how to fight it. They recognize that we will never reduce cancer rates without ridding our lives of the chemicals that increasingly trigger this deadly disease. Most never imagined this role for themselves. One scientist grew up without seeing examples of Indian-American women in the field, yet went on to make shocking discoveries about racial disparities in cancer risk. Another leader knew her calling was children's health, but realized only later in her career that kids can be harmed by invisible pollutants at their daycares. Others uncovered surprising links between cancer and the everyday items that fill our homes and offices. For these individuals, the fight has become personal. And it certainly is personal for Berry, a young woman whose battle with breast cancer is woven throughout these pages. Might Berry have dodged cancer had she not grown up in Oil City, Pennsylvania, in the shadow of refineries? There is no way to know for sure. But she is certain that, even with the best treatment available, her life was changed irrevocably by her diagnosis. Marusic shows that, collectively, we have the power to prevent many cases like Berry's. The war on cancer is winnable—if we revolutionize the way we fight.

Lesbian, Gay, Bisexual, and Transgender (LGBT) also known as sexual and gender minority (SGM) populations have been the focus of global attention. Most importantly, LGBT populations have been addressed in the context of human rights in multiple reports and other activities by the United Nations and other international organizations. There is great variation among countries in the recognition of LGBT individuals'human rights. A global focus on LGBT populations'health is still limited, with the notable exception of HIV research. This book on LGBT populations and cancer in the global context is, therefore, an important step in that it will broaden the focus on LGBT populations'health. Globally, cancer is the second leading cause of death. Cancer morbidity and mortality are increasing disproportionately among populations in lower-income countries. A review conducted by the World Health Organization (WHO) found that of the 82% of member states (158) countries, only 35% of the national cancer control plans addresses vulnerable population, including LGBT populations. These findings reflect an increasing awareness about equity when addressing cancer prevention and control, including LGBT populations. This book addresses LGBT populations'cancer burden across countries that range from high- to low-income countries to support efforts in diverse countries that are working towards reducing LGBT populations'cancer burden. It documents place-specific challenges that impede progress towards reducing the LGBT cancer burden as well as critically assesses the variation in cancer control efforts that target LGBT populations and cancer to support progress at a global scale. This book includes six sections that cover the six WHO regions, with each chapter written by an author from the specific region s/he is covering. Each chapter makes use of a template that contextualizes the region, local data collection/availability, risk factors, cancerprevention, detection, diagnosis, treatment, and survivorship.

This book tells the fascinating story of the relationship of tobacco products to cancer, from the first discoveries to the present day cancer pandemic and regulatory activities. Although there are already excellent books and monographs on this topic, both in the popular press and as government summaries, none relate the scientific story at the level of non-specialist graduate and medical students, researchers, or educated popular science readers. In this book, with a primary focus on the United States, the editors — Stephen S Hecht and Dorothy K Hatsukami — bring together 24 renowned experts on the subject of tobacco and cancer to summarize specific aspects of this critical topic in relatively non-technical terms while also incorporating some personal insights related to the story of the discovery process. This highly authoritative book is also expected to be an excellent teaching tool and basis for a course for graduate and medical students on this important topic.

Cancer: How Lifestyles May Impact Disease Development, Progression, and Treatment explores different processes that influence the efficacy of treatments and what lifestyle and behavioral modification options are available to patients to improve therapy responses, with a focus on addressing their strengths and weaknesses. The book discusses mechanisms by which particular lifestyles may affect cancer processes, including various aspects of immune functioning, inflammatory and energy-related processes, reactive oxygen species, hormonal and neurotransmitter mechanisms, the role of neurotrophins, and microbial effects. Considerable attention is devoted to the impact of psychosocial processes that indirectly affect disease occurrence, and to behavioral change methods. - Focuses on the link between lifestyle factors (eating/diet, exercise, sleep, circadian rhythms, and stressors) in the development and progression of various types of cancer - Addresses the contributions of lifestyle behavior to the efficacy and moderation of cancer treatments and their side effects - Delineates mechanisms by which particular lifestyles may come to affect the cancer process

Fundamentals of Cancer Detection, Treatment, and Prevention The professional guide to cancer diagnosis and therapy for researchers and clinicians In Fundamentals of Cancer Detection, Treatment, and Prevention, distinguished researcher Surya K. De delivers a concise and authoritative guide to cancer treatment, diagnosis, and prevention. The book offers a comprehensive overview of cancer in humans, from its causes, symptoms, and diagnosis to the variety of treatment options available today. Intuitively organized by cancer type, this guide provides concise information on risk factors, diagnosis, and treatment options for all commonly encountered tumors, including surgery, radiation therapy, chemotherapy, and immunotherapy. All US FDA-approved drugs—like small molecules, peptides, monoclonal antibodies, whole antibodies, gene therapy, antibody-drug conjugates, and cell therapies—are considered, and information about their generic and brand names, clinical uses, and mechanisms of action is presented. Readers will also find: A thorough overview of human cancers, including cancer risk factors and possible preventions Comprehensive explorations of bladder, blood, brain, and spinal cord cancers Practical discussions of breast, colorectal, cervical, kidney, and liver cancer In-depth examinations of lung, skin, ovarian, vaginal, vulvar, pancreatic, and prostate cancers, as well as mesothelioma Perfect for pharmaceutical chemists, oncologists, pharmacologists, and medicinal chemists, Fundamentals of Cancer Detection, Treatment, and Prevention is an indispensable guide for professional researchers, whether they are working in the clinic or the pharmaceutical industry.

Topics in Anti-Cancer Research covers new developments in the field of cancer diagnosis and drug therapy. Novel drugs as anticancer agents include natural and synthetic phenazirines and other anti-cancer compounds. The series also covers information on the current understanding of the pathology and molecular biology of specific neoplasms. The diversity of research topics published in this book series give broad and valuable perspectives for cancer researchers, clinicians, cancer professionals aiming to develop novel anti-cancer targets and patents for the treatment of various cancers. The topics covered in this volume are: - Peptides can play a major role in combating cancer diseases - Studying of the CLL after treatment using fractal parameter of neoplastic lymphocytes detection (ΛNLD) - Mechanistic insight of rhenium-based compounds as anti- cancer agents - Targeting cancer-specific inflammatory components in cancer therapeutics - Marine natural products as a source of novel anticancer agents: a treasure from the ocean - PDX clinical trial design in anti-cancer research

This book, in a new, extensively updated edition, covers viral infection, virus-induced inflammation and tissue injuries, viral epidemiology, oncogenic mechanisms, and current and emerging preventive and therapeutic strategies in detail. Readers will also find information on the individual aspects of a number of oncogenic viruses, including hepatitis B, hepatitis C, human papillomavirus, Epstein–Barr virus, human T-cell lymphotropic virus, Kaposi sarcoma-associated herpes, and Merkel cell polyomavirus, as well as associated human cancers. The book will benefit all those who are seeking a comprehensive, up-to-date overview of the basic and clinical aspects of oncogenic viruses and associated human cancers. Following its original publication in 2014, the first edition of this book quickly became an influential text in the field. This second edition duly reflects the significant advances in knowledge and research that have been achieved in the years since.

This useful reference provides solid knowledge of the risks and benefits associated with the cancer screening process, assesses abnormal results and therapeutic outcomes, and facilitates the communication of these issues to patients. Describes screening tests from individual, health care, ethical, legal, and regulatory perpectives! Gatherin

Something everyone has the power to do is reduce your cancer risk, and this book will show you just how easy it is to do it.Each year, over a million people in the United States alone hear the words no one ever wants to hear: You have cancer. But what if there was a way for fewer people to hear these words?One of the biggest myths regarding cancer is that it's mostly genetic - meaning that you have no control over whether you get it. While genetics do have an impact, the truth is that your lifestyle and environment play the major role.Physician and Chief Medical Offer of WebMD John Whyte, MD, MPH, shares straightforward information and equips you with strategies to help you on a journey to better health.In Take Control of Your Cancer Risk, Dr. Whyte provides helpful tips including:assessing your cancer riskknowing which screenings you need, and whenlearning the role food, exercise, and sleep playunderstanding the relationship between stress and cancerTake Control of Your Cancer Risk is filled with practical advice that empowers you to really take control of our health.

An unprecedented constellation of experts—leading cancer doctors, policymakers, cutting-edge researchers, national advocates, and more—explore the legacy and the shortcomings from the fifty-year war on cancer and look ahead to the future.The longest war in the modern era, longer than the Cold War, has been the war on cancer. Cancer is a complex, evasive enemy, and there was no quick victory in the fight against it. But the battle has been a monumental test of medical and scientific research and fundraising acumen, as well as a moral and ethical challenge to the entire system of medicine. In A New Deal for Cancer, some of today's leading thinkers, activists, and medical visionaries describe the many successes in the long war and the ways in which our deeper failings as a society have held us back from a more complete success.Together they present an unrivaled and nearly complete map of the battlefield across dimensions of science, government, equity, business, the patient provider experience, and more, documenting our emerging understanding of cancer's many unique dimensions and offering bold new plans to enable the American health care system to deliver progress and hope to all patients.

Cancer diagnosis and treatment doesn't have to be a passive experience, and it shouldn't be. Dr. Kathryn Schmitz's Moving Through Cancer introduces a 21-day program of strength training and exercise for cancer prevention and recovery.Go from diagnosis to thriving with this empowering guide to using strength training and exercise to improve your mental and physical health before, during, and after cancer diagnosis and treatment.This groundbreaking program will show you how to use exercise and movement to:• Recover more quickly from surgery• Withstand chemotherapy (or other drug treatments) or radiation with fewer side effects• Bounce back to daily life following cancer treatments• Prevent loss of function or fitness due to treatment• Return to work more quickly or stay at work throughout treatment• Protect against late side effects of treatment that come years after diagnosisLeading exercise oncology researcher Dr. Kathryn Schmitz shows you how to prepare for cancer treatment and begin regularly exercising in just 21 days using five key steps: Move, Lift, Eat, Sleep, and Log. Both informative and practical, Moving Through Cancer explains the science of healing and prevention and delivers a paradigm-shifting message for patients, doctors, and caregivers about using exercise to live with and beyond cancer.FOR READERS OF: Anticancer Living and The Cancer-Fighting Kitchen.A PRACTITIONER AND CAREGIVER: Dr. Kathryn Schmitz is a pracademic (practitioner + academic) and a caregiver: In 2010, the publication of one of her trials in The New England Journal of Medicine and the Journal of the American Medical Association overturned years of entrenched dogma and conventional wisdom that told breast cancer survivors to avoid upper body exercise. In 2016, Dr. Schmitz's wife, Sara, was diagnosed with stage 3 squamous cell carcinoma—she is currently NED (no evidence of disease) and cancer free. Moving Through Cancer is inspired by Dr. Schmitz's professional and personal experience with cancer.HELPS PATIENTS AND CAREGIVERS TO COMBAT THE POWERLESSNESS OF THE CANCER JOURNEY: Dr. Schmitz's empowering message will not only resonate with anyone who has been diagnosed with cancer but with their family and loved ones as well. Dr. Schmitz is able to give life back to readers by providing results that include better sleep, better sex, less chemo brain, reduced nausea, and improved recovery.PARADIGM-SHIFTING PROTOCOL: Moving Through Cancer is the center of Dr. Schmitz's campaign to have doctors prescribing exercise to cancer patients as common practice by 2029.THE FIRST MAINSTREAM EXERCISE-FOR-CANCER BOOK: Until now, exercise-for-cancer books have been limited to academic approaches or one-cancer-specific (breast) or one-exercise specific (yoga, pilates) books. Moving Through Cancer is for all cancer patients and survivors and their caregivers.GREAT FOR THE CLASSROOM: Students and teachers will want to use these techniques in their classrooms to provide a better understanding of how to treat cancer patients.Perfect for: 18+, Health enthusiasts, rehab, exercise, academia, medical professionals

This book discusses the efficacy of various naturally occurring chemopreventive agents in preventing or delaying cancer. It focuses on the holistic chemopreventive concept, demonstrating the relevant response is the combined effect of a series of compounds that alone have been shown to have some effect in different experimental models. Written by leading experts in the field, the contributions provide details of research on various chemopreventive agents. Offering insights into the unique molecular targets and mechanisms, safety issues, molecular efficacy, and occurrence in nature of these compounds, the book is a valuable resource for all scientists working in biomedicine, and specifically in cancer research.

Functional Foods in Cancer Prevention and Therapy presents the wide range of functional foods associated with the prevention and treatment of cancer. In recent decades, researchers have made progress in our understanding of the association between functional food and cancer, especially as it relates to cancer treatment and prevention. Specifically, substantial evidence from epidemiological, clinical and laboratory studies show that various food components may alter cancer risk, the prognosis after cancer onset, and the quality of life after cancer treatment. The book documents the therapeutic roles of well-known functional foods and explains their role in cancer therapy. The book presents complex cancer patterns and evidence of the effective ways to control cancers with the use of functional foods. This book will serve as informative reference for researchers focused on the role of food in cancer prevention and physicians and clinicians involved in cancer treatment. - Discusses the role of functional foods in cancer therapy - Presents research-based evidence of the role of herbs and bioactive foods in cancer treatment and prevention - Provides the most current, concise, scientific information regarding the efficacy of functional foods in preventing cancer and improving the quality of life - Explores antioxidants, phytochemicals, nutraceuticals, herbal medicine and supplements in relation to cancer prevention and treatment - Contains a clinical approach to the use of functional foods to prevent and treat cancer - Emphasizes the role and mechanism of functional foods, including the characterization of active compounds on cancer prevention and treatment

Cancer is a major global public health problem. Among different environmental and lifestyle factors contributing to cancer risk, diet is a key one. On the one hand, obesity and increased consumption of red and processed meat, ethanol, sugar and saturated fatty acids are associated with increased cancer risk. On the other hand, consumption of micronutrients such as vitamin D, selenium, zinc, folate and bioactive compounds from fruits and vegetables is associated with decreased risk. Written by an influential, international team of experts, this book presents and discusses current topics on nutrition and cancer prevention. It covers both nutritional influences on different cancers plus specific chapters on the commonly occurring cancers. Nutritional genomics-based studies show that some dietary components modulate carcinogenesis through complex cellular and molecular mechanisms. A better understanding of these different cellular and molecular mechanisms is needed to establish efficient dietary recommendations for cancer prevention. This book will provide such an understanding, serving as an important book for all those working in nutritional health, food science and cancer research.

Biomaterials for Cancer Therapeutics: Evolution and Innovation, Second Edition, discusses the role and potential of biomaterials in treating this prevalent disease. The first part of the book discusses the fundamentals of biomaterials for cancer therapeutics. Part Two discusses synthetic vaccines, proteins and polymers for cancer therapeutics. Part Three focuses on theranosis and drug delivery systems, while the final set of chapters look at biomaterial therapies and cancer cell interaction. Cancer affects people of all ages, and approximately one in three people are estimated to be diagnosed with cancer during their lifetime. Extensive research is being undertaken by many different institutions to explore potential new therapeutics, and biomaterials technology is being developed to target, treat and prevent cancer. Hence, this book is a welcomed resource to the discussion. - Provides a complete overview of the latest research into the potential of biomaterials for the diagnosis, treatment and prevention of cancer - Discusses how the properties of specific biomaterials make them important in cancer treatment - Covers synthetic vaccines, proteins and polymers for cancer therapeutics

Human Papillomavirus: Proving and Using a Viral Cause for Cancer presents a steady and massive accumulation of evidence about the role of HPV and prevention of HPV-induced cancer, along with the role and personal commitment of many scientists of different backgrounds in establishing global relevance. This exercise involved years of personal commitment to proving or disproving an idea that aroused initial skepticism, and that still has difficult implications for some. It remains one of the big successes of medicine that exploited both established medical science dating back to the nineteenth century and new molecular genetic science during a time of transition in medicine. - Presents a comprehensive, up-to-date review of the role of HPV in cancer from those involved in its study - Includes the way evidence on the role and utility of HPV based prevention has been accumulated over almost 40 years - Gives a series of vignettes of individual scientists involved in the development of the science of HPV and cancer at different stages and their experiences and reasons for involvement

Topics in Anti-Cancer Research covers new developments in the field of cancer diagnosis and drug therapy. Novel drugs as anticancer agents include natural and synthetic phenazirines and other anti-cancer compounds. The series also covers information on the current understanding of the pathology and molecular biology of specific neoplasms. The diversity of research topics published in this book series give broad and valuable perspectives for cancer researchers, clinicians, cancer professionals aiming to develop novel anti-cancer targets and patents for the treatment of various cancers. The topics covered in this volume are: - Recent Patents on Exosome-Derived Therapeutic Agents - Serrated Lesions of the Colon and Rectum: An Overview of Pathology and Emphasis on a New Classification - Introducing the 188W/188Re and 144Ce/144Pr Plaques for Eye Cancers Brachytherapy - ShcA Family of Adaptor Proteins: Dual Role in Cell Growth - Hormones Management as Anticancer Treatment and Protection: Functions and Mechanism of Action

Epigenetics of Cancer Prevention, Volume Ten is the first to look at epigenetics and chemoprevention together. Although there is numerous scientific data available on how epigenetics can lead to cancer and how chemoprevention can be beneficial in the treatment of, or improvement of quality of life, together they will set an advanced understanding for the reader in this upcoming field of chemoprevention influencing epigenetics. This book discusses molecular epigenetic targets of natural products, such as green tea polyphenols, curcumin and resveratrol, and organ specific epigenetic targets related to diverse types of cancer, for example prostate, colorectal, breast, lung and skin cancers. Additionally, it encompasses a discussion on research methods and limitations to study epigenetics and epigenomics of chemopreventive drugs and personalized cancer treatment with phytochemicals. The book is ideal for cancer researchers, health care professionals and all individuals who are interested in cancer prevention research and its clinical applications, especially in natural remedies. - Lists natural agents, including nutraceuticals, and their effects on normal or tumor genome - Addresses various epigenetic systems and mechanisms in the regulation and support of the mammalian genome - Discusses how various parts of dietary phytochemicals can influence or modify epigenetic mechanisms in several types of cancer

Topics in Anti-Cancer Research Volume 8 covers new developments in the field of cancer. Novel drugs as anticancer agents include natural and synthetic phenazines and other anti-cancer compounds. It also encompasses the role of estrogen as endocrine disruptors and strategies targeting cancer stem cells for the treatment of different types of cancers, including myeloma and renal cell cancer. The diversity of researches and topics published in this eBook Series will be valuable to cancer researchers, clinicians, and cancer professionals aiming to develop novel anti-cancer targets for the treatment of various cancers. The topics covered in the eighth volume of this series are as follows: -Novel Drugs for Multiple Myeloma -Synthetic Estrogens are Endocrine Disruptors via Inhibition of AF1 Domain of ERs -Recent Progress of Phenazines as Anticancer Agents -Cancer Stem Cell Targeting for Anticancer Therapy: Strategies and Challenges

This authoritative work, now in its fourth edition, presents state of the art knowledge on all key aspects of cancer prevention. In addition to detailed summaries on preventive strategies for specific cancers, readers will find current knowledge on a range of relevant scientific topics including the benefits of cancer prevention, the importance of diet and physical activity, innate and adaptive immune responses to cancer, hereditary risks, cancer health disparities, and the preventive role of telemedicine. In this new edition of the book, the coverage has been expanded to include additional disease sites and to provide up-to-date information across the range of disciplines in the field of cancer prevention and control. Written as a collaborative work by internationally recognized leaders in the field, Fundamentals of Cancer Prevention is an essential reference guide and tool for oncologists, primary care physicians, the research community, and students with an interest in reducing the burden of cancer through the implementation of effective preventive strategies.

The book discusses cancer and the potential use of phytochemicals as cancer therapeutics. It begins with the basics of cancer, including the definition, types, etiology and molecular mechanisms involved, before discussing the fundamentals of diagnosis, treatment and associated problems as well as remedial measures. Since cancer is not a single disease, and the mechanisms of carcinogenesis are different for different cancers, it examines the genes and proteins involved in carcinogenesis, and signal transduction pathways for each individual cancer type. Further, the book reviews the latest research on phytochemicals for cancer treatment, highlighting their anti-cancer properties, sources, structure, active biomolecules and probable mechanisms of action, and describing their biochemical properties in the context of cancer prevention and treatment.

Dietary supplements and nutraceuticals such as Vitamin A and D, Omega-3 and probiotics are used as part of the cancer treatment as complimenting the main therapy. Several Nutraceuticals have shown to boost the immune responses, while emerging clinical studies and other research suggests that some plant-based agents may, indeed, impact late-stage cancer, influencing molecular processes corrupted by tumor cells to evade detection, expand clonally, and invade surrounding tissues. Advances in Nutraceutical Applications in Cancer: Recent Research Trends and Clinical Applicationsis an attempt to collect evidence and related clinical information of application of Nutraceuticals to be used in cancer treatment or compliment the cancer treatment. It contains 16 chapters written by experts in related field's and covers many different aspects of the formulation and development of Nutraceuticals for cancer applications. This book covers efficacy, safety and toxicological aspects of nutraceuticals. It also addresses various novel drug delivery systems of nutraceuticals with anticancer properties, as well as nutraceuticals as supplements for cancer prevention. Features: Offers a comprehensive view of neutraceuticals'role in cancer prevention and treatment Covers the applications and implications of neutraceuticals in prostate, colorectal, breast and gynecological cancers Discusses the principles of neutrigenomics and neutrigenetics in cancer prevention Explors the role of probiotics and micronutrients in cancer treatment and prevention Nutraceuticals can alter the gut microbiota. Gut microbiome undergoes changes during the disease status and followed by the cancer treatment. Nutraceutical's role in proliferation and prevention of gynecological cancers, nutraceutical's role in proliferation and prevention of prostate cancer and role of micronutrients in cancer prevention, both pros and cons, are some of the topics discussed in various chapters in this book. This book is addressed to scientists, clinicians, and students who are working in the area of Nutraceutical applications in cancer treatment.

Près d'un décès sur 6 dans le monde est dû au cancer. Cette maladie qui a fait 8,8 millions de morts en 2015 touche toutes les populations, à tous les âges. Le nombre de cas ne cesse d'augmenter et l'impact économique est considérable. Actuellement on estime que 30 à 50% des cancers pourraient être évités en agissant sur les principaux facteurs de risque notamment comportementaux et alimentaires. Pourtant, entre surmédiatisation et informations parfois contradictoires, il est souvent difficile de s'y retrouver. Cet ouvrage cherche à accompagner le lecteur dans la compréhension des liens entre alimentation et cancer : Qu'est-ce que le cancer? De quelle façon nos comportements alimentaires peuvent influer sur son développement? Comment mettre ces connaissances en pratique au quotidien pour allier équilibre, praticité et plaisir?

An oncologist's integrative path to treating and living better with or beyond cancer Dr. M. Laura Nasi presents a new way of looking at how we view and treat cancer. With current advances in medicine, we're learning more about the ways different aspects of our lives and health impact and interact with one another—why does one long-term smoker get diagnosed with stage-4 lung cancer while another remains cancer-free? Why does someone exposed to a known carcinogen get sick while someone else is apparently immune? What seemingly unrelated factors end up playing key roles in disease etiology, progression, and prognosis? In this well-researched, inspiring, and easy-to-read guide, Dr. Nasi offers an integrative, whole-person approach to cancer, and explains how it is a systemic disease manifesting a global condition locally. Conventional medicine focuses on attacking malignant cells. Integrative medicine encourages chemo and radiation when necessary, while also focusing on a patient's internal balance to help halt the disease. Nasi draws on the latest research on the PNIE (psycho-neuro-immuno-endocrine) network to help our systems recognize, repair, or eliminate the cancer cells, focusing on nutrition, stress management, exercise, adequate sleep, healthy relationships, and other body/mind/spirit modalities. Dr. Nasi encourages patients to become empowered agents of their own care.

Près de 40% des cancers ont des causes évitables. Alors quels sont les produits et les comportements à risque? Quelles stratégies mettre en œuvre?L'ouvrage décrypte avec précision les causes connues du cancer pour que chacun puisse évaluer son propre risque : tabac,alcool, alimentation, soleil, travail, pilule ou traitement hormonal de la ménopause, pollution,pesticides, perturbateurs endocriniens… Savoir d'où vient la menace est fondamental. Quelle quantité d'alcool peut-on boire sans risque? Combien de temps peut-on s'exposer au soleil? Existe-t-il une consommation de tabac acceptable? Faut-il arrêter de manger de la viande?… L'ouvrage décrit dans quelles circonstances, à quelles doses, pour quelle durée, certains éléments de notre vie quotidienne augmentent le risque. Et bien sûr, il offre des conseils de prévention, des pistes pour prendre soin de soi.Ce livre est destiné à tous ceux qui sont prêts à modifier leur mode de vie pour se prémunir au maximum, même si bien sûr, nul ne peut garantir une protection absolue. Oui, il y a des moyens de prévenir certains cancers. Encore faut-il agir en conséquence et en finir avec la politique de l'autruche!Consulter la préface de Jacqueline Godet

Topics in Anti-Cancer Research covers important advances on both experimental preclinical and clinical cancer research in drug development. The book series offers readers an insight into current and future therapeutic approaches for the prevention of d

Developed by the American Cancer Society this new textbook designed for a wide range of learners and practitioners is a comprehensive reference covering the diagnosis of cancer, and a range of related issues that are key to a multidisciplinary approach to cancer and critical to cancer control and may be used in conjunction with the book, The American Cancer Society's Oncology in Practice: Clinical Management. Edited by leading clinicians in the field and a stellar contributor list from the US and Europe, this book is written in an easy to understand style by multidisciplinary teams of medical oncologists, radiation oncologists and other specialists, reflecting day-to-day decision-making and clinical practice. Input from pathologists, surgeons, radiologists, and other specialists is included wherever relevant and comprehensive treatment guidelines are provided by expert contributors where there is no standard recognized treatment. This book is an ideal resource for anyone seeking a deeper understanding of cancer prevention, screening, and follow-up, which are central to the ACS's worldwide mission on cancer control.

The high rate of urbanization and a steady increase in per capita income has improved the socio-economic status of people all over the world. This has resulted in drastic changes in their lifestyle and food consumption patterns, where traditional foods are being replaced with more ready-made junk foods with few servings of fresh vegetables and fruits. It has been postulated that industrialization has caused change in food choice, dietary pattern modification and resulted in a sedentary lifestyle. In addition, contaminated foods with unsafe microbes and chemical hazards are increasing. All of these events have resulted in an increased risk of cancer, the leading cause of mortality and morbidity worldwide.This book will provide a basic understanding of cancer, its risk factors, preventive measures, and possible treatments currently available, as well as identifying the different dietary factors that might synergize with a sedentary lifestyle in the etiology of cancer, and its prevention measure.